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Mori, Kazutoshi

Institute for Advanced Study Program-Specific Research Center Professor

Mori, Kazutoshi
list
    Last Updated :2025/05/02

    Basic Information

    Professional Memberships

    • 日本細胞生物学会
    • 日本分子生物学会
    • 日本生化学会
    • The American Society for Cell Biology
    • American Society for Biochemistry and Molecular Biology
    • The Japanese Society for Genome Editing
    • The Biomedical Society for Stress Response

    Academic Degree

    • 薬学修士(京都大学)
    • 薬学博士(京都大学)

    Academic Resume (Graduate Schools)

    • 京都大学, 大学院薬学研究科修士課程製薬化学専攻, 修了

    Academic Resume (Undergraduate School/Majors)

    • 京都大学, 薬学部製薬化学科（転学部）, 卒業

    High School

    • High School

      岡山県立倉敷青陵高校

    Research History

    • Former Institution /Organization Laboratory of Molecular Neurobiology, 助教授
    • From 01 Nov. 2003
      Graduate School of Science, Kyoto University, Peofessor
    • From 01 Apr. 1999
      Graduate School of Biostudies, Kyoto University, Associate Professor
    • From 01 Apr. 1996
      HSP Research Institute, Research Manager
    • From 01 Oct. 1993
      HSP Research Institute, Deputy Research Manager
    • From 01 Apr. 1989
      University of Texas Southwestern Medical Center at Dallas, Postdoctoral Fellow
    • From 01 Apr. 1985
      Gifu Pharmaceutical University, Assistant Professor

    Profile

    • Profile

      working on the biological and physiological importance of the unfolded protein response

    Language of Instruction

    • English

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2025/05/02

      Research

      Research Topics, Overview of the research

      • Research Topics

        Quality Control of Proteins in the Endoplasmic Reticulum

      • Overview of the research

        I am working in the field of protein quality control, focusing on the biological, physiological and evolutional importance of the unfolded protein response (UPR), which is a transcriptional induction program coupled with intracellular signaling from the endoplasmic reticulum (ER) to the nucleus.

      Research Interests

      • Signal Transduction
      • 情報伝達
      • transcriptional regulation
      • protein
      • organelle
      • cell

      Research Areas

      • Life sciences, Pharmacology
      • Life sciences, Pharmaceuticals - health and biochemistry
      • Life sciences, Cell biology
      • Life sciences, Molecular biology

