Basic Information

Academic Degree

• Master of Science(Nara Institute of Science and Technology)
• Doctor of Science(Nara Institute of Science and Technology)

Academic Resume (Undergraduate School/Majors)

• Kyoto University, Faculty of Integrated Human Studies, 卒業

High School

• High School

  洛星高等学校

Research History

• From Apr. 2026, To Present

  Kyoto University, Institute for the Advanced Study of Human Biology (ASHBi), Professor, Principal Investigator
• From Sep. 2020, To Mar. 2026

  Kyoto University, Institute for the Advanced Study of Human Biology (ASHBi), Associate Professor, Principal Investigator
• From 2017, To 2022

  Massachusetts Institute of Technology, McGovern Institute for Brain Research, Research Affiliate
• From 2017, To Aug. 2020

  Kyoto University, The Hakubi Center for Advanced Research/Primate Research Institute, Program-Specific Associate Professor
• From 2009, To 2017

  Massachusetts Institute of Technology, McGovern Institute for Brain Research, Research Scientist
• From 2005, To 2009

  Massachusetts Institute of Technology, McGovern Institute for Brain Research, Postdoctoral Associate/Fellow
• From 2002, To 2005

  Hokkaido University Graduate School of Medicine, Instructor
• From 2001, To 2002

  Nara Institute of Science and Technology, Postdoctoral Researcher

Profile

• Profile

  A fundamental goal of psychiatry is the ability to control emotion and anxiety. To address this, Ken-ichi developed a behavioral paradigm called, “approach-avoidance conflict,” to quantitatively characterize the value judgment in decision-making. His overarching goal is to identify the causative role of specific brain regions involved in anxiety and emotional conflict by manipulating specific brain circuits in primates and measuring the resulting changes in internal states. He plans to combine physiological, computational and anatomical methods to characterize the anxiety-related network in the cortico-basal ganglia system.

Language of Instruction

• English

ID,URL

• ORCID ID

  0000-0001-8500-6820

• J-Global ID

  201401000165967966

• Researcher number

  70344471

• External link

  https://ashbi.kyoto-u.ac.jp/lab-sites/amemori/

Website(s) (URL(s))

• https://researchmap.jp/kenamemori/?lang=english
• https://sites.google.com/view/amemorigroup/

researchmap URL

• https://researchmap.jp/kenamemori

Research

Research Topics, Overview of the research

• Research Topics

  Neurophysiology, Cognitive neuroscience, Computational neuroscience, Systems neuroscience, Decision and evaluation, Emotion, Primates, Frontal lobe, Limbic system, Basal Ganglia

• Overview of the research

  By using multi-site simultaneous neural recording and microstimulation techniques, we have studied the function of the cortico-basal ganglia circuitry concerning decision making and value evaluation. Specifically we introduced computational modeling technique to quantitatively analyze the behavior and its neural correlates. We will extend these approaches to identify the function of primates brain circuitry in relation to decision making using state-of-art techniques.

Research Interests

• Anterior cingulate cortex
• Prefrontal cortex
• Basal-ganglia
• Emotion
• Decision-making
• Computational Neuroscience
• Cognitive Neuroscience
• Systems Neuroscience
• Neurophysiology
• Neuroscience

Research Areas

• Life sciences, Basic brain sciences
• Life sciences, Clinical pharmacy
• Life sciences, Physiology
• Life sciences, Neuroscience - general, Systems, cognitive and computational neuroscience

Papers

• The mental conflict in risk-taking behavior: Decoding bias between optimism and pessimism

  Iori Higashino; Ryo Ito; Yasushi Okochi; Kengo Inutsuka; Hiroshi Yokoyama; Rikako Kato; Yuichiro Yada; Ken-ichi Amemori; Honda Naoki

  05 May 2026

  
• Functional distinctions between orbitofrontal cortex and anterior cingulate cortex subregions in decision-making and autonomic regulation

  Georgios K. Papageorgiou; Ken-ichi Amemori; Daniel J. Gibson; Helen N. Schwerdt; Michelangelo Naim; Michelle C. Wang; Tomoko Yoshida; Jitendra Sharma; Urvashi Upadhyay; Guangyu Robert Yang; Ann M. Graybiel

  Nature Communications, 14 Feb. 2026, Peer-reviewed

  
• Motivation under aversive conditions is regulated by a striatopallidal pathway in primates

  Jung-min N. OH; Satoko Amemori; Ken-ichi Inoue; Kei Kimura; Masahiko Takada; Ken-ichi Amemori

  Current Biology, Feb. 2026, Peer-reviewed, Last author, Corresponding author

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• Predictive coding in the primate brain: From visual to fronto-limbic systems

  Ryo Ito; Satoko Amemori; Ken-ichi Amemori

  Neuroscience Research, Dec. 2025, Peer-reviewed, Invited, Last author, Corresponding author

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• Differential representation of motivation and affective judgment by neurons in the primate ventral striatum and ventral pallidum during approach-avoidance decision-making

  Jung-min N. OH; Satoko Amemori; Masahiko Takada; Ken-ichi Amemori

  Neuroscience Research, Oct. 2025, Last author, Corresponding author

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• Circuit-Based Approaches to Understanding the Anterior Cingulate Cortex (ACC)

  Daulton C. Myers; Joseph Simon; Jungmin OH; Katherine E. Kabotyanski; Satoka Fujimoto; Desmond J. Oathes; Peter H. Rudebeck; Ken-ichi Amemori; Sameer A. Sheth; Julie L. Fudge

  The Journal of Neuroscience, 12 Nov. 2025, Peer-reviewed, Invited

  
• Neural mechanisms of confidence propagation in hierarchical partially observable decision-making

  Risa Katayama; Wako Yoshida; Ken-ichi Amemori; Shin Ishii

  iScience, Jul. 2025, Peer-reviewed

  
• Electrophysiological Recordings and Electrical Microstimulation in Monkey pACC and cOFC During Approach-Avoidance Behavior

  Georgios K. Papageorgiou; Daniel J. Gibson; Ken Amemori; Helen N. Schwerdt; Michelle C. Wang; Ann M. Graybiel

  Biological Psychiatry, May 2024

  
• Bridge protein-mediated viral targeting of cells expressing endogenous μ-opioid G protein-coupled receptors in the mouse and monkey brain

  Riki Kamaguchi; Satoko Amemori; Ken-ichi Amemori; Fumitaka Osakada

  Neuroscience Research, Apr. 2025, Peer-reviewed

  
• Cingulate microstimulation induces negative decision-making via reduced top-down influence on primate fronto-cingulo-striatal network

  Satoko Amemori; Ann M. Graybiel; Ken-ichi Amemori

  Nature Communications, 17 May 2024, Peer-reviewed, Last author, Corresponding author

  
• Spatiotemporal expression patterns of anxiety disorder-associated genes.

  Kalyani B Karunakaran; Ken-ichi Amemori

  Translational Psychiatry, 13 Dec. 2023, Peer-reviewed, Corresponding author

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• Generalized and social anxiety disorder interactomes show distinctive overlaps with striosome and matrix interactomes

  Kalyani B. Karunakaran; Satoko Amemori; N. Balakrishnan; Madhavi K. Ganapathiraju; Ken-ichi Amemori

  Scientific Reports, Sep. 2021, Peer-reviewed, Last author, Corresponding author

  
• The Role of the Dorsal–Lateral Prefrontal Cortex in Reward Sensitivity During Approach–Avoidance Conflict

  Camarin E Rolle; Mads L Pedersen; Noriah Johnson; Ken-ichi Amemori; Maria Ironside; Ann M Graybiel; Diego A Pizzagalli; Amit Etkin

  Cerebral Cortex, 2022, Peer-reviewed

  
• Causal Evidence for Induction of Pessimistic Decision-Making in Primates by the Network of Frontal Cortex and Striosomes

  Satoko Amemori; Ann M. Graybiel; Ken-ichi Amemori

  Frontiers in Neuroscience, 30 Jun. 2021, Peer-reviewed, Last author, Corresponding author

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• Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder

  Mads L. Pedersen; Maria Ironside; Ken-ichi Amemori; Callie L. McGrath; Min S. Kang; Ann M. Graybiel; Diego A. Pizzagalli; Michael J. Frank

  PLOS Computational Biology, 10 May 2021, Peer-reviewed

  
• Chronic multi-modal monitoring of neural activity in rodents and primates

  Helen N. Schwerdt; Dan J. Gibson; Kenichi Amemori; Lauren L. Stanwicks; Tomoko Yoshida; Michael J. Cima; Ann M. Graybiel

  Integrated Sensors for Biological and Neural Sensing, 05 Mar. 2021, Peer-reviewed

  
• Dopamine and beta-band oscillations differentially link to striatal value and motor control.

