Basic Information

Professional Memberships

• JAPANESE SOCIETY FOR RADIATION ONCOLOGY
• THE JAPAN SOCIETY OF APPLIED PHYSICS
• JAPAN SOCIETY OF MEDICAL PHYSICS
• 日本CT技術学会
• American Association of Medical Physics

Academic Degree

• Master (Engineering)(Kyoto University)
• Ph.D. (Engineering)(Kyoto University)

Academic Resume (Graduate Schools)

• Kyoto University, Nuclear Engineering, Engineering, 修了
• Kyoto University, Nuclear Engineering, Engineering, 修了

Academic Resume (Undergraduate School/Majors)

• Tokyo University of Science, Physics, Science, 卒業

High School

• High School

  興南高等学校

Research History

• From Apr. 2023, To Present

  Kyoto Katsura Hospital, 放射線治療科, Medical Physicist
• From Apr. 2018, To Present

  Kyoto Univeristy Hospital, Department of Radiation Oncology, Assistant Professor, Medical Physicist
• From Apr. 2017, To Mar. 2023

  Nagahama City Hospital, Department of Radiation Oncology, Medical Physicist
• From Apr. 2017, To Mar. 2019

  Mitsubishi Kyoto Hospital, Department of Radiation Oncology, Medical Physicist

Profile

• Profile

  理工系出身の医学物理士として，放射線治療の臨床・研究・教育に携わっています．

Language of Instruction

• Japanese
• English

ID,URL

• ORCID ID

  0000-0003-4059-7932

• J-Global ID

  201801003039649877

• Researcher number

  80826008

• External link

  http://medicalphysics.hs.med.kyoto-u.ac.jp/

Website(s) (URL(s))

• http://medicalphysics.hs.med.kyoto-u.ac.jp/

researchmap URL

• https://researchmap.jp/hiraku-iramina

Research

Research Topics, Overview of the research

• Research Topics

  ①kV-X線による放射線治療の高精度化に関する研究
  ②マルチエナジーCT及びマルチエナジーコーンビームCTの放射線治療への応用に関する研究

Research Interests

• Online adaptive radiotherapy
• Cone-beam CT
• Multi-energy Imaging
• Cancer
• Radiation Tehrapy
• Medical Physics

Research Areas

• Life sciences, Radiology
• Energy, Quantum beam science, Medical Physics
• Life sciences, Radiology, Medical Physics

Papers

• Multi-institutional questionnaire-based survey on online adaptive radiotherapy performed using commercial systems in Japan in 2023.

  Hiraku Iramina; Masato Tsuneda; Hiroyuki Okamoto; Noriyuki Kadoya; Nobutaka Mukumoto; Masahiko Toyota; Junichi Fukunaga; Yukio Fujita; Naoki Tohyama; Hiroshi Onishi; Mitsuhiro Nakamura

  Radiological physics and technology, 19 Jul. 2024

  
• Influence of dose calculation algorithms on the helical diode array using volumetric‐modulated arc therapy for small targets

  Tomohiro Ono; Hideaki Hirashima; Takanori Adachi; Hiraku Iramina; Takahiro Fujimoto; Megumi Uto; Mitsuhiro Nakamura; Takashi Mizowaki

  Journal of Applied Clinical Medical Physics, 16 Feb. 2024

  
• Organ‐contour‐driven auto‐matching algorithm in image‐guided radiotherapy

  Yukako Kishigami; Mitsuhiro Nakamura; Hiroyuki Okamoto; Ayaka Takahashi; Hiraku Iramina; Makoto Sasaki; Kohei Kawata; Hiroshi Igaki

  Journal of Applied Clinical Medical Physics, 23 Nov. 2023

  
• Unifying gamma passing rates in patient-specific QA for VMAT lung cancer treatment based on data assimilation.

  Tomohiro Ono; Takanori Adachi; Hideaki Hirashima; Hiraku Iramina; Noriko Kishi; Yukinori Matsuo; Mitsuhiro Nakamura; Takashi Mizowaki

  Physical and engineering sciences in medicine, 20 Jun. 2024

  
• Applications of artificial intelligence for machine- and patient-specific quality assurance in radiation therapy: current status and future directions.

  Tomohiro Ono; Hiraku Iramina; Hideaki Hirashima; Takanori Adachi; Mitsuhiro Nakamura; Takashi Mizowaki

  Journal of radiation research, 27 May 2024

  
• Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study).

