Basic Information

Affiliated programs (koza)

• Graduate School of Human and Environmental Studies, 相関環境学専攻 自然環境動態論講座 生物環境動態論ウイルス多様性科学, 准教授

Concurrent Affiliation

• Graduate School of Human and Environmental Studies, 相関環境学専攻 自然環境動態論講座, 協力教員（准教授）
• Institute for Advanced Study, ヒト生物学高等研究拠点, 連携研究者

Professional Memberships

• 日本獣医学会
• 日本エイズ学会
• 日本ウイルス学会

Academic Degree

• Master of Agriculture(University of Tokyo)
• Doctor of Agriculture(University of Tokyo)

Academic Resume (Graduate Schools)

• University of Tokyo, Doctoral course, Graduate School of Agriculture, Veterinary Medicine, 修了
• University of Tokyo, Master's Program, Graduate School of Agriculture, Veterinary Medicine, 修了

Academic Resume (Undergraduate School/Majors)

• University of Tokyo, Faculty of Agriculture, Veterinary Medicine, 卒業

High School

• High School

  岩手県立盛岡第一高等学校

Research History

• From Oct. 2016, To Present

  ウイルス・再生医科学研究所 准教授
• From Apr. 2002, To Sep. 2016

  Kyoto University, Institute for Virus Research
• From Apr. 1998, To Mar. 2002

  Kyoto University, Institute for Virus Research
• From Aug. 1988, To Mar. 1998

  Kyoto University, Institute for Virus Research
• From 1988, To 1998

  Inst. for Virus Research, Kyoto Univ. , Instructor
• To 1998

  1988 Aug.-1998 Apr. Instructor,Inst.for Virus Res.
• From 1998

  Apr.-present Associate Professor,Inst.for Virus Res.
• From Apr. 1988, To Jul. 1988

  日本学術振興会特別研究員
• From 1988

  Apr.-Aug. JSPS research fellow
• Kyoto Univ.

Language of Instruction

• English

ID,URL

• J-Global ID

  200901039459246357

• External link

  https://www2.infront.kyoto-u.ac.jp/primatemodelHP/

Website(s) (URL(s))

• https://www2.infront.kyoto-u.ac.jp/primatemodelHP/

researchmap URL

• https://researchmap.jp/read0013427

Research

Research Topics, Overview of the research

• Research Topics

  Study on infectious diseases using non-human primate model

• Overview of the research

  The origin and evolution of pathogenic retroviruses isolated from the primate in various part of the world including Africa were considered from their molecular phylogenic analysis. In addition, fundamental medical researches for pathogenic elucidation and development of the prevention and the cure by a monkey AIDS model using the monkey/human recombinant AIDS virus.

Research Interests

• 分子進化
• エイズ
• 動物モデル
• レトロウイルス
• molecular evolution
• AIDS
• Animal model
• retrovirus

Research Areas

• Life sciences, Virology
• Life sciences, Veterinary medicine

Papers

• Development of a preclinical monkey model for iPSC-based T cell immunotherapy

  Iriguchi Shoichi; Miyake Yasuyuki; Miura Tomoyuki; Tachikawa Ai; Ueda Tatsuki; Taya Kahoru; Imai Eri; Ishii Hiroshi; Onoe Hirotaka; Matano Tetsuro; Kaneko Shin

  CANCER SCIENCE, Jan. 2018, Peer-reviewed

  
• Development of a novel Macaque-Tropic HIV-1 adapted to cynomolgus macaques

  Hirotaka Ode; Akatsuki Saito; Ayaka Washizaki; Yohei Seki; Takeshi Yoshida; Shigeyoshi Harada; Hiroshi Ishii; Tatsuo Shioda; Yasuhiro Yasutomi; Tetsuro Matano; Tomoyuki Miura; Hirofumi Akari; Yasumasa Iwatani

  Journal of General Virology, 07 Oct. 2022

  
• Re : Genetic Sequence of Segment LTR from Five HTLV-1 Strains Isolated from Three Different Ethnical Groups (caucasians, yellows and negroes) Living in Brazil Preliminary Report

  VERONESI R.; HAYAMI M.; MIURA T.; YAMASHITA M.; NUKUI Y.; CLIQUET M. G.; CHAMONE D.; NEITZERT E.; FOCACCIA R.

  Journal of Epidemiology, Jun. 1995

  
• Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8+ T cells but not CD4+ T cells

  Hiroshi Ishii; Kazutaka Terahara; Takushi Nomura; Midori Okazaki; Hiroyuki Yamamoto; Tsugumine Shu; Hiromi Sakawaki; Tomoyuki Miura; David I Watkins; Tetsuro Matano

  Molecular therapy : the journal of the American Society of Gene Therapy, May 2022, Peer-reviewed

  
• Is SARS-CoV-2 Neutralized More Effectively by IgM and IgA than IgG Having the Same Fab Region?

  Yalcin Pisil; Zafer Yazici; Hisatoshi Shida; Tomoyuki Miura

  Pathogens (Basel, Switzerland), 13 Jun. 2021

  
• Generation of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human disease.

  Yoshihiro Iwamoto; Yohei Seki; Kahoru Taya; Masahiro Tanaka; Shoichi Iriguchi; Yasuyuki Miyake; Emi E Nakayama; Tomoyuki Miura; Tatsuo Shioda; Hirofumi Akari; Akifumi Takaori-Kondo; Shin Kaneko

  Molecular therapy. Methods & clinical development, 11 Jun. 2021

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• Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors.

  Takuya Kobayakawa; Kohei Tsuji; Kiju Konno; Ai Himeno; Ami Masuda; Tingting Yang; Kohei Takahashi; Yusuke Ishida; Nami Ohashi; Takeo Kuwata; Kaho Matsumoto; Kazuhisa Yoshimura; Hiromi Sakawaki; Tomoyuki Miura; Shigeyoshi Harada; Shuzo Matsushita; Hirokazu Tamamura

  Journal of medicinal chemistry, 11 Feb. 2021

  
• A Neutralization Assay Based on Pseudo-Typed Lentivirus with SARS CoV-2 Spike Protein in ACE2-Expressing CRFK Cells.

  Yalçın Pısıl; Hisatoshi Shida; Tomoyuki Miura

  Pathogens (Basel, Switzerland), 02 Feb. 2021

  
• CD8 T Cells Show Protection against Highly Pathogenic Simian Immunodeficiency Virus (SIV) after Vaccination with SIV Gene-Expressing BCG Prime and Vaccinia Virus/Sendai Virus Vector Boosts.

  Seiichi Kato; Hisatoshi Shida; Tomotaka Okamura; Xianfeng Zhang; Tomoyuki Miura; Tetsu Mukai; Makoto Inoue; Tsugumine Shu; Taeko K Naruse; Akinori Kimura; Yasuhiro Yasutomi; Kazuhiro Matsuo

  Journal of virology, 28 Jan. 2021

  
• Quantifying antiviral effects against simian/human immunodeficiency virus induced by host immune response.

  Takafumi Oda; Kwang Su Kim; Yasuhisa Fujita; Yusuke Ito; Tomoyuki Miura; Shingo Iwami

  Journal of theoretical biology, 21 Jan. 2021

  
• A Potent anti-Simian Immunodeficiency Virus Neutralizing Antibody Induction Associated with a Germline Immunoglobulin Gene Polymorphism in Rhesus Macaques.

  Saori Matsuoka; Takeo Kuwata; Hiroshi Ishii; Tsuyoshi Sekizuka; Makoto Kuroda; Masato Sano; Midori Okazaki; Hiroyuki Yamamoto; Mikiko Shimizu; Shuzo Matsushita; Yohei Seki; Akatsuki Saito; Hiromi Sakawaki; Vanessa M Hirsch; Tomoyuki Miura; Hirofumi Akari; Tetsuro Matano

  Journal of virology, 13 Jan. 2021

  
• Detection and genotyping of bovine leukemia virus (BLV) in Vietnamese cattle.

  Dung Thi LE; Nanako Yamashita-Kawanishi; Mari Okamoto; Son Vu Nguyen; Nam Huu Nguyen; Katsuaki Sugiura; Tomoyuki Miura; Takeshi Haga

  The Journal of veterinary medical science, 31 Jul. 2020, Peer-reviewed

  
• Therapeutic vaccine-mediated Gag-specific CD8+ T-cell induction under anti-retroviral therapy augments anti-virus efficacy of CD8+ cells in simian immunodeficiency virus-infected macaques.

  Midori Nakamura-Hoshi; Yusuke Takahara; Saori Matsuoka; Hiroshi Ishii; Sayuri Seki; Takushi Nomura; Hiroyuki Yamamoto; Hiromi Sakawaki; Tomoyuki Miura; Tsuyoshi Tokusumi; Tsugumine Shu; Tetsuro Matano

  Scientific reports, 09 Jul. 2020, Peer-reviewed

  
• Specific Substitutions in Region V2 of gp120 env confer SHIV Neutralisation Resistance.

  Yalcin Pisil; Zafer Yazici; Hisatoshi Shida; Shuzo Matsushita; Tomoyuki Miura

  Pathogens (Basel, Switzerland), 03 Mar. 2020, Peer-reviewed

  
• Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.

  Fumihiro Kato; Yasunori Nio; Kazumi Yagasaki; Rieko Suzuki; Makoto Hijikata; Tomoyuki Miura; Isao Miyazaki; Shigeru Tajima; Chang-Kweng Lim; Masayuki Saijo; Tomohiko Takasaki; Takayuki Hishiki

  Antiviral research, Dec. 2019, Peer-reviewed

  
• 老化・動物モデル HIV-1潜伏感染霊長類モデルにおけるHIV複製リザーバーの定量解析とその意義

  関 洋平; 齊藤 暁; 原田 恵嘉; 村田 めぐみ; 鷲崎 彩夏; 引地 優太; 吉村 和久; 石井 洋; 佐藤 賢文; Saiful Islam M.; 大出 裕高; 岩谷 靖雅; 芳田 剛; 保富 康宏; 俣野 哲朗; 三浦 智行; 明里 宏文

  日本エイズ学会誌, Nov. 2019

  
• in vivo passageで獲得したサル馴化HIV-1のvif遺伝子領域における欠損変異の役割

  松岡 和弘; 中田 佳宏; 鷲崎 彩夏; 芳田 剛; 齊藤 暁; 関 洋平; 大出 裕高; 蜂谷 敦子; 保富 康宏; 原田 恵嘉; 石井 洋; 俣野 哲朗; 三浦 智行; 佐藤 賢文; 明里 宏文; 岩谷 靖雅

  日本エイズ学会誌, Nov. 2019

  
• Revealing uninfected and infected target cell dynamics from peripheral blood data in highly and less pathogenic simian/human immunodeficiency virus infected Rhesus macaque.

  Akane Hara; Shoya Iwanami; Yusuke Ito; Tomoyuki Miura; Shinji Nakaoka; Shingo Iwami

  Journal of theoretical biology, 21 Oct. 2019, Peer-reviewed

  
• Induction of neutralizing antibodies against tier 2 human immunodeficiency virus 1 in rhesus macaques infected with tier 1B simian/human immunodeficiency virus.

  Ai Himeno; Yuki Ishida; Hiromi Mori; Kanako Matsuura; Minako Kikukawa; Hiromi Sakawaki; Tomoyuki Miura

  Archives of virology, May 2019, Peer-reviewed

  
• PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation.

  Kei Miyakawa; Satoko Matsunaga; Masaru Yokoyama; Masako Nomaguchi; Yayoi Kimura; Mayuko Nishi; Hirokazu Kimura; Hironori Sato; Hisashi Hirano; Tomohiko Tamura; Hirofumi Akari; Tomoyuki Miura; Akio Adachi; Tatsuya Sawasaki; Naoki Yamamoto; Akihide Ryo

  Nature communications, 23 Apr. 2019, Peer-reviewed

  
• Experimental infection of Japanese macaques with simian retrovirus 5.

  Rie Koide; Rokusuke Yoshikawa; Munehiro Okamoto; Shoichi Sakaguchi; Juri Suzuki; Tadashi Isa; So Nakagawa; Hiromi Sakawaki; Tomoyuki Miura; Takayuki Miyazawa

  The Journal of general virology, Feb. 2019, Peer-reviewed

  
• Evaluation of Macaca radiata as a non-human primate model of Dengue virus infection.

  Fumihiro Kato; Yuki Ishida; Akihiko Kawakami; Tomohiko Takasaki; Masayuki Saijo; Tomoyuki Miura; Takayuki Hishiki

  Scientific reports, 21 Feb. 2018, Peer-reviewed

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• CXCR4- and CCR5-Tropic HIV-1 Clones Are Both Tractable to Grow in Rhesus Macaques.

  Naoya Doi; Tomoyuki Miura; Hiromi Mori; Hiromi Sakawaki; Takaaki Koma; Akio Adachi; Masako Nomaguchi

  Frontiers in microbiology, 2018, Peer-reviewed

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• In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.

  Sayuri Seki; Takushi Nomura; Masako Nishizawa; Hiroyuki Yamamoto; Hiroshi Ishii; Saori Matsuoka; Teiichiro Shiino; Hironori Sato; Kazuta Mizuta; Hiromi Sakawaki; Tomoyuki Miura; Taeko K Naruse; Akinori Kimura; Tetsuro Matano

  PLoS pathogens, Sep. 2017, Peer-reviewed

  
• In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.

  Sayuri Seki; Takushi Nomura; Masako Nishizawa; Hiroyuki Yamamoto; Hiroshi Ishii; Saori Matsuoka; Teiichiro Shiino; Hironori Sato; Kazuta Mizuta; Hiromi Sakawaki; Tomoyuki Miura; Taeko K Naruse; Akinori Kimura; Tetsuro Matano

  PLoS Pathog., Sep. 2017, Peer-reviewed

  
• A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture.

  Shoya Iwanami; Yusuke Kakizoe; Satoru Morita; Tomoyuki Miura; Shinji Nakaoka; Shingo Iwami

  Theoretical biology & medical modelling, 21 Apr. 2017, Peer-reviewed

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• Duration of SHIV production by infected cells is not exponentially distributed: Implications for estimates of infection parameters and antiviral efficacy.

  Catherine A A Beauchemin; Tomoyuki Miura; Shingo Iwami

  Scientific reports, 16 Feb. 2017, Peer-reviewed

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• Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle.

  Takayuki Hishiki; Fumihiro Kato; Shigeru Tajima; Kazufumi Toume; Masahito Umezaki; Tomohiko Takasaki; Tomoyuki Miura

  Frontiers in microbiology, 2017, Peer-reviewed

  
• MHCを視点とした免疫異常・感染症治療戦略の新展開 HIV-1ワクチン開発とその課題

  志田 壽利; 加藤 誠一; 保富 康宏; 松尾 和浩; 三浦 智行; 五十嵐 樹彦; 張 険峰; 井上 誠; 成瀬 妙子; 木村 彰方

  MHC: Major Histocompatibility Complex, Oct. 2016

  
• Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8(+) T-cell frequencies in a macaque AIDS model.

  Hiroshi Ishii; Saori Matsuoka; Takushi Nomura; Midori Nakamura; Teiichiro Shiino; Yuko Sato; Naoko Iwata-Yoshikawa; Hideki Hasegawa; Kazuta Mizuta; Hiromi Sakawaki; Tomoyuki Miura; Yoshio Koyanagi; Taeko K Naruse; Akinori Kimura; Tetsuro Matano

  Scientific reports, 25 Jul. 2016, Peer-reviewed

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• Novel antiviral activity of bromocriptine against dengue virus replication.

  Fumihiro Kato; Yuki Ishida; Shinya Oishi; Nobutaka Fujii; Satoru Watanabe; Subhash G Vasudevan; Shigeru Tajima; Tomohiko Takasaki; Youichi Suzuki; Koji Ichiyama; Naoki Yamamoto; Kentaro Yoshii; Ikuo Takashima; Takeshi Kobayashi; Tomoyuki Miura; Tatsuhiko Igarashi; Takayuki Hishiki

  Antiviral research, Jul. 2016, Peer-reviewed

  
• Generation of a neutralization-resistant CCR5 tropic simian/human immunodeficiency virus (SHIV-MK38) molecular clone, a derivative of SHIV-89.6.

  Yuki Ishida; Mai Yoneda; Hiroyuki Otsuki; Yuji Watanabe; Fumihiro Kato; Kanako Matsuura; Minako Kikukawa; Shuzo Matsushita; Takayuki Hishiki; Tatsuhiko Igarashi; Tomoyuki Miura

  The Journal of general virology, May 2016, Peer-reviewed

  
• Development of prevention and cure for HIV infection using the nonhuman primate model

  MIURA Tomoyuki

  Current status of infectious diseases of experimental animals and animal models for infectious diseases, Mar. 2016, Invited

  
• A minimally cytotoxic CD4 mimic as an HIV entry inhibitor.

  Takaaki Mizuguchi; Shigeyoshi Harada; Tomoyuki Miura; Nami Ohashi; Tetsuo Narumi; Hiromi Mori; Yu Irahara; Yuko Yamada; Wataru Nomura; Shuzo Matsushita; Kazuhisa Yoshimura; Hirokazu Tamamura

  Bioorganic & medicinal chemistry letters, 15 Jan. 2016, Peer-reviewed

  
• HIV-1 gp120を標的化するmonocyclohexyl type groupを持つ低分子量CD4模倣分子の開発(Development of small CD4 mimic molecules with a mono-cyclohexyl type group targeting HIV-1 gp 120)

  Kotani Misato; Irahara Yu; Ishida Yusuke; Harada Shigeyoshi; Ohashi Nami; Yamada Yuko; Mizuguchi Takaaki; Miura Tomoyuki; Nomura Wataru; Matsushita Shuzo; Yoshimura Kazuhisa; Tamamura Hirokazu

  日本エイズ学会誌, Nov. 2015, Peer-reviewed

  
• Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.

  Kei Sato; Tomoko Kobayashi; Naoko Misawa; Rokusuke Yoshikawa; Junko S Takeuchi; Tomoyuki Miura; Munehiro Okamoto; Jun-ichirou Yasunaga; Masao Matsuoka; Mamoru Ito; Takayuki Miyazawa; Yoshio Koyanagi

  Scientific reports, 14 Sep. 2015, Peer-reviewed

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• A conservation law for virus infection kinetics in vitro

  Yusuke Kakizoe; Satoru Morita; Shinji Nakaoka; Yasuhiro Takeuchi; Kei Sato; Tomoyuki Miura; Catherine A. A. Beauchemin; Shingo Iwami

  JOURNAL OF THEORETICAL BIOLOGY, Jul. 2015, Peer-reviewed

  
• A method to determine the duration of the eclipse phase for in vitro infection with a highly pathogenic SHIV strain

  Yusuke Kakizoe; Shinji Nakaoka; Catherine A. A. Beauchemin; Satoru Morita; Hiromi Mori; Tatsuhiko Igarashi; Kazuyuki Aihara; Tomoyuki Miura; Shingo Iwami

  SCIENTIFIC REPORTS, May 2015, Peer-reviewed

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• Simian retrovirus 4 induces lethal acute thrombocytopenia in Japanese macaques.

  Rokusuke Yoshikawa; Munehiro Okamoto; Shoichi Sakaguchi; So Nakagawa; Tomoyuki Miura; Hirohisa Hirai; Takayuki Miyazawa

  Journal of virology, Apr. 2015, Peer-reviewed

  
• Animal model studies on viral infections

  Akio Adachi; Tomoyuki Miura

  FRONTIERS IN MICROBIOLOGY, Dec. 2014, Peer-reviewed

  
• Generation of a monkey-tropic human immunodeficiency virus type 1 carrying env from a CCR5-tropic subtype C clinical isolate

  Hiroyuki Otsuki; Mai Yoneda; Tatsuhiko Igarashi; Tomoyuki Miura

  VIROLOGY, Jul. 2014, Peer-reviewed

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• Development of a Novel Dengue-1 Virus Replicon System Expressing Secretory Gaussia luciferase for Analysis of Viral Replication and Discovery of Antiviral Drugs

  Fumihiro Kato; Takeshi Kobayashi; Shigeru Tajima; Tomohiko Takasaki; Tomoyuki Miura; Tatsuhiko Igarashi; Takayuki Hishiki

  JAPANESE JOURNAL OF INFECTIOUS DISEASES, May 2014, Peer-reviewed

  
• Development of a novel rhesus macaque model with an infectious R5 simian-human immunodeficiency virus encoding HIV-1 CRF08_BC env

  Li Huang; Shigeru Kusagawa; Haiyan Zeng; Guibo Yang; Binlian Sun; Tomoyuki Miura; Rongge Yang

  JOURNAL OF MEDICAL PRIMATOLOGY, Feb. 2014, Peer-reviewed

  
• Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic

  Hiroyuki Otsuki; Takayuki Hishiki; Tomoyuki Miura; Chie Hashimoto; Tetsuo Narumi; Hirokazu Tamamura; Kazuhisa Yoshimura; Shuzo Matsushita; Tatsuhiko Igarashi

  JOURNAL OF GENERAL VIROLOGY, Dec. 2013, Peer-reviewed

  
• A CD4 mimic as an HIV entry inhibitor: Pharmacokinetics

  Chie Hashimoto; Tetsuo Narumi; Hiroyuki Otsuki; Yuki Hirota; Hiroshi Arai; Kazuhisa Yoshimura; Shigeyoshi Harada; Nami Ohashi; Wataru Nomura; Tomoyuki Miura; Tatsuhiko Igarashi; Shuzo Matsushita; Hirokazu Tamamura

  BIOORGANIC & MEDICINAL CHEMISTRY, Dec. 2013, Peer-reviewed

  
• Generation of rhesus macaque-tropic HIV-1 clones that are resistant to major anti-HIV-1 restriction factors.

