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Ito, Shinji
Graduate School of Medicine Program-Specific Associate Professor
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Last Updated :2025/05/02
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Last Updated :2025/05/02
Research
Papers
- Cholestasis induces reversible accumulation of periplakin in mouse liverShinji Ito; Junko Satoh; Tsutomu Matsubara; Yatrik M. Shah; Sung-hoon Ahn; Cherie R. Anderson; Weiwei Shan; Jeffrey M. Peters; Frank J. GonzalezBMC GASTROENTEROLOGY, Jul. 2013, Peer-reviewed
- Intestinal Hypoxia-inducible Transcription Factors Are Essential for Iron Absorption following Iron DeficiencyYatrik M. Shah; Tsutomu Matsubara; Shinji Ito; Sun-Hee Yim; Frank J. GonzalezCELL METABOLISM, Feb. 2009, Peer-reviewed
- Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascadeYatrik M. Shah; Shinji Ito; Keiichirou Morimura; Chi Chen; Sun-Hee Yim; Volker H. Haase; Frank J. GonzalezGASTROENTEROLOGY, Jun. 2008, Peer-reviewed
- Peroxisome proliferator-activated receptor-beta/delta protects against chemically induced liver toxicity in miceWeiwei Shan; Christopher J. Nicol; Shinji Ito; Moses T. Bility; Mary J. Kennett; Jerrold M. Ward; Frank J. Gonzalez; Jeffrey M. PetersHEPATOLOGY, Jan. 2008, Peer-reviewed
- The PPAR alpha-humanized mouse: A model to investigate species differences in liver toxicity mediated by PPAR alphaQian Yang; Tomokazu Nagano; Yatrik Shah; Connie Cheung; Shinji Ito; Frank J. GonzalezTOXICOLOGICAL SCIENCES, Jan. 2008, Peer-reviewed
- Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestineInsook Kim; Sung-Hoon Ahn; Takeshi Inagaki; Mihwa Choi; Shinji Ito; Grace L. Guo; Steven A. Kliewer; Frank J. GonzalezJOURNAL OF LIPID RESEARCH, Dec. 2007, Peer-reviewed
- Dietary phytochemicals regulate wholebody CYP1A1 expression through an arylhydrocarbon receptor nuclear translocator-dependent system in gutShinji Ito; Chi Chen; Junko Satoh; SunHee Yim; Frank J. GonzalezJOURNAL OF CLINICAL INVESTIGATION, Jul. 2007, Peer-reviewed
- Hepatocyte-restricted constitutive activation of PPAR alpha induces hepatoproliferation but not hepatocarcinogenesisQian Yang; Shinji Ito; Frank J. GonzalezCARCINOGENESIS, Jun. 2007, Peer-reviewed
- Impaired negative feedback suppression of bile acid synthesis in mice lacking beta KlothoS Ito; T Fujimori; A Furuya; J Satoh; Y Nabeshima; Y NabeshimaJOURNAL OF CLINICAL INVESTIGATION, Aug. 2005, Peer-reviewed
- Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structureS Ito; T Fujimori; Y Hayashizaki; Y NabeshimaBIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, Jul. 2002, Peer-reviewed
- Molecular cloning and expression analyses of mouse βklotho, which encodes a novel Klotho family proteinS. Ito; S. Kinoshita; N. Shiraishi; S. Nakagawa; S. Sekine; T. Fujimori; Y.-I. NabeshimaMechanisms of Development, 2000, Peer-reviewed
Misc.
- Relevant use of Klotho in FGF19 subfamily signaling system in vivoKen-ichi Tomiyama; Ryota Maeda; Itaru Urakawa; Yuji Yamazaki; Tomohiro Tanaka; Shinji Ito; Yoko Nabeshima; Tsutomu Tomita; Shinji Odori; Kiminori Hosoda; Kazuwa Nakao; Akihiro Imura; Yo-ichi NabeshimaPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2010, Peer-reviewed
External funds: Kakenhi
- Cervicovaginal fluid proteomic analysis of pregnant women after the excisional surgery for cervical lesions to elucidate the cervical mechanism for the maintenance of pregnancyGrant-in-Aid for Challenging Research (Exploratory)Medium-sized Section 56:Surgery related to the biological and sensory functions and related fieldsKumamoto University;Kyoto UniversityEiji KondohFrom 28 Jun. 2019, To 31 Mar. 2022, Project Closed妊娠;ムチン;腟分泌物;円錐切除;プロテオミクス;Mucin;早産;子宮頸部円錐切除;回収;子宮頸部;円錐切除後妊娠;プロテオーム解析
- Elucidation of the molecular mechanism of insulin resistance by investigating TBP-2/Txnip and chemical biologyGrant-in-Aid for Scientific Research (C)Kyoto UniversityHiroshi MASUTANIFrom 01 Apr. 2013, To 31 Mar. 2016, Project ClosedTxnip;糖尿病;癌;インスリン抵抗性;低分子化合物;スクリーニング;ケミカルバイオロジー;創薬;癌抑制;アルファアレスチン;イノベーション;TBP-2;化合物スクリーニング;低分子化合物スクリーニング
- Analysis of the functional roles of Periplakin in homeostasisGrant-in-Aid for Young Scientists (B)Kyoto UniversityShinji ITOFrom 01 Apr. 2012, To 31 Mar. 2014, Project ClosedＰｅｒｉｐｌａｋｉｎ;肝臓;胆汁鬱滞;糖代謝;Periplakin
- Studies on the roles of Periplakin in liverGrant-in-Aid for Young Scientists (B)Kyoto UniversityShinji ITOFrom 01 Apr. 2009, To 31 Mar. 2012, Project Closed肝臓;遺伝子発現;恒常性維持;Periplakin;胆汁鬱滞;FXR;炎症;胆汁酸;遺伝子発現制御
- βklothoノックアウトマウスを用いた新規コレステロール代謝制御機構の解析Grant-in-Aid for Young Scientists (B)Kyoto University伊藤 慎二From 01 Apr. 2004, To 31 Mar. 2007, Project ClosedβKlotho;Klotho;コレステロール;胆汁酸;Cyp7a1;Shp
- 子宮頸部のムチンタンパクMUC5B/ACによる妊娠維持機構の解明Grant-in-Aid for Scientific Research (C)Basic Section 56040:Obstetrics and gynecology-relatedKyoto University上田 優輔From 01 Apr. 2023, To 31 Mar. 2026, Suspended
- Studies on mechanisms of metastasis in colorectal cancer stem cell subtypes using mouse models and clinical materialsGrant-in-Aid for Scientific Research (C)Basic Section 49030:Experimental pathology-relatedKyoto University柿崎 文彦From 01 Apr. 2024, To 31 Mar. 2027, Grantedがん転移;がん幹細胞;マウスモデル;予後不良;トランスクリプトーム
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Last Updated :2025/05/02
Education
Teaching subject(s)
- From Apr. 2014, To Mar. 2015Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2015, To Mar. 2016Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2016, To Mar. 2017Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2017, To Mar. 2018Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2018, To Mar. 2019Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2019, To Mar. 2020Practicum on Medical ResearchYear-long, 医学研究科
- From Apr. 2020, To Mar. 2021Practicum on Medical ResearchYear-long, 医学研究科
