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Eiraku, Mototsugu

Institute for Life and Medical Sciences (LiMe) Professor

Eiraku, Mototsugu
list
    Last Updated :2024/06/13

    Basic Information

    Affiliated programs (koza)

    • Graduate School of Engineering, 高分子化学専攻 医用高分子講座, 教授

    Concurrent Affiliation

    • Institute for Advanced Study, ヒト生物学高等研究拠点, 連携研究者
    • Institute for Advanced Study, ヒト生物学高等研究拠点, 主任研究者

    Academic Degree

    • 修士(理学)(京都大学)
    • 博士(理学)(京都大学)

    Research History

    • From Apr. 2022, To Present
      Kyoto University, Institute for Life and Medical Sciences, 教授
    • From Feb. 2017, To Mar. 2022
      Kyoto University, Institute for Frontier Life and Medical Sciences, Professor
    • From Apr. 2015, To Jan. 2017
      RIKEN, Center for Developmental Biology, Team Leader
    • From 2013, To Mar. 2015
      RIKEN, Unit Leader
    • From 2006, To 2013
      RIKEN, 研究員
    • Kyoto University Institute for Frontier Life and Medical Sciences, Professor

    ID,URL

    researchmap URL

    list
      Last Updated :2024/06/13

      Research

      Research Interests

      • 幹細胞
      • 形態形成
      • イメージング
      • 神経発生
      • 試験管内再構築
      • ES細胞
      • 組織形成
      • 細胞間シグナル
      • 顆粒細胞
      • 樹状突起