  Masako Nomaguchi; Masaru Yokoyama; Ken Kono; Emi E Nakayama; Tatsuo Shioda; Naoya Doi; Sachi Fujiwara; Akatsuki Saito; Hirofumi Akari; Kei Miyakawa; Akihide Ryo; Hirotaka Ode; Yasumasa Iwatani; Tomoyuki Miura; Tatsuhiko Igarashi; Hironori Sato; Akio Adachi

  Journal of virology, Nov. 2013, Peer-reviewed

  
• Natural infection of cynomolgus monkeys with dengue virus occurs in epidemic cycles in the Philippines

  Fumihiro Kato; Yuki Ishida; Takahiro Kawagishi; Takeshi Kobayashi; Takayuki Hishiki; Tomoyuki Miura; Tatsuhiko Igarashi

  JOURNAL OF GENERAL VIROLOGY, Oct. 2013, Peer-reviewed

  
• Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors.

  Masako Nomaguchi; Masaru Yokoyama; Ken Kono; E Emi Nakayama; Tatsuo Shioda; Naoya Doi; Sachi Fujiwara; Akatsuki Saito; Hirofumi Akari; Kei Miyakawa; Akihide Ryo; Hirotaka Ode; Yasumasa Iwatani; Tomoyuki Miura; Tatsuhiko Igarashi; Hironori Sato; Akio Adachi

  Journal of Virology, 21 Aug. 2013, Peer-reviewed

  
• Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic simian-human immunodeficiency virus infection

  Megumi Matsuyama-Murata; Katsuhisa Inaba; Reii Horiuchi; Yoshinori Fukazawa; Kentaro Ibuki; Masanori Hayami; Tomoyuki Miura

  FRONTIERS IN MICROBIOLOGY, Jul. 2013, Peer-reviewed

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• No Viral Evolution in the Lymph Nodes of Simian Immunodeficiency Virus-Infected Rhesus Macaques during Combined Antiretroviral Therapy

  Megu Oue; Saori Sakabe; Mariko Horiike; Mika Yasui; Tomoyuki Miura; Tatsuhiko Igarashi

  JOURNAL OF VIROLOGY, Apr. 2013, Peer-reviewed

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• Generation of a replication-competent chimeric simian-human immunodeficiency virus carrying env from subtype C clinical isolate through intracellular homologous recombination

  Yasuhisa Fujita; Hiroyuki Otsuki; Yuji Watanabe; Mika Yasui; Takeshi Kobayashi; Tomoyuki Miura; Tatsuhiko Igarashi

  Virology, 05 Feb. 2013, Peer-reviewed

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• A Novel Protective MHC-I Haplotype Not Associated with Dominant Gag-Specific CD8(+) T-Cell Responses in SIVmac239 Infection of Burmese Rhesus Macaques

  Naofumi Takahashi; Takushi Nomura; Yusuke Takahara; Hiroyuki Yamamoto; Teiichiro Shiino; Akiko Takeda; Makoto Inoue; Akihiro Iida; Hiroto Hara; Tsugumine Shu; Mamoru Hasegawa; Hiromi Sakawaki; Tomoyuki Miura; Tatsuhiko Igarashi; Yoshio Koyanagi; Taeko K. Naruse; Akinori Kimura; Tetsuro Matano

  PLOS ONE, Jan. 2013, Peer-reviewed

  
• Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

  Mariko Horiike; Shingo Iwami; Makoto Kodama; Akihiko Sato; Yuji Watanabe; Mika Yasui; Yuki Ishida; Takeshi Kobayashi; Tomoyuki Miura; Tatsuhiko Igarashi

  VIROLOGY, Feb. 2012, Peer-reviewed

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• Quantification system for the viral dynamics of a highly pathogenic simian/human immunodeficiency virus based on an in vitro experiment and a mathematical model

  Shingo Iwami; Benjamin P. Holder; Catherine A. A. Beauchemin; Satoru Morita; Tetsuko Tada; Kei Sato; Tatsuhiko Igarashi; Tomoyuki Miura

  RETROVIROLOGY, Feb. 2012, Peer-reviewed

  
• Synthesis and biological evaluation of deoxy-hematoxylin derivatives as a novel class of anti-HIV-1 agents

  Hideki Ishii; Hiroko Koyama; Kyoji Hagiwara; Tomoyuki Miura; Guangai Xue; Yoshie Hashimoto; Genta Kitahara; Yoko Aida; Masaaki Suzuki

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Feb. 2012, Peer-reviewed

  
• Identifying viral parameters from in vitro cell cultures

  Shingo Iwami; Kei Sato; Rob J. De Boer; Kazuyuki Aihara; Tomoyuki Miura; Yoshio Koyanagi

  FRONTIERS IN MICROBIOLOGY, 2012, Peer-reviewed

  
• Major histocompatibility complex class I-restricted cytotoxic T lymphocyte responses during primary simian immunodeficiency virus infection in Burmese rhesus macaques

  Midori Nakamura; Yusuke Takahara; Hiroshi Ishii; Hiromi Sakawaki; Mariko Horiike; Tomoyuki Miura; Tatsuhiko Igarashi; Taeko K. Naruse; Akinori Kimura; Tetsuro Matano; Saori Matsuoka

  MICROBIOLOGY AND IMMUNOLOGY, Nov. 2011, Peer-reviewed

  
• Adaptation of feline immunodeficiency virus subtype B strain TM2 to a feline astrocyte cell line (G355-5 cells)

  Mieko Ishikawa; Kenji Baba; Masayuki Shimojima; Masaya Okada; Takayuki Shojima; Tomoyuki Miura; Takayuki Miyazawa

  VETERINARY MICROBIOLOGY, May 2011, Peer-reviewed

  
• Dominant induction of vaccine antigen-specific cytotoxic T lymphocyte responses after simian immunodeficiency virus challenge

  Yusuke Takahara; Saori Matsuoka; Tetsuya Kuwano; Tetsuo Tsukamoto; Hiroyuki Yamamoto; Hiroshi Ishii; Tadashi Nakasone; Akiko Takeda; Makoto Inoue; Akihiro Iida; Hiroto Nara; Tsugumine Shu; Mamoru Hasegawa; Hiromi Sakawaki; Mariko Horiike; Tomoyuki Miura; Tatsuhiko Igarashi; Taeko K. Naruse; Akinori Kimura; Tetsuro Matano

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2011, Peer-reviewed

  
• Isolation of Potent Neutralizing Monoclonal Antibodies from an SIV-Infected Rhesus Macaque by Phage Display

  Takeo Kuwata; Yuko Katsumata; Kaori Takaki; Tomoyuki Miura; Tatsuhiko Igarashi

  AIDS RESEARCH AND HUMAN RETROVIRUSES, May 2011, Peer-reviewed

  
• Quantifying viral dynamics based on in vitro experiments and mathematical modeling.

  Iwami S; Beauchemin C; Tada T; Igarashi T; Miura T

  IUMS. Japan. September 11-16. 2011., 2011, Peer-reviewed

  
• Peripheral Blood CD4 and CD8 Double-Positive T Cells of Rhesus Macaques Become Vulnerable to Simian Immunodeficiency Virus by In Vitro Stimulation Due to the Induction of CCR5

  Yusuke Matsumoto; Tomoyuki Miura; Hirofumi Akari; Yoshitaka Goto; Takeshi Haga

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Aug. 2010, Peer-reviewed

  
• Evaluation of the immune response and protective effects of rhesus macaques vaccinated with biodegradable nanoparticles carrying gp120 of human immunodeficiency virus

  Ai Himeno; Takami Akagi; Tomofumi Uto; Xin Wang; Masanori Baba; Kentaro Ibuki; Megumi Matsuyama; Mariko Horiike; Tatsuhiko Igarashi; Tomoyuki Miura; Mitsuru Akashi

  VACCINE, Jul. 2010, Peer-reviewed

  
• Differential Diagnosis of Feline Leukemia Virus Subgroups Using Pseudotype Viruses Expressing Green Fluorescent Protein

  Megumi Nakamura; Eiji Sato; Tomoyuki Miura; Kenji Baba; Tetsuya Shimoda; Takayuki Miyazawa

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Jun. 2010, Peer-reviewed

  
• In vivo analysis of a new R5 tropic SHIV generated from the highly pathogenic SHIV-KS661, a derivative of SHIV-89.6

  Kenta Matsuda; Katsuhisa Inaba; Yoshinori Fukazawa; Megumi Matsuyama; Kentaro Ibuki; Mariko Horiike; Naoki Saito; Masanori Hayami; Tatsuhiko Igarashi; Tomoyuki Miura

  VIROLOGY, Mar. 2010, Peer-reviewed

  
• ＨＩＶの起源と進化

  武久盾; 三浦智行

  日本臨床, 01 Mar. 2010

  
• Small intestine CD4(+) cell reduction and enteropathy in simian/human immunodeficiency virus KS661-infected rhesus macaques in the presence of low viral load

  Katsuhisa Inaba; Yoshinori Fukazawa; Kenta Matsuda; Ai Himeno; Megumi Matsuyama; Kentaro Ibuki; Yoshiharu Miura; Yoshio Koyanagi; Atsushi Nakajima; Richard S. Blumberg; Hidemi Takahashi; Masanori Hayami; Tatsuhiko Igarashi; Tomoyuki Miura

  JOURNAL OF GENERAL VIROLOGY, Mar. 2010, Peer-reviewed

  
• [The origin and evolution of HIV].

  Takehisa J; Miura T

  Nihon rinsho. Japanese journal of clinical medicine, Mar. 2010, Peer-reviewed

  
• Estimate of viral productivity and infectivity in vitro. KSIAM,

  S. Iwami; Y. Takeuchi; T. Igarashi; T. Miura

  Chungnam National University, April 24-25 、 2010, 2010, Peer-reviewed

  
• 計算ウイルス学・免疫学の展開- ウイルス感 染力推定法の開発-

  岩見真吾; 多田哲子; 五十嵐樹彦; 三浦智行

  日本応用数理学会、東京、2010 年9 月8 日, 2010, Peer-reviewed

  
• Immune impairment in HIV infection: Existence of risky and immunodeficiency thresholds

  Shingo Iwami; Tomoyuki Miura; Shinji Nakaoka; Yasuhiro Takeuchi

  JOURNAL OF THEORETICAL BIOLOGY, Oct. 2009, Peer-reviewed

  
• Immune impairment thresholds in HIV infection

  Shingo Iwami; Shinji Nakaoka; Yasuhiro Takeuchi; Yoshiharu Miura; Tomoyuki Miura

  IMMUNOLOGY LETTERS, Apr. 2009, Peer-reviewed

  
• Inhibition of human immunodeficiency virus type 1 (HIV-1) nuclear import via Vpr-Importin alpha interactions as a novel HIV-1 therapy

  Tatsunori Suzuki; Norio Yamamoto; Mizuho Nonaka; Yoshie Hashimoto; Go Matsuda; Shin-nosuke Takeshima; Megumi Matsuyama; Tatsuhiko Igarashi; Tomoyuki Miura; Rie Tanaka; Shingo Kato; Yoko Aida

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2009, Peer-reviewed

  
• Trans-species activation of human T cells by rhesus macaque CD1b molecules

  Daisuke Morita; Kumiko Katoh; Toshiyuki Harada; Yoshiaki Nakagawa; Isamu Matsunaga; Tomoyuki Miura; Akio Adachi; Tatsuhiko Igarashi; Masahiko Sugita

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2008, Peer-reviewed

  
• Establishment of a feline astrocyte-derived cell line (G355-5 cells) expressing feline CD134 and a rapid quantitative assay for T-lymphotropic feline immunodeficiency viruses

  Mieko Ishikawa; Masaya Okada; Kenji Baba; Takayuki Shojima; Masayuki Shimojima; Tomoyuki Miura; Takayuki Miyazawa

  JOURNAL OF VIROLOGICAL METHODS, Aug. 2008, Peer-reviewed

  
• Small intestine CD4(+) T cells are profoundly depleted during acute simian-human immunodeficiency virus infection, regardless of viral pathogenicity

  Yoshinori Fukazawa; Ariko Miyake; Kentaro Ibuki; Katsuhisa Inaba; Naoki Saito; Makiko Motohara; Reii Horiuchi; Ai Himeno; Kenta Matsuda; Megumi Matsuyama; Hidemi Takahashi; Masanori Hayami; Tatsuhiko Igarashi; Tomoyuki Miura

  JOURNAL OF VIROLOGY, Jun. 2008, Peer-reviewed

  
• The origin and evolution of AIDS virus

  三浦智行

  Virus report, 31 May 2008

  
• Construction and infection of a new simian/human immunodeficiency chimeric virus (SHIV) containing the integrase gene of the human immunodeficiency virus type 1 genome and analysis of its adaptation to monkey cells

  Hisashi Akiyama; Misa Ishimatsu; Tomoyuki Miura; Masanori Hayami; Eiji Ido

  MICROBES AND INFECTION, Apr. 2008, Peer-reviewed

  
• Live attenuated AIDS vaccine conferred a strong protection against highly pathogenic SHIV challenge.

  Fukazawa Y; Ibuki K; Inaba K; Saito N; Matsuda K; Himeno A; Hirai K; Matsuyama M; Hayami M; Igarashi T; Miura T

  9th Kumomoto AIDS Seminar, Sep.18-19, 2008, Kumamoto, 2008, Peer-reviewed

  
• CD4+ cell reduction and enteropathy in small intestine can be occurred irrespective of viral load in simian/human immunodeficiency virus infection.

  Inaba K; Fukazawa Y; Horiuchi R; Matsuda K; Himeno A; Matsuyama M; Hayami M; Igarashi T; Miura T

  9th Kumomoto AIDS Seminar, Sep.18-19, 2008, Kumamoto, 2008, Peer-reviewed

  
• Genes, proteins and function of monkey group 1 CD1

  D. MORITA; K. KATOH; I. MATSUNAGA; T. MIURA; T. IGARASHI; M. SUGITA

  (1) Laboratory of Primate Model, IVR Biochem. Biophys. Res. Commun. 377:889, 2008, 2008, Peer-reviewed

  
• A genetically engineered live-attenuated simian-human immunodeficiency virus that co-expresses the RANTES gene improves the magnitude of cellular immunity in rhesus macaques

  Yuya Shimizu; Katsuhisa Inaba; Kentaro Kaneyasu; Kentaro Ibuki; Ai Himeno; Masashi Okoba; Yoshitaka Goto; Masanori Hayami; Tomoyuki Miura; Takeshi Haga

  Virology, 25 Apr. 2007

  
• Construction of a novel SHIV having an HIV-1-derived protease gene and its infection to rhesus macaques: a useful tool for in vivo efficacy tests of protease inhibitors

  Misa Ishimatsu; Hajime Suzuki; Hisashi Akiyama; Tomoyuki Miura; Masanori Hayami; Eiji Ido

  MICROBES AND INFECTION, Apr. 2007, Peer-reviewed

  
• Contribution of monocytes to viral replication in macaques during acute infection with simian immunodeficiency virus

  Takeo Kuwata; Makoto Kodama; Akihiko Sato; Hajime Suzuki; Yasuyuki Miyazaki; Tomoyuki Miura; Masanori Hayami

  AIDS Research and Human Retroviruses, Mar. 2007, Peer-reviewed

  
• Virological and immunological analysis of systemic lymphoid tissues in SHIV-infected monkeys.

  Ibuki K; Inaba K; Fukazawa Y; Matsuyama M; Hayami M; Miura T

  US-Japan Cooperative Medical Science Program: 20th Joint Meeting of the AIDS Panels, Monterey, CA, U.S. A., Sep. 13-14, 2007, 2007, Peer-reviewed

  
• Whole genome sequence data of an infectious molecular clone of the SIVagm TYO-1 strain

  Tomoyuki Miura; Megumi Matsuyama; Fumiko Ogatsu; Masanori Hayami

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Nov. 2006, Peer-reviewed

  
• Investigation of acute pathogenesis of simian and human immunodeficiency chimeric virus by comparison of its molecular

  Kozyrev Yury L; Sakai Koji; Takahashi Eiji; Shinohara Katsuaki; Takemura Taichiro; Inaba Katsuhisa; Suzuki Hajime; Ibuki Kentaro; Hayami Masanori; Miura Tomoyuki

  JOURNAL OF MEDICAL PRIMATOLOGY, Aug. 2006, Peer-reviewed

  
• In vitro and in vivo stability of plasmids in attenuated salmonella enterica serovar typhimurium used as a carrier of DNA vaccine is associated with its replication origin

  Takeshi Haga; Shino Kumabe; Ai Ikejiri; Yuya Shimizu; Huang Li; Yoshitaka Goto; Hidenori Matsui; Hironori Miyata; Tomoyuki Miura

  EXPERIMENTAL ANIMALS, Jul. 2006, Peer-reviewed

  
• In vitro and in vivo stability of plasmids in attenuated salmonella enterica serovar typhimurium used as a carrier of DNA vaccine is associated with its replication origin

  Takeshi Haga; Shino Kumabe; Ai Ikejiri; Yuya Shimizu; Huang Li; Yoshitaka Goto; Hidenori Matsui; Hironori Miyata; Tomoyuki Miura

  EXPERIMENTAL ANIMALS, Jul. 2006, Peer-reviewed

  
• Impaired T-cell differentiation in the thymus at the early stages of acute pathogenic chimeric simian-human immunodeficiency virus (SHIV) infection in contrast to less pathogenic SHIV infection

  Makiko Motohara; Kentaro Ibuki; Ariko Miyake; Yoshinori Fukazawa; Katsuhisa Inaba; Hajime Suzuki; Kyoko Masuda; Nagahiro Minato; Hiroshi Kawamoto; Tadashi Nakasone; Mitsuo Honda; Masanori Hayami; Tomoyuki Miura

  MICROBES AND INFECTION, May 2006, Peer-reviewed

  
• Rapid dissemination of a pathogenic simian/human immunodeficiency virus to systematic organs and active replication in lymphoid tissues following intrarectal infection

  Ariko Miyake; Kentaro Ibuki; Yoshimi Enose; Hajime Suzuki; Reii Horiuchi; Makiko Motohara; Naoki Saito; Tadashi Nakasone; Mitsuo Honda; Toshiki Watanabe; Tomoyuki Miura; Masanori Hayami; Masanori Hayami

  Journal of General Virology, May 2006, Peer-reviewed

  
• DNA vaccination of macaques by a full-genome SHIV plasmid that has an IL-2 gene and produces non-infectious virus particles

  R Horiuchi; W Akahata; T Kuwata; Y Enose; E Ido; H Suzuki; A Miyake; N Saito; K Buki; T Goto; T Miura; M Hayami

  VACCINE, Apr. 2006, Peer-reviewed

  
• Generation of a novel SHIV that possesses HIV-1-derived integrase gene in addition to reverse transcriptase gene and its infection to macaque monkeys.

  Ido E; Ishimatsu M; Akiyama H; Ibuki K; Miura T; Hayami M

  US-Japan Cooperative Medical Science Program, 19th Joint Meeting of the AIDS Panels, Kagoshima, December 6-7, 2006, 2006, Peer-reviewed

  
• Full genome sequence analysis in systemic tissues of acute pathogenic SHIV-infected monkeys.

  Matsuyama M; Inaba K; Fukazawa Y; Horiuch R; Ibuki K; Hayami M; Miura T

  US-Japan Cooperative Medical Science Program 19th Joint Meeting of the AIDS Panels, Dec. 6-7, Kagoshima, 2006, Peer-reviewed

  
• In vitro and In vivo properties of chimeric simian and human immunodeficiency viruses having human RANTES genes.

