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Murai, Masatoshi

Graduate School of Agriculture, Division of Applied Life Sciences Associate Professor

Murai, Masatoshi
list
    Last Updated :2022/09/30

    Basic Information

    Faculty

    • 農学部

    Professional Memberships

    • Japan Bioenergetics Group
    • Pesticide Science Society of Japan
    • Japan Society for Bioscience, Biotechnology, and Agrochemistry

    Academic Degree

    • 修士(農学)(京都大学)
    • 博士(農学)(京都大学)

    Academic Resume (Undergraduate School/Majors)

    • 京都大学, 農学部生物機能科学科, 卒業

    High School

    • High School

      滋賀県立彦根東高等学校

    Research History

    • From Aug. 2018, To Present
      Kyoto University, Graduate School of Agriculture, Associate Professor
    • From Apr. 2009, To Jul. 2018
      Kyoto University, Graduate School of Agriculture, Assistant Professor
    • From Apr. 2007, To Mar. 2009
      Japan Society for the Promotion of Science, JSPS research fellow (DC2)

    Profile

    • Profile

      Mitochondria are organelles that play an important role in oxidative phosphorylation (ATP production) in eukaryotic cells. They contain a series of respiratory chain complexes, ATP synthase, and membrane transporters, whose structural and functional insights have remained elusive. We are investigating the structure and function of such membrane proteins, which are intimately involved in energy metabolism, through chemical biology approaches.


      Current research themes are as follows;

      1. Exploring the inhibitor-binding site in mitochondrial NADH-quinone oxidoreductase (complex I).

      2. Identification of the quinone/inhibitor-binding site in various redox enzymes involving in energy metabolism.

      3. Screening and mode of action study of the chemicals targeting mitochondrial membrane transporters.

    Language of Instruction

    • English

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2022/09/30

      Research

      Research Topics, Overview of the research

      • Research Topics

        1. Exploring the inhibitor-binding site in mitochondrial NADH-quinone oxidoreductase (complex I).
        2. Identification of the quinone/inhibitor-binding site in various redox enzymes involving in energy metabolism.
        3. Screening and mode of action study of the chemicals targeting mitochondrial membrane transporters.
      • Overview of the research

        Mitochondria are organelles that play an important role in oxidative phosphorylation (ATP production) in eukaryotic cells. They contain a series of respiratory chain complexes, ATP synthase, and membrane transporters, whose structural and functional insights have remained elusive. We are investigating the structure and function of such membrane proteins, which are intimately involved in energy metabolism, through chemical biology approaches.

      Research Interests

      • Chemical Biology
      • Respiratory complex I
      • Ubiquinone
      • Photoaffinity labeling
      • Organic Synthesis
      • Respiratory chain
      • Bioorganic chemistry
      • Biological organic chemistry