  Noriko Kishi; Masahiro Yoneyama; Hiroyuki Inoo; Minoru Inoue; Hiraku Iramina; Akiyoshi Nakakura; Tomohiro Ono; Hideaki Hirashima; Takanori Adachi; Norimasa Matsushita; Makoto Sasaki; Takahiro Fujimoto; Mitsuhiro Nakamura; Yukinori Matsuo; Takashi Mizowaki

  Radiation oncology (London, England), 08 Mar. 2024

  Access this paper :

  
• [JSMP Executive Committee Program: Medical Physics Roundtable for Young Researchers].

  Sodai Tanaka; Hiraku Iramina; Masashi Kinjo; Masato Tsuneda; Hideaki Hirashima; Koki Kasamatsu; Tomohiro Ohta; Shuta Ogawa; Masaki Kato; Madoka Sakai

  Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2023

  
• Development of a prediction model for target positioning by using diaphragm waveforms extracted from CBCT projection images.

  Yuta Sakurai; Shintaro Ambo; Mitsuhiro Nakamura; Hiraku Iramina; Yusuke Iizuka; Takamasa Mitsuyoshi; Yukinori Matsuo; Takashi Mizowaki

  Journal of applied clinical medical physics, 06 Aug. 2023

  
• Quantification of six-degree-of-freedom motion during beam delivery in spine stereotactic body radiotherapy using intra-irradiation cone-beam computed tomography imaging technique.

  Hiraku Iramina; Mitsuhiro Nakamura; Kiyonao Nakamura; Takahiro Fujimoto; Takashi Mizowaki

  Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Jun. 2023

  
• Identification of reproducible radiomic features from on-board volumetric images: A multi-institutional phantom study.

  Takanori Adachi; Mitsuhiro Nakamura; Hiraku Iramina; Kazushige Matsumoto; Yoshitomo Ishihara; Hidenobu Tachibana; Shogo Kurokawa; SangYong Cho; Kazunori Tanaka; Kenta Fukumoto; Tomohiro Nishiyama; Satoshi Kito; Takashi Mizowaki

  Medical physics, 18 Mar. 2023

  
• Automatic measurement of beam‐positioning accuracy at off‐isocenter positions

  Tomohiro Ono; Takahisa Kido; Mitsuhiro Nakamura; Hiraku Iramina; Ryo Kakino; Takashi Mizowaki

  Journal of Applied Clinical Medical Physics, 24 Nov. 2022

  
• Potential utility of cone-beam CT-guided adaptive radiotherapy under end-exhalation breath-hold conditions for pancreatic cancer.

  Ayaka Ogawa; Mitsuhiro Nakamura; Hiraku Iramina; Michio Yoshimura; Takashi Mizowaki

  Journal of applied clinical medical physics, 31 Oct. 2022

  
• Development of independent dose verification plugin using Eclipse scripting API for brachytherapy.

  Dejun Zhou; Mitsuhiro Nakamura; Yohei Sawada; Tomohiro Ono; Hideaki Hirashima; Hiraku Iramina; Takanori Adachi; Takahiro Fujimoto; Takashi Mizowaki

  Journal of radiation research, 09 Oct. 2022

  
• [Introduction of Young Researchers' Association of Medical Physics and Questionnaire Survey on Medical Physics Education and Medical Physics Training System in Japan for Young Researchers in 2021].

  Hiraku Iramina; Masashi Kinjo; Sodai Tanaka; Masato Tsuneda; Hideaki Hirashima

  Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2022

  
• Dosiomic feature comparison between dose-calculation algorithms used for lung stereotactic body radiation therapy

  Takanori Adachi; Mitsuhiro Nakamura; Ryo Kakino; Hideaki Hirashima; Hiraku Iramina; Yusuke Tsuruta; Tomohiro Ono; Nobutaka Mukumoto; Yuki Miyabe; Yukinori Matsuo; Takashi Mizowaki

  Radiological Physics and Technology, 24 Jan. 2022

  
• Photoneutron-induced damage reduction for cardiac implantable electronic devices using neutron-shielding sheets in high-energy X-ray radiotherapy: A phantom study

  Ryo Kakino; Mitsuhiro Nakamura; Naonori Hu; Hiraku Iramina; Hiroki Tanaka; Yoshinori Sakurai; Takashi Mizowaki

  Physica Medica, Sep. 2021

  
• Highly hypofractionated intensity-modulated radiation therapy for nonmetastatic prostate cancer with a simultaneous integrated boost to intraprostatic lesions: a planning study.

  Ryo Ashida; Kiyonao Nakamura; Rihito Aizawa; Hiraku Iramina; Kenji Takayama; Mitsuhiro Nakamura; Takashi Mizowaki

  Japanese journal of radiology, 05 Aug. 2021

  
• Actual delivered dose calculation on intra-irradiation cone-beam computed tomography images: a phantom study.