      Papers

      • Tango1L but not Tango1S, Tali and cTAGE5 is required for export of type II collagen in medaka fish.
        Yusuke Yasuda; Tomoka Yoshida; Mahiro Oue; Masaya Sengiku; Tokiro Ishikawa; Shunsuke Saito; Byungseok Jin; Kazutoshi Mori
        Cell structure and function, 23 Jan. 2025
      • 【細胞内タンパク質の社会学 合成・品質管理・輸送・分解のケアシステムと疾患発症機構】危機管理システム 廃棄システム 小胞体ストレス応答によって制御されるDerlins
        小田 裕香子; 森 和俊
        実験医学, Sep. 2005
      • UGGT1/2-mediated reglucosylation ofN-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
        Satoshi Ninagawa; Masaki Matsuo; Deng Ying; Shinya Aso; Kazutoshi Matsushita; Akane Fueki; Shunsuke Saito; Koshi Imami; Yasuhiko Kizuka; Tetsushi Sakuma; Takashi Yamamoto; Hirokazu Yagi; Koichi Kato; Kazutoshi Mori
        19 Oct. 2023
      • 小胞体ストレス応答因子ATF6βの欠損はストレスホルモン依存的な不安症を呈する
        田中 貴士; Nguyen Thi Dinh; Kwankaew Nichakarn; 加藤 伸郎; 森 和俊; 堀 修
        形態・機能, Aug. 2022
      • Proteomic analysis of fatty liver induced by starvation of medaka fish larvae.
        Tomoyo Ikeda; Tokiro Ishikawa; Satoshi Ninagawa; Tetsuya Okada; Masaya Ono; Kazutoshi Mori
        Cell structure and function, 19 Jul. 2023
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      • Detection and Quantification of Calcium Ions in the Endoplasmic Reticulum and Cytoplasm of Cultured Cells Using Fluorescent Reporter Proteins and ImageJ Software
        Shunsuke Saito; Kazutoshi Mori
        BIO-PROTOCOL, 2023
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      • Activation of XBP1 but not ATF6α rescues heart failure induced by persistent ER stress in medaka fish
        Byungseok Jin; Tokiro Ishikawa; Makoto Kashima; Rei Komura; Hiromi Hirata; Tetsuya Okada; Kazutoshi Mori
        Life Science Alliance, 09 May 2023
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      • A motor neuron disease-associated mutation produces non-glycosylated Seipin that induces ER stress and apoptosis by inactivating SERCA2b.
        Shunsuke Saito; Tokiro Ishikawa; Satoshi Ninagawa; Tetsuya Okada; Kazutoshi Mori
        eLife, 29 Nov. 2022
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      • ATF6β Deficiency Elicits Anxiety-like Behavior and Hyperactivity Under Stress Conditions
        Takashi Tanaka; Dinh Thi Nguyen; Nichakarn Kwankaew; Megumi Sumizono; Reika Shinoda; Hiroshi Ishii; Mika Takarada-Iemata; Tsuyoshi Hattori; Seiichi Oyadomari; Nobuo Kato; Kazutoshi Mori; Osamu Hori
        Neurochemical Research, 28 Feb. 2023
      • Loss of ATF6α in a Human Carcinoma Cell Line Is Compensated not by Its Paralogue ATF6β but by Sustained Activation of the IRE1 and PERK Arms for Tumor Growth in Nude Mice
        Shengyu Jin; Byungseok Jin; Tokiro Ishikawa; Satoshi Ninagawa; Tetsuya Okada; Sho Koyasu; Hiroshi Harada; Kazutoshi Mori
        Molecular Biology of the Cell, 25 Jan. 2023
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      • Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis.
        Hieu Minh Ta; Thuong Manh Le; Hiroshi Ishii; Mika Takarada-Iemata; Tsuyoshi Hattori; Koji Hashida; Yasuhiko Yamamoto; Kazutoshi Mori; Ryosuke Takahashi; Yasuko Kitao; Osamu Hori
        Journal of neurochemistry, Dec. 2016, Peer-reviewed
      • The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity.
        Dinh Thi Nguyen; Thuong Manh Le; Tsuyoshi Hattori; Mika Takarada-Iemata; Hiroshi Ishii; Jureepon Roboon; Takashi Tamatani; Takayuki Kannon; Kazuyoshi Hosomichi; Atsushi Tajima; Shusuke Taniuchi; Masato Miyake; Seiichi Oyadomari; Takashi Tanaka; Nobuo Kato; Shunsuke Saito; Kazutoshi Mori; Osamu Hori
        Scientific Reports, Jun. 2021, Peer-reviewed
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      • Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD
        Ginto George; Satoshi Ninagawa; Hirokazu Yagi; Jun-ichi Furukawa; Noritaka Hashii; Akiko Ishii-Watabe; Ying Deng; Kazutoshi Matsushita; Tokiro Ishikawa; Yugoviandi P Mamahit; Yuta Maki; Yasuhiro Kajihara; Koichi Kato; Tetsuya Okada; Kazutoshi Mori
        eLife, 26 Oct. 2021
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      • UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage-specific manner
        Tokiro Ishikawa; Takuya Toyama; Yuki Nakamura; Kentaro Tamada; Hitomi Shimizu; Satoshi Ninagawa; Tetsuya Okada; Yasuhiro Kamei; Tomoko Ishikawa-Fujiwara; Takeshi Todo; Eriko Aoyama; Masaharu Takigawa; Akihiro Harada; Kazutoshi Mori
        JOURNAL OF CELL BIOLOGY, Jun. 2017, Peer-reviewed
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      • Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway
        Satoshi Ninagawa; Tetsuya Okada; Yoshiki Sumitomo; Satoshi Horimoto; Takehiro Sugimoto; Tokiro Ishikawa; Shunichi Takeda; Takashi Yamamoto; Tadashi Suzuki; Yukiko Kamiya; Koichi Kato; Kazutoshi Mori
        JOURNAL OF CELL BIOLOGY, Nov. 2015, Peer-reviewed
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      • EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step
        Satoshi Ninagawa; Tetsuya Okada; Yoshiki Sumitomo; Yukiko Kamiya; Koichi Kato; Satoshi Horimoto; Tokiro Ishikawa; Shunichi Takeda; Tetsushi Sakuma; Takashi Yamamoto; Kazutoshi Mori
        JOURNAL OF CELL BIOLOGY, Aug. 2014, Peer-reviewed
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      • The Unfolded Protein Response Transducer ATF6 Represents a Novel Transmembrane-type Endoplasmic Reticulum-associated Degradation Substrate Requiring Both Mannose Trimming and SEL1L Protein
        Satoshi Horimoto; Satoshi Ninagawa; Tetsuya Okada; Hibiki Koba; Takehiro Sugimoto; Yukiko Kamiya; Koichi Kato; Shunichi Takeda; Kazutoshi Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2013, Peer-reviewed
      • ATF6 alpha/beta-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish
        Tokiro Ishikawa; Tetsuya Okada; Tomoko Ishikawa-Fujiwara; Takeshi Todo; Yasuhiro Kamei; Shuji Shigenobu; Minoru Tanaka; Taro L. Saito; Jun Yoshimura; Shinichi Morishita; Atsushi Toyoda; Yoshiyuki Sakaki; Yoshihito Taniguchi; Shunichi Takeda; Kazutoshi Mori
        MOLECULAR BIOLOGY OF THE CELL, May 2013, Peer-reviewed
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      • Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis
        Lingfang Zeng; Qingzhong Xiao; Mei Chen; Andriana Margariti; Daniel Martin; Aleksandar Ivetic; Heping Xu; Justin Mason; Wen Wang; Gillian Cockerill; Kazutoshi Mori; Julie Yi-Shuan Li; Shu Chien; Yanhua Hu; Qingbo Xu
        Circulation, 23 Apr. 2013, Peer-reviewed
      • The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking perk-mediated translational attenuation
        Riwa Ozasa; Tetsuya Okada; Satomi Nadanaka; Takahiko Nagamine; Alisha Zyryanova; Heather Harding; David Ron; Kazutoshi Mori
        Cell Structure and Function, 2013, Peer-reviewed
      • ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson's Disease
        Koji Hashida; Yasuko Kitao; Hirofumi Sudo; Yoshitaka Awa; Shinichiro Maeda; Kazutoshi Mori; Ryosuke Takahashi; Munekazu Iinuma; Osamu Hori
        PLOS ONE, Oct. 2012, Peer-reviewed
      • Atf6 alpha-null mice are glucose intolerant due to pancreatic beta-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance
        Masahiro Usui; Suguru Yamaguchi; Yasuhiro Tanji; Ryu Tominaga; Yasushi Ishigaki; Manabu Fukumoto; Hideki Katagiri; Kazutoshi Mori; Yoshitomo Oka; Hisamitsu Ishihara
        METABOLISM-CLINICAL AND EXPERIMENTAL, Aug. 2012, Peer-reviewed
      • The specialized unfolded protein response of B lymphocytes: ATF6 alpha-independent development of antibody-secreting B cells
        Ileana V. Aragon; Robert A. Barrington; Suzanne Jackowski; Kazutoshi Mori; Joseph W. Brewer
        MOLECULAR IMMUNOLOGY, Jul. 2012, Peer-reviewed
      • A Thrombospondin-Dependent Pathway for a Protective ER Stress Response
        Jeffrey M. Lynch; Marjorie Maillet; Davy Vanhoutte; Aryn Schloemer; Michelle A. Sargent; N. Scott Blair; Kaari A. Lynch; Tetsuya Okada; Bruce J. Aronow; Hanna Osinska; Ron Prywes; John N. Lorenz; Kazutoshi Mori; Jack Lawler; Jeffrey Robbins; Jeffery D. Molkentin
        CELL, Jun. 2012, Peer-reviewed
      • The Endoplasmic Reticulum Stress Sensor, ATF6 alpha, Protects against Neurotoxin-induced Dopaminergic Neuronal Death
        Naohiro Egawa; Keisuke Yamamoto; Haruhisa Inoue; Rie Hikawa; Katsunori Nishi; Kazutoshi Mori; Ryosuke Takahashi
        JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2011, Peer-reviewed
      • マウス細胞内における28S rRNA 上に生じた紫外線損傷の修復
        宮田淳美; 北畠真; 鈴木健夫; 小林洋平; 坂田知子; 米原伸; 森和俊; 鈴木勉; 大野睦人
        RNA フロンティア ミーティング2011 、大府市,2011 年8 月30 日-9 月1 日, 2011, Peer-reviewed
      • Vertebrate Unfolded Protein Response: Mammalian Signaling Pathways Are Conserved in Medaka Fish
        Tokiro Ishikawa; Yoshihito Taniguchi; Tetsuya Okada; Shunichi Takeda; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2011, Peer-reviewed
      • SEL1L Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Luminal Proteins but not Transmembrane Proteins in Chicken DT40 Cell Line
        Satoshi Ninagawa; Tetsuya Okada; Shunichi Takeda; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2011, Peer-reviewed
      • Luminal Domain of ATF6 Alone Is Sufficient for Sensing Endoplasmic Reticulum Stress and Subsequent Transport to the Golgi Apparatus
        Yoshimi Sato; Satomi Nadanaka; Tetsuya Okada; Katsuya Okawa; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2011, Peer-reviewed
      • Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells
        Shogo Shimasaki; Tomoaki Koga; Tsuyoshi Shuto; Mary Ann Suico; Takashi Sato; Kenji Watanabe; Saori Morino-Koga; Manabu Taura; Seiji Okada; Kazutoshi Mori; Hirofumi Kai
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2010, Peer-reviewed
      • Induction of Liver Steatosis and Lipid Droplet Formation in ATF6 alpha-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress
        Keisuke Yamamoto; Kazuna Takahara; Seiichi Oyadomari; Tetsuya Okada; Takashi Sato; Akihiro Harada; Kazutoshi Mori
        MOLECULAR BIOLOGY OF THE CELL, Sep. 2010, Peer-reviewed
      • Divest Yourself of a Preconceived Idea: Transcription Factor ATF6 Is Not a Soluble Protein!
        Kazutoshi Mori
        MOLECULAR BIOLOGY OF THE CELL, May 2010, Peer-reviewed
      • Signalling Pathways in the Unfolded Protein Response: Development from Yeast to Mammals
        Kazutoshi Mori
        JOURNAL OF BIOCHEMISTRY, Dec. 2009, Peer-reviewed
      • The Sterol-sensing Endoplasmic Reticulum (ER) Membrane Protein TRC8 Hampers ER to Golgi Transport of Sterol Regulatory Element-binding Protein-2 (SREBP-2)/SREBP Cleavage-activated Protein and Reduces SREBP-2 Cleavage
        Masato Irisawa; Jun Inoue; Nozomi Ozawa; Kazutoshi Mori; Ryuichiro Sato
        JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2009, Peer-reviewed
      • Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
        Aya Uemura; Masaya Oku; Kazutoshi Mori; Hiderou Yoshida
        JOURNAL OF CELL SCIENCE, Aug. 2009, Peer-reviewed
      • The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells
        Atsuko Tanimura; Toshiaki Yujiri; Yoshinori Tanaka; Masayuki Hatanaka; Noriyuki Mitani; Yukinori Nakamura; Kazutoshi Mori; Yukio Tanizawa
        LEUKEMIA RESEARCH, Jul. 2009, Peer-reviewed