  Shimizu Y; Okoba M; Ibuki K; Kaneyasu K; Goto Y; Miura T; Hayami M; Haga T

  Keystone Symposia HIV Vaccines, March 27-April 2, 2006, keystone,Colorado, USA, 2006, Peer-reviewed

  
• Construction and in vitro characterization of a chimeric simian and human immunodeficiency virus with the RANTES gene

  Yuya Shimizu; Masashi Okoba; Nanase Yamazaki; Yoshitaka Goto; Tomoyuki Miura; Masanori Hayami; Hiroo Hoshino; Takeshi Haga

  Microbes and Infection, Jan. 2006, Peer-reviewed

  
• Induction of immune response in macaque monkeys infected with simian-human immunodeficiency virus having the TNF-α gene at an early stage of infection

  Yuya Shimizu; Yasuyuki Miyazaki; Kentaro Ibuki; Hajime Suzuki; Kentaro Kaneyasu; Yoshitaka Goto; Masanori Hayami; Tomoyuki Miura; Takeshi Haga

  Virology, 20 Dec. 2005, Peer-reviewed

  
• Analysis of evolutionary conservation in CD1d molecules among primates

  N Saito; M Takahashi; W Akahata; E Ido; C Hidaka; K Ibuki; T Miura; M Hayami; H Takahashi

  TISSUE ANTIGENS, Dec. 2005, Peer-reviewed

  
• Early virological events in various tissues of newborn monkeys after intrarectal infection with pathogenic simian human immunodeficiency virus

  Ariko Miyake; Kentaro Ibuki; Hajime Suzuki; Reii Horiuchi; Naoki Saito; Makiko Motohara; Masanori Hayami; Tomoyuki Miura

  Journal of Medical Primatology, Oct. 2005, Peer-reviewed

  
• Comparison of susceptibility to SIVmac239 infection between CD4(+) and CD4(+)8(+) T cells

  M Takahashi; E Ido; H Uesaka; T Fukushima; K Ibuki; T Miura; M Hayami; H Takahashi

  ARCHIVES OF VIROLOGY, Aug. 2005, Peer-reviewed

  
• Phylogenetic heterogeneity of new HTLV type 1 isolates from southern India in subgroup A

  S Ohkura; M Yamashita; T Ishida; PG Babu; Y Koyanagi; N Yamamoto; T Miura; M Hayami

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Apr. 2005, Peer-reviewed

  
• Intrathymic effect of acute pathogenic SHIV infection on T-lineage cells in newborn macaques

  H Suzuki; M Motohara; A Miyake; K Ibuki; Y Fukazawa; K Inaba; K Masuda; N Minato; H Kawamoto; M Hayami; T Miura

  MICROBIOLOGY AND IMMUNOLOGY, 2005, Peer-reviewed

  
• Protective efficacy of nonpathogenic nef-deleted SHIV vaccination combined with recombinant IFN-γ administration against a pathogenic SHIV challenge in rhesus monkeys

  Kentaro Kaneyasu; Masakazu Kita; Sadayuki Ohkura; Toshiro Yamamoto; Kentaro Ibuki; Yoshimi Enose; Akihiko Sato; Makoto Kodama; Tomoyuki Miura; Masanori Hayami

  Microbiology and Immunology, 2005, Peer-reviewed

  
• Protective effects of nef-deleted SHIV or that having IFN-γ against disease induced with a pathogenic virus early after vaccination

  Y. Enose; M. Kita; T. Yamamoto; H. Suzuki; A. Miyake; R. Horiuchi; K. Ibuki; K. Kaneyasu; T. Kuwata; E. Takahashi; K. Sakai; K. Shinohara; T. Miura; M. Hayami

  Archives of Virology, Sep. 2004, Peer-reviewed

  
• Augmentation of antigen-specific cytokine responses in the early phase of vaccination with a live-attenuated simian/human immunodeficiency chimeric virus expressing IFN-γ

  T. Iida; T. Kuwata; M. Ui; H. Suzuki; T. Miura; K. Ibuki; H. Takahashi; T. Yamamoto; J. Imanishi; M. Hayami; M. Kita

  Archives of Virology, Apr. 2004, Peer-reviewed

  
• Linkage of amino acid variation and evolution of human immunodeficiency virus type 1 gp120 envelope glycoprotein (subtype B) with usage of the second receptor

  Y Yamaguchi-Kabata; M Yamashita; S Ohkura; M Hayami; T Miura

  JOURNAL OF MOLECULAR EVOLUTION, Mar. 2004, Peer-reviewed

  
• Construction and in vivo infection of a new simian/human immunodeficiency virus chimera containing the reverse transcriptase gene and the 3′ half of the genomic region of human immunodeficiency virus type 1

  Hisashi Akiyama; Eiji Ido; Wataru Akahata; Takeo Kuwata; Tomoyuki Miura; Masanori Hayami

  Journal of General Virology, 01 Jul. 2003, Peer-reviewed

  
• ＩＦＮ‐γ遺伝子組込み弱毒ＳＨＩＶのワクチン効果

  喜多正和; 榎瀬良美; 宇賀神秀樹; 横山京子; 鈴木元; 桑田岳夫; 三浦智行; 阪井弘治; 高橋栄治

  日本エイズ学会誌, 20 May 2003

  
• Characterization of vpr vector constructed from chimeric simian and human immunodeficiency virus

  T Haga; M Okoba; N Yamazaki; S Kumabe; Y Shimizu; Y Goto; T Kuwata; IL Kozyrev; M Hayami; T Miura

  JOURNAL OF VETERINARY MEDICAL SCIENCE, May 2003, Peer-reviewed

  
• HIV type 1 infection in Pygmy hunter gatherers is from contact with Bantu rather than from nonhuman primates

  Nicaise Ndembi; Habakkuk Yumo; Jun Takehisa; Taichiro Takemura; Eiji Kobayashi; Charlotte Ngansop; Elijah Songok; Tomoyuki Miura; Eiji Ido; Masanori Hayami; Lazare Kaptue; Hiroshi Ichimura

  AIDS Research and Human Retroviruses, 01 May 2003

  
• Comparative histopathological studies in the early stages of acute pathogenic and nonpathogenic SHIV-infected lymphoid organs

  T Shimada; H Suzuki; M Motohara; T Kuwata; K Ibuki; M Ui; T Iida; M Fukumoto; T Miura; H Masanori

  VIROLOGY, Feb. 2003, Peer-reviewed

  
• Comparative histopathological studies in the early stages of acute pathogenic and nonpathogenic SHIV-infected lymphoid organs

  T Shimada; H Suzuki; M Motohara; T Kuwata; K Ibuki; M Ui; T Iida; M Fukumoto; T Miura; H Masanori

  VIROLOGY, Feb. 2003, Peer-reviewed

  
• 「成人T網胞白血病ウイルスの系統分析と人類の移動」

  三浦智行

  cience of Humanity, 42:50-59 頁, 2003, Peer-reviewed

  
• Phylogenetic analysis of HTLV-1 and STLV --The past movement of HTLV-1 Carriers and the origin of PTLV—

  Taichiro TakemuraOhkura S; Miura T; Yamashita M; Ibuki K; Takemura T; Hayami M

  Gann Monograph on Cancer Research, 2003, Peer-reviewed

  
• High prevalence of simian T-lymphotropic virus type L in wild Ethiopian baboons

  T Takemura; M Yamashita; MK Shimada; S Ohkura; T Shotake; M Ikeda; T Miura; M Hayami

  JOURNAL OF VIROLOGY, Feb. 2002, Peer-reviewed

  
• Characterization of simian and human immunodeficiency chimeric viruses re-isolated from vaccinated macaque monkeys after challenge infection

  T. B. Kwofie; T. Miura; K. Ibuki; Y. Enose; H. Suzuki; M. Ui; T. Kuwata; M. Hayami

  Archives of Virology, 2002, Peer-reviewed

  
• Infection of macaques with chimeric simian and human immunodeficiency viruses containing Env from subtype F

  T. Kuwata; T. Takemura; J. Takehisa; T. Miura; M. Hayami

  Archives of Virology, 2002, Peer-reviewed

  
• Co-expression of interleukin-5 influences replication of simian/human immunodeficiency viruses in vivo

  Iouri L. Kozyrev; Tomoyuki Miura; Taichiro Takemura; Takeo Kuwata; Masahiro Ui; Kentaro Ibuki; Tohko Iida; Masanori Hayami

  Journal of General Virology, 2002, Peer-reviewed

  
• Protection by intranasal immunization of a nef-deleted, nonpathogenic SHIV against intravaginal challenge with a heterologous pathogenic SHIV

  Yoshimi Enose; Masahiro Ui; Ariko Miyake; Hajime Suzuki; Hiromi Uesaka; Takeo Kuwata; Jun Kunisawa; Hiroshi Kiyono; Hidemi Takahashi; Tomoyuki Miura; Masanori Hayami

  Virology, 2002

  
• Construction and in vitro properties of chimeric simian and human immunodeficiency virus with the human TNF-alpha gene

  Takeshi Haga; Yuya Shimizu; Masashi Okoba; Shino Kumabe; Yoshitaka Goto; Toshiharu Shinjo; Hiroshi Ichimura; Takeo Kuwata; Masanori Hayami; Tomoyuki Miura

  Microbiology and Immunology, 2002

  
• Apoptosis induced by in vitro infection with simian-human immunodeficiency chimeric virus in macaque and human peripheral blood mononuclear cells

  T Iida; M Kita; T Kuwata; T Miura; K Ibuki; M Ui; M Hayami; J Imanishi

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Oct. 2001, Peer-reviewed

  
• Natural infection of wild-born mandrills (Mandrillus sphinx) with two different types of simian immunodeficiency virus

  Jun Takehisa; Yosuke Harada; Nicaise Ndembi; Innocent Mboudjeka; Yuko Taniguchi; Charlotte Ngansop; Seraphin Kuate; Leopold Zekeng; Kentaro Ibuki; Toshihide Shimada; Blaise Bikandou; Yumi Yamaguchi-Kabata; Tomoyuki Miura; Mikio Ikeda; Hiroshi Ichimura; Lazare Kaptue; Masanori Hayami

  AIDS Research and Human Retroviruses, 10 Aug. 2001

  
• A mathematical model for experimental gene evolution

  T Miura; P Sonigo

  JOURNAL OF THEORETICAL BIOLOGY, Apr. 2001, Peer-reviewed

  
• Characterization of less pathogenic infectious molecular clones derived from acute-pathogenic SHIV-89.6P stock virus

  IL Kozyrev; K Ibuki; T Shimada; T Kuwata; T Takemura; M Hayami; T Miura

  VIROLOGY, Mar. 2001, Peer-reviewed

  
• Apoptosis induced by in vitro infection with simian/human

  Iida,T; Kita, M; Kuwata, T; Miura, T; Ibuki, K; Ui,M; Hayami; M .Imanishi,J

  immunodeficiency chimeric virus in macaque and human PBMC. AIDS Res. Hum. Retroviruses,17(14):1387-1393. 2001, 2001, Peer-reviewed

  
• Phylogenetic characterization of a new HTLV type 1 from the Ainu in Japan

  Masahiro Yamashita; Takafumi Ishida; Sadayuki Ohkura; Tomoyuki Miura; Masanori Hayami

  AIDS Research and Human Retroviruses, 2001, Peer-reviewed

  
• Cytokine kinetics in the plasma of monkeys infected with pathogenic and nonpathogenic simian and human immunodeficiency chimeric viruses at an early stage of infection

  Theophilus B. Kwofie; Takeshi Haga; Tohko Iida; Masanori Hayami; Tomoyuki Miura

  Microbiology and Immunology, 01 Jan. 2001

  
• Construction of SIV/HIV-1 chimeric viruses having the IL-5 gene and determination of their ability to replicate and produce IL-5

  I. L. Kozyrev; T. Miura; T. Haga; T. Kuwata; M. Hayami

  Archives of Virology, 2001

  
• A single amino acid change at Leu-188 in the reverse transcriptase of HIV-2 and SIV renders them sensitive to non-nucleoside reverse transcriptase inhibitors

  Y. Isaka; S. Miki; S. Kawauchi; A. Suyama; H. Sugimoto; A. Adachi; T. Miura; M. Hayami; O. Yoshie; T. Fujiwara; A. Sato

  Archives of Virology, 2001, Peer-reviewed

  
• Construction of an SIV/HIV type 1 chimeric virus with the human interleukin 6 gene and its production of interleukin 6 in monkey and human cells

  Takeshi Haga; Takeo Kuwata; Ioury Kozyrev; Theophilus B. Kwofie; Masanori Hayami; Tomoyuki Miura

  AIDS Research and Human Retroviruses, 10 Apr. 2000

  
• Dox-dependent SIVmac with tetracycline-inducible promoter in the U3 promoter region

  Y Xiao; T Kuwata; T Miura; M Hayami; H Shida

  VIROLOGY, Apr. 2000, Peer-reviewed

  
• Construction of chimeric simian and human immunodeficiency viruses that produce interleukin 12

  Takeo Kuwata; Tomoyuki Miura; Takeshi Haga; Ioury Kozyrev; Masanori Hayami

  AIDS Research and Human Retroviruses, 20 Mar. 2000

  
• Plasma Levels of the Chemokine RANTES in Macaque Monkeys Infected with Pathogenic and Non-Pathogenic SIV/HIV-1 Chimeric Viruses at an Early Stage of Infection

  Theophilus B. Kwofie; Takeshi Haga; Tohko Iida; Masanori Hayami; Tomoyuki Miura

  Journal of Veterinary Medical Science, 2000

  
• Protection of macaques against a SHIV with a homologous HIV-1 Env and a pathogenic SHIV-89.6P with a heterologous Env by vaccination with multiple gene-deleted SHIVs

  Masahiro Ui; Takeo Kuwata; Tatsuhiko Igarashi; Kentaro Ibuki; Yasuyuki Miyazaki; Iouly L. Kozyrev; Yoshimi Enose; Toshihide Shimada; Hiromi Uesaka; Hiroshi Yamamoto; Tomoyuki Miura; Masanori Hayami

  Virology, 20 Dec. 1999, Peer-reviewed

  
• Protective effects against simian immunodeficiency virus agm (SIVagm) infection in cynomolgus monkeys immunized with a recombinant vaccinia virus expressing the SIVagm envelope gene

  Kentaro Ibuki; Eiji Ido; Shin-Ichi Funahashi; Tomoyuki Miura; Masanori Hayami; Hisatoshi Shida

  Vaccine, 14 Oct. 1999, Peer-reviewed

  
• Molecular epidemiology of human T-cell leukemia virus type I (HTLV-I) in Brazil: The predominant HTLV-Is in South America differ from HTLV-Is of Japan and Africa, as well as those of Japanese immigrants and their relatives in Brazil

  M. Yamashita; R. Veronesi; M. Menna-Barreto; Jr Harrington W.J.; C. Sampio; C. Brites; R. Badaro; A. de Souza Andrade-Filho; S. Ohkura; T. Igarashi; J. Takehisa; T. Miura; D. Chamone; O. Bianchini; C. Jardim; S. Sonoda; M. Hayami

  Virology, 15 Aug. 1999, Peer-reviewed

  
• Human immunodeficiency virus type 1 intergroup (M/O) recombination in Cameroon

  J Takehisa; L Zekeng; E Ido; Y Yamaguchi-Kabata; Mboudjeka, I; Y Harada; T Miura; L Kaptue; M Hayami

  JOURNAL OF VIROLOGY, Aug. 1999, Peer-reviewed

  
• HIV type 1 genetic variability in the northern part of Cameroon

  Mboudjeka, I; L Zekeng; J Takehisa; T Miura; E Ido; M Yamashita; L Kaptue; M Hayami

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Jul. 1999, Peer-reviewed

  
• A new genotype of TT virus (TTV) infection among Colombian native Indians

  Yasuhito Tanaka; Masashi Mizokami; Etsuro Orito; Tatsunori Nakano; Takanobu Kato; Xin Ding; Tomoyoshi Ohno; Ryuzo Ueda; Shunro Sonoda; Kazuo Tajima; Tomoyuki Miura; Masanori Hayami

  Journal of Medical Virology, 1999, Peer-reviewed

  
• Natural infection of chimpanzees with new lentiviruses related to HIV-1/SIVcpz

  Jun Takehisa; Biaise Bikandou; Eiji Ido; Innocent Mboudjeka; Reine M'Vouenze; Marie-Yvonne Nzoukoudi; Yosuke Harada; Yumi Yamaguchi-Kabata; Tomoyuki Miura; Michel M'Pandi; Henri Jopseph Parra; Pierre M'Pelé; Masanori Hayami

  Journal of Medical Primatology, 1999, Peer-reviewed

  
• Genetic diversity of HIV-1 group M from Cameroon and Republic of Congo

  I. Mboudjeka; B. Bikandou; L. Zekeng; J. Takehisa; Y. Harada; Y. Yamaguchi-Kabata; Y. Taniguchi; E. Ido; L. Kaptue; P. M'pelle; H. J. Parra; M. Ikeda; M. Hayami; T. Miura

  Archives of Virology, 1999, Peer-reviewed

  
• Various types of HIV mixed infections in Cameroon

  J Takehisa; L Zekeng; E Ido; Mboudjeka, I; H Moriyama; T Miura; M Yamashita; LG Gurtler; M Hayami; L Kaptue

  VIROLOGY, May 1998, Peer-reviewed

  
• GB virus C/hepatitis G virus infection among Colombian native Indians

  Yasuhito Tanaka; Masashi Mizokami; Etsuro Orito; Ken-Ichi Ohba; Tatsunori Nakano; Takanobu Kato; Yutaka Kondo; Xin Ding; Ryuzo Ueda; Shunro Sonoda; Kazuo Tajima; Tomoyuki Miura; Masanori Hayami

  American Journal of Tropical Medicine and Hygiene, 1998

  
• Phylogenetic analysis of human immunodeficiency virus 1 in Ghana

  J Takehisa; M OseiKwasi; NK Ayisi; O Hishida; T Miura; T Igarashi; J Brandful; W Ampofo; VBA Netty; M Mensah; M Yamashita; E Ido; M Hayami

  ACTA VIROLOGICA, Feb. 1997, Peer-reviewed

  
• Molecular phylogeny of human T-cell leukemia virus type I and II of Amerindians in Colombia and Chile

  T Miura; M Yamashita; Zaninovic, V; L Cartier; J Takehisa; T Igarashi; E Ido; T Fujiyoshi; S Sonoda; K Tajima; M Hayami

  JOURNAL OF MOLECULAR EVOLUTION, 1997, Peer-reviewed

  
• Prevalence and phylogenetic analysis of HTLV-I isolates in Cameroon, including those of the Baka Pygmy

  Innocent Mboudjeka; Leopold Zekeng; Masahiro Yamashita; Jun Takehisa; Eiji Ido; Tomoyuki Miura; Sadayuki Ohkura; Mikio Ikeda; Lazare Kaptue; Masanori Hayami

  Japanese Journal of Cancer Research, 1997, Peer-reviewed

  
• Isolation of STLV-I from orangutan, a great ape species in southeast Asia, and its relation to other HTLV-Is/STLV-Is

  Kentaro Ibuki; Eiji Ido; Surachmi Setiyaningsih; Masahiro Yamashita; Lelana R. P. Agus; Jun Takehisa; Tomoyuki Miura; Sajuthi Dondin; Masanori Hayami

  Japanese Journal of Cancer Research, 1997, Peer-reviewed

  
• Phylogenetic relationships of HTLV-I/STLV-I in the world

  M. Yamashita; T. Miura; K. Ibuki; J. Takehisa; J. Chen; E. Ido; M. Hayami

  Leukemia, 1997, Peer-reviewed

  
• Long-term persistence of protective immunity in cynomolgus monkeys immunized with a recombinant vaccinia virus expressing the human T cell leukaemia virus type I envelope gene

  Kentaro Ibuki; Shin-Ichi Funahashi; Hiroshi Yamamoto; Masami Nakamura; Tatsuhiko Igarashi; Tomoyuki Miura; Eiji Ido; Masanori Hayami; Hisatoshi Shida

  Journal of General Virology, 1997, Peer-reviewed

  
• Phylogenetic analysis of HIV type 2 in Ghana and intrasubtype recombination in HIV type 2

  J. Takehisa; M. Osei-Kwasi; N.K. Ayisi; O. Hishida; T. Miura; T. Igarashi; J. Brandful; W. Ampofo; V.B.A. Netty; M. Mensah; M. Yamashita; E. Ido; M. Hayami

  AIDS Research and Human Retroviruses, 1997, Peer-reviewed

  
• Chimeric viruses between SIVmac and various HIV-1 isolates have biological properties that are similar to those of the parental HIV-1

  T Kuwata; T Shioda; T Igarashi; E Ido; K Ibuki; Y Enose; C StahlHennig; G Hunsmann; T Miura; M Hayami

  AIDS, Oct. 1996, Peer-reviewed

  
• Phylogenetic characterization of Simian T Lymphotropic Virus type I (STLV-I) from the Ethiopian sacred baboon (Papio hamadryas)

  Alexander Voevodin; Tomoyuki Miura; Elena Samilchuk; Hermann Schätzl

  AIDS Research and Human Retroviruses, 10 Feb. 1996, Peer-reviewed

  
• Genetic complementation between replication-defective mutants of HIV-1 and SIVagm

  T Miura; R Shibata; A Adachi; T Kuwata; J Chen; M Jin; E Ido; M Hayami

  ARCHIVES OF VIROLOGY, 1996, Peer-reviewed

  
• Molecular epidemiology of HTLV-I in the world

  M Yamashita; E Ido; T Miura; M Hayami

  JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1996, Peer-reviewed

  
• Replication and cytopathogenicity of human immunodeficiency virus type 1 (HIV-1)/simian immunodeficiency virus agm3 chimeric viruses in human and monkey cells: The 5' half of the HIV-1 genome is responsible for virus cytopathogenicity