      Research Areas

      • Life sciences, Bioorganic chemistry

      Papers

      • Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Jun-ichi Kishikawa; Moe Ishikawa; Takahiro Masuya; Masatoshi Murai; Yuki Kitazumi; Nicole L. Butler; Takayuki Kato; Blanca Barquera; Hideto Miyoshi
        Nature Communications, Jul. 2022, Peer-reviewed
      • Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I
        Shinpei Uno; Takahiro Masuya; Oleksii Zdorevskyi; Ryo Ikunishi; Kyoko Shinzawa-Itoh; Jonathan Lasham; Vivek Sharma; Masatoshi Murai; Hideto Miyoshi
        Journal of Biological Chemistry, May 2022, Peer-reviewed
      • Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I
        Daniel N. Grba; James N. Blaza; Hannah R. Bridges; Ahmed-Noor A. Agip; Zhan Yin; Masatoshi Murai; Hideto Miyoshi; Judy Hirst
        Journal of Biological Chemistry, Mar. 2022, Peer-reviewed
      • Comprehensive understanding of multiple actions of anticancer drug tamoxifen in isolated mitochondria
        Yufu Unten; Masatoshi Murai; Tomoki Koshitaka; Kotaro Kitao; Osamu Shirai; Takahiro Masuya; Hideto Miyoshi
        Biochimica et Biophysica Acta (BBA) - Bioenergetics, Dec. 2021, Peer-reviewed
      • Natural tetramic acids elicit multiple inhibitory actions against mitochondrial machineries presiding over oxidative phosphorylation
        Yufu Unten; Masatoshi Murai; Katsuyuki Sakai; Yukihiro Asami; Takenori Yamamoto; Takahiro Masuya; Hideto Miyoshi
        Bioscience, Biotechnology, and Biochemistry, 08 Oct. 2021, Peer-reviewed, Corresponding author
      • Traminines A and B, produced by Fusarium concentricum, inhibit oxidative phosphorylation in Saccharomyces cerevisiae mitochondria
        Katsuyuki Sakai; Yufu Unten; Aoi Kimishima; Kenichi Nonaka; Takumi Chinen; Kazunari Sakai; Takeo Usui; Kazuro Shiomi; Masato Iwatsuki; Masatoshi Murai; Hideto Miyoshi; Yukihiro Asami; Satoshi Ōmura
        Journal of Industrial Microbiology and Biotechnology, 03 Aug. 2021, Peer-reviewed
      • Specific chemical modification explores dynamic structure of the NqrB subunit in Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Moe Ishikawa; Takahiro Masuya; Hinako Tanaka; Wataru Aoki; Noam Hantman; Nicole L. Butler; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        Biochimica et Biophysica Acta (BBA) - Bioenergetics, Apr. 2021, Peer-reviewed
      • Pinpoint Dual Chemical Cross-Linking Explores the Structural Dynamics of the Ubiquinone Reaction Site in Mitochondrial Complex I
        Takahiro Masuya; Shinpei Uno; Masatoshi Murai; Hideto Miyoshi
        Biochemistry, 16 Mar. 2021, Peer-reviewed
      • Inhibitors of a Na+-pumping NADH-ubiquinone oxidoreductase play multiple roles to block enzyme function
        Takahiro Masuya; Yuki Sano; Hinako Tanaka; Nicole L Butler; Takeshi Ito; Tatsuhiko Tosaki; Joel E. Morgan; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        Journal of Biological Chemistry, 20 Jul. 2020, Peer-reviewed
      • Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones.
        Kento Tsukada; Shono Shinki; Akiho Kaneko; Kazuma Murakami; Kazuhiro Irie; Masatoshi Murai; Hideto Miyoshi; Shingo Dan; Kumi Kawaji; Hironori Hayashi; Eiichi N Kodama; Aki Hori; Emil Salim; Takayuki Kuraishi; Naoya Hirata; Yasunari Kanda; Teigo Asai
        Nature communications, 14 Apr. 2020, Peer-reviewed
      • IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism
        Tsuji A; Akao T; Masuya T; Murai M; Miyoshi H
        The Journal of Biological Chemistry, Apr. 2020, Peer-reviewed
      • Exploring the binding pocket of quinone/inhibitors in mitochondrial respiratory complex I by chemical biology approaches
        Murai, M
        Biosci. Biotechnol. Biochem., Apr. 2020, Peer-reviewed, Invited, Lead author, Corresponding author
      • Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I
        Uno S; Masuya T; Shinzawa-Itoh K; Lasham J; Haapanen O; Shiba T; Inaoka DK; Sharma V; Murai M; Miyoshi H
        The Journal of Biological Chemistry, Feb. 2020, Peer-reviewed
      • Photoaffinity labeling of respiratory complex I in bovine heart submitochondrial particles by photoreactive [125I]amilorides
        Murai M; Miyoshi H
        Bio-protocol, Sep. 2019, Peer-reviewed, Invited
      • Fusaramin, an antimitochondrial compound produced by Fusarium sp., discovered using multidrug-sensitive Saccharomyces cerevisiae.
        Katsuyuki Sakai; Yufu Unten; Masato Iwatsuki; Hirotaka Matsuo; Wataru Fukasawa; Tomoyasu Hirose; Takumi Chinen; Kenichi Nonaka; Takuji Nakashima; Toshiaki Sunazuka; Takeo Usui; Masatoshi Murai; Hideto Miyoshi; Yukihiro Asami; Satoshi Ōmura; Kazuro Shiomi
        The Journal of antibiotics, Sep. 2019, Peer-reviewed
      • The antibiotic korormicin A kills bacteria by producing reactive oxygen species
        Maynard A; Butler N L; Ito T; da Silva A J; Murai M; Chen T; Koffas M A G; Miyoshi H; Barquera B
        Journal of Bacteriology, May 2019, Peer-reviewed
      • Defining the mechanism of action of S1QELs, specific suppressors of superoxide production in the quinone-reaction site in mitochondrial complex I
        Banba A; Tsuji A; Kimura H; Murai M; Miyoshi H
        The Journal of Biological Chemistry, Apr. 2019, Peer-reviewed
      • Pentenediol-type compounds specifically bind to voltage-dependent anion channel 1 in Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Yamamoto T; Watanabe A; Ichimaru N; Aburaya S; Aoki W; Shinohara Y; Miyoshi H
        Biochemistry, Feb. 2019, Peer-reviewed
      • Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I by chemical biology approaches,
        Uno S; Kimura H; Murai M; Miyoshi H
        The Journal of Biological Chemistry, Jan. 2019, Peer-reviewed
      • Epoxycyclohexenedione-Type Compounds Make Up a New Class of Inhibitors of the Bovine Mitochondrial ADP/ATP Carrier
        Ayaki Aoyama; Masatoshi Murai; Naoya Ichimaru; Shunsuke Aburaya; Wataru Aoki; Hideto Miyoshi
        Biochemistry, 13 Feb. 2018, Peer-reviewed
      • Pinpoint Chemical Modification of the Quinone-Access Channel of Mitochondrial Complex I via a Two-Step Conjugation Reaction
        Takahiro Masuya; Masatoshi Murai; Takeshi Ito; Shunsuke Aburaya; Wataru Aoki; Hideto Miyoshi
        BIOCHEMISTRY, Aug. 2017, Peer-reviewed
      • Identification of the binding sites for ubiquinone and inhibitors in the Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae by photoaffinity labeling
        Takeshi Ito; Masatoshi Murai; Satoshi Ninokura; Yuki Kitazumi; Katherine G. Mezic; Brady F. Cress; Mattheos A. G. Koffas; Joel E. Morgan; Blanca Barquera; Hideto Miyoshi
        JOURNAL OF BIOLOGICAL CHEMISTRY, May 2017, Peer-reviewed
      • Characterization of the ubiquinone-binding protein Coq10 using a synthetic ubiquinone probe (in Japanese)
        Murai M; Miyoshi H
        Japanese Journal of Pesticide Science, Feb. 2017, Peer-reviewed, Invited
      • Action mechanism of the inhibitors of mitochondrial respiratory complex I based on structure-activity relationship (SAR) studies (in Japanese)
        Miyoshi H; Murai M
        Japanese Journal of Pesticide Science, Feb. 2017, Peer-reviewed, Invited
      • Synthetic Ubiquinones Specifically Bind to Mitochondrial Voltage-Dependent Anion Channel 1 (VDAC1) in Saccharomyces cerevisiae Mitochondria
        Masatoshi Murai; Ayaka Okuda; Takenori Yamamoto; Yasuo Shinohara; Hideto Miyoshi
        BIOCHEMISTRY, Jan. 2017, Peer-reviewed
      • Characterization of the reaction of decoupling ubiquinone with bovine mitochondrial respiratory complex I
        Takahiro Masuya; Kenji Okuda; Masatoshi Murai; Hideto Miyoshi
        BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Aug. 2016, Peer-reviewed
      • Current topics on inhibitors of respiratory complex I
        Masatoshi Murai; Hideto Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Jul. 2016, Peer-reviewed
      • Specific Methylation of Asp160 (49 kDa subunit) Located inside the Quinone Binding Cavity of Bovine Mitochondrial Complex I
        Masatoshi Murai; Hiroyuki Inaoka; Takahiro Masuya; Shunsuke Aburaya; Wataru Aoki; Hideto Miyoshi
        BIOCHEMISTRY, Jun. 2016, Peer-reviewed
      • Current topics on inhibitors of respiratory complex I.
        Murai M; Miyoshi H
        Biochimica et biophysica acta, Jun. 2016, Peer-reviewed
      • Reduction of Synthetic Ubiquinone QT Catalyzed by Bovine Mitochondria! Complex I Is Decoupled from Proton Translocation
        Kenji Okuda; Masatoshi Murai; Shunsuke Aburaya; Wataru Aoki; Hideto Miyoshi
        BIOCHEMISTRY, Jan. 2016, Peer-reviewed
      • Ascosteroside C, a new mitochondrial respiration inhibitor discovered by pesticidal screening using recombinant Saccharomyces cerevisiae
        Takuya Suga; Yukihiro Asami; Shohei Hashimoto; Kenichi Nonaka; Masato Iwatsuki; Takuji Nakashima; Ryohei Sugahara; Takahiro Shiotsuki; Takenori Yamamoto; Yasuo Shinohara; Naoya Ichimaru; Masatoshi Murai; Hideto Miyoshi; Satoshi Omura; Kazuro Shiomi
        JOURNAL OF ANTIBIOTICS, Oct. 2015, Peer-reviewed
      • Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I
        Masatoshi Murai; Sayako Habu; Sonomi Murakami; Takeshi Ito; Hideto Miyoshi
        BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Jul. 2015, Peer-reviewed
      • Identification of the Binding Position of Amilorides in the Quinone Binding Pocket of Mitochondrial Complex I
        Takeshi Ito; Masatoshi Murai; Hironobu Morisaka; Hideto Miyoshi
        BIOCHEMISTRY, Jun. 2015, Peer-reviewed
      • Amilorides Bind to the Quinone Binding Pocket of Bovine Mitochondrial Complex I
        Masatoshi Murai; Sonomi Murakami; Takeshi Ito; Hideto Miyoshi
        BIOCHEMISTRY, May 2015, Peer-reviewed
      • Trichopolyn VI: a new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system
        Takuya Suga; Yukihiro Asami; Shohei Hashimoto; Kenichi Nonaka; Masato Iwatsuki; Takuji Nakashima; Yoshihiro Watanabe; Ryohei Sugahara; Takahiro Shiotsuki; Takenori Yamamoto; Yasuo Shinohara; Naoya Ichimaru; Masatoshi Murai; Hideto Miyoshi; Satoshi Omura; Kazuro Shiomi
        JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, 2015, Peer-reviewed
      • Pinpoint Chemical Modification of Asp160 in the 49 kDa Subunit of Bovine Mitochondrial Complex I via a Combination of Ligand-Directed Tosyl Chemistry and Click Chemistry
        Takahiro Masuya; Masatoshi Mural; Hironobu Morisaka; Hideto Miyoshi
        BIOCHEMISTRY, Dec. 2014, Peer-reviewed
      • Chemical modifications of respiratory complex I for structural and functional studies
        Masatoshi Murai; Hideto Miyoshi
        JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, Aug. 2014, Peer-reviewed
      • Identification of the Binding Site of the Quinone-Head Group in Mitochondrial Coq10 by Photoaffinity Labeling