  H N Schwerdt; K Amemori; D J Gibson; L L Stanwicks; T Yoshida; N P Bichot; S Amemori; R Desimone; R Langer; M J Cima; A M Graybiel

  Science advances, Sep. 2020, Peer-reviewed

  
• Approach-Avoidance Conflict in Major Depressive Disorder: Congruent Neural Findings in Humans and Nonhuman Primates.

  Maria Ironside; Ken-Ichi Amemori; Callie L McGrath; Mads Lund Pedersen; Min Su Kang; Satoko Amemori; Michael J Frank; Ann M Graybiel; Diego A Pizzagalli

  Biological psychiatry, 2020, Peer-reviewed, Lead author

  
• Microstimulation of primate neocortex targeting striosomes induces negative decision-making.

  Satoko Amemori; Ken-Ichi Amemori; Tomoko Yoshida; Georgios K Papageorgiou; Rui Xu; Hideki Shimazu; Robert Desimone; Ann M Graybiel

  The European journal of neuroscience, 2020, Peer-reviewed

  
• Striatal Beta Oscillation and Neuronal Activity in the Primate Caudate Nucleus Differentially Represent Valence and Arousal Under Approach-Avoidance Conflict.

  Ken-Ichi Amemori; Satoko Amemori; Daniel J Gibson; Ann M Graybiel

  Frontiers in neuroscience, 2020, Peer-reviewed, Lead author, Corresponding author

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• Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes.

  Simon Hong; Satoko Amemori; Emily Chung; Daniel J Gibson; Ken-Ichi Amemori; Ann M Graybiel

  Current biology : CB, 07 Jan. 2019, Peer-reviewed

  
• Striatal Microstimulation Induces Persistent and Repetitive Negative Decision-Making Predicted by Striatal Beta-Band Oscillation.

  Ken-Ichi Amemori; Satoko Amemori; Daniel J Gibson; Ann M Graybiel

  Neuron, 22 Aug. 2018, Peer-reviewed

  
• Miniaturized neural system for chronic, local intracerebral drug delivery.

  Canan Dagdeviren; Khalil B Ramadi; Pauline Joe; Kevin Spencer; Helen N Schwerdt; Hideki Shimazu; Sebastien Delcasso; Ken-Ichi Amemori; Carlos Nunez-Lopez; Ann M Graybiel; Michael J Cima; Robert Langer

  Science translational medicine, 24 Jan. 2018, Peer-reviewed

  
• Long-term dopamine neurochemical monitoring in primates.

  Helen N Schwerdt; Hideki Shimazu; Ken-Ichi Amemori; Satoko Amemori; Patrick L Tierney; Daniel J Gibson; Simon Hong; Tomoko Yoshida; Robert Langer; Michael J Cima; Ann M Graybiel

  Proceedings of the National Academy of Sciences of the United States of America, 12 Dec. 2017, Peer-reviewed

  
• Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making.

  Alexander Friedman; Daigo Homma; Bernard Bloem; Leif G Gibb; Ken-Ichi Amemori; Dan Hu; Sebastien Delcasso; Timothy F Truong; Joyce Yang; Adam S Hood; Katrina A Mikofalvy; Dirk W Beck; Norah Nguyen; Erik D Nelson; Sebastian E Toro Arana; Ruth H Vorder Bruegge; Ki A Goosens; Ann M Graybiel

  Cell, 16 Nov. 2017, Peer-reviewed

  
• Habit Learning by Naive Macaques Is Marked by Response Sharpening of Striatal Neurons Representing the Cost and Outcome of Acquired Action Sequences.

  Theresa M Desrochers; Ken-ichi Amemori; Ann M Graybiel

  Neuron, 19 Aug. 2015, Peer-reviewed

  
• A Corticostriatal Path Targeting Striosomes Controls Decision-Making under Conflict.

  Alexander Friedman; Daigo Homma; Leif G Gibb; Ken-Ichi Amemori; Samuel J Rubin; Adam S Hood; Michael H Riad; Ann M Graybiel

  Cell, 04 Jun. 2015, Peer-reviewed

  
• Motivation and affective judgments differentially recruit neurons in the primate dorsolateral prefrontal and anterior cingulate cortex.

  Ken-ichi Amemori; Satoko Amemori; Ann M Graybiel

  The Journal of neuroscience : the official journal of the Society for Neuroscience, 04 Feb. 2015, Peer-reviewed, Lead author

  
• A non-invasive head-holding device for chronic neural recordings in awake behaving monkeys.

  Satoko Amemori; Ken-Ichi Amemori; Margaret L Cantor; Ann M Graybiel

  Journal of neuroscience methods, 30 Jan. 2015, Peer-reviewed

  
• Localized microstimulation of primate pregenual cingulate cortex induces negative decision-making.

  Ken-ichi Amemori; Ann M Graybiel

  Nature neuroscience, May 2012, Peer-reviewed, Lead author

  
• A system for recording neural activity chronically and simultaneously from multiple cortical and subcortical regions in nonhuman primates.

  Joseph Feingold; Theresa M Desrochers; Naotaka Fujii; Ray Harlan; Patrick L Tierney; Hideki Shimazu; Ken-Ichi Amemori; Ann M Graybiel

  Journal of neurophysiology, Apr. 2012, Peer-reviewed

  
• Wearable wireless sensor platform for studying autonomic activity and social behavior in non-human primates.

  Richard Ribón Fletcher; Ken-ichi Amemori; Matthew Goodwin; Ann M Graybiel

  Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2012, Peer-reviewed

  
• Shifting responsibly: the importance of striatal modularity to reinforcement learning in uncertain environments.

  Ken-Ichi Amemori; Leif G Gibb; Ann M Graybiel

  Frontiers in human neuroscience, 2011, Peer-reviewed, Invited, Lead author

  
• Contrasting effects of reward expectation on sensory and motor memories in primate prefrontal neurons.

  Ken-ichi Amemori; Toshiyuki Sawaguchi

  Cerebral cortex (New York, N.Y. : 1991), Jul. 2006, Peer-reviewed, Lead author

  
• Rule-dependent shifting of sensorimotor representation in the primate prefrontal cortex.

  Ken-ichi Amemori; Toshiyuki Sawaguchi

  The European journal of neuroscience, Apr. 2006, Peer-reviewed, Lead author

  
• Self-organization of delay lines by spike-time-dependent learning

  Amemori, K.-I.; Ishii, S.

  Neurocomputing, 2004, Peer-reviewed, Lead author

  
• Resonance of a stochastic spiking neuron mimicking the Hodgkin-Huxley model

  Amemori, K.-I.; Ishii, S.

  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2001, Peer-reviewed, Lead author

  
• Gaussian process approach to stochastic spiking neurons with reset

  Amemori, K.-I.; Ishii, S.