      • p31 Deficiency Influences Endoplasmic Reticulum Tubular Morphology and Cell Survival
        Takefumi Uemura; Takashi Sato; Takehiro Aoki; Akitsugu Yamamoto; Tetsuya Okada; Rika Hirai; Reiko Harada; Kazutoshi Mori; Mitsuo Tagaya; Akihiro Harada
        MOLECULAR AND CELLULAR BIOLOGY, Apr. 2009, Peer-reviewed
      • pXBP1(U), a Negative Regulator of the Unfolded Protein Response Activator pXBP1(S), Targets ATF6 but not ATF4 in Proteasome-mediated Degradation
        Hiderou Yoshida; Aya Uemura; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2009, Peer-reviewed
      • Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds
        Keisuke Yamamoto; Natsumi Suzuki; Tadashi Wada; Tetsuya Okada; Hiderou Yoshida; Randal J. Kaufman; Kazutoshi Mori
        JOURNAL OF BIOCHEMISTRY, Oct. 2008, Peer-reviewed
      • ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum
        Yusuke Adachi; Keisuke Yamamoto; Tetsuya Okada; Hiderou Yoshida; Akihiro Harada; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2008, Peer-reviewed
      • ATF6 modulates SREBP2-mediated lipogenesis (EMBO Journal (2004) 23, 950-958 DOI:10.1038/sj.emboj.7600106)
        L. Zeng; M. Lu; K. Mori; S. Luo; A.S. Lee; Y. Zhu; J.Y.-J. Shyy
        EMBO Journal, 2008, Peer-reviewed
      • Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation
        Yoshinori Tsukumo; Akihiro Tomida; Osamu Kitahara; Yusuke Nakamura; Shinichi Asada; Kazutoshi Mori; Takashi Tsuruo
        JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2007, Peer-reviewed
      • Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6 alpha and XBP1
        Keisuke Yamamoto; Takashi Sato; Toshie Matsui; Masanori Sato; Tetsuya Okada; Hiderou Yoshida; Akihiro Harada; Kazutoshi Mori
        DEVELOPMENTAL CELL, Sep. 2007, Peer-reviewed
      • Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress
        Satomi Nadanaka; Tetsuya Okada; Hiderou Yoshida; Kazutoshi Mori
        MOLECULAR AND CELLULAR BIOLOGY, Feb. 2007, Peer-reviewed
      • Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
        D. Thomas Rutkowski; Stacey M. Arnold; Corey N. Miller; Jun Wu; Jack Li; Kathryn M. Gunnison; Kazutoshi Mori; Amir A. Sadighi Akha; David Raden; Randal J. Kaufman
        PLOS BIOLOGY, Nov. 2006, Peer-reviewed
      • pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
        H Yoshida; M Oku; M Suzuki; K Mori
        JOURNAL OF CELL BIOLOGY, Feb. 2006, Peer-reviewed
      • Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
        Y Oda; T Okada; H Yoshida; RJ Kaufman; K Nagata; K Mori
        JOURNAL OF CELL BIOLOGY, Jan. 2006, Peer-reviewed
      • XBP1 is critical to protect cells from endoplasmic reticulum stress: Evidence from site-2 protease-deficient Chinese hamster ovary cells
        Hiderou Yoshida; Satomi Nadanaka; Ryuichiro Sato; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2006, Peer-reviewed
      • Analysis of ATF6 activation in site-2 protease-deficient Chinese hamster ovary cells
        Satomi Nadanaka; Hiderou Yoshida; Ryuichiro Sato; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2006, Peer-reviewed
      • Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation
        Satomi Nadanaka; Hiderou Yoshida; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2006, Peer-reviewed
      • Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells
        K Zu; T Bihani; A Lin; YM Park; K Mori; C Ip
        ONCOGENE, Jan. 2006, Peer-reviewed
      • Transformation-associated gene regulation by ATF6 alpha during hepatocarcinogenesis
        M Arai; N Kondoh; N Imazeki; A Hada; K Hatsuse; F Kimura; O Matsubara; K Mori; T Wakatsuki; M Yamamoto
        FEBS LETTERS, Jan. 2006, Peer-reviewed
      • Tumor necrosis factor alpha (TNF alpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNF alpha
        Xue, X; JH Piao; A Nakajima; S Sakon-Komazawa; Y Kojima; K Mori; H Yagita; K Okumura; H Harding; H Nakano
        JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2005, Peer-reviewed
      • Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress
        ZM Huang; T Tan; H Yoshida; K Mori; YJ Ma; TSB Yen
        MOLECULAR AND CELLULAR BIOLOGY, Sep. 2005, Peer-reviewed
      • Deficiency of ATP2C1, a golgi ion pump, induces secretory pathway defects in endoplasmic reticulum ( ER)-associated degradation and sensitivity to ER stress
        J Ramos-Castaneda; YN Park; M Liu; K Hauser; H Rudolph; GE Shull; MF Jonkman; K Mori; S Ikeda; H Ogawa; P Arvan
        JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2005, Peer-reviewed
      • 小胞体ストレス応答によって制御されるDerlins
        小田裕香子; 森和俊
        実験医学「細胞内タンパク質の社会学」 （永田和宏，遠藤斗志也編）Vol. 23, No. 15 : 2345－2351(2005), 2005, Peer-reviewed
      • XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
        R Sriburi; S Jackowski; K Mori; JW Brewer
        JOURNAL OF CELL BIOLOGY, Oct. 2004, Peer-reviewed
      • Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II
        K Yamamoto; H Yoshida; K Kokame; RJ Kaufman; K Mori
        JOURNAL OF BIOCHEMISTRY, Sep. 2004, Peer-reviewed
      • XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
        L Romero-Ramirez; HB Cao; D Nelson; E Hammond; AH Lee; H Yoshida; K Mori; LH Glimcher; NC Denko; AJ Giaccia; QT Le; AC Koong
        CANCER RESEARCH, Sep. 2004, Peer-reviewed
      • A role for the unfolded protein response in optimizing antibody secretion
        KE Gunn; NM Gifford; K Mori; JW Brewer
        MOLECULAR IMMUNOLOGY, Jul. 2004, Peer-reviewed
      • Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum
        S Nadanaka; H Yoshida; F Kano; M Murata; K Mori
        MOLECULAR BIOLOGY OF THE CELL, Jun. 2004, Peer-reviewed
      • A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements
        M Flores-Diaz; JC Higuita; Florin, I; T Okada; P Pollesello; T Bergman; M Thelestam; K Mori; A Alape-Giron
        JOURNAL OF BIOLOGICAL CHEMISTRY, May 2004, Peer-reviewed
      • Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response
        KD Tardif; K Mori; RJ Kaufman; A Siddiqui
        JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2004, Peer-reviewed
      • The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2(+/Akita) pancreatic beta cells
        J Nozaki; H Kubota; H Yoshida; M Naitoh; J Goji; T Yoshinaga; K Mori; A Koizumi; K Nagata
        GENES TO CELLS, Mar. 2004, Peer-reviewed
      • The fusion oncoprotein PML-RAR alpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress
        MM Khan; T Nomura; T Chiba; K Tanaka; H Yoshida; K Mori; S Ishii
        JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2004, Peer-reviewed
      • ATF6 modulates SREBP2-mediated lipogenesis
        LF Zeng; M Lu; K Mori; SZ Luo; AS Lee; Y Zhu; JYJ Shyy
        EMBO JOURNAL, Feb. 2004, Peer-reviewed
      • Autoregulation of the HAC1 gene is required for sustained activation of the yeast unfolded protein response
        N Ogawa; K Mori
        GENES TO CELLS, Feb. 2004, Peer-reviewed
      • Unfolded protein response as a quality control mechanism of proteins
        K. Mori
        Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2004, Peer-reviewed
      • A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6
        T Okada; K Haze; S Nadanaka; H Yoshida; NG Seidah; Y Hirano; R Sato; M Negishi; K Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Aug. 2003, Peer-reviewed
      • Frame switch splicing and regulated intramembrane proteolysis: Key words to understand the unfolded protein response
        K Mori
        TRAFFIC, Aug. 2003, Peer-reviewed
      • Intracellular traffic of membrane-bound transcription factors
        K Mori; S Nadanaka
        SEIKAGAKU, Jun. 2003, Peer-reviewed
      • Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis
        M Shuda; N Kondoh; N Imazeki; K Tanaka; T Okada; K Mori; A Hada; M Arai; T Wakatsuki; O Matsubara; N Yamamoto; M Yamamoto
        JOURNAL OF HEPATOLOGY, May 2003, Peer-reviewed
      • The cargo receptor ERGIC-53 is a target of the unfolded protein response
        B Nyfeler; O Nufer; T Matsui; K Mori; HP Hauri
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2003, Peer-reviewed
      • Dysfunction of the unfolded protein response during global brain ischemia and reperfusion
        R Kumar; GS Krause; H Yoshida; K Mori; DJ DeGracia
        JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Apr. 2003, Peer-reviewed
      • A time-dependent phase shift in the mammalian unfolded protein response
        H Yoshida; T Matsui; N Hosokawa; RJ Kaufman; K Nagata; K Mori
        DEVELOPMENTAL CELL, Feb. 2003, Peer-reviewed
      • Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching
        H Fujita; H Katoh; Y Ishikawa; K Mori; M Negishi
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2002, Peer-reviewed
      • Developmental changes in expression of small GTPase RhoG mRNA in the rat brain
        Y Ishikawa; H Katoh; K Nakamura; K Mori; M Negishi
        MOLECULAR BRAIN RESEARCH, Oct. 2002, Peer-reviewed
      • Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response
        T Okada; H Yoshida; R Akazawa; M Negishi; K Mori
        BIOCHEMICAL JOURNAL, Sep. 2002, Peer-reviewed
      • Gα12 and Gα13 interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
        Yoshiaki Yamaguchi; Hironori Katoh; Kazutoshi Mori; Manabu Negishi
        Current Biology, 06 Aug. 2002, Peer-reviewed
      • Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway
        KD Tardif; K Mori; A Siddiqui
        JOURNAL OF VIROLOGY, Aug. 2002, Peer-reviewed
      • Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2
        H Tanaka; H Fujita; H Katoh; K Mori; M Negishi
        BIOCHEMICAL JOURNAL, Jul. 2002, Peer-reviewed
      • Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers
        H Katoh; A Harada; K Mori; M Negishi
        MOLECULAR AND CELLULAR BIOLOGY, May 2002, Peer-reviewed
      • Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
        T Gotoh; S Oyadomari; K Mori; M Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2002, Peer-reviewed
      • IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
        K Lee; W Tirasophon; XH Shen; M Michalak; R Prywes; T Okada; H Yoshida; K Mori; RJ Kaufman
        GENES & DEVELOPMENT, Feb. 2002, Peer-reviewed
      • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
        H Yoshida; T Matsui; A Yamamoto; T Okada; K Mori
        CELL, Dec. 2001, Peer-reviewed
      • Complementary signaling pathways regulate the unfolded protein response and are required for C-elegans development
        XH Shen; RE Ellis; K Lee; CY Liu; K Yang; A Solomon; H Yoshida; R Morimoto; DM Kurnit; K Mori; RJ Kaufman
        CELL, Dec. 2001, Peer-reviewed
      • Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations
        T Katayama; K Imaizumi; A Honda; T Yoneda; T Kudo; M Takeda; K Mori; R Rozmahel; P Fraser; P St George-Hyslop; M Tohyama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2001, Peer-reviewed
      • RhoA Inhibits the Nerve Growth Factor-induced Rac1 Activation through Rho-associated Kinase-dependent Pathway
        Y. Yamaguchi; H. Katoh; H. Yasui; K. Mori; M. Negishi
        Journal of Biological Chemistry, 01 Jun. 2001, Peer-reviewed