  Minghao Jin; Eiji Ido; Takeo Kuwata; Tatsuhiko Igarashi; Klaus Cichutek; Reinhard Kurth; Tomoyuki Miura; Yoshimi Enose; Jiangli Chen; Masanori Hayami

  Journal of General Virology, 1996, Peer-reviewed

  
• The phylogenetic relationship of HTLV type I from non-Mashhadi Iranians to that from Mashhadi Jews

  M Yamashita; B Kitze; T Miura; T Weber; T Fujiyoshi; J Takehisa; JL Chen; S Sonoda; M Hayami

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Dec. 1995, Peer-reviewed

  
• HTLV type I isolated from a Pygmy in Cameroon is related to but distinct from the known Central African type

  JL Chen; L Zekeng; M Yamashita; J Takehisa; T Miura; E Ido; Mboudjeka, I; JM Tsague; M Hayami; L Kaptue

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Dec. 1995, Peer-reviewed

  
• Prevalence and phylogenetic characterization of HTLV-I isolates from Far Eastern Russia

  Yamashita, M; Senyuta, NB; Pavlish, OA; Miura, T; Syrtsev, AV; Gurova, EP; Stepina, VN; Ibuki, K; Susova, OY; Shcherbak, LN; Schatzl, H; Shih, J; Yakovleva, LS; Weber, J; Malet, C; Gessain, A; deThe, G; Hayami, M; Gurtsevich, VE

  MOLECULAR BIOLOGY, Sep. 1995, Peer-reviewed

  
• HTL V-I from Iranian Mashhadi Jews in Israel is phylogenetically related to that of Japan, India, and South America rather than to that of Africa and Melanesia

  Masahiro Yamashita; Anat Achiron; Tomoyuki Miura; Jun Takehisa; Eiji Ido; Tatsuhiko Igarashi; Kentaro Ibuki; Mitsuhiro Osame; Shunro Sonoda; Eldad Melamed; Masanori Hayami; Batya Shohat

  Virus Genes, Feb. 1995, Peer-reviewed

  
• Letters to the Editor Letters to the editor will be published, if suitable, as space permits: They may be subject to editing or abridgement

  R. Veronesi; M. Hayami; T. Miura; M. Yamashita; Y. Nukui; M. G. Cliquet; D. Chamone; E. Neitzert; R. Focaccia

  Journal of Epidemiology, 1995, Peer-reviewed

  
• Ethnic segregation of HTLV‐I and HTLV‐II carriers among South American native Indians

  Toshinobu Fujiyoshi; Shinji Yashiki; Chihaya Fujiyama; Masahiro Kuwayama; Hiroki Miyashita; Hiroshi Ohnishi; Michelle Blank; Vladimir Zaninovic; Abraham Blank; Luis Cartier; John J. Byrnes; William J. Harrington; Tomoyuki Miura; Masanori Hayami; Kazuo Tajima; Shunro Sonoda

  International Journal of Cancer, 1995, Peer-reviewed

  
• Molecular Characterization of Human T-Lymphotropic Virus, Type 1 (HTLV-1) Found in Kuwait: Close Similarity with HTLV-1 Isolates Originating from Mashhad, Iran

  Alexander Voevodin; Siham Mufti; Sameer Farah; Ryad Khan; Tomoyuki Miura

  AIDS Research and Human Retroviruses, 1995, Peer-reviewed

  
• SEROLOGICAL SURVEY OF HIV-1, HIV-2 AND HUMAN T-CELL LEUKEMIA-VIRUS TYPE-1 FOR SUSPECTED AIDS CASES IN GHANA

  O HISHIDA; NK AYISI; M AIDOO; J BRANDFUL; W AMPOFO; M OSEIKWASI; E IDO; T IGARASHI; J TAKEHISA; T MIURA; A MIYAZAKI; M HAYAMI

  AIDS, Sep. 1994, Peer-reviewed

  
• Subtype Analysis of HTLV‐1 in Patients with HTLV‐1 Uveitis

  Ayako Ono; Tomoyuki Miura; Shinji Araki; Kazunari Yamaguchi; Kiyoshi Takatsuki; Sigeo Mori; Masanori Hayami; Manabu Mochizuki; Toshiki Watanabe

  Japanese Journal of Cancer Research, 1994, Peer-reviewed

  
• Geographic Independence of HTLV-I and HTLV-II Foci in the Andes Highland, the Atlantic Coast, and the Orinoco of Colombia

  Vladimir Zaninovic; Fernando Sanzon; Fidel Lopez; Guillermo Velandia; Abraham Blank; Michelle Blank; Chihaya Fujiyama; Shinji Yashiki; Daiten Matsumoto; Yoshihiko Katahira; Hiroki Miyashita; Toshinobu Fujiyoshi; Lily Chan; Takashi Sawada; Tomoyuki Miura; Masanori Hayami; Kazuo Tajima; Shunro Sonoda

  AIDS Research and Human Retroviruses, 1994, Peer-reviewed

  
• Persistent Infection with SIVmac Chimeric Virus Having tat, rev, vpu, env and nef of HIV Type 1 in Macaque Monkeys

  Tatsuhiko Igarashi; Riri Shibata; Futoshi Hasebe; Yasushi Ami; Katsuaki Shinohara; Toshihiko Komatsu; Christiane Stahl-Hennig; Harald Petry; Gerhard Hunsmann; Takeo Kuwata; Minghao Jin; Akio Adachi; Takashi Kurimura; Mineyuki Okada; Tomoyuki Miura; Masanori Hayami

  AIDS Research and Human Retroviruses, 1994, Peer-reviewed

  
• Isolation and characterization of simian immunodeficiency virus from African white-crowned mangabey monkeys (Cercocebus torquatus lunulatus)

  K. Tomonaga; J. Katahira; M. Fukasawa; M. A. Hassan; M. Kawamura; H. Akari; T. Miura; T. Goto; M. Nakai; M. Suleman; M. Isahakia; M. Hayami

  Archives of Virology, Mar. 1993, Peer-reviewed

  
• Identification of Human T Cell Leukemia Virus Type IIb Infection in the Wayu, an Aboriginal Population of Colombia

  Shinji Ijichi; Vladimir Zaninovic; Fidias E. Leon‐S.; Yoshihiko Katahira; Shunro Sonoda; Tomoyuki Miura; Masanori Hayami; William W. Hall

  Japanese Journal of Cancer Research, 1993, Peer-reviewed

  
• Southernmost Carriers of HTLV‐I/II in the World

  Luis Cartier; Fernando Araya; Jose Luis Castillo; Vladimir Zaninovic; Masanori Hayami; Tomoyuki Miura; Joko Imai; Shunro Sonoda; Hiroshi Shiraki; Kanji Miyamoto; Kazuo Tajima

  Japanese Journal of Cancer Research, 1993, Peer-reviewed

  
• Isolation and Genomic Analysis of Human T Lymphotropic Virus Type II from Ghana

  Tatsuhiko Igarashi; Masahiro Yamashita; Tomoyuki Miura; Mubarak Osei-Kwasi; Nana K. Aysi; Hiroshi Shiraki; Takashi Kurimura; Masanori Hayami

  AIDS Research and Human Retroviruses, 1993, Peer-reviewed

  
• ISOLATION AND CHARACTERIZATION OF A HIGHLY DIVERGENT HIV-2[GH-2] - GENERATION OF AN INFECTIOUS MOLECULAR CLONE AND FUNCTIONAL-ANALYSIS OF ITS REV-RESPONSIVE ELEMENT IN RESPONSE TO PRIMATE RETROVIRUS TRANSACTIVATORS (REV AND REX)

  M KAWAMURA; J KATAHIRA; M FUKASAWA; JI SAKURAGI; KI ISHIKAWA; M NAKAI; JAA MINGLE; M OSEIKWASI; VBA NETTY; H AKARI; O HISHIDA; K TOMONAGA; T MIURA; M HAYAMI

  VIROLOGY, Jun. 1992, Peer-reviewed

  
• HTLV-Iの分子系統解析と世界分布

  三浦智行

  臨床とウイルス,20/5,359-366, 1992

  
• BIOLOGICAL CHARACTERIZATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2 MUTANTS IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS

  H AKARI; J SAKURAGI; Y TAKEBE; K TOMONAGA; M KAWAMURA; M FUKASAWA; T MIURA; T SHINJO; M HAYAMI

  ARCHIVES OF VIROLOGY, 1992, Peer-reviewed

  
• ESTABLISHMENT OF A PHYLOGENETIC SURVEY SYSTEM FOR AIDS-RELATED LENTIVIRUSES AND DEMONSTRATION OF A NEW HIV-2 SUBGROUP

  T MIURA; J SAKURAGI; M KAWAMURA; M FUKASAWA; EN MORIYAMA; T GOJOBORI; K ISHIKAWA; JAA MINGLE; VBA NETTEY; H AKARI; M ENAMI; H TSUJIMOTO; M HAYAMI

  AIDS, Dec. 1990, Peer-reviewed

  
• Molecular cloning of feline leukemia provirus genomes integrated in the feline large granular lymphoma cells

  Y. Matsumoto; H. Tsujimoto; M. Fukasawa; Y. Hirota; T. Miura; M. Hayami; R. Goitsuka; K. Ono; A. Hasegawa

  Archives of Virology, Sep. 1990, Peer-reviewed

  
• COMPLEMENTATION OF THE REV GENE MUTATION AMONG HUMAN AND SIMIAN LENTIVIRUSES

  H SAKAI; R SHIBATA; T MIURA; M HAYAMI; K OGAWA; T KIYOMASU; A ISHIMOTO; A ADACHI

  JOURNAL OF VIROLOGY, May 1990, Peer-reviewed

  
• Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIVAGM

  Riri Shibata; Tomoyuki Miura; Masanori Hayami; Koji Ogawa; Hiroyuki Sakai; Takahiro Kiyomasu; Akinori Ishimoto; Akio Adachi

  Journal of Virology, Feb. 1990, Peer-reviewed

  
• CONSTRUCTION AND CHARACTERIZATION OF AN INFECTIOUS DNA CLONE AND OF MUTANTS OF SIMIAN IMMUNODEFICIENCY VIRUS ISOLATED FROM THE AFRICAN-GREEN MONKEY

  R SHIBATA; T MIURA; M HAYAMI; H SAKAI; K OGAWA; T KIYOMASU; A ISHIMOTO; A ADACHI

  JOURNAL OF VIROLOGY, Jan. 1990, Peer-reviewed

  
• 霊長類におけるエイズ関連ウイルス

  三浦智行

  オンコロジア,23/4,70-77, 1990

  
• Mutational analysis of simian immunodefiency virus from African green monkeys and human immunodeficiency virus type 2

  R. Shibata; A. Adachi; H. Sakai; A. Ishimoto; T. Miura; M. Hayami

  Journal of Medical Primatology, 1990, Peer-reviewed

  
• GENOMIC DIVERGENCE OF HIV-2 FROM GHANA

  A HASEGAWA; H TSUJIMOTO; N MAKI; K ISHIKAWA; T MIURA; M FUKASAWA; K MIKI; M HAYAMI

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Dec. 1989, Peer-reviewed

  
• SEQUENCE OF A NOVEL SIMIAN IMMUNODEFICIENCY VIRUS FROM A WILD-CAUGHT AFRICAN MANDRILL

  H TSUJIMOTO; A HASEGAWA; N MAKI; M FUKASAWA; T MIURA; S SPEIDEL; RW COOPER; EN MORIYAMA; T GOJOBORI; M HAYAMI

  NATURE, Oct. 1989, Peer-reviewed

  
• MOLECULAR-CLONING OF A FELINE LEUKEMIA PROVIRUS INTEGRATED ADJACENT TO THE C-MYC GENE IN A FELINE T-CELL LEUKEMIA-CELL LINE AND THE UNIQUE STRUCTURE OF ITS LONG TERMINAL REPEAT

  T MIURA; M SHIBUYA; H TSUJIMOTO; M FUKASAWA; M HAYAMI

  VIROLOGY, Apr. 1989, Peer-reviewed

  
• Genetic analysis and infection of SIV (AGM) and SIV(MND)

  T. Miura; H. Tsujimoto; M. Fukasawa; Y. Ohta; S. Honjo; M. Hayami

  Journal of Medical Primatology, 1989, Peer-reviewed

  
• ISOLATION AND CHARACTERIZATION OF SIMIAN IMMUNODEFICIENCY VIRUS FROM MANDRILLS IN AFRICA AND ITS RELATIONSHIP TO OTHER HUMAN AND SIMIAN IMMUNODEFICIENCY VIRUSES

  H TSUJIMOTO; RW COOPER; T KODAMA; M FUKASAWA; T MIURA; Y OHTA; KI ISHIKAWA; M NAKAI; E FROST; GE ROELANTS; J ROFFI; M HAYAMI

  JOURNAL OF VIROLOGY, Nov. 1988, Peer-reviewed

  
• SEQUENCE OF SIMIAN IMMUNODEFICIENCY VIRUS FROM AFRICAN-GREEN MONKEY, A NEW MEMBER OF THE HIV/SIV GROUP

  M FUKASAWA; T MIURA; A HASEGAWA; S MORIKAWA; H TSUJIMOTO; K MIKI; T KITAMURA; M HAYAMI

  NATURE, Jun. 1988, Peer-reviewed

  
• HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I ISOLATES FROM GABON AND GHANA - COMPARATIVE-ANALYSIS OF PROVIRAL GENOMES

  M FUKASAWA; H TSUJIMOTO; KI ISHIKAWA; T MIURA; B IVANOFF; RW COOPER; E FROST; E DELAPORTE; JAA MINGLE; FC GRANT; M HAYAMI

  VIROLOGY, Dec. 1987, Peer-reviewed

  
• STRUCTURAL ABNORMALITY AND OVER-EXPRESSION OF THE MYC GENE IN FELINE LEUKEMIAS

  T MIURA; H TSUJIMOTO; M FUKASAWA; T KODAMA; M SHIBUYA; A HASEGAWA; M HAYAMI

  INTERNATIONAL JOURNAL OF CANCER, Oct. 1987, Peer-reviewed

  
• INFECTION OF FELINE LYMPHOID-CELLS WITH FELINE LEUKEMIA-VIRUS IN CULTURE

  T KODAMA; T MIURA; H TSUJIMOTO; M HAYAMI

  LEUKEMIA RESEARCH, 1987, Peer-reviewed

  

Misc.

• Development of a hybrid compound of a small molecule CD4 mimic with a polyethylene glycol as an HIV entry inhibitor

  黒田悠貴; 小早川拓也; 辻耕平; 紺野奇重; 大橋南美; 大橋南美; 増田亜美; 三浦裕太郎; 桑田岳夫; 吉村和久; 三浦智行; 原田恵嘉; 松下修三; 玉村啓和

  日本薬学会年会要旨集(Web), 2024

  
• HIV侵入阻害剤を指向したPEG化CD4ミミックの合成

  三浦裕太郎; 小早川拓也; 辻耕平; 紺野奇重; 増田亜美; 大橋南美; 桑田岳夫; 吉村和久; 三浦智行; 原田恵嘉; 松下修三; 玉村啓和

  反応と合成の進歩シンポジウム講演要旨集, 2022

  
• HIV侵入阻害剤を目指したPEG化CD4ミミックの創生

  三浦裕太郎; 小早川拓也; 辻耕平; 紺野奇重; 大橋南美; 増田亜美; 桑田岳夫; 吉村和久; 三浦智行; 原田恵嘉; 松下修三; 玉村啓和

  日本薬学会関東支部大会講演要旨集(CD-ROM), 2022

  
• Bi-functional entry inhibitors sensitize macaque-tropic human immunodeficiency virus type 1 (HIV-1mt) to antibodies generated in HIV-1mt-infected macaques

  Shigeyoshi Harada; Yuta Hikichi; Yohei Seki; Akatsuki Saito; Takeshi Yoshida; Hirotaka Ode; Yasumasa Iwatani; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari; Kazuhisa Yoshimura

  JOURNAL OF MEDICAL PRIMATOLOGY, Oct. 2018

  
• Long-term latency of HIV-1mt infection in cynomolgus macaques is reserved in follicular helper T lymphocytes

  Yohei Seki; Akatsuki Saito; Yorifumi Sato; Shigeyoshi Harada; Hirotaka Ode; Hiroshi Ishii; Takeshi Yoshida; Megumi Murata; Hiroyuki Kangawa; Yuji Watanabe; Yasumasa Iwatani; Kazuhisa Yoshimura; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari

  JOURNAL OF MEDICAL PRIMATOLOGY, Aug. 2017

  
• ヒト免疫不全ウイルス1型(HIV-1)Vprの新規核移行機序を標的とする創薬開発

  間陽子; 石井英樹; 萩原恭二; 鈴木辰徳; 北原玄太; 橋本祥江; 野中瑞穂; 松田剛; 武田英里; 薛光愛; 山本典生; 三浦智行; 鈴木正昭

  日本ウイルス学会学術集会プログラム・抄録集, 2009

  
• Protective effects against simian immunodeficiency virus agm′ (SIV agm) infection in cynomolgus monkeys immunized with′ a recombinant vaccinia virus expressing the SIV agm envelope′ gene.

  Ibuki K.; Ido E.; Funahashi S.; Miura T.; Hayami M.; Shida H.

  Collected papers from Institute for Genetic Medicine Hokkaido University, 1999

  
• Cooperative cellular and humoral immunity may contribute to the efficient control of HIV-1 replication in macaques

  Yohei Seki; Akatsuki Saito; Shigeyoshi Harada; Ayaka Washizaki; Megumi Murata; Yuta Hikichi; Kazuhisa Yoshimura; Hiroshi Ishii; Yorifumi Satou; Islam Mohammad Saiful; Hirotaka Ode; Yasumasa Iwatani; Takeshi Yoshida; Yasuhiro Yasutomi; Tetsuro Matano; Tomoyuki Miura; Hirofumi Akari

  36th Annual Symposium Nonhuman Primate Models for AIDS, 28 Oct. 2018, Peer-reviewed

  
• Molecular characterization of the env gene during transmission of macaque-tropic human immunodeficiency virus type 1 (HIV-1mt)

  Shigeyoshi Harada; Yuta Hikichi; Yohei Seki; Yasumasa Iwatani; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari; Kazuhisa Yoshimura

  36th Annual Symposium Nonhuman Primate Models for AIDS, 28 Oct. 2018, Peer-reviewed

  
• SIV複製制御個体におけるSIV野生型/変異型エピトープ特異的CTL誘導動態の解析

  野村拓志; 野村拓志; 石井洋; 関紗由里; 山本浩之; 寺原和孝; 三浦智行; 俣野哲朗; 俣野哲朗

  日本エイズ学会誌, 20 Nov. 2017

  
• カニクイザルにおけるHIV‐1mt長期潜伏感染の解析

  関洋平; 齊藤暁; 佐藤賢文; 原田恵嘉; 吉村和久; 大出裕高; 岩谷靖雅; 石井洋; SAIFULISLAM M; 芳田剛; 村田めぐみ; 鷲崎彩夏; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文; 明里宏文

  日本エイズ学会誌, 20 Nov. 2017

  
• SIV感染サルをモデルとした中和抗体誘導メカニズムの解析

  桑田岳夫; 佐野雅人; 松岡佐織; 俣野哲朗; 関洋平; 明里宏文; 明里宏文; 三浦智行; 松下修三

  日本エイズ学会誌, 20 Nov. 2017

  
• 伝播により変異を蓄積したSIVの感染免疫動態に関する研究

  関紗由里; 野村拓志; 野村拓志; 西澤雅子; 石井洋; 三浦智行; 俣野哲朗; 俣野哲朗; 俣野哲朗

  日本エイズ学会誌, 20 Nov. 2017

  
• Characterization of Long-term Latency of HIV-1mt Infection in Cynomolgus Macaques

  Seki Y; Saito A; Satou Y; Harada S; Yoshimura K; Ode H; Iwatani Y; Ishii H; Saiful IM; Yoshida T; Murata M; Washizaki A; Yasutomi Y; Matano T; Miura T; Akari H

  The 31th Annual Meeting of the Japanese Society for AIDS Research, Nov. 2017, Peer-reviewed

  
• Mechanism of neutralizing antibody induction in SIV-infected macaques

  Kuwata T; Sano M; Matsuoka S; Matano T; Seki Y; Akari H; Miura T; Matsushita S

  The 31th Annual Meeting of the Japanese Society for AIDS Research, Nov. 2017, Peer-reviewed

  
• Neutralizing antibody induction and changes in viral env sequences in the chronic phase of SIVsmH635FC infection

  Sano M; Kuwata T; Matsuoka S; Akari H; Miura T; Matano T

  65th Annual Meeting of the Japanese Society for Virology, Oct. 2017, Peer-reviewed

  
• Comparison of plasma neutralizing antibodies in two macaque-tropic HIV-1 infected macaques that were different response by CD8 depletion

  Shigeyoshi Harada; Yohei Seki; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari; Kazuhisa Yoshimura

