Basic Information

Professional Memberships

• 日本バイオイメージング学会
• 日本発生生物学会
• 日本細胞生物学会
• 日本分子生物学会

Academic Degree

• 理学修士(愛媛大学)
• 医学博士(大阪大学)

Academic Resume (Graduate Schools)

• 愛媛大学, 大学院理学研究科修士課程, 修了
• 大阪大学, 大学院医学研究科博士課程, 修了

Academic Resume (Undergraduate School/Majors)

• 愛媛大学, 理学部生物学科, 卒業

High School

• High School

  脇町高等学校

Language of Instruction

• English

ID,URL

• J-Global ID

  200901064812384682

Website(s) (URL(s))

• http://www.mcb.lif.kyoto-u.ac.jp

researchmap URL

• https://researchmap.jp/read0183915

Research

Research Interests

• 細胞死
• 高次生命現象
• cell death
• apoptosis

Research Areas

• Life sciences, Developmental biology
• Life sciences, Cell biology
• Life sciences, Molecular biology

Papers

• Caspase-mediated cleavage of a scaffold protein, MPRIP, yields a truncated form that is involved in repetitive bleb formation

  Kazuhiro Sakamaki; Naohisa Sakamoto; Yuki Tsujimura; Takahiro Iwasaki; Takuma Kawamura; Jun Nakabayashi; Rhea S. D'Souza; Arooma Jannat; Ken-ichiro Takeshima; Hiroyuki Takeda; Koji Koyamada; Hideo Yokota

  FEBS JOURNAL, 30 Jan. 2025

  
• The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis (vol 398, pg 777, 1999)

  Y Imai; T Kimura; A Murakami; N Yajima; K Sakamaki; S Yonehara

  NATURE, Jul. 1999

  
• INDUCTION OF ERYTHROID-SPECIFIC GENE-EXPRESSION IN LYMPHOID-CELLS

  T CHIBA; Y NAGATA; A KISHI; K SAKAMAKI; A MIYAJIMA; M YAMAMOTO; JD ENGEL; K TODOKORO

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Dec. 1993, Peer-reviewed

  
• Resolving structure and function of metaorganisms through a holistic framework combining reductionist and integrative approaches.

  C. Jaspers; S. Fraune; A.E. Arnold; D.J. Miller; T. Bosch; C.R. Voolstra; Consortium of Australian; Academy of; Science Boden; Research Conference Participants

  Zoology, 2019, Peer-reviewed

  
• Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage

  Kazuhiro Sakamaki; Takahiro M. Ishii; Toshiya Sakata; Kiwamu Takemoto; Chiyo Takagi; Ayako Takeuchi; Ryo Morishita; Hirotaka Takahashi; Akira Nozawa; Hajime Shinoda; Kumiko Chiba; Haruyo Sugimoto; Akiko Saito; Shuhei Tamate; Yutaka Satou; Sang-Kee Jung; Satoshi Matsuoka; Koji Koyamada; Tatsuya Sawasaki; Takeharu Nagai; Naoto Ueno

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, Nov. 2016, Peer-reviewed

  
• Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora

  Aurelie Moya; Kazuhiro Sakamaki; Benjamin M. Mason; Lotte Huisman; Sylvain Foret; Yvonne Weiss; Tara E. Bull; Kentaro Tomii; Kenichiro Imai; David C. Hayward; Eldon E. Ball; David J. Miller

  BMC GENOMICS, Jan. 2016, Peer-reviewed

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• Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change

  Kazuhiro Sakamaki; Naoyuki Iwabe; Hiroaki Iwata; Kenichiro Imai; Chiyo Takagi; Kumiko Chiba; Chisa Shukunami; Kentaro Tomii; Naoto Ueno

  Biochemistry and Biophysics Reports, 01 Sep. 2015, Peer-reviewed

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• Evolutionary analyses of caspase-8 and its paralogs: Deep origins of the apoptotic signaling pathways

  Kazuhiro Sakamaki; Kenichiro Imai; Kentaro Tomii; David J. Miller

  BIOESSAYS, Jul. 2015, Peer-reviewed, Invited

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• The Apoptotic Initiator Caspase-8: Its Functional Ubiquity and Genetic Diversity during Animal Evolution

  Kazuhiro Sakamaki; Kouhei Shimizu; Hiroaki Iwata; Kenichiro Imai; Yutaka Satou; Noriko Funayama; Masami Nozaki; Mamiko Yajima; Osamu Nishimura; Mayura Higuchi; Kumiko Chiba; Michi Yoshimoto; Haruna Kimura; Andrew Y. Gracey; Takashi Shimizu; Kentaro Tomii; Osamu Gotoh; Koji Akasaka; Tatsuya Sawasaki; David J. Miller

  MOLECULAR BIOLOGY AND EVOLUTION, Dec. 2014, Peer-reviewed

  
• Transgenic Xenopus laevis for live imaging in cell and developmental biology

  Chiyo Takagi; Kazuhiro Sakamaki; Hitoshi Morita; Yusuke Hara; Makoto Suzuki; Noriyuki Kinoshita; Naoto Ueno

  DEVELOPMENT GROWTH & DIFFERENTIATION, May 2013, Peer-reviewed

  
• In Vivo Imaging of Hierarchical Spatiotemporal Activation of Caspase-8 during Apoptosis

  Katsuya Kominami; Takeharu Nagai; Tatsuya Sawasaki; Yuki Tsujimura; Kenta Yashima; Yasuhiro Sunaga; Masateru Tsuchimochi; Jun Nishimura; Kumiko Chiba; Jun Nakabayashi; Koji Koyamada; Yaeta Endo; Hideo Yokota; Atsushi Miyawaki; Noboru Manabe; Kazuhiro Sakamaki

  PLOS ONE, Nov. 2012, Peer-reviewed

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• Multiple functions of FADD in apoptosis, NF-kappa B-related signaling, and heart development in Xenopus embryos