      • Differential responses to nerve growth factor and epidermal growth factor in neurite outgrowth of PC12 cells are determined by Rac1 activation systems
        H Yasui; H Katoh; Y Yamaguchi; J Aoki; H Fujita; K Mori; M Negishi
        JOURNAL OF BIOLOGICAL CHEMISTRY, May 2001, Peer-reviewed
      • Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response
        K Haze; T Okada; H Yoshida; H Yanagi; T Yura; M Negishi; K Mori
        BIOCHEMICAL JOURNAL, Apr. 2001, Peer-reviewed
      • Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6 alpha and 6 beta that activates the mammalian unfolded protein response
        H Yoshida; T Okada; K Haze; H Yanagi; T Yura; M Negishi; K Mori
        MOLECULAR AND CELLULAR BIOLOGY, Feb. 2001, Peer-reviewed
      • Rnd1, a novel Rho family GTPase, induces the formation of neuritic processes in PC12 cells
        J Aoki; H Katoh; K Mori; M Negishi
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2000, Peer-reviewed
      • Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells
        H Katoh; H Yasui; Y Yamaguchi; J Aoki; H Fujita; K Mori; M Negishi
        MOLECULAR AND CELLULAR BIOLOGY, Oct. 2000, Peer-reviewed
      • Receptor isoform-specific interaction of prostaglandin EP3 receptor with muskelin
        H Hasegawa; H Katoh; H Fujita; K Mori; M Negishi
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Sep. 2000, Peer-reviewed
      • ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
        H Yoshida; T Okada; K Haze; H Yanagi; T Yura; M Negishi; K Mori
        MOLECULAR AND CELLULAR BIOLOGY, Sep. 2000, Peer-reviewed
      • Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast
        YD Sun; R Taniguchi; D Tanoue; T Yamaji; H Takematsu; K Mori; T Fujita; T Kawasaki; Y Kozutsumi
        MOLECULAR AND CELLULAR BIOLOGY, Jun. 2000, Peer-reviewed
      • Tripartite management of unfolded proteins in the endoplasmic reticulum
        K Mori
        CELL, May 2000, Peer-reviewed
      • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
        K Haze; H Yoshida; H Yanagi; T Yura; K Mori
        MOLECULAR BIOLOGY OF THE CELL, Nov. 1999, Peer-reviewed
      • Cellular response to endoplasmic reticulum stress mediated by unfolded protein response pathway
        K. Mori
        Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1999, Peer-reviewed
      • Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins - Involvement of basic leucine zipper transcription factors
        H Yoshida; K Haze; H Yanagi; T Yura; K Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 1998, Peer-reviewed
      • Palindrome with spacer of one nucleotide is characteristic of the cis-acting unfolded protein response element in Saccharomyces cerevisiae
        K Mori; N Ogawa; T Kawahara; H Yanagi; T Yura
        JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 1998, Peer-reviewed
      • Unconventional splicing of HAC1/ERN4 mRNA required for the unfolded protein response - Sequence-specific and non-sequential cleavage of the splice sites
        T Kawahara; H Yanagi; T Yura; K Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 1998, Peer-reviewed
      • Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response
        T Kawahara; H Yanagi; T Yura; K Mori
        MOLECULAR BIOLOGY OF THE CELL, Oct. 1997, Peer-reviewed
      • Signalling from endoplasmic reticulum to nucleus: Transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway
        K Mori; T Kawahara; H Yoshida; H Yanagi; T Yura
        GENES TO CELLS, Sep. 1996, Peer-reviewed
      • ISOLATION AND CHARACTERIZATION OF ENDOGENOUS LIGANDS FOR LIVER MANNAN-BINDING PROTEIN
        K MORI; T KAWASAKI; YAMASHINA, I
        ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Aug. 1988, Peer-reviewed
      • SUBCELLULAR-DISTRIBUTION OF THE MANNAN-BINDING PROTEIN AND ITS ENDOGENOUS INHIBITORS IN RAT-LIVER
        K MORI; T KAWASAKI; YAMASHINA, I
        ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1984, Peer-reviewed
      • IDENTIFICATION OF THE MANNAN-BINDING PROTEIN FROM RAT LIVERS AS A HEPATOCYTE PROTEIN DISTINCT FROM THE MANNAN RECEPTOR ON SINUSOIDAL CELLS
        K MORI; T KAWASAKI; YAMASHINA, I
        ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, Peer-reviewed
      • Endoplasmic reticulum-associated degradation controls virus protein homeostasis that is required for the flavivirus propagation
        Keisuke Tabata; Masashi Arakawa; Kotaro Ishida; Makiko Kobayashi; Atsuki Nara; Takehiro Sugimoto; Tetsuya Okada; Kazutoshi Mori; Eiji Morita
        Journal of Virology, 12 May 2021
      • Mechanisms of productive folding and endoplasmic reticulum-associated degradation of glycoproteins and non-glycoproteins.
        Satoshi Ninagawa; Ginto George; Kazutoshi Mori
        Biochimica et biophysica acta. General subjects, 11 Dec. 2020
      • Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes.
        Satoshi Ninagawa; Seiichiro Tada; Masaki Okumura; Kenta Inoguchi; Misaki Kinoshita; Shingo Kanemura; Koshi Imami; Hajime Umezawa; Tokiro Ishikawa; Robert B Mackin; Seiji Torii; Yasushi Ishihama; Kenji Inaba; Takayuki Anazawa; Takahiko Nagamine; Kazutoshi Mori
        eLife, 17 Nov. 2020
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      • 抗精神病薬オランザピンによって,プロインスリンは分子間ジスルフィド結合を介した構造異常が誘発され,小胞体関連分解によって処理される
        蜷川 暁; 多田 誠一郎; 奥村 正樹; 井ノ口 健太; 木下 岬; 金村 進吾; 今見 考志; 梅沢 元; 石川 時郎; 岡田 徹也; Mackin Robert; 鳥居 征司; 石濱 泰; 稲葉 謙次; 穴澤 貴行; 長嶺 敬彦; 森 和俊
        日本細胞生物学会大会講演要旨集, Jun. 2020
      • 第二世代抗精神病薬オランザピンは、ジスルフィド結合の形成異常を起因としたプロインスリンの小胞体関連分解を誘発する
        蜷川 暁; 多田 誠一郎; 井ノ口 健太; 今見 考志; 梅澤 元; 石川 時郎; 岡田 徹也; Robert Mackin; 鳥居 征司; 石濱 泰; 穴澤 貴行; 長嶺 敬彦; 森 和俊
        日本薬学会年会要旨集, Mar. 2020
      • EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.
        Ginto George; Satoshi Ninagawa; Hirokazu Yagi; Taiki Saito; Tokiro Ishikawa; Tetsushi Sakuma; Takashi Yamamoto; Koshi Imami; Yasushi Ishihama; Koichi Kato; Tetsuya Okada; Kazutoshi Mori
        eLife, 17 Feb. 2020, Peer-reviewed
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      • Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish.
        Byungseok Jin; Tokiro Ishikawa; Mai Taniguchi; Satoshi Ninagawa; Tetsuya Okada; Shigehide Kagaya; Kazutoshi Mori
        Cell structure and function, 07 Feb. 2020
      • Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF6.
        Hibiki Koba; Shengyu Jin; Nanami Imada; Tokiro Ishikawa; Satoshi Ninagawa; Tetsuya Okada; Tetsushi Sakuma; Takashi Yamamoto; Kazutoshi Mori
        Cell structure and function, 30 Jan. 2020
      • メダカを用いた小胞体ストレスに起因するアポトーシス分子機構の解析
        陳 炳碩; 石川 時郎; 蜷川 暁; 岡田 徹也; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2019
      • 小胞体ストレスセンサーATF6αはジスルフィド結合を介して2種類の二量体を形成する(Endoplasmic reticulum stress sensor ATF6α forms two types of dimers via disulfide-bonding)
        古場 玲; 金 聖宇; 岡田 徹也; 石川 時郎; 蜷川 暁; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2019
      • 小胞体膜タンパク質Seipinの神経変性誘導変異体に起因する小胞体ストレス発生機構の解析
        齊藤 峻介; 石川 時郎; 蜷川 暁; 岡田 徹也; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2019
      • タンパク質の運命を制御する生体システムと疾病のフロンティア 第二世代抗精神病薬オランザピンは、副作用としてProinsulinの適切なジスルフィド結合形成を阻害し糖尿病を誘発する
        蜷川 暁; 岡田 徹也; 梅澤 元; 石川 時郎; 鳥居 征司; Mackin Robert; 今見 考志; 石濱 泰; 長嶺 敬彦; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2019, Peer-reviewed
      • 第二世代抗精神病薬オランザピンがインスリン分泌不全を引き起こし、糖尿病を誘起する分子メカニズムの解析
        蜷川 暁; 岡田 徹也; 今見 考志; 梅澤 元; 石川 時郎; 鳥居 征司; Mackin Robert; 石濱 泰; 長嶺 敬彦; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2018, Peer-reviewed
      • A collection of transgenic medaka strains for efficient site-directed transgenesis mediated by phiC31 integrase.
        Tokiro Ishikawa; Satoshi Ansai; Masato Kinoshita; Kazutoshi Mori
        G3: Genes, Genomes, Genetics, Aug. 2018, Peer-reviewed
      • The exercise-inducible bile acid receptor Tgr5 improves skeletal muscle function in mice.
        Sasaki T; Kuboyama A; Mita M; Murata S; Shimizu M; Inoue J; Mori K; Sato R
        The Journal of biological chemistry, Jun. 2018, Peer-reviewed
      • 第二世代抗精神病薬オランザピンが、副作用として糖尿病を引き起こす分子メカニズムの解析 インスリンは、適切なジスルフィド結合形成を阻害され、小胞体関連分解により処理される
        蜷川 暁; 岡田 徹也; 梅澤 元; 石川 時郎; 鳥居 征司; Mackin Robert; 長嶺 敬彦; 森 和俊
        生命科学系学会合同年次大会, Dec. 2017
      • Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish
        Ishikawa T; Kashima M; Nagano A J; Ishikawa-Fujiwara T; Kamei Y; Todo T; Mori K
        eLife, Oct. 2017, Peer-reviewed
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      • SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation
        Takehiro Sugimoto; Satoshi Ninagawa; Shimpei Yamano; Tokiro Ishikawa; Tetsuya Okada; Shunichi Takeda; Kazutoshi Mori
        CELL STRUCTURE AND FUNCTION, 2017, Peer-reviewed
      • A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models
        Natalia J. Martinez; Ganesha Rai; Adam Yasgar; Wendy A. Lea; Hongmao Sun; Yuhong Wang; Diane K. Luci; Shyh-Ming Yang; Kana Nishihara; Shunichi Takeda; Mohiuddin Sagor; Irina Earnshaw; Tetsuya Okada; Kazutoshi Mori; Kelli Wilson; Gregory J. Riggins; Menghang Xia; Maurizio Grimaldi; Ajit Jadhav; David J. Maloney; Anton Simeonov
        PLOS ONE, Aug. 2016, Peer-reviewed
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      • オルガネラ局域の間取り図 分解執行局域における新展開
        蜷川 暁; 岡田 徹也; 住友 嘉樹; 堀本 賢; 鈴木 匡; 武田 俊一; 佐久間 哲史; 山本 卓; 神谷 由紀子; 加藤 晃一; 森 和俊
        日本細胞生物学会大会講演要旨集, May 2016
      • Mannose trimming mechanism in endoplasmic reticulum-associated degradation of glycoproteins
        Tetsuya Okada; Satoshi Ninagawa; Kazutoshi Mori
        Seikagaku, 2016, Peer-reviewed
      • Deletion of Atf6 alpha enhances kainate-induced neuronal death in mice
        Dai Kezuka; Mika Tkarada-Iemata; Tsuyoshi Hattori; Kazutoshi Mori; Ryosuke Takahashi; Yasuko Kitao; Osamu Hori
        NEUROCHEMISTRY INTERNATIONAL, Jan. 2016, Peer-reviewed
      • 糖鎖非依存小胞体関連分解経路によるシビアな構造異常糖タンパク質の強制分解
        蜷川 暁; 岡田 徹也; 住友 嘉樹; 堀本 賢; 杉本 岳大; 石川 時郎; 武田 俊一; 山本 卓; 神谷 由紀子; 加藤 晃一; 森 和俊
        日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015
      • Derlin2/3およびHerp1/2はSEL1L依存的な構造異常タンパク質分解経路に必要である
        杉本 岳大; 蜷川 暁; 山野 晋平; 石川 時郎; 岡田 徹也; 武田 俊一; 森 和俊
        日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015
      • Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.
        Koga T; Suico MA; Shimasaki S; Watanabe E; Kai Y; Koyama K; Omachi K; Morino-Koga S; Sato T; Shuto T; Mori K; Hino S; Nakao M; Kai H
        The Journal of biological chemistry, Dec. 2015, Peer-reviewed
      • Deletion of Atf6 alpha impairs astroglial activation and enhances neuronal death following brain ischemia in mice
        Akifumi Yoshikawa; Tomoya Kamide; Koji Hashida; Hieu Minh Ta; Yuki Inahata; Mika Takarada-Iemata; Tsuyoshi Hattori; Kazutoshi Mori; Ryosuke Takahashi; Tomohiro Matsuyama; Yutaka Hayashi; Yasuko Kitao; Osamu Hori
        JOURNAL OF NEUROCHEMISTRY, Feb. 2015, Peer-reviewed
      • ERにおける蛋白質品質管理システムに関する逆遺伝学的解析(Reverse Genetic Analysis of Protein Quality Control System in the ER)
        蜷川 暁; 住友 嘉樹; 岡田 徹也; 武田 俊一; 森 和俊
        日本生化学会大会プログラム・講演要旨集, Sep. 2011
      • トリDT40細胞のERADの解析 Sel1Lノックアウトの影響(Analysis of ERAD in chicken DT40 cells: effects of Sel1L knockout)
        蜷川 暁; 岡田 徹也; 武田 俊一; 森 和俊
        日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010