  JOURNAL OF MEDICAL PRIMATOLOGY, Aug. 2017

  
• サル骨髄造血幹細胞移植マウスへのサル免疫不全ウイルス(SIV)感染実験

  関根将; 藤田悠平; 陣野萌恵; 三浦智行; 伊吹謙太郎

  臨床検査学教育, 01 Mar. 2017

  
• iPS細胞由来再生T細胞の臨床応用に向けた霊長類前臨床モデルの開発

  三宅康行; 入口翔一; 三浦智行; 立川愛; 上田樹; 上田樹; 田谷かほる; 田谷かほる; 今井映里; 石井洋; 尾上浩隆; 寺倉精太郎; 俣野哲朗; 金子新

  再生医療, 01 Feb. 2017

  
• Bi-functional entry inhibitors sensitize macaque-tropic human immunodeficiency virus type 1 (HIV-1mt) to antibodies generated in HIV-1mt-infected macaques

  Shigeyoshi Harada; Yuta Hikichi; Yohei Seki; Akatsuki Saito; Takeshi Yoshida; Hirotake Ode; Yasumasa Iwatani; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari; Kazuhisa Yoshimura

  35th Annual Symposium on Nonhuman Primate Models for AIDS, 2017, Peer-reviewed

  
• HIV‐1ワクチン開発とその課題

  志田壽利; 加藤誠一; 加藤誠一; 保富康宏; 松尾和浩; 三浦智行; 五十嵐樹彦; 張険峰; 井上誠; 成瀬妙子; 木村彰方

  MHC (Web), 15 Oct. 2016

  
• R5-tropic HIV-1 infection leads to long-term latency in cynomolgus macaques

  Hirofumi Akari; Yohei Seki; Akatsuki Saito; Yorifumi Satou; Shigeyoshi Harada; Kazuhisa Yoshimura; Hirotaka Ode; Yasumasa Iwatani; Takeshi Yoshida; Megumi Murata; Yuji Watanabe; Yasuhiro Yasutomi; Tetsuro Matano; Tomoyuki Miura

  第64回日本ウイルス学会学術集会, Oct. 2016, Peer-reviewed

  
• HIV‐1感染症の機能的治療におけるウィルスリザーバーサイズの意義

  石田裕樹; 三浦智行

  東京生化学研究会助成研究報告集, 30 Sep. 2016

  
• サル免疫細胞を持つマウス(サル化マウス)へのサル免疫不全ウイルス(SIV)感染実験

  関根将; 藤田悠平; 陣野萌恵; 三浦智行; 伊吹謙太郎

  日本獣医学会学術集会講演要旨集, 30 Aug. 2016

  
• サルレトロウイルス5型感染によるニホンザル血小板減少症

  吉川禄助; 吉川禄助; 坂口翔一; 坂口翔一; 中川草; 中村紳一朗; 阪脇廣美; 兼子明久; 三浦智行; 鈴木樹理; 岡本宗裕; 宮沢孝幸

  日本獣医学会学術集会講演要旨集, 30 Aug. 2016

  
• サルレトロウイルス5型(SRV‐5)のニホンザルへの感染実験

  岡本宗裕; 吉川禄助; 阪脇廣美; 鈴木樹理; 坂口翔一; 兼子明久; 中村紳一朗; 三浦智行; 宮沢孝幸

  霊長類研究, 20 Jun. 2016

  
• Long-term Latency of HIV-1mt Infection in Cynomolgus Macaques is Reserved in Follicular Helper T Lymphocytes

  Yohei Seki; Akatsuki Saito; Yorifumi Satou; Shigeyoshi Harada; Hirotaka Ode; Hiroshi Ishii; Takeshi Yoshida; Megumi Murata; Hiroyuki Kangawa; Yuji Watanabe; Yasumasa Iwatani; Kazuhisa Yoshimura; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari

  34th Annual Symposium on Nonhuman Primate Models for AIDS, 2016, Peer-reviewed

  
• 薬物動態の改善を目指したCD4ミミック型HIV‐1侵入阻害薬リードに関する研究

  水口貴章; 原田恵嘉; 三浦智行; 苛原優; 小谷みさと; 石田有佑; 山田裕子; 山田裕子; 大橋南美; 野村渉; 松下修三; 吉村和久; 玉村啓和

  日本薬学会年会要旨集(CD-ROM), 2016

  
• R5指向性HIV‐1mt感染カニクイザルによる新規エリートコントローラーモデルの開発

  関洋平; 齊藤暁; 芳田剛; 佐藤賢文; 原田恵嘉; 吉村和久; 渡部祐司; 岩谷靖雅; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文; 明里宏文

  日本エイズ学会誌, 20 Nov. 2015

  
• 新規CD4ミミックの創製と薬物動態解析

  石田有佑; 水口貴章; 原田恵嘉; 三浦智行; 小谷みさと; 山田裕子; 山田裕子; 苛原優; 野村渉; 松下修三; 吉村和久; 玉村啓和

  日本エイズ学会誌, 20 Nov. 2015

  
• CD163陽性細胞は高病原性SHIV感染サルの治療下におけるウイルスRNA陽性細胞である

  渡部祐司; 渡部祐司; 岩見真吾; 松浦嘉奈子; 森ひろみ; 日紫喜隆行; 三浦智行; 明星宏文; 五十嵐樹彦

  日本エイズ学会誌, 20 Nov. 2015

  
• カテコール誘導体を基盤とした新規CD4ミミックの創製と薬物動態解析

  石田有佑; 水口貴章; 原田恵嘉; 三浦智行; 小谷みさと; 山田裕子; 山田裕子; 苛原優; 野村渉; 松下修三; 吉村和久; 玉村啓和

  メディシナルケミストリーシンポジウム講演要旨集, 01 Nov. 2015

  
• HIV外被タンパク質gp120を標的とするmono‐cyclohexcyl型低分子CD4ミミックの創製研究

  小谷みさと; 苛原優; 原田恵嘉; 大橋南美; 山田裕子; 山田裕子; 水口貴章; 三浦智行; 野村渉; 松下修三; 吉村和久; 玉村啓和

  日本薬学会関東支部大会講演要旨集, 07 Sep. 2015

  
• 霊長類モデルを用いたHIV感染症の予防・治療法開発

  三浦智行

  日本実験動物学会総会講演要旨集, 30 Apr. 2015

  
• SIVが感染可能なサル免疫細胞を持つマウスの作製

  橋本隼; 藤田悠平; 三浦智行; 伊吹謙太郎

  日本実験動物学会総会講演要旨集, 30 Apr. 2015

  
• サル指向性HIV‐1のin vivoにおける増殖効率を上昇させる要因

  関洋平; 芳田剛; 齊藤暁; 松岡和弘; 大出裕高; 岩谷靖雅; 保富康宏; 俣野哲朗; 三浦智行; 杉浦亙; 明里宏文

  日本実験動物学会総会講演要旨集, 30 Apr. 2015

  
• 高病原性HIV感染サルにおいてウイルス感染CD163陽性マクロファージは様々な半減期を持つ集団から構成され、最も半減期の長い集団は多剤併用療法下のリザーバーと成り得る

  渡部祐司; 岩見真吾; 森ひろみ; 松浦嘉奈子; 日紫喜隆行; 三浦智行; 明里宏文; 五十嵐樹彦

  第63回日本ウイルス学会学術集会, 2015, Peer-reviewed

  
• 高病原性SHIV感染サルにおいて、ART治療下で観察されたウイルスの減衰に関する検証

  渡部祐司; 岩見真吾; 森ひろみ; 松浦嘉奈子; 日紫喜隆行; 三浦智行; 明里宏文; 五十嵐樹彦

  第29回日本エイズ学会学術集会, 2015, Peer-reviewed

  
• HIV-1mt感染カニクイザルによる新規エリートコントローラーモデル

  関洋平; 齊藤暁; 芳田剛; 佐藤賢文; 原田恵嘉; 吉村和久; 渡部祐司; 岩谷靖雅; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文

  第63回日本ウイルス学会学術集会, 2015, Peer-reviewed

  
• Detection of potency and breadth of HIV-1 Neutralizing Antibodies in macaque-tropic HIV-1 infected cynomolgus monkeys using novel test panel viruses

  Shigeyoshi Harada; Akatsuki Saito; Takeshi Yoshida; Yohei Seki; Yuji Watanabe; Yasumasa Iwatani; Yasuhiro Yasutomi; Tomoyuki Miura; Tetsuro Matano; Hirofumi Akari; Kazuhisa Yoshimura

  33rd Annual Symposium on NHP Models for AIDS, 2015, Peer-reviewed

  
• Novel elite controller model by HIV-1mt-infected cynomolgus macaques

  Yohei Seki; Akatsuki Saito; Takeshi Yoshida; Yorifumi Satou; Shigeyoshi Harada; Kazuhisa Yoshimura; Yuji Watanabe; Yasumasa Iwatani; Yasuhiro Yasutomi; Tetsuro Matano; Tomoyuki Miura; Hirofumi Akari

  33rd Annual Symposium on NHP Models for AIDS, 2015, Peer-reviewed

  
• HIVの潜伏・再活性化および慢性的免疫活性化を左右する細胞因子・免疫応答の解明とその制御 粘膜・リンパ組織の抗原提示細胞への感染様式の解明

  五十嵐樹彦; 三浦智行

  HIVの潜伏・再活性化および慢性的免疫活性化を左右する細胞因子・免疫応答の解明とその制御 平成26年度 総括・分担研究報告書, 2015

  
• Bromocriptineによる抗デングウイルス活性機構の解析

  加藤文博; 加藤文博; 石田裕樹; 大石真也; 藤井信孝; 田島茂; 高崎智彦; 三浦智行; 五十嵐樹彦; 日紫喜隆行; 日紫喜隆行

  日本生化学会大会(Web), 2015

  
• 中和抗体を用いたHIV感染症の「機能的治癒」をめざす新規治療法の開発 NBD誘導体の動物モデルを用いたin vivo試験

  五十嵐樹彦; 三浦智行

  中和抗体を用いたHIV感染症の「機能的治癒」をめざす新規治療法の開発 平成26年度総括・分担研究報告書, 2015

  
• 抗HIV薬投与下の治療ワクチン接種により誘導されるCD8陽性T細胞のSIV複製抑制能の解析

  中村碧; 高原悠佑; 松岡佐織; 團塚愛; 三浦智行; 小柳義夫; 成瀬妙子; 木村彰方; 俣野哲朗

  日本エイズ学会誌, 20 Nov. 2014

  
• サル指向性HIV‐1の感染個体における増殖効率を上昇させる要因

  芳田剛; 齊藤暁; 松岡和弘; 大出裕高; 岩谷靖雅; 保富康宏; 俣野哲朗; 杉浦亙; 三浦智行; 明里宏文

  日本エイズ学会誌, 20 Nov. 2014

  
• bromocriptineによる抗デングウイルス活性機構の解析

  加藤文博; 石田裕樹; 大石真也; 藤井信孝; 三浦智行; 五十嵐樹彦; 日紫喜隆行

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• 抗デングウイルス活性を有する生薬由来成分の探索と性状解析

  日紫喜隆行; 加藤文博; 三浦智行; 五十嵐樹彦

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• 新規CCR5指向性SHIVのサルへの順化と中和抗体抵抗性の解析

  三浦智行; 米田舞; 大附寛幸; 松下修三; 日紫喜隆行; 五十嵐樹彦

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• SIVの持続感染・伝播における変異蓄積に関する研究

  関紗由里; 野村拓志; 西澤雅子; 横山勝; 佐藤裕徳; 團塚愛; 三浦智行; 小柳義夫; 俣野哲朗

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• In vivoにおけるサル指向性HIV‐1の増殖効率を上昇させる要因

  芳田剛; 齊藤暁; 松岡和弘; 大出裕高; 岩谷靖雅; 杉浦亙; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• 高病原性SHIV感染サルにおける感染マクロファージは感染リンパ球と同程度の半減期を示す

  渡部祐司; 岩見真吾; 森ひろみ; 石田裕樹; 日紫喜隆行; 三浦智行; 五十嵐樹彦

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2014

  
• アカゲザルの摂食率向上に対する給餌の工夫

  團塚愛; 井澤菜摘; 三浦智行

  日本実験動物学会総会講演要旨集, 01 May 2014

  
• サル用大型アイソレーター内部と飼育室との温湿度の比較

  團塚愛; 井澤菜摘; 三浦智行

  日本実験動物学会総会講演要旨集, 01 May 2014

  
• 動物由来感染症の対応に関する研究 ニホンザル血小板減少症の原因となるSRVのウイルス学的解析

  三浦智行; 宮沢孝幸

  動物由来感染症の対応に関する研究 平成25年度 総括・分担研究報告書, 2014

  
• 新規CCR5指向性かつ中和抵抗性SHIVクローンの作製および解析

  米田舞; 大附寛幸; 松下修三; 三浦智行

  日本エイズ学会誌, 20 Nov. 2013

  
• CCR5指向性を示す新規サル指向性HIV‐1はサル個体に持続感染する

  齊藤暁; 大附寛幸; 東濃篤徳; 鈴木紗織; 松田健太; 高橋尚史; 松岡佐織; 岩谷靖雅; 杉浦亙; 野間口雅子; 足立昭夫; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文

  日本エイズ学会誌, 20 Nov. 2013

  
• 抗V3抗体および低分子CD4ミミック曝露後投与によるアカゲザルでのSHIV複製抑制

  大附寛幸; 丸田泰広; 橋本知恵; 鳴海哲夫; 廣田雄樹; 原田恵嘉; 三浦智行; 吉村和久; 玉村啓和; 松下修三; 五十嵐樹彦

  日本エイズ学会誌, 20 Nov. 2013

  
• 分泌型ルシフェラーゼ遺伝子を有するデングウイルス1型レプリコンの構築

  加藤文博; 小林剛; 三浦智行; 五十嵐樹彦; 日紫喜隆行

  日本ウイルス学会学術集会プログラム・抄録集, 29 Oct. 2013

  
• CCR5指向性を示す新規サル指向性HIV‐1はサル個体に持続感染する

  齊藤暁; 大附寛幸; 東濃篤徳; 鈴木紗織; 松田健太; 高橋尚史; 松岡佐織; 岩谷靖雅; 杉浦亙; 野間口雅子; 足立昭夫; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文

  日本ウイルス学会学術集会プログラム・抄録集, 29 Oct. 2013

  
• フィリピンカニクイザルにおけるデングウイルス自然感染

  石田裕樹; 加藤文博; 川岸崇裕; 小林剛; 日紫喜隆行; 三浦智行; 五十嵐樹彦

  日本ウイルス学会学術集会プログラム・抄録集, 29 Oct. 2013

  
• CCR5指向性サブタイプCエンベロープを持つサル指向性HIV‐1のブタオザルにおける複製

  大附寛幸; 五十嵐樹彦; 三浦智行

  日本ウイルス学会学術集会プログラム・抄録集, 29 Oct. 2013

  
• サルエイズモデルにおける抗HIV薬投与下のCTL誘導治療ワクチン接種によるSIV増殖抑制能の増強効果の解析

  中村碧; 高原悠佑; 松岡佐織; 三浦智行; 小柳義夫; 成瀬妙子; 木村彰方; 俣野哲朗

  日本ウイルス学会学術集会プログラム・抄録集, 29 Oct. 2013

  
• サル免疫細胞を体内に持つマウス作成の試み

  西脇和摩; 溝越祐志; 三浦智行; 伊吹謙太郎

  日本獣医学会学術集会講演要旨集, 30 Aug. 2013

  
• ウイルスの標的細胞指向性はサル指向性HIV‐1の増殖に影響するか?

  齊藤暁; 大附寛幸; 東濃篤徳; 鈴木紗織; 松田健太; 高橋尚史; 松岡佐織; 岩谷靖雅; 杉浦亙; 保富康宏; 俣野哲朗; 三浦智行; 明里宏文

  日本獣医学会学術集会講演要旨集, 30 Aug. 2013

  
• 感染性分子クローン由来サルレトロウイルス4型実験感染ニホンザルにおけるウイルスの体内動態

  坂口翔一; 吉川禄助; 岡本宗裕; 明星宏文; 齊藤暁; 佐藤英次; 安永純一郎; 三浦智行; 宮沢孝幸

  日本獣医学会学術集会講演要旨集, 30 Aug. 2013

  
• 新規CCR5指向性SHIVのサルへの順化と中和抵抗性の解析

  三浦智行; 米田舞; 大附寛幸; 一瀬裕太郎; 松田健太; 松下修三; 五十嵐樹彦

  日本獣医学会学術集会講演要旨集, 04 Mar. 2013

  
• 京都大学霊長類研究所サル施設でサルレトロウイルス４型に感染したニホンザル由来感染性分子クローンを用いた感染実験

  坂口翔一; 吉川禄助; 岡本宗裕; 明里宏文; 齊藤暁; 佐藤英次; 安永純一郎; 三浦智行; 宮沢孝幸

  第19回日本野生動物学会大会, 2013, Peer-reviewed

  
• 感染性分子クローン由来ウイルスを用いたニホンザル血小板減少症の病態解析

  坂口翔一; 吉川禄助; 岡本宗裕; 明里宏文; 齊藤暁; 佐藤英次; 安永純一郎; 三浦智行; 宮沢孝幸

  日本野生動物医学会大会・講演要旨集, 2013

  
• HIV外被タンパク質gp120を標的としたインドール型低分子CD4ミミックの創製

  廣田雄樹; 鳴海哲夫; 橋本知恵; 吉村和久; 原田恵嘉; 大附寛幸; 三浦智行; 五十嵐樹彦; 相川春夫; 野村渉; 松下修三; 玉村啓和

  日本薬学会年会要旨集(CD-ROM), 2013

  
• 新規CCR5 指向性SHIV のサルヘの順化と中和抵抗性の解析

  米田舞; 大附寛幸; 一瀬裕太郎; 松田健太; 松下修三; 五十嵐樹彦; 三浦智行

  第155 回日本獣医学会、東京、2013 年3 月28-30日, 2013, Peer-reviewed

  
• サルエイズモデルにおける抗HIV薬投与下のCTL誘導治療ワクチン接種効果の解析

  中村碧; 高原悠佑; 松岡佐織; 阪脇廣美; 三浦智行; 五十嵐樹彦; 小柳義夫; 成瀬妙子; 木村彰方; 俣野哲朗

  日本エイズ学会誌, 20 Nov. 2012

  
• HIV外被タンパク質gp120を標的とするインドール型低分子CD4ミミックの創製研究

  廣田雄樹; 鳴海哲夫; 橋本知恵; 吉村和久; 原田恵嘉; 大附寛幸; 三浦智行; 五十嵐樹彦; 相川春夫; 野村渉; 松下修三; 玉村啓和

  日本エイズ学会誌, 20 Nov. 2012

  
• 抗デングウイルス活性を有する化合物の探索および作用機序の解析

  KATO FUMIHIRO; KAWAGISHI TAKAHIRO; HYUGA RYOSUKE; OISHI SHIN'YA; FUJII NOBUTAKA; MIURA TOMOYUKI; KOBAYASHI TAKESHI; IGARASHI TATSUHIKO

  日本ウイルス学会学術集会プログラム・抄録集, 31 Oct. 2012

  
• Generation of monkey-tropic human immunodeficiency virus strains carrying a variety of CCR5-utilizing env genes from HIV- 1 subtype C clinical isolates through intracellular homologous recombination

  Hiroyuki Otsuki; Takeshi Kobayashi; Tatsuhiko Igarashi; Tomoyuki Miura

  19th East Asia Joint Symposium on Biomedical Research, Seoul, Korea, 2012.8.22.25, 2012, Peer-reviewed