  Kazuhiro Sakamaki; Chiyo Takagi; Atsushi Kitayama; Tomoko Kurata; Takamasa S. Yamamoto; Kumiko Chiba; Katsuya Kominami; Sang-Kee Jung; Katsuya Okawa; Masami Nozaki; Hiroshi Y. Kubota; Naoto Ueno

  GENES TO CELLS, Nov. 2012, Peer-reviewed

  
• The molecular mechanism of apoptosis upon caspase-8 activation: Quantitative experimental validation of a mathematical model

  Katsuya Kominami; Jun Nakabayashi; Takeharu Nagai; Yuki Tsujimura; Kumiko Chiba; Haruna Kimura; Atsushi Miyawaki; Tatsuya Sawasaki; Hideo Yokota; Noboru Manabe; Kazuhiro Sakamaki

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, Oct. 2012, Peer-reviewed

  
• Caspase-8 cleavage of the interleukin-21 (IL-21) receptor is a negative feedback regulator of IL-21 signaling

  Tatsuya Akagi; Kouhei Shimizu; Shoukichi Takahama; Takahiro Iwasaki; Kazuhiro Sakamaki; Yaeta Endo; Tatsuya Sawasaki

  FEBS LETTERS, Jun. 2011, Peer-reviewed

  
• Caspases: Evolutionary aspects of their functions in vertebrates

  K. Sakamaki; Y. Satou

  Journal of Fish Biology, Mar. 2009, Peer-reviewed

  
• Conserved function of caspase-8 in apoptosis during bony fish evolution

  Shin-ichi Sakata; YiLin Yan; Yutaka Satou; Akihiro Momoi; Phuong Ngo-Hazelett; Masami Nozaki; Makoto Furutani-Seiki; John H. Postlethwait; Shin Yonehara; Kazuhiro Sakamaki

  GENE, Jul. 2007, Peer-reviewed

  
• The evolutionary conservation of the core components necessary for the extrinsic apoptotic signaling pathway, in Medaka fish

  Kazuhiro Sakamaki; Masami Nozaki; Katsuya Kominami; Yutaka Satou

  BMC GENOMICS, Jun. 2007, Peer-reviewed

  
• The initiator caspase, caspase-10 beta, and the BH-3-only molecule, Bid, demonstrate evolutionary conservation in Xenopus of their pro-apoptotic activities in the extrinsic and intrinsic pathways

  K Kominami; C Takagi; T Kurata; A Kitayama; M Nozaki; T Sawasaki; K Kuida; Y Endo; N Manabe; N Ueno; K Sakamaki

  GENES TO CELLS, Jul. 2006, Peer-reviewed

  
• Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p35

  N Yajima; S Yamada; T Morisaki; S Toyokuni; S Yonehara; K Sakamaki

  TRANSGENIC RESEARCH, Oct. 2005, Peer-reviewed

  
• Transgenic frogs expressing the highly fluorescent protein venus under the control of a strong mammalian promoter suitable for monitoring living cells

  K Sakamaki; C Takagi; J Yoshino; H Yokota; S Nakamura; K Kominami; A Hyodo; K Takamune; M Yuge; N Ueno

  DEVELOPMENTAL DYNAMICS, Jun. 2005, Peer-reviewed

  
• The adaptor molecule FADD from Xenopus laevis demonstrates evolutionary conservation of its pro-apoptotic activity

  K Sakamaki; C Takagi; K Kominami; S Sakata; Y Yaoita; HY Kubota; M Nozaki; S Yonehara; N Ueno

  GENES TO CELLS, Dec. 2004, Peer-reviewed

  
• Regulation of endothelial cell death and its role in angiogenesis and vascular regression

  K Sakamaki

  CURRENT NEUROVASCULAR RESEARCH, Oct. 2004, Peer-reviewed

  
• Age-related thymic involution is mediated by Fas on thymic epithelial cells

  N Yajima; K Sakamaki; S Yonehara

  INTERNATIONAL IMMUNOLOGY, Jul. 2004, Peer-reviewed

  
• Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia

  Noboru Manabe; Naoke Inoue; Miki Sugimoto; Hajime Miyamoto; Takashi Miyano; Kazuhiro Sakamaki

  The Ovary: Second Edition, 18 Dec. 2003, Peer-reviewed

  
• Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient W-v/W-v mutant mice

  S Sakata; S Sakamaki; K Watanabe; N Nakamura; S Toyokuni; Y Nishimune; C Mori; S Yonehara

  CELL DEATH AND DIFFERENTIATION, Jun. 2003, Peer-reviewed

  
• Physiological and pathological cell deaths in the reproductive organs

  K Sakamaki

  CELL STRUCTURE AND FUNCTION, Feb. 2003, Peer-reviewed

  
• Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart

  K Sakamaki; T Inoue; M Asano; K Sudo; H Kazama; J Sakagami; S Sakata; M Ozaki; S Nakamura; S Toyokuni; N Osumi; Y Iwakura; S Yonehara

  CELL DEATH AND DIFFERENTIATION, Nov. 2002, Peer-reviewed

  
• 細胞死（アポトーシス）のシグナル伝達機構と生体における役割:アポトーシス実行因子カスパーゼ8を中心に.

  酒巻和弘

  岡山実験動物研究会報,19:3-7, 2002

  
• The evolutionary conservation of the mammalian peroxidase genes

  K Sakamaki; T Ueda; S Nagata

  CYTOGENETIC AND GENOME RESEARCH, 2002, Peer-reviewed

  
• The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17

  K Sakamaki; N Kanda; T Ueda; E Aikawa; S Nagata

  CYTOGENETICS AND CELL GENETICS, 2000, Peer-reviewed

  
• シグナル伝達研究の新しい局面注目される空間的・時間的制御機構 シグナル伝達分子の新展開 アポトーシスのシグナル伝達機構

  酒巻和弘; 米原伸

  実験医学, Sep. 1998, Invited

  
• Molecular cloning and characterization of mouse caspase-8

  Kazuhiro Sakamaki; Shin-Ichi Tsukumo; Shin Yonehara

  European Journal of Biochemistry, 15 Apr. 1998, Peer-reviewed

  
• Involvement of Fas antigen in ovarian follicular atresia and luteolysis

  K Sakamaki; H Yoshida; Y Nishimura; SI Nishikawa; N Manabe; S Yonehara

  MOLECULAR REPRODUCTION AND DEVELOPMENT, May 1997, Peer-reviewed

  
• Fas and apoptosis.

