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Kohjitani, Hirohiko

Graduate School of Medicine Program-Specific Senior Lecturer/Program-Specific Junior Associate Professor

Kohjitani, Hirohiko
list
    Last Updated :2025/06/08

    Basic Information

    Professional Memberships

    • From Feb. 2021, To Present
      日本SIDS･乳幼児突然死予防学会
    • From Apr. 2017, To Present
      The Physiolosical Society of Japan
    • From Apr. 2012, To Present
      Japanese Heart Rhythm Society
    • From Apr. 2011, To Present
      The Japanese Circulation Society
    • From Oct. 2010, To Present
      The Japanese Society of Internal Medicine
    • From May 2019, To Present
      The Japanese Society for Artificial Intelligence

    Academic Degree

    • 京都大学博士（医学）

    Research History

    • From Jun. 2021, To Present
      Kyoto University Hospital, Department of Cardiovascular Medicine, Medical Doctor
    • From Apr. 2025, To Present
      Kyoto University, Graduate School of Medicine, Lecturer
    • From Apr. 2014, To Mar. 2018
      Kyoto University Hospital, Department of Cardiovascular Medicine, 非常勤医師
    • From Jun. 2021, To Mar. 2025
      Kyoto University, Graduate School of Medicine, Associate Professor
    • From Apr. 2018, To May 2021
      Kyoto University Hospital, Department of Cardiovascular Medicine, Medical Doctor
    • From Apr. 2011, To Mar. 2014
      Kobe City Medical Center General Hospital, Department of Cardiovascular Medicine, Senior Resident
    • From Apr. 2009, To Mar. 2011
      Tazuke Kofukai Foundation, Medical Research Institute, Medical Department, Junior Resident

    Profile

    • Profile

      Cardiologist, Arrhythmia, Catheter ablation
      Computer simulation, Mathematical modeling, Ion-channels, hiPSC-CMs

    Language of Instruction

    • Japanese
    • English

    ID,URL

    researchmap URL

    list
      Last Updated :2025/06/08

      Research

      Research Interests

      • Machine Learning
      • Medical artificial intelligence
      • Mathematical Optimization
      • Cardiology
      • Catheter ablation
      • genetic arrhythmia
      • human induced pluripotent stem cell derived
      • computer simulation
      • cell electrophysiology

      Research Areas

      • Life sciences, Cardiology

      Papers

      • Sex-specific clinical course of young patients with Brugada syndrome
        Tomohiko Imamura; Takeru Makiyama; Junichi Ozawa; Keiko Sonoda; Koichi Kato; Takanori Aizawa; Asami Kashiwa; Jingshan Gao; Hai Huang; Yuta Yamamoto; Hirohiko Kohjitani; Hisaaki Aoki; Seiichi Watanabe; Shota Muraji; Takuro Kojima; Masao Yoshinaga; Seiko Ohno; Hiroshi Suzuki; Naokata Sumitomo; Yoshihisa Nakagawa; Koh Ono; Minoru Horie; Takeshi Kimura
        European Heart Journal, 05 Feb. 2025, Peer-reviewed
      • Serial Optical Coherence Tomography Assessment of Coronary Atherosclerosis and Long-Term Clinical Outcomes.
        Kyohei Yamaji; Kenji Kanenawa; Toru Morofuji; Ryusuke Nishikawa; Kazuaki Imada; Hirohiko Kohjitani; Hiroki Watanabe; Junichi Tazaki; Masanori Taniwaki; Seiji Koga; Ryohei Akashi; Shunsuke Kubo; Masanobu Ohya; Tatsuo Kikuchi; Hiroshi Ohira; Yohei Numasawa; Masaya Arikawa; Makoto Iwama; Takeshi Kitai; Yohei Kobayashi; Hiroki Shiomi; Tomohisa Tada; Yuhei Yamaji; Hyuma Daidoji; Hayato Ohtani; Yutaka Furukawa; Kazushige Kadota; Mamoru Toyofuku; Kenji Ando; Koh Ono; Takeshi Kimura
        Journal of the American Heart Association, 22 Oct. 2024, Peer-reviewed
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      • Comparison of Feature Extraction Methods for Prognosis Prediction in Hereditary Arrythmia Disease
        三谷孟司; 三谷孟司; 岡本有司; 糀谷泰彦; 糀谷泰彦; 相澤卓範; 牧山武; 牧山武; 大野聖子; 堀江稔; 奥野恭史
        人工知能学会全国大会論文集(Web), 11 Jun. 2024, Peer-reviewed
      • Prevalence and characteristics of atrioventricular nodal reentrant tachycardia with a bystander concealed nodoventricular/nodofascicular pathway.
        Shushi Nishiwaki; Satoshi Shizuta; Tomoyuki Inoue; Akifumi Morinaga; Fumiya Yoneda; Munekazu Tanaka; Takanori Aizawa; Hirohiko Kohjitani; Koh Ono
        Heart rhythm, 26 Jun. 2024, Peer-reviewed
      • Development of interpretable machine learning models to predict in-hospital prognosis of acute heart failure patients.
        Munekazu Tanaka; Hirohiko Kohjitani; Erika Yamamoto; Takeshi Morimoto; Takao Kato; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Masayuki Shiba; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Yasushi Okuno; Takeshi Kimura; Koh Ono
        ESC heart failure, 15 May 2024, Peer-reviewed
      • Insight from the microelectrodes in case of two different types of premature ventricular contractions originating from left ventricular summit
        Shushi Nishiwaki; Satoshi Shizuta; Hirohiko Kohjitani; Koh Ono
        Indian Pacing and Electrophysiology Journal, May 2024, Peer-reviewed
      • Recent developments in machine learning modeling methods for hypertension treatment.
        Hirohiko Kohjitani; Hiroshi Koshimizu; Kazuki Nakamura; Yasushi Okuno
        Hypertension research : official journal of the Japanese Society of Hypertension, 12 Jan. 2024, Peer-reviewed, Lead author, Corresponding author
      • Successful cardiac synchronization therapy device upgrade using an active fixation quadripolar pacing lead in a patients with persistent left superior vena cava and absent right superior vena cava.
        Shushi Nishiwaki; Satoshi Shizuta; Munekazu Tanaka; Hirohiko Kohjitani; Koh Ono
        Journal of arrhythmia, Oct. 2023, Peer-reviewed
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      • 致死性不整脈に対するアミオダロン静注から内服への切り替え状況の検討
        糀谷 泰彦; 小堀 敦志; 羽渓 健; 豊田 俊彬; 井手 裕也; 本田 怜史; 西野 共達; 金 基泰; 北井 豪; 江原 夏彦; 木下 愼; 加地 修一郎; 山室 淳; 谷 知子; 古川 裕
        Progress in Medicine, Mar. 2012, Lead author
      • Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
        Jingshan Gao; Takeru Makiyama; Yuta Yamamoto; Takuya Kobayashi; Hisaaki Aoki; Thomas L Maurissen; Yimin Wuriyanghai; Asami Kashiwa; Tomohiko Imamura; Takanori Aizawa; Hai Huang; Hirohiko Kohjitani; Misato Nishikawa; Kazuhisa Chonabayashi; Megumi Fukuyama; Hiromi Manabe; Kouichi Nakau; Tsutomu Wada; Koichi Kato; Futoshi Toyoda; Yoshinori Yoshida; Naomasa Makita; Knut Woltjen; Seiko Ohno; Nagomi Kurebayashi; Takashi Murayama; Takashi Sakurai; Minoru Horie; Takeshi Kimura
        Circulation. Arrhythmia and electrophysiology, 03 Mar. 2023, Peer-reviewed
      • Non-missense variants of KCNH2 show better outcomes in type 2 long QT syndrome.
        Takanori Aizawa; Yuko Wada; Kanae Hasegawa; Hai Huang; Tomohiko Imamura; Jingshan Gao; Asami Kashiwa; Hirohiko Kohjitani; Megumi Fukuyama; Koichi Kato; Eri Toda Kato; Takashi Hisamatsu; Seiko Ohno; Takeru Makiyama; Takeshi Kimura; Minoru Horie
        Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 02 Mar. 2023, Peer-reviewed
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      • AI development for hypertension therapy
        Hirohiko Kohjitani; Hiroshi Koshimizu; Kazuki Nakamura; Yasushi Okuno
        Nippon Rinsho, 2023, Peer-reviewed, Lead author
      • An irregularly irregular supraventricular tachycardia: What is the mechanism?
        Shushi Nishiwaki; Misaki Naka; Akifumi Morinaga; Fumiya Yoneda; Munekazu Tanaka; Hirohiko Kohjitani; Satoshi Shizuta
        Journal of cardiovascular electrophysiology, 13 Dec. 2022, Peer-reviewed
      • Impact of catheter ablation on functional tricuspid regurgitation in patients with atrial fibrillation.
        Shushi Nishiwaki; Shin Watanabe; Fumiya Yoneda; Munekazu Tanaka; Takanori Aizawa; Shintaro Yamagami; Akihiro Komasa; Tetsuma Kawaji; Takashi Yoshizawa; Hirohiko Kohjitani; Takeshi Morimoto; Takeshi Kimura; Satoshi Shizuta
        Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 13 Dec. 2022, Peer-reviewed
      • Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes.
        Hirohiko Kohjitani; Shigeya Koda; Yukiko Himeno; Takeru Makiyama; Yuta Yamamoto; Daisuke Yoshinaga; Yimin Wuriyanghai; Asami Kashiwa; Futoshi Toyoda; Yixin Zhang; Akira Amano; Akinori Noma; Takeshi Kimura
        Scientific reports, 09 Nov. 2022, Peer-reviewed, Lead author
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      • Disrupted Cav1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model.
        Asami Kashiwa; Takeru Makiyama; Hirohiko Kohjitani; Thomas L Maurissen; Taisuke Ishikawa; Yuta Yamamoto; Yimin Wuriyanghai; Jingshan Gao; Hai Huang; Tomohiko Imamura; Takanori Aizawa; Misato Nishikawa; Kazuhisa Chonabayashi; Hiroyuki Mishima; Seiko Ohno; Futoshi Toyoda; Seiichi Sato; Koh-Ichiro Yoshiura; Kazuhiro Takahashi; Yoshinori Yoshida; Knut Woltjen; Minoru Horie; Naomasa Makita; Takeshi Kimura
        Heart rhythm, 23 Aug. 2022, Peer-reviewed
      • Atrial pacing successfully suppressed drug-resistant ventricular fibrillation in a patient with early repolarization syndrome.
        Shushi Nishiwaki; Satoshi Shizuta; Munekazu Tanaka; Akihiro Komasa; Hirohiko Kohjitani; Takeshi Kimura
        HeartRhythm case reports, Jul. 2022, Peer-reviewed
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      • A case of preexcitation syndrome showing atypical atrioventricular nodal reentrant tachycardia and orthodromic atrioventricular reciprocating tachycardia with a bystander concealed nodoventricular/nodofascicular pathway.
        Shushi Nishiwaki; Satoshi Shizuta; Munekazu Tanaka; Akihiro Komasa; Hirohiko Kohjitani; Takeshi Kimura
        HeartRhythm case reports, Jul. 2022, Peer-reviewed
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      • Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society - Change Practice!
        Koh Ono; Satoshi Shizuta; Erika Yamamoto; Naritatsu Saito; Neiko Ozasa; Takao Kato; Eri Kato; Takahiro Horie; Junichi Tazaki; Hiroki Shiomi; Shin Watanabe; Hirotoshi Watanabe; Yugo Yamashita; Yusuke Yoshikawa; Hideyuki Kinoshita; Takeru Makiyama; Yoshinori Yoshida; Noboru Ashida; Yasuaki Nakagawa; Yasuhiro Nakashima; Osamu Baba; Hirohiko Kohjitani; Masahiro Kimura; Hideaki Inazumi; Takashi Yoshizawa; Akihiro Komasa; Takeshi Kimura
        Circulation journal : official journal of the Japanese Circulation Society, 25 Feb. 2021, Peer-reviewed
      • Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model
        Hirose Sayako; Makiyama Takeru; Melgari Dario; Melgari Dario; Yamamoto Yuta; Yamamoto Yuta; Wuriyanghai Yimin; Yokoi Fumika; Nishiuchi Suguru; Harita Takeshi; Hayano Mamoru; Kohjitani Hirohiko; Gao Jingshan; Kashiwa Asami; Nishikawa Misato; Wu Jie; Wu Jie; Yoshimoto Jun; Chonabayashi Kazuhisa; Ohno Seiko; Yoshida Yoshinori; Horie Minoru; Horie Minoru; Kimura Takeshi
        Frontiers in Cell and Developmental Biology (Web), 2020, Peer-reviewed
      • Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells
        Yoshinaga Daisuke; Baba Shiro; Makiyama Takeru; Shibata Hirofumi; Hirata Takuya; Akagi Kentaro; Matsuda Koichi; Kohjitani Hirohiko; Wuriyanghai Yimin; Umeda Katsutsugu; Yamamoto Yuta; Conklin Bruce R.; Conklin Bruce R.; Horie Minoru; Takita Junko; Heike Toshio
        Stem Cell Reports, 13 Aug. 2019, Peer-reviewed
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      • Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation
        Wuriyanghai Yimin; Wuriyanghai Yimin; Makiyama Takeru; Sasaki Kenichi; Kamakura Tsukasa; Yamamoto Yuta; Hayano Mamoru; Harita Takeshi; Nishiuchi Suguru; Chen Jiarong; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Gao Jingshan; Chonabayashi Kazuhisa; Watanabe Ken; Ohno Seiko; Ohno Seiko; Yoshida Yoshinori; Kimura Takeshi; Horie Minoru
        Heart Rhythm, Oct. 2018, Peer-reviewed
      • A hERG mutation E1039X produced a synergistic lesion on IKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations.
        Jie Wu; Yuka Mizusawa; Seiko Ohno; Wei-Guang Ding; Takashi Higaki; Qi Wang; Hirohiko Kohjitani; Takeru Makiyama; Hideki Itoh; Futoshi Toyoda; Andrew F James; Jules C Hancox; Hiroshi Matsuura; Minoru Horie
        Scientific reports, 15 Feb. 2018, Peer-reviewed
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      • Genetic-based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers
        NISHIUCHI Suguru; MAKIYAMA Takeru; AIBA Takeshi; NAKAJIMA Kenzaburo; HIROSE Sayako; KOHJITANI Hirohiko; YAMAMOTO Yuta; HARITA Takeshi; HAYANO Mamoru; SASAKI Kenichi; ISHIKAWA Taisuke; ONOUE Kenji; OHNO Seiko; SAITO Yoshihiko; KUSANO Kengo; MAKITA Naomasa; SHIMIZU Wataru; HORIE Minoru; KIMURA Takeshi
        Circulation: Cardiovascular Genetics, Dec. 2017, Peer-reviewed
      • Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N-Related Cardiac Sodium Channelopathy
        Hayano Mamoru; Makiyama Takeru; Kamakura Tsukasa; Watanabe Hiroshi; Sasaki Kenichi; Funakoshi Shunsuke; Wuriyanghai Yimin; Wuriyanghai Yimin; Nishiuchi Suguru; Harita Takeshi; Yamamoto Yuta; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Chen Jiarong; Baba Osamu; Horie Takahiro; Chonabayashi Kazuhisa; Ohno Seiko; Toyoda Futoshi; Yoshida Yoshinori; Ono Koh; Horie Minoru; Kimura Takeshi
        Circulation Journal, 24 Nov. 2017, Peer-reviewed
      • Allele-specific Ablation Rescues Electrophysiological Abnormalities in a Human iPS Cell Model of Long-QT Syndrome with a CALM2 Mutation
        YAMAMOTO Yuta; MAKIYAMA Takeru; HARITA Takeshi; SASAKI Kenichi; HAYANO Mamoru; NISHIUCHI Suguru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; ISHIKAWA Taisuke; MOTOMURA Hideki; OHNO Seiko; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        Human molecular genetics, 01 May 2017, Peer-reviewed
      • Patient-specific human induced pluripotent stem cell model assessed with electrical pacing validates S107 as a potential therapeutic agent for catecholaminergic polymorphic ventricular tachycardia
        Sasaki, Kenichi; Makiyama, Takeru; Wuriyanghai, Yimin; Wuriyanghai, Yimin; Kamakura, Tsukasa; Nishiuchi, Suguru; Hayano, Mamoru; Harita, Takeshi; Yamamoto, Yuta; Kohjitani, Hirohiko; Hirose, Sayako; Chen, Jiarong; Kimura, Takeshi; Yoshida, Yoshinori; Yamanaka, Shinya; Kawamura, Mihoko; Ohno, Seiko; Itoh, Hideki; Horie, Minoru; Takeuchi, Ayako; Matsuoka, Satoshi; Miura, Masaru; Sumitomo, Naokata
        PLoS ONE, 2016, Peer-reviewed
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      Misc.