      Misc.

      • Folding or Degradation, Molecular Mechanisms Determining the Fate of Glycoproteins in the Endoplasmic Reticulum
        蜷川暁; 蜷川暁; 松尾將生; DENG Ying; 森和俊
        日本分子生物学会年会プログラム・要旨集(Web), 2023
      • 小胞体における構造不全糖タンパク質の代謝タイミング決定の分子機構
        蜷川暁; 森和俊
        日本生化学会大会(Web), 2023
      • Elucidating mechanisms underlying the robustness of the newly synthesized protein load in the endoplasmic reticulum
        蜷川暁; 蜷川暁; 森和俊
        日本分子生物学会年会プログラム・要旨集(Web), 2022
      • タンパク質個性の基盤構造形成の場としての視座からの小胞体の機能解明
        蜷川暁; 蜷川暁; 森和俊
        日本生化学会大会(Web), 2022
      • UGGTs prevent premature degradation of unstable and misfolded glycoproteins in the endoplasmic reticulum
        蜷川暁; 蜷川暁; 松尾將生; DENG Ying; 阿曽伸哉; 松下和俊; 笛木茜; 斎藤俊介; 今見考志; 木塚康彦; 佐久間哲史; 山本卓; 矢木宏和; 加藤晃一; 加藤晃一; 加藤晃一; 森和俊
        日本糖質学会年会要旨集, 2023
      • UGGTs affect not only glycoprotein folding but also degradation
        松尾將生; DENG Ying; 矢木宏和; 矢木宏和; 津曲和哉; 笛木茜; 今見考志; 加藤晃一; 加藤晃一; 加藤晃一; 森和俊; 蜷川暁; 蜷川暁
        日本分子生物学会年会プログラム・要旨集(Web), 2023
      • 小胞体膜結合性転写因子ATF6を小胞体ストレス依存的に還元する仕組みの解析
        佐藤吉美; 灘中里美; 岡田徹也; 森和俊
        生化学, 2009
      • 膜結合性転写因子ATF6を小胞体ストレス依存的に還元する仕組みの解析
        佐藤吉美; 灘中里美; 岡田徹也; 森和俊
        生化学, 2007
      • 小胞体ストレス応答に関与する膜結合性転写因子ATF6の内腔領域に位置するシステイン残基の還元がsite-1 proteaseによるATF6の効率的な切断に必要である
        灘中里美; 吉田秀郎; 安達雄亮; 森和俊
        日本分子生物学会年会プログラム・講演要旨集, 2004
      • セリンプロテアーゼインヒビターAEBSFは小胞体膜結合性転写因子ATF6の活性化を抑制する
        岡田徹也; 岡田徹也; 土師京介; 灘中里美; 灘中里美; 吉田秀郎; 吉田秀郎; 平野祐子; 佐藤隆一郎; 根岸学; 森和俊; 森和俊
        日本細胞生物学会大会講演要旨集, 2003
      • 小胞体におけるタンパク質の品質管理機構
        森和俊; 岡田徹也; 山本晃; 灘中里美; 吉田秀郎
        日本細胞生物学会大会講演要旨集, 2001
      • Molecular cloning and characterization of a major component of the unfolded protein-response transcription factor.
        K Mori; T Kawahara; H Yoshida; H Yanagi; T Yura
        MOLECULAR BIOLOGY OF THE CELL, Dec. 1996
      • 小胞体からはじまる多彩なシグナルと包括的生命機能制御 網膜神経細胞死における小胞体ストレス応答の役割
        宝田 美佳; 郡山 恵樹; 森 和俊; 堀 修
        生命科学系学会合同年次大会, Dec. 2017
      • Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors (vol 273, pg 33741, 1998)
        H Yoshida; K Haze; H Yanagi; T Yura; K Mori
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 1999
      • Cooperation of IRE1 alpha, ATF6, and XBP1 in the unfolded protein response in the endoplasmic reticulum (ER)
        KH Lee; W Tirasophon; T Okada; H Yoshida; K Mori; RJ Kaufman
        FASEB JOURNAL, Mar. 2002
      • 高等動物におけるN型糖鎖トリミングを基軸とした小胞体関連分解機構の解析
        蜷川暁; GEORGE Ginto; 矢木宏和; 住友嘉樹; 神谷由紀子; 石川時郎; 武田俊一; 佐久間哲史; 山本卓; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本糖質学会年会要旨集, 2019
      • BiPの誘導機構--小胞体から核への情報伝達 (分子シャペロンとその誘導<特集>)
        森 和俊
        蛋白質核酸酵素, Apr. 1994
      • unfolded protein responseを制御する遺伝子群
        吉田 秀郎; 森 和俊
        遺伝子医学, 2002
      • Mechanism of signaling from endoplasmic reticulum to cell nucleus
        MORI Kazutoshi; OGAWA Naoki; KAWAHARA Tetsushi; YANAGI Hideki; YURA Takashi
        日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998
      • cis-acting element and transcription factors responsible for transcriptional induction of mammalian ER chaperones
        YOSHIDA H.; HAZE K.; MORI K.; YANAGI H.; YURA T.
        日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998
      • Analysis of transcription factor ATF6 involved in ER stress response
        HAZE K.; YOSHIDA H.; MORI K.; YANAGI H.; YURA T.
        日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998
      • Cell protection and death induction of ATF6 alpha, in ER stress response induced by Pael-R
        Naohiro Egawa; Keisuke Yamamoto; Haruhisa Inoue; Kengo Uemura; Satoshi Ogawa; Kazutoshi Mori; Ryosuke Takahashi
        NEUROSCIENCE RESEARCH, 2008
      • The second-generation antipsychotic olanzapine induces aberrant intermolecular disulfide bonds of proinsulin
        蜷川暁; 多田誠一郎; 奥村正樹; 井ノ口健太; 木下岬; 金村進吾; 金村進吾; 今見考志; 梅澤元; 石川時郎; MACKIN Robert; 鳥居征司; 石濱泰; 稲葉謙次; 穴澤貴行; 長嶺敬彦; 森和俊
        日本細胞生物学会大会(Web), 2021
      • The second generation antipsychotic olanzapine induces atypical development of diabetes due to aberrant disulfide bond formations of proinsulin in pancreatic beta cells
        蜷川暁; 多田誠一郎; 奥村正樹; 井ノ口健太; 木下岬; 金村進吾; 今見考志; 梅澤元; 石川時郎; MACKIN Robert; 鳥居征司; 石濱泰; 稲葉謙次; 穴澤貴行; 長嶺敬彦; 森和俊
        日本薬学会年会要旨集(Web), 2021
      • The regulation by OS9 and XTP3B in ER-associated degradation depends on the degree of structural abnormality of degradation substrates
        松下和智; 蜷川暁; 杉本岳大; 岡田徹也; 石川時郎; 佐久間哲史; 山本卓; 森和俊
        日本糖質学会年会要旨集, 2021
      • A mannosidase in the endoplasmic reticulum exerts its function by protein-protein association
        蜷川暁; GEORGE Ginto; 矢木宏和; 古川潤一; 橋井則貴; 石井明子; DENG Ying; 石川時郎; 今見考志; 石濱泰; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本分子生物学会年会プログラム・要旨集(Web), 2021
      • Elucidation of molecular mechanisms and functions of N-glycan mannose trimming required for glycoprotein ER-associated degradation pathway
        蜷川暁; GEORGE Ginto; 矢木宏和; 住友嘉樹; 真木勇太; 石川時郎; 佐久間哲史; 山本卓; 今見考志; 石濱泰; 梶原康宏; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本糖質学会年会要旨集, 2021
      • 酵母小胞体内腔のストレスタンパク質とその誘導
        森 和俊
        生化学, Dec. 1994
      • An IFN-gamma-stimulated ATF6-C/EBP-beta-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy
        Padmaja Gade; Girish Ramachandran; Uday B. Maachani; Mark A. Rizzo; Tetsuya Okada; Ron Prywes; Alan S. Cross; Kazutoshi Mori; Dhananjaya V. Kalvakolanu
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jun. 2012, Peer-reviewed
      • Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow
        Lingfang Zeng; Anna Zampetaki; Andriana Margariti; Anna Elena Pepe; Saydul Alam; Daniel Martin; Qingzhong Xiao; Wen Wang; Zheng-Gen Jin; Gillian Cockerill; Kazutoshi Mori; Yi-shuan Julie Li; Yanhua Hu; Shu Chien; Qingbo Xu
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2009, Peer-reviewed
      • Darlin-2 and Darlin-3 regulated by mammalian Unfolded Protein Response are required for ER-associated Degradation.
        Yukako Oda; Tetsuya Okada; Hiderou Yoshida; Randal J. kaufman; Kazuhiro Nagata; Kazutoshi Mori
        International Symposium on Life of Proteins, Awaji （Japan）, 2005. 10. 30－11.3, 30 Oct. 2005, Peer-reviewed
      • CERD, a novel \ncomponent of ER-associated degradation machinery, regulated by the IRE1－XBP1 pathway.
        Tetsuya Okada; Yukako Oda; Hiderou Yoshida; Randal J. Kaufman; Kazuhiro Nagata; Kazutoshi Mori
        FASEB 2004 Summer Reserch Conferences（2004.9.31～8.5. Vermont （USA）, 2004, Peer-reviewed
      • IRE1－XBP1 経路で制御される新規遺伝子CERD1/Derlin－2 の機能解析
        小田裕香子; 岡田徹也; 吉田秀郎; Randal J. Kaufman; 永田和宏; 森和俊
        第27 回日本分子生物学会大会（2004.12.9. 神戸市）, 2004, Peer-reviewed
      • MRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response
        K Mori; N Ogawa; T Kawahara; H Yanagi; T Yura
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2000, Peer-reviewed
      • 小胞体関連分解因子EDEM2は,TXNDC11とジスルフィド結合を介した複合体を形成し,マンノシダーゼ活性を発揮する
        蜷川暁; GEORGE Ginto; 矢木宏和; 住友嘉樹; 石川時郎; 佐久間哲史; 山本卓; 今見考志; 石濱泰; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本生化学会大会(Web), 2020
      • An enzymatic activity of EDEM2 is endowed by TXNDC11 connected via a disulfide bond
        蜷川暁; GEORGE Ginto; 矢木宏和; 斎藤泰輝; 住友嘉樹; 石川時郎; 佐久間哲史; 山本卓; 今見考志; 石濱泰; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本糖質学会年会要旨集, 2020
      • 小胞体タンパク質品質管理機構の中心を担うN型糖鎖依存/非依存小胞体関連分解経路の分子メカニズムの解析
        蜷川暁; GINTO George; 矢木宏和; 今見考志; 石濱泰; 石川時郎; 佐久間哲史; 山本卓; 武田俊一; 加藤晃一; 加藤晃一; 岡田徹也; 森和俊
        日本分子生物学会年会プログラム・要旨集(Web), 2019
      • SIRT1 IS UP-REGULATED BY ER STRESS VIA THE PI3K-AKT-GSK3 beta PATHWAY AND MEDIATES ER STRESS-INDUCED HEPATOCELLULAR INJURY
        Koga Tomoaki; Suico Mary-Ann; Shimasaki Shogo; Watanabe Eriko; Kai Yukari; Koyama Kosuke; Omachi Kohei; Morino-Koga Saori; Sato Takashi; Shuto Tsuyoshi; Mori Kazutoshi; Hino Shinjiro; Nakao Mitsuyoshi; Kai Hirofumi
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2016, Peer-reviewed
      • 糖鎖依存的構造異常タンパク質分解に必須な糖鎖刈り込み機構を解明 〜革新的ゲノム編集技術によって従来のモデルを一新〜 NMR
        蜷川 暁; 加藤晃一; 森 和俊
        化学と生物, 2015
      • EDEM1/2/3 are alpha 1,2-mannosidases essential for endoplasmic reticulum-associated degradation of glycoproteins
        Satoshi Ninagawa; Tetsuya Okada; Yoshiki Sumitomo; Yukiko Kamiya; Satoshi Horimoto; Tokiro Ishikawa; Shunichi Takeda; Tetsushi Sakuma; Takashi Yamamoto; Koichi Kato; Kazutoshi Mori
        GLYCOBIOLOGY, Nov. 2014
      • The Antipsychotic Olanzapine Induces Apoptosis in Insulin-secreting Pancreatic beta Cells by Blocking PERK-mediated Translational Attenuation (vol 38, pg 183, 2013)
        R. Ozasa; T. Okada; S. Nadanaka; T. Nagamine; A. Zyryanova; H. Harding; D. Ron; K. Mori
        CELL STRUCTURE AND FUNCTION, 2014
      • 小胞体ストレス応答発動因子ATF6α/βの生理的役割の解析
        石川時郎; 岡田徹也; 藤原(石川)智子; 藤堂剛; 亀井保博; 重信秀治; 田中実; 斎藤太郎; 吉村淳; 森下真一; 豊田敦; 榊佳之; 谷口善仁; 武田俊一; 森和俊
        日本生化学会大会(Web), 2013
      • The endoplasmic reticulum stress sensor, ATF6 alpha, protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced dopaminergic neuronal death in a p38 Mitogen-Activated Protein Kinase dependent manner
        Naohiro Egawa; Keisuke Yamamoto; Haruhisa Inoue; Katsunori Nishi; Kazutoshi Mori
        NEUROSCIENCE RESEARCH, 2010
      • パーキンソン病における小胞体ストレスセンサーATF6αの機能
        江川 斉宏; 山本 敬祐; 井上 治久; 植村 健吾; 小川 智; 西 克典; 森 和俊; 高橋 良輔
        臨床神経学, Dec. 2009
      • The role of ER stress sensor ATF6 alpha in the pathogenesis of Parkinson's disease
        Naohiro Egawa; Keisuke Yamamoto; Haruhisa Inoue; Katsunori Nishi; Kazutoshi Mori; Ryosuke Takahashi
        NEUROSCIENCE RESEARCH, 2009
      • パ エル受容体による小胞体ストレスに対する小胞体ストレスマーカーATF6の関与
        江川斉宏; 山本敬祐; 井上治久; 植村健吾; 小川智; 森和俊; 高橋良輔
        49th Annual Meeting of the Japanese Society of Neurology, Yokohama., 15 May 2008
      • 小胞体関連分解構成因子Derlinsに結合するタンパク質の同定と解析
        NINAGAWA SATOSHI; OKADA TETSUYA; ODA YUKAKO; OKAWA KATSUYA; MORI KAZUTOSHI
        生化学, 2007
      • Functional analysis of the exocytic pathway in XBP1-transduced fibroblasts
        Gerald L. Buldak; Rungtawan Sriburi; Suzanne Jackowski; Kazutoshi Mori; Joseph W. Brewer
        JOURNAL OF IMMUNOLOGY, Apr. 2006
      • Role of Derlins in ER-associated degradation of misfolded proteins from the ER to the cytosol
        Yukako Oda; Tetsuya Okada; Hiderou Yoshida; Kazuhiro Nagata; Kazutoshi Mori
        The Joint Symposium of the IVR 50th Anniversary Symposium and The 2nd International Symposium of the Institute Network, 2006
      • Analisis of the unfolded protein response : an intracellular signaling pathway from the endoplasmic reticulum to the nucleus
        MORI Kazutoshi
        生化学, 25 Jul. 1998

