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Kengaku, Mineko

Institute for Advanced Study Professor

Kengaku, Mineko
list
    Last Updated :2022/06/24

    Basic Information

    Affiliated programs (koza)

    • Graduate School of Biostudies, 統合生命科学専攻(神経発生学) 生体構造解析学講座, 教授

    Academic Degree

    • Master of Science(The Univesity of Tokyo)
    • Doctor of Medical Science(The Univesity of Tokyo)

    Research History

    • From Apr. 2017, To Present
      Kyoto University, 高等研究院 物質-細胞統合システム拠点, 教授
    • From Nov. 2012, To Mar. 2017
      Kyoto University, 物質−細胞統合システム拠点, 教授
    • From Oct. 2008, To Oct. 2012
      Kyoto University, 物質−細胞統合システム拠点, 准教授
    • From Jan. 2004, To Sep. 2008
      RIKEN, チームリーダー
    • From Jan. 2002, To Dec. 2003
      京都大学 大学院, 理学研究科・講師
    • From Dec. 1997, To Dec. 2001
      Kyoto University, Graduate School of Science, 助手
    • From 1995, To 1997
      Cliff Tabin Lab, Harvard Medical School, ポスドク
    • From 1995
      東京大学医学系研究科第一基礎医学専攻, 博士課程修了
    • From 1991
      東京大学理学系研究科動物学専攻, 修士課程修了
    • From 1989
      The University of Tokyo, Faculty of Science, Department of Biological Sciences, 卒業

    Language of Instruction

    • English

    ID,URL

    researchmap URL

    list
      Last Updated :2022/06/24

      Research

      Research Topics, Overview of the research

      • Research Topics

        Mechanisms regulating neuronal motility during the formation of the brain cortex
      • Overview of the research

        The mammalian central nervous system (CNS) is comprised of 10 billions of neurons that are orderly arranged in laminar cortices and nuclei for integration into specific neural circuits. Newborn neurons directionally migrate from the site of birth to their destination within the cortex or nucleus, and then arborize well-patterned dendrites and axons to contact with their specific synaptic counterparts.
        The major goal of our research is to clarity the mechanisms regulating directional migration and process arborization of developing CNS neurons with special reference to the cytoarchitectonic formation of the mammalian cerebellar cortex.

      Research Interests

      • 接線移動
      • クラスリン
      • シナプス
      • 細胞骨格
      • 選択輸送
      • 内顆粒層(IGL)
      • 細胞分化
      • 小脳
      • 外顆粒層(EGL)
      • 極性輸送
      • 細胞間相互作用
      • 細胞移動
      • 核移動
      • 神経細胞移動
      • Wntシグナル
      • 顆粒細胞
      • プルキンエ細胞
      • Pax6
      • DNER
      • 樹状突起
      • 小脳顆粒細胞
      • 中枢神経系ニューロン
      • 細胞極性
      • 包括脳ネットワーク
      • 統合脳・分子脳科学
      • 統合脳・神経回路機能

      Research Areas

      • Life sciences, Neuroscience - general
      • Life sciences, Neuroscience - general