      • 完全房室ブロックに対してペースメーカ植込み後,運動時のみT波オーバーセンスを生じ,次の心室ペーシングが脱落した1例
        西脇修司; 馬場大輔; 井上智之; 森永晃史; 米田史哉; 田中宗和; 畑玲央; 糀谷泰彦; 尾野亘
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2025
      • Classifying electrocardiogram with uncertainty-aware explanation
        SATO Noriaki; KOJIMA Ryosuke; KOHJITANI Hirohiko; UEDA Akihiko; SHIRAKI Atsuko; OKUNO Yasushi; IMOTO Seiya
        日本集中治療医学会学術集会(Web), 2024
      • EXAMINATION OF THE RESULTS OF EXPANDABLE CRYOBALLOON ABLATION FOR ATRIAL FIBRILLATION
        YONEDA Fumiya; INOUE Tomoyuki; MORINAGA Akifumi; TANAKA Munekazu; NISHIWAKI Shushi; KOJITANI Hirohiko; SHIZUTA Satoshi; ONO Ko
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2024
      • THE INVESTIGATION OF THE RECURRENCE OF BLOCKLINE AFTER CAVOTRICUSPID ISTHMUS ABLATIONUSING A 3D MAPPING SYSTEM
        INOUE Tomoyuki; TANAKA Munekazu; MORINAGA Akifumi; YONEDA Fumiya; NISHIWAKI Shushi; KOJITANI Hirohiko; SHIZUTA Satoshi; ONO Ko
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2024
      • Development of an Interpretable Prediction Model Based on Machine Learning for Worsening Heart Failure in Patients with Acute Heart Failure
        TANAKA Munekazu; KOHJITANI Hirohiko; YAMAMOTO Erika; KATO Takao; ONO Koh
        日本循環器学会学術集会(Web), 2024
      • VISUALIZATION OF EPICARDIAL CONDUCTION IN PERI-MITRAL ATRIAL TACHYCARDIA USING A 3D MAPPING SYSTEM
        TANAKA Munekazu; SHIZUTA Satoshi; INOUE Tomoyuki; MORINAGA Akifumi; YONEDA Fumiya; NISHIWAKI Shushi; KOJITANI Hirohiko; ONO Ko
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2024
      • ARTIFICIAL INTELLIGENCE MODEL FOR EXTRACTING LEFT ATRIUM FROM NON-CONTRAST CT USING DEEP LEARNING
        TAKAZAWA Sorato; KOJITANI Hirohiko; KOJITANI Hirohiko; UEDA Akihiko; SHIZUTA Satoshi; ONO Ko; OKUNO Yasushi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2024
      • Post-discharge Use of Tolvaptan in Patients with Heart Failure as a Predictor of 2-year Rehospitalization: Explainable Artificial-Intelligence Based Study
        糀谷泰彦; 糀谷泰彦; 糀谷泰彦; 山本絵里香; 内野詠一郎; 田中宗和; 瀬尾拓哉; 仲山加奈子; 高野橋健太; 尾野亘; 奥野恭史; 奥野恭史
        日本循環器学会学術集会(Web), 2024
      • 化学的アブレーション後に左横隔神経不全麻痺をきたした1例
        森永晃史; 静田聡; 西脇修司; 井上智之; 米田史哉; 田中宗和; 畑玲央; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2024
      • 心外膜伝導を介するPeri-mitral atrial tachycardiaの解析
        田中宗和; 静田聡; 井上智之; 森永晃史; 米田史哉; 西脇修司; 畑玲央; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2024
      • 心房頻拍に対する2度目のカテーテルアブレーション後に,心房中隔穿刺孔を介した右→左シャントで低酸素血症が生じた1例
        井上智之; 西脇修司; 森永晃史; 米田史哉; 田中宗和; 畑玲央; 糀谷泰彦; 静田聡; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2024
      • Chemical ablationによるRoof領域lesionの慢性期での縮小が影響した心房頻拍の1例
        西脇修司; 井上智之; 森永晃史; 米田史哉; 田中宗和; 畑玲央; 糀谷泰彦; 静田聡; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2024
      • Expandable cryoballoonを用いた肺静脈隔離術における当院の成績
        米田史哉; 井上智之; 森永晃史; 田中宗和; 西脇修司; 畑玲央; 糀谷泰彦; 静田聡; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2024
      • Exploratory Identification and Stratification of Recurrence Risk after Cryoablation for Atrial Fibrillation Using Machine Learning Methods
        YONEDA Fumiya; KOHJITANI Hirohiko; NAKA Misaki; MORINAGA Akifumi; TANAKA Munekazu; NISHIWAKI Shushi; SHIZUTA Satoshi
        日本循環器学会学術集会(Web), 2023
      • Prediction of In-hospital Mortality in Patients with Acute Heart Failure by Using Machine Learning Methods
        TANAKA Munekazu; KOHJITANI Hirohiko; YAMAMOTO Erika; KATO Takao
        日本循環器学会学術集会(Web), 2023
      • DEVELOPMENT OF DEEP-NEURAL NETWORK BASED ARTIFICIAL INTELLIGENCE MODELS FOR IDENTIFICATION OF PULMONARY VEIN POTENTIALS FROM 12-LEADS ELECTROCARDIOGRAM OF PATIENTS WITH ATRIAL FIBRILLATION
        KOHJITANI Hirohiko; KOHJITANI Hirohiko; TANAKA Munekazu; NAKA Misaki; INOUE Tomoyuki; MORINAGA Akifumi; YONEDA Fumiya; NISHIWAKI Shushi; SHIZUTA Satoshi; OKUNO Yasushi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2023
      • A CASE OF REPEATED DELAYED SEVERE PERICARDIAL EFFUSION AFTER LEADLESS PACEMAKER IMPLANTATION FOR ADVANCED ATRIOVENTRICULAR BLOCK AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION
        YONEDA Fumiya; SHIZUTA Satoshi; NAKA Misaki; INOUE Tomoyuki; MORINAGA Akifumi; TANAKA Munekazu; NISHIWAKI Shushi; KOHJITANI Hirohiko; ONO Ko
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2023
      • THE ACCURACY DIFFERENCES IN DEVELOPING A DEEP NEURAL NETWORK TO IDENTIFY PULMONARY VEIN POTENTIALS DEPEND ON INPUT LEADS OF A 12-LEAD ELECTROCARDIOGRAM
        TANAKA Munekazu; KOHJITANI Hirohiko; KOHJITANI Hirohiko; YONEDA Fumiya; NISHIWAKI Shushi; OKUNO Yasushi; SHIZUTA Satoshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2023
      • Prediction of in-hospital mortality and worsening heart failure of patients with acute heart failure by using latest machine learning models
        TANAKA Munekazu; KATO Takao; KOHJITANI Hirohiko; YAMAMOTO Erika; KIMURA Takeshi
        日本心不全学会学術集会プログラム・抄録集, 2023
      • Metalloprotease Nardilysin regulates sinus node automaticity through modulating ion channel transcription.
        OHNO Mikiko; MATSUURA Hiroshi; MAKIYAMA Takeru; KOUJITANI Hirohiko; NISHI Kiyoto; NISHI Eiichiro
        日本薬理学会年会要旨集(Web), 2022
      • ミスセンス変異Lmna-S143Pを有するLMNA関連心筋症のラットモデル(Rat Model of LMNA-related Cardiomyopathy Carrying a Missense Mutation, Lmna-S143P)
        Huang Hai; Makiyama Takeru; Shirai Manabu; Wakabayashi Masaki; Ishikawa Taisuke; Nishiuchi Suguru; Moriuchi Kenji; Gao Jingshan; Kashiwa Asami; Imamura Tomohiko; Aizawa Takanori; Kohjitani Hirohiko; Kato Koichi; Ohno Seiko; Nakagawa Yasuaki; Yamaguchi Osamu; Kuwahara Koichiro; Makita Naomasa; Horie Minoru; Kimura Takeshi
        日本循環器学会学術集会抄録集, Mar. 2023
      • Histological Characteristics of a Rat Model of Cardiac Laminopathy Carrying Lmna p.S143P(タイトル和訳中)
        Huang Hai; Makiyama Takeru; Shirai Manabu; Wakabayashi Masaki; Yoshida Morikatsu; Nishiuchi Suguru; Moriuchi Kenji; Gao Jing Shan; Kashiwa Asami; Imamura Tomohiko; Aizawa Takanori; Kohjitani Hirohiko; Kato Koichi; Ohno Seiko; Nakagawa Yasuaki; Yamaguchi Osamu; Kuwahara Koichiro; Makita Naomasa; Horie Minoru; Kimura Takeshi; Ono Koh
        日本循環器学会学術集会抄録集, Mar. 2024
      • M16メタロエンドペプチダーゼによる心拍数制御機構
        大野美紀子; 松浦博; 西清人; 糀谷泰彦; 牧山武; 池田真也; 西英一郎
        日本循環薬理学会口演要旨集, 2024
      • Development of Deep-Generative Models with Fine-tuning Techniques for Genetic Risk Prediction and Prognosis Stratification of Hereditary Arrhythmic Disease
        三谷孟司; 糀谷泰彦; 糀谷泰彦; 岡本有司; 相澤卓範; 牧山武; 牧山武; 大野聖子; 堀江稔; 奥野恭史
        日本循環器学会学術集会(Web), 2024
      • 洞不全症候群に対してリードレスペースメーカ植込み後,VVI作動時にショックとなった1例
        西脇修司; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 静田聡; 尾野亘
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2024
      • VF zoneでICD頻回作動する頻拍を心内電位解析からTypical AVNRTと推定できた1例
        井上智之; 西脇修司; 森永晃史; 米田史哉; 田中宗和; 相澤卓範; 糀谷泰彦; 静田聡; 尾野亘
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2024
      • Attain Stability Quadリードを用いてCRT-Pへのupgradeに成功した左上大静脈遺残,右上大静脈欠損の1例
        西脇修司; 中美咲; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 静田聡
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2023
      • 当院におけるリードレスペースメーカ植込み100例の検討
        森永晃史; 米田史哉; 中美咲; 西脇修司; 田中宗和; 糀谷泰彦; 静田聡
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2023
      • 持続性心房細動に対するアブレーション中に大量の右左シャントによる低酸素血症で救命困難となった不整脈原性右室心筋症の1例
        井上智之; 喜多村恭平; 羽賀博典; 森永晃史; 米田史哉; 西脇修司; 田中宗和; 糀谷泰彦; 牧山武; 尾野亘; 静田聡
        日本心臓病学会学術集会(Web), 2023
      • 上大静脈をtriggerとし冠状静脈洞とマーシャル静脈の分岐部をsubstrateとするAFを心内心電図より明瞭に同定できた1例
        田中宗和; 静田聡; 井上智之; 森永晃史; 米田史哉; 西脇修司; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023
      • QDOT Micro電極とBi-polar電極の電位を比較することでOriginを推定し,大動脈左冠尖からの通電で同時に根治した2種類のLV summit PVCの1例
        西脇修司; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 静田聡; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023
      • 右房分界稜に著明なfractionated potentialsをみとめ,exit blockを伴う発火と頻拍中の拡張期電位をみとめた肺静脈隔離後の心房頻拍の1例
        井上智之; 静田聡; 森永晃史; 米田史哉; 西脇修司; 田中宗和; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023
      • QDOTのマイクロ電極に著明なdelayed potentialが記録された心尖部瘤を伴う肥大型心筋症の心室頻拍の1例
        米田史哉; 静田聡; 井上智之; 森永晃史; 田中宗和; 西脇修司; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023
      • QDOTカテーテルを用いたアブレーションのおけるContact Forceによる違いによる食道傷害の検討
        西脇修司; 静田聡; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 尾野亘
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023
      • 嚥下誘発性の一過性房室ブロックによる頻発性失神発作に対してCardioneuroablationを施行した1例
        米田史哉; 中美咲; 森永晃史; 田中宗和; 西脇修司; 糀谷泰彦; 静田聡
        日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2022
      • Metalloprotease Nardilysin Controls Heart Rate through the Transcriptional Regulation of Ion Channels Critical for Sinus Automaticity
        OHNO Mikiko; MATSUURA Hiroshi; MAKIYAMA Takeru; KOHJITANI Hirohiko; NISHI Kiyoto; IWASAKI Hirotaka; MATSUDA Shintaro; KIMURA Takeshi; NISHI Eiichiro
        日本循環器学会学術集会(Web), 2020
      • Mathematical Modeling and Analysis of Electrophysiological Characteristics of the Ventricular, Atrial, and Nodal-Like hiPSC-CMs
        KOHJITANI Hirohiko; KODA Shigeya; HIMRNO Yukiko; MAKIYAMA Takeru; HIROSE Sayako; WURIYANGHAI Yimin; HARITA Takeshi; HAYANO Mamoru; NISHIUCHI Suguru; YAMAMOTO Yuta; KIMURA Takeshi; NOMURA Akinori; AMANO Akira
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2017
      • The Relationship Between 3D Speckle-Tracking Echocardiography and High-Density Voltage Mapping in AF Patients
        TANAKA Munekazu; WATANABE Shin; YONEDA Fumiya; NISHIWAKI Shushi; KOHJITANI Hirohiko; SHIZUTA Satoshi; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Impact of Hemoglobin Level on Clinical Outcomes After Catheter Ablation in Patients with Atrial Fibrillation