      Books and Other Publications

      • Molecular Biology inside the Cell
        MORI Kazutoshi, Single work, all
        Kodansha-bluebacks, May 2016, Not refereed

      Awards

      • 25 Jan. 2024
        BBVA Foundation Frontiers of Knowledge Award
      • 09 Nov. 2023
        第２８回慶應医学賞
      • 22 Sep. 1997
        the Japanese Biochemical Society, Young Investigator Award
      • 08 Apr. 2005
        Wiley Foundation, Wiley Prize
      • 27 Oct. 2006
        the Japanese Biochemical Society, Investigator Award
      • 29 Oct. 2008
        Osaka Prefecture, Osaka City, Osaka Science Award
      • 29 Oct. 2009
        Gairdner Foundation, Canada Gairdner International Award
      • 29 Apr. 2010
        Emperor, Purple Medal
      • 09 Mar. 2012
        The Uehara Memorial Foundation, Uehara Prize
      • 30 Jan. 2014
        Asahi Shimbun Foundation, Asahi Prize
      • 19 Sep. 2014
        Lasker Foundation, Lasker Basic Medical Research Award
      • 24 Sep. 2014
        Shaw Prize Foundation, Shaw Prize in Life Science and Medicine
      • 03 Nov. 2014
        Kurashiki City, Honor Award of Kurashiki City
      • 08 Jan. 2015
        Sanyo Shimbun, Sanyo Shimbun Award
      • 16 Sep. 2015
        Cell Stress Society International, Medal
      • 24 Sep. 2015
        Thomson Reuters, Citation Laureate
      • 14 Dec. 2015
        Kyoto University, 孜孜賞
      • 12 Feb. 2016
        Okayama Prefecture, 文化特別顕彰
      • 27 Jun. 2016
        Japan Academy, Imperial Prize and Japan Academy Prize
      • 20 Apr. 2017
        The Japan Endocrine Society, Meister Prize
      • 31 Aug. 2017
        岡山県, 三木記念賞
      • 03 Dec. 2017
        Breakthrough Foundation, Breakthrough Prize
      • 05 Nov. 2018
        MEXT, Bunka-korosya
      • 12 Mar. 2019
        Ando Foundation, Ando Momofuku Prize