      Papers

      • ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking
        Mitsuhiro Nakato; Naoko Shiranaga; Maiko Tomioka; Hitomi Watanabe; Junko Kurisu; Mineko Kengaku; Naoko Komura; Hiromune Ando; Yasuhisa Kimura; Noriyuki Kioka; Kazumitsu Ueda
        Journal of Biological Chemistry, 2021, Peer-reviewed
      • βIII spectrin controls the planarity of Purkinje cell dendrites by modulating perpendicular axon-dendrite interactions
        Kazuto Fujishima; Junko Kurisu; Midori Yamada; Mineko Kengaku
        Development, 15 Dec. 2020, Peer-reviewed
      • Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.
        Yotaro Ochi; Ayana Kon; Toyonori Sakata; Masahiro M Nakagawa; Naotaka Nakazawa; Masanori Kakuta; Keisuke Kataoka; Haruhiko Koseki; Manabu Nakayama; Daisuke Morishita; Tatsuaki Tsuruyama; Ryunosuke Saiki; Akinori Yoda; Rurika Okuda; Tetsuichi Yoshizato; Kenichi Yoshida; Yusuke Shiozawa; Yasuhito Nannya; Shinichi Kotani; Yasunori Kogure; Nobuyuki Kakiuchi; Tomomi Nishimura; Hideki Makishima; Luca Malcovati; Akihiko Yokoyama; Kengo Takeuchi; Eiji Sugihara; Taka-Aki Sato; Masashi Sanada; Akifumi Takaori-Kondo; Mario Cazzola; Mineko Kengaku; Satoru Miyano; Katsuhiko Shirahige; Hiroshi I Suzuki; Seishi Ogawa
        Cancer discovery, Jun. 2020, Peer-reviewed
      • Mechanical Regulation of Nuclear Translocation in Migratory Neurons.
        Naotaka Nakazawa; Mineko Kengaku
        Frontiers in cell and developmental biology, 2020
      • Dynamic Contact Guidance of Myoblasts by Feature Size and Reversible Switching of Substrate Topography: Orchestration of Cell Shape, Orientation, and Nematic Ordering of Actin Cytoskeletons
        Philipp Linke; Ryo Suzuki; Akihisa Yamamoto; Masaki Nakahata; Mineko Kengaku; Takahiro Fujiwara; Takuya Ohzono; Motomu Tanaka
        Langmuir, 11 Jun. 2019, Peer-reviewed
      • Local traction force in the proximal leading process triggers nuclear translocation during neuronal migration
        Hiroki Umeshima; Ken-ichi Nomura; Shuhei Yoshikawa; Marcel Hörning; Motomu Tanaka; Shinya Sakuma; Fumihito Arai; Makoto Kaneko; Mineko Kengaku
        Neuroscience Research, May 2019, Peer-reviewed
      • Multiple roles of the actin and microtubule-regulating formins in the developing brain.
        K. Kawabata Galbraith; M. Kengaku
        Neurosci Res., 2019
      • MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells
        Kelly Kawabata Galbraith; Kazuto Fujishima; Hiroaki Mizuno; Sung-Jin Lee; Takeshi Uemura; Kenji Sakimura; Masayoshi Mishina; Naoki Watanabe; Mineko Kengaku
        Cell Reports, Jul. 2018, Peer-reviewed
      • Nesprins and opposing microtubule motors generate a point force that drives directional nuclear motion in migrating neurons
        You Kure Wu; Hiroki Umeshima; Junko Kurisu; Mineko Kengaku
        Development, 01 Mar. 2018, Peer-reviewed
      • Dynamic Interaction Between Microtubules and the Nucleus Regulates Nuclear Movement During Neuronal Migration.
        Y.K. Wu; M. Kengaku
        J Exp Neurosci., 2018
      • Cytoskeletal control of nuclear migration in neurons and non-neuronal cells.
        M. Kengaku
        Proc Jpn Acad Ser B Phys Biol Sci., 2018
      • Dendritic Self-Avoidance and Morphological Development of Cerebellar Purkinje Cells.
        K. Fujishima; K. Kawabata Galbraith; M. Kengaku
        Cerebellum, 2018
      • Surface chemistry for cytosolic gene delivery and photothermal transgene expression by gold nanorods
        Hirotaka Nakatsuji; Kelly Kawabata Galbraith; Junko Kurisu; Hiroshi Imahori; Tatsuya Murakami; Mineko Kengaku
        Scientific Reports, Dec. 2017, Peer-reviewed
      • Thyroid Hormone Induces PGC-1 alpha during Dendritic Outgrowth in Mouse Cerebellar Purkinje Cells
        Tetsu Hatsukano; Junko Kurisu; Kansai Fukumitsu; Kazuto Fujishima; Mineko Kengaku
        FRONTIERS IN CELLULAR NEUROSCIENCE, May 2017, Peer-reviewed
      • Mitochondrial fission protein Drp1 regulates mitochondrial transport and dendritic arborization in cerebellar Purkinje cells
        Kansai Fukumitsu; Tetsu Hatsukano; Azumi Yoshimura; John Heuser; Kazuto Fujishima; Mineko Kengaku
        MOLECULAR AND CELLULAR NEUROSCIENCE, Mar. 2016, Peer-reviewed
      • Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates
        Yuta Takano; Tomohiro Numata; Kazuto Fujishima; Kazuaki Miyake; Kazuya Nakao; Wesley David Grove; Ryuji Inoue; Mineko Kengaku; Shigeyoshi Sakaki; Yasuo Mori; Tatsuya Murakami; Hiroshi Imahori
        CHEMICAL SCIENCE, 2016, Peer-reviewed
      • Control of Spontaneous Ca2+Transients Is Critical for Neuronal Maturation in the Developing Neocortex
        Yuki Bando; Katsumasa Irie; Takushi Shimomura; Hiroki Umeshima; Yuki Kushida; Mineko Kengaku; Yoshinori Fujiyoshi; Tomoo Hirano; Yoshiaki Tagawa
        Cerebral Cortex, Jan. 2016, Peer-reviewed
      • ECHO-liveFISH: in vivo RNA labeling reveals dynamic regulation of nuclear RNA foci in living tissues
        Ikumi Oomoto; Asuka Suzuki-Hirano; Hiroki Umeshima; Yong-Woon Han; Hiroyuki Yanagisawa; Peter Carlton; Yoshie Harada; Mineko Kengaku; Akimitsu Okamoto; Tomomi Shimogori; Dan Ohtan Wang
        NUCLEIC ACIDS RESEARCH, Oct. 2015, Peer-reviewed
      • Cerebellar granule cells are predominantly generated by terminal symmetric divisions of granule cell precursors
        Kie Nakashima; Hiroki Umeshima; Mineko Kengaku
        DEVELOPMENTAL DYNAMICS, Jun. 2015, Peer-reviewed
      • Synergistic Action of Dendritic Mitochondria and Creatine Kinase Maintains ATP Homeostasis and Actin Dynamics in Growing Neuronal Dendrites
        Kansai Fukumitsu; Kazuto Fujishima; Azumi Yoshimura; You Kure Wu; John Heuser; Mineko Kengaku
        JOURNAL OF NEUROSCIENCE, Apr. 2015, Peer-reviewed
      • Differentiation of Apical and Basal Dendrites in Pyramidal Cells and Granule Cells in Dissociated Hippocampal Cultures
        You Kure Wu; Kazuto Fujishima; Mineko Kengaku
        PLOS ONE, Feb. 2015, Peer-reviewed
      • Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations
        Masahiro Kumeta; Jamie L. Gilmore; Hiroki Umeshima; Masaaki Ishikawa; Shin-ichiro Kitajiri; Tsuneyoshi Horigome; Mineko Kengaku; Kunio Takeyasu
        GENES TO CELLS, Apr. 2014, Peer-reviewed
      • An evolutionarily conserved protein CHORD regulates scaling of dendritic arbors with body size
        Kohei Shimono; Kazuto Fujishima; Takafumi Nomura; Masayoshi Ohashi; Tadao Usui; Mineko Kengaku; Atsushi Toyoda; Tadashi Uemura
        SCIENTIFIC REPORTS, Mar. 2014, Peer-reviewed
      • Differential roles of cyclin-dependent kinase 5 in tangential and radial migration of cerebellar granule cells
        Hiroki Umeshima; Mineko Kengaku
        MOLECULAR AND CELLULAR NEUROSCIENCE, Jan. 2013, Peer-reviewed
      • The Effects of Neurological Disorder-Related Codon Variations of ABCA13 on the Function of the ABC Protein