  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2001, Peer-reviewed, Lead author

  
• Gaussian process approach to spiking neurons for inhomogeneous Poisson inputs

  Amemori, K.-I.; Ishii, S.

  Neural Computation, 2001, Peer-reviewed, Lead author

  
• Ensemble average and variance of a stochastic spiking neuron model

  Amemori, K.; Ishii, S.

  IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2000, Peer-reviewed, Lead author

  
• Self-Organization and Association for Fine Spatio-Temporal Spike Sequences

  Amemori K; Ishii S

  Transactions of the Institute of Systems, Control and Information Engineers, 2000, Peer-reviewed, Lead author

  
• Unsupervised learning for sub-millisecond temporal coded sequence

  Amemori K; Ishii S

  JCIS 98 Proceedings, 1998, Peer-reviewed, Lead author

  
• Self-organizing network learning of sub-millisecond temporal coded information

  K Amemori; S Ishii

  ICONIP'98: THE FIFTH INTERNATIONAL CONFERENCE ON NEURAL INFORMATION PROCESSING JOINTLY WITH JNNS'98: THE 1998 ANNUAL CONFERENCE OF THE JAPANESE NEURAL NETWORK SOCIETY - PROCEEDINGS, VOLS 1-3, 1998, Peer-reviewed, Lead author

  
• Multiplexed action-outcome representation by striatal striosome-matrix compartments detected with a mouse cost-benefit foraging task.

  Bernard Bloem; Rafiq Huda; Ken-ichi Amemori; Alex S. Abate; Gayathri Krishna; Anna L. Wilson; Cody W. Carter; Mriganka Sur; Ann M. Graybiel

  Nature Communications, 2022, Peer-reviewed

  

Misc.

• Neural oscillatory signals representing uncertainty in decision-making in the primate anterior insular cortex.

  ryo ito; rikako kato; shin ishii; ken-ichi amemori

  Society for Neuroscience, Abstract, Nov. 2025, Last author, Corresponding author

  
• Physiological and Genetic Mapping of Anxiety and Depression Networks in Primates

  Ken-ichi Amemori

  NEURO2025 (The 48th Annual Meeting of the Japan Neuroscience Society), Jul. 2025, Invited, Lead author

  
• Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation

  Georgios K. Papageorgiou; Daniel J. Gibson; Ken-ichi Amemori; Helen N. Schwerd; Michelangelo Naim; Michelle C. Wang; Tomoko Yoshida; Jitendra Sharma; Urvashi Upadhyay; Guangyu Robert Yang; Ann M. Graybie

  2025, Peer-reviewed

  
• Interactome modules underlie shared spatiotemporal signatures in psychiatric and neurodegenerative disorders

  Kalyani B. Karunakaran; Jayant Mahadevan; Suhas Ganesh; Meera Purushottam; N; Balakrishnan; Ken-ichi Amemori; Biju Viswanath; Sanjeev Jain

  World Congress of Psychiatric Genetics, 2025, Peer-reviewed

  
• Causal role of the primate anterior insular cortex in decision making with uncertainty of reward acquisition.

  Ryo Ito; Rikako Kato; Shin Ishii; Ken-ichi Amemori

  NEURO2024 (The 47th Annual Meeting of the Japan Neuroscience Society, The 67th Annual Meeting of the Japanese Society for Neurochemistry, The 46th Annual Meeting of the Japanese society of Biological Psychiatry, The 8th FAONS Congress), 2024

  
• Macaque model of major depressive disorder: Cingulate microstimulation induces reduced top-down influence on limbic network

  Satoko Amemori; Ann M Graybiel; Ken-Ichi Amemori

  NEURO2024 (The 47th Annual Meeting of the Japan Neuroscience Society, The 67th Annual Meeting of the Japanese Society for Neurochemistry, The 46th Annual Meeting of the Japanese society of Biological Psychiatry, The 8th FAONS Congress), 2024

  
• Cingulate microstimulation induces negative bias via dampened top-down cognitive influence on primate limbic network

  Satoko Amemori; Ann M Graybiel; K-I Amemori

  FENS Forum 2024 Abstract: 2288, 2024

  
• Selective silencing of the ventral striatum-ventral pallidum pathway enhances approach choices and motivational states under approach-avoidance conflict in nonhuman primates

  J. N. OH; S. AMEMORI; K.-I. INOUE; K. KIMURA; M. TAKADA; K.-I. AMEMORI

  Society for Neuroscience, abstract,, 2023

  
• Reduced top-down influence in the primate fronto-cingulo-striatal network underlying negative bias in conflict decision-making.

  S. AMEMORI; A. M. GRAYBIEL; K. AMEMORI

  Society for Neuroscience, abstract,, 2023

  
• Orbitofrontal and anterior cingulate circuits in primates: complementary roles in cost-benefit decision-making and learning.

  G. K; PAPAGEORGIOU; D. GIBSON; K.-I. AMEMORI; H. SCHWERDT; M. C. WANG; J. SHARMA; A. M. GRAYBIEL

  Society for Neuroscience, Abstract, 2023

  
• Electrophysiological Recordings and Electrical Microstimulation in Monkey pACC and cOFC During Approach-Avoidance Behavior

  Georgios K. Papageorgiou; Daniel J. Gibson; Ken Amemori; Helen N. Schwerdt; Michelle C. Wang; Ann M. Graybiel

  Biological Psychiatry, May 2024

  
• 不安と葛藤の制御のための生理学的・遺伝学的アプローチ

  雨森賢一

  2023

  
• Pathway-selective silencing of ventral striatum neurons projecting to the ventral pallidum elevates motivational states under approach-avoidance conflict in nonhuman primates

  J. Oh; S. Amemori; K. Inoue; K. Kimura; M. Takada; K. Amemori

  Society for Neuroscience abstract, Nov. 2021, Corresponding author

  
• 【意思決定と行動選択の神経科学】障害・病態 不安

  雨森 賢一

  Clinical Neuroscience, Aug. 2021

  
• 接近回避葛藤下の意思決定を制御する前帯状皮質-ストリオソーム回路

  雨森 賢一

  ブレインサイエンス・レビュー, Mar. 2020

  
• 【前頭葉-脳の司令塔】基礎 前帯状皮質 線条体における不安のメカニズム

  雨森 賢一

  Clinical Neuroscience, Feb. 2020

  
• Mechanism of anxiety induction in the anterior cingulate cortex-striatum pathway

  Ken-ichi Amemori

  Clinical Neuroscience, Feb. 2020, Lead author, Corresponding author

  
• 不安や悲観的判断に関わる霊長類側坐核経路の機能解明

  雨森 賢一

  上原記念生命科学財団研究報告集, Dec. 2019

  
• 不安や悲観的判断に関わる霊長類側坐核経路の機能解明

  雨森 賢一

  上原記念生命科学財団研究報告集, Dec. 2019, Corresponding author

  
• 情動の神経機構とその異常としての精神疾患病態の解明 接近回避葛藤下の意思決定を制御する前帯状皮質膝前部-ストリオソーム回路

  雨森 賢一

  日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集, Oct. 2019

  
• Neurons in the primate nucleus accumbens dissociate motivation and value under the approach-avoidance decision-making.

