Basic Information

Email Address

• Email Address

  igarashi.taichi.2skyoto-u.ac.jp

Professional Memberships

• 日本癌学会
• 日本分子生物学会

Academic Degree

• 30 Sep. 2024

  北里大学博士（理学）
• 10 Mar. 2022

  北里大学修士（理学）

Academic Resume (Undergraduate School/Majors)

• 北里大学, 理学部生物科学科, 卒業

Research History

• From Apr. 2025, To Present

  京都大学, 大学院生命科学研究科附属放射線生物研究センター, 特任助教
• From Oct. 2024, To Mar. 2025

  Kyoto University, Graduate School of Biostudies, Program-Specific Assistant Professor

ID,URL

• J-Global ID

  202401007873674725

• Researcher number

  31014623

• External link

  https://www.rbc.kyoto-u.ac.jp/genome_stress/

researchmap URL

• https://researchmap.jp/taiigara

Research

Research Interests

• DNA replication
• ゲノム安定性
• PrimPol
• KRAS
• クロマチンダイナミクス
• 転写
• がん

Research Areas

• Life sciences, Tumor biology
• Life sciences, Cell biology

Papers

• 

  Replication stress tolerance confers the evolution of cancer genome

  Taichi Igarashi; Takaaki Yasuhara; Bunsyo Shiotani

  Radiation Biology Research Communications, Mar. 2025, Peer-reviewed, Invited, Lead author, Corresponding author

  
• PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells

  Kimiyoshi Yano; Megumi Kato; Syoju Endo; Taichi Igarashi; Ryoga Wada; Takashi Kohno; Astrid Zimmermann; Heike Dahmen; Frank T. Zenke; Bunsyo Shiotani

  Cell Death Discovery, 28 Jan. 2025, Peer-reviewed

  
• Tolerance of Oncogene-Induced Replication Stress: A Fuel for Genomic Instability

  Taichi Igarashi; Kimiyoshi Yano; Syoju Endo; Bunsyo Shiotani

  Cancers, 17 Oct. 2024, Peer-reviewed, Invited, Lead author

  
• An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress.

  Taichi Igarashi; Marianne Mazevet; Takaaki Yasuhara; Kimiyoshi Yano; Akifumi Mochizuki; Makoto Nishino; Tatsuya Yoshida; Yukihiro Yoshida; Nobuhiko Takamatsu; Akihide Yoshimi; Kouya Shiraishi; Hidehito Horinouchi; Takashi Kohno; Ryuji Hamamoto; Jun Adachi; Lee Zou; Bunsyo Shiotani

  Nature communications, 17 Aug. 2023, Peer-reviewed, Lead author

  

Misc.

• 北里大学夏休み子ども実験教室

  五十嵐, 太一

  北里大学教職課程センター教育研究, 25 Dec. 2018

  
• 北里大学夏休み子ども実験教室

  五十嵐, 太一; 伊東, 慶子

  北里大学教職課程センター教育研究, 22 Dec. 2017

  

Academic, Social Contribution

Committee Memberships

• From May 2024, To Present

  広報委員会ワーキンググループ, 日本癌学会