        Masatoshi Murai; Kohei Matsunobu; Sawako Kudo; Kentaro Ifuku; Makoto Kawamukai; Hideto Miyoshi
        BIOCHEMISTRY, Jun. 2014, Peer-reviewed
      • Site-Specific Chemical Labeling of Mitochondrial Respiratory Complex I through Ligand-Directed Tosylate Chemistry
        Takahiro Masuya; Masatoshi Murai; Kentaro Ifuku; Hironobu Morisaka; Hideto Miyoshi
        BIOCHEMISTRY, Apr. 2014, Peer-reviewed
      • Fenpyroximate Binds to the Interface between PSST and 49 kDa Subunits in Mitochondrial NADH-Ubiquinone Oxidoreductase
        Yusuke Shiraishi; Masatoshi Murai; Naoto Sakiyama; Kentaro Ifuku; Hideto Miyoshi
        BIOCHEMISTRY, Mar. 2012, Peer-reviewed
      • Localization of Ubiquinone-8 in the Na+-pumping NADH: Quinone Oxidoreductase from Vibrio cholerae
        Marco S. Casutt; Ruslan Nedielkov; Severin Wendelspiess; Sara Vossler; Uwe Gerken; Masatoshi Murai; Hideto Miyoshi; Heiko M. Moeller; Julia Steuber
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2011, Peer-reviewed
      • Bis-THF motif of acetogenin binds to the third matrix-side loop of ND1 subunit in mitochondrial NADH-ubiquinone oxidoreductase.
        Nakanishi S; Abe M; Yamamoto S; Murai M; Miyoshi H
        Biochimica et biophysica acta, Sep. 2011, Peer-reviewed
      • Bis-THF motif of acetogenin binds to the third matrix-side loop of ND1 subunit in mitochondrial NADH-ubiquinone oxidoreductase
        Sayo Nakanishi; Masato Abe; Shuhei Yamamoto; Masatoshi Murai; Hideto Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Sep. 2011, Peer-reviewed
      • Exploring Interactions between the 49 kDa and ND1 Subunits in Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I) by Photoaffinity Labeling
        Masatoshi Murai; Yuko Mashimo; Judy Hirst; Hideto Miyoshi
        BIOCHEMISTRY, Aug. 2011, Peer-reviewed
      • Synthesis and characterization of photoaffinity probe of acetogenin, a strong inhibitor of mitochondrial complex I
        Shuhei Yamamoto; Masato Abe; Sayo Nakanishi; Masatoshi Murai; Hideto Miyoshi
        TETRAHEDRON LETTERS, Jun. 2011, Peer-reviewed
      • New insight into mechanism of ROS suppression in single subunit NADH-ibiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae
        YAMASHITA TETSUO; Yu Yang; Eiko Nakamaru-Ogiso; HASHIMOTO Takeshi; Masatoshi Murai; IGARASHI Junsuke; Hideto Miyoshi; Akemi Matsuno-Yagi; Takao Yagi; KOSAKA Hiroaki
        The Journal of Physiological Sciences, Mar. 2011, Peer-reviewed
      • Reaction Mechanism of Single Subunit NADH-Ubiquinone Oxidoreductase (Ndi1) from Saccharomyces cerevisiae EVIDENCE FOR A TERNARY COMPLEX MECHANISM
        Yu Yang; Tetsuo Yamashita; Eiko Nakamaru-Ogiso; Takeshi Hashimoto; Masatoshi Murai; Junsuke Igarashi; Hideto Miyoshi; Nozomu Mori; Akemi Matsuno-Yagi; Takao Yagi; Hiroaki Kosaka
        JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2011, Peer-reviewed
      • Probing the role of tryptophan-derived secondary metabolism in defense responses against Bipolaris oryzae infection in rice leaves by a suicide substrate of tryptophan decarboxylase
        Atsushi Ishihara; Takahito Nakao; Yuko Mashimo; Masatoshi Murai; Naoya Ichimaru; Chihiro Tanaka; Hiromitsu Nakajima; Kyo Wakasa; Hisashi Miyagawa
        PHYTOCHEMISTRY, Jan. 2011, Peer-reviewed
      • Exploring the Binding Site of Delta lac-Acetogenin in Bovine Heart Mitochondrial NADH-Ubiquinone Oxidoreductase
        Nobuyuki Kakutani; Masatoshi Murai; Naoto Sakiyama; Hideto Miyoshi
        BIOCHEMISTRY, Jun. 2010, Peer-reviewed
      • Complementation of coenzyme Q-deficient yeast by coenzyme Q analogues requires the isoprenoid side chain
        Andrew M. James; Helena M. Cocheme; Masatoshi Murai; Hideto Miyoshi; Michael P. Murphy
        FEBS JOURNAL, May 2010, Peer-reviewed
      • Concise procedure for the synthesis of cardiolipins having different fatty acid combinations
        Masato Abe; Shigeki Kitsuda; Shunji Ohyama; Shinya Koubori; Masatoshi Murai; Hideto Miyoshi
        TETRAHEDRON LETTERS, Apr. 2010, Peer-reviewed
      • Characterization of the Ubiquinone Binding Site in the Alternative NADH-Quinone Oxidoreductase of Saccharomyces cerevisiae by Photoaffinity Labeling
        Masatoshi Murai; Tetsuo Yamashita; Mai Senoh; Yuko Mashimo; Michihiko Kataoka; Hiroaki Kosaka; Akemi Matsuno-Yagi; Takao Yagi; Hideto Miyoshi
        BIOCHEMISTRY, Apr. 2010, Peer-reviewed
      • Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I.
        Sekiguchi K; Murai M; Miyoshi H
        Biochimica et biophysica acta, Sep. 2009, Peer-reviewed
      • Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I
        Koji Sekiguchi; Masatoshi Murai; Hideto Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Sep. 2009, Peer-reviewed
      • Characterization of the Inhibitor Binding Site in Mitochondrial NADH-Ubiquinone Oxidoreductase by Photoaffinity Labeling Using a Quinazoline-Type Inhibitor
        Masatoshi Murai; Koji Sekiguchi; Takaaki Nishioka; Hideto Miyoshi
        BIOCHEMISTRY, Feb. 2009, Peer-reviewed
      • Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Naoya Ichimaru; Masatoshi Murai; Nobuyuki Kakutani; Junko Kako; Atsushi Ishihara; Yoshiaki Nakagawa; Takaaki Nishioka; Takao Yagi; Hideto Miyoshi
        BIOCHEMISTRY, Oct. 2008, Peer-reviewed
      • Identification of receptors of main sex-pheromone components of three Lepidopteran species
        Hidefumi Mitsuno; Takeshi Sakurai; Masatoshi Murai; Tetsuya Yasuda; Soichi Kugimiya; Rika Ozawa; Haruhiko Toyohara; Junji Takabayashi; Hideto Miyoshi; Takaaki Nishioka
        EUROPEAN JOURNAL OF NEUROSCIENCE, Sep. 2008, Peer-reviewed
      • Dynamic function of the spacer region of acetogenins in the inhibition of bovine mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Masato Abe; Akina Kubo; Shuhei Yamamoto; Yoshinori Hatoh; Masatoshi Murai; Yasunao Hattori; Hidefumi Makabe; Takaaki Nishioka; Hideto Miyoshi
        BIOCHEMISTRY, Jun. 2008, Peer-reviewed
      • Crucial structural factors and mode of action of polyene Amides as inhibitors for mitochondrial NADH-Ubiquinone oxidoreductase (Complex I)
        Takehiko Yoshida; Masatoshi Murai; Masato Abe; Naoya Ichimaru; Toshiyuki Harada; Takaaki Nishioka; Hideto Miyoshi
        BIOCHEMISTRY, Sep. 2007, Peer-reviewed
      • Synthesis and Inhibitory Action of Novel Acetogenin Mimics Δlac-Acetogenins: A New Class of Inhibitors of Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex-I)
        Hideto Miyoshi; Naoya Ichimaru; Masatoshi Murai
        Pesticide Chemistry: Crop Protection, Public Health, Environmental Safety, 31 May 2007, Peer-reviewed
      • The ND1 subunit constructs the inhibitor binding domain in bovine heart mitochondrial complex I
        Masatoshi Murai; Atsushi Ishihara; Takaaki Nishioka; Takao Yagi; Hideto Miyoshi
        BIOCHEMISTRY, May 2007, Peer-reviewed
      • Mode of inhibitory action of Delta lac-acetogenins, a new class of inhibitors of bovine heart mitochondrial complex I
        Masatoshi Murai; Naoya Ichimaru; Masato Abe; Takaaki Nishioka; Hideto Miyoshi
        BIOCHEMISTRY, Aug. 2006, Peer-reviewed
      • Mode of inhibitory action of Delta lac-acetogenins, a new class of inhibitors of bovine heart mitochondrial complex I
        Masatoshi Murai; Naoya Ichimaru; Masato Abe; Takaaki Nishioka; Hideto Miyoshi
        BIOCHEMISTRY, Aug. 2006, Peer-reviewed
      • Function of the alkyl side chains of Delta lac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase)
        N Ichimaru; M Abe; M Murai; M Senoh; T Nishioka; H Miyoshi
        BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jul. 2006, Peer-reviewed
      • Function of the alkyl side chains of Delta lac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase)
        N Ichimaru; M Abe; M Murai; M Senoh; T Nishioka; H Miyoshi
        BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jul. 2006, Peer-reviewed
      • Light control of mitochondrial complex I activity by a photoresponsive inhibitor
        D Fujita; M Murai; T Nishioka; H Miyoshi
        BIOCHEMISTRY, May 2006, Peer-reviewed
      • Synthesis of (4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin, squamostolide, and their inhibitory action with bovine heart mitochondrial complex I
        H Makabe; Y Kimura; M Higuchi; H Konno; M Murai; H Miyoshi
        BIOORGANIC & MEDICINAL CHEMISTRY, May 2006, Peer-reviewed
      • Synthesis of photolabile Delta lac-acetogenin for lphotoaffinity labeling of mitochondrial complex I
        M Murai; N Ichimaru; M Abe; T Nishioka; H Miyoshi
        JOURNAL OF PESTICIDE SCIENCE, 2006, Peer-reviewed
      • Mass spectrometric analysis of the ubiquinol-binding site in cytochrome bd from Escherichia coli
        Y Matsumoto; M Murai; D Fujita; K Sakamoto; H Miyoshi; M Yoshida; T Mogi
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2006, Peer-reviewed
      • Synthesis of photolabile Delta lac-acetogenin for lphotoaffinity labeling of mitochondrial complex I
        M Murai; N Ichimaru; M Abe; T Nishioka; H Miyoshi
        JOURNAL OF PESTICIDE SCIENCE, 2006, Peer-reviewed
      • Dynamic function of the alkyl spacer of acetogenins in their inhibitory action with mitochondrial complex I (NADH-ubiquinone oxidoreductase)
        M Abe; M Murai; N Ichimaru; A Kenmochi; T Yoshida; A Kubo; Y Kimura; A Moroda; H Makabe; T Nishioka; H Miyoshi
        BIOCHEMISTRY, Nov. 2005, Peer-reviewed
      • Synthesis of non-THF analogs of acetogenin toward simplified mimics
        D Fujita; N Ichimaru; M Abe; M Murai; T Hamada; T Nishioka; H Miyoshi
        TETRAHEDRON LETTERS, Aug. 2005, Peer-reviewed
      • Synthesis of (4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin
        H Makabe; M Higuchi; H Konno; M Murai; H Miyoshi
        TETRAHEDRON LETTERS, Jul. 2005, Peer-reviewed
      • Synthesis and inhibition mechanism of Delta lac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I
        N Ichimaru; M Murai; M Abe; T Hamada; Y Yamada; S Makino; T Nishioka; H Makabe; A Makino; T Kobayashi; H Miyoshi
        BIOCHEMISTRY, Jan. 2005, Peer-reviewed
      • Synthesis and inhibition mechanism of Delta lac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I
        N Ichimaru; M Murai; M Abe; T Hamada; Y Yamada; S Makino; T Nishioka; H Makabe; A Makino; T Kobayashi; H Miyoshi
        BIOCHEMISTRY, Jan. 2005, Peer-reviewed
      • The side chain of ubiquinone plays a critical role in Na+ translocation by the NADH-ubiquinone oxidoreductase (Na+-NQR) from Vibrio cholerae
        Moe Ishikawa; Takahiro Masuya; Seina Kuroda; Shinpei Uno; Nicole L. Butler; Sara Foreman; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        Biochimica et Biophysica Acta (BBA) - Bioenergetics, Mar. 2022, Peer-reviewed

