Basic Information

Faculty

• 薬学部

Professional Memberships

• American Chemical Society
• 日本プロセス化学会
• ヨウ素学会
• 日本ペプチド学会
• 日本化学会
• 有機合成化学協会
• 日本薬学会

Academic Degree

• 修士（薬科学）(京都大学)
• 博士（薬科学）(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院薬学研究科修士課程薬科学専攻, 修了
• 京都大学, 大学院薬学研究科博士後期課程薬科学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 薬学部薬科学科, 卒業

High School

• High School

  滋賀県立膳所高等学校

Research History

• From Nov. 2024, To Present

  Kyoto University, Graduate School of Pharmaceutical Sciences, 講師
• From Nov. 2019, To Oct. 2024

  Kyoto University, Graduate School of Pharmaceutical Sciences, Assistant Professor
• From Apr. 2018, To Oct. 2019

  Kyoto University, Graduate School of Pharmaceutical Sciences, Assistant Professor
• From Apr. 2017, To Mar. 2018

  Kyoto University, Graduate School of Pharmaceutical Sciences, Research Fellow
• From Apr. 2015, To Mar. 2017

  University of Illinois at Urbana-Champaign, Research Fellow
• From Apr. 2012, To Mar. 2015

  Japan Society for the Promotion of Science, Research Fellow

Language of Instruction

• Japanese
• English

ID,URL

• ORCID ID

  0000-0002-5679-6701

• J-Global ID

  201801001423568407

• Researcher ID

  E-1117-2019

• External link

  http://orgchem.pharm.kyoto-u.ac.jp/staff/nanjo/

Website(s) (URL(s))

• http://orgchem.pharm.kyoto-u.ac.jp/staff/nanjo/

researchmap URL

• https://researchmap.jp/7000023221

Research

Research Topics, Overview of the research

• Research Topics

  1.Development of synthetic methods for peptides; 2. Development of organocatalysis enabling both high reactivity and selectivity.

• Overview of the research

  Synthetic methods which enable the rapid and precise construction of complex organic molecules are highly demanded. I am developing new synthetic approach toward specialty peptides, the attracting drug discovery seeds. And the development of new molecular catalysts achieving both high activity and selectivity is also ongoing.

Research Interests

• Synthetic Organic Chemistry

Research Areas

• Life sciences, Pharmaceuticals - chemistry and drug development

Papers

• Oxidative Functionalization of Peptide Side Chains Enabled by N-Chlorination of Amides

  Takeshi Nanjo; Ayaka Matsumoto; Takuma Oshita; Yoshiji Takemoto

  MEDCHEM NEWS, May 2024, Invited, Lead author, Corresponding author

  
• Bulky Alkyl Substituents Enhance the Photocatalytic Activity of Pyridine-Based Donor–Acceptor Molecules in the Direct Reductive Cleavage of the C–Br Bond of Aliphatic Bromides

  Natsuki Kato; Yuta Seki; Takeshi Nanjo; Yoshiji Takemoto

  Organic Letters, 19 Jul. 2024, Peer-reviewed, Invited, Corresponding author

  
• A Benzophenothiazine/Boronic Acid Hybrid Photocatalyst Enables the Single Electron Transfer (SET) to Carboxy Groups: SET-Initiated Cyclization of α,β-Unsaturated Carboxylic Acids

  Taichi Yumura; Takeshi Nanjo; Yoshiji Takemoto

  ACS Catalysis, 18 Sep. 2023, Peer-reviewed

  
• Electron Donor–Acceptor (EDA) Complex between a Triarylamine and B(C₆F₅)₃ for the Photocatalytic Dehydrogenative Cross-Coupling of Phenols

  Natsuki Kato; Takeshi Nanjo; Yoshiji Takemoto

  Chemical and Pharmaceutical Bulletin, 01 Sep. 2023, Peer-reviewed, Corresponding author

  
• Synthesis of Chlorinated Oligopeptides via γ- and δ-Selective Hydrogen Atom Transfer Enabled by the N-Chloropeptide Strategy

  Takeshi Nanjo; Ayaka Matsumoto; Takuma Oshita; Yoshiji Takemoto

  Journal of the American Chemical Society, 18 Aug. 2023, Peer-reviewed, Lead author, Corresponding author

  
• Rhodium‐Catalyzed C−H Alkylation for the Stereoselective Synthesis of β,β‐Disubstituted Dehydroamino‐Acid Motifs

  Takeshi Nanjo; Hikari Sada; Taisei Nagaya; Yuri Maruo; Yoshiji Takemoto

  Asian Journal of Organic Chemistry, 12 Jun. 2023, Peer-reviewed, Invited, Lead author, Corresponding author

  
• Mechanistic Insight into the TBHP-Mediated Decarboxylative Condensation of α-Ketoacids: Reaction Development and Application to Oligopeptide Synthesis

  Kosuke Yoshikawa; Natsuki Kato; Takeshi Nanjo; Yoshiji Takemoto

  Chemical and Pharmaceutical Bulletin, 01 May 2023, Peer-reviewed, Corresponding author

  
• ChemInform Abstract: Synthesis of 3-Acyl-2-arylindole via Palladium-Catalyzed Isocyanide Insertion and Oxypalladation of Alkyne.