      Research Areas

      • Life sciences, Developmental biology

      Papers

      • Spatial cell fate manipulation of human pluripotent stem cells by controlling the microenvironment using photocurable hydrogel
        Zhe Wang; Akira Numada; Fumi Wagai; Yusuke Oda; Masatoshi Ohgushi; Koichiro Maki; Taiji Adachi; Mototsugu Eiraku
        Development, 15 Mar. 2024, Peer-reviewed
      • In vitro induction of patterned branchial arch-like aggregate from human pluripotent stem cells
        Yusuke Seto; Ryoma Ogihara; Kaori Takizawa; Mototsugu Eiraku
        Nature Communications, 14 Feb. 2024, Peer-reviewed
      • RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations.
        Masato Ishikawa; Seiichi Sugino; Yoshie Masuda; Yusuke Tarumoto; Yusuke Seto; Nobuko Taniyama; Fumi Wagai; Yuhei Yamauchi; Yasuhiro Kojima; Hisanori Kiryu; Kosuke Yusa; Mototsugu Eiraku; Atsushi Mochizuki
        Communications biology, 28 Dec. 2023, Peer-reviewed
      • How might we build limbs in vitro informed by the modular aspects and tissue-dependency in limb development?
        Rio Tsutsumi; Mototsugu Eiraku
        Frontiers in Cell and Developmental Biology, 22 May 2023, Peer-reviewed
      • Collective nuclear behavior shapes bilateral nuclear symmetry for subsequent left-right asymmetric morphogenesis in Drosophila
        D. Shin; M. Nakamura; Y. Morishita; M. Eiraku; T. Yamakawa; T. Sasamura; M. Akiyama; M. Inaki; K. Matsuno
        Development, 2021, Peer-reviewed
      • Development of intensiometric indicators for visualizing N-cadherin interaction across cells
        Takashi Kanadome; Kanehiro Hayashi; Yusuke Seto; Mototsugu Eiraku; Kazunori Nakajima; Takeharu Nagai; Tomoki Matsuda
        Communications Biology, 07 Oct. 2022, Peer-reviewed
      • Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues
        Guillermo Martínez-Ara; Núria Taberner; Mami Takayama; Elissavet Sandaltzopoulou; Casandra E. Villava; Miquel Bosch-Padrós; Nozomu Takata; Xavier Trepat; Mototsugu Eiraku; Miki Ebisuya
        Nature Communications, 14 Sep. 2022, Peer-reviewed
      • Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model.
        Masatoshi Ohgushi; Nobuko Taniyama; Alexis Vandenbon; Mototsugu Eiraku
        Cell reports, 21 Jun. 2022
      • Pluripotent stem cells in developmental biology (part 2).
        Makoto Ikeya; Yayoi Toyooka; Mototsugu Eiraku
        Development, growth & differentiation, Feb. 2021
      • Pluripotent stem cells in developmental biology.
        Makoto Ikeya; Yayoi Toyooka; Mototsugu Eiraku
        Development, growth & differentiation, Jan. 2021
      • Self-organized formation of developing appendages from murine pluripotent stem cells.
        Mori S; Sakakura E; Tsunekawa Y; Hagiwara M; Suzuki T; Eiraku M
        Nat Commun., Aug. 2019, Peer-reviewed, Invited
      • Toward the formation of neural circuits in human brain organoids.
        Seto Y; Eiraku M
        Curr Opin Cell Biol., Aug. 2019, Peer-reviewed
      • Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration.
        Hung-Ya Tu; Takehito Watanabe; Hiroshi Shirai; Suguru Yamasaki; Masaharu Kinoshita; Keizo Matsushita; Tomoyo Hashiguchi; Hirotaka Onoe; Take Matsuyama; Atsushi Kuwahara; Akiyoshi Kishino; Toru Kimura; Mototsugu Eiraku; Kiyoshi Suzuma; Takashi Kitaoka; Masayo Takahashi; Michiko Mandai
        EBioMedicine, Jan. 2019, Peer-reviewed
      • Human brain development and its in vitro recapitulation.
        Seto Y; Eiraku M
        Neurosci Res., Jan. 2019, Peer-reviewed, Invited
      • Strain-triggered mechanical feedback in self-organizing optic-cup morphogenesis.
        S Okuda; N Takata; Y Hasegawa; M Kawada; Y Inoue; T Adachi; Y Sasai; M Eiraku
        Science advances, Nov. 2018, Peer-reviewed
      • Three-dimensional deformation mode of multicellular epithelial tube under tension and compression tests
        Satoru Okuda; Katsuyuki Unoki; Mototsugu Eiraku; Ken-ichi Tsubota
        Journal of Biomechanical Science and Engineering, Jun. 2018, Peer-reviewed
      • Combining Turing and 3D vertex models reproduces autonomous multicellular morphogenesis with undulation, tubulation, and branching (vol 8, 2386, 2018)
        Satoru Okuda; Takashi Miura; Yasuhiro Inoue; Taiji Adachi; Mototsugu Eiraku
        SCIENTIFIC REPORTS, Jun. 2018, Peer-reviewed
      • Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation.
        Satoshi Iraha; Hung-Ya Tu; Suguru Yamasaki; Takahiro Kagawa; Motohito Goto; Riichi Takahashi; Takehito Watanabe; Sunao Sugita; Shigenobu Yonemura; Genshiro A Sunagawa; Take Matsuyama; Momo Fujii; Atsushi Kuwahara; Akiyoshi Kishino; Naoshi Koide; Mototsugu Eiraku; Hidenobu Tanihara; Masayo Takahashi; Michiko Mandai
        Stem cell reports, 13 Mar. 2018, Peer-reviewed
      • Stem cells and genome editing: approaches to tissue regeneration and regenerative medicine.
        Nozomu Takata; Mototsugu Eiraku
        Journal of human genetics, Feb. 2018, Peer-reviewed
      • Combining Turing and 3D vertex models reproduces autonomous multicellular morphogenesis with undulation, tubulation, and branching
        Satoru Okuda; Takashi Miura; Yasuhiro Inoue; Taiji Adachi; Mototsugu Eiraku
        SCIENTIFIC REPORTS, Feb. 2018, Peer-reviewed
      • Discovery of mechanical feedback mechanism in organogenesis
        Satoru OKUDA; Mototsugu EIRAKU
        The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME, 2018
      • Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism
        Nozomu Takata; Eriko Sakakura; Mototsugu Eiraku; Takeya Kasukawa; Yoshiki Sasai
        NATURE COMMUNICATIONS, Nov. 2017, Peer-reviewed
      • An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation
