Basic Information

Affiliated programs (koza)

• Graduate School of Agriculture, 応用生命科学専攻 生体分子機能講座, 助教

Academic Degree

• 修士（農学）(名古屋大学)
• 博士（農学）(名古屋大学)

ID,URL

• J-Global ID

  201501074796250550

researchmap URL

• https://researchmap.jp/7000011386

Research

Research Topics, Overview of the research

• Research Topics

  Metabolism of phospholipids and omega-3 polyunsaturated fatty acids
  Molecular mechanism of cold-adaptation in bacteria

• Overview of the research

  Omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are food ingredients beneficial to human health. Also, microorganisms are known to produce EPA and DHA for its biological activities. My research deals with the EPA-producing, psychrotrophic bacterium Shewanella livingstonensis Ac10 to reveal its production mechanism of EPA and EPA-containing phospholipids and ability of metabolically converting omega-3 polyunsaturated fatty acids through biochemical analyses. Through these studies, I aim to understand its adaptability to cold environments at molecular level and to find and develop novel bacterial functions.

Research Areas

• Life sciences, Applied microbiology

Papers

• Enhancing extracellular membrane vesicle productivity of Shewanella vesiculosa HM13, a prospective host for vesiculation-mediated protein secretion, by weakening outer membrane-peptidoglycan linkage

  Mengshan Zhu; Jun Kawamoto; Tomoya Imai; Takuya Ogawa; Tatsuo Kurihara

  Journal of Bioscience and Bioengineering, Aug. 2024, Peer-reviewed

  
• Rapid screening and identification of genes involved in bacterial extracellular membrane vesicle production using a curvature-sensing peptide

  Hiromu Inoue; Kenichi Kawano; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara

  20 May 2024

  
• Capsular polysaccharide-mediated protein loading onto extracellular membrane vesicles of a fish intestinal bacterium,Shewanella vesiculosaHM13

  Kouhei Kamasaka; Jun Kawamoto; Taiku Tsudzuki; Yuying Liu; Tomoya Imai; Takuya Ogawa; Tatsuo Kurihara

  bioRxiv, 26 Apr. 2023

  
• Structural factors governing binding of curvature-sensing peptides to bacterial extracellular vesicles covered with hydrophilic polysaccharide chains

  Kenichi Kawano; Kouhei Kamasaka; Fumiaki Yokoyama; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara; Katsumi Matsuzaki

  Biophysical Chemistry, May 2023

  Access this paper :

  
• Division of the role and physiological impact of multiple lysophosphatidic acid acyltransferase paralogs

  Takuya Ogawa; Misaki Kuboshima; Nittikarn Suwanawat; Jun Kawamoto; Tatsuo Kurihara

  BMC Microbiology, 06 Oct. 2022, Peer-reviewed, Lead author

  Access this paper :

  
• Capsular polysaccharide from a fish-gut bacterium induces/promotes apoptosis of colon cancer cells in vitro through Caspases' pathway activation

  Rossella Di Guida; Angela Casillo; Antonietta Stellavato; Soichiro Kawai; Takuya Ogawa; Celeste Di Meo; Jun Kawamoto; Tatsuo Kurihara; Chiara Schiraldi; Maria Michela Corsaro

  Carbohydrate Polymers, Feb. 2022, Peer-reviewed

  
• Complete Lipooligosaccharide Structure from Pseudoalteromonas nigrifaciens Sq02-Rifr and Study of Its Immunomodulatory Activity

  Rossella Di Guida; Angela Casillo; Antonietta Stellavato; Celeste Di Meo; Soichiro Kawai; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara; Chiara Schiraldi; Maria Michela Corsaro

  Marine Drugs, 19 Nov. 2021, Peer-reviewed

  
• Design of the N-Terminus Substituted Curvature-Sensing Peptides That Exhibit Highly Sensitive Detection Ability of Bacterial Extracellular Vesicles

  Kenichi Kawano; Fumiaki Yokoyama; Kouhei Kamasaka; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara; Shiroh Futaki

  Chemical and Pharmaceutical Bulletin, 01 Nov. 2021, Peer-reviewed

  
• Initial step of selenite reduction via thioredoxin for bacterial selenoprotein biosynthesis

  Atsuki Shimizu; Ryuta Tobe; Riku Aono; Masao Inoue; Satoru Hagita; Kaito Kiriyama; Yosuke Toyotake; Takuya Ogawa; Tatsuo Kurihara; Kei Goto; N. Tejo Prakash; Hisaaki Mihara

  International Journal of Molecular Sciences, 02 Oct. 2021

  
• Development of a Simple and Rapid Method for In Situ Vesicle Detection in Cultured Media.