  Takeshi Nanjo; Sho Yamamoto; Chihiro Tsukano; Toshiji Takemoto

  ChemInform, Nov. 2013, Peer-reviewed

  
• A Pyridine-Based Donor–Acceptor Molecule: A Highly Reactive Organophotocatalyst That Enables the Reductive Cleavage of C–Br Bonds through Halogen Bonding

  Natsuki Kato; Takeshi Nanjo; Yoshiji Takemoto

  ACS Catalysis, 01 Jul. 2022, Peer-reviewed, Corresponding author

  
• Boronic Acid-Mediated Photocatalysis Enables the Intramolecular Hydroacylation of Olefins Using Carboxylic Acids

  Taichi Yumura; Takeshi Nanjo; Yoshiji Takemoto

  EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Jul. 2022, Peer-reviewed, Invited

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• Late-Stage Installation of Dehydroamino Acid Motifs into Peptides Enabled by an N-Chloropeptide Strategy

  Takeshi Nanjo; Takuma Oshita; Ayaka Matsumoto; Yoshiji Takemoto

  Chemistry - A European Journal, 27 Jun. 2022, Peer-reviewed, Lead author, Corresponding author

  
• Total Synthesis of Lyconesidine B: Approach to a Three-Dimensional Tetracyclic Skeleton of Amine-Type Fawcettimine Core and Studies of Asymmetric Synthesis

  Tomohiro Kurose; Moeko Itoga; Takeshi Nanjo; Yoshiji Takemoto; Chihiro Tsukano

  Bulletin of the Chemical Society of Japan, 15 Jun. 2022, Peer-reviewed

  
• Highly Stereoselective, Organocatalytic Mannich-type Addition of Glyoxylate Cyanohydrin: A Versatile Building Block for the Asymmetric Synthesis of β-Amino-α-ketoacids

  Yusuke Tokuhiro; Kosuke Yoshikawa; Sei Murayama; Takeshi Nanjo; Yoshiji Takemoto

  ACS Catalysis, 06 May 2022, Peer-reviewed, Corresponding author

  
• Photocatalytic C–O Bond Cleavage of Alcohols Using Xanthate Salts

  Takeshi Nanjo; Tatsuki Matsugasako; Yuri Maruo; Yoshiji Takemoto

  Organic Letters, 14 Jan. 2022, Peer-reviewed, Lead author, Corresponding author

  
• Photocatalytic Activation of Elemental Sulfur Enables a Chemoselective Three-Component Thioesterification

  Sho Murakami; Takeshi Nanjo; Yoshiji Takemoto

  ORGANIC LETTERS, Oct. 2021, Peer-reviewed

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• Total Synthesis of Lyconesidine B, a Lycopodium Alkaloid with an Oxygenated, Amine-Type Fawcettimine Core

  Tomohiro Kurose; Chihiro Tsukano; Takeshi Nanjo; Yoshiji Takemoto

  ORGANIC LETTERS, Feb. 2021, Peer-reviewed

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• Mild and Chemoselective Thioacylation of Amines Enabled by the Nucleophilic Activation of Elemental Sulfur

  Masato Saito; Sho Murakami; Takeshi Nanjo; Yusuke Kobayashi; Yoshiji Takemoto

  Journal of the American Chemical Society, 06 May 2020, Peer-reviewed

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• A Hydroperoxide-Mediated Decarboxylation of α-Ketoacids Enables the Chemoselective Acylation of Amines

  Takeshi Nanjo; Natsuki Kato; Xuan Zhang; Yoshiji Takemoto

  Chemistry - A European Journal, 05 Dec. 2019, Peer-reviewed, Lead author

  
• Divergent and Scalable Synthesis of α-Hydroxy/Keto-β-amino Acid Analogues by the Catalytic Enantioselective Addition of Glyoxylate Cyanohydrin to Imines

  Takeshi Nanjo; Xuan Zhang; Yusuke Tokuhiro; Yoshiji Takemoto

  ACS Catalysis, 02 Oct. 2019, Peer-reviewed, Lead author

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• Chemoselective methylene oxidation in aromatic molecules

  Jinpeng Zhao; Takeshi Nanjo; Emilio C. de Lucca; M. Christina White

  Nature Chemistry, 17 Dec. 2018, Peer-reviewed

  
• Synthesis of (Z)-Alkenes by Catalytic Photoisomerization

  Takeshi Nanjo

  Journal of Synthetic Organic Chemistry, Japan, 01 Dec. 2018, Invited, Lead author, Corresponding author