  酒巻和弘; 西村慶子; 李慶権; 今居譲; 米原伸

  放射線生物研究 (総説), 1997, Peer-reviewed

  
• Molecular cloning and characterization of the chromosomal gene for human lactoperoxidase

  Tadashi Ueda; Kazuhiro Sakamaki; Tetsuo Kuroki; Ikuya Yano; Shigekazu Nagata

  European Journal of Biochemistry, 1997, Peer-reviewed

  
• The Fas System in Mammalian Reproductive Organs

  SAKAMAKI Kazuhiro; YONEHARA Shin

  The Japanese journal of animal reproduction, 1996

  
• Signal transmission of granulosa cell apoptosis in the atretic antral follicles in the pig ovaries

  Manabe N; Myoumoto A; Kimura Y; Imai Y; Sakamaki K; Okamura Y; Fukumoto M; Sugimoto M; Miyamoto H

  J Reprod Develop, 1996, Peer-reviewed

  
• SERUM ALLEVIATES THE REQUIREMENT OF THE GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF)-INDUCED RAS ACTIVATION FOR PROLIFERATION OF BAF3 CELLS

  K SAKAMAKI; S YONEHARA

  FEBS LETTERS, Oct. 1994, Peer-reviewed

  
• SIGNAL-TRANSDUCTION BY THE HIGH-AFFINITY GM-CSF RECEPTOR - 2 DISTINCT CYTOPLASMIC REGIONS OF THE COMMON BETA-SUBUNIT RESPONSIBLE FOR DIFFERENT SIGNALING

  N SATO; K SAKAMAKI; N TERADA; K ARAI; A MIYAJIMA

  EMBO JOURNAL, Nov. 1993, Peer-reviewed

  
• LIGAND-DEPENDENT ACTIVATION OF CHIMERIC RECEPTORS WITH THE CYTOPLASMIC DOMAIN OF THE INTERLEUKIN-3 RECEPTOR BETA-SUBUNIT (BETA-IL3)

  K SAKAMAKI; HM WANG; MIYAJIMA, I; T KITAMURA; K TODOKORO; N HARADA; A MIYAJIMA

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 1993, Peer-reviewed

  
• CRITICAL CYTOPLASMIC DOMAINS OF THE COMMON BETA-SUBUNIT OF THE HUMAN GM-CSF, IL-3 AND IL-5 RECEPTORS FOR GROWTH SIGNAL TRANSDUCTION AND TYROSINE PHOSPHORYLATION

  K SAKAMAKI; MIYAJIMA, I; T KITAMURA; A MIYAJIMA

  EMBO JOURNAL, Oct. 1992, Peer-reviewed

  
• RECONSTITUTION OF FUNCTIONAL RECEPTORS FOR HUMAN GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) - EVIDENCE THAT THE PROTEIN ENCODED BY THE AIC2B CDNA IS A SUBUNIT OF THE MURINE GM-CSF RECEPTOR

  T KITAMURA; K HAYASHIDA; K SAKAMAKI; T YOKOTA; K ARAI; A MIYAJIMA

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jun. 1991, Peer-reviewed

  
• IDENTIFICATION OF PEANUT AGGLUTININ RECEPTORS ON MOUSE TESTICULAR GERM-CELLS

  K SAKAMAKI; K SAWADA; U KOSHIMIZU; Y NISHIMUNE

  BIOLOGY OF REPRODUCTION, Dec. 1989, Peer-reviewed

  
• MOLECULAR-CLONING AND CHARACTERIZATION OF A CHROMOSOMAL GENE FOR HUMAN EOSINOPHIL PEROXIDASE

  K SAKAMAKI; M TOMONAGA; K TSUKUI; S NAGATA

  JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 1989, Peer-reviewed

  
• IDENTIFICATION OF THE SPECIFIC PROTEINS ASSOCIATED WITH DIFFERENTIATION OF SPERMATOGONIA IN MICE BY TWO-DIMENSIONAL GEL-ELECTROPHORESIS

  K SAKAMAKI; K SAWADA; Y NISHIMUNE

  BIOLOGY OF REPRODUCTION, Nov. 1987, Peer-reviewed

  
• Effect of duration of cryptorchidism on ability of mouse germ cells to regenerate and differentiate

  Y. Nishimune; M. Maekawa; K. Sakamaki; T. Haneji

  Systems Biology in Reproductive Medicine, 1986, Peer-reviewed

  
• Effects of steel mutation on spermatogenesis stimulated by fetuin

  Y. Nishimune; T. Haneji; M. Maekawa; K. Sakamaki; Y. Kitamura

  Systems Biology in Reproductive Medicine, 1985, Peer-reviewed

  

Misc.