  
• ニホンザル血小板減少症の原因ウイルスの探索

  吉川禄助; 佐藤英次; 岡本宗裕; 鈴木樹理; 吉田友教; 明里宏文; 三浦智行; 宮沢孝幸

  第153 回日本獣医学会学術集会, 埼玉, 2012 年3 月27-29 日, 2012, Peer-reviewed

  
• HIV 外被タンパク質gp120 を標的とするインドール型低分子CD4ミミックの創製研究

  廣田雄樹; 鳴海哲夫; 橋本知恵; 吉村和久; 原田恵嘉; 大附寛幸; 三浦智行; 五十嵐樹彦; 相川春夫; 野村渉; 松下修三; 玉村啓和

  第26 回日本エイズ学会、神奈川、2012年11月24-26 日, 2012, Peer-reviewed

  
• サルエイズモデルにおける抗HIV 薬投与下のCTL 誘導治療ワクチン接種効果の解析

  中村碧; 高原悠佑; 松岡佐織; 阪脇房美; 三浦智行; 五十嵐樹彦; 小枷義夫; 成瀬妙子; 木村彰方; 俣野哲朗

  第26回日本エイズ学会、神奈川、2012 年11 月24-26, 2012, Peer-reviewed

  
• 細胞内相同組換えを利用したCCR5 指向性サブタイプC HIV-1 由来env を持つサル指向性HIV-1 の作出

  大附寛幸; 一瀬裕太郎; 小林剛; 五十嵐樹彦; 三浦智行

  第26 回日本エイズ学会、神奈川、2012 年11月24-26日, 2012, Peer-reviewed

  
• SHIV 感染アカゲザルにおいて病原性を決定づけるウイルス感染動態の探索―数理モデルによるデータ解析の視点から―

  岩見真吾; Rob de Boer; 三浦智行; 西村隹哲; 五十嵐樹彦

  第26 回日本エイズ学会、神奈川、2012 年11 月24-26 日, 2012, Peer-reviewed

  
• 高病原性SHIV 感染 サルにおける感染マクロファージの半減期の推定

  渡部祐司; 岩見真吾; 西山由利子; 森ひろみ; 三浦智行; 五十嵐樹彦

  第60 回日本ウイルス学会学術集会、大阪、2012 年11 月13 日-15日, 2012, Peer-reviewed

  
• サルに順化したCCR5 指向性SHIV-MK38 の中和抗体に対する抵抗性

  米田舞; 一瀬裕太郎; 大附寛幸; 松田健太; 松下修三; 五十嵐樹彦; 三浦智行

  第60 回日本ウイルス学 会、大阪、2012 年11 月13-15 日, 2012, Peer-reviewed

  
• シベリア型ダニ媒介性脳炎ウイルスI R 9 9-2 f 7 株の感染性cDNA クローンの構築

  川岸崇裕; 加藤文博; 日向亮輔; 三浦智行; 小林剛; 五十嵐樹彦

  第60 回日本ウイルス学会学術集会、大阪、2012 年11 月13-15 日, 2012, Peer-reviewed

  
• 中和感受性を増強する薬剤による抗HIV-1治療戦略に向け た新規SHIV/ アカゲザル評価モデルの開発

  大附寛幸; 一瀬裕太郎; 小林剛; 原田恵嘉; 吉村和久; 鳴海哲夫; 玉村啓和; 松下修三; 五十嵐樹彦; 三浦智行

  第60 回日本ウイルス学会、大阪、2012 年11 月13-15日, 2012, Peer-reviewed

  
• 培養細胞実験と数理モデルによるウイルス感染動態の定量化―ウイルス病原性の解明への応用―

  岩見真吾; de Boer Rob; 五十嵐樹彦; 三浦智行

  第60 回日本ウイルス学会、大阪、2012 年11 月13-15 日, 2012, Peer-reviewed

  
• 抗ダンプウイルス活性を有するかご物の探索および作用機序の解析

  藤文博; 川岸崇裕; 日向亮輔; 大石真也; 藤井信孝; 三浦智行; 小林剛; 五十嵐樹彦

  第60 回日本 ウイルス学会学術集会、大阪、2012 年11 月13 日, 2012, Peer-reviewed

  
• フィリピンカニクイザルにおける デングウイルス感染状況

  加藤文博; 川岸崇裕; 小林剛; 三浦智行; 五十嵐樹彦

  第19回トガ・フラビ・ペスチウイルス研究会、大阪、2012年11月12日, 2012, Peer-reviewed

  
• ダニ媒介性脳炎ウイルスCapsid 欠損レプリコンの構築及びSingle-round infectious system の開発

  日向亮輔; 川岸崇裕; 加藤文博; 好井健太朗; 高島郁夫; 三浦智行; 小林剛; 五十嵐樹彦

  第47 回日本脳炎ウイルス生態学研究会、熊本、2012年 5 月25 日-26 日, 2012, Peer-reviewed

  
• 新規相同組換え技術による組換えダニ媒介性脳炎ウイルスの構築

  川岸 崇裕; 日向 亮輔; 加藤 文博; 好井 健太朗; 高島 郁夫; 三浦 智行; 五十嵐 樹彦; 小林 剛

  日本獣医学会学術集会講演要旨集, Aug. 2011, Peer-reviewed

  
• Quantification system of viral dynamics in vitro -the dynamics of SHIV on HSC-F-.

  Iwami S; Beauchemin C; Tada T; Igarashi T; Miura T

  8th ESMTB Conference. Poland. June 28-July 2. 2011., 2011, Peer-reviewed

  
• 高病原性STV に対する組換えBCG と弱毒ワクシニア(m8 A)エイズワクチン の防御効果

  張険峰; 五十嵐樹彦; 松尾和浩; 堀端重男; 横溝香里; 三浦智行; 大橋貴; 山本直樹; 志田昌利

  第25 回日本エイズ学会学術集会、東京、2011 年11 月30 日-12月2 日, 2011, Peer-reviewed

  
• サルエイズモデル感染初期におけるMHC クラスT ハプロタイ プ別のCTL 反応優位パターンの解析

  中村碧; 高原悠佑; 阪脇廣美; 堀池麻里子; 三浦智行; 五十嵐樹彦; 成瀬妙子; 木村彰方; 俣野哲朗; 松岡沙織

  第25 回日本エイズ学会学術集会、東京、2011 年11 月30 日-12月2 日, 2011, Peer-reviewed

  
• 中和抵抗性 のサル/ヒト免疫不全ウイルスの作製とin vitro における立体構造変化誘導剤に よる中和感受性増強効果の評価

  大附寛幸; 三浦智行; 小林剛; 吉村和久; 玉村啓和; 松下修三; 五十嵐樹彦

  第25 回日本エイズ学会学術集会、東京、2011 年 11 月30 日-12月2 日, 2011, Peer-reviewed

  
• フラビウイルスにおける宿主DNA 修復機構を用いた新規リバースジェネティクス系の開発

  日向亮輔; 川岸崇裕; 加藤文博; 好井健太朗; 高島郁夫; 三浦智行; 五十嵐樹彦; 小林剛

  第18回トガ・フラビ・ペスチウイルス研究会、東京、2011 年11 月11日, 2011, Peer-reviewed

  
• ダニ媒介性脳炎ウイルスIR99 株の感染性cDNA クローンの構築

  川岸崇裕; 日向亮輔; 加藤文博; 三浦智行; 五十嵐樹彦; 小林剛

  第18回トガ・フラビ・ペスチウイルス研究会、東京、2011 年11 月11日, 2011, Peer-reviewed

  
• 抗デングウイルス活性を有する薬剤の探索

  加藤文博; 日向亮輔; 川岸崇裕; 大石真也; 藤井信孝; 三浦智行; 五十嵐樹彦; 小林剛

  第18回トガ・フラビ・ペスチウイルス研究会、東京、2011年11月11日, 2011, Peer-reviewed

  
• Contribution of long-lived productively infected cells in SIV infection.

  S. Iwami; M. Horiike; T. Miura; T. Igarashi

  SIAM Conference on Life Science, Pittsburgh, Pennsylvania, July 12-15, 2010, 2010, Peer-reviewed

  
• 相同組換えによって作製した新規サル指向性ヒト免疫不全ウイルスの遺伝子解析

  中村仁美; 大附寛幸; 松田健太; 小林剛; 五十嵐樹彦; 三浦智行

  第24 回日本エイズ学会学術集会、東京、2010年11月24-26 日, 2010, Peer-reviewed

  
• 講演「霊長類エイズモデル研究の新展開」

  三浦智行

  第6 回霊長類医科学フォー ラム，つくば市、 2010 年11 月18 日, 2010, Peer-reviewed

  
• 新規組換え技術によるCCR5 指向 性clade C HIV-1 株のenv 領域を持ったSHIV の作製

  藤田泰久; 大附寛幸; 小林剛; 三浦智行; 五十嵐樹彦

  第24 回日本エイズ学会学術集 会、東京、2010 年11 月24-26 日, 2010, Peer-reviewed

  
• SIV 感染アカゲザルによるHAART 治療 モデルのデータ解析

  岩見真吾; 堀池麻里子; 三浦智行; 五十嵐樹彦

  第24 回日本エイズ学会学術集会、東京、2010 年11 月24-26 日, 2010, Peer-reviewed

  
• 多剤併用療法実施下のサルエイズモデルにおけるリンパ節内でのウイルス新規感染の可唐腫

  堀池麻里子; 松山めぐみ; 安井美加; 小林剛; 三浦智行; 五十嵐樹彦

  第58 回 日本ウイルス学会学術集会、徳島、2010 年11 月7-9 日, 2010, Peer-reviewed

  
• サルエイズモデルにおけるHAART 実施前後のCTL 反応の比較

  高原悠佑; 松岡佐織; 石井洋; 堀池麻里子; 三浦智行; 五十嵐樹彦; 俣野哲朗

  第58 回日本ウイルス学会学術集会、徳島、2010 年11 月7-9 日、, 2010, Peer-reviewed

  
• 新規組換え技術によるR5 指向性clade C env を持つサル指向性HIV-1 の創出

  大附寛幸; 藤田泰久; 小林剛; 三浦智行; 五十嵐樹彦

  第58 回日本ウイルス学会学術集会、徳島、 2010 年11 月7 日-9 日, 2010, Peer-reviewed

  
• 数理モデルによるウイルス感染力推定法の開発

  岩見真吾; 多田哲子; 五十嵐樹彦; 三浦智行

  第58 回日本ウイルス学会学術集会、徳島、2010 年11 月7 日-9 日, 2010, Peer-reviewed

  
• SIV 感染アカゲザルによるHAART 治療モデルのデータ解析とその理論

  岩見真吾; 堀池麻里子; 三浦智行; 稲葉寿; 守田智; 五十嵐樹彦

  第20 回日本数理生物学会、札幌、 2010 年9 月14 日, 2010, Peer-reviewed

  
• 相同組換えによって作製した新規サル/ ヒト免疫不全 ウイルスの遺伝子解析

  中村仁美; 五十嵐樹彦; 三浦智行

  第19 回サル疾病ワークショップ、東京、2010 年7 月3 日, 2010, Peer-reviewed

  
• リポペプチド: エイズ免疫の新たな標的分子

  森田大輔; 堀池麻理子; 三浦智行; 森直樹; 五十嵐樹彦; 杉田昌彦

  第13回京都免疫ワークショップ学術集会 大阪2010 年2 月13日, 2010, Peer-reviewed

  
• Experimental and theoretical perspective of SHIV pathogenesis

  Iwami S; Miura T; Takeuchi Y

  The Second International Conference on Infectious Disease Dynamics, Athens, Greece, Dec.2-4, 2009., 2009, Peer-reviewed

  
• 変異株の固定確立-確率過程によるモデリング-

  岩見慎吾; 佐々木顕; 三浦智行

  第23 回 日本エイズ学会学術集会,2009 年11 月26-28 日, 名古屋, 2009, Peer-reviewed

  
• ヒト免疫不全にウイルス1 型(HIV-1)アクセサリータンパク質Vpr 検出用試薬の開発

  石井英樹; 鈴木辰徳; 松田剛; 武田英里; 三浦智行; 間陽子; 鈴木正昭

  第57 回日本ウイルス学会学術集会,2009 年10 月25-27 日, 東京, 2009, Peer-reviewed

  
• ヒト免疫不全ウイルスT 型(HIV-1) Vpr の新規核移行機序を標的とする創薬開発

  間陽子; 石井英樹; 萩原恭二; 鈴木辰徳; 北原玄太; 橋本祥江; 野中瑞穂; 松田剛; 武田 英里; 薛光愛; 山本典生; 三浦智行; 鈴木正昭

  第57 回日本ウイルス学会学術集会、2009 年10月25-27 日、東京, 2009, Peer-reviewed

  
• ビルマ産アカゲザルSTV 感染により誘導されるCTL エピトープの探索

  高原悠侑; 武内寛明; 石井洋; 高橋尚史; 三浦智行; 五十嵐樹彦; 俣野哲朗

  第57 回日本ウイルス学会学術集会、2009 年10月25-27 日、東京, 2009, Peer-reviewed

  
• 抗HIV ワクチン評価に有用なR5 指向性SHTV の作製

  松田健太; 稲葉一寿; 深澤嘉伯; 伊吹謙太郎; 松山めぐみ; 堀池麻里子; 速水正憲; 五十嵐樹彦; 三浦智行

  第57 回 日本ウイルス学会学術集会、2009 年10月25-27 日、東京, 2009, Peer-reviewed

  
• 実験データによるSHTV 感染力推定理論の開発

  岩見真吾; 三浦智行; 竹内康博

  第19回 日本数理生物学会年会、2009 年9 月9-11 日、東京, 2009, Peer-reviewed

  
• ATDS ワクチン開発への理論的介入-SHTV 感染実験と数理 モデル-

  岩見真吾; 三浦智行; 竹内康博

  第19回日本数理生物学会年会、2009 年9 月9-11 日、東京, 2009, Peer-reviewed

  
• 霊長類エイズモデル研究の新展開

  三浦智行

  第19 回日本数理生物学会年会、2009 年9 月9-11日、東京, 2009, Peer-reviewed

  
• HIV-1 由来のpo1 遺伝 子を持つSHIV-prti のアカゲザルin vivo 継代による感染増殖能の増加

  井戸栄治; 石松美沙; 三浦智行; 多田哲子; 多田秀子; 伊吹謙太郎

  第22回日本工 イズ学会学術会総会、大阪、11 月26-28 日、2008, 26 Nov. 2008, Peer-reviewed

  
• HIV-1 の逆写酵素とインテグラーゼ遺伝子を持つSHIV-rt 目友アカゲザルに持続感染しエイズ様症状を引 き起こす

  井戸栄治; 石松美沙; 三浦智行; 多田哲子; 多田秀子; 伊吹謙太郎

  第56 回日本ウイルス学会学術、岡山、10 月26-28 日、2008, 26 Oct. 2008, Peer-reviewed

  
• グリア細胞におけるネコ免疫不全ウイルスの受容体スイッチング

  石川美恵子; 馬場健司; 庄嶋貴之; 下島昌幸; 三浦智行; 宮沢孝幸

  日本ウイルス学会学術集会プログラム・抄録集, 01 Oct. 2008

  
• アカゲザル血液中CD4+CD8+double positive T細胞におけるCCR5発現とサル免疫不全ウイルス感受性

  松本祐介; 芳賀猛; 三浦智行

  日本ウイルス学会学術集会プログラム・抄録集, 01 Oct. 2008

  
• アカゲザルCD4+CD8+double positiveT細胞のCCR5発現とサル免疫不全ウイルス感受性

  松本祐介; 芳賀猛; 後藤義孝; 三浦智行

  日本獣医学会学術集会講演要旨集, 05 Sep. 2008

  
• 新規CCR5 指向性SHTV の作製とアカゲザルへの順化

  松田健太; 稲葉一寿; 伊吹謙太郎; 深澤嘉伯; 松山めぐみ; 斉藤尚紀; 堀池麻里子; 姫野 愛; 速水正憲; 五十嵐樹彦; 三浦智行

  第148回日本獣医学会学術集会、2008 年9 月25-27 日、鳥取, 2008, Peer-reviewed

  
• 疎水化ポリγ‐グルタミン酸ナノ粒子を用いるワクチン

  明石満; 赤木隆美; 馬場昌範; 中川晋作; 三浦智行

  日本薬学会年会要旨集, Mar. 2007

  
• Construction and in vivo analysis of R5 single tropic virus that shares the same genetic backbone with dual tropic SHIV-KS661.

  Matsuda K; Ibuki K; Inaba K; Matsuyama M; Hirai K; Yamaguchi-Kabata Y; Hayami M; Miura T

  25th annual Symposium on Nonhuman Primate Models for AIDS, Monterey, U.S.A., Sep. 10-13, 2007, 2007, Peer-reviewed

  
• Studies on CD1d-NKT system conserved among species: Importance of primate models for human disease analysis.

  Saito N; Takahashi M; Shinya E; Akahata W; Shimizu M; Owaki A; Watanabe E; Hidaka C; Kaneko A; Ibuki K; Hayami M; Miura T; Takahashi H

  25th annual Symposium on Nonhuman Primate Models for AIDS, Monterey, U.S.A., Sep. 10-13, 2007, 2007, Peer-reviewed

  
• SIVmac にHIV-1 のプロテアーゼ遺伝子を組み込んだSHIV-pr のin vivo 継代によって生じた遺伝子変異の解析

  石松美沙; 鈴木元; 秋山尚志; 三浦智行; 速水正憲; 井戸栄治

  第21 回日本エイズ学会学術集会・総会、広島、11 月28 日-11 月30 日、2007, 2007, Peer-reviewed

  
• プロテアーゼ、逆転写酵素、およびインテグラーゼの各遺伝子がHIV-1 由来であるSHIV-prti のサルにおけるin vivo 継代

  井戸栄治; 石松美沙; 三浦智行

  第21 回日本エイズ学会学術集会・総会、広島、11 月28 日-11 月30 日、2007, 2007, Peer-reviewed

  
• 抗原固定化生分解腫ナノ粒子ワクチンのサル免疫実験および SHIV 攻撃接種による感染防御能の評価

  姫野愛; 赤木隆美; 伊吹謙太郎; 松山めぐみ; 平井郁; 堀池麻里子; 宇都倫史; 王欣; 馬場昌範; 明石満; 三浦智行

  第55 回日本ウイルス学会学術集会、2007年10月 21日-23 日、札幌, 2007, Peer-reviewed

  
• Dual tropic SHIV-KS661をバックボーンとしたR5 single tropic ウイルスの作成とin vivo 解析

  松田健太; 伊吹謙太郎; 稲葉一寿; 松山めぐみ; 平井郁; 山口由美; 速水正憲; 三浦智行

  第55 回日本ウイルス学会学術集会、2007 年10 月21 日-23 日、札幌, 2007, Peer-reviewed

  
• The effects of low-pathogenic SHIV intrarectal infection on immune cell population of the intestinal tract in comparison to acute-pathogenic SHIV infection

  Kentaro Ibuki; Ariko Miyake; Reii Horiuchi; Naoki Saitou; Hajime Suzuki; Makiko Motohara; Yoshinori Fukazawa; Katsuhisa Inaba; Tomoyuki Miura; Masanori Hayami

  JOURNAL OF MEDICAL PRIMATOLOGY, Aug. 2006

  
• nef 遺伝子欠損サル/ヒト免疫不全キメラウイルス(SHTV)接種による感染防御メカニズ ムの解析

  伊吹謙太郎; 深澤嘉伯; 姫野愛; 稲葉一寿; 齊藤尚紀; 松田健太; 松山めぐみ; 速水正憲; 三浦智行

  第54回日本ウイルス学会学術集会、2006年11月19日-21日、名古屋, 2006, Peer-reviewed

  
• Even low pathogenic SHIV lead to decrease CD4+ T-cell of the small intestine significantly from early phase of infection.

  Fukazawa Y; Miyake A; Ibuki K; Inaba K; Saito N; Motohara M; Horiuchi R; Himeno A; Matsuda K; Nakamura M; Matsuyama M; Hayami M; Miura T

  24th annual Symposium on Nonhuman Primate Models for AIDS, Oct. 4-7, 2006, Atlanta., 2006, Peer-reviewed

  
• CD4reduction and villous atrophy in small intestinal tract are caused by even controlled simian/human immunodeficiency virus infection.