  Oh Jungmin; Masahiko Takada; Amemori, K

  The 42nd Annual Meeting of the Japan Neuroscience Society, 2019, Corresponding author

  
• Distinct roles of the pACC and cOFC in cost-benefit decision-making

  Papageorgiou GK; Amemori K; Schwerdt HN; Gibson DJ; Graybiel AM

  Society for Neuroscience Abstract, 2019

  
• Synchronous recording of dopamine neurochemical and striatal electrical activity in non-human primates

  Schwerdt HN; Amemori K; Gibson DJ; Stanwicks L; Yoshida T; Amemori S; Langer R; Cima MJ; Graybiel AM

  Society for Neuroscience Abstract, 2019

  
• Striatal beta oscillation and neuronal activity in the primate caudate nucleus differentially represent valence and arousal under approach-avoidance conflict

  Amemori K; Amemori S; Gibson DJ; Graybiel AM

  Society for Neuroscience Abstract, 2019, Lead author

  
• Microstimulation of primate caudate nucleus induces an abnormal repetition of negative decisions predicted by beta oscillatory activity

  K Amemori; S Amemori; DJ Gibson; AM Graybiel

  The 41st Annual Meeting of the Japan Neuroscience Society, Jul. 2018

  
• Computational phenotyping of brain-behavioral relationships underlying approach-avoidance decision making in major depressive disorder

  Pedersen ML; Ironside M; McGrath CL; Amemori K; Kang M; Graybiel AM; Frank MJ; Pizzagalli DA

  Society for Neuroscience Abstract, 2018

  
• Electrochemical recording of striatal dopamine in non-human primates performing reward-biased tasks

  Schwerdt HN; Stanwicks L; Amemori K; Shimazu H; Yoshida T; Amemori S; Langer R; Cima MJ; Graybiel AM

  Society for Neuroscience Abstract, 2018

  
• Beta oscillations in the primate striatum predict repetitive negative decision-making states induced by microstimulation

  Amemori K; Amemori S; Gibson DJ; Graybiel AM

  Society for Neuroscience Abstract, 2018, Peer-reviewed, Invited

  
• The Neurocircuitry of Approach-Avoidance Decisions in Depression: Towards a Cross Species Model of Utility and Motivation

  Maria Ironside; Ken-ichi Amemori; Min Su Kang; Jeffrey Curry; Callie McGrath; Ann Graybiel; Amit Etkin; Diego Pizzagalli

  NEUROPSYCHOPHARMACOLOGY, Nov. 2017

  
• The Neurocircuitry of Approach-Avoidance Decisions in Depression: I. Neuroeconomic Modeling of Reward and Utility in Decision-Making

  Min Su Kang; Maria Ironside; Ken-ichi Amemori; Jeffrey Curry; Malavika Mehta; Callie McGrath; Ann Graybiel; Diego Pizzagalli

  NEUROPSYCHOPHARMACOLOGY, Nov. 2017

  
• 情動・報酬と前頭葉機能 霊長類の線条体のコントロールによる悲観的な意思決定の持続

  雨森 賢一

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集, Sep. 2017

  
• Microstimulation-recording experiments demonstrate that striosomes in non-human primate control spike activity in the lateral habenula

  Hong S; Amemori S; Chung E; Amemori K; Graybiel AM

  Society for Neuroscience Abstract, 2017

  
• Rescue and mimicking of chronic stress effects on cost-benefit decision-making by manipulation of a cortico-striosomal circuit

  Homma D; Friedman A; Bloem B; Gibb LG; Amemori K; Hu D; Delcasso S; Hood AS; Yang J; Mikofalvy KA; Truong TF; Toro Arena SE; Beck DW; Nguyen N; Vorder Bruegge RH; Nelson ED; Goosens KA; Graybiel AM

  Society for Neuroscience Abstract, 2017

  
• Hodgkin-Huxley models of excitatory-inhibitory balance in a cortico-striosomal circuit underlying aberrant cost-benefit decision-making caused by chronic stress

  Gibb LG; Friedman A; Homma D; Bloem B; Amemori K; Hu D; Delcasso S; Hood AS; Yang J; Mikofalvy KA; Truong TF; Toro Arena SE; Beck DW; Nguyen N; Vorder Bruegge RH; Nelson ED; Goosens KA; Graybiel AM

  Society for Neuroscience Abstract, 2017

  
• A shift in the excitation-inhibition balance of a cortico-striosomal circuit underlies aberrant cost-benefit decision-making caused by chronic stress

  Friedman A; Homma D; Bloem B; Gibb LG; Amemori K; Hu D; Delcasso S; Hood AS; Yang J; Mikofalvy KA; Truong TF; Toro Arena SE; Beck DW; Nguyen N; Vorder Bruegge RH; Nelson ED; Goosens KA; Graybiel AM

  Society for Neuroscience Abstract, 2017

  
• Electrochemical recording of pharmacologically modulated dopamine from sensors chronically implanted in striatum of awake non-human primates

  Schwerdt HN; Shimazu H; Amemori K; Amemori S; Hong S; Yoshida T; Langer R; Cima MJ; Graybiel AM

  Society for Neuroscience Abstract, 2017

  
• Striatal beta-band oscillations associated with long-lasting pessimistic mood induced by intrastriatal microstimulation

  K. Amemori; S. Amemori; D.J. Gibson; A.M. Graybiel

  Society for Neuroscience Abstract, 2016

  
• Striosomes may control dopamine activity via disynaptic projections to macaque lateral habenula

  S. Hong; S. Amemori; K. Amemori; A.M. Graybiel

  Society for Neuroscience Abstract, 2016

  
• 慢性埋込みカーボンファイバー電極とin vivoボルタメトリーを用いた覚醒サル線条体からのドパミン計測の試み

  島津 秀紀; シュバート・ヘレン; 雨森 賢一; ホン・サイモン; グレイヴィール・アン

  臨床神経生理学, Oct. 2015

  
• Properties of striatal beta oscillation at sites identified by microstimulation as controlling approach-avoidance choice behavior

  K. Amemori; S. Amemori; D.J. Gibson; A.M. Graybiel

  Society for Neuroscience Abstract, 2015

  
• Compartmental selectivity of a prefronto-striosomal pathway controlling decision-making under motivational conflict

  D. Homma; A. Friedman; L.G. Gibb; K. Amemori; S.J. Rubin; A.S. Hood; M.H. Ria; A.M. Graybiel

  Society for Neuroscience Abstract, 2015

  
• Striatal high-firing interneurons mediate inhibitory prefrontal-striosomal signaling during cost-benefit conflict decision-making

  A. Friedman; D. Homma; L.G. Gibb; K. Amemori; S.J. Rubin; A.S. Hood; M.H. Ria; A.M. Graybiel

  Society for Neuroscience Abstract, 2015

  
• A medial prefrontal-striosome circuit is selectively engaged by cost-benefit conflict decision-making

  L.G. Gibb; A. Friedman; D. Homma; K. Amemori; S.J. Rubin; A.S. Hood; M.H. Ria; A.M. Graybiel

  Society for Neuroscience Abstract, 2015

  
• Fast-scan cyclic voltammetric measurements of stimulation-induced dopamine release with chronically implanted carbon fibers in awake non-human primate

  H.N. Schwerdt; H. Shimazu; K. Amemori; S. Hong; J.C. Sy; K.C. Spencer; P.L. Tierney; Y. Yang; H. Yerramreddy; C. Dagdeviren; K. Ramadi; R.S. Langer; M.J. Cima; A.M. Graybiel

  Society for Neuroscience Abstract, 2015

  
• Neural responses in striatum related to cost and outcome can drive unsupervised learning in the macaque

  Theresa Desrochers; Ken-ichi Amemori; Ann Graybiel

  Society for Neuroscience Abstract, 2014

  
• Striatal neuronal activity of macaque tracks local and global changes during natural habit formation

  Theresa Desrochers; Ken-ichi Amemori; Ann Graybiel

  Cosyne 2014, 2014, Peer-reviewed

  
• Primate dorsolateral prefrontal and anterior cingulate neurons are differentially recruited during decision-making under approach-avoidance conflict

  K. Amemori; S. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2013

  
• Low-dose NMDA antagonist treatment induces frequency-specific changes in lfp across primate cortico-striatal circuits during approach-avoidance decision-making

  S. Amemori; K. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2013

  
• Microstimulation of macaque subgenual anterior cingulate cortex alters approach-avoidance decision-making.