      Misc.

      • ミトコンドリア複合体‐I阻害剤としてのアミロライド類の作用機構研究
        MURAI MASATOSHI; MURAKAMI SONOMI; ITO TAKESHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 18 Mar. 2015
      • ミトコンドリア複合体‐Iのピンポイント化学修飾
        MASUYA TAKAHIRO; MURAI MASATOSHI; MORISAKA HIRONOBU; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 18 Mar. 2015
      • 出芽酵母ミトコンドリアVDACにおけるユビキノン結合部位の同定
        OKUDA AYAKA; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2015
      • アミロライド類縁体のミトコンドリア複合体‐Iにおける結合部位の同定
        ITO TAKESHI; MURAI MASATOSHI; MORISAKA HIRONOBU; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2015
      • 新規eptaibol化合物であるFKI‐6324Aは害虫AAC遺伝子組換え酵母の増殖を抑制する
        SUGA TAKUYA; ASAMI YUKIHIRO; HASHIMOTO SHOHEI; IWATSUKI MASATO; NONAKA KEN'ICHI; NAKASHIMA TAKUJI; WATANABE YOSHIHIRO; MATSUMOTO ATSUKO; SUGAWARA RYOHEI; SHIOTSUKI TAKAHIRO; YAMAMOTO TAKENORI; SHINOHARA YASUO; ICHIMARU NAOYA; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2015
      • ミトコンドリア複合体‐Iのピンポイント化学修飾
        MASUYA TAKAHIRO; MURAI MASATOSHI; MORISAKA HIRONOBU; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2015
      • コレラ菌ナトリウム輸送型NADH‐ユビキノン酸化還元酵素(Na+‐NQR)におけるユビキノン結合部位の同定
        NINOKURA SATOSHI; MURAI MASATOSHI; BARQUERA BLANCA; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2015
      • ミトコンドリア複合体‐Iのピンポイント化学修飾
        MASUYA TAKAHIRO; MURAI MASATOSHI; MORISAKA HIRONOBU; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 11 Dec. 2014
      • ミトコンドリア複合体‐Iのメカニズム解明に向けた特異的化学修飾
        MIYOSHI HIDETO; MASUTANI TAKAHIRO; MURAI MASATOSHI
        生体膜と薬物の相互作用シンポジウム講演要旨集, 20 Nov. 2014
      • コエンザイムQ結合タンパク質Coq10の解析
        KAWAMUKAI MAKOTO; SAI TOSHITADA; KAINO TOMOHIRO; MURAI MASATOSHI; MIYOSHI HIDETO
        イソプレノイド研究会例会講演要旨集, 12 Sep. 2014
      • ミトコンドリア複合体‐Iの位置特異的化学修飾
        MASUYA TAKAHIRO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 13 Mar. 2014
      • ミトコンドリア複合体‐I阻害剤としてのアミロライド類縁体の合成と作用機構の解明
        MURAKAMI SONOMI; ITO TAKESHI; HABU SAYAKO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 13 Mar. 2014
      • ミトコンドリアNADH‐ユビキノン酸化還元酵素(複合体‐I)の部位特異的化学修飾
        MASUYA TAKAHIRO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2014
      • キナゾリンのミトコンドリアADP/ATP輸送体における結合部位の同定
        ASANO SHU; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2014
      • ユビキノン結合性タンパク質Coq10におけるキノン結合部位の同定
        MATSUNOBU KOHEI; MURAI MASATOSHI; KAWAMUKAI MAKOTO; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2014
      • 病害虫ミトコンドリアに作用する天然物リガンドの探索
        ASAMI YUKIHIRO; MORI MIHOKO; SUGA TAKUYA; IWATSUKI MASATO; NAKASHIMA TAKUJI; HASHIMOTO SHOHEI; NONAKA KEN'ICHI; MATSUMOTO ATSUKO; YUGE HIDETAKA; MASUMA ROKURO; TAKAHASHI YOKO; SUGAHARA RYOHEI; SHIOTSUKI TAKAHIRO; YAMAMOTO TAKENORI; SHINOHARA YASUO; ICHIMARU NAOYA; MURAI MASATOSHI; MIYOSHI HIDETO; OMURA SATOSHI; SHIOMI KAZURO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2014
      • 合成ユビキノンプローブを用いたミトコンドリアタンパク質Coq10の解析
        MURAI MASATOSHI; MATSUNOBU KOHEI; KAWAMUKAI MAKOTO; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 18 Dec. 2013
      • ユビキノンプローブの合成とユビキノン結合性タンパク質Coq10の解析
        MURAI MASATOSHI; MATSUNOBU KOHEI; KUDO SAWAKO; KAWAMUKAI MAKOTO; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 05 Sep. 2013
      • キナゾリン型阻害剤を用いたミトコンドリアNADH‐ユビキノン酸化還元酵素(複合体‐I)のドメイン間相互作用の解明
        MURAI MASATOSHI; MASHIMO YUKO; HIRST JUDY; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 14 Mar. 2013
      • ユビキノンプローブの合成とユビキノン結合性タンパク質Coq10の解析
        MATSUNOBU KOHEI; MURAI MASATOSHI; KUDO SAWAKO; KAWAMUKAI MAKOTO; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2013
      • ミトコンドリア複合体‐Iに作用する光反応性フェンピロキシメートの結合部位の同定
        MURAI MASATOSHI; SHIRAISHI YUSUKE; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2013
      • ミトコンドリア複合体‐I阻害剤としてのアミロライド類縁体の合成と作用機構
        HABU SAYAKO; MURAKAMI SONOMI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2013
      • ミトコンドリア複合体‐Iに作用するキナゾリン型阻害剤の結合部位の同定
        ASANO SHU; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2013
      • Characterization of the inhibitor-binding site in mitochondrial NADH-Ubiquinone oxidoreductase (complex I) using fenpyroximate analogues
        M. Murai; Y. Shiraishi; N. Sakiyama; H. Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Oct. 2012
      • ミトコンドリア複合体‐Iの阻害剤結合部位の同定(2):結合部位の概観
        MURAI MASATOSHI; SHIRAISHI YUSUKE; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 14 Mar. 2012
      • ミトコンドリア複合体‐Iの阻害剤結合部位の同定(1):フェンピロキシメートの結合部位
        SHIRAISHI YUSUKE; MURAI MASATOSHI; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 14 Mar. 2012
      • ミトコンドリア複合体‐Iにおけるアセトゲニン結合部位の同定
        NAKANISHI SAYO; ABE MASATO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2012
      • ユビキノンプローブの創製と出芽酵母におけるユビキノン結合性タンパク質のスクリーニング
        KUDO SAWAKO; MURAI MASATOSHI; YAZAKI KAZUFUMI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集(Web), 05 Mar. 2012
      • ミトコンドリア複合体‐Iの阻害剤結合部位の同定
        MURAI MASATOSHI; SHIRAISHI YUSUKE; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2012
      • 機能性ユビキノンプローブの合成と結合タンパク質の同定
        DOI SAYAKO; MURAI MASATOSHI; YOKOYAMA MINORU; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 01 Oct. 2011
      • カルジオリピン類の合成によるシトクロムcとの分子間相互作用の解析
        SHIMBAYASHI RYOTA; KOBORI SHIN'YA; MORIYAMA IKUKO; ABE MASATO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2011
      • ミトコンドリア複合体‐Iにおけるアセトゲニンの結合部位の同定
        NAKANISHI SAYO; ABE MASATO; YAMAMOTO SHUHEI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2011
      • 光親和性ユビキノンプローブの合成と標的タンパク質の解析
        HABU SAYAKO; YOKOYAMA MINORU; MURAI MASATOSHI; ABE MASATO; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2011
      • ミトコンドリア複合体‐Iに作用する光反応性フェンピロキシメートの結合部位の同定
        MURAI MASATOSHI; SAKIYAMA NAOTO; SHIRAISHI YUSUKE; ABE MASATO; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2011
      • ミトコンドリア複合体‐Iに作用する光反応性フェンピロキシメートの結合部位の同定(I)
        MURAI MASATOSHI; SAKIYAMA NAOTO; SHIRAISHI YUSUKE; ABE MASATO; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 25 Feb. 2011
      • ミトコンドリア複合体‐Iに作用する光反応性フェンピロキシメートの結合部位の同定(II)
        SAKIYAMA NAOTO; MURAI MASATOSHI; SHIRAISHI YUSUKE; ABE MASATO; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 25 Feb. 2011
      • 光反応性アセトゲニンの合成と作用機構研究
        ABE MASATO; NAKANISHI SAYO; YAMAMOTO SHUHEI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 25 Feb. 2011
      • 機能性ユビキノンプローブの合成とユビキノン結合性タンパク質の探索
        YOKOYAMA MINORU; HABU SAYAKO; MURAI MASATOSHI; ABE MASATO; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 2011
      • キナゾリン型阻害剤を用いたミトコンドリアNADH‐ユビキノン酸化還元酵素(複合体‐I)のドメイン間相互作用の解明
        MURAI MASATOSHI; MASHIMO YUKO; HIRST JUDY; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2011
      • ミトコンドリア複合体‐Iに作用する光反応性フェンピロキシメートの結合部位の同定
        SHIRAISHI YUSUKE; MURAI MASATOSHI; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2011
      • 酵母Type II NADH脱水素酵素(NDH‐2)において活性酸素の生成が負に制御される分子機構の解析
        YAMASHITA TETSUO; YANG YU; OGISO(NAKAMARU) EIKO; HASHIMOTO TAKESHI; MURAI MASATOSHI; MIYOSHI HIDETO; IGARASHI JUNSUKE; YAGI(MATSUNO) AKEMI; YAGI TAKAO; KOSAKA HIROAKI
        日本生体エネルギー研究会討論会講演要旨集, 2011
      • 酵母シングルサブユニット・NADH‐キノン酸化還元酵素(Ndi1)の反応機構:活性酸素の生成抑制機構の解析
        YAMASHITA TETSUO; YANG YU; NAKAMARU EIKO; HASHIMOTO TAKESHI; MURAI MASATOSHI; IGARASHI JUNSUKE; MIYOSHI HIDETO; YAGI AKEMI; YAGI TAKAO; KOSAKA HIROAKI
        生化学, 2011
      • 呼吸鎖酵素最後の秘境 複合体‐I(NADH‐ユビキノン酸化還元酵素)の構造と機能
        MURAI MASATOSHI; MIYOSHI HIDETO
        化学, 01 Jan. 2011
      • 光反応性アセトゲニンの合成と作用機構研究
        NAKANISHI SAYO; YAMAMOTO SHUHEI; ABE MASATO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 02 Oct. 2010
      • Characterization of the binding site of Delta lac-acetogenin in bovine mitochondrial complex I by photoaffinity labeling
        Masatoshi Murai; Nobuyuki Kakutani; Naoto Sakiyama; Hideto Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Jul. 2010
      • ミトコンドリア複合体‐I阻害剤Δlac‐アセトゲニンの結合部位の同定
        MURAI MASATOSHI; KAKUTANI NOBUYUKI; SAKIYAMA NAOTO; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 21 Apr. 2010
      • 光反応性アセトゲニンの合成と作用機構研究
        ABE MASATO; YAMAMOTO SHUHEI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 21 Apr. 2010
      • 広汎なカルジオリピン類の有機合成と生理活性評価
        ABE MASATO; OYAMA SHUNJI; KOBORI SHIN'YA; MORIYAMA IKUKO; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2010
      • ミトコンドリア複合体‐I阻害剤Δlac‐アセトゲニンの結合部位の同定
        MURAI MASATOSHI; SUMIYA SHINJI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2010
      • ミトコンドリア複合体‐I阻害剤Δlac‐アセトゲニンの結合部位の同定
        SUMIYA SHINJI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 2010
      • 酵母の非プロトン輸送性NADH‐ユビキノン酸化還元酵素(Ndi1)のユビキノン結合部位の解明
        MASHIMO YUKO; MURAI MASATOSHI; YAMASHITA TETSUO; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2010
      • ミトコンドリア複合体‐I阻害剤Δlac‐アセトゲニンの結合部位の解明
        MURAI MASATOSHI; KAKUTANI NOBUYUKI; SAKIYAMA NAOTO; ABE MASATO; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2010
      • ミトコンドリア複合体‐Iに作用する光反応性アセトゲニンの合成と結合部位の解析
        MURAI MASATOSHI; SEKIGUCHI KOJI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2009
      • 光親和性標識法によるミトコンドリア複合体‐I阻害剤キナゾリンの結合部位の解析
        SEKIGUCHI KOJI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2009
      • 光親和性標識法によるミトコンドリア複合体‐I阻害剤キナゾリンの結合部位の解析
        SEKIGUCHI KOJI; MURAI MASATOSHI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 27 Feb. 2009
      • ミトコンドリア複合体‐Iに作用するアセトゲニンの結合部位の解析
        MURAI MASATOSHI; SEKIGUCHI KOJI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 27 Feb. 2009
      • Identification of the inhibitor binding SITE(S) in bovine complex-i by photoaffinity labeling
        Masatoshi Murai; Naoya Ichimaru; Takao Yagi; Hideto Miyoshi
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Jul. 2008
      • ミトコンドリア複合体‐I阻害剤の結合部位解明―光親和性標識実験によるアプローチ―
        MURAI MASATOSHI; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 11 Mar. 2008
      • ミトコンドリア複合体‐Iの新規阻害剤Δlac‐アセトゲニンの合成と作用機構研究
        ICHIMARU NAOYA; MURAI MASATOSHI; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農薬学会大会講演要旨集, 11 Mar. 2008
      • 光親和性標識法を用いたミトコンドリア複合体‐I阻害剤の結合部位の解析
        MURAI MASATOSHI; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2008
      • 光親和性標識法によるΔlac‐アセトゲニンの結合部位同定
        MURAI MASATOSHI; ICHIMARU NAOYA; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2007
      • ミトコンドリア複合体‐Iの新規阻害剤Δlac‐アセトゲニンの作用機構
        ICHIMARU NAOYA; MURAI MASATOSHI; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2007
      • ミトコンドリア複合体‐Iにおける阻害剤結合部位の解明
        MURAI MASATOSHI; ICHIMARU NAOYA; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本生体エネルギー研究会討論会講演要旨集, 2007
      • Δ‐lacアセトゲニンの複合体‐Iに対する作用機構研究
        MURAI MASATOSHI; ICHIMARU NAOYA; ABE MASAHITO; NISHIOKA TAKAAKI; MIYOSHI HIDEHITO
        日本農芸化学会大会講演要旨集, 05 Mar. 2006
      • 新規アセトゲニンmimics(Δlac‐アセトゲニン)の合成と作用機構研究
        ICHIMARU NAOYA; MURAI MASATOSHI; ABE MASAHITO; SENO MAI; MAKABE HIDEFUMI; NISHIOKA TAKAAKI; MIYOSHI HIDEHITO
        日本農芸化学会大会講演要旨集, 05 Mar. 2006
      • ミトコンドリア複合体‐I阻害剤アセトゲニン類の阻害機構研究:スペーサー部の機能
        ABE MASAHITO; MURAI MASATOSHI; ICHIMARU NAOYA; YOSHIDA TAKEHIKO; KUBO AKINA; NISHIOKA TAKAAKI; MIYOSHI HIDEHITO
        日本農芸化学会大会講演要旨集, 05 Mar. 2006
      • ミトコンドリア複合体‐Iの新規阻害剤Δlac‐アセトゲニンの開発
        MURAI MASATOSHI; ICHIMARU NAOYA; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農芸化学会関西支部講演会講演要旨集, 2006
      • バンレイシ科アセトゲニンrollicosin,murisolinの合成研究
        HATTORI YASUNAO; KIMURA YUKA; MORODA AKI; HIGUCHI MASAHARU; KONNO HIROYUKI; MURAI MASATOSHI; MIYOSHI HIDETO; MAKABE HIDEFUMI
        天然有機化合物討論会講演要旨集, 15 Sep. 2005
      • Δlac‐アセトゲニン類の合成と作用機構研究
        ICHIMARU NAOYA; MURAI MASATOSHI; ABE MASATO; HAMADA TSUYOSHI; MAKINO SAE; MAKABE HIDEFUMI; NISHIOKA TAKAAKI; MIYOSHI HIDETO
        日本農芸化学会大会講演要旨集, 05 Mar. 2005
      • ミトコンドリア複合体‐I阻害剤アセトゲニンの阻害機構研究:スペーサー部の機能
        ABE MASATO; MURAI MASATOSHI; ICHIMARU NAOYA; YOSHIDA TAKEHIKO; NISHIOKA TAKAAKI; MIYOSHI HIDEHITO
        日本農芸化学会関西支部講演会講演要旨集, 2005
      • 新規アセトゲニンmimics(Δlac‐アセトゲニン)の合成と作用機構研究
        ICHIMARU NAOYA; MURAI MASATOSHI; ABE MASATO; HAMADA TAKESHI; MAKINO SAE; MAKABE HIDEFUMI; NISHIOKA TAKAAKI; MIYOSHI HIDEHITO
        日本農芸化学会関西支部講演会講演要旨集, 2005