        Nozomu Takata; Deepti Abbey; Luciano Fiore; Sandra Acosta; Ruopeng Feng; Hyea Jin Gil; Alfonso Lavado; Xin Geng; Ashley Interiano; Geoffrey Neale; Mototsugu Eiraku; Yoshiki Sasai; Guillermo Oliver
        CELL REPORTS, Nov. 2017, Peer-reviewed
      • Role of molecular turnover in dynamic deformation of a three-dimensional cellular membrane
        Satoru Okuda; Mototsugu Eiraku
        BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Oct. 2017, Peer-reviewed
      • A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells
        Masatoshi Ohgushi; Maki Minaguchi; Mototsugu Eiraku; Yoshiki Sasai
        STEM CELL REPORTS, Jul. 2017, Peer-reviewed
      • Contractile actin belt and mesh structures provide the opposite dependence of epithelial stiffness on the spontaneous curvature of constituent cells
        Satoru Okuda; Katsuyuki Unoki; Mototsugu Eiraku; Ken-ichi Tsubota
        DEVELOPMENT GROWTH & DIFFERENTIATION, Jun. 2017, Peer-reviewed
      • Versatile three-dimensional vertex model for analyzing multicellular morphogenesis
        Satoru OKUDA; Mototsugu EIRAKU
        The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME, 2017
      • Telencephalic tissue formation in 3D stem cell culture
        Taisuke Kadoshima; Hideya Sakaguchi; Mototsugu Eiraku
        Organ Regeneration Based on Developmental Biology, 01 Jan. 2017, Peer-reviewed
      • Generation of various telencephalic regions from human embryonic stem cells in three-dimensional culture
        Taisuke Kadoshima; Hideya Sakaguchi; Mototsugu Eiraku
        Methods in Molecular Biology, 2017, Peer-reviewed
      • Generation of a three-dimensional retinal tissue from self-organizing human ESC culture
        Atsushi Kuwahara; Tokushige Nakano; Mototsugu Eiraku
        Methods in Molecular Biology, 2017, Peer-reviewed
      • Emergence of dorsal-ventral polarity in ESC-derived retinal tissue
        Yuiko Hasegawa; Nozomu Takata; Satoru Okuda; Masako Kawada; Mototsugu Eiraku; Yoshiki Sasai
        DEVELOPMENT, Nov. 2016, Peer-reviewed
      • Data describing Rax positive optic-vesicle generation from mouse embryonic stem cells in vitro.
        Nozomu Takata; Mototsugu Eiraku; Eriko Sakakura
        Data in brief, Sep. 2016, Peer-reviewed
      • Modeling cell apoptosis for simulating three-dimensional multicellular morphogenesis based on a reversible network reconnection framework
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Taiji Adachi; Yoshiki Sasai
        BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Aug. 2016, Peer-reviewed
      • Specification of embryonic stem cell-derived tissues into eye fields by Wnt signaling using rostral diencephalic tissue-inducing culture
        Eriko Sakakura; Mototsugu Eiraku; Nozomu Takata
        MECHANISMS OF DEVELOPMENT, Aug. 2016, Peer-reviewed
      • Optimized Culture System to Induce Neurite Outgrowth From Retinal Ganglion Cells in Three-Dimensional Retinal Aggregates Differentiated From Mouse and Human Embryonic Stem Cells
        Yuki Maekawa; Akishi Onishi; Keizo Matsushita; Naoshi Koide; Michiko Mandai; Kiyoshi Suzuma; Takashi Kitaoka; Atsushi Kuwahara; Chikafumi Ozone; Tokushige Nakano; Mototsugu Eiraku; Masayo Takahashi
        CURRENT EYE RESEARCH, 2016, Peer-reviewed
      • Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration
        Hiroshi Shirai; Michiko Mandai; Keizo Matsushita; Atsushi Kuwahara; Shigenobu Yonemura; Tokushige Nakano; Juthaporn Assawachananont; Toru Kimura; Koichi Saito; Hiroko Terasaki; Mototsugu Eiraku; Yoshiki Sasai; Masayo Takahashi
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2016, Peer-reviewed
      • Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
        Chikafumi Ozone; Hidetaka Suga; Mototsugu Eiraku; Taisuke Kadoshima; Shigenobu Yonemura; Nozomu Takata; Yutaka Oiso; Takashi Tsuji; Yoshiki Sasai
        NATURE COMMUNICATIONS, Jan. 2016, Peer-reviewed
      • Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
        Hideya Sakaguchi; Taisuke Kadoshima; Mika Soen; Nobuhiro Narii; Yoshihito Ishida; Masatoshi Ohgushi; Jun Takahashi; Mototsugu Eiraku; Yoshiki Sasai
        NATURE COMMUNICATIONS, Nov. 2015, Peer-reviewed
      • Vertex dynamics simulations of viscosity-dependent deformation during tissue morphogenesis
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Taiji Adachi; Yoshiki Sasai
        BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Apr. 2015, Peer-reviewed
      • Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue
        Atsushi Kuwahara; Chikafumi Ozone; Tokushige Nakano; Koichi Saito; Mototsugu Eiraku; Yoshiki Sasai
        NATURE COMMUNICATIONS, Feb. 2015, Peer-reviewed
      • Mechanical control of notochord morphogenesis by extra-embryonic tissues in mouse embryos
        Yu Imuta; Hiroshi Koyama; Dongbo Shi; Mototsugu Eiraku; Toshihiko Fujimori; Hiroshi Sasaki
        MECHANISMS OF DEVELOPMENT, May 2014, Peer-reviewed
      • Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice
        Juthaporn Assawachananont; Michiko Mandai; Satoshi Okamoto; Chikako Yamada; Mototsugu Eiraku; Shigenobu Yonemura; Yoshiki Sasai; Masayo Takahashi
        STEM CELL REPORTS, May 2014, Peer-reviewed
      • 2P137 3D vertex model for revealing mechanics in multicellular morphogenesis(09. Development & Differentiation,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))
        Okuda Satoru; Eiraku Mototsugu; Sasai Yoshiki
        Seibutsu Butsuri, 2014
      • Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
        Taisuke Kadoshima; Hideya Sakaguchi; Tokushige Nakano; Mika Soen; Satoshi Ando; Mototsugu Eiraku; Yoshiki Sasai
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Dec. 2013, Peer-reviewed