  S. Amemori; K. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2012

  
• Functional clustering of neurons in primate caudate nucleus related to outcome evaluation for approach-avoidance decision-making.

  K. Amemori; S. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2012

  
• The striatum as a context-sensitive modular reinforcement learning system adaptable to changing environments.

  L. G. Gibb; K. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2011

  
• Effects of anxiolytic drug administration on macaque decision-making under approach-avoidance conflict

  S. Amemori; K. Amemori; A. M. Graybiel

  Society for Neuroscience Abstract, 2011

  
• Localized microstimulation of macaque pregenual anterior cingulate cortex increases rejection of cued outcomes in approach-avoidance decision-making.

  Ken-ichi Amemori; Ann M. Graybiel

  Society for Neuroscience Abstract, 2010

  
• Stimulation of the macaque rostral anterior cingulate cortex alters decision in approach-avoidance conflict.

  Ken-ichi Amemori; Ann M. Graybiel

  Society for Neuroscience Abstract, 2009

  
• Monkey eye movement patterns in a free-viewing scan task: Reward and reduction of entropy as drives.

  T. M. Desrochers; K. Amemori; D. Z. Jin; A. M. Graybiel

  Society for Neuroscience Abstract, 2009

  
• Enhancement of neuronal activity in the primate anterior cingulate cortex during approach-avoidance conflict

  Ken-ichi Amemori; Ann M. Graybiel

  Society for Neuroscience Abstract, 2008

  
• 記憶誘導性の感覚運動変換におけるサル前頭前皮質と前頭眼野ニューロンの機能的差異(Functional differences between primate prefrontal and frontal eye field neurons in a memory-guided sensorimotor transformation)

  雨森 賢一; 澤口 俊之

  神経化学, Aug. 2004

  
• Different motivational effects on the neuronal activities for sensory mamory and saccade preparation in the primate frontal eye field.

  Ken-ichi Amemori; Toshiyuki Sawaguchi

  Society for Neuroscience Abstract, 2004

  
• 感覚記憶から運動へと再現情報を変化させるサル前頭前皮質ニューロン

  雨森 賢一; 澤口 俊之

  日本生理学雑誌, Dec. 2003

  
• Different motivational effect on the neuronal activities in the primate prefrontal cortex during a sensorimotor transformation task

  Ken-ichi Amemori; Toshiyuki Sawaguchi

  Society for Neuroscience Abstract, 2003

  
• Neuronal representations in the primate dorsolateral prefrontal cortex during memory-guided sensorimotor transformation process.

  Ken-ichi Amemori; Toshiyuki Sawaguchi

  Neuroscience Research, 2003

  
• 視覚・運動変換におけるサル前頭前皮質のニューロン活動の報酬依存性

  雨森 賢一; 澤口 俊之

  日本生理学雑誌, Oct. 2002

  
• Change in the single spike response of the Hodgkin-Huxley neuron based on excitatory and inhibitory background inputs

  Kuboshima Satoko; Amemori Ken-ichi; Sakumura Yuichi; Ishii Shin

  IEICE technical report. Neurocomputing, Jan. 2002

  
• NLP2000-30 / NC2000-24 Variation of the Response functions in stochastic spiking neuron model

  Amemori Ken-ichi; Ishii Shin

  IEICE technical report. Neurocomputing, Jun. 2000

  
• NLP2000-30 / NC2000-24 Variation of the Response functions in stochastic spiking neuron model

  Amemori Ken-ichi; Ishii Shin

  IEICE technical report. Nonlinear problems, Jun. 2000

  
• Response of spiking nenrons to Poisson spikes

  Amemori kenichi; Kubo Masayoshi; Ishii Shin

  IEICE technical report. Neurocomputing, Mar. 2000

  
• Spike-based Hebbian Delay Adaptation

  Keyakidani Dai; Amemori Kenichi; Ishii Shin

  IEICE technical report. Nonlinear problems, Mar. 2000

  
• Effect of the synaptic time constant on stochastic spiking neurons

  Amemori, K; Ishii, S

  Proceedings of the 7th International Conference on Neural Information Processing, 2000, Peer-reviewed

  
• Association of fine spatio-temporal sequence by a Hebbian spike-based learning rule

  Amemori Kenichi; Ishii Shin

  IEICE technical report. Neurocomputing, Mar. 1999

  
• Self-organization and association for temporal coding

  K Amemori; S Ishii

  NINTH INTERNATIONAL CONFERENCE ON ARTIFICIAL NEURAL NETWORKS (ICANN99), VOLS 1 AND 2, 1999, Peer-reviewed

  
• Unsupervised learning of temporal sequence coded by small interval differences

  Amemori Kenichi; Ishii Shin

  IEICE technical report. Neurocomputing, Jul. 1998

  

Presentations

• Neural Mechanisms of Anxiety and Motivation in Primates – Genes, Neural Circuits and Behavior –

  Ken-ichi Amemori

  Fujita medical university ICBS seminar, 15 May 2025, Invited

  
• 脳の中にある『不安の源』をさがして

  Ken-ichi Amemori

  市民公開講座「脳科学の達人2025」, 27 Jul. 2025, Invited

  
• Integrative Physiological and Genetic Mapping of Anxiety-Related Networks in Non-Human Primates

  Ken-ichi Amemori

  QST symposium, Jul. 2025, Invited

  
• ストレスに対する情動反応の神経回路の解明と制御：非ヒト霊長類におけるうつ様状態の制御

  雨森賢一

  AMED PRIME 第２期 ③「ストレス」 キックオフ・領域会議, 11 Feb. 2025, Invited

  
• Predictive coding for anxiety control: hierarchical network in the primate cognitive-limbic system

  Ken-ichi Amemori

  4th meeting: unified theory of prediction and action, 11 Nov. 2024, Invited

  
• モティベーションと意思決定を統合する大脳基底核回路

  雨森賢一

  大阪大学蛋白質研究所セミナー「意思決定の分子・回路・計算機構」, 11 Nov. 2024, Invited

  
• 不確かさの不安に因果的に関わる霊長類皮質―皮質下ネットワークのダイナミクス解明

  雨森賢一

  脳神経科学統合プログラム 中核拠点・個別課題合同キックオフ会議, 13 Oct. 2024, Invited

  
• Why Is It Hard to Feel Motivated for Unpleasant Tasks? Regulating Anxiety and Depression through Physiological and Genetic Approaches in Primates

  Ken-ichi Amemori

  Reward, Motivation, and Beyond: Neural Basis of Communication, Part 2 Workshop on the Systems Neuroscience Approach, 13 Oct. 2024, Invited

  
• Predictive coding for anxiety control: hierarchical network in the primate cognitive-limbic system

  Ken-ichi Amemori

  3rd meeting: unified theory of prediction and action, May 2024, Invited

  
• 霊長類の不安と葛藤の制御のための 生理学的・遺伝学的アプローチ

  雨森 賢一

  2024年３月度「マーモセットミーティング」, Mar. 2024, Invited

  
• 霊長類の不安と葛藤の制御のための 生理学的・遺伝学的アプローチ

  雨森賢一

  京都大学ヒト行動進化研究センター 国際脳科学シンポジウム, 2024, Invited

  
• 不安と葛藤の制御のための生理学的・遺伝学的アプローチ

  雨森賢一

  生理研 セミナー, 2023, Invited

  
• 不安と葛藤を制御する 霊長類辺縁皮質－ストリオソーム回路

  Ken-ichi Amemori

  次世代脳 脳情報動態・時間生成学・超適応 －若手研究者合同シンポジウム－, 16 Dec. 2021, Invited

  
• Neuroscientific and computational bases of the hierarchical network of anxiety in primates

  Ken-ichi Amemori

  The free energy principle of the brain: experiments and verification, 14 Dec. 2021, Invited