        Maiko Tomioka; Yoshinobu Toda; Junko Kurisu; Yasuhisa Kimura; Mineko Kengaku; Kazumitsu Ueda
        BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Dec. 2012, Peer-reviewed
      • Principles of branch dynamics governing shape characteristics of cerebellar Purkinje cell dendrites
        Kazuto Fujishima; Ryota Horie; Atsushi Mochizuki; Mineko Kengaku
        DEVELOPMENT, Sep. 2012, Peer-reviewed
      • Remodeling of Monoplanar Purkinje Cell Dendrites during Cerebellar Circuit Formation
        Megumi Kaneko; Kazuhiko Yamaguchi; Mototsugu Eiraku; Motohiko Sato; Norio Takata; Yoshimoto Kiyohara; Masayoshi Mishina; Hajime Hirase; Tsutomu Hashikawa; Mineko Kengaku
        PLOS ONE, May 2011, Peer-reviewed
      • Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation
        Nobunari Sasaki; Junko Kurisu; Mineko Kengaku
        MOLECULAR AND CELLULAR NEUROSCIENCE, Dec. 2010, Peer-reviewed
      • Polarized targeting of DNER into dendritic plasma membrane in hippocampal neurons depends on endocytosis
        Junko Kurisu; Tetsuko Fukuda; Seisuke Yokoyama; Tomoo Hirano; Mineko Kengaku
        JOURNAL OF NEUROCHEMISTRY, Jun. 2010, Peer-reviewed
      • Computational modeling of dendritic tiling by diffusible extracellular suppressor
        Kohei Shimono; Kaoru Sugimura; Mineko Kengaku; Tadashi Uemura; Atsushi Mochizuki
        GENES TO CELLS, Feb. 2010, Peer-reviewed
      • Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly
        Masami Yamada; Yuko Yoshida; Daisuke Mori; Takako Takitoh; Mineko Kengaku; Hiroki Umeshima; Keizo Takao; Tsuyoshi Miyakawa; Makoto Sato; Hiroyuki Sorimachi; Anthony Wynshaw-Boris; Shinji Hirotsune
        NATURE MEDICINE, Oct. 2009, Peer-reviewed
      • Receptor type protein tyrosine phosphatase zeta-pleiotrophin signaling controls endocytic trafficking of DNER that regulates neuritogenesis
        Nobuna Fukazawa; Seisuke Yokoyama; Mototsugu Eiraku; Mineko Kengaku; Nobuaki Maeda
        MOLECULAR AND CELLULAR BIOLOGY, Jul. 2008, Peer-reviewed
      • Microtubule-based nuclear movement occurs independently of centrosome positioning in migrating neurons
        Hiroki Umeshima; Tomoo Hirano; Mineko Kengaku
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2007, Peer-reviewed
      • Targeted disruption of Sept3, a heteromeric assembly partner of Sept5 and Sept7 in axons, has no effect on developing CNS neurons
        Kazuto Fujishima; Hiroshi Kiyonari; Junko Kurisu; Tomoo Hirano; Mineko Kengaku
        JOURNAL OF NEUROCHEMISTRY, Jul. 2007, Peer-reviewed
      • Membrane-proximal region of glutamate receptor delta 2 subunit is critical for long-term depression and interaction with protein interacting with C kinase 1 in a cerebellar Purkinje neuron
        S Yawata; H Tsuchida; M Kengaku; T Hirano
        JOURNAL OF NEUROSCIENCE, Apr. 2006, Peer-reviewed
      • Impaired cerebellar functions in mutant mice lacking DNER
        A Tohgo; M Eiraku; T Miyazaki; E Miura; S Kawaguchi; M Nishi; M Watanabe; T Hirano; M Kengaku; H Takeshima
        MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2006, Peer-reviewed
      • Generation of cerebellar neuron precursors from embryonic stem cells
        HL Su; K Muguruma; M Matsuo-Takasaki; M Kengaku; K Watanabe; Y Sasai
        DEVELOPMENTAL BIOLOGY, Feb. 2006, Peer-reviewed
      • DNER acts as a neuron-specific Notch ligand during Bergmann glial development
        M Eiraku; A Tohgo; K Ono; M Kaneko; K Fujishima; T Hirano; M Kengaku
        NATURE NEUROSCIENCE, Jul. 2005, Peer-reviewed
      • Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin
        Yasuyuki Shima; Mineko Kengaku; Tomoo Hirano; Masatoshi Takeichi; Tadashi Uemura
        Developmental Cell, Aug. 2004, Peer-reviewed
      • Dual phases of migration of cerebellar granule cells guided by axonal and dendritic leading processes
        K Kawaji; H Umeshima; M Eiraku; T Hirano; M Kengaku
        MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2004, Peer-reviewed
      • Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons
        Minami, I; M Kengaku; PS Smitt; R Shigemoto; T Hirano
        EUROPEAN JOURNAL OF NEUROSCIENCE, Mar. 2003, Peer-reviewed
      • Delta/Notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like ReDeat-cont ining protein T ryeted to dendrites of developing and adult central nervous system neurons
        M Eiraku; Y Hirata; H Takeshima; T Hirano; M Kengaku
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2002, Peer-reviewed
      • Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum
        T Yamasaki; K Kawaji; K Ono; H Bito; T Hirano; N Osumi; M Kengaku
        DEVELOPMENT, Aug. 2001, Peer-reviewed
      • Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation
        R Haraguchi; K Suzuki; R Murakami; M Sakai; M Kamikawa; M Kengaku; K Sekine; H Kawano; S Kato; N Ueno; G Yamada
        DEVELOPMENT, Jun. 2000, Peer-reviewed
      • FGF signaling and the anterior neural induction in Xenopus
        Hongo, I; M Kengaku; H Okamoto
        DEVELOPMENTAL BIOLOGY, Dec. 1999, Peer-reviewed
      • Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud
        M Kengaku; J Capdevila; C Rodriguez-Esteban; J De La Pena; RL Johnson; JCI Belmonte; CJ Tabin
        SCIENCE, May 1998, Peer-reviewed
      • Expression of Wnt and Frizzled genes during chick limb bud development
        M Kengaku; Twombly, V; C Tabin
        COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1997, Peer-reviewed
      • BFGF AS A POSSIBLE MORPHOGEN FOR THE ANTEROPOSTERIOR AXIS OF THE CENTRAL-NERVOUS-SYSTEM IN XENOPUS
        M KENGAKU; H OKAMOTO
        DEVELOPMENT, Sep. 1995, Peer-reviewed
      • BASIC FIBROBLAST GROWTH-FACTOR INDUCES DIFFERENTIATION OF NEURAL-TUBE AND NEURAL CREST LINEAGES OF CULTURED ECTODERM CELLS FROM XENOPUS-GASTRULA
        M KENGAKU; H OKAMOTO
        DEVELOPMENT, Dec. 1993, Peer-reviewed
      • MULTIPLE MESSENGER-RNA SPECIES OF CHOLINE-ACETYLTRANSFERASE FROM RAT SPINAL-CORD
        M KENGAKU; H MISAWA; T DEGUCHI
        MOLECULAR BRAIN RESEARCH, Apr. 1993, Peer-reviewed
      • ROLE OF FIBRONECTIN IN THE INHIBITORY EFFECT OF TGF-BETA ON CHOLINE-ACETYLTRANSFERASE ACTIVITY IN COCULTURES OF SPINAL-CORD NEURONS AND MYOTUBES
        M KENGAKU; A KAWATA; S KAWASHIMA; M NAKANE
        DEVELOPMENTAL BRAIN RESEARCH, Aug. 1991, Peer-reviewed
      • EXPRESSION OF CHOLINE-ACETYLTRANSFERASE ACTIVITY IN A COCULTURE OF SPINAL-CORD AND SKELETAL-MUSCLE CELLS IS INHIBITED BY MYOGENIC DIFFERENTIATION INHIBITORS
        M KENGAKU; S KAWASHIMA; M NAKANE
        DEVELOPMENTAL BRAIN RESEARCH, Jun. 1991, Peer-reviewed
      • THE PREDOMINANT PROTEIN IN AN APHID ENDOSYMBIONT IS HOMOLOGOUS TO AN ESCHERICHIA-COLI HEAT-SHOCK PROTEIN
        E HARA; T FUKATSU; K KAKEDA; M KENGAKU; C OHTAKA; H ISHIKAWA
        SYMBIOSIS, 1990, Peer-reviewed