        NISHIWAKI Shushi; KAWAJI Tetsuma; YOSHIZAWA Takashi; NISHIUCHI Suguru; YONEDA Fumiya; TANAKA Munekazu; KOMASA Akihiro; KOHJITANI Hirohiko; SHIZUTA Satoshi; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Development of Precise Genetic Prognostic Model for Hereditary Arrhythmia Disease Using Machine Learning
        KOHJITANI Hirohiko; KOHJITANI Hirohiko; MITANI Takeshi; OKAMOTO Yuji; AIZAWA Takanori; MAKIYAMA Takeru; MAKIYAMA Takeru; KASHIWA Asami; IMAMURA Tomohiko; OHNO Seiko; HORIE Minoru; SHIZUTA Satoshi; SHIZUTA Satoshi; KIMURA Takeshi; KIMURA Takeshi; OKUNO Yasushi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Arrhythmic Risk is NOT Homogeneous in C-Terminal KCNQ1 Variants of Long QT Syndrome
        KASHIWA Asami; MAKIYAMA Takeru; WADA Yuko; OZAWA Junichi; AIZAWA Takanori; IMAMURA Tomohiko; HUANG Hai; GAO Jingshan; KOHJITANI Hirohiko; OHNO Seiko; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Novel CPVT-Associated Calmodulin Mutation Activating RyR2 Channels Causes Robust Arrhythmogenicity in iPS Cell Model
        GAO Jingshan; MAKIYAMA Takeru; YAMAMOTO Yuta; KOBAYASHI Takuya; AOKI Hisaaki; MAURISSEN L Thomas; KASHIWA Asami; IMAMURA Tomohiko; AIZAWA Takanori; HUANG Hai; KOHJITANI Hirohiko; KATO Koichi; YOSHIDA Yoshinori; MAKITA Naomasa; WOLTJEN Knut; OHNO Seiko; KUREBAYASHI Nagomi; MURAYAMA Takashi; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Clinical Characteristics and Risk Stratification in Pediatric Brugada Syndrome
        IMAMURA Tomohiko; MAKIYAMA Takeru; OZAWA Junichi; HUANG Hai; AIZAWA Takanori; GAO Jingshan; KASHIWA Asami; KOHJITANI Hirohiko; KATO Koichi; AOKI Hisaaki; SUZUKI Hiroshi; SONODA Keiko; OHNO Seiko; SUMITOMO Naokata; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Exploratory Identification of Recurrence Risk After Cryoablation for Atrial Fibrillation Using Machine Learning Methods
        YONEDA Fumiya; KOHJITANI Hirohiko; TANAKA Munekazu; NISHIWAKI Shushi; KOMASA Akihiro; SHIZUTA Satoshi; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Late Sodium Current Inhibitor Shortens Prolonged Action Potential Durations in iPS Cell-derived Cardiomyocytes of long QT syndrome associated with Cav 1.2 Ion Selectivity Disruption
        KASHIWA Asami; MAKIYAMA Takeru; KOUJITANI Hirohiko; YAMAMOTO Yuta; YAMAMOTO Yuta; GAO Jingshan; HUANG Hai; IMAMURA Tomohiko; AIZAWA Takanori; ISHIKAWA Taisuke; ONO Seiko; TOYODA Futoshi; SATO Seiichi; TAKAHASHI Kazuhiro; HORIE Minoru; KIMURA Takeshi
        Journal of Physiological Sciences (Web), 2021
      • Incidence and Predictors of Iatrogenic Atrial Septal Defect (iASD) After Pulmonary Vein Isolation (PVI) by Transesophageal Echocardiogram (TEE)
        YOSHIZAWA Takashi; SHIZUTA Satoshi; TANAKA Munekazu; YAMAGAMI Shintaro; KOMASA Akihiro; KOHJITANI Hirohiko; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2021
      • Usefulness of Collaboration Between Mathematical Models and Cell Engineering for Elucidating Complex Disease Mechanisms and Discover Effective Drugs
        KOHJITANI Hirohiko; KASHIWA Asami; MAKIYAMA Takeru; ISHIKAWA Taisuke; TOYODA Futoshi; OHNO Seiko; HUANG Hai; GAO Jingshan; IMAMURA Tomohiko; AIZAWA Takanori; SHIZUTA Satoshi; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2021
      • Inhibition of Late Sodium Current Shortens Action Potential Durations in CACNA1C-E1115K iPS Cell Model with Disrupted Cav1.2 Ion Selectivity
        KASHIWA Asami; MAKIYAMA Takeru; KOHJITANI Hirohiko; MAURISSEN Thomas; WURIYANGHAI Yimin; YAMAMOTO Yuta; GAO Jingshan; HUANG Hai; IMAMURA Tomohiko; AIZAWA Takanori; ISHIKAWA Taisuke; OHNO Seiko; TOYODA Futoshi; SATO Seiich; TAKAHASHI Kazuhiro; WOLTJEN Knut; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2021
      • Antisense-Mediated Knockdown of CALM as a Therapeutic Strategy for Calmodulinopathy
        YAMAMOTO Yuta; MAKIYAMA Takeru; KONDO Yoshiki; IRIYAMA Yusuke; WURIYANGHAI Yimin; KOHJITANI Hirohiko; GAO Jingshan; KASHIWA Asami; HUANG Hai; AIZAWA Takanori; IMAMURA Tomohiko; ISHIKAWA Taisuke; YOSHIDA Yoshinori; OHNO Seiko; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2021
      • Modeling Inherited Arrhythmias Associated with Ryanodine Receptor Dysfunction Using iPS Cells
        MAKIYAMA Takeru; GAO Jingshan; YAMAMOTO Yuta; KASHIWA Asami; AIZAWA Takanori; IMAMURA Tomohiko; HUANG Hai; KOHJITANI Hirohiko; KATO Kouichi; ISHIKAWA Taisuke; AOKI Hisaaki; TOYODA Futoshi; WOLTEN Knut; YOSHIDA Yoshinori; OHNO Seiko; MAKITA Naomasa; KIMURA Takeshi
        日本循環器学会学術集会(Web), 2021
      • A High-Throughput Phenotype-Based Subtype Classification of Long-QT Syndrome Using Induced Pluripotent Stem Cell Model
        Daisuke Yoshinaga; Shiro Baba; Takeru Makiyama; Hirofumi Shibata; Takuya Hirata; Hirohiko Kohjitani; Yimin Wuriyanghai; Yuta Yamamoto; Bruce Conklin; Minoru Horie; Junko Takita; Toshio Heike
        CIRCULATION, Nov. 2019
      • Single Cell Electrophysiological Analysis of iPS Cell-Derived Cardiomyocytes Generated from Long-QT Syndrome Patients Carrying a CALM2 Mutation Using a Membrane Potential Imaging System
        YAMAMOTO Yuta; MAKIYAMA Takeru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; GAO Jingshan; KASHIWA Asami; HUANG Hai; ISHIKAWA Taisuke; OHNO Seiko; CHONABAYASHI Kazuhisa; SUDA Kenji; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019
      • Algorithmic Auto-Recreation System of hiPSC-CMs Simulation and Prediction of Drug Testing
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; HUANG Hai; GAO Jingshan; KASHIWA Asami; WURIYANGHAI Yimin; YOSHINAGA Daisuke; KIMURA Takeshi; AMANO Akira
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019
      • Impaired response of KCNQ1 channel to beta-adrenergic stimulation in human iPSC-derived cardiomyocytes carrying a CALM2-N98S mutation associated with long QT syndrome
        YAMAMOTO Yuta; MAKIYAMA Takeru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; GAO Jingshan; KASHIWA Asami; HAI Huang; AIZAWA Takanori; IMAMURA Tomohiko; ISHIKAWA Taisuke; MOTOMURA Hideki; YOSHIDA Yoshinori; OHNO Seiko; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        Journal of Arrhythmia (Web), 2019
      • Patients characteristics of idiopathic ventricular fibrillation carrying SCN5A mutations without Brugada or long QT syndrome
        AIZAWA Takanori; MAKIYAMA Takeru; HUANG Hai; IMAMURA Tomohiko; GAO JingShan; KASHIWA Asami; YIMIN Wuriyanghai; KOHJITANI Hirohiko; YAMAMOTO Yuta; OHNO Seiko; HORIE Minoru
        Journal of Arrhythmia (Web), 2019
      • Algorithmic auto-recreation system of hiPSC-CMs simulation and prediction of drug testing
        KOHJITANI Hirohiko; KOUDA Shigeya; MAKIYAMA Takeru; IMAMURA Tomohiko; AIZAWA Takanori; KASHIWA Asami; GAO JingShan; HUANG Hai; WURIYANGHAI Yimin; YAMAMOTO Yuta; SIZUTA Satoshi; KIMURA Takeshi; NOMA Akinori
        Journal of Arrhythmia (Web), 2019
      • Predictive Value of Pulmonary Venous Flow Assessed by Intracardiac Echocardiography on Recurrence of Atrial Fibrillation
        SASAKI Yasuhiro; KOBORI Atsushi; YOSHIZAWA Takashi; MURAI Ryosuke; HATANI Takeshi; KOUJITANI Hirohiko; TOYOTA Toshiaki; IDE Yuuya; KIM Kite; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka
        Circulation Journal, 2013
      • Impact of Catheter Ablation for Atrial Fibrillation in Patients with Reduced Left Ventricular Ejection Fraction
        NISHIWAKI Shushi; YONEDA Fumiya; TANAKA Munekazu; KOMASA Akihiro; KOHJITANI Hirohiko; KIMURA Takeshi; SHIZUTA Satoshi
        日本循環器学会学術集会(Web), Mar. 2022
      • Development of a Genetic Prognostic Model for Hereditary Arrhythmia Disease Using Machine Learning
        KOHJITANI Hirohiko; MITANI Takeshi; AIZAWA Takanori; MAKIYAMA Takeru; KASHIWA Asami; IMAMURA Tomohiko; OHNO Seiko; HORIE Minoru; SHIZUTA Satoshi; KIMURA Takeshi; OKUNO Yasushi
        日本循環器学会学術集会(Web), Mar. 2022
      • Haploinsufficient Variant of KCNH2 Cause Better Arrhythmia Outcome in Patients with Type 2 Long QT Syndrome
        AIZAWA Takanori; WADA Yuko; MAKIYAMA Takeru; HUANG Hai; IMAMURA Tomohiko; GAO Jingshan; KASHIWA Asami; KOHJITANI Hirohiko; KATO Koichi; OHNO Seiko; KIMURA Takeshi; HORIE Minoru
        日本循環器学会学術集会(Web), Mar. 2022
      • A Novel CPVT-associated Calmodulin Mutation Causes Ca2+ Leaks via RyR2 in iPSC Model Due to Increased Mutant CaM-RyR2 Binding Affinity
        GAO Jingshan; MAKIYAMA Takeru; YAMAMOTO Yuta; KASHIWA Asami; IMAMURA Tomohiko; AIZAWA Takanori; KOHJITANI Hirohiko; KATO Koichi; OHNO Seiko; HORIE Minoru; KIMURA Takeshi; AOKI Hisaaki; MAKITA Naomasa
        日本循環器学会学術集会(Web), Mar. 2022
      • Development of an Oligonucleotide-Based Therapeutic Approach for Calmodulinopathy
        MAKIYAMA Takeru; YAMAMOTO Yuta; KONDOH Yoshiki; GAO Jingshan; KASHIWA Asami; AIZAWA Takanori; IMAMURA Tomohiko; HUANG Hai; KOHJITANI Hirohiko; ISHIKAWA Taisuke; YOSHIDA Yoshinori; OHNO Seiko; MAKITA Naomasa; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2021
      • 遺伝性不整脈に対するオーダーメイド医療の現在の概観 iPS細胞を用いたリアノジン受容体遺伝子異常による遺伝性不整脈のモデリング(Current Perspective on Precision Medicine of Inherited Arrhythmias Modeling Inherited Arrhythmias Associated with Ryanodine Receptor Dysfunction Using iPS Cells)
        Makiyama Takeru; Gao Jingshan; Yamamoto Yuta; Kashiwa Asami; Aizawa Takanori; Imamura Tomohiko; Huang Hai; Kohjitani Hirohiko; Kato Kouichi; Ishikawa Taisuke; Aoki Hisaaki; Toyoda Futoshi; Wolten Knut; Yoshida Yoshinori; Ohno Seiko; Makita Naomasa; Kimura Takeshi
        日本循環器学会学術集会抄録集, Mar. 2021
      • Modeling RYR2-related Long-QT Syndrome Using iPS Cell Model Generated by CRISPR/Cas9-based Knock-in Genome Editing Technology
        GAO Jingshan; MAKIYAMA Takeru; OHNO Seiko; YAMAMOTO Yuta; KASHIWA Asami; IMAMURA Tomohiko; AIZAWA Takanori; HUANG Hai; KOHJITANI Hirohiko; KATO Koichi; TOYODA Futoshi; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2021