  Kenichi Kawano; Fumiaki Yokoyama; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara; Shiroh Futaki

  Journal of molecular biology, 12 Sep. 2020, Peer-reviewed

  
• Role of acyl-CoA dehydrogenases from Shewanella livingstonensis Ac10 in docosahexaenoic acid conversion.

  Yustina Yusuf; Takuya Ogawa; Jun Kawamoto; Tatsuo Kurihara

  Biochemical and biophysical research communications, 30 Jul. 2020, Peer-reviewed

  
• Lysophosphatidic acid acyltransferase from the thermophilic bacterium Thermus thermophilus HB8 displays substrate promiscuity

  Takuya Ogawa; Nittikarn Suwanawat; Yosuke Toyotake; Bunta Watanabe; Jun Kawamoto; Tatsuo Kurihara

  Bioscience, Biotechnology, and Biochemistry, 26 May 2020, Peer-reviewed, Lead author

  
• A Novel Lysophosphatidic Acid Acyltransferase of Escherichia coli Produces Membrane Phospholipids with a cis-vaccenoyl Group and Is Related to Flagellar Formation.

  Yosuke Toyotake; Masayoshi Nishiyama; Fumiaki Yokoyama; Takuya Ogawa; Jun Kawamoto; Tatsuo Kurihara

  Biomolecules, 11 May 2020, Peer-reviewed

  
• Bioconversion From Docosahexaenoic Acid to Eicosapentaenoic Acid in the Marine Bacterium Shewanella livingstonensis Ac10.

  Takuya Ogawa; Kazuki Hirose; Yustina Yusuf; Jun Kawamoto; Tatsuo Kurihara

  Frontiers in microbiology, 2020, Peer-reviewed

  
• Genetic characterization and functional implications of the gene cluster for selective protein transport to extracellular membrane vesicles of Shewanella vesiculosa HM13

  Kouhei Kamasaka; Jun Kawamoto; Chen Chen; Fumiaki Yokoyama; Tomoya Imai; Takuya Ogawa; Tatsuo Kurihara

  Biochemical and Biophysical Research Communications, 2020, Peer-reviewed

  
• Development of a regulatable low-temperature protein expression system using the psychrotrophic bacterium, Shewanella livingstonensis Ac10, as the host

  Soichiro Kawai; Jun Kawamoto; Takuya Ogawa; Tatsuo Kurihara

  Bioscience, Biotechnology, and Biochemistry, 02 Nov. 2019, Peer-reviewed

  Access this paper :

  
• Purification and characterization of 1-acyl-sn-glycerol-3-phosphate acyltransferase with a substrate preference for polyunsaturated fatty acyl donors from the eicosapentaenoic acid-producing bacterium Shewanella livingstonensis Ac10

  Takuya Ogawa; Asako Tanaka; Jun Kawamoto; Tatsuo Kurihara

  Journal of Biochemistry, Jul. 2018, Peer-reviewed, Lead author

  
• 細菌におけるω3長鎖高度不飽和脂肪酸の生合成と生理機能

  栗原 達夫; 川本 純; 小川 拓哉

  ビタミン, 2017, Peer-reviewed, Invited

  
• A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation

  Takuya Ogawa; Koh-ichi Emi; Kazushi Koga; Tohru Yoshimura; Hisashi Hemmi

  FEBS JOURNAL, Jun. 2016, Peer-reviewed

  
• A phytoene desaturase homolog gene from the methanogenic archaeon Methanosarcina acetivorans is responsible for hydroxyarchaeol biosynthesis

  Takeshi Mori; Keisuke Isobe; Takuya Ogawa; Tohru Yoshimura; Hisashi Hemmi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 2015, Peer-reviewed

  
• A highly selective biosynthetic pathway to non-natural C-50 carotenoids assembled from moderately selective enzymes