      Misc.

      • 【メカノバイオロジー】力学環境依存的な細胞の機能発現 脳発生に寄与するニューロン遊走のメカノバイオロジー
        中澤 直高; 見学 美根子
        生体の科学, Aug. 2019
      • 小脳顆粒細胞前駆細胞の分裂様と運命決定の生細胞イメージング解析
        中島輝恵; 中島輝恵; 梅嶋宏樹; 見学美根子; 見学美根子
        日本分子生物学会年会プログラム・要旨集(Web), 2013
      • ニューロンの細胞移動と脳皮質形成のメカニズム (特集 脳形成を司るニューロン移動の時空間的制御)
        見学美根子
        実験医学, 2007, Invited
      • 神経細胞移動における中心体、核移動のダイナミクス
        梅嶋宏樹; 見学美根子
        実験医学, 2007, Invited
      • 小脳ニューロン・グリアの細胞形態形成を制御する細胞間相互作用 (特集 脳の発生分化と回路形成)
        永樂元次; 見学美根子
        神経研究の進歩, Feb. 2005, Invited
      • 小脳顆粒細胞の移動--直角な方向転換のメカニズム (神経回路の機能発現のメカニズム) -- (神経細胞の分化と移動)
        見学美根子; 梅嶋宏樹
        蛋白質核酸酵素, Feb. 2004, Invited
      • 神経細胞の移動
        見学美根子
        脳神経科学, 2003, Invited
      • 顆粒細胞の移動と小脳の層形成
        見学美根子
        実験医学増刊号「脳のパターン形成、神経ネットワーク、神経再生と臨床応用」, 2002, Invited
      • 中枢神経系の発生と機能発現におけるWntシグナルの役割 (特集 Wntシグナルと形態形成)
        見学美根子
        細胞工学, Nov. 2000, Invited
      • WNT3aとWNT7aは同じシグナル伝達経路を介さない:ニワトリ肢芽形成におけるWNTファミリ-分子の役割
        見学美根子
        細胞工学, Sep. 1998, Invited
      • 成長因子受容体と脊椎動物神経系の発生・分化(特集 イオンチャンネルとレセプター 生理と病態)
        本郷育子; 見学美根子; 岡本治正
        神経研究の進歩, 1998
      • 神経誘導・形態形成の分子メカニズム (特集:神経誘導・分化・回路形成最前線)
        岡本治正; 見学美根子; 本郷育子
        蛋白質核酸酵素, May 1996, Invited
      • 初期発生における神経分化多様性の起源(特集 脳の発生と分化)
        岡本治正; 見学美根子; 本郷育子
        神経研究の進歩, 1995, Invited