• 細胞死(アポトーシス)に伴う細胞形態の時系列的変動の解析

  酒巻 和弘; 河村 拓馬; 坂本 尚久; 小山田 耕二

  バイオイメージング, 30 Oct. 2008

  
• 細胞死に伴う小胞形成の時系列的変動の解析

  酒巻 和弘; 坂本 尚久; 河村 拓馬; 千場 久美子; 澤崎 達也; 小山田 耕二

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2010

  
• Spatiotemporal Analysis of Morphological Changes in Cell Death Using Multiple Volume Visualization

  KAWAMURA Takuma; SAKAMOTO Naohisa; KIOKA Miki; SAKAMAKI Kazuhiro; KOYAMADA Koji

  可視化情報学会誌. Suppl. = Journal of the Visualization Society of Japan, 15 Sep. 2008

  
• THE IL-3 AND GM-CSF RECEPTORS AND SIGNAL-TRANSDUCTION

  A MIYAJIMA; A MUI; N SATO; K SAKAMAKI; T KINOSHITA; T KITAMURA; MIYAJIIMA, I; T IWAMOTO; T OGOROCHI; D GORMAN; S WATANABE; K ARAI; M ICHIHARA; M TAKAGI; T HARA

  JOURNAL OF CELLULAR BIOCHEMISTRY, Jan. 1994

  
• イメージングによる1細胞でのカスパーゼ8活性化機構の解析

  小南 勝也; 永井 健治; 中林 潤; 大島 典子; 高田 元; 眞鍋 昇; 宮脇 敦史; 酒巻 和弘

  バイオイメージング, 26 Sep. 2005

  
• Involvement of a novel mouse CED-4 homologue FLASH in Fasmediated apoptosis through binding to caspase-8

  IMAI Yuzuru; KIMURA Takaharu; YAJIMA Nobuyuki; MURAKAMI Akira; SAKAMAKI Kazuhiro; YONEHARA Shin

  日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

  
• Molecular mechanism of Ras dependent protection against Fasinduced apoptosis in Balb/c3T3 cells

  KAZAMA Hirotaka; LEE Kyung-Kwon; SAKAMAKI Kazuhiro; YONEHARA Shin

  日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

  
• Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage

  SAKAMAKI Kazuhiro; ISHII Takahiro M; SAKATA Toshiya; TAKEMOTO Kiwamu; TAKAGI Chiyo; TAKEUCHI Ayako; MORISHITA Ryo; TAKAHASHI Hirotaka; NOZAWA Akira; SHINODA Hajime; CHIBA Kumiko; SUGIMOTO Haruyo; SAITO Akiko; TAMATE Shuhei; SATOU Yutaka; JUNG Sang‐Kee; MATSUOKA Satoshi; KOYAMADA Koji; SAWASAKI Tatsuya; NAGAI Takeharu; NAGAI Takeharu; UENO Naoto

  Biochimica et Biophysica Acta, Nov. 2016

  
• New evolutionary perspectives on an essential initiator of apoptotic cell death, caspase-8, and its paralogs

  Kazuhiro SAKAMAKI

  The 20th Evolutionary Biology Meeting, Sep. 2016

  
• Ubiquity and diversity of caspase-8 evolution in metazoan

  K. Sakamaki; H. Iwata; Y. Satou; N. Funayama; M. Nozaki; D.J. Miller

  第37回日本分子生物学会年会, Nov. 2014

  
• In Vivo Imaging of Spatiotemporal Activation of Caspase-8 during Apoptosis

  K. Sakamaki; Y. Tsujimura; K. Yashima; Y. Sunaga; J. Nishimura; K. Kominami; K. Koyamada; J. Nakabayashi; H. Yokota

  第36回日本分子生物学会年会, Dec. 2013

  
• 細胞死（アポトーシス）の分子機構とその生理的役割

  酒巻和弘

  日本比較免疫学会第25回学術集会シンポジウム, Aug. 2013

  
• The viral FLIP E8 inhibits multilineage differentiation from mesenchymal stem cells, resulting in bone malformation, lipoatrophy and muscular atrophy in transgenic mice

  N. Yajima; M. Honda; Y. Okazaki; T. Toriumi; K. Chiba; S. Yamada; S. Yonehara; S. Toyokuni; Y. Arai; K. Sakamaki

  第35回日本分子生物学会年会, Dec. 2012

  
• Analysis of programmed cell death in Xenoupus embryos using a FRET-based caspase biosenso

  K. Sakamaki; M. Suzuki; C. Takagi; Y. Hara; K. Kominami; K. Chiba; H.Y. Kubota; N. Ueno

  第45回日本発生生物学会, May 2012

  
• c-FLIP, an apoptosis-regulatory protein specific to the vertebrate lineage

  K. Sakamaki; K. Chiba; Chiyo Takagi; H. Iwata; M. Nozaki; C. Shukunami; O. Gotoh; N. Ueno

  第34回日本分子生物学会年会, Dec. 2011

  
• Involvement of an apoptosis-inducing adaptor, FADD in embryonic development of Xenopus laevis

  SAKAMAKI Kazuhiro; TAKAGI Chiyo; KIMURA Haruna; JUNG Sang‐Kee; OKAWA Katsuya; UENO Naoto

  Program Abstr Book Annu Meet Jpn Soc Dev Biol, 2010

  
• 細胞死シグナル伝達系の細胞内ダイナミクス: リアルタイムイメージングによる実測データとモデルとのフィッティング

  中林潤; 佐々木顕; 酒巻和弘; 小南勝也

  第19回日本数理生物学会年会シンポジウム, Sep. 2009

  
• REGULATION OF FOLLICULAR ATRESIA BY CELL DEATH LIGAND AND RECEPTOR SYSTEM

  N. MANABE; F. MATSUDA-MINEHATA; Y. GOTO; A. MAEDA; Y. CHENG; H. GONDA; K. WONGPANIT; H. JIN; J. LI; K. SAKAMAKI; T. MIYANO

  The 4th Annual Conference of the Asian Reproductive Biotechnology Society, “Reproductive Biotechnology, Stem Cells and Regenerative Medicine”, Nov. 2007

  
• Cell death ligand and receptor dependent regulatory mechanisms of follicle selection in porcine ovaries

  Noboru manabe; Akihisa Maeda; Yasufumi Goto; Fuko Minehata; Naoko Inoue; Yuan Cheng; Huazi Jin; Kannika Wongpanit; Shoma Nakagawa; Junyou Li; Takashi miyano; Kazuhiro Sakamaki

  Morphology, 2007

  
• カスパーゼ8新規標的分子THIK‐1の解析

  酒巻和弘; 竹本研; 澤崎達也; 高田元; 森下了; 佐藤ゆたか; 小南勝也; 大島典子; 眞鍋昇; 遠藤弥重太; 永井健治; 石井孝広

  生化学, 2007

  
• Application of transgenic technology: a challenge to detect dynamic processes in living animals