      • Sex Differences and Arrhythmia Recurrence after Catheter Ablation for Atrial Fibrillation in a Large Single-center Registry
        TANAKA Munekazu; SHIZUTA Satoshi; YONEDA Fumiya; NISHIWAKI Shushi; KOMASA Akihiro; YOSHIZAWA Takashi; KOHJITANI Hirohiko; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2021
      • QT延長症候群に関連するCALM2-N98S変異はヒトiPSC由来心筋細胞におけるβ-アドレナリン刺激に対するKCNQ1チャネルの応答を損なう(CALM2-N98S Mutation Associated with Long QT Syndrome Impaired the Response of KCNQ1 Channel to Beta-adrenergic Stimulation in Human iPSC-derived Cardiomyocytes)
        Yamamoto Yuta; Makiyama Takeru; Wuriyanghai Yimin; Kohjitani Hirohiko; Hirose Sayako; Gao Jingshan; Kashiwa Asami; Huang Hai; Aizawa Takanori; Imamura Tomohiko; Ishikawa Taisuke; Yoshida Yoshinori; Ohno Seiko; Horie Minoru; Makita Naomasa; Kimura Takeshi
        日本循環器学会学術集会抄録集, Jul. 2020
      • 人工知能による細胞特異的hiPSC-CMsのシミュレーションと薬物試験予測の最適化手法(Artificial Intelligence Based Optimization System for Cell-specific hiPSC-CMs Simulation and Prediction of Drug Testing)
        Kohjitani Hirohiko; Makiyama Takeru; Yamamoto Yuta; Yimin Wuriyanghai; Yoshinaga Daisuke; Kashiwa Asami; Imamura Tomohiko; Aizawa Takanori; Gao Jingshan; Huang Hai; Shizuta Satoshi; Kimura Takeshi
        日本循環器学会学術集会抄録集, Jul. 2020
      • Metalloprotease nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity.
        OHNO Mikiko; MATSUURA Hiroshi; MAKIYAMA Takeru; KOJITANI Hirohiko; NISHI Kiyoto; IWASAKI Hirotaka; MATSUDA Shintaro; KIMURA Takeshi; NISHI Eiichiro
        日本薬理学会年会要旨集(Web), Jul. 2020
      • LMNA-Related Cardiomyopathy Specific Induced-Pluripotent Stem Cells-derived Cardiomyocytes Stressed by Adrenergic Stimulation Recapitulate the Aging-Related Phenotype in an Early-Phase of Differentiation
        NISHIUCHI Suguru; MAKIYAMA Takeru; SASAKI Kenichi; KOHJITANI Hirohiko; YIMIN Wuriyanghai; YAMAMOTO Yuta; HARITA Takeshi; HAYANO Mamoru; KAMAKURA Tsukasa; OHNO Seiko; YOSHIDA Yoshinori; DOI Takahiro; SHIZUTA Satoshi; AIBA Takeshi; HORIE Minoru; KIMURA Takeshi
        Circulation Journal, Mar. 2015
      • The Prevalence of Subclinical Atrial Fibrillation and Anticoagulant Treatment in Patients with Cardiac Implantable Electronic Device
        YOSHIZAWA Takashi; KOBORI Atsushi; ITO Shinya; KASAMOTO Manabu; MURAI Ryosuke; KOHJITANI Hirohiko; HATANI Takeshi; KIM Kite; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka
        Circulation Journal, Mar. 2014
      • Requirement of Discontinuation of Amiodarone for Lethal Arrhythmias
        KOHJITANI Hirohiko; KOBORI Atsushi; SASAKI Yasuhiro; KIM Kitae; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka
        Journal of Arrhythmia, Jun. 2013
      • A case of successful endovascular treatment for infrarenal abdominal aortic stenosis
        YOSHIZAWA Takashi; EHARA Natuhiko; MURAI Ryosuke; HATANI Takeshi; KOHJITANI Hirohiko; SASAKI Yasuhiro; OKADA Taiji; TOYOTA Toshiaki; IDE Yuuya; KIM Kitae; KITAI Takeshi; KOBORI Atushi; KINOSHITA Makoto; KAJI Shuitiro; TANI Tomoko; HURUKAWA Yutaka
        日本心血管インターベンション治療学会誌, May 2013
      • Prevalence and Location of J-wave in Patients with Implantable Cardioverter Defibrillator
        KOHJITANI Hirohiko; KOBORI Atsushi; KIM Kite; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka; KITA Toru
        Circulation Journal, Mar. 2013
      • Posterior reversible encephalopathy syndrome (PRES) as a rare complication of coronary/aortic angiography: A case report
        KOHJITANI Hirohiko; EHARA Natsuhiko; KIM Kitae; KITAI Takeshi; KOBORI Atsushi; KINOSHITA Makoto; KAJI Shuichiro; YAMAMURO Atsushi; TANI Tomoko; FURUKAWA Yutaka
        日本心血管インターベンション治療学会誌, Jun. 2012
      • Characteristics of Lethal Arrhythmia Cases Switched from Intravenous to Internal Use of Amiodarone
        KOHJITANI Hirohiko; KOBORI Atsushi; KIM Kite; KITAI Takeshi; KINOSHITA Makoto; KAJI Shujiro; YAMAMURO Atsushi; TANI Tomoko; FURUKAWA Yutaka
        心電図, Sep. 2011
      • 小児におけるブルガダ症候群の臨床的側面 性別と年齢が予後に与える影響(Clinical Aspects of Brugada Syndrome in Children: The Impact of Gender and Age on the Prognosis)
        今村 知彦; 牧山 武; 小澤 淳一; 相澤 卓範; 柏 麻美; 糀谷 泰彦; 加藤 浩一; 青木 寿明; 鈴木 博; 園田 桂子; 大野 聖子; 住友 直方; 堀江 稔; 木村 剛
        日本循環器学会学術集会抄録集, Mar. 2022
      • Metalloprotease Nardilysin regulates sinus automaticity through transcriptional regulation of ion channels.
        OHNO Mikiko; NISHI Kiyoto; MATSUURA Hiroshi; MAKIYAMA Takeru; KOUJITANI Hirohiko; MATSUDA Shintaro; KIMURA Takeshi; NISHI Eiichiro
        日本薬理学会年会要旨集(Web), 2022
      • 個々のiPS細胞由来心筋細胞の多様な電気活動を再現する数理モデルを導くパラメータ最適化手法
        姫野友紀子; 糀谷泰彦; 豊田太; 張芸馨; 野間昭典; 天野晃
        心電学関連春季大会プログラム・抄録集(Web), 2021
      • 小児におけるブルガダ症候群の臨床的側面 性別と年齢が予後に与える影響(Clinical Aspects of Brugada Syndrome in Children: The Impact of Gender and Age on the Prognosis)
        今村 知彦; 牧山 武; 小澤 淳一; 相澤 卓範; 柏 麻美; 糀谷 泰彦; 加藤 浩一; 青木 寿明; 鈴木 博; 園田 桂子; 大野 聖子; 住友 直方; 堀江 稔; 木村 剛
        日本循環器学会学術集会抄録集, Mar. 2022
      • 植込み型除細動器電池交換後の薬剤抵抗性心室細動に対して,心房ペーシングが有効であった早期再分極症候群の1例
        西脇修司; 米田史哉; 田中宗和; 小正晃裕; 糀谷泰彦; 静田聡; 木村剛
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2022
      • 非心房細動高齢患者に対するリードレスペースメーカと経静脈リードペースメーカの比較
        米田史哉; 静田聡; 田中宗和; 西脇修司; 小正晃裕; 糀谷泰彦; 木村剛
        植込みデバイス関連冬季大会プログラム・抄録集(Web), 2022
      • Modeling inherited arrhythmias using human induced pluripotent stem cell-derived cardiomyocytes: Diagnostic tools, investigation of pathogenic mechanisms, development of new therapeutic approaches.
        牧山武; 牧山武; 山本雄大; 山本雄大; 吉永大介; 吉永大介; 廣瀬紗也子; 相澤卓範; 柏麻美; GAO Gingshan; 今村知彦; HUANG Hai; 糀谷泰彦; 糀谷泰彦; 大野聖子; 蒔田直昌; 堀江稔; 木村剛
        循環器内科, Oct. 2021
      • 日本人レジストリに登録された小児ブルガダ症候群の臨床的特徴(Clinical Characteristics of Pediatric Brugada Syndrome in Japanese Registry)
        今村 知彦; 牧山 武; 小澤 淳一; 相澤 卓範; 柏 麻美; 山本 雄大; 糀谷 泰彦; 加藤 浩一; 青木 寿明; 大野 聖子; 鈴木 博; 住友 直方; 吉永 正夫; 堀江 稔; 木村 剛
        日本循環器学会学術集会抄録集, Mar. 2021
      • PENTARAYを用いたPACの最早期MappingによるLA roof隔離が著効した心不全合併心房細動の1例
        小正晃裕; 静田聡; 米田史哉; 田中宗和; 西脇修司; 糀谷泰彦; 木村剛
        日本不整脈心電学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2021
      • AVNRTとJunctional tachycardia併存例で,Atrial overdrive pacingで両者を鑑別し,Cryoablationにて双方とも焼灼に成功した1症例
        米田史哉; 静田聡; 西脇修司; 田中宗和; 小正晃裕; 糀谷泰彦; 木村剛
        日本不整脈心電学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2021
      • Wide QRS tachycardiaを含む4種類のAVNRT・AVRTが誘発され,concealed NV/NF fiberの存在が疑われた,後中隔顕性WPW症候群の1例
        西脇修司; 米田史哉; 田中宗和; 小正晃裕; 糀谷泰彦; 静田聡; 木村剛
        日本不整脈心電学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2021
      • 心筋L型カルシウムチャネルのイオン選択性を阻害するCACNA1C-E1115KのヒトiPS細胞モデル(Human Induced Pluripotent Stem Cell Model of CACNA1C-E1115K which Impairs Ion Selectivity of the Cardiac L-type Calcium Channel)
        柏 麻美; 牧山 武; Maurissen Thomas; 糀谷 泰彦; Wuriyanghai Yimin; 山本 雄大; Gao Jingshan; Huang Hai; 今村 知彦; 相澤 卓範; 石川 泰輔; 大野 聖子; 豊田 太; 佐藤 誠一; 高橋 一浩; Woltjen Knut; 堀江 稔; 蒔田 直昌; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020
      • 複雑な疾患メカニズムの解明における数理モデルとiPS細胞を利用した細胞工学を組み合わせた技術の有用性(Usefulness of Combination of Mathematical Modeling and Cell Engineering Using Induced Pluripotent Stem Cells for Revealing Complex Disease Mechanism)
        糀谷 泰彦; 柏 麻美; 野間 昭典; 牧山 武; 豊田 太; 山本 雄大; 烏日揚海 伊敏; 堀江 稔; 大野 聖子; 高 景山; 黄 海; 今村 知彦; 相澤 卓範; 静田 聡; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020
      • 心筋細胞活動電位数理モデルを実験まく電位記録に合わせる自動パラメータ最適化
        野間昭典; 姫野友紀子; 糀谷泰彦; 豊田太; 幸田茂也; 天野晃
        日本生理学雑誌(Web), 2022
      • NRDC regulates sinus automaticity through transcriptional regulation of ionchannels
        大野美紀子; 松浦博; 牧山武; 糀谷泰彦; 西清人; 松田真太郎; 木村剛; 西英一郎
        日本循環薬理学会口演要旨集, 2021
      • CALM2-N98S Mutation Associated with Long QT Syndrome Impaired the Response of KCNQ1 Channel to Beta-adrenergic Stimulation in Human iPSC-derived Cardiomyocytes
        YAMAMOTO Yuta; MAKIYAMA Takeru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; GAO Jingshan; KASHIWA Asami; HUANG Hai; AIZAWA Takanori; IMAMURA Tomohiko; ISHIKAWA Taisuke; YOSHIDA Yoshinori; OHNO Seiko; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本循環器学会学術集会(Web), Jul. 2020
      • Artificial Intelligence Based Optimization System for Cell-specific hiPSC-CMs Simulation and Prediction of Drug Testing
        KOHJITANI Hirohiko; MAKIYAMA Takeru; YAMAMOTO Yuta; YIMIN Wuriyanghai; YOSHINAGA Daisuke; KASHIWA Asami; IMAMURA Tomohiko; AIZAWA Takanori; GAO Jingshan; HUANG Hai; SHIZUTA Satoshi; KIMURA Takeshi
        日本循環器学会学術集会(Web), Jul. 2020
      • Metalloprotease Nardilysin Controls Heart Rate through the Transcriptional Regulation of Ion Channels Critical for Sinus Automaticity(和訳中)
        Ohno Mikiko; Matsuura Hiroshi; Makiyama Takeru; Kohjitani Hirohiko; Nishi Kiyoto; Iwasaki Hirotaka; Matsuda Shintaro; Kimura Takeshi; Nishi Eiichiro
        日本循環器学会学術集会抄録集, Jul. 2020
      • Human Induced Pluripotent Stem Cell Model of CACNA1C-E1115K which Impairs Ion Selectivity of the Cardiac L-type Calcium Channel(和訳中)
        柏 麻美; 牧山 武; Maurissen Thomas; 糀谷 泰彦; Wuriyanghai Yimin; 山本 雄大; Gao Jingshan; Huang Hai; 今村 知彦; 相澤 卓範; 石川 泰輔; 大野 聖子; 豊田 太; 佐藤 誠一; 高橋 一浩; Woltjen Knut; 堀江 稔; 蒔田 直昌; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020
      • Usefulness of Combination of Mathematical Modeling and Cell Engineering Using Induced Pluripotent Stem Cells for Revealing Complex Disease Mechanism(和訳中)
        糀谷 泰彦; 柏 麻美; 野間 昭典; 牧山 武; 豊田 太; 山本 雄大; 烏日揚海 伊敏; 堀江 稔; 大野 聖子; 高 景山; 黄 海; 今村 知彦; 相澤 卓範; 静田 聡; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020
      • Multi-layer Cardiac Pacemaker Mechanisms demonstrated in Human Induced Pluripotent Stem Cells by Developing Mathematical Cell Models
        KOHJITANI Hirohiko; KODA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; YAMAMOTO Yuta; WURIYANGHAI Yimin; YOSHINAGA Daisuke; KASHIWA Asami; AMANO Akira; NOMA Akinori; KIMURA Takeshi