      Presentations

      • Multiple engines driving nuclear migration in neurons during brain development.
        Mineko Kengaku
        RIMS Workshop Mathematical Mechanobiology, 14 Jul. 2021, Invited
      • Neuronal migration in 3D brain tissue.
        見学美根子
        第14回ニッチ脳神経脈管カンファレンス, 30 Aug. 2020, Invited
      • Nuclear Migration in 3D Brain Tissue Driven by Cytoskeletal Forces.
        You Kure Wu; Chuying Zhou; Hiroki Umeshima; Naotaka Nakazawa; Mineko Kengaku
        20th LSACJ2019-International Conference on Interdisciplinary Life Sciences 2019, 24 Nov. 2019, International Conference on Interdisciplinary Life Sciences 2019, Invited
      • Cytoskeletal forces driving nuclear migration in developing neurons.
        Mineko Kengaku; You Kure Wu; Naotaka Nakazawa; Gianluca Grenci
        The 10th IBRO World Congress of Neuroscience IBRO2019, 22 Sep. 2019, International Brain Research Organization & Federation of Asian-Oceanian Neuroscience Societies, Invited
      • Cell-extrinsic control of dendritic tree patterns of the cerebellar Purkinje cell.
        Kazuto Fujishima; Kelly Kawabata-Galbraith; Mineko Kengaku
        Current Trends and Future Directions of Synapse-Circuit Plasticity Research, 04 Sep. 2019, US-Japan Brain Research Cooperative Program, Invited
      • Mechanisms of force generation by cytoskeletal motors during nuclear migration of developing neurons.
        You Wu; Chuying Zhou; Hiroki Umeshima; Gianluca Grenci; Naotaka Nakazawa; Mineko Kengaku
        第52回日本発生生物学会年会, 17 May 2019, 日本発生生物学会, Invited
      • Dynamics and mechanics of axon-dendrite wiring geometries in the developing brain.
        Kazuto Fujishima; Midori Yamada; Junko Kurisu; Mineko Kengaku
        第52回日本発生生物学会年会, 15 May 2019, 日本発生生物学会, Invited
      • High resolution imaging of cytoskeletal dynamics in developing neurons.
        Mineko Kengaku
        Carl Zeiss Microscopy Seminar, 04 Feb. 2019, Carl Zeiss, Invited
      • Cytoskeletal control of neuronal migration in the developing brain.
        Mineko Kengaku
        The SPIRITS International Symposium-2019 Regulation of cell fate and disease treatment, 29 Jan. 2019, iCeMS, Kyoto University, Invited
      • High-resolution Imaging of Neuronal Migration in the Developing Brain.
        Mineko Kengaku
        Kyoto University-UCLA International Symposium/25th iCeMS International Symposium “Harnessing Physical Forces for Medical Applications- The Convergence of Physics, Nanomaterials, Cell Biology and Cancer Research”, 15 Nov. 2018, iCeM Kyoto University, CNSI of UCLA, Invited
      • Cytoskeletal control of nuclear movement during neuronal migration.
        Mineko Kengaku
        Capital Medical University Symposium ‘A New Era of Molecular and Cellular Neuroscience’, 10 Oct. 2018, Capital Medical University, Beijing, China, Invited
      • Studying cell dynamics in the developing brain using in vitro reconstruction systems.
        見学 美根子
        第41回日本神経科学大会, 27 Jul. 2018, 日本神経科学学会, Invited
      • Molecular mechanism of cytoarchitecture formation of cerebellar neurons.
        Kazuto Fujishima; Mineko Kengaku
        The 3rd Japan-US Technical Information Exchange Forum Blast Injury (JUFBI 2018), 09 May 2018, the National Defense Medical College Japan (NDMC), Invited
      • Developing neurons on the move – dynamic sculpting of one-of-a-kind dendritic trees.
        見学 美根子
        BSI Retreat 2017, 31 Oct. 2017, 理研BSI, Invited
      • Molecular basis of the mechanical force driving neuronal migration in the developing brain.
        Mineko Kengaku; You Kure Wu; Hiroki Umeshima
        Joint Meeting of the German and Japanese Societies of Developmental Biologists, 18 Mar. 2017, the German (GfE) and Japanese Societies of Developmental Biologists (JSDB), Invited
      • Cytoskeletal control of dynamic motility of the nucleus during neuronal migration.
        MIneko Kengaku; You K Wu; Hiroki Umeshima
        The 39th Annual Meeting of the Japan Neuroscience Society, 22 Jul. 2016, 日本神経科学学会, Invited
      • The molecular nature of the force driving nuclear transport during neuronal migration.
        Mineko Kengaku
        Swiss-Kyoto Joint Symposium on Life Science -Understanding the Cellular and Molecular Mechanisms of ht Robustness and Plasticity of Life-, 13 Jun. 2016, 学際・国際・人際融合事業「知の越境」融合チーム研究プロジェクト, Invited
      • Mechanics underlying cell architecture formation in the developing brain.
        Mineko Kengaku
        Center for Functional Connectomics Seminar, Korea Institute of Science and Technology, 06 Apr. 2016, Korea Institute of Science and Technology, Invited
      • Nuclear dynamics during neuronal migration in the developing brain.
        Mineko Kengaku
        I.M.A. workshop on neural imaging in neuroscience, 21 Mar. 2016, iCeMS Kyoto University, the MRC(Medical Research Council), Invited
      • Molecular mechanism underlying the axon-dendrite wiring topology.
        Kelly Kawabata; Kazuto Fujishima; Mineko Kengaku
        The 2nd Symposium of Neuroscience Network in Kobe, 19 Feb. 2016, 神戸大学大学院医学研究科, Invited
      • Measurement of the Force Driving Nuclear Transport during Neuronal Migration in the Developing Brain.
        Umeshima, You Kure Wu; Mineko Kengaku
        iCeMS International Symposium ‘Hierarchical Dynamics in Soft Materials and Biological Matter’, 26 Sep. 2015, iCeMS, Kyoto University, Invited
      • The contact-geometry of axons and dendrites in the cerebellar cortex.
        Mineko Kenagku; Kazuto Fujishima
        The 38th Annual Meeting of the Japan Neuroscience Society, 28 Jul. 2015, 日本神経科学学会, Invited
      • Energy homeostasis in growing dendrites of cerebellar Purkinje cells.
        MIneko Kengaku; Kansai Fukumitsu; Kazuto Fujishima; Tetsu Hatsukano
        the 120th Annual Meeting of The Japanese Association of Anatomists, the 92nd Annual Meeting of The Physiological Society of Japan, 22 Mar. 2015, 日本解剖学会・日本生理学会, Invited
      • Energy homeostasis in growing dendrites.
        Mineko Kengaku
        2015 Dendrites: Molecules, Structure & Function, Gordon Research Conference, 17 Mar. 2015, Gordon Research Conference, Invited
      • Mechanics of nuclear migration in developing neurons.
        Mineko Kengaku
        The 18th iCeMS International Symposium, The 15th International Membrane Research Forum, 04 Mar. 2015, iCeMS, Kyoto University, Invited
      • Energy homeostasis in Purkinje cell dendrites - Live-imaging analysis of the formation and maintenance of dendritic tree shape in developing CNS neurons.
        Mineko Kengaku
        OIST Mini Symposium: Recent Findings on the Cerebellar Microcircuitry, 28 Jan. 2015, OIST, Computational Neuroscience Unit, Invited
      • Mechanical basis of cell motility control in the developing brain.
        Mineko Kengaku
        25th 2014 International Symposium on Micro-NanoMechatronics and Human Science (MHS2014), 11 Nov. 2014, Micro-NanoMechatronics and Human Science, Invited
      • Live-imaging analysis of the formation and maintenance of dendritic tree shape in developing CNS neurons.
        Mineko Kengaku
        The 37th NAITO CONFERENCE, 16 Jul. 2014, 公益財団法人内藤記念科学振興財団, Invited
      • Dynamics and Mechanisms of Branch Pattern Formation in Neuronal Dendrites.
        Mineko Kengaku
        Symposium: Three Domains of Life “from molecule to organism”, 29 Mar. 2014, Takeyasu Lab, Kyoto Unievrsity, Invited
      • Principles and mechanisms of branch pattern formation governing dendrite growth dynamics.
        Mineko Kengaku
        KU-NTU Joint Symposium, 19 Dec. 2013, Kyoto University and National Taiwan University, Invited
      • In vitroライブイメージングによるプルキンエ細胞樹状突起分岐形成のダイナミクス解析
        見学美根子
        日本顕微鏡学会 分子・細胞動態イメージング研究部会平成25年度研究会「複雑なシステムをイメージングにより解明する」, 05 Oct. 2013, 日本顕微鏡学会, Invited
      • Live-imaging analysis of neurons in vitro toward mechanistic understanding of cell motility in developing brains.
        Mineko Kengaku