  
• Causal Evidence for Induction of Anxiety-like State in Primates by the Network of Frontal Cortex and Striosomes

  Ken-ichi Amemori

  Farewell ceremony of 7th-batch Hakubi researchers, 17 Sep. 2021, Invited

  
• サル前頭前皮質腹内側部の 接近回避葛藤に対する神経応答と神経操作

  Ken-ichi Amemori

  2021年度 超適応A班WEB会議, 16 Sep. 2021, Invited

  
• Computational and physiological basis of cortico-basal ganglia circuits generating anxiety-like states in primates

  Ken-ichi Amemori

  JANUBET Primate Neurobiology School, 14 Sep. 2021, Invited

  
• 不安や意欲を司る霊長類神経ネットワーク の解析と操作

  Ken-ichi Amemori

  ReCoCo@KRP, 05 Aug. 2021, Invited

  
• Computational and Physiological Approaches to the Primate Anxiety Connectome

  Ken-ichi Amemori

  SPP-2041 Meeting, 12 Apr. 2021, Invited

  
• Striatal module hypothesis for flexible switching of approach-avoidance conflict

  Ken-ichi Amemori

  NIPS workshop 2020, 14 Sep. 2020, Invited

  
• 「不安の源」は脳の中にある

  雨森 賢一

  43回日本神経科学大会 市民公開パネルディスカッション「2050年の脳科学と社会」, 01 Aug. 2020, Invited

  
• Identifying the function of primate striosome-related circuitry on pessimistic valuation and anxiety

  Ken-ichi Amemori

  The 43rd Annual Meeting of the Japan Neuroscience Society, Jul. 2020, Invited

  
• Physiological approach to identify primate cortico-basal ganglia circuits that generate anxiety

  Ken-ichi Amemori

  The 43rd Annual Meeting of the Japan Neuroscience Society, Jul. 2020

  
• Role of striosome – matrix compartments in modular reinforcement learning: how striatal dysfunction induces persistent and repetitive decision-making

  Ken-ichi Amemori

  MACS International Symposium: Computational principles in active perception and reinforcement learning, 14 Feb. 2020, MACS program, Kyoto University, Invited

  
• Physiological and Genetic Approaches to Identify Primate Cortico-Basal Ganglia Structures Generating Anxiety

  Ken-ichi Amemori

  ASHBi SEMINAR, 24 Jan. 2020, Invited

  
• Striatal beta oscillation in the primate caudate nucleus sequentially responded to valence and arousal under approach-avoidance conflict

  Ken-ichi Amemori

  Oscillology The 2nd workshop in 2019, 21 Dec. 2019, Invited

  
• Physiological and Genetic Approaches to Identify Primate Striatal Structures Causally Involved in Generating Anxiety

  Ken-ichi Amemori

  Brainfodynamics The 4th workshop, 17 Dec. 2019, Invited

  
• Congruent cingulate responses of humans and macaques to anxiety and conflict

  Ken-ichi Amemori

  176th Hakubi Seminar, 10 Dec. 2019, Invited

  
• Microstimulation of primate neocortex targeting striosomes induces negative decision-making

  Ken-ichi Amemori

  AsCNP/JSNP/JSCNP 2019, 12 Oct. 2019, Invited

  
• Striatal beta oscillation and neuronal activity in the primate caudate nucleus differentially represent valence and arousal under approach-avoidance conflict

  Ken-ichi Amemori

  NEURO2019 (The 42nd Annual Meeting of the Japan Neuroscience Society and the 62nd Annual Meeting of the Japanese Society for Neurochemistry), 27 Jul. 2019

  
• Primate cortico-striosome circuit was causally related to the induction of pessimistic decision-making

  Ken-ichi Amemori

  Neuroscience 2019 Satellite Symposium Basal Ganglia in Health and Disease, 24 Jul. 2019, Invited

  
• Stimulation of Primate Cortex Targeting Striosomes Induces Negative Decision-making under Approach-Avoidance Conflict

  Ken-ichi Amemori

  Brainfodynamics The 3rd workshop, 02 Jul. 2019, Invited

  
• Striatal beta oscillation and neuronal activity in the primate caudate nucleus differentially represent valence and arousal under approach-avoidance conflict

  Ken-ichi Amemori

  Oscillology The first workshop in 2019, 18 Jun. 2019, Invited

  
• Seeking to understand primate's anxiety circuit

  Ken-ichi Amemori

  The 33rd Annual Conference of the Japanese Society for Artificial Intelligence, 2019, 04 Jun. 2019, Invited

  
• A cortico-basal ganglia circuit generating anxiety state and decisions under conflict in primates.

  Ken-ichi Amemori

  Frontier Biosciences Seminars (Osaka University), 17 May 2019, Invited

  
• Cortico-basal ganglia circuits generating anxiety-like states in primates.

  Ken-ichi Amemori

  German–Japanese Workshop, New Directions In Systems Neuroscience (University of Tübingen), 21 Mar. 2019, Invited

  
• A cortico-basal ganglia circuit generating anxiety-like state in primates.

  Ken-ichi Amemori

  Hakubi Annual Report (Kyoto University) 2019., 15 Mar. 2019, Invited

  
• Cortico-striosome pathway in decision-making and anxiety

  Ken-ichi Amemori

  The Hakubi Autumn Camp (Hakubi Center, Kyoto University), 14 Dec. 2018, Invited

  
• Dissociable roles of cortico-striatal circuits in inducing abnormally repetitive negative decisions in primates

  Ken-ichi Amemori

  Interdisciplinary Seminar on Primatology (Primate Research Institute, Kyoto University), 07 Dec. 2018, Invited

  
• Searching for a causal role of the primate striatum in repetitive negative decision-making

  Ken-ichi Amemori

  Ishii lab seminar (京都大学情報学研究科), 26 Jun. 2018, Invited

  
• 悲観的な価値判断と相関する大脳皮質ｰ線条体における新たなベータ波

  雨森 賢一

  「オシロロジー」 2018 年度第 1 回領域会議, 10 Jun. 2018, Invited

  
• Identification of primate emotional circuits controlling anxiety and persistency

  Ken-ichi Amemori

  Conference for Joint Usage (Kyoto University Primate Research Institute), 23 Feb. 2018, Invited

  
• Anxiety circuit around cingulate cortex and social neuroscience

  Ken-ichi Amemori

  NIPS Research Meeting (National Institute for Physiological Sciences), 30 Nov. 2017, Invited

  
• Control of primate’s decision-making and functional identification of the cortico-striatal circuitry

  Ken-ichi Amemori

  The 7th NIPS / CIN Joint Symposium, 28 Nov. 2017, Invited

  
• 霊長類の線条体のコントロールによる悲観的な意思決定の持続

  雨森 賢一

  第39回日本生物学的精神医学会 第47回日本神経精神薬理学会 合同大会（札幌コンベンションセンター）, 29 Sep. 2017, Invited

  
• 霊長類の辺縁系コントロールと悲観的な意思決定の固執

  雨森 賢一

  第１２７回ニューロサイエンス談話会（北海道大学）, 28 Sep. 2017, Invited

  
• Mapping emotional circuitry by controlling primate's evaluation

  Ken-ichi Amemori

  NIPS Research Meeting (National Institute for Physiological Sciences), Sep. 2017, Invited

  
• Control and functional identification of primate’s anxiety-related cortico-striatal circuitry

  Ken-ichi Amemori

  Neuroscience seminar series (Kyoto University, Graduate School of Medicine), Jul. 2017, Invited

  
• A computational approach to identify the representation and function of cortico-striatal circuit for affective decision-making

  Ken-ichi Amemori

  Ishii lab seminar (Kyoto University), 23 Jun. 2017, Invited

  
• Control of primate’s decision-making and functional identification of the brain circuitry