      Presentations

      • The side chain regulates diverse reaction manners of artificial ubiquinones in mitochondrial respiratory complex I
        Shinpei Uno; Ryo Ikunishi; Takahiro Masuya; Kyoko Shinzawa-Itoh; Masatoshi Murai; Hideto Miyoshi
        Japan Bioenergetics Group 47th meetinh, 17 Dec. 2021
      • Comprehensive understanding of multiple actions of anticancer drug tamoxifen in isolated mitochondria
        Yufu Unten; Masatoshi Murai; Tomoki Koshitaka; Kotaro Kitao; Osamu Shirai; Takahiro Masuya; Hideto Miyoshi
        Japan Bioenergetics Group 47th meeting, 17 Dec. 2021
      • The side chain of ubiquinone plays a critical role in Na+ translocation by NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Ishikawa M; Masuya T; Kuroda S; Uno S; Shiba T; Inaoka DK; Murai M; Barquera B; Miyoshi H
        Japan Bioenergetics Group 47th meeting, 17 Dec. 2021
      • Inhibition mechanism of manassantin as an inhibitor of mitochondrial respiratory complex I
        Nagaoka C; Murai M; Masuya T; Miyoshi H
        The 2021 annual meeting of JSBBA, 20 Mar. 2021
      • Mode of action study of fusaramin, a natural tetramic acid derivative targeting Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Sakai K; Asami Y; Masuya T; Miyoshi H
        The 2021 annal meeting of JSBBA, 20 Mar. 2021
      • IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism
        Murai M; Tsuji A; Akao T; Masuya T; Miyoshi H
        The 2021 annual meeting of JSBBA, 20 Mar. 2021
      • Pinpoint chemical labeling of the NqrB subunit in Vibrio cholerae Na+-pumping NADH-quinone oxidoreductase
        Ishikawa M; Tanaka H; Masuya T; Barquera B; Murai M; Miyoshi H
        The 2021 annal meeting of JSBBA, 20 Mar. 2021
      • Site-specific chemical cross-linking for elucidating the ubiquinone reaction site in mitochondrial complex I
        Masuya T; Uno S; Murai M; Miyoshi H
        The 2021 annual meeting of JSBBA, 20 Mar. 2021
      • Exploring the quinone-binding pocket in mitochondrial respiratory complex I using synthetic quinones as molecular probes
        Uno S; Masuya T; Shinzawa-Ito K; Shiba T; Inaoka DK; Murai M; Miyoshi H
        The 2021 Annual Meeting of JSBBA, 20 Mar. 2021
      • Exploring the quinone-binding pocket in mitochondrial respiratory complex I using synthetic quinones as molecular probes
        Uno S; Masuya T; Shinzawa-Ito K; Shiba T; Inaoka DK; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 46th annual meeting, 10 Mar. 2021
      • Specific chemical modification of the NqrB subunit in Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Ishikawa M; Masuya T; Tanaka H; Murai M; Barquera B; Miyoshi H
        Pesticide Science Society of Japan, 46th annual meeting, 09 Mar. 2021
      • Site-specific chemical cross-linking for elucidating the ubiquinone reaction site in mitochondrial complex I
        Masuya T; Uno S; Murai M; Miyoshi H
        Japan Bioenergetics Group 46th meeting, 11 Dec. 2020
      • Inhibition mechanism of mitochondrial respiratory complex I by IACS-010759, a candidate compound of anticancer agent
        Tsuji A; Akao T; Masuya T; Murai M; Miyoshi H
        JSBBA, 2020 annual meeting, 28 Mar. 2020
      • Site-specific chemical modification of Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        石川 萌; 桝谷 貴洋; 村井 正俊; Blanca Barquera; 三芳 秀人
        JSBBA, 2020 annual meeting, 28 Mar. 2020
      • Identification of the inhibitor-binding site in Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Sano Y; Masuya T; Murai M; Barquera B; Miyoshi H
        JSBBA, 2020 annual meeting, 28 Mar. 2020
      • Exploring the quinone-binding pocket in mitochondrial respiratory complex I using synthetic quinones as molecular probes
        Uno S; Masuya T; Shinzawa-Ito K; Shiba T; Inaoka DK; Murai M; Miyoshi H
        JSBBA, 2020 annual meeting, 26 Mar. 2020
      • Exploring the quinone-binding pocket in mitochondrial respiratory complex I using synthetic quinones as molecular probes
        Uno S; Masuya T; Shinzawa-Ito K; Shiba T; Inaoka DK; Murai M; Miyoshi H
        日本農薬学会第45回大会(コロナウイルス感染拡大により中止), 09 Mar. 2020
      • Inhibition mechanism of mitochondrial respiratory complex I by IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells
        Tsuji A; Akao T; Masuya T; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 45th annual meeting, 09 Mar. 2020
      • Identification of the korormicin-binding site in Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Masuya T; Sano Y; Tanaka H; Ito T; Barquera B; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 45th annual meeting, 09 Mar. 2020
      • Defining the mechanism of action of S1QELs, specific suppressors of superoxide production in the quinone-binding site in mitochondrial complex I
        Murai M; Banba A; Tsuji A; Miyoshi H
        Japan Bioenergetics Group 45th meeting, 22 Dec. 2019
      • Mode of action study of pentanediol-type compounds, specific inhibitors of VDAC1 in Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Yamamoto T; Shinohara Y; Ichimaru N; Miyoshi H
        Japan Bioenergetics Group 45th meeting, 21 Dec. 2019
      • Oversized ubiquinone as a molecular probe for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I
        Uno S; Masuya T; Shinzawa-Ito K; Shiba T; Inaoka D. K; Murai M; Miyoshi H
        Japan Bioenergetics Group 45th meeting, 21 Dec. 2019
      • Mode of action study of pentanediol-type compounds, specific inhibitors of VDAC1 in Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Yamatomo T; Ichimaru N; Shinohara Y; Miyoshi H
        JSBBA Kansai-Chubu 2019 annual meeting, 22 Sep. 2019
      • Exploring the structure and function of mitochondrial respiratory complex I through chemical biology approaches
        Masatoshi Murai
        JSBBA-Kansai 508th meeting, 01 Jun. 2019, Invited
      • Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I using synthetic quinones and inhibitors
        Uno S; Kimura H; Murai M; Miyoshi H
        JSBBA-Kansai 508th meeting, 01 Jun. 2019
      • Action manner of S1QELs, specific suppressors of superoxide production from mitochondrial respiratory complex I
        Banba A; Tsuji A; Murai M; Miyoshi H
        JSBBA, the 2019 annual meeting, 26 Mar. 2019
      • Identification of the binding site of amilorides in respiratory complex I
        Kimura H; Murai M; Miyoshi H
        JSBBA, the 2019 annual meeting, 26 Mar. 2019
      • Pentenediol-type compounds specifically inhibit mitochondrial VDAC1 in Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Ichimaru N; Yamamoto T; Shinohara Y; Miyoshi H
        JSBBA, the 2019 annual meeting, 26 Mar. 2019
      • Exploring the quinone binding pocket in respiratory complex I using synthetic quinone analogues
        Uno S; Murai M; Miyoshi H
        JSBBA, the 2019 annual meeting, 26 Mar. 2019
      • Mechanism of aggregation of mitochondrial ADP/ATP carrier induced by epoxycyclohexenedione-type compounds
        Aoyama A; Murai M; Miyoshi H
        JSBBA, the 2019 annual meeting, 26 Mar. 2019
      • Action manner of S1QELs, specific suppressors of superoxide production from mitochondrial respiratory complex I
        Banba A; Tsuji A; Kimura H; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 44th annual meeting, 12 Mar. 2019
      • Exploring the quinone/inhibitor-binding pocket in mitochondrial respiratory complex I
        Uno S; Kimura H; Murai M; Miyoshi H
        Pesticide Society of Japan, 44th meeting, 12 Mar. 2019
      • ミトコンドリア呼吸鎖複合体-Iの機能解明を目指した生物有機化学的研究:低分子化合物で紐解く巨大タンパク質の構造と機能
        Masatoshi Murai
        有機化学研究会(白鷺セミナー)第84回講演会, 11 Dec. 2018
      • Exploring the quinone/inhibitor-binding pocket in complex I by chemical biology approaches
        Murai M; Uno S; Kimura H; Miyoshi H
        Japan Bioenergetics Group 44th meeting, 08 Dec. 2018
      • Characterization of the quinone-binding pocket of mitochondrial respiratory complex I through specific chemical modifications
        Murai M; Masuya T; Miyoshi H
        19th European Bioenergetics Conference (EBEC2018), 25 Aug. 2018
      • Epoxycyclohexenedione-type compounds make up a new class of inhibitors of the bovine mitochondrial ADP/ATP carrierEpoxycyclohexenedione-type Compounds Make Up a New Class of Inhibitors of the Bovine Mitochondrial ADP/ATP Carrier
        Aoyama A; Murai M; Miyoshi, H
        19th European Bioenergetics Conference (EBEC2018), 25 Aug. 2018
      • Epoxycyclohexenedione-Type Compounds Make Up a New Class of Inhibitors of the Bovine Mitochondrial ADP/ATP Carrier
        Aoyama A; Murai M; Ichimaru N; Miyoshi H
        Pesticide Science Society of Japan, 43th annual meeting, 27 May 2018
      • Characterization of quinone-binding pocket of respiratory complex I through chemical modifications
        Murai M; Masuya T; Miyoshi H
        Pesticide Science Society of Japan, 43th annual meeting, 27 May 2018
      • Mode of action study of pentenediol derivatives against VDAC in Saccharomyces cerevisiae mitochondria
        Unten Y; Murai M; Ichimaru N; Yamamoto T; Shinohara Y; Miyoshi H
        JSBBA Annual Meeting 2018, 17 Mar. 2018
      • Identification of the binding site of amilorides in respiratory complex I
        Kimura H; Murai M; Miyoshi H
        JSBBA Annual Meeting 2018, 17 Mar. 2018
      • Mechanism of the inhibition of mitochondrial ADP/ATP carrier by epoxycyclohexenedione-type compounds
        Aoyama A; Murai M; Ichimaru N; Miyoshi H
        JSBBA Annual Meeting 2018, 17 Mar. 2018
      • Identification of the inhibitor binding site in the Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Ito T; Murai M; Ninokura S; Kitazumi Y; Barquera B; Miyoshi H
        JSBBA Annual Meeting 2018, 17 Mar. 2018
      • Pinpoint chemical modification of the quinone-access channel of respiratory complex I
        Murai M; Masuya T; Miyoshi H
        Japan Bioenergetics Group 43th meeting, 21 Dec. 2017
      • Identification of the inhibitor binding site in the Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Ito T; Murai M; Ninokura S; Kitazumi Y; Barquera B; Miyoshi H
        Japan Bioenergetics Group 43th meeting, 21 Dec. 2017
      • Pinpoint chemical modification of the quinone-access channel of mitochondrial complex I via a two-step conjugation reaction
        Murai M; Masuya T; Miyoshi H
        JSBBA-Kansai-Annual Meeting, 22 Sep. 2017