  Maiko Furubayashi; Mayu Ikezumi; Shinichi Takaichi; Takashi Maoka; Hisashi Hemmi; Takuya Ogawa; Kyoichi Saito; Alexander V. Tobias; Daisuke Umeno

  NATURE COMMUNICATIONS, Jul. 2015, Peer-reviewed

  
• A novel geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans displays unique regiospecificity

  Takuya Ogawa; Keisuke Isobe; Takeshi Mori; Susumu Asakawa; Tohru Yoshimura; Hisashi Hemmi

  FEBS JOURNAL, Jul. 2014, Peer-reviewed

  
• Geranylgeranyl Reductase and Ferredoxin from Methanosarcina acetivorans Are Required for the Synthesis of Fully Reduced Archaeal Membrane Lipid in Escherichia coli Cells

  Keisuke Isobe; Takuya Ogawa; Kana Hirose; Takeru Yokoi; Tohru Yoshimura; Hisashi Hemmi

  JOURNAL OF BACTERIOLOGY, Jan. 2014, Peer-reviewed

  
• Substrate specificity of undecaprenyl diphosphate synthase from the hyperthermophilic archaeon Aeropyrum pernix

  Takeshi Mori; Takuya Ogawa; Tohru Yoshimura; Hisashi Hemmi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2013, Peer-reviewed

  
• Connected cavity structure enables prenyl elongation across the dimer interface in mutated geranylfarnesyl diphosphate synthase from Methanosarcina mazei

  Takuya Ogawa; Tohru Yoshimura; Hisashi Hemmi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2011, Peer-reviewed

  
• Geranylfarnesyl diphosphate synthase from Methanosarcina mazei: Different role, different evolution

  Takuya Ogawa; Tohru Yoshimura; Hisashi Hemmi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2010, Peer-reviewed

  

Misc.

• 核酸含量から見た細菌細胞外膜小胞の多様性とそれらの生産に関わる遺伝子群

  井上宙夢; 河野健一; 川本純; 小川拓哉; 栗原達夫

  日本生化学会大会(Web), 2023

  
• Shewanella vesiculosa HM13の細胞外膜小胞生産関連遺伝子の生理機能解析

  井上宙夢; 河野健一; 川本純; 小川拓哉; 栗原達夫

  日本農芸化学会関西支部講演会講演要旨集, 2023

  
• Analysis of the conversion of docosahexaenoic acid to eicosapentaenoic acid by β-oxidation enzymes in Shewanella livingstonensis Ac10

  正木翼加; 小川拓哉; 川本純; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2023

  
• Analysis of surface polysaccharide synthesis enzymes involved in the cargo transport to extracellular membrane vesicles of Shewanella vesiculosa HM13

  都築大空; 今井友也; 川本純; 小川拓哉; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2023

  
• Screening and functional prediction of genes related to membrane vesicle production of Shewanella vesiculosa HM13 using a curvature-sensing peptide

  井上宙夢; 河野健一; 川本純; 小川拓哉; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2023

  
• Analysis of the physiological functions of a surface protein on extracellular membrane vesicles of Shewanella vesiculosa HM13

  釜阪紘平; 川本純; 小川拓哉; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2023

  
• 糖鎖に覆われた細胞外小胞膜に結合する曲率認識ペプチドの構造的柔軟性の重要さ

  河野健一; 釜阪紘平; 横山文秋; 横山文秋; 川本純; 小川拓哉; 栗原達夫; 松崎勝巳

  生体膜と薬物の相互作用シンポジウム講演要旨集, 2023

  
• 表層多糖が関与する細菌の細胞外膜小胞生産

  都築大空; 今井友也; 川本純; 小川拓哉; 栗原達夫

  日本生化学会大会(Web), 2023

  
• 細菌における細胞外膜小胞生産の分子基盤

  栗原達夫; 川本純; 小川拓哉

  日本生化学会大会(Web), 2023

  
• Biding characteristics of a curvature-sensing peptide recognizing bacterial extracellular membrane vesicles

  阪本大輝; 井上宙夢; 河野健一; 今井友也; 川本純; 小川拓哉; 倉田淳志; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2023