      • Modeling cell proliferation for simulating three-dimensional tissue morphogenesis based on a reversible network reconnection framework
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Oct. 2013, Peer-reviewed
      • Reversible network reconnection model for simulating large deformation in dynamic tissue morphogenesis
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Aug. 2013, Peer-reviewed
      • Apical contractility in growing epithelium supports robust maintenance of smooth curvatures against cell-division-induced mechanical disturbance
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        JOURNAL OF BIOMECHANICS, Jun. 2013, Peer-reviewed
      • Robust Formation and Maintenance of Continuous Stratified Cortical Neuroepithelium by Laminin-Containing Matrix in Mouse ES Cell Culture
        Makoto Nasu; Nozomu Takata; Teruko Danjo; Hideya Sakaguchi; Taisuke Kadoshima; Sugiko Futaki; Kiyotoshi Sekiguchi; Mototsugu Eiraku; Yoshiki Sasai
        PLOS ONE, Dec. 2012, Peer-reviewed
      • In vitro organogenesis in three dimensions: self-organising stem cells
        Yoshiki Sasai; Mototsugu Eiraku; Hidetaka Suga
        DEVELOPMENT, Nov. 2012, Peer-reviewed
      • Self-formation of layered neural structures in three-dimensional culture of ES cells
        Mototsugu Eiraku; Yoshiki Sasai
        CURRENT OPINION IN NEUROBIOLOGY, Oct. 2012, Peer-reviewed
      • Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs
        Tokushige Nakano; Satoshi Ando; Nozomu Takata; Masako Kawada; Keiko Muguruma; Kiyotoshi Sekiguchi; Koichi Saito; Shigenobu Yonemura; Mototsugu Eiraku; Yoshiki Sasai
        CELL STEM CELL, Jun. 2012, Peer-reviewed
      • 1PT219 Simulations of large deformation during tissue morphogenesis using reversible network reconnection model(The 50th Annual Meeting of the Biophysical Society of Japan)
        Okuda Satoru; Inoue Yasuhiro; Eiraku Mototsugu; Sasai Yoshiki; Adachi Taiji
        Seibutsu Butsuri, 2012
      • Relaxation-expansion model for self-driven retinal morphogenesis A hypothesis from the perspective of biosystems dynamics at the multi-cellular level
        Mototsugu Eiraku; Taiji Adachi; Yoshiki Sasai
        BIOESSAYS, Jan. 2012, Peer-reviewed
      • Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissues
        Mototsugu Eiraku; Yoshiki Sasai
        NATURE PROTOCOLS, Jan. 2012, Peer-reviewed
      • Remodeling of Monoplanar Purkinje Cell Dendrites during Cerebellar Circuit Formation
        Megumi Kaneko; Kazuhiko Yamaguchi; Mototsugu Eiraku; Motohiko Sato; Norio Takata; Yoshimoto Kiyohara; Masayoshi Mishina; Hajime Hirase; Tsutomu Hashikawa; Mineko Kengaku
        PLOS ONE, May 2011, Peer-reviewed
      • Self-organizing optic-cup morphogenesis in three-dimensional culture
        Mototsugu Eiraku; Nozomu Takata; Hiroki Ishibashi; Masako Kawada; Eriko Sakakura; Satoru Okuda; Kiyotoshi Sekiguchi; Taiji Adachi; Yoshiki Sasai
        NATURE, Apr. 2011, Peer-reviewed
      • Subregional Specification of Embryonic Stem Cell-Derived Ventral Telencephalic Tissues by Timed and Combinatory Treatment with Extrinsic Signals
        Teruko Danjo; Mototsugu Eiraku; Keiko Muguruma; Kiichi Watanabe; Masako Kawada; Yuchio Yanagawa; John L. R. Rubenstein; Yoshiki Sasai
        JOURNAL OF NEUROSCIENCE, Feb. 2011, Peer-reviewed
      • Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells
        Masatoshi Ohgushi; Michiru Matsumura; Mototsugu Eiraku; Kazuhiro Murakami; Toshihiro Aramaki; Ayaka Nishiyama; Keiko Muguruma; Tokushige Nakano; Hidetaka Suga; Mono Ueno; Toshimasa Ishizaki; Hirofumi Suemori; Shuh Narumiya; Hitoshi Niwa; Yoshiki Sasai
        CELL STEM CELL, Aug. 2010, Peer-reviewed
      • Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
        Mototsugu Eiraku; Kiichi Watanabe; Marni Matsuo-Takasaki; Masako Kawada; Shigenobu Yonemura; Michiru Matsumura; Takafumi Wataya; Ayaka Nishiyama; Keiko Muguruma; Yoshiki Sasail
        CELL STEM CELL, Nov. 2008, Peer-reviewed
      • Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation
        Takafumi Wataya; Satoshi Ando; Keiko Muguruma; Hanako Ikeda; Kiichi Watanabe; Mototsugu Eiraku; Masako Kawada; Jun Takahashi; Nobuo Hashimoto; Yoshiki Sasai
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Aug. 2008, Peer-reviewed
      • Receptor type protein tyrosine phosphatase zeta-pleiotrophin signaling controls endocytic trafficking of DNER that regulates neuritogenesis
        Nobuna Fukazawa; Seisuke Yokoyama; Mototsugu Eiraku; Mineko Kengaku; Nobuaki Maeda
        MOLECULAR AND CELLULAR BIOLOGY, Jul. 2008, Peer-reviewed
      • Impaired cerebellar functions in mutant mice lacking DNER
        A Tohgo; M Eiraku; T Miyazaki; E Miura; S Kawaguchi; M Nishi; M Watanabe; T Hirano; M Kengaku; H Takeshima
        MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2006, Peer-reviewed
      • DNER acts as a neuron-specific Notch ligand during Bergmann glial development
        M Eiraku; A Tohgo; K Ono; M Kaneko; K Fujishima; T Hirano; M Kengaku
        NATURE NEUROSCIENCE, Jul. 2005, Peer-reviewed
      • 小脳ニューロン・グリアの細胞形態形成を制御する細胞間相互作用 (特集 脳の発生分化と回路形成)
        永樂元次; 見学美根子
        神経研究の進歩, Feb. 2005, Invited
      • Dual phases of migration of cerebellar granule cells guided by axonal and dendritic leading processes
        K Kawaji; H Umeshima; M Eiraku; T Hirano; M Kengaku
        MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2004, Peer-reviewed
      • Delta/Notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like ReDeat-cont ining protein T ryeted to dendrites of developing and adult central nervous system neurons
        M Eiraku; Y Hirata; H Takeshima; T Hirano; M Kengaku
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2002, Peer-reviewed