  K. Sakamaki; C. Takagi; C. Waldner; T. Kawasaki; K. Takamune; G.U. Ryffel; N. Ueno

  The 11th International Xenopus Meeting, Sep. 2006

  
• Dual-FRET-based imaging of both initiator and effector caspase activation in the single cells

  K. Kominami; T. Nagai; T. Sawasaki; N. Oshima; M. Tsuchimochi; G. Takata; J. Nakabayashi; N. Manabe; Y. Endo; A. Miyawaki; K. Sakamaki

  The 20th IUBMB International Congress of Biochemistry and Molecular Biology, Jun. 2006

  
• Dual-FRET system –カスパーゼ8活性とカスパーゼ3活性を同時にイメージングする–

  小南勝也; 永井健治; 中林潤; 大島典子; 高田元; 眞鍋昇; 宮脇敦史; 酒巻和弘

  第28回日本分子生物学会年会ワークショップ, Dec. 2005

  
• 進化に伴ったアポトーシス実行因子の多様化と細胞死の普遍性の意義

  酒巻和弘

  第７回日本進化学会シンポジウム, Aug. 2005

  
• Oocyte survival and follicular development in Fas-knockout and KIT-deficient double mutant mice

  M. Moniruzzaman; K. Sakamaki; Y. Akazawa; T. Miyano

  REPRODUCTION FERTILITY AND DEVELOPMENT, 2005

  
• Growth of oocytes in KIT-deficient Fas-knockout mice

  MONIRUZZAMAN M; SAKAMAKI K; AKAZAWA Y; LEE J; MIYANO T

  Kobe University the 21st Century COE Program Symposium "Signal Transduction in Gametogenesis and Fertilization", Nov. 2004

  
• トランスジェニックカエルの樹立とその応用について

  酒巻和弘

  第75回日本動物学会大会共催シンポジウム, Sep. 2004

  
• Apoptotic signaling machinery in the reproductive organs

  K. Sakamaki; K. Kominami; S. Sakata; N. Manabe; S. Yonehara

  The 2nd Pacific Conference on Reproductive Biology and Environmental Sciences, Oct. 2002

  
• アポトーシス誘導シグナル伝達におけるカスパーゼ8の役割

  酒巻和弘; 米原伸

  第23回日本分子生物学会年会ワークショップ, Dec. 2000

  
• アポトーシス実行因子カスパーゼ8の生体における役割

  酒巻和弘

  第73回日本生化学会大会シンポジウム, Oct. 2000

  
• Functional analysis of Caspase-8 with Caspase-8-deficient mouse

  SAKAMAKI Kazuhiro; ASANO Masahide; SAKATA Shin-ichi; TOYOKUNI Shinya; IWAKURA Yoichiro; YONEHARA Shin

  日本分子生物学会年会プログラム・講演要旨集, 01 Dec. 1998

  
• Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa. (vol 273, pg 19160, 1998)

  KK Lee; M Murakawa; S Takahashi; S Tsubuki; S Kawashima; K Sakamaki; S Yonehara

  JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 1998

  
• 生殖組織におけるアポトーシスとFas抗原

  酒巻和弘; 米原伸

  第89回日本繁殖生物学会シンポジウム, Oct. 1996

  
• DELETION ANALYSIS OF THE COMMON BETA SUBUNIT OF THE GM-CSF, IL-3, AND IL-5 RECEPTORS

  N SATO; K SAKAMAKI; MIYAJIMA, I; T KITAMURA; K ARAI; A MIYAJIMA

  JOURNAL OF CELLULAR BIOCHEMISTRY, Jan. 1993

  
• FUNCTIONAL DIFFERENCES BETWEEN ALPHA-SUBUNITS OF THE HUMAN IL-3 AND GM-CSF RECEPTORS

  T KITAMURA; K SAKAMAKI; A MIYAJIMA

  JOURNAL OF CELLULAR BIOCHEMISTRY, Jan. 1993

  
• SIGNAL TRANSDUCTION MEDIATED BY THE HUMAN GM-CSF RECEPTOR IN MURINE FACTOR-DEPENDENT CELL-LINES

  K SAKAMAKI; T KITAMURA; K HAYASHIDA; A MIYAJIMA

  FASEB JOURNAL, Mar. 1991

  
• ANALYSIS OF PGC SPECIFIC PROTEINS IN MOUSE

  K SAWADA; K SAKAMAKI; Y NISHIMUNE

  DEVELOPMENT GROWTH & DIFFERENTIATION, Aug. 1988

  
• IDENTIFICATION OF PEANUT AGGLUTININ RECEPTORS ON MOUSE TESTICULAR GERM-CELLS

  K SAKAMAKI; K SAWADA; Y NISHIMUNE

  CELL STRUCTURE AND FUNCTION, Dec. 1987

  
• THE EFFECT OF W MUTATION ON SPERMATOGENESIS

  K SAWADA; K SAKAMAKI; Y NISHIMUNE

  DEVELOPMENT GROWTH & DIFFERENTIATION, Aug. 1987

  

Presentations

• The evolutionarily conserved apoptotic machinery in corals.