        The 3rd Japanese-German University Presidents’ Conference 2013 “Challenges and Perspectives in Promoting Young Researchers” Work Group Meetings, 12 Sep. 2013, HeKKSaGOn University Consortium, Invited
      • Mechanisms and dynamics sculpting cerebellar Purkinje cell dendrites.
        Mineko Kengaku
        The 28th International Prize for Biology Commemorative Symposium ‘Neurogenesis throughout Life’, 28 Nov. 2012, International Prize for Biology/JSPS, Invited
      • Principles and mechanisms governing dendrite growth dynamics in the cerebellar Purkinje cell.
        Mineko Kengaku
        Japan-U.S. Brain Research Cooperation Program Information Exchange Seminar Program FY2012, 10 Oct. 2012, US-JAPAN Brain Research Cooperative Program (BRCP), Invited
      • Principles branch dynamics governing spatial patterns in Purkinje cell dendrites.
        見学美根子; 藤島和人; 福光甘斎; 堀江亮太; 望月敦史
        第35回日本神経科学大会 日本・中国神経科学学会合同シンポジウム:アジア神経科学の最前線, 20 Sep. 2012, 日本神経科学学会, Invited
      • 小脳皮質における細胞形態分化の分子機構とダイナミクス
        見学美根子
        第2回神経科学と構造生物学の融合, 22 Nov. 2011, 大阪大学蛋白質研究所セミナー包括脳ネットワーク研究会, Invited
      • Dynamics of branch patterning in neuronal dendrites.
        Mineko Kengaku
        Cancer Area Meeting of Kyoto University Medical School, 21 Apr. 2011, Kyoto University Medical School, Invited
      • Mechanisms regulating spatial distribution of Purkinje cell dendrites.
        見学美根子; 藤島和人; 福光甘斎; 堀江亮太; 望月敦史
        第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会, 30 Mar. 2011, 日本生理学会、日本解剖学会, Invited
      • Cellular and molecular dynamics of nuclear movement in neuronal migration.
        Mineko Kengaku
        RBC・NIRS International Symposium “Centrosome in DNA Damage Response and Diseases”, 22 Oct. 2010, RBC・NIRS, Invited
      • プログラム非依存的な小脳ニューロン樹状突起パターンの制御
        見学美根子
        京都大学再生医科学研究所第1回生命科学セミナー, 07 Sep. 2010, 京都大学再生医科学研究所, Invited
      • Dynamics and mechanisms of branch pattern formation of Purkinje cell dendrites.
        見学美根子; 藤島和人; 堀江亮太; 望月淳史
        第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会合同大会, 04 Sep. 2010, 日本神経科学学会, Invited
      • 小脳顆粒細胞の遊走におけるオルガネラ移動のダイナミクス
        見学美根子
        神経組織の成長・再生・移植研究会第25回学術集会, 21 May 2010, 神経組織の成長・再生・移植研究会, Invited
      • Refinement of connectivity by remodeling of dendrite conformation in Purkinje cells.
        Mineko Kengaku
        第32回日本神経科学大会, 16 Sep. 2009, 日本神経科学学会, Invited
      • Dynamics and mechanisms of branch patterning of neuronal dendrites in the brain.
        Mineko Kengaku
        The forth iCeMS International Symposium, 27 May 2009, iCeMS, Kyoto University, Invited
      • Program-independent control of dendrite branching in CNS neurons.
        Mineko Kengaku
        日本学術振興会 回折構造生物第169委員会 第27回研究会, 28 Oct. 2008, 日本学術振興会 回折構造生物第169委員会, Invited
      • Activity-dependent control of flat arborization of Purkinje cell dendrites.
        Mineko Kengaku
        Neuroscience Graduate Program at UCSF 2008-2009 Formal Seminar, 24 Sep. 2008, UCSF, Invited
      • Mecanisms of dendrite arborization of the cerebellar Purkinje cell.
        見学美根子; 金子めぐみ; 藤島和人; 永樂元次; 端川勉
        第31回日本神経科学大会 Neurosciense 2008, 09 Jul. 2008, 日本神経科学学会, Invited
      • 小脳皮質形成を担うニューロン移動と樹状突起伸展のダイナミクス
        見学美根子
        国立遺伝学研究所 The 1239th Biological Symposium, 12 May 2008, 国立遺伝学研究所, Invited
      • Activity-dependent control of flat arborization of Purkinje cell dendrites.
        Mineko Kengaku
        CDB symposium 2008 “Turning Neurons into a Nervous System”, 25 Mar. 2008, RIKEN Center for Developmental Biology, Invited
      • Mechanisms of neuronal migration
        見学美根子
        システム神経生物学スプリングスクール2008, 02 Mar. 2008, 科研費特定領域「情報統計力学の深化と展開」(DEX-SMI)、京都大学グローバルCOEプログラム、奈良先端科学技術大学院大学、日本神経回路学会, Invited
      • The mechanism of neuronal migration in the brain.
        Mineko Kengaku
        The 1st iCeMS International Symposium, 21 Feb. 2008, iCeMS, Kyoto University, Invited
      • Cellular and Molecular Dynamics of Nuclear Movement in Neuronal Migration.
        Mineko Kengaku
        The 6th PICOWER-RIKEN Neuroscience Symposium, 08 Nov. 2007, The Picower Institute for Learning and Memory, RIKEN, Invited
      • DNER-Notch signaling in the postnatal CNS.
        見学美根子; 金清華; 藤島和人
        第30回日本神経科学大会、第50回日本神経化学学会大会、第17回日本神経回路学会大会合同大会 Neuro2007, 10 Sep. 2007, 日本神経科学学会、日本神経回路学会、日本神経化学会, Invited
      • 小脳皮質発生におけるプルキンエ細胞樹状突起のパターン形成機構
        見学美根子
        平成19年度特定領域研究「統合脳」夏のワークショップ 統合シンポジウム, 22 Aug. 2007, 文部科学省特定領域研究「統合脳」5 領域, Invited
      • 小脳皮質の層形成を司るニューロンの配置と配線のメカニズム
        見学美根子
        第47回生命科学「夏の学校2007」, 03 Aug. 2007, 生化学若い研究者の会, Invited
      • Granule Cell Migration during Corticogenesis of the Cerebellum.
        Mineko Kengaku
        Tokyo Medical and Dental University 21st Century COE Program “Brain Integration and Its Disorders” The Third International Symposium, “The Cerebellum-from Molecules to Pathogeneses-“, 17 Feb. 2007, Tokyo Medical and Dental University, Invited
      • 小脳皮質形成における顆粒細胞移動ダイナミクス
        見学美根子
        再生増殖制御学セミナー, 24 Nov. 2006, 京都大学再生医科学研究所 再生増殖制御学分野, Invited
      • Molecular and cellular kinetics of neuronal migration in the developing cerebellar cortex.
        Mineko Kengaku; Hiroki Umeshima
        20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress in conjunction with 79th Annual Meeting of the Japanese Biochemical Society and 29th Annual Meeting of the Molecular Biology Society of Japan, 18 Jun. 2006, JBS、MBSJ, Invited
      • Cell migration and process arborization during cortical lamination in the cerebellum.
        Mineko Kengaku
        Osaka-NAIST Joint COE International Symposium “Cells into Organisms-細胞から個体まで”, 17 Jun. 2006, NAIST, Invited
      • Contact-dependent regulatio of process arborization of neurons and glia by DNER-Notch signaling
        見学美根子; 永樂元次; 金清華
        第48回日本神経化学会「Molecular mechanism of neurite formation」, 28 Sep. 2005, 日本神経化学会, Invited
      • Ligand of Notch DNER regulating neuron-glia interaction during cerebellar development.
        IDAC Symposium on Vertebrate Brain Pattern Formation
        第32回加齢研シンポジウム「Vertebrate Brain Patterning特定領域研究脳のパターン形成シンポジウム」, 29 Oct. 2004, 加齢医学研究所, Invited
      • Neuron-derived Delta/Notch-like EGF-related Receptor (DNER) regulates gliogenesis in the developing mouse cerebellum.
        Mineko Kengaku
        The 10th CDB Meeting “Kobe Meeting on Vertebrate Brain Development”, 23 Jul. 2004, RIKEN CDB, Invited
      • 中枢神経系の神経・グリア突起のパターン形成を司る DNER の機能解析
        見学美根子
        第 3 回日本再生医療学会総会, 24 Mar. 2004, 日本再生医療学会, Invited
      • Contact-dependent regulation of dendrite and glial fiber arborization mediated by delta/notch-like EGF-related receptor.
        Mineko Kengaku
        The 6th Biennial Meeting of the Asian-Pacific Society for Neurochemistry, 04 Feb. 2004, the Asian-Pacific Society for Neurochemistry, Invited
      • DNER signaling regulates branching formation of dendrites and glial fibers.
        Mineko Kengaku
        Osaka University 21st century COE Program, International Symposium “Dynamics of Neural Development”, 10 Aug. 2003, Osaka University, Invited
      • 小脳顆粒細胞の二相性細胞移動のダイナミクス.
        見学美根子
        平成15年度生理学研究所研究会「神経可塑性の分子基盤」, 29 May 2003, 生理学研究所, Invited
      • 小脳顆粒細胞の方向転換期に発現する新規膜タンパク質DNERの機能解析.
        見学美根子; 永楽元次; 藤島和人
        第25回日本神経科学大会, 07 Jul. 2002, 日本神経科学学会, Invited
      • 小脳顆粒細胞の形態分化と移動を制御する内在性極性化因子の探索
        見学美根子; 山崎崇生; 永楽元次; 河路光介
        第54回日本細胞生物学会大会, 29 May 2001, 日本細胞生物学会, Invited
      • 小脳顆粒細胞の軸索伸長と細胞移動を制御する転写因子Pax6の機能
        見学美根子; 山崎崇生; 河路光介; 小野勝彦; 尾藤晴彦; 大隅典子; 平野丈夫
        第78回日本生理学会大会, 29 Mar. 2001, 日本生理学会, Invited
      • 小脳顆粒細胞の細胞極性を司るPax6の機能解析
        見学美根子; 山崎崇生; 河路光介; 小野勝彦; 尾藤晴彦; 大隅典子; 平野丈夫
        基礎生物学研究所研究会「神経系の記憶と構築III/神経系の形を決める因子」, 20 Dec. 2000, 基礎生物学研究所, Invited
      • 小脳顆粒細胞の遊走と極性化を制御するPax6の機能
        見学美根子; 山崎崇生; 河路光介; 永楽元次; 平野丈夫; 大隅典子
        第73回日本生化学会大会シンポジウム「多細胞系構築の基盤となる細胞の接着と極性化のダイナミクス」, 11 Oct. 2000, 日本生化学会, Invited
      • 小脳顆粒細胞の遊走を制御するPax6の機能解析
        見学美根子; 山崎崇生; 河路光介; 大隅典子; 平野丈夫
        第23回日本神経科学大会、第10回神経回路学会合同大会シンポジウム「脳の形成と神経細胞の移動 -分子制御のcutting edge」, 04 Sep. 2000, 日本神経科学学会、日本神経回路学会, Invited