        Journal of Physiological Sciences (Web), Mar. 2020
      • CACNA1C-E1115K Mutation Associated with Overlap Phenotype of Long-QT and Brugada Syndrome Disrupts Cav 1.2 Ion Selectivity in Patient-specific iPS Cell-derived Cardiomyocytes
        KASHIWA Asami; MAKIYAMA Takeru; KOHJITANI Hirohiko; MAURISSEN Thomas; WURIYANGHAI Yimin; YAMAMOTO Yuta; GAO Jingshan; HUANG Hai; IMAMURA Tomohiko; AIZAWA Takanori; ISHIKAWA Taisuke; OHNO Seiko; TOYODA Futoshi; SATO Seiich; TAKAHASHI Kazuhiro; WOLTJEN Knut; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        Journal of Physiological Sciences (Web), Mar. 2020
      • Mechanisms of Pathophysiology Underlying Arrhythmia Analyzed by Computer Simulations
        HIMENO Yukiko; OKAMOTO Yosuke; KOJITANI Hirohiko; ONO Kyoichi; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences (Web), 2020
      • Morphological and Electrophysiological Characterization of Homozygous Lamin A/C Knockout Human Induced-Pluripotent Stem Cell-Derived Cardiomyocytes
        Yimin Wuriyanghai; Takeru Makiyama; Yuta Yamamoto; Hirohiko Kohjitani; Sayako Hirose; Jingshan Gao; Asami Kashiwa; Hai Huang; Takanori Aizawa; Tomohiko Imamura; Seiko Ohno; Minoru Horie; Takeshi Kimura
        CIRCULATION, Nov. 2019
      • KCNQ1 Channel Dysfunction in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying a CALM2-N98S Mutation Associated With Long QT Syndrome
        Yuta Yamamoto; Takeru M. Makiyama; Yimin Wuriyanghai; Hirohiko Kohjitani; Sayako Hirose; Jingshan Gao; Asami Kashiwa; Huang Hai; Takanori Aizawa; Tomohiko Imamura; Taisuke Ishikawa; Seiko Ohno; Kazuhisa Chonabayashi; Hideki Motomura; Yoshinori Yoshida; Minoru Horie; Naomasa Makita; Takeshi Kimura
        CIRCULATION, Nov. 2019
      • Overlapping Sick Sinus Syndrome Associated with SCN5A Mutations in Patients with Brugada Syndrome
        KASHIWA Asami; MAKIYAMA Takeru; OHNO Seiko; YAMAMOTO Yuta; KOHJITANI Hirohiko; GAO Jingshan; KATO Koichi; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2019
      • Three-dimensional Structural Analysis of Mutant Ryanodine Receptor Type 2 Channels Associated with Catecholaminergic Polymorphic Ventricular Tachycardia
        GAO Jingshan; MAKIYAMA Takeru; OHNO Seiko; YAMAMOTO Yuta; WURIYANGHAI Yimin; KOHJITANI Hirohiko; KASHIWA Asami; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2019
      • hiPSC-CMシミュレーションのアルゴリズム的自動再生システムと薬剤検査の予測(Algorithmic Auto-recreation System of hiPSC-CMs Simulation and Prediction of Drug Testing)
        糀谷 泰彦
        日本循環器学会学術集会抄録集, Mar. 2019
      • Modeling Overlapping Phenotypes of Long-QT and Brugada Syndrome with CACNA1C-E1115K that Alters Ion Selectivity of the Cardiac L-Type Calcium Channel Using Induced Pluripotent Stem Cells
        KASHIWA Asami; MAKIYAMA Takeru; KOHJITANI Hirohiko; WURIYANGHAI Yimin; YAMAMOTO Yuta; GAO Jingshan; HUANG Hai; ISHIKAWA Taisuke; OHNO Seiko; TOYODA Futoshi; SATO Seiichi; HORIE Minoru; MAKIYA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019
      • Structural Insights into Catecholaminergic Polymorphic Ventricular Tachycardia-Associated RyR2 Mutant Channels Using a Three-Dimensional In Silico Model
        GAO Jingshan; MAKIYAMA Takeru; OHNO Seiko; YAMAMOTO Yuta; WURIYANGHAI Yimin; KOHJITANI Hirohiko; KASHIWA Asami; HAI Huang; KATOU Kouichi; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019
      • 経皮的ASD閉鎖術の術前・術後に経皮的カテーテル心筋焼灼術を施行した1例
        糀谷泰彦; 静田聡; 中井久登; 田中宗和; 山上新太郎; 相澤卓範; 小正晃裕; 吉澤尚志; 牧山武; 木村剛
        日本不整脈心電学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2019
      • Nardilysin controls heart rate through the transcriptional regulation of ion channels critical for sinus automaticity.
        Ohno Mikiko; Matsuura Hiroshi; Makiyama Takeru; Koujitani Yasuhiko; Nishi Kiyoto; Iwasaki Hirotaka; Matsuda Shintaro; Kimura Takeshi; Nishi Eiichiro
        Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2019
      • ヒトiPS由来分化心筋の数理モデルを用いた細胞特異的な活動電位波形の再現とIKr電流遮断シミュレーションによる反応性の検討
        糀谷泰彦; 幸田茂也; 姫野友紀子; 牧山武; 木村剛; 野間昭典; 天野晃
        心電図, 2019
      • Propranolol Attenuates Late Sodium Current in Patient-specific Stem Cell Model of Long-QT Syndrome Type 3
        HIROSE Sayako; MAKIYAMA Takeru; MELGARI Dario; WU Jie; YOKOI Fumika; WURIYANGHAI Yimin; YAMAMOTO Yuta; KOHJITANI Hirohiko; NISHIUCHI Suguru; HARITA Takeshi; HAYANO Mamoru; YOSHIMOTO Jun; OHNO Seiko; YOSHIDA Yoshinori; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2018
      • Development of Homozygous LaminA/C Deficient Human Induced Pluripotent Stem Cell Model for Analyzing the Pathophysiological Mechanism of Lamin A/C-related Cardiomyopathy
        WURIYANGHAI Yimin; MAKIYAMA Takeru; NISHIUCHI Suguru; YAMAMOTO Yuta; HIROSE Sayako; HAYANO Mamoru; HARITA Takeshi; KOHJITANI Hirohiko; YOKOI Fumika; CHONABAYASHI Kazuhisa; YOSHIDA Yoshinori; OHNO Seiko; HORIE Minoru; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2018
      • hiPSC-CMの細胞特異的で精密な数学的モデリングによりIKr遮断試験における二つの正反対のAPD反応が明らかになった(Cell-Specific Precise Mathematical Modeling of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test)
        Kohjitani Hirohiko; Koda Shigeya; Himeno Yukiko; Makiyama Takeru; Yokoi Fumika; Hirose Sayako; Wuriyanghai Yimin; Yamamoto Yuta; Horie Minoru; Kimura Takeshi; Noma Akinori; Amano Akira
        日本循環器学会学術集会抄録集, Mar. 2018
      • The Inactivation of L-type Ca2+ Cannel was Impaired in Human iPS Cell Model of Long-QT Syndrome with CALM2-D134H Mutation.
        YAMAMOTO Yuta; MAKIYAMA Takeru; HARITA Takeshi; HAYANO Mamoru; NISHIUCHI Suguru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; YOKOI Fumika; ISHIKAWA Taisuke; OHNO Seiko; CHONABAYASHI Kazuhisa; SUDA Kenji; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本循環器学会学術集会(Web), Mar. 2018
      • Cell-specific Precise Mathematical Modeling of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test
        KOHJITANI Hirohiko; KODA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences, Mar. 2018
      • Ionic mechanisms in the electrical activity of hiPS-CMs analyzed by developing a mathematical model
        KODA Shigeya; KOHJITANI Hirohiko; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences, Mar. 2018
      • CALM2関連性QT延長症候群iPSCモデルにおいて、l-cis-diltiazemは遅延したL型calciumチャネルの不活性化をさらに強める(l-cis-Diltiazem Enhances Slowed L-type Calcium Channel Inactivation in CALM2-associated Long-QT Syndrome iPSC Model)
        横井 文香; 牧山 武; 山本 雄大; 張田 健志; Wuriyanghai Yimin; 早野 護; 西内 英; 糀谷 泰彦; 廣瀬 紗也子; 高 景山; 大野 聖子; 豊田 太; 吉田 善紀; 蒔田 直昌; 堀江 稔; 木村 剛
        日本循環器学会学術集会抄録集, Mar. 2018
      • SCN5A-D1275N関連性心筋ナトリウムチャネロパチーのヒトiPSC由来心筋細胞モデルから、蛋白質分解の亢進によってナトリウム電流が低下することが判明した(Human iPSC-Derived Myocyte Model of SCN5A-D1275N-Related Cardiac Sodium Channelopathy Reveals Diminished Sodium Currents Resulting from Enhanced Protein Degradation)
        早野 護; 牧山 武; 鎌倉 令; 渡部 裕; 伊敏 烏日揚海; 西内 英; 張田 健志; 山本 雄大; 糀谷 泰彦; 廣瀬 紗也子; 横井 文香; 大野 聖子; 豊田 太; 吉田 善紀; 堀江 稔
        日本循環器学会学術集会抄録集, Mar. 2018
      • CALM2関連性QT延長症候群iPSCモデルにおいて、l-cis-diltiazemは遅延したL型calciumチャネルの不活性化をさらに強める(l-cis-Diltiazem Enhances Slowed L-type Calcium Channel Inactivation in CALM2-associated Long-QT Syndrome iPSC Model)
        横井 文香; 牧山 武; 山本 雄大; 張田 健志; Wuriyanghai Yimin; 早野 護; 西内 英; 糀谷 泰彦; 廣瀬 紗也子; 高 景山; 大野 聖子; 豊田 太; 吉田 善紀; 蒔田 直昌; 堀江 稔; 木村 剛
        日本循環器学会学術集会抄録集, Mar. 2018
      • Cell-specific Precise Computer Simulation of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; YOKOI Fumika; HIROSE Sayako; WURIYANGHAI Yimin; YAMAMOTO Yuta; HORIE Minoru; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2018
      • Novel Mathematical Models of All Subtypes of Induced Pluripotent Stem Cell Derived Cardiomyocytes
        Hirohiko Kohjitani; Shigeya Koda; Yukiko Himeno; Takeru Makiyama; Fumika Yokoi; Sayako Hirose; Yimin Wuriyanghai; Yuta Yamamoto; Minoru Horie; Takeshi Kimura; Akinori Noma; Akira Amano
        CIRCULATION, Nov. 2017
      • Propranolol Inhibits Late Sodium Current in Long-QT Syndrome Type 3 Human Induced Pluripotent Stem Cell-drived Myocyte Model
        Sayako Hirose; Takeru Makiyama; Dario Melgari; Jie Wu; Fumika Yokoi; Yimin Wuriyanghai; Yuta Yamamoto; Hirohiko Kohjitani; Suguru Nishiuchi; Takeshi Harita; Mamoru Hayano; Jun Yoshimoto; Seiko Ohno; Yoshinori Yoshida; Minoru Horie; Takeshi Kimura
        CIRCULATION, Nov. 2017
      • Establishment of Homozygous LMNA Knockout Human Induced Pluripotent Stem Cells for Analyzing Disease-Causing Mechanism of Laminopathies
        Yimin Wuriyanghai; Takeru Makiyama; Mamoru Hayano; Sayako Hirose; Suguru Nishiuchi; Yuta Yamamoto; Takeshi Harita; Hirohiko Kohjitani; Yokoi Fumika; Yoshinori Yoshida; Seiko Ohno; Takeshi Kimura; Minoru Horie
        CIRCULATION, Nov. 2017
      • Human iPSC-Derived Myocyte Mmodel of SCN5A-D1275N-Related Cardiac Sodium Channelopathy Reveals Diminished Sodium Currents Resulting From Enhanced Protein Degradation
        Mamoru Hayano; Takeru Makiyama; Tsukasa Kamakura; Hiroshi Watanabe; Kenichi Sasaki; Shunsuke Funakoshi; Yimin Wuriyanghai; Suguru Nishiuchi; Takeshi Harita; Yuta Yamamoto; Hirohiko Kohjitani; Sayako Hirose; Fumika Yokoi; Jiarong Chen; Osamu Baba; Takahiro Horie; Kazuhisa Chonabayashi; Seiko Ohno; Futoshi Toyoda; Yoshinori Yoshida; Koh Ono; Minoru Horie; Takeshi Kimura
        CIRCULATION, Nov. 2017
      • Mathematical modeling and analysis of electrophysiological characteristics of the ventricular, atrial, and nodal-like hiPSC-CMs
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; YAMAMOTO Natsuki; MAKIYAMA Takeru; HARITA Takeshi; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences, Mar. 2017
      • L型Ca2+チャネル遺伝子変異によるQT延長症候群iPS細胞モデルにおいて、l-cis-DiltiazemはCaチャネル不活性化を改善した(l-cis-diltiazem rescues impaired calcium channel inactivation in an iPSC-model of CACNA1Cassociated long-QT syndrome)