  Inaba K; Fukazawa Y; Horiuch R; Matsuda K; Matsuyama M; Himeno, A; Saito N; Matsuyama M; Ibuki K; Hayami M; Miura T

  24th annual Symposium on Nonhuman Primate Models for AIDS, Oct. 4-7, 2006, Atlanta., 2006, Peer-reviewed

  
• STV/SHTV感受性IL一2 independentア カゲザル細胞株"MT -IL2T" の樹立とその性状解析

  齊藤尚紀; 高橋めぐみ; 清水真澄; 伊吹謙太郎; 速水正憲; 三浦智行; 高橋秀実

  第20 回日本エイ ズ学会学術集会、東京、2006 年11月30- 12月2 日, 2006, Peer-reviewed

  
• Dual tropic SHIV-KS661 をバックボーンとしたR5 single tropic ウイルスとX4 single tropic ウイルスの作製

  松田健太; 松山めぐみ; 伊吹謙太郎; 山口由美; 速水正憲; 三浦智行

  第20 回日本エイズ学会学術集会、2006 年11月30 日-12月2 日、東京, 2006, Peer-reviewed

  
• nef 遺伝子欠損サル/ ヒト免疫不全キメラウイルス(SHTV-NT)免疫ザルに対する急性発症型SHTV攻撃接種早期の全身臓器におけるウイルス動態

  深澤嘉伯; 伊吹謙太郎; 齊藤尚紀; 姫野愛; 稲葉一寿; 松田健太; 松山めぐみ; 元原麻貴子; 速水正憲; 三浦智行

  第20回日本エイズ学会 学術集会、2006年11月30日-12月2日、東京, 2006, Peer-reviewed

  
• プロテアーゼ, 逆転写酵素, およびインチダラー ゼの各遺伝子がfflV-1 由来である新規SHIV のサル感染実験

  井戸栄治; 石松美沙; 速水正憲; 三浦智行

  第20 回日本エイズ学会学術 集会・総会, 東京,11 月30 日-12 月2 日, 2006, 2006, Peer-reviewed

  
• RANTES遺伝子組み込みSHTVによる細胞性免疫応答の増強

  清水佑也; 稲葉一寿; 兼安健太郎; 姫野 愛; 伊吹謙太郎; 三浦智行; 速水正憲; 芳賀 猛

  第54回日本ウイルス学会学術集会、 2006年11月19日-21日、名古屋, 2006, Peer-reviewed

  
• 強毒SHTV感 染サルの全身臓器におけるウイルス変異の解析

  松山めぐみ; 堀内励生; 深澤嘉伯; 稲葉一寿; 伊吹謙太郎; 速水正憲; 三浦智行

  第54回日本ウイルス学会学術集会、2006年11月19日-21日、名古屋, 2006, Peer-reviewed

  
• ウイルス血症が抑制されているSHTV感染アカゲザルでも小腸で は絨毛萎縮とCD4陽性T細胞の減少が認められる

  稲葉一寿; 深澤嘉伯; 堀内励生; 松田健太; 松山めぐみ; 姫野愛; 齊藤尚紀; 中村仁美; 伊吹 謙太郎; 速水正憲; 三浦智行

  第54回日本ウイルス学会学術集会、2006年11月19日-21日、名古屋, 2006, Peer-reviewed

  
• 伝子欠損サル/ ヒト免疫不全キメラウイルスワクチン接種による感染防 御効果の検討一腸管粘膜免疫細胞群の動態解析を主体としてー

  伊吹謙太郎; 深澤嘉伯; 姫野愛; 斉藤尚紀; 元原麻貴子; 稲葉一寿; 松田健太; 松山めぐみ; 速水正憲; 三浦智行

  第142回日本獣医学会学術集会、 2006 年9 月22 日-24 日、山口, 2006, Peer-reviewed

  
• A novel simian immunodeficieny virus from black mangabey (Lophocebus aterrimus) in the Democratic Republic of Congo

  Taichiro Takemura; Michel Ekwalanga; Blaise Bikandou; Eiji Ido; Yumi Yamaguchi-Kabata; Sadayuki Ohkura; Hirotada Harada; Jun Takehisa; Hiroshi Ichimura; Henri-Joseph Parra; Monique Nende; Eric Mubwo; Midingi Sepole; Masanori Hayami; Tomoyuki Miura

  Journal of General Virology, Jul. 2005

  
• A new subtype (subgenotype) Ac (A3) of hepatitis B virus and recombination between genotypes A and E in Cameroon

  Fuat Kurbanov; Yasuhito Tanaka; Kei Fujiwara; Fuminaka Sugauchi; Dora Mbanya; Leopold Zekeng; Nicaise Ndembi; Charlotte Ngansop; Lazare Kaptue; Tomoyuki Miura; Eiji Ido; Masanori Hayami; Hiroshi Ichimura; Masashi Mizokami

  Journal of General Virology, Jul. 2005

  
• DNA vaccination of macaques by full-sized SHIV plasmids that produce non-infectious virus particles

  Horiuchi R; Ido E; Akahata W; Enose Y; Ibuki K; Miura T; Goto T; Takahashi H; Hayami M

  Tenth International Conference on Emerging Infectious Diseases in the Paci 丘c Rim, November 16-17, 2005, Hanoi, Vietnam, 2005, Peer-reviewed

  
• Evolutional conservation of the CD1d molecules among primates.

  Saito N; Takahashi M; Akahata W; Ido E; Hidaka, C; Ibuki, K; Miura T; Hayami M; Takahashi H

  23rd annual Symposium on Nonhuman Primate Models for AIDS, September 21-24,2005, Oregon, 2005, Peer-reviewed

  
• Impaired T cell differentiation in the thymus at the early stages of acute pathogenic SHIV infection in monkeys in comparison to low pathogenic SHIV infection.

  Motohara M; Ibuki K; Miyake A; Fukazawa Y; Inaba K; Suzuki H; Masuda K; Minato N; Kawamoto H; Nakasone T; Honda M; Hayami M; Miura T

  23rd annual Symposium on Nonhuman Primate Models for AIDS, September 21-24, 2005, Oregon, 2005, Peer-reviewed

  
• Generation of a novel SHIV that possesses HIV-1-derived protease gene and its infection to macaque monkeys: a useful tool for in vivo efficacy tests towards HIV protease inhibitors.

  Ishimatsu M; Ido E; Suzuki H; Akiyama H; Miura T; Hayami M

  23rd annual Symposium on Nonhuman Primate Models for AIDS, September 21-24,2005, Oregon, 2005, Peer-reviewed

  
• Construction and "in vitro" properties of chimeric simian and human immunodeficiency viruses having human TNF-alpha and RANTES genes.

  Haga T; Shimizu Y; Okoba M; Goto Y; Miura T; Hayami M

  Keystone Symposium, July 23-28,2005, Sanfrancisco, 2005, Peer-reviewed

  
• Construction and characterization of a new simian/human immunodeficiency chimeric virus(SHIV) having the reverse transcriptase, integrase and the 3' half of HIV-1 genome and its monkey-cell-adapted mutants.

  Akiyama H; Ido E; Miura T; Hayami M

  The XXII Symposium of the International Association for Comparative Research on Leukemia and Related Diseases, July 2-5,2005, Heidelberg, Germany, 2005, Peer-reviewed

  
• サルCD４+T 細胞とCD4+CD8+T 細胞のSIVmac239 に対する感受性の差異

  高橋秀実; 高橋めぐみ; 斉藤尚紀; 守屋慶一; 上坂浩実; 福島達伸; 井戸栄治; 伊吹謙太郎; 三浦 智行; 速水正憲

  第１９回日本エイズ学会、2005 年12 月1 日～3 日、熊本, 2005, Peer-reviewed

  
• 強毒・弱毒SHIV の感染初期における胸腺組織及び胸腺内T 前駆細胞の解析

  元原麻貴子; 伊吹謙太郎; 三宅在子; 深澤嘉伯; 稲葉一寿; 鈴木元; 増田恭子; 河本宏; 仲宗根正; 本多三男; 速水正憲; 三浦智行

  第１９回日本エイズ学会、2005 年12 月1 日～3 日、熊本, 2005, Peer-reviewed

  
• nef 欠損弱毒SHIV のワクチン効果に対するrIFN-γ投与の増強効果

  兼安健太郎; 伊吹謙太郎; 大倉定之; 姫野愛; 喜多正和; 山本俊郎; 佐藤彰彦; 三浦智行; 速水正 憲

  第１９回日本エイズ 学会、2005 年12 月1 日～3 日、熊本, 2005, Peer-reviewed

  
• 強毒、弱毒SHIV 粘膜感染初期の全身臓器におけるウイルス動態の解析

  深澤嘉伯; 三宅在子; 伊吹謙太郎; 鈴木元; 堀内励生; 斉藤尚紀; 元原麻貴子; 稲葉一寿; 姫野愛; 渡邊俊樹; 三浦智行; 速水正憲

  第１９回日本エイズ学会、2005 年12 月1 日～3 日、熊本, 2005, Peer-reviewed

  
• 逆転写酵素とインテグラーゼ遺伝子がHIV-1 由来のSHIV-rti のサル感染実験．

  井戸栄治; 石松美沙; 秋山尚志; 三浦智行; 速水正憲

  第１９回日本エイズ学会、2005 年12 月1 日～3 日、熊本, 2005, Peer-reviewed

  
• SHIV 感染サル検 体を用いたプロウイルスLTR 上のヒストン化学修飾状態の解析

  三宅在子; 石田尚臣; 深澤嘉伯; 伊吹謙太郎; 三浦智行; 速水正憲; 渡邊俊樹

  第２８回日本分子生物学会年 会、2005 年12 月7 日～10 日、福岡, 2005, Peer-reviewed

  
• SHIV 感染サル検 体を用いた感染初期および後期におけるプロウイルスLTR 上のヒストン化学修飾状態の解析

  三宅在子; 石田尚志; 深澤嘉泊; 伊吹謙太郎; 三浦智行; 速水正憲; 渡邊俊樹

  第53 回日本ウイルス学会、2005 年11 月20 日～22 日、横浜, 2005, Peer-reviewed

  
• HIV-1 の逆転写酵素、インテグラーゼ及び３’側遺伝 子をもつSHIV のサル細胞馴化機序の解析

  秋山尚志; 井戸栄治; 三浦智行; 速水正憲

  第53 回日本ウイルス学会、2005 年11 月20 日～ 22 日、横浜, 2005, Peer-reviewed

  
• SIVmac にHIV-1 のプロテアーゼ （PR）遺伝子を組み込んだSHIIV-pr 感染アカゲザルにおけるPR 阻害剤投与実験とその遺伝子 変異解析

  石松美沙; 井戸栄治; 鈴木元; 秋山尚志; 三浦智行; 速水正憲

  第53 回日本ウイルス学会、2005 年11 月20 日～22 日、横浜, 2005, Peer-reviewed

  
• 強毒SHIV の経粘膜・経静脈感染アカゲザルの感染病態および腸病変の比較解 析

  稲葉一寿; 深澤嘉拍; 堀内励生; 三宅在子; 松田健太; 松山めぐみ; 姫野愛; 伊吹謙太郎; 速水正 憲; 三浦智行

  第53 回日本ウイルス学会、2005 年11 月20 日～22 日、横浜, 2005, Peer-reviewed

  
• TNF-α遺伝子挿入 SHIV 感染アカゲサルにおける効果的な免疫応答

  清水祐也; 宮崎恭行; 伊吹謙太郎; 後藤義孝; 三浦智行; 速水正憲; 芳賀猛

  第23 回九州実験動物研究総会、2005 年11 月19 日～20 日、佐賀, 2005, Peer-reviewed

  
• TNF-α遺伝子組み込みSHIV感染ザルに認められた感染早期の効果的な免疫応答

  清水 佑也; 宮崎 恭行; 兼安 健太郎; 鈴木 元; 伊吹 謙太郎; 後藤 義孝; 三浦 智行; 速水 正憲; 芳賀 猛

  日本獣医学会学術集会講演要旨集, Aug. 2004

  
• Anti-AIDS drugs, including AIDS vaccine. Anti-AIDS technique targeted at accessory gene for reactivation of latent HIV-1.

  間陽子; 我妻昭彦; 宮武秀行; 蒲田政和; 緒方一博; 渡来仁; 横田恭子; 三浦智行; 森田裕

  エイズ医薬品等開発研究重点研究総合報告書 平成13-15年度 国際研究グラント事業総合研究報告書, 2004

  
• TNF-α遺伝子組み込みSHIV感染ザルにおける細胞死と免疫応答

  清水 佑也; 宮崎 恭行; 鈴木 元; 伊吹 謙太郎; 三浦 智行; 速水 正憲; 芳賀 猛

  日本エイズ学会誌, Nov. 2003

  
• 成人T細胞白血病ウイルスの系統分析と人類の移動 (特集 日本列島の人類学的多様性)

  三浦 智行

  Science of humanity Bensei, Apr. 2003

  
• 弱毒化Salmonella typhimuriumを用いたDNAワクチンデリバリーシステムの検討

  隈部 志野; 芳賀 猛; 後藤 義孝; 村山 丹穂; 清水 佑也; 松井 英則; 宮田 博規; 三浦 智行

  日本獣医学会学術集会講演要旨集, Mar. 2003

  
• Development of a technique for the inhibition of AIDS symptoms development with the accessory gene involved in the reactivation of latent HIV-1 as target.

  間陽子; 我妻昭彦; 宮武秀行; 緒方一博; 渡来仁; 横田恭子; 三浦智行; 森田裕

  エイズ医薬品等開発研究重点研究報告書 平成14年度, 2003

  
• IL-2遺伝子を導入したSHIVの培養細胞における増殖とIL-2産生能

  鈴木 元; 三浦 智行; 桑田 岳夫; 芳賀 猛; ユーリ・コズレフ; 宇井 雅博; コフィ・テオフィルス; 速水 正憲

  日本獣医学会学術集会講演要旨集, Mar. 2002

  
• Using SHIVs to develop an anti-HIV-1 live-attenuated vaccine

  T Kuwata; T Miura; M Hayami

  TRENDS IN MICROBIOLOGY, Oct. 2001

  
• CCR5タイプHIV-1抑制ケモカインRANTESを発現するSIV/HIVキメラウイルス(SHIV)の作成

  山崎 奈々瀬; 芳賀 猛; 後藤 義孝; 新城 敏晴; 築山 貴実; 桑田 岳夫; 速水 正憲; 三浦 智行

  日本獣医学会学術集会講演要旨集, Mar. 2001

  
• RANTES遺伝子を導入したSHIVの作成と培養細胞における増殖

  芳賀 猛; 山崎 奈々瀬; 桑田 岳夫; 速水 正憲; 三浦 智行

  日本エイズ学会誌, Nov. 2000

  
• IL-6及びTNF-α遺伝子を導入したSHIVの培養細胞における増殖とサイトカイン産生

  芳賀 猛; 桑田 岳夫; 飯田 陶子; 市村 宏; 山崎 奈々瀬; 清水 佑也; 速水 正憲; 三浦 智行

  日本エイズ学会誌, Nov. 1999

  
• Triple HIV-1 infection with group O and group M of different clades in a single Cameroonian AIDS patient

  J Takehisa; L Zekeng; T Miura; E Ido; M Yamashita; Mboudjeka, I; LG Gurtler; M Hayami; L Kaptue

  JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, Jan. 1997

  
• ISOLATION AND PHYLOGENETIC ANALYSIS OF SIMIAN T-CELL LEUKEMIA-VIRUS TYPE-I FROM ORANGUTAN (PONGO-PYGMAEUS)

  K IBUKI; S SETIYANINGSIH; E IDO; T MIURA; M YAMASHITA; A LELANA; D SAJUTHI; M HAYAMI

  JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, Oct. 1995

  
• SEROEPIDEMIOLOGICAL STUDIES ON HTLV-1 IN BRAZIL - GENETIC SEQUENCE OF SEGMENT LTR FROM BRAZILIAN STRAINS ISOLATED FROM 3 DIFFERENT ETHNIC-GROUPS

  R VERONESI; M YAMASHITA; T MIURA; M HAYAMI; D CHAMONE; MG CLIGUET; Y NUKUI; E NEITZERT; R FOCACCIA

  JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, Oct. 1995

  
• PRESENCE OF THE WIDESPREAD SUBTYPE OF HTLV-I IN SOUTH-AFRICA

  M YAMASHITA; J TAKEHISA; T MIURA; E IDO; WB BECKER; BA ROBSON; MLB BECKER; M HAYAMI

  AIDS RESEARCH AND HUMAN RETROVIRUSES, May 1995

  
• PHYLOGENETIC ANALYSIS OP HTLV-I/II FROM COLOMBIA, CHILE AND GHANA

  T MIURA; M YAMASHITA; T IGARASHI; J TAKEHISA; K IBUKI; E IDO; ZANINOVIC, V; L CARTIER; M OSEIKWASI; NK AYSI; K TAJIMA; S SONODA; M HAYAMI

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Apr. 1994

  
• PHYLOGENETIC ANALYSIS OF HTLV-I ISOLATED FROM PERIPHERAL-BLOOD AND SALIVA OF MASHHADI JEWS IN ISRAEL

  M YAMASHITA; T MIURA; J TAKEHISA; E IDO; T IGARASHI; K IBUKI; M HAYAMI; A ACHIRON; B SHOHAT

  AIDS RESEARCH AND HUMAN RETROVIRUSES, Apr. 1994

  
• PHYLOGENETIC SUBTYPES OF HUMAN T-LYMPHOTROPIC VIRUS TYPE-I AND THEIR RELATIONS TO THE ANTHROPOLOGICAL BACKGROUND

  T MIURA; T FUKUNAGA; T IGARASHI; M YAMASHITA; E IDO; S FUNAHASHI; T ISHIDA; K WASHIO; S UEDA; K HASHIMOTO; M YOSHIDA; M OSAME; B SENSINGHAL; ZANINOVIC, V; L CARTIER; S SONODA; K TAJIMA; Y INA; T GOJOBORI; M HAYAMI

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 1994, Peer-reviewed

  
• Survey of simian immunodeficiency virus among nonhuman primate populations

  M. Hayami; E. Ido; T. Miura

  Current Topics in Microbiology and Immunology, 1994

  
• 「ヒトレトロウイルス」

  三浦智行; 速水正憲

  日本生化学会編『分子進化実験法』 新生化学実験講座16 、東京化学同人、 \n39- 53頁, 1993, Peer-reviewed

  
• エイズ関連ウイルスの分子系統解析 (感染症ウイルスの進化<特集>)

  三浦 智行; 速水 正憲

  遺伝, Oct. 1992

  
• EVOLUTIONARY ORIGIN OF HUMAN AND SIMIAN IMMUNODEFICIENCY VIRUSES

  T GOJOBORI; EN MORIYAMA; Y INA; K IKEO; T MIURA; H TSUJIMOTO; M HAYAMI; S YOKOYAMA

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jun. 1990, Peer-reviewed

  
• AIDSウイルスの起源を考える-HIV関連ウイルスの相互関係

  三浦智行

  メディカルトリビューン,21,44-45, 1988

  

Books and Other Publications

• 「成人T 細胞白血病ウイルスの系統分析と人類の移動」

  三浦智行, Contributor

  Science of Humanity ,42:50-59 頁, 2003, Not refereed

  
• Surveys of SIV among nonhuman primate populations.

  Hayami, M

  Current Topics in Microbiology and Immunology, Springer-Verlag,188/,1-20, 1994, Not refereed

  
• ヒトレトロウイルス

  三浦智行

  日本生化学会編,新生化学実験講座第16巻分子進化実験法,39-53, 1992, Not refereed

  

Industrial Property Rights

• 特開2008-001598, 特願2004-298188, アポトーシス誘導物質を含む医薬組成物

  間 陽子; 渡来 仁; 三浦 智行

  

External funds: Kakenhi

• Study of virus reservoir injury treatment on primate AIDS model

  Grant-in-Aid for Scientific Research (B)

  Basic Section 42040:Laboratory animal science-related

  Kyoto University

  Tomoyuki Miura

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  多剤併用療法;機能的治癒;動物モデル;感染症;アカゲザル;HIV;SHIV;エイズ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03146/
• Evaluation of protective immune responses by recombinant BCG/vaccinia prime-boost AIDS vaccine in macaque model of SIV infection

  Grant-in-Aid for Scientific Research (C)

  Basic Section 42040:Laboratory animal science-related

  Japan BCG Laboratory

  Kazuhiro Matsuo

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  エイズワクチン;細胞傷害性T細胞;サル免疫不全ウイルス;BCG;ワクシニアウイルス;インド産アカゲザル;組換えBCG;組換えワクシニアウイルス;キラーT細胞;細胞性免疫;CTL;PEST配列;抗原提示能;SIV感染モデル;霊長類モデル;組換えワクシニア

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K06049/
• Development of a mice having simian immune systems-Establishment of a new animal model for analysis of pathogenesis in viral infection

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Kentaro Ibuki

  From 01 Apr. 2016, To 31 Mar. 2018, Project Closed

  小動物モデル;ウイルス感染症;免疫不全ウイルス;サル造血幹細胞;免疫不全マウス;実験動物モデル;サル骨髄造血幹細胞移植;疾患モデル;NOGマウス;ウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K14593/
• Empirical study on the formation of AIDS pathogenesis by primate model

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Tomoyuki MIURA

  From 01 Apr. 2016, To 31 Mar. 2019, Project Closed

  HIV;SHIV;アカゲザル;動物モデル;感染症;エイズ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H04682/
• HIV-1感染症の機能的治癒におけるウイルスリザーバーサイズの意義

  Grant-in-Aid for Scientific Research (B)

  Tottori University;Kyoto University

  五十嵐 樹彦

  From 01 Apr. 2014, To 31 Mar. 2017, Declined

  エイズ;抗ウイルス剤;多剤併用療法;SIV;リザーバー;リンパ球;リバウンド

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26290032/
• Establishment of a simple, easy and useful new recombinant virus manufacture system using a homologous recombination phenomenon

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Tomoyuki MIURA

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  感染症;組換えウイルス;エイズ;SHIV;HIV-1mt;デングウイルス;ダニ媒介性脳炎ウイルス;相同組換え;ウイルス;動物モデル;微生物

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23658240/
• Basic study on viral genome related to pathogenesis of SHIV infection in non-human primate AIDS model

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Tomoyuki MIURA

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  感染症;エイズ;動物モデル;アカゲザル;HIV;SHIV;病原性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21300152/
• Elucidation of the mechanism that HIV got over a species barrier from monkey to human using simian/human recombinant immunodeficiency virus

  Grant-in-Aid for Scientific Research (B)

  Heian Jogakuin(St.Agnes')University;Kyoto University

  Masanori HAYAMI

  From 01 Apr. 2006, To 31 Mar. 2009, Project Closed

  感染症;ウイルス;エイズ;アカゲザル;実験動物;遺伝子組み換え;微生物;サル;組み換え;獣医学;病理学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18380182/
• Study for molecular basis of AIDS pathogenesis on non-human primate model

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Tomoyuki MIURA

  From 01 Apr. 2006, To 31 Mar. 2009, Project Closed

  感染症;ウイルス;エイズ;アカゲザル;病原性;病理学;微生物;獣医学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18300142/
• Molecular epidemiology of HIV in central Africa - Searching for the origin of AIDS virus and its future

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Eiji IDO

  From 01 Apr. 2005, To 31 Mar. 2009, Project Closed

  ウイルス;進化;エイズ;HIV;分子疫学;HIV-1;SIV;遺伝子解析;中央アフリカ;レトロウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17256004/
• Comparison between histopathological changes and infectious virus productive organs of acute pathogenic and non-pathogenic SHIV infected monkeys-The detection of HIV-1 productive organs.