  Hiraku Iramina; Mitsuhiro Nakamura; Takashi Mizowaki

  Physics in medicine and biology, 25 Nov. 2020, Peer-reviewed

  
• Image quality evaluation of intra‐irradiation cone‐beam computed tomography acquired during one‐ and two‐arc prostate volumetric‐modulated arc therapy delivery: A phantom study

  Hiraku Iramina; Ayaka Kitamura; Mitsuhiro Nakamura; Takashi Mizowaki

  Journal of Applied Clinical Medical Physics, 16 Nov. 2020, Peer-reviewed, Lead author

  
• Quantification and correction of the scattered X-rays from a megavoltage photon beam to a linac-mounted kilovoltage imaging subsystem

  Hiraku Iramina; Mitsuhiro Nakamura; Yuki Miyabe; Nobutaka Mukumoto; Tomohiro Ono; Hideaki Hirashima; Takashi Mizowaki

  BJR|Open, Nov. 2020, Peer-reviewed, Lead author

  
• Direct measurement and correction of both megavoltage and kilovoltage scattered x-rays for orthogonal kilovoltage imaging subsystems with dual flat panel detectors.

  Hiraku Iramina; Mitsuhiro Nakamura; Takashi Mizowaki

  Journal of applied clinical medical physics, 25 Jul. 2020, Peer-reviewed

  
• Improvement of prediction and classification performance for gamma passing rate by using plan complexity and dosiomics features.

  Hideaki Hirashima; Tomohiro Ono; Mitsuhiro Nakamura; Yuki Miyabe; Nobutaka Mukumoto; Hiraku Iramina; Takashi Mizowaki

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 23 Jul. 2020, Peer-reviewed

  
• Radiotherapy planning techniques to reduce lung irradiation in head and neck cancer patients with mediastinal involvement.

  Mitsue Kawamura; Michio Yoshimura; Mitsuhiro Nakamura; Yoshitomo Ishihara; Nobutaka Mukumoto; Hideaki Hirashima; Hiraku Iramina; Masahiro Hiraoka; Takashi Mizowaki

  Radiological physics and technology, Jun. 2020, Peer-reviewed

  
• Independent calculation-based verification of volumetric-modulated arc therapy-stereotactic body radiotherapy plans for lung cancer.

  Tomohiro Ono; Takamasa Mitsuyoshi; Takashi Shintani; Yusuke Tsuruta; Hiraku Iramina; Hideaki Hirashima; Yuki Miyabe; Mitsuhiro Nakamura; Yukinori Matsuo; Takashi Mizowaki

  Journal of applied clinical medical physics, 11 May 2020, Peer-reviewed

  Access this paper :

  
• Performance evaluation of a newly developed three-dimensional model-based global-to-local registration in prostate cancer.

  Mitsuhiro Nakamura; Megumi Nakao; Hideaki Hirashima; Hiraku Iramina; Takashi Mizowaki

  Journal of radiation research, 23 Oct. 2019, Peer-reviewed

  Access this paper :

  
• Prediction of dosimetric accuracy for VMAT plans using plan complexity parameters via machine learning.

  Tomohiro Ono; Hideaki Hirashima; Hiraku Iramina; Nobutaka Mukumoto; Yuki Miyabe; Mitsuhiro Nakamura; Takashi Mizowaki

  Medical physics, Sep. 2019, Peer-reviewed

  
• Quality assurance of non-coplanar, volumetric-modulated arc therapy employing a C-arm linear accelerator, featuring continuous patient couch rotation.

  Hideaki Hirashima; Mitsuhiro Nakamura; Yuki Miyabe; Nobutaka Mukumoto; Tomohiro Ono; Hiraku Iramina; Takashi Mizowaki

  Radiation oncology (London, England), 11 Apr. 2019, Peer-reviewed

  Access this paper :

  
• Filter-based energy-resolved X-ray computed tomography with a clinical imager

  Tsai Tien-Hsiu; Hamaguchi Takumi; Iramina Hiraku; Nakamura Mitsuhiro; Kanno Ikuo

  JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, 01 Feb. 2019, Peer-reviewed

  
• [Department of Radiation Oncology and Image-Applied Therapy at Kyoto University Hospital].

  Yuki Miyabe; Nobutaka Mukumoto; Tomohiro Ono; Hiraku Iramina; Hideaki Hirashima; Mitsuhiro Nakamura

  Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2019, Peer-reviewed

  
• Treatment planning based on water density image generated using dual-energy computed tomography for pancreatic cancer with contrast-enhancing agent: Phantom and clinical study.