      Books and Other Publications

      • 京大発!フロンティア生命科学
        今井猛; 見学美根子, Joint work, 11章 身体の司令塔 脳と神経.
        講談社, Mar. 2018, Not refereed
      • 脳神経化学 – 脳はいま化学の言葉でどこまで語れるか-
        梅嶋宏樹; 見学美根子, Joint work, 23章 細胞移動と脳層構造の形成 PartⅣ 脳神経系の高次機能・構造をコントロールする分子群
        化学同人, Mar. 2018, Not refereed
      • 数理解析による樹状突起分岐ダイナミクスとパターン形成原理の解明、ブレインサイエンス・レビュー2012
        見学美根子
        クバプロ/(財)ブレインサイエンス振興財団, 2012, Not refereed
      • 樹状突起極性形成に関する最近の知見 生体の科学 特集 細胞極性の制御
        藤島和人; 見学美根子
        医学書院/公益財団法人金原一郎記念医学医療振興財団, 2012, Not refereed
      • ‘Neuronal Migration’ in Encyclopedic Reference of Neuroscience
        Mineko Kengaku, Joint work, 2782-2788
        Springer-Verlag, 2007, Not refereed

      External funds: Kakenhi

      • 新生ニューロンのDNA損傷に由来する脳ゲノム不均一性の検証
        Grant-in-Aid for Challenging Research (Exploratory)
        Medium-sized Section 46:Neuroscience and related fields
        Kyoto University
        見学 美根子
        From 09 Jul. 2021, To 31 Mar. 2023, Granted
        小脳顆粒細胞;ニューロン遊走;DNA損傷;ゲノム不均一性;NGS解析
      • Interplay of developmental clock and extracellular environment in brain formation
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        影山 龍一郎
        From 01 Apr. 2021, To 31 Mar. 2022, Granted
        神経発生;発生時計;神経幹細胞;細胞外環境;大脳構築
      • Molecular mechanism of chromatin protection by planned DNA breaks in the developing brain
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        見学 美根子
        From 01 Apr. 2021, To 31 Mar. 2023, Granted
        DNA二重鎖切断;小脳;ニューロン遊走;DNA損傷修復;トポイソメラーゼ
      • Regulatory mechanism of neuronal migration in 3D brain tissue
        Grant-in-Aid for Scientific Research (A)
        Medium-sized Section 46:Neuroscience and related fields
        Kyoto University
        見学 美根子
        From 01 Apr. 2020, To 31 Mar. 2024, Granted
        核輸送;微小管モーター;アクトミオシン;核損傷;ライブイメージング
      • 新規素材とマイクロ加工技術で再現する脳微小空間を用いたニューロン遊走機構の解析
        Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
        Medium-sized Section 46:Neuroscience and related fields
        Kyoto University
        見学 美根子
        From 09 Oct. 2018, To 31 Mar. 2022, Granted
        メカノバイオロジー;マイクロファブリケーション;ニューロン移動;神経発生;細胞骨格;ライブイメージング
      • Molecular and dynamic basis of axon guidance by mechanical stimulation
        Grant-in-Aid for Challenging Research (Exploratory)
        Kyoto University
        MIneko Kengaku
        From 30 Jun. 2017, To 31 Mar. 2019, Project Closed
        軸索ガイダンス;ナノパターン;メカノバイオロジー;細胞密着;細胞接着
      • 脳構築における発生時計と場の連携
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        影山 龍一郎
        From 30 Jun. 2016, To 31 Mar. 2021, Granted
        神経発生;発生時計;神経幹細胞;細胞外環境;大脳構築
      • 発生脳における場の物性を制御する分子基盤
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        見学 美根子
        From 30 Jun. 2016, To 31 Mar. 2021, Granted
        発生・分化;細胞・組織;脳・神経
      • Interplay of developmental clock and extracellular environment in brain formation
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        影山 龍一郎
        From 30 Jun. 2016, To 31 Mar. 2021, Granted
        神経発生;発生時計;神経幹細胞;細胞外環境;大脳構築
      • 脳皮質の神経突起3D配列を制御する力学・分子基盤
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        見学 美根子
        From 01 Apr. 2016, To 31 Mar. 2017, Discontinued
        発生・分化;細胞・組織;脳・神経
      • Exploring the mechanical force driving nuclear migration in developing neurons
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Mineko KENGAKU
        From 01 Apr. 2015, To 31 Mar. 2017, Project Closed
        神経科学;発生・分化;細胞・組織;ライブイメージング
      • Principles of branch pattern formation in dendrites of CNS neurons
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Mineko KENGAKU
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        発生・発達・再生神経科学;樹状突起;ライブイメージング;数理モデル;細胞分化
      • Non-Equilibrium Dynamics of Cytoskeleton During Cell Migration
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Motomu Tanaka
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        生命現象の物理;形状と運動;細胞遊走;神経細胞;細胞接着;細胞骨格
      • 小脳メゾ回路編成における樹状突起リモデリングの機構
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        見学 美根子
        Project Closed
        メゾ神経回路;プルキンエ細胞;神経活動;ライブイメージング;数理解析
      • Mesoscopic neurocircuitry: towards understanding of the functional and structual basis of brain information processing
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        The University of Tokyo
        AKINAO NOSE
        From 23 Jun. 2010, To 31 Mar. 2015, Project Closed
        メゾスコピック神経回路;神経回路;光生理学;optogenetics;脳情報処理;脳計算論;機能生理学;分子遺伝学
      • 中枢神経系ニューロン樹状突起パターン形成原理の解析
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        見学 美根子
        Project Closed
        樹状突起;プルキンエ細胞;分化;リモデリング
      • 小脳皮質ニューロンの細胞移動と形態分化のメカニズム
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        見学 美根子
        Project Closed
        ニューロン移動;小脳;プルキンエ細胞;樹状突起;ダイナミクス;顆粒細胞
      • 中枢神経系ニューロン樹状突起分枝形成のダイナミクスとシグナルの解析
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        The Institute of Physical and Chemical Research
        見学 美根子
        Project Closed
        DNER;樹状突起;プルキンエ細胞;顆粒細胞;核移動
      • 細胞間シグナルによる中枢神経系ニューロン・グリア突起の分岐パターン制御機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        The Institute of Physical and Chemical Research
        見学 美根子
        Project Closed
        DNER;樹状突起;プルキンエ細胞;顆粒細胞;細胞間シグナル
      • Molecular mechanisms of dendrite branching in CNS neurons
        Grant-in-Aid for Scientific Research (B)
        RIKEN
        Mineko KENGAKU
        Project Closed
        DNER;中枢神経系ニューロン;樹状突起;選択的輸送;クラスリン;シナプス;プルキンエ細胞;細胞分化;細胞間相互作用;細胞極性;突起伸長, DNER;CNS neurons;dendrite;selective transport;clathrin;synapse;purkinie cells
      • 脳形態形成を制御する細胞移動の分子機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        The Institute of Physical and Chemical Research;Kyoto University
        見学 美根子
        Project Closed
        神経細胞移動;位置情報;小脳顆粒細胞;視床;核移動;転写因子
      • 小脳顆粒細胞の形態と移動の極性を司る細胞骨格制御因子の機能解析
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        見学 美根子
        Project Closed
        ニューロン移動;小脳顆粒細胞;先導突起;樹状突起;接線移動;放射移動;軸索;細胞極性;中枢神経系ニューロン;細胞移動;Pax6;細胞骨格
      • 小脳顆粒細胞の細胞移動に伴う骨格再編成のダイナミクスとその分子機構の解析
        Grant-in-Aid for Scientific Research on Priority Areas (C)
        Biological Sciences
        Kyoto University
        見学 美根子
        Project Closed
        細胞極性;中枢神経系ニューロン;DNER;EGF様繰返し配列;選択輸送;樹状突起;先端突起;小脳顆粒細胞
      • 小脳顆粒細胞のマイグレーションを制御する分子機構の解析
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kyoto University
        見学 美根子
        Project Closed
        ニューロン移動;小脳顆粒細胞;先導突起;樹状突起;DNER;極性輸送;細胞極性;中枢神経系ニューロン;先端突起;神経細胞移動
      • 小脳顆粒のマイグレーションを制御する分子機構の解析
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Biological Sciences
        Kyoto University
        見学 美根子
        Project Closed
        細胞極性;中枢神経系ニューロン;Pax6;細胞移動;小脳顆粒細胞
      • 中枢神経系ニューロンの分化・神経回路網形成における形態形成因子Wnt7aの機能解析
        Grant-in-Aid for Encouragement of Young Scientists (A)
        Kyoto University
        見学 美根子
        Project Closed
        細胞極性;中枢神経系ニューロン;Pax6;Wntシグナル;小脳顆粒細胞;Wnt;Frizzled
      • マウス小脳顆粒細胞の移動・細胞内構造分化の極性決定を制御する分子機構の解析
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Biological Sciences
        Kyoto University
        見学 美根子
        Project Closed
        細胞極性;中枢神経系ニューロン;Pax6;Wntシグナル;小脳顆粒細胞;小脳;顆粒細胞;外顆粒層(EGL);内顆粒層(IGL);遊走;平行線維