  Kazuhiro Sakamaki

  "Origins and Function of the Animal Metaorganism", An Australian Academy of Science Boden Research Conference, 13 Mar. 2018, The Great Barrier Reef Foundation, the Ian Potter Foundation and the ARC COE for Coral Reef Studies, Invited

  
• アポトーシス実行因子caspase-8 〜分子進化学的解析から見えてきたこと〜

  酒巻 和弘

  神戸大学理学研究科セミナー, 30 Sep. 2016, 神戸大学理学研究科

  
• The origin and evolutionary divergence of the apoptotic initiator caspase-8

  SAKAMAKI Kazuhiro

  第18回京都大学生命科学研究科シンポジウム, 08 Jul. 2016, 京都大学生命科学研究科

  
• アポトーシス実行因子カスパーゼ8の普遍性と進化的変遷

  酒巻 和弘

  創薬等支援技術基盤プラットフォーム(PDIS)ワークショップ ～実験とバイオインフォマティクスの協奏による構造生命科学～, 18 Dec. 2014, 産総研・東京大学合同

  
• 細胞死シグナル伝達経路の階層的・時空間的解析

  酒巻和弘

  第16回京都大学生命科学研究科シンポジウム, 01 Jul. 2014, 京都大学生命科学研究科

  
• アポトーシスの分子機構とその生物学的意義について 〜アポトーシスのシグナル伝達とカスパーゼ活性化のメカニズム〜

  酒巻和弘

  愛媛大学生物学科セミナー, 16 May 2014, 愛媛大学理学部

  
• アポトーシス実行因子カスパーゼ8の活性化機構とその特異性

  酒巻和弘

  産業技術総合研究所生命情報工学研究センター第４回セミナー, 05 Sep. 2013, 産業技術総合研究所生命情報工学研究センター

  
• 細胞死シグナルの可視化と形態形成について

  酒巻和弘

  第14回京都大学生命科学研究科シンポジウム, 11 Jul. 2012, 京都大学生命科学研究科

  
• 細胞死シグナルの可視化

  IN Cell User’s Day 2009, 09 Oct. 2009, GEヘルスケア・ジャパン株式会社主催

  
• ３次元内部構造顕微鏡を用いた移植細胞の３次元観察 -細胞死誘導シグナルの数値化ならびに細胞動態の３次元解析-

  理研シンポジウム「生体形状情報の数値化及びデータベース構築」, 18 Dec. 2008, 理化学研究所

  
• 細胞死シグナルのイメージングと伝達経路のモデル化

  酒巻和弘

  第6回鹿児島大学バイオインフォマティクス講演会, 08 Mar. 2007, バイオインフォマティクス研究会, Invited

  
• 細胞死（アポトーシス）のシグナル伝達機構と生体における役割

  酒巻和弘

  第42回岡山実験動物研究会, 30 Nov. 2001, 岡山実験動物研究会, Invited

  
• アポトーシス実行因子と形態形成

  酒巻和弘

  京都大学ウイルス研究所コロキウム, Feb. 1999, 京都大学ウイルス研究所

  
• ストレスとアポトーシス

  酒巻和弘; 米原伸

  異分野研究者交流フォーラム「医療と科学技術-ストレスを科学する-」, Feb. 1997, JST

  

Books and Other Publications

• 反応する細胞 シグナル伝達「京大発！ フロンティア生命科学」

  酒巻和弘, ９章

  講談社サイエンティフィク（京都大学生命科学研究科 編）, Mar. 2018, Not refereed

  
• Follicle selection in mammalian ovaries: regulatory mechanisms of granulosa cell apoptosis during follicular atresia.

  Manabe, N; Inoue, N; Miyano, T; Sakamaki, K; Sugimoto, M; Miyamoto, H

  The Ovary 2e, Academic Press, pp.369-385, 2003, Not refereed

  
• デスレセプターを介したアポトーシス誘導シグナル

  酒巻和弘

  実験医学 18(15):pp.67-72、羊土社, 2000, Not refereed

  
• Involvement of the Fas and Fas ligand system in apoptosis of the reproductive organs.

  Sakamaki, K; Yonehara, S

  Reproductive Biology Update: Novel tools for assessment of environmental toxicity. Shoukadoh Booksellers Co., pp.3-21, 1998, Not refereed

  
• アポトーシスのシグナル伝達機構

  酒巻和弘; 米原伸

  実験医学「シグナル伝達研究の新しい局面」 16(14):pp.146-152 羊土社, 1998, Not refereed

  
• 生殖器官と細胞死

  酒巻和弘

  現代科学 増刊35:pp.137-143、東京化学同人, 1997, Not refereed

  
• TNFレセプターファミリー

  酒巻和弘; 米原伸

  実験医学別冊:「BioScience用語ライブラリー・免疫」pp.160-161 羊土社, 1995, Not refereed

  
• Fas/Fasリガンド

  酒巻和弘; 米原伸, Joint work

  実験医学別冊「BioScience用語ライブラリー・サイトカイン/増殖因子」:pp.170-171 羊土社, 1995, Not refereed

  
• Function of the common beta subunit of the GM-CSF/IL-3/IL-5 receptors

  Mui, A.L-F; Muto, A; Sakamaki, K; Sato, N; Kinoshita, T; Watanabe, S; Yokota, T; Arai, K; Miyajima, A

  Plenum Press, New York, USA, Adv. Exp. Med. Biol. 365:pp.217-223, 1994, Not refereed

  
• Signal transduction by the granulocyte-macrophage colony stimulating factor and interleukin-3 (IL-3) receptors.

  Sato, N; Sakamaki, K; Mui; A.L-F; Kinoshita, T; Watanabe, S; Arai, K; Miyajima, A

  Horizon in cytokine research (Mochida Memorial Foundation for Medical and Pharmaceutical Research) pp.61-69, 1993, Not refereed

  
• サイトカインレセプターとシグナル伝達

  酒巻和弘; 宮島篤

  Medical Immunology 24(1):pp.47-54、国際医書出版, 1992, Not refereed

  
• IL-3レセプターとGM-CSFレセプター

  北村俊雄; 酒巻和弘; 新井賢一; 宮島篤

  実験医学 10(3):pp.25-30 羊土社, 1992, Not refereed

  
• 造血因子とレセプター

  酒巻和弘; 宮島篤; 新井賢一

  Biotherapy 4(12):pp.1850-1860 癌と化学療法社, 1990, Not refereed

  
• 生化学辞典 第２版

  酒巻和弘, Contributor

  東京化学同人, 1990, Not refereed

  

Works

• 両生類を用いた細胞死に関する研究

  From 2001

  
• Research on apoptosis in amphibian

  From 2001

  

External funds: Kakenhi

• Structural analysis of cFLIP as an iron-binding protein and elucidation of a new physiological function