  
• Oxidative Decarboxylation Enables Chemoselective, Racemization-Free Esterification: Coupling of α-Ketoacids and Alcohols Mediated by Hypervalent Iodine(III)

  Takeshi Nanjo; Natsuki Kato; Yoshiji Takemoto

  Organic Letters, 31 Aug. 2018, Peer-reviewed, Lead author

  
• Remote, Late-Stage Oxidation of Aliphatic C–H Bonds in Amide-Containing Molecules

  Takeshi Nanjo; Emilio C. de Lucca; M. Christina White

  Journal of the American Chemical Society, 04 Oct. 2017, Peer-reviewed, Lead author

  
• Palladium-Catalyzed Double C–H Functionalization of Arenes at the Positions <i>ortho</i> and <i>meta</i> to Their Directing Group: Concise Synthesis of Benzocyclobutenes

  Takeshi Nanjo; Chihiro Tsukano; Yoshiji Takemoto

  CHEMICAL & PHARMACEUTICAL BULLETIN, 2016, Peer-reviewed, Lead author

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• Synthesis of 3,3-Disubstituted 2-Aminoindolenines by Palladium-Catalyzed Allylic Amidination with Isocyanide

  Yoshiji Takemoto; Takeshi Nanjo; Chihiro Tsukano

  Synlett, 30 Apr. 2014, Peer-reviewed, Lead author

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• Synthesis of 3-Acyl-2-arylindole via Palladium-catalyzed Isocyanide Insertion and Oxypalladation of Alkyne

  Takeshi Nanjo; Sho Yamamoto; Chihiro Tsukano; Yoshiji Takemoto

  Organic Letters, 03 Jul. 2013, Peer-reviewed, Lead author

  
• Palladium-Catalyzed Cascade Process Consisting of Isocyanide Insertion and Benzylic C(sp³)–H Activation: Concise Synthesis of Indole Derivatives

  Takeshi Nanjo; Chihiro Tsukano; Yoshiji Takemoto

  Organic Letters, 31 Jul. 2012, Peer-reviewed, Lead author

  
• Domino Pd‐Catalyzed Heck Cyclization and Bismuth‐Catalyzed Hydroamination: Formal Synthesis of Elacomine and Isoelacomine

  Haruhi Kamisaki; Takeshi Nanjo; Chihiro Tsukano; Yoshiji Takemoto

  Chemistry – A European Journal, 16 Nov. 2010, Peer-reviewed

  

Misc.

• 触媒的不斉Mannich反応を基盤としたβ-アミノ-α-ケト酸の新規合成法の開発と応用

  德弘 佑介; 吉川広祐; 村山聖; 南條毅; 竹本佳司

  創薬懇話会2021 in 京都, Jun. 2021, Peer-reviewed

  
• アミドの触媒的N-クロロ化を利用したデヒドロアミノ酸含有ペプチドの合成

  南條 毅; 大下 拓真; 竹本 佳司

  日本薬学会第141年会, Mar. 2021, Peer-reviewed

  
• ペプチドケト酸を用いた新規脱炭酸型フラグメント縮合法の開発

  南條 毅; 吉川 広祐; 德弘 佑介; 加藤 夏己; 竹本 佳司

  日本薬学会第141年会, Mar. 2021, Peer-reviewed

  
• キサントゲン酸塩を利用した脱酸素型C-C結合形成反応の開発

  南條 毅; 松ヶ迫 樹; 竹本 佳司

  日本薬学会第141年会, Mar. 2021, Peer-reviewed

  
• Mild and Chemoselective Amidation Enabled by Oxidative Decarboxylation of α-Ketoacids

  Takeshi Nanjo

  ACS-SBQ Virtual Meeting on Organis Synthesis and Catalysis, Nov. 2020, Peer-reviewed, Invited