      Misc.

      • 発生過程における時空間制御機構 発生時計依存的な体内時計形成の試験管内再現 細胞時計と中枢時計
        田宮 寛之; 永樂 元次
        日本細胞生物学会大会講演要旨集, Jun. 2020
      • 脳の発生とその異常 A.正常発生 幹細胞からの脳組織形成技術-ES細胞やiPS細胞から脳組織を分化させる技術の現状とその応用について
        田宮寛之; 田宮寛之; 田宮寛之; 永樂元次; 永樂元次
        Clinical Neuroscience, 2020
      • in vitro分化誘導の原理 (特集 iPS細胞/ES細胞の生物学) -- (多能性の発揮)
        永楽 元次
        遺伝 : 生物の科学, Jan. 2014
      • iPS細胞による網膜細胞治療
        高橋 政代; 万代 道子; 杉田 直; 大西 明志; 坂井 徳子; 鎌尾 浩行; 岡本 理志; 小坂田 文隆; 森永 千佳子; 山田 千佳子; 柴田 由美子; 寺田 基剛; 秋丸 裕司; 白井 博志; Assawachananont Juthaporn; 金子 兵; 孫 嘉南; 永楽 元次; 笹井 芳樹; 平見 恭彦; 栗本 康夫; 金村 星余; 西下 直樹; 郷 正博; 川真田 伸; 西田 明弘; 石田 和寛; 宮本 紀子; 広瀬 文隆; 亀田 隆範; 下園 正剛; 藤原 雅史; 大石 明生; 川越 直顕; 大音 壮太郎; 雨宮 かおり; 赤木 忠道; 秋田 穣; 池田 華子; 鈴木 拓也; 春田 雅俊; 秋元 正行; 本田 孔士; 山中 伸弥; 桐生 純一; 寺崎 浩子; Gage Fred H
        日本眼科学会雑誌, Mar. 2016
      • 1D16 Modeling cell apoptosis for simulating three-dimensional multicellular morphogenesis
        OKUDA Satoru; INOUE Yasuhiro; ADACHI Taiji; EIRAKU Mototsugu
        The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME, 2016
      • P7-02 マウス及びヒト胚性幹細胞からの3次元分化培養網膜を用いた網膜神経節細胞からの神経突起伸長(神経の発生・再生,グリア,ポスター発表,組織化学のモーダルシフト,第56回日本組織細胞化学会総会・学術集会)
        前川 有紀; 大西 暁士; 松下 恵三; 小出 直史; 万代 道子; 鈴間 潔; 桑原 篤; 大曽根 親文; 中野 徳重; 永楽 元次; 北岡 隆; 高橋 政代
        日本組織細胞化学会総会プログラムおよび抄録集, 2015
      • 器官をつくる―in vitro眼杯形成モデルと力学シミュレーションによる変形メカニズムの検証
        奥田覚; 永楽元次
        実験医学, 2015
      • Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex (vol 110, pg 20284, 2013)
        Taisuke Kadoshima; Hideya Sakaguchi; Tokushige Nakano; Mika Soen; Satoshi Ando; Mototsugu Eiraku; Yoshiki Sasai
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2014
      • 3D07 In vitro experimental system for observation of cell cycles in optic-cup morphogenesis
        SUZUKI Kensuke; EIRAKU Mototsugu; SUNAGA Junko; SASAI Yoshiki; ADACHI Taiji
        バイオエンジニアリング講演会講演論文集, 08 Jan. 2013
      • Self-formation of optic-cup morphogenesis and retinal tissue elasticity
        N. Takata; E. Sakakura; M. Kawada; M. Eiraku; Y. Sasai
        MOLECULAR BIOLOGY OF THE CELL, 2013
      • 2F16 Modeling Cell Proliferation for Simulating Tissue Morphogenesis Using Reversible Network Reconnection Model
        OKUDA Satoru; INOUE Yasuhiro; Eiraku Mototsugu; SASAI Yoshiki; ADACHI Taiji
        The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME, 2013
      • S021011 Reversible Network Reconnection Simulation of Effects of Apical Contractility on Curvatures of Growing Epithelia
        OKUDA Satoru; INOUE Yasuhiro; EIRAKU Mototsugu; SASAI Yoshiki; ADACHI Taiji
        The Proceedings of Mechanical Engineering Congress, Japan, 2013
      • Self-organization of neural patterns and structures in 3D culture of ES cells
        Y. Sasai; M. Eiraku
        JOURNAL OF NEUROCHEMISTRY, Oct. 2012
      • 8C41 Self-organized formation of optic cup in vitro
        EIRAKU Mototsugu
        バイオエンジニアリング講演会講演論文集, 06 Jan. 2012
      • Large Deformation of Multicellular \nTissue during Morphogenesis Using Reversible Network Reconnection Model
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        Exciting Biologies : Forces in Biology(2012.10.4-6.Dublin, Ireland), 2012, Peer-reviewed
      • Mathematical Model for Large Deformations \nof Multiple-cell Aggregate during Tissue Morphogenesis
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        10th World Congress on Computational Mechanics(WCCM2012)(2012.7.8-13.Sao Paulo, Brazil), 2012, Peer-reviewed
      • Simulations of Large Deformation \nduring Tissue Morphogenesis Using Reversible Network Reconnection Model.
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        日本生物物理学会第50 回年 会(2012.9.22-24.名古屋), 2012, Peer-reviewed
      • Three-dimensional Vertex Model \nfor Morphogenesis of Multiple-cell Tissue with Physical and Topological Consistency.
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        CDB Symposium 2012 : Quantitative Developmental Biology, RIKEN Center for Developmental Biology(2012.3.26-28.Kobe), 2012, Peer-reviewed
      • Three-Dimensional Vertex Model \nfor Simulating Large Deformation of Cell Aggregates during Tissue Morphogenesis
        Satoru Okuda; Yasuhiro Inoue; Mototsugu Eiraku; Yoshiki Sasai; Taiji Adachi
        International Symposium on Cellular Mechanobiology(2012.3.16.Kyoto), 2012, Peer-reviewed
      • 形態形成過程における多細胞組織の大変形シミュレーショ ンのためのリバーシブル・ネットワーク・リコネクションモデル
        奥田覚; 井上康博; 永樂元次; 笹井芳樹; 安達泰治
        日本数理生物学会第22 回大会(2012.9.10 -12.岡山)., 2012, Peer-reviewed
      • 組織発生の形態形成過程における細胞の分裂と成長のモデル化
        奥田覚; 井上康博; 永樂元次; 笹井芳樹; 安達泰治
        日本機械学会第24 回バイオエンジニアリング部門講演会(2012.1.7-8.豊中), 2012, Peer-reviewed
      • Subregional specification of ES cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals
        Teruko Danjo; Mototsugu Eiraku; Keiko Muguruma; Kiichi Watanabe; Masako Kawada; Yuchio Yanagawa; John L. R. Rubenstein; Yoshiki Sasai
        NEUROSCIENCE RESEARCH, 2011
      • Self-organizing optic-cup morphogenesis in three-dimensional culture
        Mototsugu Eiraku; Yoshiki Sasai
        NEUROSCIENCE RESEARCH, 2011
      • J025021 Mathematical Insight into Modeling Morphological Development of Sheet-Like Multicellular Tissue
        OKUDA Satoru; INOUE Yasuhiro; EIRAKU Mototsugu; SASAI Yoshiki; ADACHI Taiji
        The Proceedings of Mechanical Engineering Congress, Japan, 2011
      • シート状多細胞組織の形態発生に関する数理モデルの検討
        奥田 覚; 井上康博; 永樂元次; 笹井芳樹; 安達泰治
        日本機械学会2011 年度年次大会(2011.9.12-15 東京), 2011, Peer-reviewed
      • Self-organized formation of cortical neural tissue from embryonic stem cells
        Mototsugu Eiraku; Yoshiki Sasai
        NEUROSCIENCE RESEARCH, 2009
      • Mechanisms of dendrite arborization of the cerebellar Purkinje cell
        Mineko Kengaku; Megumi Kaneko; Kazuto Fujishima; Mototsugu Eiraku; Tsutomu Hashikawa
        NEUROSCIENCE RESEARCH, 2008
      • Control of neural differentiation from ES cell
        Mototsugu Eiraku; Yoshiki Sasai
        NEUROSCIENCE RESEARCH, 2008
      • Contact-dependent regulation of dendrite and glial fiber arborization mediated by delta/notch-like EGF-related receptor
        M Kengaku; M Eiraku; K Fujishima; T Hirano
        JOURNAL OF NEUROCHEMISTRY, Feb. 2004
      • 小脳か粒細胞の遊走と極性化を制御するPax6の機能
        見学美根子; 山崎崇生; 河路光介; 永楽元次; 平野丈夫; 大隅典子
        生化学, 25 Aug. 2000