      External funds: Kakenhi

      • Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        Kazutoshi Mori
        From 30 Jun. 2017, To 31 Mar. 2022, Project Closed
        オルガネラ;オルガネラ・ゾーン;小胞体;輸送;タンパク質分解;小胞体ストレス;超解像顕微鏡;ゴルジ体;小胞輸送;選別;応答
        https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-17H06419/
      • Toward an integrative understanding of functional zones in organelles
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Tokyo Medical and Dental University
        Shigeomi Shimizu
        From 30 Jun. 2017, To 31 Mar. 2022, Project Closed
        オルガネラ;小胞体;ゴルジ体;ミトコンドリア;ゾーン;細胞生物;エンドソーム;超解像顕微鏡
        https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-17H06413/
      • Analysis of recognition mechanisms of misfoled proteins accumulated in the endoplasmic reticulum
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Kazutoshi Mori
        From 01 Apr. 2017, To 31 Mar. 2020, Project Closed
        構造異常タンパク質;認識;分解;小胞体ストレス応答;小胞体関連分解;小胞体;強制分解;認識機構
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H01432/
      • Elucidation of regulation mechanism of the endoplasmic reticulum membrane-bound transcription factor ATF6 and its role in the evolution of vertebrates
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Kazutoshi Mori
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        タンパク質品質管理;小胞体;転写因子;分子シャペロン;小胞体関連分解;ゴルジ体;エスコート;進化;細部内情報伝達;小胞体ストレス;小胞輸送;膜結合性転写因子;エスコートタンパク質
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26291040/
      • Physiological and pathological role of the endoplasmic reticulum stress transducer protein ATF6beta
        Grant-in-Aid for Scientific Research (B)
        The University of Tokushima
        Seiichi OYADOMARI
        From 01 Apr. 2013, To 31 Mar. 2017, Project Closed
        分子病態学;小胞体ストレス;ATF6
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25293080/
      • Analysis of molecular mechanism of sensing endoplasmic reticulum stress and effect of failing in the endoplasmic reticulum stress response
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Kazutoshi MORI
        From 01 Apr. 2008, To 31 Mar. 2011, Project Closed
        小胞体;分子シャペロン;転写誘導;膜結合性転写因子;ノックアウトマウス;選別輸送;還元;脂肪滴;アポリポプロテイン;心不全
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20247026/
      • Pathophysiological Role of ER-Ubiquitin/Proteasome System in Cardiovascular Remodeling
        Grant-in-Aid for Scientific Research (C)
        Osaka University
        Tetsuo MINAMINO
        From 01 Apr. 2007, To 31 Mar. 2009, Project Closed
        小胞体ストレス;心不全;心不全指標;プロテアソーム;心筋虚血;動脈硬化;CHOP;冠動脈プラーク破綻
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19590815/
      • Maintenance of the endoplasmic reticulum function by the unfolded protein response (UPR)
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kyoto University
        Kazutoshi MORI
        From 01 Apr. 2007, To 31 Mar. 2012, Project Closed
        小胞体;高次構造形成;分子シャペロン;タンパク質分解;品質管理;転写誘導;翻訳抑制;遺伝子ノックアウト;メダカ;初期発生;脊索;ニワトリ細胞;オルガネラ;スプライシング;翻訳;転写;脂質;プロテアソーム;分解;フォールディング;転写透導;オルガネラ形成;生体膜;リン脂質;B細胞分化
        https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-19058009/
      • Integrated promotion of the researches in protein community
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Nagoya University
        Toshiya ENDO
        From 01 Apr. 2007, To 31 Mar. 2013, Project Closed
        タンパク質;機能発現;品質管理;分子シャペロン;トランスロケータ;UPR;アミロイド;ERAD
        https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-19058006/
      • Dynamics of the function and regulation of the endoplasmic reticulum
        Grant-in-Aid for Creative Scientific Research
        Kyoto University
        Mori KAZUTOSHI
        From 01 Apr. 2003, To 31 Mar. 2008, Project Closed
        小胞体;転写因子;ゴルジ装置;プロテオリシス;ノックアウトマウス;胚性線維芽細胞;ストレス感知;還元;膜結合性転写因子;分子シャペロン;プロテアーゼ;ジスルフィド結合;酸化還元;アラニン置換;核;情報伝達;細胞内輸送;プロテアーゼ阻害剤;スプライシング, endoplasmic reticulum;transcription factor;Golgi apparatus;proteolysis;knockout mice;embryonic fibroblast;stress sensing;reduction
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15GS0310/
      • 小胞体膜結合性転写因子ATF6の細胞内ダイナミックス
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        森 和俊
        From 01 Apr. 2002, To 31 Mar. 2004, Project Closed
        小胞体;膜結合性転写因子;分子シャペロン;プロテオリシス;セリンプロテアーゼ;メタロプロテアーゼ;細胞内輸送;フォールディング
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14380335/
      • Analysis of an intracellular signaling from the endoplasmic reticulum to the nucleus
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kyoto University
        Kazutoshi MORI
        From 01 Apr. 2002, To 31 Mar. 2007, Project Closed
        分子シャペロン;小胞体;折り畳み;分解;転写誘導;プロテアーゼ;mRNAスプライシング;品質管理;変異株;膜タンパク質;マイクロアレイ解析;転写因子;酵素;巻き戻し;核;ゴルジ装置;情報伝達;細胞内輸送;プロテアーゼ阻害剤;タンパクの品質管理;フォールディング;ユビキチン;プロテアソーム, molecular chaperone;endoplasmic reticulum;folding;degradation;transcriptional induction;protease;mRNA splicing;quality control
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14037233/
      • ウィルス感染と宿主小胞体ストレス応答-ウィルスの増殖と細胞死との分岐点の解析
        Grant-in-Aid for Scientific Research on Priority Areas (C)
        Biological Sciences
        Kyoto University
        森 和俊
        From 01 Apr. 2001, To 31 Mar. 2002, Project Closed
        ウィルス;ストレス;小胞体;転写誘導;アポトーシス;ミトコンドリア;マクロファージ;一酸化窒素
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13226050/
      • Life of proteins: maturation, translocation, quality control in the cell
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Tokyo Institute of Technology
        Masasuke YOSHIDA
        From 01 Apr. 2001, To 31 Mar. 2008, Project Closed
        タンパク質;分子シャペロン;品質管理;タンパク質分解;小胞体;ミトコンドリア;タンパク質分泌;小胞体ストレス;蛋白質の膜透過;プリオン;ERAD;外膜リポタンパク質;ジスルフィド形成;ATP依存性プロテアーゼ;ストレス;シャペロン;成熟;輸送;生物物理;蛋白質;フォールディング;シャペロニン;タンパク質の膜透過, molecular chperone;ER stress;translocation;prion;ERAD;lipoprobin;disulfidebond formation;ATP dependent protease
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13053101/
      • Analysis of the UPR, a transcriptional induction process coupled with intracellular signaling from the endoplasmic reticulum to the nucleus
        Grant-in-Aid for Scientific Research (C)
        KYOTO UNIVERSITY
        Kazutoshi MORI
        From 01 Apr. 2000, To 31 Mar. 2002, Project Closed
        小胞体;分子シャペロン;フォールディング酵素;情報伝達;転写誘導;膜結合性転写因子;プロテオリシス;核移行;転写因子;マイクロアレー;アルツハイマー病;プレセニリン;フォールディング, endoplasmic reticulum;molecular chaperone;folding enzymes;intracellular signaling;transcriptional induction;transcription factor;proteolysis;nuclear translocation
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680692/
      • 神経ネットワーク形成における低分子量G蛋白質の役割
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Biological Sciences
        Kyoto University
        根岸 学
        From 01 Apr. 2000, To 31 Mar. 2001, Project Closed
        Rho;Rnd;Rac;Cdc42;NGF;PC12細胞;神経突起;神経回路
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12053244/
      • Development of the Enzyme Immunoassay Systems for the Substances Involved in the Cause of Alzheimer's Disease
        Grant-in-Aid for Developmental Scientific Research
        Gifu Pharmaceutical University
        Kyozo HAYASHI
        From 01 Apr. 1988, To 31 Mar. 1990, Project Closed
        高齢化社会;老人痴呆症;早期診断法;酵素免疫測定法;神経成長因子;上皮細胞増殖因子;ス-パ-オキシドディスムタ-ゼ;コリン作動性ニュ-ロン;老人痴呆塩;抗体;診断;神経成長促進因子;線維芽細胞成長因子;アミロイド蛋白;老人痴呆;測定感度;早期診断, Alzhermer's disease;cholinergic nerve cells;nerve growth factor (NGF);superoxide dismutase (SOD);enzyme immunoassay system (EIA);antibody;diagnosis;astoglial cells
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63870036/
      • Biochemical Studies on the Molecular Mechanism of Neurotransmission, Centered on Nicotinic Acetylcholine Receptor (nAChR)
        Grant-in-Aid for General Scientific Research (B)
        Gifu Pharmaceutical University
        Kyozo HAYASHI
        From 01 Apr. 1988, To 31 Mar. 1990, Project Closed
        ニコチン性アセチルコリン受容体;神経伝達;43K蛋白質;リン酸化;脱感作;糖鎖;プロテインキナ-ゼ;クレアチンキナ-ゼ;神経筋接合部;機能発見;コリン性リガンド;43kタンパク質;架橋形成;分子機構;ヘビ神経毒;リン酸化チロシン;43κ蛋白;キナーゼ, Nicotinic Acetylcholine Receptor (nAChR);Glycoprotein;Function;Phosphorylation;Carbohydrate Structure;43KDa Proteins;Desensitization;Neurotransmission
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63480218/
      • Studies on drug delivery and imaging for tumors by use of monoclonal antibodies against membrane enzymes
        Grant-in-Aid for General Scientific Research (C)
        Gifu Pharmaceutical University
        Kazuyuki HIRANO
        From 01 Apr. 1987, To 31 Mar. 1989, Project Closed
        アルカリフォスファターゼ;睾丸腫瘍;卵巣癌;イメージング;モノクローナル抗体;アルカリフォスファタゼ;ミサイル療法, Alkaline phosphatase;testicular tumor;ovarian cancer;imaging
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-62570993/
      • Biochemical Studies on the Mechanism of Neurotransmission--- Principally Structure-Function Relationship of Nicotinic Acetylcholine Receptor ---
        Grant-in-Aid for General Scientific Research (A)
        Gifu Pharmaceutical University
        Kyozo HAYASHI
        From 01 Apr. 1986, To 31 Mar. 1988, Project Closed
        ニコチン性アセチルコリン受容体;神経伝達;糖鎖構造;ハイマンノース型;分子量43,000蛋白群;プロテインキナーゼ;クレアチンキナーゼ;ヘビ神経毒;ニコチン性アセチルコリン受容体(AChR);糖鎖;ハイマンノース型糖鎖;コンプレックス型糖鎖;コリン性ガンド;αブンガロトキシン;シビレエイ;43k蛋白, Nicotinic Acetylcholine Receptor (nAChR); Neurotransmission;Carbohydrate Structure;High-Mannose Type;Molecular Weight 43,000 Proteins;Protein Kinase;Creatine Kinase
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61440085/
      • 哺乳動物の小胞体関連分解における小胞体内イベントの全容解明
        Grant-in-Aid for Scientific Research (A)
        Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
        Kyoto University
        森 和俊
        From 01 Apr. 2022, To 31 Mar. 2025, Granted
        小胞体関連分解;構造異常の度合い;オルガネラ
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H00407/

      External funds: others

      • Quality control of proteins in the endoplasmic reticulum
        CREST
        From 2001, To 31 Mar. 2003
        永田和宏
      • Analysis of gene network in Parkinson disease and its cure strategy
        CREST
        From 2007, To 31 Mar. 2013
        高橋良輔
      • Structural analysis of ER stress response mediators
        タンパク3000
        From 2002, To 31 Mar. 2007
        三木邦夫
      • Study on understanding of the molecular mechanisms of tissue-specific unfolded protein responses for radical cure of human chronic diseases
        AMED-CREST
        From 01 Oct. 2020, To 31 Mar. 2016
        森和俊
      • Quality control of proteins in the endoplasmic reticulum
        未来開拓学術研究推進事業
        From 2000, To 31 Mar. 2002
        代表
      list
        Last Updated :2025/05/02

        Education

        Teaching subject(s)