      • Mechanism of the inhibition of bovine heart mitochondrial ADP/ATP carrier by epoxycyclohexenedione-type inhibitors
        Aoyama A; Murai M; Miyoshi H
        JSBBA-Kansai-Annual Meeting, 22 Sep. 2017
      • Identification of the inhibitor binding site in Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae
        Ito T; Murai M; Barquera B; Miyoshi H
        JSBBA-Kansai-annunal meeting, 22 Sep. 2017
      • Characterization of the ubiquinone-binding pocket of respiratory complex I through chemical modifications
        Masatoshi Murai
        The 2017 Gordon Research Conference on Bioenergetics, 07 Jun. 2017, Invited
      • Synthetic ubiquinones specifically bind to mitochondrial voltage-dependent anion channel (VDAC) in Saccharomyces cerevisiae mitochondria
        Murai M; Okuda A; Yamamoto T; Shinohara Y; Miyoshi H
        JSBBA annual meeting 2017, 20 Mar. 2017
      • Isolation and total synthesis of korormicin, a potent inhibitor of sodium-translocating NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Ito T; Tosaki T; Murai M; Barquera B; Miyoshi H
        JSBBA annual meeting 2017, 20 Mar. 2017
      • Site-specific chemical modification of mitochondrial respiratory complex I
        Masuya T; Murai M; Miyoshi H
        JSBBA annual meeting 2017, 20 Mar. 2017
      • Specific methylation of the ubiquinone binding cavity of bovine mitochondrial complex I via ligand-directed tosyl chemistry
        Masuya T; Inaoka H; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 42th meeting, 08 Mar. 2017
      • Synthetic ubiquinones specifically bind to mitochondrial voltage-dependent anion channel1 (VDAC) in Saccharomyces cerevisiae
        Murai M; Okuda A; Yamamoto T; Shinohara Y; Miyoshi H
        Pesticide Science Society of Japan, 42th meeting, 08 Mar. 2017
      • Isolation and total synthesis of korormicin, an inhibitor of sodium-translocating NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Ito T; Tosaki T; Murai M; Barquera B; Miyoshi H
        Pesticide Science Society of Japan, 42th meeting, 08 Mar. 2017
      • Reduction of synthetic ubiquinone QT catalyzed by mitochondrial respiratory complex I is decoupled from proton translocation
        Murai M; Okuda K; Masuya T; Miyoshi H
        Japan Bioenergetics Group 42th meeting, 19 Dec. 2016
      • Site-specific chemical modification of mitochondrial respiratory complex I
        Masuya T; Murai M; Inaoka H; Miyoshi H
        Japan Bioenergetics Group 42th meeting, 19 Dec. 2016
      • Identification of the binding site of amilorides in mitochondrial respiratory complex I
        Ito T; Murai M; Miyoshi H
        18th European Bioenergetics Conference (EBEC2016), 02 Jul. 2016
      • Synthetic ubiquinones specifically bind to mitochondrial voltage-dependent anion channel of Saccharomyces cerevisiae
        Murai M; Okuda A; Yamamoto T; Shinohara Y; Miyoshi H
        18th European Bioenergetics Conference (EBEC2016), 02 Jul. 2016
      • Site-specific chemical modifications of the quinone binding cavity of bovine heart mitochondrial complex I
        TMasuya T; Murai M; Inaoka H; Miyoshi H
        18th European Bioenergetics Conference (EBEC2016), 02 Jul. 2016
      • Reduction of synthetic ubiquinone QT catalyzed by bovine mitochondrial complex I is decoupled with proton translocation
        Okuda K; Murai M; Aburaya S; Aoki W; Miyoshi H
        JSBBA annual meeting 2016, 29 Mar. 2016
      • Specific methylation of ubiquinone-binding pocket in mitochondrial complex I through Tosyl chemistry
        Inaoka H; Murai M; Masuya T; Aburaya S; Aoki W; Miyoshi H
        JSBBA annual meeting 2016, 29 Mar. 2016
      • Mitochondrial voltage dependent anion channel of Saccharomyces cerevisiae specifically accommodates ubiquinone
        Okuda A; Murai M; Yamamoto T; Shinohara Y; Miyoshi H
        JSBBA annual meeting 2016, 29 Mar. 2016
      • Reduction of synthetic ubiquinone QT catalyzed by bovine mitochondrial complex I is decoupled from proton translocation
        Masuya T; Okuda K; Murai M; Miyoshi H
        Pesticide Science Society of Japan, 41th meeting, 19 Mar. 2016
      • Characterization of amilorides as potent inhibitors of mitochondrial respiratory complex I
        Ito T; Murai M; Murakami S; Morisaka H; Miyoshi H
        Pesticide Science Society of Japan, 41th meeting, 19 Mar. 2016
      • Action mechanism of mitochondrial respiratory complex I inhibitors
        Miyoshi H; Murai M
        Pesticide Science Society of Japan, 41th meeting (Symposium), 18 Mar. 2016, Invited
      • Characterization of the ubiquinone-binding protein Coq10 using a synthetic ubiquinone probe
        Murai M; Miyoshi H
        Pesticide Science Society of Japan 41th meeting (Symposium), 18 Mar. 2016, Invited
      • Pinpoint chemical modification of mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Masuya T; Murai M; Morisaka H; Miyoshi H
        30th Meeting of committee on pesticide design, 12 Nov. 2015
      • Identification of the binding site of amilorides in mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Ito T; Murai M; Murakami M; Morisaka H; Miyoshi H
        30th Meeting of commettee on pesticide design, 12 Nov. 2015
      • Amilorides bind to the quinone binding pocket of bovine mitochondrial complex I
        Murai M; Miyoshi H
        Gordon Research Conference on Bioenergetics, 21 Jun. 2015
      • Pinpoint chemical modification of mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Masuya T; Murai M; Morisaka H; Miyoshi H
        JSBBA annual meeting 2015, 27 Mar. 2015
      • Identification of the binding site of amilorides in mitochondrial complex I
        Ito T; Murai M; Morisaka H; Miyoshi H
        JSBBA annual meeting 2015, 27 Mar. 2015
      • Identification of the ubiquinone-binding site in Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Ninokura S; Murai M; Barquera B; Miyoshi H
        JSBBA annual meeting 2015, 27 Mar. 2015
      • Characterization of the ubiquinone-binding site in yeast mitochondrial voltage dependent anion channnel
        Okuda A; Murai M; Miyoshi H
        JABBA annual meeting 2015, 27 Mar. 2015
      • Pinpoint chemical modification of mitochondrial complex I
        Takahiro Masuya; Masatoshi Murai; Hironobu Morisaka; Hideto Miyoshi
        Pesticide Science Society of Japan, 40th meeting, 20 Mar. 2015
      • Synthesis and characterization of amilorides as potent inhibitors of mitochondrial respiratory complex I
        Masatoshi Murai; Sonomi Murakami; Takeshi Ito; Hideto Miyoshi
        Pesticide Science Society of Japan 40th meeting, 20 Mar. 2015
      • Pinpoint chemical modification of mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Takahiro Masuya; Masatoshi Murai; Hironobu Morisaka; Hideto Miyoshi
        40th Japan Bioenergetics Group Meeting (JBEG2014), 13 Dec. 2014
      • Site-Specific Chemical Modification of Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I) Through Ligand-Directed Tosylate Chemistry
        Murai M; Masuya T; Morisaka H; Ifuku K; Miyoshi H
        18th European Bioenergetics Conference (EBEC2014), 12 Jul. 2014
      • Identification of the binding site of quinazoline in mitochondrial ADP/ATP carrier
        Shu Asano; Masatoshi Murai; Hideto Miyoshi
        JSBBA annual meeting 2014, 29 Mar. 2014
      • Site-specific chemical labeling of mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Takahiro Masuya; Masatoshi Murai; Hideto Miyoshi
        JSBBA annual meeting 2014, 29 Mar. 2014
      • Identification of ubiquinone binding site in mitochondrial Coq10 using a synthetic ubiquinone probe
        Kohei Matsunobu; Masatoshi Murai; Makoto Kawamukai; Hideto Miyoshi
        JSBBA annual meeting 2014, 29 Mar. 2014
      • Synthesis and characterization of amiloride derivatives as inhibitors of mitochondrial complex I
        Sonomi Murakami; Takeshi Ito; Sayako Habu; Masaoshi Murai; Hideto Miyoshi
        Pesticide Science Society of Japan 39th annual meeting, 14 Mar. 2014
      • Site-specific chemical labeling of mitochondrial complex )
        Takahiro Masuya; Masatoshi Murai; Hideto Miyoshi
        Pesticide Science Society of Japan 39th annual meeting, 14 Mar. 2014
      • Characterization of mitochondrial Coq10 using a synthetic ubiquinone probe
        Masatoshi Murai; Kohei Matsunobu; Makoto Kawamukai; Hideto Miyoshi
        39th Japan Bioenergetics Group meeting (JBEG2013), 19 Dec. 2013
      • Characterization of mitochondrial Coq10 using a synthetic ubiquinone probe
        Masatoshi Murai; Kohei Matsunobu; Sawako Kudo; Makoto Kawamukai; Hideto Miyoshi
        JSBBA Kansai-Nishinihon, joint meeting, 06 Sep. 2013
      • Characterization of the mitochondrial ubiquinone-binding protein Coq10 using a synthetic ubiquinone probe
        Masatoshi Murai; Kohei Matsunobu; Sawako Kudo; Makoto Kawamukai; Hideto Miyoshi
        Gordon Research Conference on Bioenergetics, Jun. 2013
      • Characterization of the mitochondrial ubiquinone-­‐binding protein Coq10 using a synthetic ubiquinone probe
        Kohei Matsunobu; Masatoshi Murai; Sawako Kudoh; Makoto Kawamukai; Hideto Miyoshi
        JSBBA Annual Meeting 2013, Mar. 2013
      • Synthesis and characterization of amiloride derivatives as inhibitors of mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Sayako Habu; Sonomi Murakami; Masatoshi Murai; Hideto Miyoshi
        JSBBA Annual Meeting 2013, Mar. 2013
      • Identificaon of the binding site of quinazoline-­type inhibitor of mitochondrial NADH-­ubiquinone oxidoreductase (complex I)
        Shu Asano; Masatoshi Murai; Hideto Miyoshi
        JSBBA Annual Meeting 2013, Mar. 2013
      • Characterization of the binding site of photolabile fenpyroximate analogues in bovine NADH-­‐ubiquinone oxidoreductase (complex I)
        Masatoshi Murai; Yusuke Shiraishi; Naoto Sakiyama; Hideto Miyoshi
        JSBBA Annual Meeting 2013, Mar. 2013
      • Exploring the interaction between 49 kDa and ND1 subunits in mitochondrial complex I using a quinazoline-type inhibitor
        Masatoshi Murai; Yuko Mashimo; Hideto Miyoshi
        Pesticide Society of Japan, 38th Annual Meeting, Mar. 2013
      • Identification of the inhibitor-binding site in bovine mitochondrial NADH-ubiquinone oxidoreductase (complex I)
        Masatoshi Murai; Yusuke Shiraishi; Naoto Sakiyama; Hideto Miyoshi
        38th Japan Bioenergetics Group Meeting (JBEG 2012), Dec. 2012