  Grant-in-Aid for Scientific Research (C)

  Basic Section 38030:Applied biochemistry-related

  Kyoto University

  酒巻 和弘

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  鉄結合タンパク質;Fenton反応;鉄硫黄タンパク質;フェロプトーシス;分子進化;偽プロテアーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K05380/
• Comprehensive identification of caspase-dependent signal transduction pathway using cell-free protein array

  Grant-in-Aid for Scientific Research (B)

  Ehime University

  Tatsuya SAWASAKI

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  蛋白質ネットワーク;カスパーゼ;無細胞タンパク質合成;プロテオリシス;タンパク質;切断;プロテインアレイ;コムギ胚芽;AlphaScreen;Alpha Screen;無細胞蛋白質合成系;カスパーゼ3;蛋白質代謝;細胞死;プロテアーゼ;蛋白ライブラリー;プロテインカイネース;細胞内シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22310127/
• In vivo imaging of embryonic cell death in the new model animal and its molecular analysis

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Kazuhiro SAKAMAKI

  From 01 Apr. 2009, To 31 Mar. 2013, Project Closed

  発生遺伝;細胞死;胚発生;アフリカツメガエル;カスパーゼ;アポトーシス;トランスジェニックカエル;モニター分子;可視化;イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21570223/
• 比較ゲノム情報に基づくアポトーシス実行因子の普遍性と多様性の解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  酒巻 和弘

  From 01 Apr. 2008, To 31 Mar. 2010, Project Closed

  細胞死;分子系統;タンパク質構造;プロテアーゼ;カスパーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20017016/
• Study for the cell lineage and tissue specificity in embryonic cells using transgenic Xenopus frogs

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Kazuhiro SAKAMAKI

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  トランスジェニックカエル;GFP;Cre;DsRed;3次元画像, Transgenic;Xenopus;fluorescent protein;Cre;loxP

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17570176/
• Studies on In Vivo gene modification by injection of TAT-Cre fusion protein and establishment of the practical technique.

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Shuichi YAMADA

  From 01 Apr. 2003, To 31 Mar. 2005, Project Closed

  HIV;TAT;Cre;LoxP;recombination;遺伝子組み換え;コンデショナル;トランスジェニック;マウス, HIV;TAT;Cre;LoxP;recombination

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15300140/
• Fasを介するアポトーシスシグナル抑制による細胞がん化分子機構の解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  米原 伸

  From 01 Apr. 2003, To 31 Mar. 2004, Project Closed

  遺伝子;癌;細胞・組織;シグナル伝達

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15024234/
• 遺伝子欠損マウスを用いたアポトーシス抑制に伴う発癌機構の解明

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  酒巻 和弘

  From 01 Apr. 2002, To 31 Mar. 2003, Project Closed

  カスパーゼ;アポトーシス;デスレセプター;ノックアウトマウス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14028033/
• 哺乳類卵胞の選択的死滅制御機構とその人為支配による潜在的卵巣卵の利用

  Grant-in-Aid for Creative Scientific Research

  The University of Tokyo;Kyoto University

  眞鍋 昇

  From 01 Apr. 2001, To 31 Mar. 2006, Project Closed

  哺乳類;卵巣;卵胞;選択的死滅;アポトーシス;細胞死受容体;細胞内シグナル伝達阻害因子;異種移植;カスパーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13GS0008/
• アポトーシス実行因子カスパーゼ8のがん抑制因子としての機能解析

  Grant-in-Aid for Scientific Research on Priority Areas (C)

  Biological Sciences

  Kyoto University

  酒巻 和弘

  From 01 Apr. 2001, To 31 Mar. 2002, Project Closed

  カスパーゼ;アポトーシス;デスレセプター;細胞死;ミトコンドリア;キメラマウス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13216051/
• デスレセプターを介したアポトーシス誘導に関与するカスパーゼの機能解析

  Grant-in-Aid for Scientific Research on Priority Areas (C)

  Biological Sciences

  Kyoto University

  酒巻 和弘

  From 01 Apr. 2000, To 31 Mar. 2001, Project Closed

  カスパーゼ;アポトーシス;デスレセプター;Fas;細胞死

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12215070/
• アポトーシスの情報伝達制御

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  米原 伸

  From 01 Apr. 2000, To 31 Mar. 2003, Project Closed

  アポトーシス;Fas;Tax;SR-PSOX;CSCL16;TRAF6;CD40;NFκB;TIFA;caspsae-8;FADD;自己免疫疾患;リンパ球;TRAF

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12051218/
• Analysis of intracellular regulatory signaling for apoptosis induction

  Grant-in-Aid for Scientific Research (B).

  KYOTO UNIVERSITY

  Shin YONEHARA

  From 01 Apr. 1999, To 31 Mar. 2001, Project Closed

  Fas;細胞死;アポトーシス;Ras;マップキナーゼ;caspase;FLASH;Tax;アデノウイルスE1B, Fas;cell death;apoptosis;Ras;MAP kinase;caspase;FLASH;Tax

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11480208/
• Analysis of the structure and interaction of apoptotic signaling molecules via Fas

  Grant-in-Aid for Scientific Research (C)

  KYOTO UNIVERSITY

  Kazuhiro SAKAMAKI

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  アポトーシス;デス-エフェクター-ドメイン;caspase-8;FADD;MC159;デス・エフェクター・ドメイン;デス-エフェクター・ドメイン;Caspase-8, apoptosis;Death Effector Domain;Caspase-8;FADD;MC159

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10680606/
• Fasを介するアポトーシスの分子機構と生理機能の解析

  Grant-in-Aid for Scientific Research on Priority Areas (A)

  Kyoto University

  米原 伸

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  Fas;細胞死;アポトーシス;Ras;マップキナーゼ;caspase;FLASH;マデノウイルスE1B;RAS;カスパーゼ;MST;カスパーゼ8

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10153225/
• In vivo function of Fas antigen in the immune system