      Presentations

      • Manipulation of stem cell differentiation to recapitulate human developmental processes in vitro
        Eiraku Mototsugu
        The 61st Annual Meeting of the Biophysical Society of Japan, 15 Nov. 2023, Invited
      • Neural Development in Stem Cell Culture
        Eiraku Mototsugu
        International Symposium on Neural Development and Diseases, 16 Mar. 2023
      • Neural Development in Stem Cell Culture
        Eiraku Mototsugu
        The 21st Takeda Science Foundation Symposium on Bioscience Towards Understanding Human Development and Evolution, 27 Jan. 2023, Invited
      • 網羅的な遺伝子で集うデータに基づくヒト初期発生の遺伝子制御ネットワークの解明
        永樂元次
        第45回日本分子生物学会年会, 02 Dec. 2022
      • 多能性幹細胞からの機能的組織誘導
        永樂元次
        創立100周年記念 第74回日本生物工学会大会, 18 Oct. 2022, Invited
      • Neural tissue development in stem cell culture
        Mototsugu Eiraku
        ISN-APSN 2022, 01 Sep. 2022, Invited
      • Mechanical forces in morphogenesis
        Mototsugu Eiraku
        24th Biennial Meeting of the International Society for Developmental Neuroscience, 09 May 2022, Invited
      • Neural Development in Stem Cell Culture
        EIRAKU MOTOTSUGU
        The International Symposium Development and Plasticity of Neural Systems, 16 Mar. 2022, Invited
      • Neural Development in Stem Cell Culture
        EIRAKU MOTOTSUGU
        BDR Symposium, 02 Mar. 2022, Invited
      • Challenges in Elucidating Life Phenomena by applying the Engineering-assisted Methods
        EIRAKU MOTOTSUGU
        The 44th Annual Meeting of the Molecular Biology Society of Japan, 03 Dec. 2021, Invited
      • Functional tissue formation from pluripotent stem cells by multicellular autonomy
        EIRAKU MOTOTSUGU
        The 27th East Asia Joint Symposium, 28 Oct. 2021, Invited
      • Self-organized formation of functional tissues from pluripotent stem cells
        永樂元次
        第93回大会「技術が切り拓く多彩な未来 -医療現場への道筋-」, 03 Sep. 2021, Invited
      • 幹細胞からの機能的組織誘導
        永樂 元次
        2021第三回再生学異分野融合研究会, 25 Aug. 2021, Invited
      • 幹細胞からの多細胞組織形成と機能の創発
        永樂元次
        公益財団法人 大隅基礎科学創成財団 2020年度 第6回 創発セミナー 再生の不思議と応用の可能性, 23 Mar. 2021, Invited
      • "Functional 3D tissue formation by in vitro manipulation and cell autonomy"
        Eiraku M
        The 15th International Symposium of The Institute Network for Biomedical Sciences: Cutting Edge of Biomedical and Metabolic Sciences., 06 Nov. 2020, Invited
      • 機能的な脳組織を幹細胞から作る:現時点の到達点と今後の課題
        永樂 元次
        千里ライフサイエンス新適塾 「脳はおもしろい」第27回会合, 07 Jan. 2020, Invited
      • 幹細胞からの自己組織化による神経オルガノイド形成
        永樂 元次
        NEURO2019 Brains Science Takes Flight: Bridging the Mind and Life, 26 Jul. 2019, Invited
      • 神経オルガノイド形成における種特異性の解析
        永樂 元次
        第46回 日本毒性学会学術年会, 27 Jun. 2019, Invited
      • 神経オルガノイド形成における種特異性の解析
        永樂 元次
        第19回日本蛋白質科学会年会 第71回日本細胞生物学会大会合同年次大会, 24 Jun. 2019, Invited
      • Functional 3D tissue formation by in vitro manipulation and multicellular autonomy
        Eiraku M
        State-of-the-Art 3D Tissue Culture & Organoids 2019, 19 Apr. 2019, Invited
      • Self-organization of patterned functional tissues from pluripotent stem cells
        Mototsugu Eiraku
        119th International Titisee Conference:Tissue formation and regeneration: from molecules to models, 30 Mar. 2019, Invited
      • 発生システムの試験管内構築と制御
        永樂 元次
        日本発生生物学会秋季シンポジウム2018, 24 Nov. 2018, Invited
      • Self-organization of patterned tissues from mouse and human stem cells
        Mototsugu Eiraku
        EMBO Workshop :Molecular mechanisms of developmental and regenerative biology, 12 Nov. 2018, Invited
      • 多能性幹細胞からの神経組織形成~海馬組織の再構成はできるか?~
        永樂 元次
        第27回 海馬と高次脳機能学会, 29 Sep. 2018, Invited
      • Functional three-dimensional tissue formation by in vitro manipulation and multicellular autonomy
        Mototsugu Eiraku
        第56回日本生物物理学会年会, 16 Sep. 2018, Invited
      • Self-organized formation of neural organoids from stem cells
        Mototsugu Eiraku
        第40回日本生物学的精神医学会・第61回日本神経化学会大会, 07 Sep. 2018, Invited
      • 多細胞体の自己組織的なパターン形成および形態形成メカニズム
        永樂 元次
        Cell aggregation meeting 2018, 27 Jul. 2018, Invited
      • 多細胞の自己組織化能を利用したin vitro での機能的立体組織の構築
        永樂 元次
        日本機械学会第30回バイオエンジニアリング講演会, 15 Dec. 2017, Invited
      • Self-organization of patterned tissues from mouse and human stem cells
        Mototsugu Eiraku
        Cold Spring Harbor Laboratory Symposium, 08 Dec. 2017, Invited
      • 細胞の自己組織化能を利用したin vitroでの機能的立体組織の構築
        永樂 元次
        第37回比較眼科学会年次大会, 30 Jul. 2017, Invited
      • 多能性幹細胞からの神経組織形成
        永樂 元次
        日本バイオマテリアル学会シンポジウム2016, 21 Nov. 2016, Invited
      • Self-organized formation of patterned tissues from embryonic stem cells
        Mototsugu Eiraku
        Engineering the embryo: beyond Systems Biology, 14 Nov. 2016, Invited
      • Self-organized formation of tissue architectures from pluripotent stem cells
        Mototsugu Eiraku
        Society for Developmental Biology, 75th annual meeting International Society of Differentiation , 19th International Conference, 06 Aug. 2016, Invited
      • 細胞の自己組織化能を利用した in vitro での機能的立体組織の構築
        永樂 元次
        第15回日本再生医療学会総会, 19 Mar. 2016, Invited
      • Generation of complex tissue structure In stem cell culture.
        Mototsugu Eiraku
        CRTD/ISSCR International Symposium, 01 Feb. 2016, Invited
      • Self-organized formation of complex tissues from stem cells
        Mototsugu Eiraku
        BMB2015 (第38回日本分子生物学会年会_第88回日本生化学会大会 合同大会), 04 Dec. 2015, Invited
      • Self-organized formation of complex tissues from stem cells
        Mototsugu Eiraku
        48th Annual Meeting of the Developmental Biologists, 05 Jun. 2015, Invited
      • 細胞の自己組織化を利用したin vitroでの機能的立体組織の構築
        永樂 元次
        第29回日本医学会総会2015関西, 12 Apr. 2015, Invited
      • Self-organized formation of complex tissues from stem cells
        Mototsugu Eiraku
        細胞機能と分子活性の多次元蛍光生体イメージング, 28 Jan. 2015, Invited
      • Tissue intrinsic mechanisms underlying retinal neuroepithelial patterning and morphogenesis
        Mototsugu Eiraku
        第87回日本生化学会大会, 17 Oct. 2014, Invited
      • 多能性幹細胞からの立体神経組織構築手法の確立及びその構築過程の解析
        永樂 元次
        Merk Bioscience Forum 2014, 01 Aug. 2014, Invited
      • 幹細胞からの網膜組織の自己組織化とその応用への課題
        永樂 元次
        第118回日本眼科学会総会, 04 Apr. 2014, Invited