  Ken-ichi Amemori

  Hakubi seminar (Kyoto University), 09 May 2017, Invited

  
• Control of primate brain to regulate anxiety and conflict

  Ken-ichi Amemori

  Primate Research Institute (Kyoto University), Jan. 2017, Invited

  
• Control of primate Cortico-basal ganglia circuit to modulate anxiety and conflict

  Ken-ichi Amemori

  Neuroscience Talk Series (Hokkaido University), May 2016, Invited

  
• Mathematical approaches for neuroscience of emotion

  Ken-ichi Amemori

  Kansai Medical University, May 2016, Invited

  
• Non-human primate models of depression and stress-related disorder

  Ken-ichi Amemori

  Beyond Monoamines: Toward New Conceptualizations and Treatments for Major Depression (Radcliffe Institute, Harvard), Aug. 2015, Invited

  
• Controlling Anxiety in Primate: A Cortico-Striatal Circuit that Governs Approach-Avoidance Decisions

  Ken-ichi Amemori

  McLean Center for Depression, Anxiety and Stress Research Speaker Series (McLean Hospital, Harvard Medical School), 2014, Invited

  
• Control of primate’s benefit-cost ratio by manipulating localized circuits in the frontostriatal network.

  A. M. Graybiel; K. Amemori

  Society for Neuroscience Abstract, 2013, Invited

  
• Computational and Physiological Approaches to the Primate Anxiety Connectome

  Ken-ichi Amemori

  computational connectome: SPP-2041 Meeting, 29 Mar. 2022, Invited

  
• 霊長類の不安と意欲を制御する前帯状皮質膝下部と 腹側線条体回路

  雨森賢一

  Kyoto University Primate Research Institute Joint Usage Workshop, 04 Mar. 2022, Invited

  

Books and Other Publications

• beyond smart life 好奇心が駆動する社会

  Joint work, 第2章６ 不安回路と社会貢献の関係性

  日本経済新聞出版, Aug. 2020

  
• ブレインサイエンス・レビュー = Brain science review

  ブレインサイエンス振興財団, Joint work, 接近回避葛藤下の意思決定を制御する前帯状皮質－ストリオソーム回路

  クバプロ, 2020

  

Awards

• 01 Jun. 2006

  National Parkinson foundation, Lynn Diamond Fellow
• 01 Jun. 2002

  Institute of Systems, Control & Information Engineers, Best paper award
• 31 Mar. 1999

  Nara Institute of Science and Technology, Best student award

External funds: Kakenhi

• 予測符号化による情動制御：霊長類情動システムの階層性と制御

  Grant-in-Aid for Transformative Research Areas (A)

  Transformative Research Areas, Section (IV)

  Kyoto University

  雨森 賢一

  From 01 Apr. 2026, To 31 Mar. 2028, Adopted

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-26H01169/
• Identification of Macaque Brain Networks Involved in Anxiety Generation and Development of Non-invasive Stimulation Techniques

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 51:Brain sciences and related fields

  Kyoto University

  Ken-ichi Amemori

  From 09 Jul. 2021, To 31 Mar. 2025, Project Closed

  不安障害;大脳基底核;前帯状皮質;情動;感情の制御;うつ病;マカクザル;脳の大規模ネットワーク;神経生理学;非侵襲刺激;磁気共鳴画像法;超音波刺激法;認知神経科学;微小電気刺激法;線条体;fMRI

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K19428/
• Neural basis of active inference

  Grant-in-Aid for Transformative Research Areas (B)

  Transformative Research Areas, Section (IV)

  Kyoto University

  Ken-ichi Amemori

  From 23 Aug. 2021, To 31 Mar. 2024, Project Closed

  不安障害;大脳基底核;前帯状皮質;情動;感情の制御;うつ病;マカクザル;脳の大規模ネットワーク;神経解剖学;意思決定;予測符号化;接近回避葛藤;神経生理学;認知神経科学;計算論的神経科学;線条体;自由エネルギー原理;能動的推論;化学遺伝学;霊長類;DREADD;ストリオソーム

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-21H05169/
• 不安障害と回復期にみられる霊長類辺縁皮質－線条体の神経振動の同期現象

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Complex systems

  Kyoto University

  雨森 賢一

  From 01 Apr. 2020, To 31 Mar. 2022, Discontinued

  霊長類;ベータ振動;不安障害;意思決定;線条体;腹内側前頭前皮質;接近回避葛藤;神経生理学;認知神経科学;計算論的神経科学;大脳基底核;辺縁皮質;腹側被蓋野;ドーパミン

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-20H05469/
• 悲観的な価値判断を引き起こす霊長類側坐核－ドーパミン経路の機能解明

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Complex systems

  Kyoto University

  雨森 賢一

  From 01 Apr. 2020, To 31 Mar. 2022, Discontinued

  霊長類;DREADD;不安障害;意思決定;線条体;腹側淡蒼球;接近回避葛藤;腹側線条体;神経生理学;認知神経科学;計算論的神経科学;大脳基底核;側坐核;腹側被蓋野;化学遺伝学;マカクザル

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-20H05063/
• 不安障害の制御を目指した霊長類ストリオソーム関連回路の機能解明

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51020:Cognitive and brain science-related

  Kyoto University

  雨森 賢一

  From 01 Apr. 2020, To 31 Mar. 2025, Granted

  神経生理学;認知神経科学;不安障害;大脳基底核;線条体;マカクザル;霊長類;DREADD;意思決定;ストリオソーム;接近回避葛藤;化学遺伝学;計算論的神経科学;側坐核

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H03555/
• Identification of primate neural circuits that is related to social anxiety

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 51:Brain sciences and related fields

  Kyoto University

  Ken-ichi Amemori

  From 29 Jun. 2018, To 31 Mar. 2021, Project Closed

  不安障害;社会不安障害;全般性不安障害;線条体;社会性;神経生理学;マカクザル;社会ランク;化学遺伝学;インタラクトーム解析;認知神経科学;大脳基底核;側坐核;霊長類;意思決定;ドーパミン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K19497/
• 霊長類ドーパミン経路における価値判断を操作するスパイクパターンの同定

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Kyoto University

  雨森 賢一

  From 01 Apr. 2018, To 31 Mar. 2020, Project Closed

  霊長類;DREADD;不安障害;意思決定;側坐核;腹側被蓋野;接近回避葛藤;化学遺伝学;線条体;不安と葛藤;ドーパミン;情動;大脳基底核

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-18H05131/
• 悲観的な価値判断と相関する大脳皮質ー線条体における新たなベータ波

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Kyoto University

  雨森 賢一

  From 01 Apr. 2018, To 31 Mar. 2020, Project Closed

  霊長類;ベータ振動;不安障害;意思決定;線条体;ドーパミン;情動;コヒーレンス解析;大脳基底核;神経振動;ベータ波

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-18H04943/
• 霊長類の側坐核-腹側被蓋野経路の選択的制御による価値判断のメカニズム解明

  Grant-in-Aid for Research Activity Start-up

  Kyoto University

  雨森 賢一

  From 25 Aug. 2017, To 31 Mar. 2019, Project Closed

  大脳基底核;霊長類;強迫性障害;常同行動;意思決定;価値判断;脳・神経;脳神経疾患;神経科学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H06771/
• 行動決定に伴う脳内競合メカニズムの実験的・理論的解明

  Grant-in-Aid for Young Scientists (B)

  Hokkaido University

  雨森 賢一

  From 01 Apr. 2004, To 31 Mar. 2007, Project Closed

  意思決定;前頭前皮質;ニューロン活動記録法;ニューロンモデル;学習;報酬期待;競合;ワーキングメモリ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16700270/
• 光計測による左右脳機能分化の発達過程の解明