      External funds: others

      • 臨界期可塑性によるニューロン樹状突起形態変化と神経回路再編成の機構
        最先端・次世代研究開発支援プログラム
        From 22 Feb. 2011, To 31 Mar. 2014
        見学美根子
      list
        Last Updated :2022/06/24

        Education

        Teaching subject(s)

        • From 01 Apr. 2022, To 31 Mar. 2023
          ILAS Seminar
          Z001, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Experiments in Integrated Life Sciences
          5012, Spring, Graduate School of Biostudies, 4
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar A
          2006, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Molecular and Cell Biology I
          1016, Spring, Graduate School of Biostudies, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Course in Multicellular Network
          1030, Spring, Graduate School of Biostudies, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar D
          2009, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar B
          2007, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar D
          2009, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar C
          2008, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar B
          2007, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar A
          2006, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Cellular & Molecular Mechanisms in Neural Development and Regeneration
          1035, Spring, Graduate School of Biostudies, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar C
          2008, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Experiments in Integrated Life Sciences
          5012, Fall, Graduate School of Biostudies, 4
        • From Apr. 2009, To Sep. 2009
          Perspectives on Life Science A
          Spring, 全学共通科目
        • From Apr. 2011, To Sep. 2011
          Advanced course in life science F
          Spring, 生命科学研究科
        • From Apr. 2012, To Sep. 2012
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2009, To Sep. 2009
          生命科学研究入門
          Fall, 全学共通科目
        • From Apr. 2009, To Sep. 2009
          Advanced course in life science A
          Spring, 生命科学研究科
        • From Oct. 2012, To Mar. 2013
          Integrated Cell-Material Sciences
          Fall, 全学共通科目
        • From Apr. 2012, To Mar. 2013
          Perspectives on Life Science A
          Spring, 全学共通科目
        • From Apr. 2012, To Mar. 2013
          Integrated Cell-Material Sciences
          Fall, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2013, To Mar. 2014
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2013, To Mar. 2014
          Study of Life Science I
          Spring, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          Integrated Cell-Material Sciences
          Fall, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Cellular & Molecular Mechanisms in Neural Development and Regeneration
          Fall, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Experimental Course and Seminar l
          Year-long, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Experimental Course and Seminar 2
          Year-long, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Advanced Experiments in Integrated Life Sciences
          Year-long, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Study of Life Science I
          Spring, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Integrated Cell-Material Sciences
          Fall, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Cellular & Molecular Mechanisms in Neural Development and Regeneration
          Fall, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Study of Life Science I
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Integrated Cell-Material Sciences
          Fall, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Course in Multicellular Network
          Fall, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Introduction to Biology and Life Science
          Spring, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Cellular & Molecular Mechanisms in Neural Development and Regeneration
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Course in Multicellular Network
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar A
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar A
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar B
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar B
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar C
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar C
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar D
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar D
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar A
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar A
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar B
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar B
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar C
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar C
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar D
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar D
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Introduction to Biology and Life Science
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Cellular & Molecular Mechanisms in Neural Development and Regeneration
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Molecular and Cell Biology I
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          ILAS Seminar : Research project design using cutting-edge biotechnology
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Advanced Course in Multicellular Network
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Introduction to Biology and Life Science
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Experiments in Integrated Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Experiments in Integrated Life Sciences
          Fall, 生命科学研究科

        Participation in PhD Defense

        • マウス側脳室脈絡叢からのSonic hedgehogの分泌が側脳室脈絡叢の肥大と大脳新皮質表面積の拡大をもたらす
          KINOSHITA AKIRA, Graduate School of Biostudies, Sub-chief Examiner
          23 Mar. 2022
        • 頑健な組織形態形成を支える分子基盤の遺伝学的解析
          WADA YAYOI, Graduate School of Biostudies, Sub-chief Examiner
          23 Mar. 2022
        • 神経幹細胞活性化と細胞分化におけるbHLH型転写因子Ascl1の発現動態と機能の解析
          SUEDA RISA, Graduate School of Biostudies, Sub-chief Examiner
          24 Sep. 2021
        • Multisite phosphorylation regulates actin-binding and -bundling activities of MISP/ Caprice
          NUR DIYANA BINTI MAAROF, Graduate School of Biostudies, Sub-chief Examiner
          24 Sep. 2021

        Part-time lecturer

        • From 21 Jul. 2009, To 22 Jul. 2009
          中枢神経系の皮質層形成と神経回路構築の細胞・分子基盤
          集中講義, 名古屋大学, 大学院理学研究科
        • From 01 Apr. 2020, To 30 Sep. 2020
          生物工学特論E
          集中, 大阪大学, 基礎工学部
        • From 09 Jan. 2019, To 09 Jan. 2019
          形態学
          通年, 大阪大学, 医学部
        • From 01 Jun. 2015, To 01 Jun. 2015
          神経科学序説
          通年, 横浜市立 大 学, 生命医科学研究科
        list
          Last Updated :2022/06/24

          Administration

          School management (title, position)

          • From 01 Apr. 2012, To 31 Mar. 2014
            京都大学女性教員懇話会 会計
          • From 01 Apr. 2013, To 31 Mar. 2014
            京都大学女性教員懇話会 代表
          • From 01 Oct. 2014, To 31 Mar. 2016
            京都大学優秀女性研究者賞選考委員会 委員
          • From 01 Oct. 2016, To 31 Mar. 2018
            京都大学優秀女性研究者賞選考委員会 委員
          • From 01 Dec. 2016, To 31 Mar. 2018
            国際教育委員会国際学生交流委員会アムジェン・スカラーズ・プログラム小委員会 委員
          • From 01 Oct. 2019, To 30 Sep. 2020
            男女共同参画推進センター就労支援WG事業推進委員
          • From 01 Oct. 2020, To 30 Sep. 2022
            男女共同参画推進センター就労支援WG事業推進委員
          • From 01 Feb. 2022, To 30 Jun. 2022
            戦略調整会議研究戦略・人材育成検討委員会 委員
          • From 01 Apr. 2022, To 12 May 2022
            研究支援・実験補助対象者選考委員会 委員
          • From 01 Apr. 2022, To 31 Mar. 2024
            設備整備・共用促進委員会 委員
          • From 01 May 2022, To 31 Jul. 2022
            大学ファンド事業計画検討タスクフォース

          Faculty management (title, position)

          • To 31 Mar. 2016
            国際教育委員会
          • From 01 Apr. 2019, To 31 Mar. 2021
            高等研究院物質―細胞統合システム拠点副拠点長

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