      External funds: Kakenhi

      • Interplay of developmental clock and extracellular environment in brain formation
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        影山 龍一郎
        From 01 Apr. 2021, To 31 Mar. 2022, Project Closed
        発生時計;神経発生;脳構築;神経幹細胞;細胞外環境;大脳構築
      • Understanding the molecular basis that defines species-specific developmental timing
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University;Institute of Physical and Chemical Research
        Mototsugu Eiraku
        From 30 Jun. 2016, To 31 Mar. 2021, Project Closed
        形態形成;多能性幹細胞;種特異的発生様式;神経発生;種特異的発生機構;オルガノイド;種特異的;自己組織化;種特異性;発生;種差;幹細胞;神経;発生時計;1細胞解析;網膜発生;遺伝子発現プロファイル;発生時間スケール;ヒト発生;発生時間;網膜;大脳;ヒトES細胞
      • Interplay of developmental clock and extracellular environment in brain formation
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Institute of Physical and Chemical Research;Kyoto University
        Ryoichiro Kageyama
        From 30 Jun. 2016, To 31 Mar. 2021, Project Closed
        脳構築;発生時計;神経幹細胞;神経発生;数理モデル;分節時計;細胞外環境;大脳構築
      • Establishment of a new methodology for inducing early embryo-like structures from stem cells
        Grant-in-Aid for Scientific Research (B)
        Kyoto University;Institute of Physical and Chemical Research
        Mototsugu Eiraku
        From 01 Apr. 2016, To 31 Mar. 2019, Project Closed
        モルフォゲン;オルガノイド;幹細胞;自己組織化;局所シグナル制御;形態形成;初期発生;肢芽形成;発生制御;局所制御;パターン形成;イメージング;分化制御;器官発生
      • Stress field estimation in three-dimensional optic-cup by image-based modeling
        Grant-in-Aid for Challenging Exploratory Research
        Institute of Physical and Chemical Research
        Satoru Okuda
        From 01 Apr. 2015, To 31 Mar. 2017, Project Closed
        三次元バーテックスモデル;器官形成;バイオメカニクス;3次元バーテックスモデル;バイオメカ二クス
      • 上皮組織の分化パターンと形態形成をつなぐ力学制御メカニズムの解明
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Institute of Physical and Chemical Research
        永樂 元次
        From 01 Apr. 2014, To 31 Mar. 2016, Project Closed
        形態形成;自己組織化;幹細胞;シミュレーション
      • Dorsal and ventral specification in optic cup derived from ES cells in vitro
        Grant-in-Aid for Young Scientists (A)
        The Institute of Physical and Chemical Research
        Mototsugu EIRAKU
        From 01 Apr. 2012, To 31 Mar. 2014, Project Closed
        パターン形成;自己組織化;幹細胞;組織の三次元形態;極性;ES細胞
      • 神経上皮組織の自己組織的な形態形成の基盤となる細胞骨格動態の解明
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        The Institute of Physical and Chemical Research
        永樂 元次
        From 01 Apr. 2012, To 31 Mar. 2014, Project Closed
        立体組織形成;自己組織化;形態形成;幹細胞
      • Analysis of neural tissue development using ES cells culture system
        Grant-in-Aid for Young Scientists (B)
        The Institute of Physical and Chemical Research
        Mototsugu EIRAKU
        From 01 Apr. 2009, To 31 Mar. 2011, Project Closed
        ES細胞;形態形成;器官発生;試験管内再構築;神経発生;イメージング;組織形成;幹細胞
      • 細胞間シグナルによる中枢神経系ニューロン・グリア突起の分岐パターン制御機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        The Institute of Physical and Chemical Research
        見学 美根子
        From 01 Apr. 2005, To 31 Mar. 2006, Project Closed
        DNER;樹状突起;プルキンエ細胞;顆粒細胞;細胞間シグナル
      • 中枢神経系細胞における新型コロナウイルス持続感染機構の解析
        Grant-in-Aid for Scientific Research (C)
        Basic Section 49060:Virology-related
        Kyoto University
        村本 裕紀子
        From 01 Apr. 2022, To 31 Mar. 2025, Granted
        SARS-CoV-2;新型コロナウイルス
      • Development of a new culture system for human coronaviruses using organoids
        Grant-in-Aid for Challenging Research (Exploratory)
        Medium-sized Section 49:Pathology, infection/immunology, and related fields
        Kyoto University
        野田 岳志
        From 30 Jun. 2022, To 31 Mar. 2024, Granted
        オルガノイド;コロナウイルス;インフルエンザウイルス;風邪コロナウイルス
      • より生体に近いオルガノイド創出のための細胞外環境制御技術の開発
        Grant-in-Aid for Transformative Research Areas (A)
        Transformative Research Areas, Section (III)
        Kyoto University
        永樂 元次
        From 01 Apr. 2023, To 31 Mar. 2028, Granted
        幹細胞;オルガノイド;発生生物学;ECM
      • 嗅上皮オルガノイドを用いた嗅受容体遺伝子発現制御機構の解明
        Grant-in-Aid for Scientific Research (B)
        Basic Section 44020:Developmental biology-related
        Kyoto University
        永樂 元次
        From 01 Apr. 2023, To 31 Mar. 2026, Granted
        オルガノイド;嗅上皮
      • 領域研究「細胞外情報を統御するマルチモーダルECM」の統括と運営
        Grant-in-Aid for Transformative Research Areas (A)
        Transformative Research Areas, Section (III)
        Institute of Physical and Chemical Research
        藤原 裕展
        From 01 Apr. 2023, To 31 Mar. 2028, Granted
        細胞外マトリックス;技術支援;研究資源共有化;若手支援;広報
      • 嗅上皮オルガノイドを用いた嗅受容体遺伝子発現制御機構の解明
        Grant-in-Aid for Scientific Research (B)
        Basic Section 44020:Developmental biology-related
        Kyoto University
        永樂 元次
        From 28 Feb. 2024, To 31 Mar. 2026, Adopted
      list
        Last Updated :2024/06/13