  Grant-in-Aid for Exploratory Research

  Hokkaido University

  澤口 俊之

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  大脳半球の左右差;脳機能分化;光トポグラフィー;大脳発達過程;就学前児童;前頭連合野;ワーキングメモリ;近赤外線分光法;ワーキングメモリー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15650124/
• Model-based reinforcement learning : brain implementation and engineering applications

  Grant-in-Aid for Scientific Research (B)

  Nara Institute of Science and Technology

  Shin ISHII

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  強化学習;前頭前野;計算論的神経科学;ロボット制御;ベイズ推定;非侵襲脳計測;システム同定;モデル同定;ロボット;ペイズ学習;意思決定;視覚追従制御;ワーキングメモリ;逐次モンテカルロ法;機能的磁気共鳴図, reinforcement learning;prefrontal cortex;computational neuroscience;robot control;Bayesian inference;non-invasive brain activity measurement;system identification

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15300102/
• 前頭連合野機能コラムのダイナミクスに対するモノアミン修飾作用の解明

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Hokkaido University

  澤口 俊之

  From 01 Apr. 2003, To 31 Mar. 2005, Project Closed

  ワーキングメモリ;前頭連合野;機能コラム;ドーパミン;脳スライス;高速光学測定法;膜電位感受性色素;セルアンサンブル;前頭前野;ノルアドレナリン;相互相関分析;マルチニューロン記録;イオントフォレシス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15029202/
• The role of monoamines in reward processing in the prefrontal cortex

  Grant-in-Aid for Scientific Research (B)

  HOKKAIDO UNIVERSITY

  Toshiyuki SAWAGUCHI

  From 01 Apr. 2001, To 31 Mar. 2005, Project Closed

  前頭連合野;報酬;サル;ドーパミン;行動切り替え;局所投与;モノアミン;眼球運動, Prefrontal cortex;Reward;Monkey;Dopamine;Shifting of behavior;Local injection;Monoamine;Oculomotor

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13410021/
• ワーキングメモリのセルアンサンブルにおけるモノアミンの役割

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Hokkaido University

  澤口 俊之

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  ワーキングメモリ;前頭前野;ドーパミン;ノルアドレナリン;相互相関分析;マルチニューロン記録;イオントフォレシス;セルアンサンブル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13041001/
• Generative adversarial brain: a comprehensive study of multi-agent learning by natural and artificial intelligence

  Grant-in-Aid for Scientific Research (S)

  Broad Section J

  Kyoto University

  石井 信

  From 27 Apr. 2022, To 31 Mar. 2027, Granted

  計算神経科学;敵対生成ネットワーク;意思決定;モデルベース強化学習;知能ロボティクス;敵対生成脳;強化学習;ロボティクス;計算論的神経科学;敵対的生成ネットワーク;Artificial Intelligence;Meta learning;Agile robotics;Artificial intelligence

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H04998/
• 敵対生成脳の計算理論と人工知能応用

  Grant-in-Aid for Scientific Research (A)

  Medium-sized Section 61:Human informatics and related fields

  Kyoto University

  石井 信

  From 01 Apr. 2022, To 31 Mar. 2023, Discontinued

  敵対生成脳;計算論的神経科学;知能ロボティクス;深層強化学習;脳型人工知能;計算神経科学;非侵襲脳活動計測;サル神経生理;ベイズ学習

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H00534/
• Frontiers in brain and life sciences on active information gain in an uncertain environment

  Grant-in-Aid for Transformative Research Areas (B)

  Transformative Research Areas, Section (IV)

  Nagoya University

  Fumitaka Osakada

  From 23 Aug. 2021, To 31 Mar. 2024, Project Closed

  自由エネルギー原理;予測符号化;能動的推論;限定合理性;David Marr;神経回路;葛藤;認知;データ駆動的解読;数理モデル;ベイズ推定;知覚;意思決定;好奇心;AI;新FEP理論;神経科学;情報獲得

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-21H05167/
• Predictive Coding in Anxiety Circuit: Hierachical Network in Primate Limbic System

  Grant-in-Aid for Transformative Research Areas (A)

  Transformative Research Areas, Section (IV)

  Kyoto University

  雨森 賢一

  From 01 Apr. 2024, To 31 Mar. 2026, Granted

  神経生理学;マカクザル;計算論的神経科学;予測符号化;脳の大規模ネットワーク;認知神経科学

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-24H02163/
• 不安障害の制御を目指した霊長類ストリオソーム関連回路の機能解明

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51020:Cognitive and brain science-related

  Kyoto University

  雨森 賢一

  From 01 Apr. 2024, To 31 Mar. 2026, Granted

  神経生理学;認知神経科学;不安障害;大脳基底核;線条体;化学遺伝学;マカクザル;前帯状皮質;ストリオソーム;接近回避葛藤;意思決定;霊長類;DREADD;計算論的神経科学;側坐核

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K20319/
• Genetic Approaches to Analyzing Primate Anxiety Networks: Toward Understanding and Controlling Anxiety and Depression

  Grant-in-Aid for Scientific Research (B)

  Basic Section 46030:Function of nervous system-related

  Kyoto University

  雨森 賢一

  From 01 Apr. 2025, To 31 Mar. 2028, Granted

  神経生理学;認知神経科学;不安障害;線条体;脳の大規模ネットワーク

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25K02377/

External funds: others

• 不安障害の制御を目指した霊長類大脳基底核回路の機能解明

  武田科学振興財団 生命科学研究助成

  From 01 Sep. 2020, To 31 Aug. 2021

  雨森 賢一
• 気分障害の解消を目指した霊長類側坐核の神経操作技術の確立

  2019年度　住友財団　基礎科学研究助成

  From 01 Nov. 2019, To 31 Oct. 2020

  雨森　賢一
• 不安や悲観的判断に関わる霊長類側坐核経路の機能解明

  Ｈ２９上原記念生命科学財団・研究助成金

  From 09 Feb. 2018, To 31 Jan. 2019

  雨森　賢一
• 霊長類の悲観的な価値判断の固執を引き起こす神経メカニズムの解明

  第４９回　内藤記念科学奨励金・研究助成

  From 29 Dec. 2017, To 30 Nov. 2018

  雨森　賢一
• ドーパミン経路制御による意思決定の解明

  ブレインサイエンス振興財団　第３２回研究助成

  From 01 Jun. 2018, To 31 May 2019

  雨森　賢一

Education

Teaching subject(s)

• From 01 Apr. 2023, To 31 Mar. 2024

  システム情報論特別セミナー

  通年,情報学研究科

Participation in PhD Defense

• Computational Modeling and Neural Mechanisms of Hierarchical Inference and Decision-making in Partially-observable Environments

  KATAYAMA RISA, Graduate School of Informatics, Sub-chief Examiner

  24 Sep. 2024

Administration

Faculty management (title, position)

• From 01 Apr. 2024, To 31 Mar. 2026

  動物実験委員会　委員

Academic, Social Contribution

Committee Memberships

• From Jan. 2024, To Present

  Consulting Editor, Cognitive, Affective and Behavioral Neuroscience

Academic Contribution

• Reviewer, Grant-in-Aid for Scientific Research (KAKENHI), Category B and S

  Supervision (editorial)

  Japan Society for the Promotion of Science (JSPS), From Jan. 2026, To Jan. 2026

  
• NIPS workshop 2020

  Planning, management, etc., Panel moderator

  From 14 Sep. 2020, To 15 Sep. 2020

  
• The 43rd Annual Meeting of the Japan Neuroscience Society

  Planning, management, etc., Panel moderator

  From Jul. 2020

  
• AsCNP/JSNP/JSCNP 2019

  Panel moderator

  From 12 Oct. 2019

  

Social Contribution

• The Japan Association for Chemical Innovation (JACI)

  Consultant

  The Japan Association for Chemical Innovation (JACI), 未来社会プラットフォームⅡ, From Sep. 2020, To Apr. 2021