  
• 蛍光共鳴エネルギー移動を用いた曲率認識ペプチドによる細胞外小胞の高感度検出法の開発

  河野健一; 横山文秋; 横山文秋; 小川拓哉; 川本純; 栗原達夫; 松崎勝巳

  次世代を担う若手のためのフィジカル・ファーマフォーラム講演要旨集, 2022

  
• 細胞外膜小胞への積荷タンパク質輸送に関与する表層糖鎖合成酵素ホモログの機能

  都築大空; 今井友也; 川本純; 小川拓哉; 栗原達夫

  日本生化学会大会(Web), 2022

  
• Escherichia coli由来新規リゾホスファチジン酸アシル基転移酵素YihGの基質特異性と生理機能解析

  豊竹洋佑; 川本純; 西山雅祥; 小川拓哉; 栗原達夫

  日本農芸化学会大会講演要旨集(Web), 2019

  
• 新規リゾホスファチジン酸アシル基転移酵素YihGのEscherichia coli膜リン脂質生合成への寄与とその生理機能

  豊竹洋佑; 川本純; 西山雅祥; 小川拓哉; 栗原達夫

  日本生化学会大会(Web), 2018

  
• 海洋性Shewanella属細菌によるω-3系高度不飽和脂肪酸の変換経路の解明

  小川 拓哉; 廣瀬 和樹; 川本 純; 栗原 達夫

  第66回日本生化学会近畿支部例会, May 2019

  
• 低温菌Shewanella livingstonensis Ac10におけるドコサヘキサエン酸からエイコサペンタエン酸への変換機構の解析

  廣瀬 和樹; 小川 拓哉; 川本 純; 栗原 達夫

  極限環境生物学会第19会例会, Dec. 2018

  
• PURIFICATION AND CHARACTERIZATION OF 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE THAT PRODUCES EICOSAPENTAENOIC ACID-CONTAINING PHOSPHOLIPIDS

  小川 拓哉; 田中 麻子; 川本 純; 栗原 達夫

  Extremophiles 2018, 16 Sep. 2018

  
• 低温菌Pseudoalteromonas sp. Sq02株を用いたタンパク質低温生産システムの開発

  河合総一郎; Aken Puti Wanguyun; 川本 純; 小川拓哉; 栗原達夫

  日本生化学会第65回近畿支部例会, 26 May 2018

  
• 低温菌 Shewanella sp. HM13の膜小胞輸送による選択的タンパク質分泌に関与する遺伝子の探索

  釜阪 紘平; Chen CHEN; 横山 文秋; 川本 純; 今井 友也; 小川 拓哉; 栗原 達夫

  日本農芸化学会 2018 年度大会, 16 Mar. 2018

  
• 低温菌における機能性多価不飽和脂肪酸の細胞内局在の可視化

  川本純; 徳永智久; 渡辺文太; 小川拓哉; 栗原達夫

  日本農芸化学会2018年度大会，名古屋, 16 Mar. 2018

  
• 好熱菌 Thermus thermophilus 由来 リゾホスファチジン酸アシル基転移酵素の基質特異性の解析

  小川 拓哉; Nittikarn Suwanawa; 豊竹 洋佑; 渡辺 文太; 川本 純; 栗原 達夫

  日本農芸化学会2018年度大会, Mar. 2018

  
• Purification and characterization of a lysophosphatidic acid acyltransferase from an eicosapentaenoic acid-producing bacterium Shewanella livingstonensis Ac10

  小川 拓哉

  International workshop on microbes in hostile environments, Dec. 2017, Invited

  
• EPA 生産菌Shewanella livingstonensis Ac10 のリゾホスファチジン酸アシル基転移酵素の精製と 特性評価

  小川 拓哉; 田中 麻子; 川本 純; 栗原 達夫

  特殊環境微生物セミナー 2017, Oct. 2017

  
• Purification and characterization of a thermostable 1-acyl-sn-glycerol-3-phosphate acyltransferase (PlsC)

  Nittikarn Suwanawat; Takuya Ogawa; Asako Tanaka; Jun Kawamoto; Tatsuo Kurihara

  2017年度酵素補酵素研究会, Jun. 2017

  
• 細菌型リゾホスファチジン酸アシル基転移酵素の精製とキャラクタリゼーション

  小川 拓哉; 田中麻子; Nittikarn Suwanawat; 川本純; 栗原達夫

  第64回日本生化学会近畿支部例会, May 2017

  
• 細菌におけるエイコサペンタエン酸の生理機能

  栗原達夫; 川本純; 渡辺文太; 小川拓哉

  日本農芸化学会2017年度大会，京都, 20 Mar. 2017

  
• Interaction between proteins involved in the biosynthesis of EPA-containing phospholipids in a psychrotrophic bacterium, Shewanella livingstonensis Ac10