        Harita Takeshi; Makiyama Takeru; Toyoda Futoshi; Sasaki Kenichi; Nishiuchi Suguru; Hayano Mamoru; Yamamoto Yuta; Kohjitani Hirohiko; Wuriyanghai Yimin; Hirose Sayako; Chen Jiarong; Fukuyama Megumi; Chonabayashi Kazuhisa; Ohno Seiko; Yoshida Yoshinori; Ueyama Takeshi; Shimizu Akihiko; Matsuura Hiroshi; Horie Minoru; Kimura Takeshi
        The Journal of Physiological Sciences, Mar. 2017
      • I-cis-diltiazem rescues impaired calcium channel inactivation in an iPSC-model of CACNA1C-associated long-QT syndrome
        HARITA Takeshi; MAKIYAMA Takeru; TOYODA Futoshi; SASAKI Kenichi; NISHIUCHI Suguru; HAYANO Mamoru; YAMAMOTO Yuta; KOHJITANI Hirohiko; WURIYANGHAI Yimin; HIROSE Sayako; CHEN Jiarong; FUKUYAMA Megumi; CHONABAYASHI Kazuhisa; OHNO Seiko; YOSHIDA Yoshinori; UEYAMA Takeshi; SHIMIZU Akihiko; MATSUURA Hiroshi; HORIE Minoru; KIMURA Takeshi
        Journal of Physiological Sciences, 2017
      • Modelling Long-QT Syndrome Type 3 Associated with Near-Miss Sudden Infant Death Syndrome Using Human-Induced Pluripotent Stem Cells
        HIROSE Sayako; MAKIYAMA Takeru; MELGARI Dario; WU Jie; WU Jie; YOKOI Fumika; WURIYANGHAI Yimin; KOHJITANI Hirohiko; YAMAMOTO Yuta; NISHIUCHI Suguru; HAYANO Mamoru; HARITA Takeshi; YOSHIMOTO Jun; OHNO Seiko; YOSHIDA Yoshinori; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2017
      • lL-cis-Diltiazem Ameliorates Impaired Calcium Channel Inactivation in a Patient-Specific Stem Cell Model of Long-QT Syndrome with a Calmodulin Mutation
        YOKOI Fumika; MAKIYAMA Takeru; HARITA Takeshi; YAMAMOTO Yuta; HAYANO Mamoru; NISHIUCHI Suguru; KOHJITANI Hirohiko; WURIYANGHAI Yimin; WURIYANGHAI Yimin; HIROSE Sayako; TOYODA Futoshi; YOSHIDA Yoshinori; MAKITA Naomasa; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2017
      • CALM2-D134H Mutation Associated with Long-QT Syndrome Prevents Inactivation of L-type Ca2+ Currents in Human iPS Cell Derived Cardiomyocytes.
        YAMAMOTO Yuta; MAKIYAMA Takeru; HARITA Takeshi; HAYANO Mamoru; NISHIUCHI Suguru; WURIYANGHAI Yimin; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; YOKOI Fumika; ISHIKAWA Taisuke; OHNO Seiko; CHINABAYASHI Kazuhisa; SUDA Kenji; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2017
      • Basic Cardiovascular Science Best Abstract Award: Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome With a CALM2 Mutation
        Yuta Yamamoto; Takeru Makiyama; Takeshi Harita; Kenichi Sasaki; Mamoru Hayano; Suguru Nishiuchi; Yimin Wuriyanghai; Hirohiko Kohjitani; Sayako Hirose; Jiarong Chen; Taisuke Ishikawa; Hideki Motomura; Seiko Ohno; Kazuhisa Chonabayashi; Yoshinori Yoshida; Minoru Horie; Naomasa Makita; Takeshi Kimura
        CIRCULATION, Nov. 2016
      • Basic Cardiovascular Science Best Abstract Award: Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome With a CALM2 Mutation
        Yuta Yamamoto; Takeru Makiyama; Takeshi Harita; Kenichi Sasaki; Mamoru Hayano; Suguru Nishiuchi; Yimin Wuriyanghai; Hirohiko Kohjitani; Sayako Hirose; Jiarong Chen; Taisuke Ishikawa; Hideki Motomura; Seiko Ohno; Kazuhisa Chonabayashi; Yoshinori Yoshida; Minoru Horie; Naomasa Makita; Takeshi Kimura
        CIRCULATION, Nov. 2016
      • Abnormal Expressions of Cardiac Ion Channels-associated Genes in Lamin A/C-related Cardiomyopathy-specific Induced Pluripotent Stem Cell-derived Cardiomyocytes
        NISHIUCHI Suguru; MAKIYAMA Takeru; SASAKI Kenichi; YIMIN Wuriyanghai; KOHJITANI Hirohiko; HIROSE Sayako; YAMAMOTO Yuta; HARITA Takeshi; HAYANO Mamoru; OHNO Seiko; SHIZUTA Satoshi; YOSHIDA Yoshinori; HORIE Minoru; KIMURA Takeshi
        Circulation Journal, Mar. 2016
      • Electrophysiological Features of Patient-specific Human-induced Pluripotent Stem Cell-derived Cardiomyocytes Carrying the SCN5A-D1275N Mutation
        HAYANO Mamoru; MAKIYAMA Takeru; SASAKI Kenichi; KAMAKURA Tsukasa; WURIYANGHAI Yimin; CHEN Jiarong; NISHIUCHI Suguru; HARITA Takeshi; YAMAMOTO Yuta; KOHJITANI Hirohiko; HIROSE Sayako; OHNO Seiko; TOYODA Futoshi; WATANABE Hiroshi; YOSHIDA Yoshinori; HORIE Minoru; KIMURA Takeshi
        Circulation Journal, Mar. 2016
      • The Phenotype in Cardiomyocytes Derived from Induced Pluripotent Stem Cells of Long QT Syndrome Type 8 Patients without Extracardiac Phenotypes
        HARITA Takeshi; MAKIYAMA Takeru; SASAKI Kenichi; NISHIUCHI Suguru; HAYANO Mamoru; YAMAMOTO Yuta; KOHJITANI Hirohiko; HIROSE Sayako; JIARONG Chen; WURIYANGHAI Yimin; FUKUYAMA Megumi; TOYODA Futoshi; OHNO Seiko; YOSHIDA Yoshinori; UEYAMA Takeshi; SHIMIZU Akihiko; HORIE Minoru; KIMURA Takeshi
        Circulation Journal, 2016
      • Electrophysiological Features of Patient-specific Human-induced Pluripotent Stem Cell-derived Cardiomyocytes Carrying the SCN5A-D1275N Mutation
        HAYANO Mamoru; MAKIYAMA Takeru; SASAKI Kenichi; KAMAKURA Tsukasa; WURIYANGHAI Yimin; NISHIUCHI Suguru; HARITA Takeshi; YAMAMOTO Yuta; KOHJITANI Hirohiko; HIROSE Sayoko; OHNO Seiko; YOYODA Futoshi; WATANABE Hirohi; YOSHIDA Yoshinori; YAMANAKA Shinya; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016
      • Patient-Specific Induced Pluripotent Stem-Cell Models for Long QT Syndrome with the Missense Mutation in the KCNH2 Gene
        KOHJITANI Hirohiko; MAKIYAMA Takeru; SASAKI Kenichi; HIROSE Sayako; NISHIUCHI Suguru; HAYANO Mamoru; HARITA Takeshi; YAMAMOTO Yuta; WURIYANGHAI Yimin; OHNO Seiko; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016
      • l-cis Diltiazem Rescues Impaired Calcium Channel Inactivation in a Patient-specific Stem Cell Model of Long QT Syndrome with a CACNA1C Mutation
        HARITA Takeshi; MAKIYAMA Takeru; TOYODA Futoshi; SASAKI Kenichi; NISHIUCHI Suguru; HAYANO Mamoru; YAMAMOTO Yuta; KOHJITANI Hirohiko; WURIYANGHAI Yimin; HIROSE Sayako; CHEN Jiarong; CHONABAYASHI Kazuhisa; OHNO Seiko; YOSHIDA Yoshinori; UEYAMA Takeshi; SHIMIZU Akihiko; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016
      • Modeling of Long-QT Syndrome Associated with a Calmodulin Mutation Using Human Induced Pluripotent Stem Cells
        YAMAMOTO Yuta; MAKIYAMA Takeru; HARITA Takeshi; SASAKI Kenichi; HAYANO Mamoru; NISHIUCHI Suguru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; CHEN Jiarong; ISHIKAWA Taisuke; OHNO Seiko; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016
      • CALM遺伝子変異によるQT延長症候群の患者由来iPS細胞を用いた疾患モデルにおける変異アレル特異的ノックアウトによる治療的アプローチ
        山本雄大; 牧山武; 張田健志; 佐々木健一; 早野護; 西内英; ウリヤンハイ イミン; 糀谷泰彦; 廣瀬紗也子; チン カヨウ; 石川泰輔; 大野聖子; 蝶名林和久; 吉田善紀; 堀江稔; 蒔田直昌; 木村剛
        日本分子生物学会年会プログラム・要旨集(Web), 2016
      • Electrophysiological Properties of L-type Calcium Channels in Human Induced Pluripotent Stem Cells-Derived Cardiomyocytes
        HARITA Takeshi; MAKIYAMA Takeru; SASAKI Kenichi; HAYANO Mamoru; NISHIUCHI Suguru; YAMAMOTO Yuta; KOHJITANI Hirohiko; CHEN Jiarong; WURIYANGHAI Yimin; OHNO Seiko; ITO Hideki; YOSHIDA Yoshinori; HORIE Minoru; KIMURA Takeshi
        Circulation Journal, 2015
      • Genetic Backgrounds of Patients with Clinically Diagnosed Idiopathic Ventricular Fibrillation
        KOHJITANI Hirohiko; MAKIYAMA Takeru; SASAKI Kenichi; OHNO Seiko; WURIYANGHAI Yimin; HAYANO Mamoru; NISHIUCHI Suguru; YAMAMOTO Yuta; HARITA Takeshi; KIMURA Takeshi; HORIE Minoru
        Circulation Journal, 2015
      • Impact of J-wave in Patients With Structural Heart Disease
        Hirohiko Kohjitani; Atsushi Kobori; Yasuhiro Sasaki; Kitae Kim; Takeshi Kita; Natsuhiko Ehara; Makoto Kinoshita; Shuichiro Kaji; Tomoko Tani; Toru Kita; Yutaka Furukawa
        CIRCULATION, Nov. 2013
      • 脳梗塞にて発症した左室内血栓に対して抗凝固療法を行った一例
        吉澤尚志; 北井豪; 村井亮介; 糀谷泰彦; 羽渓健; 井手裕也; 豊田俊彬; 佐々木康博; 岡田大司; 金基泰; 小堀敦志; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕
        日本循環器学会近畿地方会(Web), 2013
      • 健診で発見された巨大冠動脈瘤の一例
        吉澤尚志; 江原夏彦; 村井亮介; 糀谷泰彦; 羽渓健; 佐々木康博; 金基泰; 北井豪; 小堀敦志; 木下慎; 加地修一郎; 谷知子; 古川裕; 中村健; 小山忠明
        日本循環器学会近畿地方会(Web), 2013
      • ICD記録により心室頻拍の誘発様式が判明し,心房細動アブレーションが奏効した1例
        糀谷泰彦; 小堀敦志; 村井亮介; 吉澤尚志; 羽渓健; 井手裕也; 豊田俊彬; 佐々木康博; 金基泰; 北井豪; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕; 北徹
        日本循環器学会近畿地方会(Web), 2013
      • 自己弁温存大動脈基部置換術後にAortic curtain dissectionを来したMarfan症候群の1例
        豊田俊彬; 北井豪; 村井亮介; 吉澤尚志; 糀谷泰彦; 羽渓健; 井手裕也; 佐々木康博; 金基泰; 小堀敦志; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 北徹; 古川裕
        日本循環器学会近畿地方会(Web), 2013
      • 心房細動へのアブレーション直後に認めた徐脈頻脈症候群に対してステロイド投与が著効した1例
        佐々木康博; 小堀敦志; 糀谷泰彦; 古川裕
        日本不整脈学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2013
      • 単純CTを用いたSound Mergeガイドにて心房細動アブレーションを施行した1例
        吉澤尚志; 小堀敦志; 伊藤慎八; 笠本学; 村井亮介; 糀谷泰彦; 羽溪健; 佐々木康博; 金基泰; 北井豪; 江原夏彦; 木下愼; 加地修一郎; 谷知子; 古川裕
        日本不整脈学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2013
      • 78歳まで根治術なしに生存し得たファロー四徴症の1例
        糀谷泰彦; 山室淳; 金基泰; 羽渓健; 北井豪; 小堀敦志; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕
        日本循環器学会近畿地方会(Web), 2012
      • 肺動脈弁狭窄症術後にwide QRS頻拍を呈し治療に難渋した1例
        羽渓健; 小堀敦志; 村井亮介; 吉澤尚志; 糀谷泰彦; 井手裕也; 岡田大司; 佐々木康博; 豊田俊彬; 金基泰; 北井豪; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕
        日本循環器学会近畿地方会(Web), 2012
      • 致死性不整脈に対するアミオダロン静注から内服への切り替え状況の検討
        糀谷泰彦; 小堀敦志; 羽渓健; 豊田俊彬; 井手裕也; 本田怜史; 西野共達; KIM K.; 北井豪; 江原夏彦; 木下愼; 加地修一郎; 山室淳; 谷知子; 古川裕
        Progress in Medicine, 2012
      • 急性膵炎として加療されていた劇症1型糖尿病の1例
        糀谷泰彦; 本庶祥子; 森可南子; 浜本芳之; 河崎祐貴子; 和田良春; 越山裕行
        糖尿病, 2011
      • Characteristics of Lethal Arrhythmia Cases Switched from Intravenous to Internal Use of Amiodarone
        Hirohiko Kohjitani; Atsushi Kobori; Kite Kim; Takeshi Kitai; Makoto Kinoshita; Shujiro Kaji; Atsushi Yamamuro; Tomoko Tani; Yutaka Furukawa
        journal of arrhythmia, 2011, Peer-reviewed
      • 脳原発hemangiopericytomaの肝転移に対して肝拡大右葉切除術を施行した一例
        糀谷泰彦; 多田正晴; 寺嶋宏明; 中西保貴; 吉村弥緒; 高橋英雄; 吉田昌弘; 吉冨摩美; 上田修吾; 橋田裕毅; 尾崎信弘
        日本肝胆膵外科学会・学術集会プログラム・抄録集, 2010