  Ohira S; Yagi M; Iramina H; Karino T; Washio H; Ueda Y; Miyazaki M; Koizumi M; Teshima T

  Medical physics, Nov. 2018, Peer-reviewed

  
• Optimization of training periods for the estimation model of three-dimensional target positions using an external respiratory surrogate

  Hiraku Iramina; Mitsuhiro Nakamura; Yusuke Iizuka; Takamasa Mitsuyoshi; Yukinori Matsuo; Takashi Mizowaki; Ikuo Kanno

  Radiation Oncology, 19 Apr. 2018, Peer-reviewed

  
• Metal artifact reduction by filter-based dual-energy cone-beam computed tomography on a bench-top micro-CBCT system: concept and demonstration.

  Iramina H; Hamaguchi T; Nakamura M; Mizowaki T; Kanno I

  Journal of radiation research, Apr. 2018, Peer-reviewed

  Access this paper :

  
• Quantification of the kV X-ray imaging dose during real-time tumor tracking and from three- and four-dimensional cone-beam computed tomography in lung cancer patients using a Monte Carlo simulation.

  Mitsuhiro Nakamura; Yoshitomo Ishihara; Yukinori Matsuo; Yusuke Iizuka; Nami Ueki; Hiraku Iramina; Hideaki Hirashima; Takashi Mizowaki

  Journal of radiation research, 01 Mar. 2018, Peer-reviewed

  
• 

  Effective Atomic Number Measurement with Energy-Resolved Computed Tomography Using Two-Dimensional “transXend” Detector

  Hiraku Iramina

  International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, Feb. 2018, Peer-reviewed

  
• The accuracy of extracted target motion trajectories in four-dimensional cone-beam computed tomography for lung cancer patients

  Hiraku Iramina; Mitsuhiro Nakamura; Yusuke Iizuka; Takamasa Mitsuyoshi; Yukinori Matsuo; Takashi Mizowaki; Masahiro Hiraoka; Ikuo Kanno

  RADIOTHERAPY AND ONCOLOGY, Oct. 2016, Peer-reviewed

  
• A novel method for dose distribution registration using fiducial marks made by a megavoltage beam in film dosimetry for intensity-modulated radiation therapy quality assurance

  Shinichi Nakayama; Hajime Monzen; Yuuichi Oonishi; Rika Mizote; Hiraku Iramina; Souichirou Kaneshige; Takashi Mizowaki

  PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, Jun. 2015, Peer-reviewed

  
• [A Survey Towards Standardization of Dosimetric Verification in Intensity-modulated Radiation Therapy].

  Nakamura M; Iramina H; Takamiya M; Ono T; Akimoto M; Mukumoto N; Ishihara Y; Utsunomiya S; Shiinoki T; Miyabe Y; Sato S; Monzen H

  Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2014, Peer-reviewed

  

Misc.

• 動体追尾肺定位放射線治療における呼吸性移動に伴う体内留置マーカー間非同期性による標的照準不確かさの検討

  松元聖弥; 中村光宏; 椋本宜学; 小野智博; 伊良皆拓; 平島英明; 足立孝則; 宮部結城; 松尾幸憲; 溝脇尚志

  日本放射線腫瘍学会高精度放射線外部照射部会学術大会プログラム・抄録集, 2023

  
• 放射線治療学分野におけるAI技術の活用

  中村 光宏; 伊良皆 拓; 平島 英明; 柿野諒; 足立孝則

  Rad Fan 特集1 画像診断領域におけるAIはココまで来ている, Jun. 2020, Lead author

  
• AAPM TG 158: Measurement and calculation of doses outside the treated volume from external-beam radiation therapy.

  中村光宏; 伊良皆拓

  Rad Fan 海外文献を読み解く, Dec. 2019, Lead author

  
• Accuracy of Target Motion Trajectory in 4-Dimensional Cone Beam Computed Tomography for Lung Cancer Patients

  H. Iramina; M. Nakamura; Y. Iizuka; T. Mitsuyoshi; Y. Matsuo; T. Mizowaki; M. Hiraoka; I. Kanno

  INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Oct. 2016

  
• 強度変調放射線治療における線量検証の標準化に向けた調査研究

  中村 光宏; 伊良皆 拓; 高宮 大義; 小野 智博; 秋元 麻未; 椋本 宜学; 石原 佳知; 宇都宮 悟; 椎木 健裕; 宮部 結城; 佐藤 清香; 門前 一