  Chen Tsai-Min; Ryutaro OGURA; Takuya OGAWA; Jun KAWAMOTO; Tatsuo KURIHARA

  日本農芸化学会 2017 年度大会, 17 Mar. 2017

  
• 低温性Shewanella属細菌の色素生産に関与するリゾホスファチジン酸アシル基転移酵素ホモログの機能解析

  小川 拓哉; 太田昌希; 川本純; 栗原達夫

  日本農芸化学会2017年度大会, Mar. 2017

  
• 低温性Shewanella属細菌由来1-アシル-sn-グリセロール-3-リン酸アシル基転移酵素PlsCの酵素学的特性解析

  小川 拓哉; 田中麻子; 川本純; 栗原達夫

  第17回極限環境生物学会年会, Nov. 2016

  
• 低温菌 Shewanella livingstonensis Ac10 による菌体外膜小胞の生産とエイコサペンタエン酸生産能の欠損が膜小胞分泌におよぼす影響

  横山文秋; 今井友也; 川本 純; 小川拓哉; 栗原達夫

  第89回日本生化学会大会, 25 Sep. 2016

  
• Molecular Characterization of Eicosapentaenoic Acid-Containing Membrane Vesicles Produced by a Psychrotrophic Bacterium, Shewanella livistonensis Ac10

  Yokoyama Fumiaki; Jun Kawamoto; Tomoya Imai; Takuya Ogawa; Tatsuo Kurihara

  Extremophiles 2016 11th International Congress on Extremophiles, 12 Sep. 2016

  
• 真正細菌型1-アシルグリセロール-3-リン酸アシル基転移酵素PlsCの精製と酵素学的特性解析

  小川 拓哉; 田中麻子; 川本純; 栗原達夫

  第89回日本生化学会大会, Sep. 2016

  
• Purification and enzymatic characterization of bacterial 1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC

  小川 拓哉; 田中麻子; 川本純; 栗原達夫

  The Fifth International Conference on Cofactors & Active Enzyme Molecule 2016, Sep. 2016

  
• 低温菌 Shewanella livingstonensis Ac10 の菌体外膜小胞の特性とエイコサペンタエン酸が小胞形成に与える影響の解析

  横山文秋; 今井友也; 川本 純; 小川拓哉; 栗原達夫

  第63回 日本生化学会 近畿支部例会, 21 May 2016

  
• 低温菌 Shewanella livingstonensis Ac10 の菌体外膜小胞の解析

  横山 文秋; 川本 純; 今井 友也; 小川 拓哉; 栗原 達夫

  日本農芸化学会2016年度大会, Mar. 2016

  
• メタン生成アーキア由来のシス型プレニルトランスフェラーゼホモログに触媒されるhead-to-tail型およびnon-head-to-tail型縮合

  小川拓哉; 吉村徹; 邊見久

  日本農芸化学会2015年度大会, Mar. 2015

  
• Identification and application of a novel, regiospecific geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans

  小川拓哉; 磯部圭祐; 浅川晋; 吉村徹; 邊見久

  持続可能社会構築のための酵素と微生物の科学と工学に関する新潮流 日本−イタリアシンポジウム, Nov. 2014

  
• Creation of unnatural compounds using a novel geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans

  小川拓哉; 磯部圭祐; 森健; 浅川晋; 吉村徹; 邊見久

  第87回日本生化学会大会, Oct. 2014

  
• メタン生成アーキア由来のω-末端特異的ゲラニルゲラニル基還元酵素

  小川拓哉; 磯部圭祐; 森健; 浅川晋; 吉村徹; 邊見久

  第24回イソプレノイド研究会例会, Sep. 2014

  
• メタン生成アーキア由来新奇プレニル基還元酵素の生理的役割

  小川拓哉; 磯部圭祐; 吉村徹; 邊見久

  日本ビタミン学会第66回大会, Jun. 2014

  
• Exploring novel enzymes involved in archaeal membrane lipid biosynthesis

  小川拓哉; 磯部圭祐; 吉村徹; 邊見久

  Archaea: Ecology, Metabolism & Molecular Biology, Jul. 2013

  
• アーキア膜脂質生合成に関わる新奇フラビン酵素（２）

  小川拓哉; 磯部圭祐; 吉村徹; 邊見久

  日本ビタミン学会第65回大会, May 2013

  
• 1P-052 Functional analysis of prenyl diphosphate synthases from the hyperthermophilic archaeon Aeropyrum pernix