      Presentations

      • Overview and Prospects for AI Research and Social Implementation in the Field of Cardiovascular Disease, with a Focus on Deep Learning
        Hirohiko Kohjitani
        The 16th Annual KCGH Forum, 14 Dec. 2024, Invited
      • Current Status and Prospects for AI Research and Social Implementation in the Field of Cardiovascular Disease, with a Focus on Deep Learning
        Hirohiko Kohjitani
        KYOTO Cardiovascular Meeting, 13 Dec. 2024, Invited
      • In-silico systems for iPS cell-derived cardiomyocytes: needs and potential
        Hirohiko Kohjitain
        BioMecForum21, 07 Dec. 2024, Invited
      • Post-discharge Use of Tolvaptan in Patients with Heart Failure as a Predictor of 2-year Rehospitalization: Explainable Artificial-Intelligence Based Study
        糀谷泰彦; 山本絵里香; 内野詠一郎; 田中宗和; 瀬尾拓哉; 仲山加奈子; 高野橋健太; 尾野亘; 奥野恭史; 奥野恭史
        日本循環器学会学術集会(Web), 2024
      • Development of a Genetic Prognostic Model for Hereditary Arrhythmia Disease Using Machine Learning
        KOHJITANI Hirohiko; MITANI Takeshi; AIZAWA Takanori; MAKIYAMA Takeru; KASHIWA Asami; IMAMURA Tomohiko; OHNO Seiko; HORIE Minoru; SHIZUTA Satoshi; KIMURA Takeshi; OKUNO Yasushi
        日本循環器学会学術集会(Web), Mar. 2022, (一社)日本循環器学会
      • Development of Precise Genetic Prognostic Model for Hereditary Arrhythmia Disease Using Machine Learning
        KOHJITANI Hirohiko; KOHJITANI Hirohiko; MITANI Takeshi; OKAMOTO Yuji; AIZAWA Takanori; MAKIYAMA Takeru; MAKIYAMA Takeru; KASHIWA Asami; IMAMURA Tomohiko; OHNO Seiko; HORIE Minoru; SHIZUTA Satoshi; SHIZUTA Satoshi; KIMURA Takeshi; KIMURA Takeshi; OKUNO Yasushi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2022
      • Usefulness of Collaboration Between Mathematical Models and Cell Engineering for Elucidating Complex Disease Mechanisms and Discover Effective Drugs
        KOHJITANI Hirohiko; KASHIWA Asami; MAKIYAMA Takeru; ISHIKAWA Taisuke; TOYODA Futoshi; OHNO Seiko; HUANG Hai; GAO Jingshan; IMAMURA Tomohiko; AIZAWA Takanori; SHIZUTA Satoshi; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2021
      • Artificial Intelligence Based Optimization System for Cell-specific hiPSC-CMs Simulation and Prediction of Drug Testing
        KOHJITANI Hirohiko; MAKIYAMA Takeru; YAMAMOTO Yuta; YIMIN Wuriyanghai; YOSHINAGA Daisuke; KASHIWA Asami; IMAMURA Tomohiko; AIZAWA Takanori; GAO Jingshan; HUANG Hai; SHIZUTA Satoshi; KIMURA Takeshi
        日本循環器学会学術集会(Web), Jul. 2020, (一社)日本循環器学会
      • Algorithmic auto-recreation system of hiPSC-CMs simulation and prediction of drug testing
        KOHJITANI Hirohiko; KOUDA Shigeya; MAKIYAMA Takeru; IMAMURA Tomohiko; AIZAWA Takanori; KASHIWA Asami; GAO JingShan; HUANG Hai; WURIYANGHAI Yimin; YAMAMOTO Yuta; SIZUTA Satoshi; KIMURA Takeshi; NOMA Akinori
        Journal of Arrhythmia (Web), 2019
      • Algorithmic Auto-Recreation System of hiPSC-CMs Simulation and Prediction of Drug Testing
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; HUANG Hai; GAO Jingshan; KASHIWA Asami; WURIYANGHAI Yimin; YOSHINAGA Daisuke; KIMURA Takeshi; AMANO Akira
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019
      • Cell-specific Precise Mathematical Modeling of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test
        KOHJITANI Hirohiko; KODA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences, Mar. 2018, (一社)日本生理学会
      • Mathematical modeling and analysis of electrophysiological characteristics of the ventricular, atrial, and nodal-like hiPSC-CMs
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; YAMAMOTO Natsuki; MAKIYAMA Takeru; HARITA Takeshi; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        Journal of Physiological Sciences, Mar. 2017, (一社)日本生理学会
      • Requirement of Discontinuation of Amiodarone for Lethal Arrhythmias
        KOHJITANI Hirohiko; KOBORI Atsushi; SASAKI Yasuhiro; KIM Kitae; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka
        Journal of Arrhythmia, Jun. 2013, (一社)日本不整脈心電学会
      • Prevalence and Location of J-wave in Patients with Implantable Cardioverter Defibrillator
        KOHJITANI Hirohiko; KOBORI Atsushi; KIM Kite; KITAI Takeshi; EHARA Natsuhiko; KINOSHITA Makoto; KAJI Shuichiro; TANI Tomoko; FURUKAWA Yutaka; KITA Toru
        Circulation Journal, Mar. 2013, (一社)日本循環器学会
      • ICD記録により心室頻拍の誘発様式が判明し,心房細動アブレーションが奏効した1例
        糀谷泰彦; 小堀敦志; 村井亮介; 吉澤尚志; 羽渓健; 井手裕也; 豊田俊彬; 佐々木康博; 金基泰; 北井豪; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕; 北徹
        日本循環器学会近畿地方会(Web), 2013
      • 致死性不整脈に対するアミオダロン静注から内服への切り替え状況の検討
        糀谷泰彦; 小堀敦志; 羽渓健; 豊田俊彬; 井手裕也; 本田怜史; 西野共達; KIM K.; 北井豪; 江原夏彦; 木下愼; 加地修一郎; 山室淳; 谷知子; 古川裕
        Progress in Medicine, 2012, (株)ライフ・サイエンス
      • 78歳まで根治術なしに生存し得たファロー四徴症の1例
        糀谷泰彦; 山室淳; 金基泰; 羽渓健; 北井豪; 小堀敦志; 江原夏彦; 木下慎; 加地修一郎; 谷知子; 古川裕
        日本循環器学会近畿地方会(Web), 2012
      • Posterior reversible encephalopathy syndrome (PRES) as a rare complication of coronary/aortic angiography: A case report
        KOHJITANI Hirohiko; EHARA Natsuhiko; KIM Kitae; KITAI Takeshi; KOBORI Atsushi; KINOSHITA Makoto; KAJI Shuichiro; YAMAMURO Atsushi; TANI Tomoko; FURUKAWA Yutaka
        日本心血管インターベンション治療学会誌, Jun. 2012, (一社)日本心血管インターベンション治療学会
      • 急性膵炎として加療されていた劇症1型糖尿病の1例
        糀谷泰彦; 本庶祥子; 森可南子; 浜本芳之; 河崎祐貴子; 和田良春; 越山裕行
        糖尿病, 2011, (一社)日本糖尿病学会
      • 脳原発hemangiopericytomaの肝転移に対して肝拡大右葉切除術を施行した一例
        糀谷泰彦; 多田正晴; 寺嶋宏明; 中西保貴; 吉村弥緒; 高橋英雄; 吉田昌弘; 吉冨摩美; 上田修吾; 橋田裕毅; 尾崎信弘
        日本肝胆膵外科学会・学術集会プログラム・抄録集, 2010, (一社)日本肝胆膵外科学会
      • 機械学習を用いた遺伝性不整脈疾患の予後予測モデルの開発(Development of a Genetic Prognostic Model for Hereditary Arrhythmia Disease Using Machine Learning)
        Kohjitani Hirohiko; Mitani Takeshi; Aizawa Takanori; Makiyama Takeru; Kashiwa Asami; Imamura Tomohiko; Ohno Seiko; Horie Minoru; Shizuta Satoshi; Kimura Takeshi; Okuno Yasushi
        日本循環器学会学術集会抄録集, Mar. 2022, (一社)日本循環器学会
      • 複雑な疾患メカニズムの解明における数理モデルとiPS細胞を利用した細胞工学を組み合わせた技術の有用性(Usefulness of Combination of Mathematical Modeling and Cell Engineering Using Induced Pluripotent Stem Cells for Revealing Complex Disease Mechanism)
        糀谷 泰彦; 柏 麻美; 野間 昭典; 牧山 武; 豊田 太; 山本 雄大; 烏日揚海 伊敏; 堀江 稔; 大野 聖子; 高 景山; 黄 海; 今村 知彦; 相澤 卓範; 静田 聡; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020, (一社)日本循環器学会
      • 人工知能による細胞特異的hiPSC-CMsのシミュレーションと薬物試験予測の最適化手法(Artificial Intelligence Based Optimization System for Cell-specific hiPSC-CMs Simulation and Prediction of Drug Testing)
        Kohjitani Hirohiko; Makiyama Takeru; Yamamoto Yuta; Yimin Wuriyanghai; Yoshinaga Daisuke; Kashiwa Asami; Imamura Tomohiko; Aizawa Takanori; Gao Jingshan; Huang Hai; Shizuta Satoshi; Kimura Takeshi
        日本循環器学会学術集会抄録集, Jul. 2020, (一社)日本循環器学会
      • hiPSC-CMの細胞特異的で正確な数理モデルによって明らかにしたIKr電流遮断試験における二つのAPD反作用(Cell-specific Precise Mathematical Modeling of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test)
        Kohjitani Hirohiko; Koda Shigeya; Himeno Yukiko; Makiyama Takeru; Kimura Takeshi; Noma Akinori; Amano Akira
        The Journal of Physiological Sciences, Mar. 2018, (一社)日本生理学会
      • hiPSC-CMの細胞特異的で精密な数学的モデリングによりIKr遮断試験における二つの正反対のAPD反応が明らかになった(Cell-Specific Precise Mathematical Modeling of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test)
        Kohjitani Hirohiko; Koda Shigeya; Himeno Yukiko; Makiyama Takeru; Yokoi Fumika; Hirose Sayako; Wuriyanghai Yimin; Yamamoto Yuta; Horie Minoru; Kimura Takeshi; Noma Akinori; Amano Akira
        日本循環器学会学術集会抄録集, Mar. 2018, (一社)日本循環器学会
      • Cell-specific Precise Computer Simulation of hiPSC-CMs Revealed Two Opposite APD Reaction in IKr Blocking Test
        KOHJITANI Hirohiko; KOUDA Shigeya; HIMENO Yukiko; MAKIYAMA Takeru; YOKOI Fumika; HIROSE Sayako; WURIYANGHAI Yimin; YAMAMOTO Yuta; HORIE Minoru; KIMURA Takeshi; NOMA Akinori; AMANO Akira
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2018
      • ヒトiPS由来心筋細胞の数理モデルの構築と心室筋・心房筋・洞結節様細胞の解析(Mathematical modeling and analysis of electrophysiological characteristics of the ventricular, atrial, and nodal-like hiPSC-CMs)