        Education

        Teaching subject(s)

        • From 01 Apr. 2024, To 31 Mar. 2025
          Chemical Basis of Life
          7107, Spring, Faculty of Engineering, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Chemical Biology
          7129, Fall, Faculty of Engineering, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Life and Medical Sciences, Adv.
          H665, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2024, To 31 Mar. 2025
          Life and Medical Sciences
          H663, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Chemical Biology
          7129, Fall, Faculty of Engineering, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Chemical Basis of Life
          7107, Spring, Faculty of Engineering, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Frontiers of Biology
          N477, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Life and Medical Sciences, Adv.
          H665, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Life and Medical Sciences
          H663, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Frontiers in the Field of Chemical Biology and Biological Chemistry
          H409, Fall, Graduate School of Engineering, 1.5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Life and Medical Sciences, Adv.
          H665, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Chemical Biology
          7129, Fall, Faculty of Engineering, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Life and Medical Sciences
          H663, Spring, Graduate School of Engineering, 1.5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Frontiers of Biology
          N477, Spring, Institute for Liberal Arts and Sciences, 2
        • From Apr. 2017, To Mar. 2018
          Frontier in Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Course in Multicellular Network
          Spring, 生命科学研究科
        • From Apr. 2018, To Mar. 2019
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          Chemical Biology
          Fall, 工学部
        • From Apr. 2018, To Mar. 2019
          Life and Medical Sciences
          Spring, 工学研究科
        • From Apr. 2018, To Mar. 2019
          Life and Medical Sciences, Adv.
          Spring, 工学研究科
        • From Apr. 2019, To Mar. 2020
          Chemical Biology
          Fall, 工学部
        • From Apr. 2019, To Mar. 2020
          Life and Medical Sciences
          Spring, 工学研究科
        • From Apr. 2019, To Mar. 2020
          Life and Medical Sciences, Adv.
          Spring, 工学研究科
        • From Apr. 2020, To Mar. 2021
          Chemical Biology
          Fall, 工学部
        • From Apr. 2020, To Mar. 2021
          Life and Medical Sciences
          Spring, 工学研究科
        • From Apr. 2020, To Mar. 2021
          Life and Medical Sciences, Adv.
          Spring, 工学研究科
        • From Apr. 2021, To Mar. 2022
          Chemical Biology
          Fall, 工学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Industrial Chemistry
          Spring, 工学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Industrial Chemistry
          Spring, 工学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Industrial Chemistry
          Spring, 工学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Industrial Chemistry
          Spring, 工学部
        • From Apr. 2021, To Mar. 2022
          Life and Medical Sciences
          Spring, 工学研究科
        • From Apr. 2021, To Mar. 2022
          Life and Medical Sciences, Adv.
          Spring, 工学研究科

        Participation in PhD Defense

        • Establishing Cerebral Organoid on a Chip Model for In Vitro Vascularization and Disease Modeling
          Maneesha Shaji, Graduate School of Engineering, Sub-chief Examiner
          23 May 2023

        Part-time lecturer

        • From 29 May 2023, To 29 May 2023
          国立大学法人神戸大学
        • From 23 May 2022, To 23 May 2022
          国立大学法人神戸大学, 医学部
        • From 01 Apr. 2022, To 30 Sep. 2022
          東京大学理学部
        list
          Last Updated :2024/06/13

          Administration

          School management (title, position)

          • From 01 Apr. 2022, To 31 Mar. 2024
            ヒトES細胞研究センター センター長
          • From 01 Apr. 2020, To 31 Mar. 2022
            ヒトES細胞研究センター センター長

          Faculty management (title, position)

          • From 01 Apr. 2023
            医の倫理委員会 委員
          • From 01 Apr. 2022
            (医生物学研究所)予算委員会 委員
          • From 01 Apr. 2022
            ウイルス・幹細胞システム医生物学共同研究拠点専門委員会 委員
          • From 01 Apr. 2022
            ウイルス・幹細胞システム医生物学共同研究拠点運営委員会 委員
          • From 01 Apr. 2022
            ヒトES細胞株樹立・分配事業検討委員会 委員
          • From 01 Jul. 2021
            再生実験動物施設飼育室施設運営委員会 委員
          • From 01 Oct. 2016
            化学物質管理委員会 委員
          • From 01 Apr. 2018
            研究データ保全委員会
          • From 01 Apr. 2021
            施設整備委員会
          • From 01 Oct. 2016, To 31 Mar. 2021
            (旧再生研)予算委員会 委員
          • From 01 Oct. 2016, To 30 Jun. 2021
            再生医科学動物実験専門委員会
          • From 01 Apr. 2018, To 31 Mar. 2022
            再生医学・再生医療の先端融合的共同研究拠点運営委員会
          • From 01 Apr. 2018, To 31 Mar. 2022
            再生医学・再生医療の先端融合的共同研究拠点専門委員会
          • From 06 May 2021, To 31 Mar. 2022
            ウイルス・再生医科学研究所予算委員
          list
            Last Updated :2024/06/13

            Academic, Social Contribution

            Academic Contribution

            • JST創発的研究支援事業岡田パネル アドバイザー
              Other
              JST, From 2023, To Present
            • JSTさきがけ「多細胞」領域アドバイザー
              Other
              JST, From 2019, To Present

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