        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Biophysics
          N488, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IC
          9047, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IB
          9046, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IA
          9045, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IIB
          9050, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IIA
          9049, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information ID
          9048, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IID
          9052, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Expression of Genomic Information IIC
          9051, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Laboratory work in Biological Science A
          3762, Spring, Faculty of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Signaling inside the cell
          3757, Spring, Faculty of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Cell Biology
          2706, Spring, Faculty of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Molecular Biology I
          2702, Spring, Faculty of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Course on Biological Science A
          9011, Spring, Graduate School of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Course for Expression of Genomic Information
          9004, Spring, Graduate School of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Fundamental Experiments of Cellular and Molecular Biology
          2729, Fall, Faculty of Science, 4
        • From 01 Apr. 2022, To 31 Mar. 2023
          Laboratory work in Biological Science A
          3762, Spring, Faculty of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Molecular Biology I
          2702, Spring, Faculty of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IIC
          9051, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IB
          9046, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminars in Biological Science B
          4732, Fall, Faculty of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IID
          9052, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IIA
          9049, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IA
          9045, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Course for Expression of Genomic Information
          9004, Spring, Graduate School of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information ID
          9048, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Introduction to Biophysics
          N488, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Course on Biological Science A
          9011, Spring, Graduate School of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Course on Biological Science B
          9012, Fall, Graduate School of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Special Study CourseII(Biological Sciences) 17
          8720, Year-long, Faculty of Science, 12
        • From 01 Apr. 2022, To 31 Mar. 2023
          Cell Biology
          2706, Spring, Faculty of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Signaling inside the cell
          3757, Spring, Faculty of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IC
          9047, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Expression of Genomic Information IIB
          9050, Fall, Graduate School of Science, 1
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学特論
          Spring, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅠＡ
          Spring, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅠＢ
          Fall, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅠＣ
          Spring, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅠＤ
          Fall, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅡＡ
          Spring, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅡＢ
          Fall, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅡＣ
          Spring, 理学研究科
        • From Apr. 2011, To Mar. 2012
          ゲノム情報発現学ゼミナールⅡＤ
          Fall, 理学研究科
        • From Apr. 2011, To Mar. 2012
          細胞内情報発信学
          Spring, 理学部
        • From Apr. 2011, To Mar. 2012
          生物学実習Ａ　（２）
          Spring, 理学部
        • From Apr. 2011, To Mar. 2012
          生物学セミナ－Ｂ　（１２）
          Fall, 理学部
        • From Apr. 2011, To Mar. 2012
          生物科学課題研究１７
          Year-long, 理学部
        • From Apr. 2011, To Mar. 2012
          分子生物学II
          Fall, 理学部
        • From Apr. 2011, To Mar. 2012
          分子生物学Ｉ
          Spring, 理学部
        • From Apr. 2011, To Mar. 2012
          Biophysical Basis of Biological Phenomena
          Spring, 全学共通科目
        • From Apr. 2011, To Mar. 2012
          細胞生物学
          Spring, 理学部
        • From Apr. 2012, To Mar. 2013
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2012, To Mar. 2013
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2012, To Mar. 2013
          Biophysical Basis of Biological Phenomena
          Spring, 全学共通科目
        • From Apr. 2012, To Mar. 2013
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2012, To Mar. 2013
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2012, To Mar. 2013
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2012, To Mar. 2013
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2012, To Mar. 2013
          Cell Biology
          Spring, 理学部
        • From Apr. 2013, To Mar. 2014
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2013, To Mar. 2014
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2013, To Mar. 2014
          Cell Biology
          Spring, 理学部
        • From Apr. 2013, To Mar. 2014
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2013, To Mar. 2014
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2013, To Mar. 2014
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2013, To Mar. 2014
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2013, To Mar. 2014
          Biophysical Basis of Biological Phenomena
          Spring, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2014, To Mar. 2015
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2014, To Mar. 2015
          Cell Biology
          Spring, 理学部
        • From Apr. 2014, To Mar. 2015
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2014, To Mar. 2015
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2014, To Mar. 2015
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2014, To Mar. 2015
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2014, To Mar. 2015
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2014, To Mar. 2015
          Biophysical Basis of Biological Phenomena
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2015, To Mar. 2016
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2015, To Mar. 2016
          Biophysical Basis of Biological Phenomena
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Frontiers of Biology
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2015, To Mar. 2016
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2015, To Mar. 2016
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2015, To Mar. 2016
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2015, To Mar. 2016
          Cell Biology
          Spring, 理学部
        • From Apr. 2016, To Mar. 2017
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2016, To Mar. 2017
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Frontiers of Biology
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2016, To Mar. 2017
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2016, To Mar. 2017
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Course on Biological Science B
          Fall, 理学研究科
        • From Apr. 2016, To Mar. 2017
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2016, To Mar. 2017
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2016, To Mar. 2017
          Cell Biology
          Spring, 理学部
        • From Apr. 2017, To Mar. 2018
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2017, To Mar. 2018
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Frontiers of Biology
          Spring, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2017, To Mar. 2018
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2017, To Mar. 2018
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Course on Biological Science B
          Fall, 理学研究科
        • From Apr. 2017, To Mar. 2018
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2017, To Mar. 2018
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2017, To Mar. 2018
          Cell Biology
          Spring, 理学部
        • From Apr. 2018, To Mar. 2019
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2018, To Mar. 2019
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2018, To Mar. 2019
          Experimental Course of Fundamental Biology II
          Fall, 理学部
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2018, To Mar. 2019
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2018, To Mar. 2019
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          Inter Lab Studies, Biological Science
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Course on Biological Science B
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2018, To Mar. 2019
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2018, To Mar. 2019
          Cell Biology
          Spring, 理学部
        • From Apr. 2019, To Mar. 2020
          Molecular Biology II
          Fall, 理学部
        • From Apr. 2019, To Mar. 2020
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2019, To Mar. 2020
          Laboratory work in Biological Science A
          Spring, 理学部
        • From Apr. 2019, To Mar. 2020
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Course on Biological Science B
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2019, To Mar. 2020
          Signaling inside the cell
          Spring, 理学部
        • From Apr. 2019, To Mar. 2020
          Cell Biology
          Spring, 理学部
        • From Apr. 2020, To Mar. 2021
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2020, To Mar. 2021
          Laboratory Work in Biological Science A
          Spring, 理学部
        • From Apr. 2020, To Mar. 2021
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Course on Biological Science B
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2020, To Mar. 2021
          Signaling Inside the Cell
          Spring, 理学部
        • From Apr. 2020, To Mar. 2021
          Cell Biology
          Spring, 理学部
        • From Apr. 2021, To Mar. 2022
          Molecular Biology I
          Spring, 理学部
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IA
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IB
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IC
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information ID
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IIA
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IIB
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IIC
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Expression of Genomic Information IID
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Course for Expression of Genomic Information
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminars in Biological Science B
          Fall, 理学部
        • From Apr. 2021, To Mar. 2022
          Laboratory Work in Biological Science A
          Spring, 理学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Biophysics
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Advanced Course on Biological Science A
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Special Study CourseII(Biological Sciences) 17
          Year-long, 理学部
        • From Apr. 2021, To Mar. 2022
          Signaling Inside the Cell
          Spring, 理学部
        • From Apr. 2021, To Mar. 2022
          Fundamental Experiments of Cellular and Molecular Biology
          Fall, 理学部
        • From Apr. 2021, To Mar. 2022
          Cell Biology
          Spring, 理学部

        Participation in PhD Defense

        • 小胞体膜結合性転写因子ATF6αとATF6βがヌードマウスにおける癌細胞増殖に及ぼす影響の解析
          JIN SHENGYU, Graduate School of Science, Chief Examiner
          23 May 2023
        • メダカにおける飢餓誘導性脂肪肝発症ならびにレトロトランスロコン構成因子欠失による発症促進の分子機構解析
          IKEDA TOMOYO, Graduate School of Science, Chief Examiner
          25 Mar. 2024
        • 運動神経変性疾患の原因となる無糖鎖型Seipinに起因する小胞体ストレスと細胞死の誘導機構の解析
          SAITO SHUNSUKE, Graduate School of Science, Chief Examiner
          23 Mar. 2023
        • シロイヌナズナPIP5K1、PIP5K2、PIP5K3遺伝子の機能分化の解析
          WATARI MACHIKO, Graduate School of Science, Sub-chief Examiner
          25 Jul. 2022
        • Molecular mechanism by which Djplac8-A controls proliferation/differentiation of planarian pluripotent stem cells during regeneration
          Lee Hayoung, Graduate School of Science, Chief Examiner
          23 May 2022
        • Functional analyses of Arabidopsis Cleavage Factor I
          Zhang Xiaojuan, Graduate School of Science, Sub-chief Examiner
          23 May 2022
        • シロイヌナズナにおけるPIP5K7,PIP5K8およびPIP5K9の機能解析
          KURODA RYO, Graduate School of Science, Sub-chief Examiner
          24 May 2021
        • Analysis of conformational space sampled by domain reorientation in linear diubiquitin by paramagnetic NMR
          HOU, XUENI, Graduate School of Science, Sub-chief Examiner
          24 Sep. 2021
        • SEL1Lの分解中間体はポリグルタミンタンパク質の細胞質での凝集を促進する
          HATTORI TOKUYA, Graduate School of Science, Sub-chief Examiner
          24 Jan. 2022
        • プラナリアにおける多能性幹細胞の移動・自己複製・分化の関連性の解析
          SATO YUKI, Graduate School of Science, Chief Examiner
          23 Mar. 2022

        Part-time lecturer

        • From 01 Oct. 2024, To 31 Mar. 2025
          岐阜薬科大学
        • From 01 Oct. 2023, To 31 Mar. 2024
          岐阜薬科大学
        • From 01 Oct. 2022, To 31 Mar. 2023
          岐阜薬科大学
        list
          Last Updated :2025/05/02

          Administration

          School management (title, position)

          • From 01 Apr. 2023, To 31 Mar. 2024
            国際高等教育院 企画評価専門委員会 生物学部会 委員
          • From 01 Apr. 2022
            国際高等教育院 企画評価専門委員会 委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            国際高等教育院 企画評価専門委員会 生物学部会 委員
          • From 01 Apr. 2022, To 31 Mar. 2024
            大学院教育支援機構 大学院共通・横断教育企画評価専門委員会 委員
          • From 01 Apr. 2020, To 31 Mar. 2022
            生物科学系 学系長
          • From 01 Apr. 2016, To 31 Mar. 2018
            京都大学教務事務電算管理運営委員会 委員
          • From 11 Sep. 2015, To 31 Dec. 2015
            ヒトゲノム・遺伝子解析研究管理委員会 委員
          • From 11 Sep. 2013, To 10 Sep. 2015
            ヒトゲノム・遺伝子解析研究管理委員会 委員
          • From 11 Sep. 2011, To 10 Sep. 2013
            京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員
          • From 11 Sep. 2009, To 10 Sep. 2013
            京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員
          • From 01 Oct. 2008, To 30 Sep. 2010
            京都大学動物実験委員会 委員
          • From 01 Apr. 2008, To 31 Mar. 2011
            京都大学ヒトゲノム・遺伝子解析研究管理委員会 委員
          • From 01 Apr. 2008, To 31 Mar. 2011
            基礎教育専門委員会 委員

          Faculty management (title, position)

          • From 01 May 2024, To 31 Mar. 2025
            高等研究院 副院長
          • From 01 Apr. 2023, To 31 Mar. 2024
            理学部・教育委員会 委員
          • From 01 Apr. 2023, To 31 Mar. 2024
            理学部・教育委員会 全学共通教育委員会 委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学研究科研究科会議 構成員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学部・教育委員会 全学共通教育委員会 委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学部・教育委員会 常任委員会 委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学部・教育委員会 委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学部・教育委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学部・教育委員会　常任委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学研究科大学院教育常任委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学研究科研究科会議構成員
          • From 01 Apr. 2020, To 31 Mar. 2021
            理学部・教育委員会委員
          • From 01 Apr. 2020, To 31 Mar. 2021
            理学部・教育委員会　常任委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学部・教育委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学部・教育委員会　常任委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学部・教育委員会　入試専門小委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            特色入試実施委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学研究科大学院教育常任委員会委員
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学研究科大学院教育教務委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科生物科学専攻長
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科将来計画委員会・常任委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科動物実験委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科研究科会議構成員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科専攻長会議構成員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科兼業委員会委員
          • From 01 Apr. 2017, To 31 Mar. 2018
            理学研究科将来計画委員会委員
          • From 01 Apr. 2017, To 31 Mar. 2018
            理学研究科会議構成員
          • From 01 Apr. 2016, To 31 Mar. 2017
            理学部・教育委員会委員
          • From 01 Apr. 2016, To 31 Mar. 2017
            理学部・教育委員会　常任委員会委員
          • From 01 Apr. 2016, To 31 Mar. 2017
            理学部・教育委員会　教務委員会委員
          • From 01 Apr. 2016, To 31 Mar. 2017
            理学研究科相談室運営委員会委員
          • From 01 Apr. 2016, To 31 Mar. 2018
            理学研究科相談室運営委員会委員
          • From 01 Apr. 2015, To 31 Mar. 2016
            生物科学専攻長
          • From 01 Apr. 2015, To 31 Mar. 2016
            理学研究科動物実験委員会委員
          • From 01 Apr. 2015, To 31 Mar. 2016
            理学研究科相談室運営委員会委員
          • From 01 Apr. 2015, To 31 Mar. 2016
            理学研究科会議構成員
          • From 01 Apr. 2014, To 31 Mar. 2015
            理学研究科将来計画委員会委員
          • From 01 Apr. 2014, To 31 Mar. 2015
            理学研究科将来計画委員会・理学研究科研究機器開発支援室運営委員会委員
          • From 01 Apr. 2014, To 31 Mar. 2015
            理学研究科情報セキュリティ委員会委員
          • From 01 Apr. 2014, To 31 Mar. 2015
            理学研究科会議構成員

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