      • Characterization of the inhibitor-binding site in mitochondrial NADH-Ubiquinone oxidoreductase (Complex I) using fenpyroximate analogues
        Masatoshi Murai; Yusuke Shiraishi; Naoto Sakiyama; Hideto Miyoshi
        17th European Bioenergetics Conference (EBEC2012), Sep. 2012
      • Comprehensive survey of ubiquinone-binding protein in Saccaromyces serevisiae using synthetic molecular probes
        Sawako Kudo; Masatoshi Murai; Kazufumi Yazaki; Hideto Miyoshi
        JSBBA Annual Meeting 2012, Mar. 2012
      • Identification of the inhibitor binding site in mitochondrial complex I (1): the binding site of fenpyroximate.
        Yusuke Shiraishi; Masatoshi Murai; Naoto Sakiyama; Hideto Miyoshi
        Pesticide Society of Japan, 37th Annual Meeting, Mar. 2012
      • Identification of the inhibitor binding site in mitochondrial complex I (2): an overview of the site
        Masatoshi Murai; Yusuke Shiraishi; Naoto Sakiyama; Hideto Miyoshi
        Pesticide Society of Japan, 37th Annual Meeting, Mar. 2012
      • Characterization of the binding site of photolabile fenpyroximate analogues in bovine NADH-ubiquinone oxidoreductase (complex I)
        Yusuke Shiraishi; Masatoshi Murai; Naoto Sakiyama; Hideto Miyoshi
        37th Japan Bioenergetics Group Meeting (JBEG 2011), Dec. 2011
      • Exploring interactions between the 49 kDa and ND1 subunits in mitochondrial NADH-ubiquinone oxidoreductase (complex I) using a quinazoline-type inhibitor
        Masatoshi Murai; Yuko Mashimo; Hideto Miyoshi
        37th Japan Bioenergetics Group Meeting (JEBG 2011), Dec. 2011
      • Exploring interactions between the 49 kDa and ND1 subunits in mitochondrial NADH-ubiquinone oxidoreductase (complex I) by photoaffinity labeling
        Masatoshi Murai; Yuko Mashimo; Hideto Miyoshi
        Nouyaku Dezain Kenkyu-kai, Nov. 2011
      • Synthesis of functionalized-ubiquinone probe and identification of the ubiquinone-binding protein
        Sayako Habu; Masatoshi Murai; Minoru Yokoyama; Hideto Miyoshi
        JSBBA-Kansai and Chubu, Joint Meeting 2011, Oct. 2011
      • Synthesis of photolabile ubiquinone probes and identification of the ubiquinone-binding protein
        Sayako Habu; Minoru Yokoyama; Masatoshi Murai; Masato Abe; Hideto Miyoshi
        JSBBA Annual Meeting 2011, Mar. 2011
      • Synthesis of a photolabile fenpyroximate analogue and identification of its binding site in mitochondrial complex I
        Masatoshi Murai; Naoto Sakiyama; Yusuke Shiraishi; Masato Abe; Hideto Miyoshi
        JSBBA Annual Meeting 2011, Mar. 2011
      • Identification of the binding site of photolabile fenpyroximate analogue in bovine mitochondrial complex I (II)
        Naoto Sakiyama; Masatoshi Murai; Yusuke Shiraishi; Masato Abe; Hideto Miyoshi
        Pesticide Society of Japan, 36th Annual Meeting, Mar. 2011
      • Identification of the binding site of photolabile fenpyroximate analogue in bovine mitochondrial complex I (I)
        Masatoshi Murai; Naoto Sakiyama; Yusuke Shiraishi; Masato Abe; Hideto Miyoshi
        Pesticide Society of Japan 38th Annual Meeting, Mar. 2011
      • Synthesis of functionalized-ubiqinone probes for identification of the ubiquinone-binding protein
        Minoru Yokoyama; Sayako Habu; Masatoshi Murai; Masato Abe; Hideto Miyoshi
        JSBBA-Kansai 473th Meeting, Jan. 2011
      • Characterization of the ubiquinone binding site in the alternative NADH-quinone oxidoreductase of Saccharomyces cerevisiae by photoaffinity labeling
        Yuko Mashimo; Masatoshi Murai; Tetsuo Yamashita; Hideto Miyoshi
        36th Japan Bioenergetics Group Meeting (JBEG 2010), Nov. 2010
      • Identification of the binding site of Δlac-acetogenin in bovine mitochondrial complex I
        Masatoshi Murai; Nobuyuki Kakutani; Naoto Sakiyama; Masato Abe; Hideto Miyoshi
        36th Japan Bioenergetics Group Meeting (JBEG 2010), Nov. 2010
      • Identification and Characterization of the Binding Site of Δlac-Acetogenin in Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I) by Photoaffinity Labeling
        Masatoshi Murai; Nobuyuki Kakutani; Naoto Sakiyama; Hideto Miyoshi
        16th European Bioenergetics Conference (EBEC2010), Jun. 2010
      • Identification of the binding site of Δlac-acetogenin in bovine heart mitochondrial complex I
        Masatoshi Murai; Nobuyuki Kakutani; Naoto Sakiyama; Hideto Miyoshi
        Pesticide Society of Japan, 35th Annual Meeting, May 2010
      • Identification of the Binding-Site of Δlac-Acetogenin in Bovine Mitochondrial Complex I
        Masatoshi Murai; Nobuyuki Kakutani; Hideto Miyoshi
        JSBBA Annual Meeting 2010, Mar. 2010
      • Identification of the binding site of Δlac-acetogenin in bovine heart mitochondrial NADH-ubiquinone oxidoreductase
        Nobuyuki Kakutani; Masatoshi Murai; Hideto Miyoshi
        JSBBA-Kansai 463th Meeting, Feb. 2010
      • Identification of the inhibitor binding site in mitochondrial NADH-ubiquinone oxidoreductase using a quinazoline-type inhibitor
        Masatoshi Murai; Hideto Miyoshi
        Nouyaku Dezain Kenkyu-kai (in Japanese), Nov. 2009
      • Exploring the Inhibitor Binding Site in Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I) using Photoaffinity Labeling Probes
        Masatoshi Murai; Hideto Miyoshi
        The 11th International Kyoto Conference on New Aspects of Organic Chemistry, Nov. 2009
      • Exploring the Inhibitor Binding Site in Mitochondrial Complex I by Photoaffinity Labeling
        Masatoshi Murai; Hideto Miyoshi
        The 1st China-Japan-Korea Workshop on Pesticide Science, Oct. 2009
      • Synthesis of photoreactive acetogenin and identification of its binding site in mitochondrial complex I
        Masatoshi Murai; Koji Sekiguchi; Hideto Miyoshi
        JSBBA Annual Meeting 2009, Mar. 2009
      • Synthesis of photoreactive acetogenin and identification of its binding site in mitochondrial complex I
        Masatoshi Murai; Koji Sekiguchi; Hideto Miyoshi
        Pesticide Society of Japan, 34th Annual Meeting, Mar. 2009
      • Characterization of inhibitor binding site in mitochondrial complex I using a quinazoline-type photoaffinity labeling probe
        Masatoshi Murai; Koji Sekiguchi; Hideto Miyoshi
        34th Japan Bioenergetics Group Meeting (JEBG 2008), Nov. 2008
      • Identification of the Inhibitor Binding Site(s) in Complex I by photoaffinity labeling
        Masatoshi Murai; Naoya Ichimaru; Takao Yagi; Hideto Miyoshi
        15th European Bioenergetics Conference (EBEC 2008), Jul. 2008
      • Probing the inhibitor binding site in mitochondrial complex I (NADH-ubiquinone oxidoreductase)
        Masatoshi Murai; Takaaki Nishioka; Hideto Miyoshi
        Pesticide Society of Japan, 33th Annual Meeting, Mar. 2008
      • Probing the Inhibitor Binding Site in Mitochondrial Complex I by Photoaffinity Labeling
        Masatoshi Murai; Takaaki Nishioka; Hideto Miyoshi
        JABBA Annual Meeting 2008, Mar. 2008
      • Mitochondrial complex I (NADH-Ubiquinone oxidoreductase); Probing the inhibitor binding site by photoaffinity labeling
        Masatoshi Murai; Naoya Ichimaru; Takaaki Nishioka; Hideto Miyoshi
        33th Japan Bioenergetics Group meeting (JEBG 2007), Nov. 2007
      • Identification of the binding site of Δlac-acetogenin by photoaffinity labeling
        Masatoshi Murai; Naoya Ichimaru; Takaaki Nishioka; Hideto Miyoshi
        JSBBA Annual Meeting 2007, Mar. 2007
      • Identification of the binding site of delta.lac acetogenin in mitochindrial complex I
        Masatoshi Murai; Takaaki Nishioka; Hideto Miyoshi
        JSBBA Annual Meeting 2007, Mar. 2007
      • Mode of inhibitory action of delta.lac-acetogenins, a new class of inhibitors of bovine heart mitochondrial complex I (NADH-ubiquinone oxidoreductase)
        Masatoshi Murai; Hideto Miyoshi
        32th Japan Bioenergetics Group Meeting (JBEG), Dec. 2006
      • Delta. lac acetogenin, a new class of inhibitors of bovine heart mitochondrial complex I
        Masatoshi Murai; Naoya Ichimaru; Takaaki Nishioka; Hideto Miyoshi
        JSBBA Kansai Annual Meeting 2006, Oct. 2006
      • Mode of inhibitory action of delta.lac-acetogenin on mitochondrial complex I
        Masatoshi Murai; Naoya Ichimaru; Masato Abe; Takaaki Nishioka; Hideto Miyoshi
        JSBBA Annual Meeting 2006, Mar. 2006
      • Screening of the proteins involved in uptake of ubiquinone in Saccharomyces cerevisiae using a synthetic ubiquinone probe
        Seina Kuroda; Masatoshi Murai; Takahiro Masuya; Masahide Oku; Hideto Miyoshi
        JSBBA 2022 annual meeting, 17 Mar. 2022
      • Comprehensive understanding of multiple actions of anticancer drug tamoxifen in isolated rat liver mitochondria
        Yufu Unten; Masatoshi Murai; Tomoki Koshitaka; Kotaro Kitao; Osamu Shirai; Takahiro Masuya; Hideto Miyoshi
        JSBBA annual meeting, 17 Mar. 2022
      • Site-specific chemical modification of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Hinako Tanaka; Moe Ishikawa; Takahiro Masuya; Wataru Aoki; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        JSBBA 2022 annual meeting, 17 Mar. 2022
      • Diverse reaction manners of artificial ubiquinones in mitochondrial respiratory complex I
        Shinpei Uno; Ryo Ikunishi; Takahiro Masuya; Kyoko Shinzawa-Ito; Masatoshi Murai; Hideto Miyoshi
        JSBBA annual meeting, 17 Mar. 2022
      • The side chain of ubiquinone plays a critical role in Na+ translocation by NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Moe Ishikawa; Takahiro Masuya; Seina kuroda; Shinpei Uno; Tomoo Shiba; Ken Daniel Inaoka; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        JSBBA 2022 annual meeting, 17 Mar. 2022
      • Dynamic structural properties of the ubiquinone reaction cavity of mitochondrial respiratory complex I
        Shinpei Uno; Ryo Ikunishi; Takahiro Masuya; Kyoko Shinzawa-Ito; Masatoshi Murai; Hideto Miyoshi
        Pesticide Science Society of Japan 47th annual meeting, 08 Mar. 2022
      • The side chain of ubiquinone plays a critical role in Na+ translocation by the NADH-ubiquinone oxidoreductase from Vibrio cholerae
        Moe Ishikawa; Takahiro Masuya; Seina Kuroda; Shinpei Uno; Tomoo Shiba; Masatoshi Murai; Blanca Barquera; Hideto Miyoshi
        Pesticide Science Society of Japan 47th annual meeting, 08 Mar. 2022