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Shin YONEHARA

  From 01 Apr. 1995, To 31 Mar. 1997, Project Closed

  Fas抗原(Fas);アポトーシス;トランスジェニックマウス;gldマウス;自己免疫疾患;リウマチ様関節炎;糸球体腎炎;胸腺;lprマウス;劇症肝炎, Fas Antigen (Fas);Apoptosis;Transgenic mouse;gld mouse;Autoimmune disease;Rheumatold arthritis;glomerulonephritis

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07457086/
• 細胞および生体レベルにおけるFas抗原の作用機構

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  米原 伸

  From 01 Apr. 1995, To 31 Mar. 1998, Project Closed

  アポトーシス;Fas;プロテインキナーゼ;MST;ras;カスパーゼ;Fas抗原(Fas);HTLV-1(成人T細胞白血病ウイルス);Tax;卵巣;gldマウス;lymphopadenopathy

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07274233/
• Proliferation and differentiation of granulocytes

  Grant-in-Aid for General Scientific Research (B)

  Osaka Bioscience Institute

  Shigekazu NAGATA

  From 01 Apr. 1987, To 31 Mar. 1989, Project Closed

  顆粒球コロニー刺激因子;ミエロペルオキシダーゼ;好酸球ペルオキシダーゼ;骨髄性白血病細胞;増殖・分化因子;血球の増殖と分化;受容体;ミエルペルオキシダーゼ;好酸球;多能性幹細胞;遺伝子工学;細胞の増殖と分化, Haemopoiesis;Granulocyte colony-stimulating factor;Myeloid leukemia;Proliferaton and differentiaton;Neutrophil

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-62480131/

External funds: others

• アポトーシス実行因子カスパーゼの血管形成における役割と作用機序の解明並びに血管新生抑制化の試み

  医薬資源研究助成金

  From 2004, To 2004

  酒巻和弘
• 遺伝子組み換えツメガエルを用いた精子保存方法の開発

  成茂動物科学振興基金

  From 2006, To 2006

  酒巻和弘
• 細胞死における小胞形成の時空間ダイナミクスの可視化と分子機構の解明

  京都大学コアステージバックアップ

  From Jun. 2013, To Mar. 2014

  酒巻和弘
• 間葉系幹細胞から骨や筋肉への組織形成を制御するE8標的分子の同定と分化誘導機構の解明

  成長科学協会研究助成金

  From Oct. 2015, To Mar. 2016

  酒巻和弘
• 細胞死に特異的な細胞収縮に関与するクロライドチャネルの同定とイオン放出機構の解明

  京都大学教育研究振興財団助成金

  From Jul. 2018, To Mar. 2019

  酒巻和弘

Education

Teaching subject(s)

• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Biology and Life Science

  N484, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Course in Studies on Signal Transduction

  1029, Fall, Graduate School of Biostudies, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Molecular and Cell Biology I

  1016, Spring, Graduate School of Biostudies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Molecular and Cell Biology I

  1016, Spring, Graduate School of Biostudies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Introduction to Biology and Life Science

  N484, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Course in Studies on Signal Transduction

  1029, Fall, Graduate School of Biostudies, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• 生命科学概論Ｂ
• From Apr. 2012, To Mar. 2013

  Perspectives on Life Science B

  Fall, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Advanced Course in Studies on Signal Transduction

  Fall, 生命科学研究科
• From Apr. 2013, To Mar. 2014

  Study of Life Science II

  Fall, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Advanced Course in Studies on Signal Transduction

  Fall, 生命科学研究科
• From Apr. 2014, To Mar. 2015

  Study of Life Science II

  Fall, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Advanced Course in Studies on Signal Transduction

  Spring, 生命科学研究科
• From Apr. 2015, To Mar. 2016

  Study of Life Science II

  Fall, 全学共通科目
• From 01 Oct. 2012, To 31 Mar. 2013

  教職総合演習

  Fall
• From Apr. 2016, To Mar. 2017

  Advanced Course in Studies on Signal Transduction

  Spring, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Course in Studies on Signal Transduction

  Fall, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2018, To Mar. 2019

  Advanced Molecular and Cell Biology I

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Course in Studies on Signal Transduction

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Molecular and Cell Biology I

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  ILAS Seminar

  Spring, 全学共通科目
• From Apr. 2019, To Mar. 2020

  Advanced Course in Studies on Signal Transduction

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Molecular and Cell Biology I

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Course in Studies on Signal Transduction

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Molecular and Cell Biology I

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Course in Studies on Signal Transduction

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科

Part-time lecturer

• From 28 Sep. 2016, To 31 Mar. 2017

  神戸大学
• From 21 May 2019, To 31 Mar. 2020

  福井大学

Administration

School management (title, position)

• From 01 Apr. 2008, To 30 Sep. 2016

  京都大学動物実験委員会 委員
• From 01 Apr. 2008, To 31 Mar. 2013

  京都大学教務事務電算管理運営委員会 委員
• From 20 Nov. 2012, To 10 Oct. 2013

  動物実験委員会　外部評価導入ＷＧ 副座長
• From 01 Apr. 2014

  本部構内実験排水系管理委員会　委員
• From 01 Oct. 2016, To 30 Sep. 2018

  京都大学動物実験委員会 委員
• From 01 Apr. 2019, To 31 Mar. 2021

  学生総合支援センター管理運営委員会 委員

Faculty management (title, position)

• From 01 Apr. 2002

  安全・環境保全委員会委員
• From 01 Apr. 2005, To 31 Mar. 2010

  ＲＩ委員会委員
• From 01 Apr. 2006

  動物実験委員会委員
• From 01 Oct. 2012, To 30 Sep. 2013

  奨学金返還免除申請委員会委員
• From 01 Apr. 2018, To 31 Mar. 2019

  国際教育委員会委員
• From 01 Apr. 2019

  SPFマウス実験室管理委員会委員
• From 01 Apr. 2019

  SPFマウス実験室運営委員会委員
• From 01 Mar. 2020, To 30 Sep. 2020

  白眉センター専門委員会委員