  Mori Takeshi; Ogawa Takuya; Yoshimura Tohru; Hemmi Hisashi

  日本生物工学会大会講演要旨集, 2013

  
• Chain length determination mechanism of geranylfarnesyl diphosphate synthase from methanogenic archaeon Methanosarcina mazei

  小川拓哉; 吉村徹; 邊見久

  The International Conference of Natural Product Biosynthesis, Jun. 2012

  
• Construction of long-chain prenyl diphosphate synthase by connecting cavities between subunits

  小川拓哉; 吉村徹; 邊見久

  第84回日本生化学会大会, Sep. 2011

  
• メタン生成アーキア由来ゲラニルファルネシル二リン酸合成酵素の生成物鎖長決定機構

  小川拓哉; 吉村徹; 邊見久

  第20回ドリコールおよびイソプレノイド研究会例会, Sep. 2010

  
• メタン生成アーキア由来ゲラニルファルネシル二リン酸合成酵素

  小川拓哉; 吉村徹; 邊見久

  日本農芸化学会2010年度大会, Mar. 2010

  

Presentations

• 海洋性細菌における高度不飽和脂肪酸の代謝と生理機能

  小川拓哉

  第23回マリンバイオテクノロジー学会大会, 27 May 2023, Invited

  
• Unique membrane phospholipids that control bacterial physiology

  Takuya Ogawa

  第95回日本生化学会大会, 10 Nov. 2022, Invited

  
• Shewanella属細菌の低温適応に重要なエイコサペンタエン酸含有リン脂質の巧みな生合成機構

  小川 拓哉

  日本生化学会第９１回大会, 24 Sep. 2018, Invited

  

Books and Other Publications

• リゾホスファチジン酸アシル基転移酵素による細菌の生体膜脂肪酸組成の調節

  小川拓哉, Single work

  日本膜学会, Sep. 2023

  
• EPA、DHAをつくる有用細菌

  小川拓哉, Single work

  日本生物工学会, Oct. 2019

  
• 細菌におけるω3長鎖高度不飽和脂肪酸の生合成と生理機能

  栗原 達夫; 川本 純; 小川 拓哉, Joint work

  日本ビタミン学会, Sep. 2017, Not refereed

  

Awards

• 16 Oct. 2014

  日本生化学会大会, 若手優秀発表賞

External funds: Kakenhi

• Study on the metabolic conversion of omega-3 polyunsaturated fatty acids through a reconsideration of beta-oxidation pathway

  Grant-in-Aid for Scientific Research (C)

  Basic Section 38020:Applied microbiology-related

  Kyoto University

  小川 拓哉

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  ω-3高度不飽和脂肪酸;エイコサペンタエン酸;ドコサヘキサエン酸;微生物変換;β-酸化酵素;タンパク質間相互作用;β-酸化;転写調節;高度不飽和脂肪酸;生物変換;海洋性細菌;β酸化酵素;リン脂質アシル基転移酵素

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K05364/
• Exploration and Functional Elucidation of a Novel Protein Involved in the Metabolism of omega-3 Polyunsaturated Fatty Acids in Bacteria

  Grant-in-Aid for Early-Career Scientists

  Basic Section 38020:Applied microbiology-related

  Kyoto University

  Takuya Ogawa

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  ω-3系高度不飽和脂肪酸;脂質代謝;微生物変換;エイコサペンタエン酸;ドコサヘキサエン酸;β-酸化;ω3高度不飽和脂肪酸;ω-3高度不飽和脂肪酸;海洋性細菌;β酸化酵素;Shewanella;極限環境微生物;β酸化;Shewanella属細菌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K15733/
• Elucidation of the molecular basis for de novo phosphatidic acid synthesis through enzymological studies