      Awards

      • Mar. 2019
        Japan Society for Bioscience, Biotechnology and Agrochemistry, JSBBA Award for Young Scientists

      External funds: Kakenhi

      • Mechanism of aggregation of ADP/ATP carrier induced by epoxycyclohexenedione (ECHD)-type inhibitor
        Grant-in-Aid for Scientific Research (C)
        Basic Section 38040:Bioorganic chemistry-related
        Kyoto University
        Masatoshi Murai
        From 01 Apr. 2018, To 31 Mar. 2021, Project Closed
        ミトコンドリア;ADP/ATP輸送体;ECHD類;ケミカルバイオロジー;阻害剤
      • Novel pathway of coenzyme Q biosynthesis
        Grant-in-Aid for Scientific Research (B)
        Shimane University
        Makoto Kawamukai
        From 01 Apr. 2017, To 31 Mar. 2021, Project Closed
        coenzyme Q;ubiquinone;S. pombe;fission yeast;PHB;PABA;isoprenoid;コエンザイムQ;ユビキノン;分裂酵母;coenzymeQ;mitochondria;S. pome;ミトコンドリア;電子伝達系;抗酸化;イソプレノド
      • Conversion of mitochondrial respiratory complex I to a light-driven proton pump by chemical modification
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Hideto Miyoshi
        From 01 Apr. 2016, To 31 Mar. 2018, Project Closed
        生物制御化学;ミトコンドリア呼吸鎖酵素;複合体-I;タンパク質化学修飾;ミトコンドリア;化学修飾;ミトコンドリア呼吸鎖;光スイッチ
      • Functional analysis of mitochondrial VDAC using synthetic ubiquinone probes
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        MASATOSHI MURAI
        From 01 Apr. 2015, To 31 Mar. 2018, Project Closed
        ユビキノン;ミトコンドリア;VDAC;光親和性標識;ケミカルバイオロジー;膜透過性亢進;クリックケミストリー
      • Site-specific modification of respiratory complex I for single molecule analysis
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Hideto Miyoshi
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        生物制御化学;呼吸鎖複合体-I;化学修飾;ユビキノン;ミトコンドリア呼吸鎖;トシル化学;複合体-I;ミトコンドリア;呼吸鎖;呼吸鎖酵素
      • Molecular mechanism of mitochondrial proteins using ubiquinone as a cofactor
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        Masatoshi MURAI
        From 01 Apr. 2013, To 31 Mar. 2015, Project Closed
        ユビキノン;Coq10;光親和性標識;ミトコンドリア;複合体-I;Click Chemistry;ユビキノン結合性タンパク質
      • Probing the intercellular traffic mechanism of ubiquinone using synthetic molecular probes
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        Masatoshi MURAI
        From 01 Apr. 2011, To 31 Mar. 2013, Project Closed
        ユビキノン;ミトコンドリア;光親和性標識;Click Chemistry;複合体-I;出芽酵母
      • Study on the function of ND1 subunit, a key subunit of respiratory complex I
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Hideto MIYOSHI
        From 01 Apr. 2011, To 31 Mar. 2014, Project Closed
        細胞機能調節物質;ミトコンドリア呼吸鎖酵素;複合体-I;アセトゲニン;光親和性標識;トシルケミストリー;ミトコンドリア;阻害剤;呼吸鎖複合体-I;ND1サブユニット;呼吸鎖阻害剤
      • Exploring the reaction mechanism of mitochondrial NADH-ubiquinone oxidoreductase (compelx I) using a specific inhibitor as a molecular probe
        Grant-in-Aid for Research Activity Start-up
        Kyoto University
        Masatoshi MURAI
        From 01 Apr. 2009, To 31 Mar. 2011, Project Closed
        ミトコンドリア;複合体-I;キナゾリン;ユビキノン;光親和性標識;アセトゲニン;生物有機化学
      • Screening of the proteins involved in uptake of ubiquinone in Saccharomyces cerevisiae using synthetic ubiquinone probes
        Grant-in-Aid for Scientific Research (B)
        Basic Section 38040:Bioorganic chemistry-related
        Kyoto University
        村井 正俊
        From 01 Apr. 2022, To 31 Mar. 2025, Granted
        ユビキノン;細胞内輸送;光親和性標識;クリックケミストリー;出芽酵母

      External funds: others

      • Generation of “Light-driven” respiratory complex I through chemical modification
        上原記念生命科学財団研究奨励金
        From 01 Apr. 2018, To 31 Mar. 2019
        村井正俊
      • Probing the structure and function of mitochondrial NADH-ubiquinone oxidoreductase (Complex I) by photoaffinity labeling technique
        上原記念生命科学財団 研究奨励金
        From 01 Apr. 2010, To 31 Mar. 2011
        村井正俊
      list
        Last Updated :2022/09/30

        Education

        Teaching subject(s)

        • From 01 Apr. 2022, To 31 Mar. 2023
          Introduction to Applied Life Science IV
          5607, Fall, Faculty of Agriculture, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course of Biofunction Chemistry2
          CC36, Year-long, Graduate School of Agriculture, 6
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course of Biofunction Chemistry1
          CC35, Year-long, Graduate School of Agriculture, 6
        • From 01 Apr. 2022, To 31 Mar. 2023
          Chemistry of Biological Activity
          CA19, Spring, Graduate School of Agriculture, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Laboratory Course in Organic Chemistry
          5677, Year-long, Faculty of Agriculture, 3
        • From 01 Apr. 2022, To 31 Mar. 2023
          Biofunction Chemistry Seminar2
          CB36, Year-long, Graduate School of Agriculture, 3
        • From 01 Apr. 2022, To 31 Mar. 2023
          Biofunction Chemistry Seminar1
          CB35, Year-long, Graduate School of Agriculture, 3
        • From Apr. 2011, To Mar. 2012
          有機化学実験
          Fall, 農学部
        • From Apr. 2011, To Mar. 2012
          生物機能制御化学専攻実験
          農学研究科
        • From Apr. 2011, To Mar. 2012
          生物機能制御化学専攻演習
          農学研究科
        • From Apr. 2012, To Mar. 2013
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2013, To Mar. 2014
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2013, To Mar. 2014
          Chemistry of Biological Activity
          Fall, 農学研究科
        • From Apr. 2013, To Mar. 2014
          Biofunction Chemistry Seminar
          Year-long, 農学研究科
        • From Apr. 2013, To Mar. 2014
          Experimental Course of Biofunction Chemistry
          Year-long, 農学研究科
        • From Apr. 2014, To Mar. 2015
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2014, To Mar. 2015
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2014, To Mar. 2015
          Biofunction Chemistry Seminar
          Year-long, 農学研究科
        • From Apr. 2014, To Mar. 2015
          Experimental Course of Biofunction Chemistry
          Year-long, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2015, To Mar. 2016
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Experimental Course of Biofunction Chemistry
          Year-long, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Biofunction Chemistry Seminar
          Year-long, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2015, To Mar. 2016
          Fundamental Study on Agrochemicals
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2016, To Mar. 2017
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Experimental Course of Biofunction Chemistry
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Biofunction Chemistry Seminar
          Year-long, 農学研究科
        • From Apr. 2016, To Mar. 2017
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2017, To Mar. 2018
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Experimental Course of Biofunction Chemistry
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Biofunction Chemistry Seminar
          Year-long, 農学研究科
        • From Apr. 2017, To Mar. 2018
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2018, To Mar. 2019
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2018, To Mar. 2019
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2018, To Mar. 2019
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2018, To Mar. 2019
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2018, To Mar. 2019
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2019, To Mar. 2020
          Introduction to Applied Life Science IV
          Fall, 農学部
        • From Apr. 2019, To Mar. 2020
          Laboratory Course in Organic Chemistry
          Fall, 農学部
        • From Apr. 2019, To Mar. 2020
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2019, To Mar. 2020
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2019, To Mar. 2020
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2019, To Mar. 2020
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2020, To Mar. 2021
          Scientific English
          Spring, 農学部
        • From Apr. 2020, To Mar. 2021
          Introduction to Applied Life Science IV
          Fall, 農学部
        • From Apr. 2020, To Mar. 2021
          Laboratory Course in Organic Chemistry
          Year-long, 農学部
        • From Apr. 2020, To Mar. 2021
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2020, To Mar. 2021
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2020, To Mar. 2021
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2020, To Mar. 2021
          Chemistry of Biological Activity
          Spring, 農学研究科
        • From Apr. 2021, To Mar. 2022
          Basic Organic Chemistry I
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Introduction to Applied Life Science IV
          Fall, 農学部
        • From Apr. 2021, To Mar. 2022
          Laboratory Course in Organic Chemistry
          Year-long, 農学部
        • From Apr. 2021, To Mar. 2022
          Experimental Course of Biofunction Chemistry1
          Year-long, 農学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course of Biofunction Chemistry2
          Year-long, 農学研究科
        • From Apr. 2021, To Mar. 2022
          Biofunction Chemistry Seminar1
          Year-long, 農学研究科
        • From Apr. 2021, To Mar. 2022
          Biofunction Chemistry Seminar2
          Year-long, 農学研究科
        • From Apr. 2021, To Mar. 2022
          Chemistry of Biological Activity
          Spring, 農学研究科
        list
          Last Updated :2022/09/30

          Administration

          School management (title, position)

          • From 01 Jan. 2022, To 31 Dec. 2023
            オープンキャンパス委員会 委員
          • From 10 Nov. 2016, To 12 Dec. 2016
            放射性同位元素総合センター液体シンチレーションカウンター仕様策定委員会 委員

          Faculty management (title, position)

          • From 01 Apr. 2019, To 31 Mar. 2023
            広報委員会 委員
          list
            Last Updated :2022/09/30

            Academic, Social Contribution

            Committee Memberships

            • From Apr. 2021, To Present
              Committee Member, Pesticide Science Society of Japan
            • From Apr. 2018, To Present
              農薬バイオサイエンス委員会(学術小集会)委員, 日本農薬学会
            • From Apr. 2021, To Mar. 2022
              JSBBA 2022 Annual Meeting Organizing Commitee, Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)
            • From Apr. 2019, To Mar. 2021
              Editorial Board Member (Managing Editor), Pesticide Science Society of Japan
            • From Apr. 2019, To Mar. 2021
              JSBBA, Kansai Branch, Committee Member, Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)

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