        Kohjitani Hirohiko; Kouda Shigeya; Himeno Yukiko; Yamamoto Natsuki; Makiyama Takeru; Harita Takeshi; Kimura Takeshi; Noma Akinori; Amano Akira
        The Journal of Physiological Sciences, Mar. 2017, (一社)日本生理学会
      • Patient-Specific Induced Pluripotent Stem-Cell Models for Long QT Syndrome with the Missense Mutation in the KCNH2 Gene
        KOHJITANI Hirohiko; MAKIYAMA Takeru; SASAKI Kenichi; HIROSE Sayako; NISHIUCHI Suguru; HAYANO Mamoru; HARITA Takeshi; YAMAMOTO Yuta; WURIYANGHAI Yimin; OHNO Seiko; HORIE Minoru; KIMURA Takeshi
        日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016
      • Genetic Backgrounds of Patients with Clinically Diagnosed Idiopathic Ventricular Fibrillation
        KOHJITANI Hirohiko; MAKIYAMA Takeru; SASAKI Kenichi; OHNO Seiko; WURIYANGHAI Yimin; HAYANO Mamoru; NISHIUCHI Suguru; YAMAMOTO Yuta; HARITA Takeshi; KIMURA Takeshi; HORIE Minoru
        Circulation Journal, 2015, (一社)日本循環器学会
      • Impact of J-wave in Patients With Structural Heart Disease
        Hirohiko Kohjitani; Atsushi Kobori; Yasuhiro Sasaki; Kitae Kim; Takeshi Kita; Natsuhiko Ehara; Makoto Kinoshita; Shuichiro Kaji; Tomoko Tani; Toru Kita; Yutaka Furukawa
        CIRCULATION, Nov. 2013, LIPPINCOTT WILLIAMS & WILKINS
      • 致死性の不整脈に対するアミオダロンの退薬の必要性(Requirement of Discontinuation of Amiodarone for Lethal Arrhythmias)
        Kohjitani Hirohiko; Kobori Atsushi; Sasaki Yasuhiro; Kim Kitae; Kitai Takeshi; Ehara Natsuhiko; Kinoshita Makoto; Kaji Shuichiro; Tani Tomoko; Furukawa Yutaka
        Journal of Arrhythmia, Jun. 2013, (一社)日本不整脈心電学会
      • 植込み型除細動器使用患者におけるJ波の頻度と部位(Prevalence and Location of J-wave in Patients with Implantable Cardioverter Defibrillator)
        Kohjitani Hirohiko; Kobori Atsushi; Kim Kite; Kitai Takeshi; Ehara Natsuhiko; Kinoshita Makoto; Kaji Shuichiro; Tani Tomoko; Furukawa Yutaka; Kita Toru
        Circulation Journal, Mar. 2013, (一社)日本循環器学会
      • 冠動脈・大動脈造影検査中に可逆性後頭葉白質脳症(PRES)を発症した1例(Posterior reversible encephalopathy syndrome (PRES) as a rare complication of coronary/aortic angiography: A case report)
        Kohjitani Hirohiko; Ehara Natsuhiko; Kim Kitae; Kitai Takeshi; Kobori Atsushi; Kinoshita Makoto; Kaji Shuichiro; Yamamuro Atsushi; Tani Tomoko; Furukawa Yutaka
        日本心血管インターベンション治療学会誌, Jun. 2012, (一社)日本心血管インターベンション治療学会
      • アミオダロン静注から内服に切り替えた致死的不整脈症例の特徴(Characteristics of Lethal Arrhythmia Cases Switched from Intravenous to Internal Use of Amiodarone)
        Kohjitani Hirohiko; Kobori Atsushi; Kim Kite; Kitai Takeshi; Kinoshita Makoto; Kaji Shujiro; Yamamuro Atsushi; Tani Tomoko; Furukawa Yutaka
        心電図, Sep. 2011, (一社)日本不整脈心電学会
      • Usefulness of Combination of Mathematical Modeling and Cell Engineering Using Induced Pluripotent Stem Cells for Revealing Complex Disease Mechanism(和訳中)
        糀谷 泰彦; 柏 麻美; 野間 昭典; 牧山 武; 豊田 太; 山本 雄大; 烏日揚海 伊敏; 堀江 稔; 大野 聖子; 高 景山; 黄 海; 今村 知彦; 相澤 卓範; 静田 聡; 木村 剛
        日本循環器学会学術集会抄録集, Jul. 2020, (一社)日本循環器学会
      • Artificial Intelligence Based Optimization System for Cell-specific hiPSC-CMs Simulation and Prediction of Drug Testing(和訳中)
        Kohjitani Hirohiko; Makiyama Takeru; Yamamoto Yuta; Yimin Wuriyanghai; Yoshinaga Daisuke; Kashiwa Asami; Imamura Tomohiko; Aizawa Takanori; Gao Jingshan; Huang Hai; Shizuta Satoshi; Kimura Takeshi
        日本循環器学会学術集会抄録集, Jul. 2020, (一社)日本循環器学会
      • ヒト多能性幹細胞由来心筋細胞のシミュレーションモデル開発によるペースメーカー機転の多重メカニズム解析(Multi-layer Cardiac Pacemaker Mechanisms demonstrated in Human Induced Pluripotent Stem Cells by Developing Mathematical Cell Models)
        Kohjitani Hirohiko; Koda Shigeya; Himeno Yukiko; Makiyama Takeru; Yamamoto Yuta; Wuriyanghai Yimin; Yoshinaga Daisuke; Kashiwa Asami; Amano Akira; Noma Akinori; Kimura Takeshi
        The Journal of Physiological Sciences, Mar. 2020, (一社)日本生理学会
      • hiPSC-CMシミュレーションのアルゴリズム的自動再生システムと薬剤検査の予測(Algorithmic Auto-recreation System of hiPSC-CMs Simulation and Prediction of Drug Testing)
        糀谷 泰彦
        日本循環器学会学術集会抄録集, Mar. 2019, (一社)日本循環器学会
      • ヒトiPS由来分化心筋の数理モデルを用いた細胞特異的な活動電位波形の再現とIKr電流遮断シミュレーションによる反応性の検討
        糀谷泰彦; 幸田茂也; 姫野友紀子; 牧山武; 木村剛; 野間昭典; 天野晃
        心電図, 2019, (一社)日本不整脈心電学会
      • 経皮的ASD閉鎖術の術前・術後に経皮的カテーテル心筋焼灼術を施行した1例
        糀谷泰彦; 静田聡; 中井久登; 田中宗和; 山上新太郎; 相澤卓範; 小正晃裕; 吉澤尚志; 牧山武; 木村剛
        日本不整脈心電学会カテーテルアブレーション委員会公開研究会プログラム・抄録集, 2019
      • Novel Mathematical Models of All Subtypes of Induced Pluripotent Stem Cell Derived Cardiomyocytes
        Hirohiko Kohjitani; Shigeya Koda; Yukiko Himeno; Takeru Makiyama; Fumika Yokoi; Sayako Hirose; Yimin Wuriyanghai; Yuta Yamamoto; Minoru Horie; Takeshi Kimura; Akinori Noma; Akira Amano
        CIRCULATION, Nov. 2017, LIPPINCOTT WILLIAMS & WILKINS
      • Characteristics of Lethal Arrhythmia Cases Switched from Intravenous to Internal Use of Amiodarone
        Hirohiko Kohjitani; Atsushi Kobori; Kite Kim; Takeshi Kitai; Makoto Kinoshita; Shujiro Kaji; Atsushi Yamamuro; Tomoko Tani; Yutaka Furukawa
        journal of arrhythmia, 2011

      Books and Other Publications

      • Policy makers lab Journal vol.4
        Hirohiko Kohjitani, Single work
        Policy Makers Lab, Dec. 2023
      • Japanese Journal of Clinical Medicine
        糀谷泰彦; 小清水宏; 中村和貴; 奥野恭史, Contributor, AI development for hypertension therapy
        Nippon Rinsho, Jan. 2023
      • 徹底探索心エコー : 症例と画像で学ぶ心エコー図重要ポイント
        谷 知子; 古川 裕, Contributor, 先天性心疾患
        日本医事新報社, May 2013
        Find Kyoto University's collection of books :

      Industrial Property Rights

      • 特願2023-084755, Computer program, intracardiac electrocardiogram evaluation device, intracardiac electrocardiogram evaluation system, intracardiac electrocardiogram evaluation method, and learning model generation method
        Hirohiko Kohjitani; Munekazu Tanaka; Satoshi Shizuta; Yasushi Okuno
      • 特開2019-170175(P2019-170175A), 特願2018-59605(P2018-59605), 活動電位測定誤差の補正方法、解析装置、及びコンピュータプログラム
        野間 昭典; 幸田 茂也; 糀谷 泰彦

      External funds: Kakenhi

      • Establishment of an Optimization Method for Organ Extraction from Non-Contrast CT Using Deep Learning
        Grant-in-Aid for Scientific Research (C)
        Basic Section 53020:Cardiology-related
        Kyoto University
        静田 聡
        From 01 Apr. 2021, To 31 Mar. 2025, Granted
        カテーテル・アブレーション;造影CT;心房細動;ディープ・ラーニング;医用画像処理;ディープニューラルネットワーク;3D-CNN;VAE;循環器内科;ディープラーニング
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K08026/
      • Development of Mathematical Model of hiPSC-CMs for Drug Discovery and Analysis of Genetic Diseases
        Grant-in-Aid for Early-Career Scientists
        Basic Section 53020:Cardiology-related
        Kyoto University
        Hirohiko Kohjitani
        From 01 Apr. 2019, To 31 Mar. 2023, Project Closed
        コンピュータ・シミュレーション;数理モデル;hiPSC-CMs;イオンチャネル;数理最適化;機械学習;数理モデリング;パッチクランプ;ペースメーカー機転;ヒトiPS細胞由来分化心筋;安全性薬理試験
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K17560/
      • Development of a crossover electrophysiological analysis system integrating AI and mathematical modeling
        Grant-in-Aid for Early-Career Scientists
        Basic Section 53020:Cardiology-related
        Kyoto University
        糀谷 泰彦
        From 01 Apr. 2023, To 31 Mar. 2026, Granted
        不整脈;カテーテルアブレーション;細胞電気生理学;数理モデル;コンピュータシミュレーション;医療AI開発;医療AI;心電図;深層学習;コンピュータ・シミュレーション
        https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K15155/

      External funds: others

      • 12誘導心電図からの心内心電図情報予測に基づく不整脈疾患精密診断プログラムの開発研究 (2024年度分)
        経済産業省, 医療研究開発推進事業費補助金
        From 01 Apr. 2024, To 31 Mar. 2025
        代表
      • 12誘導心電図からの心内心電図情報予測に基づく不整脈疾患精密診断プログラムの開発研究 (2023年度分)
        経済産業省, 医療研究開発推進事業費補助金
        From 01 Apr. 2023, To 31 Mar. 2024
        代表
      list
        Last Updated :2025/06/08

        Education

        Teaching subject(s)

        • From 01 Apr. 2025, To 31 Mar. 2026
          Big data science in medicine
          3236, Fall, Faculty of Medicine, 1
        • From 01 Apr. 2025, To 31 Mar. 2026
          Clinical Overview of Medicine A
          3223, Spring, Faculty of Medicine, 1

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