  医学物理, Mar. 2015

  
• フラットパネル検出器を用いたエネルギー分解コンピュータ断層撮影法の検証

  伊良皆拓; 桑原潤一; 山下良樹; 木村優志; 北原理; 小川剛史; 船引綾乃; 叶井絵梨; 神野郁夫; 伊藤秋男; 門前一; 平岡真寛

  応用物理学会春季学術講演会講演予稿集(CD-ROM), 2014

  

Presentations

• 

  キロボルトX線による放射線治療の高精度化

  伊良皆 拓

  沖縄医学物理勉強会 放射線治療における品質管理, 19 Jan. 2019

  
• 京都大学における呼吸性移動対策の臨床と研究

  伊良皆 拓

  12 Jan. 2019, Invited

  
• 放射線治療におけるキロボルトX線を 用いた腫瘍位置検出技術の開発

  伊良皆 拓

  第51回日本保健物理学会, 30 Jun. 2018, Invited

  

Awards

• 14 Jun. 2020

  Japan Society of Medical Physics, President's Award (Silver)
• 15 Apr. 2018

  Japan Society of Medical Physics, CyPos Award
• 15 Apr. 2018

  Japan Society of Medical Physics, English Presentation Award
• 16 Sep. 2017

  Japan Society of Medical Physics, Young Investigator Award
• 04 Aug. 2016

  Japan Society of Applied Physics, Best Research Award
• 12 Apr. 2016

  Japan Society of Medical Physics, CyPos Award
• 11 Dec. 2014

  Kangenkon, Best Research Award
• 25 Oct. 2014

  Asia-Oceania Congress of Medical Physics, Best Oral Presentation Award

External funds: Kakenhi

• Developement of new imaging method to improve cure rate of radiation therapy for intractable cancers

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  Hiraku Iramina

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  マルチエナジー撮像;コーンビームCT;即時適応放射線治療;メタルアーチファクト低減;高画質化;同時曝射;高精度放射線治療;アダプティブ放射線治療;実効原子番号;疑似単色X線画像

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K17265/
• 放射線治療開始までの時間短縮が可能かつ体内状況に適応する次世代放射線治療法の開発

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  伊良皆 拓

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  即時適応放射線治療;コーンビームCT;Ethos;同時曝射;治療計画CTが不要;コミッショニング;適応放射線治療;待機時間の短縮

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K15844/

External funds: others

• Acquisition of actual target positions and delivered dose based on cone-beam computed tomography of a specific respiratory phase acquired during gated volumetric-modulated arc therapy

  Varian Medical Systems, Varian Research Grant

  From 01 Mar. 2022, To 28 Feb. 2024

  中村　光宏

  伊良皆　拓
• エネルギー分解コンピュータ断層撮影法によるコントラスト向上と造影剤副作用低減の可能性

  原子力関係科学技術の基礎的研究の動向調査委員会

  From 01 Jan. 2015, To 31 Dec. 2015

  伊良皆拓
• Visualizing implanted fiducials in pancreas on 2D kV and 3D CBCT image acquired during concurrent MV beam irradiation

  Varian Research Grant (分担)

  From 01 Jan. 2019, To 31 Jul. 2021

  中村光宏

Academic, Social Contribution

Committee Memberships

• From Oct. 2019, To Present

  顧問, 放射線治療人工知能研究会
• From Apr. 2018, To Present

  代議員, 日本医学物理学会
• From Apr. 2020, To Mar. 2022

  Secretary, Japan Society of Applied Physics

Social Contribution

• 夢へのバトン（職業紹介）

  Lecturer

  夢へのバトン（職業紹介）, From 22 Feb. 2024

  
• 第14回放射線医学オープンスクール

  Official expert, Planner, Logistic support

  医用原子力財団, 第14回放射線医学オープンスクール, From 02 Sep. 2022

  
• 第13回放射線医学オープンスクール

  Panelist, Planner, Logistic support, Report author

  医用原子力財団, 第13回放射線医学オープンスクール, From 16 Aug. 2021, To 30 Aug. 2021

  
• 夢へのバトン

  Lecturer

  沖縄県興南中学校, 夢へのバトン（職業紹介）, From 12 Nov. 2019

  
• 第12回放射線医学オープンスクール

  Official expert, Planner, Logistic support, Report author

  医用原子力財団, 第12回放射線医学オープンスクール, From 22 Aug. 2019, To 23 Aug. 2019

  
• 第11回放射線医学オープンスクール

  Planner, Logistic support

  医用原子力財団, 第11回放射線医学オープンスクール, From 20 Aug. 2018, To 21 Aug. 2018