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Kentaro IBUKI

  From 01 Apr. 2001, To 31 Mar. 2005, Project Closed

  SHIV;病原性;感染初期;粘膜感染;体内増殖部位;腸管免疫;粘膜免疫;γδT細胞;NK活性;サル個体レベルの病態;AIDS発症・非発症;病理組織学的解析, SHIV;pathogenicity;acute phase;mucosal infection;tissue distribution of virus producing cells

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13308049/
• 遺伝子改変SHIVを用いたHIV-1の病原性と宿主免疫応答の解析

  Grant-in-Aid for Scientific Research on Priority Areas (A)

  Biological Sciences

  Kyoto University

  三浦 智行

  From 01 Apr. 2001, To 31 Mar. 2002, Project Closed

  エイズ;動物モデル;HIV;SIV;サイトカイン;病原性;アカゲザル;免疫応答

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13015210/
• Origin and molecular evolution of primate lentiviruses-Genetic analysis of HIV/HTLV in Africa

  Grant-in-Aid for Scientific Research (A).

  KYOTO UNIVERSITY

  Masanori HAYAMI

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  AIDS;HIV-1;霊長類レンチウィルス;SIV;マンドリル;中央アフリカ;カメルーン;霊長類レンチウイルス;ドリル, AIDS;HIV-1;primate lentivirus;SIV;Mandrill;central Africa;Cameroon

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10041195/
• Isolation and analyzes of HIV・HTLV related viruses from humans and monkeys in Africa

  Grant-in-Aid for international Scientific Research

  KYOTO UNIVERSITY

  Masanori HAYAMI

  From 01 Apr. 1996, To 31 Mar. 1998, Project Closed

  エイズ;アフリカ;HIV;SIV;HTLV;カメルーン;コンゴ;分子疫学;中央アフリカ;重感染;リコンビネーション;ピグミー;チンパンジー, AIDS;Africa;HIV;SIV;HTLV;Cameroon;Congo;molecular epidemiology

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08041173/
• アル白血病ウイルスの遺伝子と病態

  Grant-in-Aid for Encouragement of Young Scientists (A)

  Kyoto University

  三浦 智行

  From 01 Apr. 1995, To 31 Mar. 1996, Project Closed

  白血病;レトロウイルス;遺伝子解析;動物モデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07760300/
• 霊長類レトロウイルスの分子進化

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  三浦 智行

  From 01 Apr. 1995, To 31 Mar. 1996, Project Closed

  分子進化;レトロウイルス;エイズ;白血病;HIV;HTLV

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07265211/
• Pathology and Molecular Evolution of HTLV in Asia

  Grant-in-Aid for international Scientific Research

  Kagoshima University

  Mitsuhiro OSAME

  From 01 Apr. 1995, To 31 Mar. 1998, Project Closed

  HTLV;成人T細胞白血病;分子疫学;系統解析;STLV;HAM;TSP;HTLV-I;STLV-I;少数民族;分子系統解析;ヒト細胞白血病;HTLV-1;STLV-1;オランウータン;ピグミー, HTLV;ATL;molecular epidemiology;phylogenetic analysis;STLV;HAM;TSP

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07042008/
• サル白血病ウイルスの遺伝子と病態

  Grant-in-Aid for Encouragement of Young Scientists (A)

  Kyoto University

  三浦 智行

  From 01 Apr. 1994, To 31 Mar. 1995, Project Closed

  白血病;レトロウイルス;遺伝子解析;動物モデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06760280/
• 霊長類レトロウイルスの分子進化

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  三浦 智行

  From 01 Apr. 1994, To 31 Mar. 1997, Project Closed

  分子進化;レトロウイルス;エイズ;白血病;HIV;HTLV

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06273216/
• Epidemiology and pathology of human retrovirus infection

  Grant-in-Aid for international Scientific Research

  Kagoshima University

  Mitsuhiro OSAME

  From 01 Apr. 1994, To 31 Mar. 1995, Project Closed

  成人T細胞白血病;HAM;HTLV-1, Adult T-cell Leukemia;HAM;HTLV-1

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06042013/
• Viroepidemiological study of HTLV-I/II in Jamaica and Colombia

  Grant-in-Aid for international Scientific Research

  Kagoshima University

  Shunro SONODA

  From 01 Apr. 1994, To 31 Mar. 1995, Project Closed

  HTLV-I;II;ATL;HAM;TSP;Infective dermatitis;日本人患者;黒人患者;南米インデイオ患者, HTLV-I;II;ATL;HAM;TSP;Infective dermatitis;Japanese;Blacks;Andean natives

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06042011/
• Isolation of AIDS-related viruses from African Primates

  Grant-in-Aid for international Scientific Research

  KYOTO UNIVERSITY

  Masanori HAYAMI

  From 01 Apr. 1993, To 31 Mar. 1996, Project Closed

  エイズ;アフリカ;HIV;カメルーン;重感染;リコンビネーション;SIV;分子疫学;ガーナ;ケニア;ガボン;レトロウイルス, AIDS;Africa;HIV;Cameroon;Double infection;recombination

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05041111/
• Epidemiology and pathology of human retro virus infection.

  Grant-in-Aid for international Scientific Research

  Kagoshima Universitiy

  Mitsuhiro OSAME

  From 01 Apr. 1992, To 31 Mar. 1994, Project Closed

  ATL;HTLV-I;HTLV-II;HAM;TSP;STLV;HIV-I;HIV-II;SIV;HIV;STLV-I

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04042017/
• Viroepidemiological study on HTLV-I/II in Jamaica and Colombia

  Grant-in-Aid for international Scientific Research

  Kagoshima University

  Shunro SONODA

  From 01 Apr. 1992, To 31 Mar. 1994, Project Closed

  HTLV-I;II;ATL;HAM;TSP;HLA;遺伝疫学, HTLV-I;II;ATL;HAM;TSP;HLA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04042016/
• PCR法を用いた新しいエイズ関連ウイルスの検出とその系統発生学的研究

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  三浦 智行

  From 01 Apr. 1991, To 31 Mar. 1992, Project Closed

  ヒト免疫不全ウイルス;サル免疫不全ウイルス;エイズ;PCR;HIV;SIV;分子進化;系統樹

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03219208/
• 感染症DNAク-ロンを用いたHIU/SIUの病原性と変異の解析

  Grant-in-Aid for Cancer Research

  Kyoto University

  速水 正憲

  From 01 Apr. 1991, To 31 Mar. 1992, Project Closed

  サル免疫不全ウイルス;エイズ;ヒト免疫不全ウイルス;組換えウイルス;サル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03152062/
• Seroepidemiology of ATL/AIDS-related viruses and comparative virology and pathology

  Grant-in-Aid for international Scientific Research

  Kyoto University

  Masanori HAYAMI

  From 01 Apr. 1991, To 31 Mar. 1992, Project Closed

  ATL;エイズ;HTLVー1;HAM;TSP;HIV;SIV;STLVー1;ヒト免疫不全ウイルス;サル免疫不全ウイルス, ATL;AIDS;HTLV-1;HAM;TSP;HIV;SIV;STLV-1

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02042004/
• PCR法を用いた新しいエイズ関連ウイルスの検出とその系統発生学的研究

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  三浦 智行

  From 01 Apr. 1990, To 31 Mar. 1991, Project Closed

  ヒト免疫不全ウイルス;サル免疫不全ウイルス;エイズ;PCR;HIV;SIV;分子進化;系統樹

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02235208/
• 感染性DNAクロ-ンを用いたHIV/SIVの病原性と変異の解析

  Grant-in-Aid for Cancer Research

  Kyoto University

  速水 正憲

  From 01 Apr. 1990, To 31 Mar. 1991, Project Closed

  サル免疫不全ウイルス;SIV;サル;ヒト免疫不全ウイルス;HIV;組換えウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02152049/
• HIVのR遺伝子(vpr)の同定とその機能解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Kyoto University

  三浦 智行

  From 01 Apr. 1989, To 31 Mar. 1990, Project Closed

  ヒト免疫ウイルス;サル免疫不全ウイルス;HIV;SIV;vpr 遺伝子;感染性クロ-ン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01653503/
• 感染性DNAクローンを用いたHIV/SIVの病原性と変異の解析

  Grant-in-Aid for Cancer Research

  Kyoto University

  速水 正憲

  From 01 Apr. 1989, To 31 Mar. 1990, Project Closed

  ヒト免疫不全ウイルス;サル免疫不全ウイルス;感染性DNAクローン;アフリカミドリザル;マンドリル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01015040/

External funds: others

• Study on small molecule for anti-HIV-1 Vpr and its application for molecular imaging

  保健医療分野における基礎研究推進事業

  From 01 Apr. 2006, To 31 Mar. 2010

  間陽子
• Immunological fundamental researches about prevention of HIV infection and AIDS onset

  厚生労働省エイズ対策研究事業

  From 01 Apr. 2009, To 31 Mar. 2012

  森一泰
• The elucidation of the AIDS pathogenesis formation basis in the intestinal tract and application to treatment using the primate model

  厚生労働省政策創薬総合研究推進事業エイズ医薬品等開発研究国際研究グラント

  From 01 Apr. 2006, To 31 Mar. 2009

  三浦智行
• Study on prevention of HIV infection

  厚生労働省エイズ対策研究事業

  From 01 Apr. 2006, To 31 Mar. 2009

  山本直樹
• Development of the antiretroviral vaccine which applied nanoparticles

  文部科学省戦略的創造研究推進事業

  From 01 Apr. 2006, To 31 Mar. 2008

  明石満
• Use of vaccinia vector as the HIV vaccine

  独立行政法人科学技術振興機構

  From 01 Jan. 2013, To 31 Dec. 2013

  志田壽利
• Induction of anti-AIDS immunity in monkeys (2014)

  国立大学法人北海道大学

  From 01 Apr. 2014, To 31 Mar. 2015

  志田壽利
• Induction of anti-AIDS immunity in monkeys (2015)

  国立大学法人北海道大学

  From 01 Apr. 2015, To 31 Mar. 2016

  志田壽利
• Study on development of HIV infection protective vaccine (study on monkey SHIV infection model, study on degradation and presentation of HIV antigen) (2015)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2015, To 31 Mar. 2016

  俣野哲朗
• Empirical research on HIV/AIDS for elucidating the relationship between infection dynamics and pathological conditions (Rhesus monkey experiment, establishment of HIV-1rmt) (2015)

  国立大学法人徳島大学

  From 01 Apr. 2015, To 31 Mar. 2016

  足立昭夫
• Development of new therapeutic method aiming at "functional cure" of HIV infection using neutralizing antibody (POC test of new therapeutic method using primates) (2015)

  国立大学法人熊本大学

  From 01 Apr. 2015, To 31 Mar. 2016

  松下修三
• Study on measures against animal-derived infectious diseases (virological analysis of SRV that causes Japanese monkey thrombocytopenia) (2015)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2015, To 31 Mar. 2016

  森川茂
• Research on HIV protective vaccine development (2016)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2016, To 31 Mar. 2017

  俣野哲朗
• Empirical research on HIV/AIDS for elucidating the relationship between infection dynamics and pathological conditions (Rhesus monkey experiment, establishment of HIV-1rmt) (2016)

  国立大学法人徳島大学

  From 01 Apr. 2016, To 31 Mar. 2017

  足立昭夫
• Development of new therapeutic method aiming at "functional cure" of HIV infection using neutralizing antibody (POC test of new therapeutic method using primates) (2016)

  国立大学法人熊本大学

  From 01 Apr. 2016, To 31 Mar. 2017

  松下修三
• Evaluation of BCG/m8Δ vaccinia combined anti-AIDS vaccine effect (2016)

  日本ビーシージー製造株式会社　代表取締役社長

  From 01 Apr. 2016, To 31 Mar. 2017

  松尾和浩
• Empirical research on HIV/AIDS for elucidating the relationship between infection dynamics and pathological conditions (Rhesus monkey experiment, establishment of HIV-1rmt) (2017)

  国立大学法人徳島大学

  From 01 Apr. 2017, To 31 Mar. 2018

  足立昭夫
• Development of new therapeutic method aiming at "functional cure" of HIV infection using neutralizing antibody (POC test of new therapeutic method using primates) (2017)

  国立大学法人熊本大学

  From 01 Apr. 2017, To 31 Mar. 2018

  松下修三
• Research on HIV protective vaccine development (2017)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2017, To 31 Mar. 2018

  俣野哲朗
• Development of new therapeutic method aiming at "functional cure" of HIV infection using neutralizing antibody (POC test of new therapeutic method using primates) (2018)

  国立大学法人熊本大学

  From 01 Apr. 2018, To 31 Mar. 2019

  松下修三
• Research on elucidation and improvement of immune pathology for the cure of HIV infection (2018)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2018, To 31 Mar. 2019

  立川愛
• Study on development of functional antibody-induced HIV vaccine (2018)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2018, To 31 Mar. 2019

  俣野哲朗
• Evaluation of BCG/m8Δ vaccinia combined anti-AIDS vaccine effect (2018)

  日本ビーシージー製造株式会社

  From 01 Apr. 2018, To 31 Mar. 2019

  松尾和浩
• Research and development aiming at cure of HIV infection by neutralizing antibody (in vivo effect of CD4mc using non-human primate (NHP) model) (2019)

  国立大学法人熊本大学

  From 01 Apr. 2019, To 31 Mar. 2020

  松下修三
• Research on elucidation and improvement of immune pathology for cure of HIV infection (Study on T cell transplantation in monkey AIDS model) (2019)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2019, To 31 Mar. 2020

  立川愛
• Study on development of functional antibody-induced HIV vaccine (Study on HIV-infected monkey model for evaluation of antibody-induced vaccine) (2019)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2019, To 31 Mar. 2020

  俣野哲朗
• Research and development aiming at cure of HIV infection by neutralizing antibody (in vivo effect of CD4mc using non-human primate (NHP) model) (2020)

  国立大学法人熊本大学

  From 01 Apr. 2020, To 31 Mar. 2021

  松下修三
• Research on elucidation and improvement of immune pathology for cure of HIV infection (Study on T cell transplantation in monkey AIDS model) (2020)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2020, To 31 Mar. 2021

  立川愛
• Study on development of functional antibody-induced HIV vaccine (Study on HIV-infected monkey model for evaluation of antibody-induced vaccine) (2020)

  国立研究開発法人日本医療研究開発機構

  From 01 Apr. 2020, To 31 Mar. 2021

  俣野哲朗
• Study on effect of green tea on new coronavirus

  京都茶業研究所

  From 28 May 2020, To 31 Mar. 2021

  神田真帆

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Human and Environmental Studies II

  KK23, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Human and Environmental Studies I

  KK22, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Virus Diversity

  JJ09, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Studies on interdisciplinary environment II

  3002, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Studies on interdisciplinary environment I

  3001, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Studies on Interdisciplinary environment II

  Q002, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Studies on Interdisciplinary environment I

  Q001, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Virus Diversity 2

  JJ15, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar in Dynamics of Natural Environment

  Q019, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Exercise in Dynamics of Biological Environment 2

  Q010, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Exercise in Dynamics of Biological Environment 1

  Q009, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Virus Diversity 1

  JJ14, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Research in Human and Environmental Studies I

  RR03, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Seminar in Human and Environmental Studies 2

  RR06, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Seminar in Human and Environmental Studies 1

  RR05, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Research in Human and Environmental Studies II

  RR04, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar in Human and Environmental Studies

  RR07, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Research in Human and Environmental Studies II

  RR04, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Research in Human and Environmental Studies I

  RR03, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar in Dynamics of Natural Environment

  Q019, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar in Human and Environmental Studies

  RR07, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Seminar in Human and Environmental Studies 2

  RR06, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Seminar in Human and Environmental Studies 1

  RR05, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Studies on Interdisciplinary environment I

  Q001, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Virus Diversity 2

  JJ15, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Virus Diversity 1

  JJ14, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Exercise in Dynamics of Biological Environment 2

  Q010, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Exercise in Dynamics of Biological Environment 1

  Q009, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Studies on Interdisciplinary environment II

  Q002, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Studies on interdisciplinary environment I

  3001, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Human and Environmental Studies I

  KK22, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Virus Diversity

  JJ09, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Studies on interdisciplinary environment II

  3002, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Human and Environmental Studies II

  KK23, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Studies on Interdisciplinary environment I

  Q001, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Virus Diversity 1

  M062, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Virus diversity

  M080, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Studies on interdisciplinary environment I

  3001, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Studies on interdisciplinary environment II

  3002, Year-long, Graduate School of Human and Environmental Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Studies on Interdisciplinary environment II

  Q002, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Seminar in Dynamics of Natural Environment

  Q019, Year-long, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Exercise in Dynamics of Biological Environment 2

  Q010, Fall, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Exercise in Dynamics of Biological Environment 1

  Q009, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Virus Diversity 2

  M063, Fall, Graduate School of Human and Environmental Studies, 2
• From Apr. 2011, To Mar. 2012

  微生物学

  Year-long, 医学部
• From Apr. 2011, To Mar. 2012

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2012, To Mar. 2013

  Microbiology

  Year-long, 医学部
• From Apr. 2012, To Mar. 2013

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2013, To Mar. 2014

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2013, To Mar. 2014

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2013, To Mar. 2014

  Virus Diversity 2

  Year-long, 人間・環境学研究科
• From Apr. 2013, To Mar. 2014

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2013, To Mar. 2014

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2013, To Mar. 2014

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2014, To Mar. 2015

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Virus Diversity 1

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2014, To Mar. 2015

  The Front Line of Life Science Research I

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Virus diversity

  Year-long, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2015, To Mar. 2016

  Virus and Life Science

  Fall, 全学共通科目
• From Apr. 2015, To Mar. 2016

  The Front Line of Life Science Research I

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2015, To Mar. 2016

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Virus diversity

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2016, To Mar. 2017

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2016, To Mar. 2017

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Virus diversity

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2017, To Mar. 2018

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2017, To Mar. 2018

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  ILAS Seminar

  Spring, 全学共通科目
• From Apr. 2018, To Mar. 2019

  Virus diversity

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Virus diversity

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2019, To Mar. 2020

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Virus Diversity

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2020, To Mar. 2021

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Virus Diversity

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Virus Diversity 1

  Spring, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Virus Diversity 2

  Fall, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Special Exercise in Dynamics of Biological Environment 1

  Spring, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Special Exercise in Dynamics of Biological Environment 2

  Fall, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Special Studies on Interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Special Studies on Interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Studies on interdisciplinary environment II

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Studies on interdisciplinary environment I

  Year-long, 人間・環境学研究科
• From Apr. 2021, To Mar. 2022

  Special Seminar in Dynamics of Natural Environment

  Year-long, 人間・環境学研究科

Participation in PhD Defense

• The Study on Neutralization of Human Immunodeficiency Virus and SARS CoV-2 - Neutralization Resistance of SHIV and Neutralization Assay for SARS CoV-2 -

  PISIL YALCIN, Graduate School of Human and Environmental Studies, Chief Examiner

  24 May 2021

Part-time lecturer

• From 01 Apr. 2024, To 31 Mar. 2025

  動物病理学

  学校法人　南京都学園
• From 01 Apr. 2019, To 31 Mar. 2020

  動物感染症学１

  学校法人南京都学園
• From 01 Apr. 2019, To 31 Mar. 2020

  動物疾病看護学２

  学校法人南京都学園
• From 01 Apr. 2019, To 31 Mar. 2020

  動物病理学

  学校法人南京都学園
• From 01 Apr. 2019, To 31 Mar. 2020

  動物感染症学

  学校法人南京都学園
• From 01 Apr. 2020, To 31 Mar. 2021

  動物感染症学１

  学校法人南京都学園
• From 01 Apr. 2020, To 31 Mar. 2021

  動物疾病看護学２

  学校法人南京都学園
• From 01 Apr. 2020, To 31 Mar. 2021

  動物病理学

  学校法人　南京都学園
• From 01 Apr. 2020, To 31 Mar. 2021

  動物感染症学

  学校法人　南京都学園
• From 01 Apr. 2021, To 31 Mar. 2021

  学校法人南京都学園
• From 01 Apr. 2023, To 31 Mar. 2024

  動物感染症学Ⅰ

  学校法人　南京都学園
• From 01 Apr. 2023, To 31 Mar. 2024

  動物感染症学Ⅱ

  学校法人　南京都学園
• From 01 Apr. 2023, To 31 Mar. 2024

  動物病理学

  学校法人　南京都学園