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Takuya OGAWA

  From 01 Apr. 2017, To 31 Mar. 2020, Project Closed

  アシルグリセロールリン酸アシル基転移酵素;グリセロリン脂質;脂質代謝;リン脂質;細胞膜組成;阻害剤開発;PlsC;変異解析;アシル基転移酵素;膜タンパク質

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K15259/
• Studies on acyltransferases that create the heterogeneity of biological membrane in bacteria

  Grant-in-Aid for Research Activity Start-up

  Kyoto University

  Takuya Ogawa

  From 28 Aug. 2015, To 31 Mar. 2017, Project Closed

  リゾホスファチジン酸アシル基転移酵素;低温適応;脂質代謝;PlsC;膜タンパク質;リン脂質代謝;アシル基転移酵素;細胞膜生合成;リン脂質アシル基転移酵素;グリセロリン脂質;色素

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H06328/
• Mechanism of Biogenesis of Membrane Microdomain Containing Polyunsaturated Fatty Acids in Bacteria and Its Physiological Functions

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Tatsuo KURIHARA

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  生体膜;高度不飽和脂肪酸;エイコサペンタエン酸;リン脂質;アシル化タンパク質;マイクロドメイン;細菌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04474/
• 細菌が生体膜リン脂質を作り分ける生理的意義の理解とその応用

  Grant-in-Aid for Scientific Research (C)

  Basic Section 38020:Applied microbiology-related

  Kyoto University

  小川 拓哉

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  リン脂質;アシル基転移酵素;脂肪酸組成;生体膜

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K08682/

External funds: others

• 酵素的な生体膜脂質組成の改変とそれによる膜タンパク質の活性制御に関 する研究

  一般財団法人杉山報公会, 2024 年度 一般財団法人杉山報公会研究助成

  From 01 Apr. 2024, To 31 Mar. 2025

  小川拓哉
• ω3 系高度不飽和脂肪酸の微生物変換の解析とその応用に関する研究

  公益財団法人発酵研究所, 一般研究助成

  From 01 Apr. 2019, To 31 Mar. 2021

  小川拓哉

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Molecular Microbial Science

  CA17, Spring, Graduate School of Agriculture, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Molecular Microbial Science Seminar

  CF13, Fall, Graduate School of Agriculture, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Molecular Microbial Science Seminar

  CF13, Spring, Graduate School of Agriculture, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course of Molecular Microbial Science

  CG13, Spring, Graduate School of Agriculture, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course of Molecular Microbial Science

  CG13, Fall, Graduate School of Agriculture, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Microbial Science

  CA17, Spring, Graduate School of Agriculture, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Microbial Science Seminar1

  CB41, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Microbial Science Seminar2

  CB42, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course of Molecular Microbial Science1

  CC41, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course of Molecular Microbial Science2

  CC42, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Microbial Science Seminar1

  CB41, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course of Molecular Microbial Science1

  CC41, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course of Molecular Microbial Science2

  CC42, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Microbial Science Seminar2

  CB42, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Microbial Science

  CA17, Spring, Graduate School of Agriculture, 1
• From Apr. 2016, To Mar. 2017

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Experimental Course of Molecular Microbial Science

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Microbial Science Seminar

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Microbial Science

  Spring, 農学研究科
• From Apr. 2017, To Mar. 2018

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Experimental Course of Molecular Microbial Science

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Microbial Science Seminar

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Microbial Science

  Spring, 農学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Microbial Science

  Spring, 農学研究科
• From Apr. 2018, To Mar. 2019

  Fundamental Chemical Experiments

  Spring, 全学共通科目
• From Apr. 2019, To Mar. 2020

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Molecular Microbial Science

  Spring, 農学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Microbial Science

  Spring, 農学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course of Molecular Microbial Science1

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course of Molecular Microbial Science2

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Molecular Microbial Science Seminar1

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Molecular Microbial Science Seminar2

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Molecular Microbial Science

  Spring, 農学研究科

Administration

Faculty management (title, position)

• From 01 Apr. 2024, To 31 Mar. 2025

  化学研究所安全衛生委員会委員
• From 01 Apr. 2022, To 31 Mar. 2023

  化学研究所安全衛生委員会委員
• From 01 Apr. 2016, To 31 Mar. 2017

  化学研究所総務・教務委員会 委員