  
• 脱炭酸を基盤とする化学選択的アシル化法の開発とペプチド合成への展開

  南條 毅

  第6回 関西薬学シンポジウム, Oct. 2020, Peer-reviewed, Invited

  
• 触媒的Mannich反応によるβ-アミノ-αケト酸類縁体の不斉合成

  德弘 佑介; 張 旋; 南條 毅; 竹本 佳司

  第49回 複素環化学討論会, Sep. 2020, Peer-reviewed

  
• ドミノ環化反応を基盤としたlyconesidine Bの全合成

  黒瀬 朋浩; 南條 毅; 塚野 千尋; 竹本 佳司

  第18回 次世代を担う有機化学シンポジウム, Aug. 2020, Peer-reviewed

  
• 温和な条件での単体硫黄の活性化を利用した化学選択的チオアミド化反応の開発

  斉藤 真人; 村上 翔; 南條 毅; 小林 祐輔; 竹本 佳司

  日本薬学会第140年会, Mar. 2020, Peer-reviewed

  
• 有機光触媒を用いたC1ユニット導入反応の開発

  松ヶ迫 樹; 南條 毅; 竹本 佳司

  日本薬学会第140年会, Mar. 2020, Peer-reviewed

  
• ペプチド合成を指向したβ-アミノ-α-ケト酸の触媒的不斉合成法の開発

  徳弘 佑介; 南條 毅; 竹本 佳司

  日本薬学会第140年会, Mar. 2020, Peer-reviewed

  
• Development of Chemoselective Thioamidation by Activation of Elemental Sulfur

  Masato Saito; Sho Murakami; Takeshi Nanjo; Yusuke Kobayashi; Yoshiji Takemoto

  第１２回有機触媒シンポジウム, Dec. 2019, Peer-reviewed

  
• Diastereodivergent Asymmetric Addition of Glyoxylate Cyanohydrin to Imines for the Synthesis of β-Amino Acid Analogues

  Yusuke Tokuhiro; Xuan Zhang; Takeshi Nanjo; Yoshiji Takemoto

  第１２回有機触媒シンポジウム, Dec. 2019, Peer-reviewed

  
• Photo-mediated Radical Addition to a Methylenehydrazine for the Introduction of C1 Unit

  Takeshi Nanjo; Tatsuki Matsugasako; Yoshiji Takemoto

  第１２回有機触媒シンポジウム, Dec. 2019, Peer-reviewed

  
• α-ケト酸を利用したアミンの化学選択的アシル化法の開発

  南條 毅; 加藤 夏己; 張 旋; 竹本 佳司

  第3７回 メディシナルケミストリーシンポジウム, Nov. 2019, Peer-reviewed

  
• 脱炭酸を基盤とする化学選択的アシル化法の開発

  南條 毅; 加藤 夏己; 張 旋; 竹本 佳司

  第45回 反応と合成の進歩シンポジウム, Oct. 2019, Peer-reviewed

  
• チオペプチド合成を指向した化学選択的チオアミド化反応の開発

  斉藤 真人; 村上翔; 南條 毅; 小林 祐輔; 竹本 佳司

  第45回 反応と合成の進歩シンポジウム, Oct. 2019, Peer-reviewed

  
• β-アミノ酸類縁体の分岐的合成を指向した高立体選択的Mannich反応の開発

  徳弘 佑介; 張 旋; 南條 毅; 竹本 佳司

  第69回 日本薬学会関西支部総会・大会, Oct. 2019, Peer-reviewed

  
• 効率的な1炭素増炭のための新規ヒドラゾン試薬の開発

  南條 毅; 松ヶ迫 樹; 竹本 佳司

  第69回 日本薬学会関西支部総会・大会, Oct. 2019, Peer-reviewed

  
• 単体硫黄の活性化を基盤とした化学選択的チオアミド化反応の開発

  斉藤 真人; 村上 翔; 南條 毅; 小林 祐輔; 竹本 佳司

  第69回 日本薬学会関西支部総会・大会, Oct. 2019, Peer-reviewed

  
• Catalytic asymmetric addition of glyoxylate cyanohydrin to imines for the divergent synthesis of α-keto/hydroxy β-amino acid analogues

  Xuan Zhang; Yusuke Tokuhiro; Takeshi Nanjo; Yoshiji Takemoto

  The 8th Japanese-Sino Symposium on Organic Chemistry for Young Scientists, Sep. 2019, Peer-reviewed

  
• α-ケト酸を用いたアミンの化学選択的アシル化法の開発

  南條 毅; 加藤 夏己; 張旋; 竹本 佳司

  第36回 有機合成化学セミナー, Sep. 2019, Peer-reviewed

  
• Chemoselective, Decarboxylative Acylation of Amines

  Takeshi Nanjo; Natsuki Kato; Xuan Zhang; Yoshiji Takemoto

  The 27th International Society of Heterocyclic Congress, Sep. 2019, Peer-reviewed

  
• Synthetic Studies of Lyconesidines Based on Domino Ring-Transformation Strategy

  Tomohiro Kurose; Takeshi Nanjo; Chihiro Tsukano; Yoshiji Takemoto

  The 27th International Society of Heterocyclic Congress, Sep. 2019, Peer-reviewed

  
• Organocatalyzed Enantioselective Addition of Glyoxylate Cyanohydrin to Imines for Divergent and Scalable Synthesis of α-Keto-β-Amino Acid Analogues

  Xuan Zhang; Yusuke Tokuhiro; Takeshi Nanjo; Yoshiji Takemoto

  The 27th International Society of Heterocyclic Congress, Sep. 2019, Peer-reviewed

  
• Hydroperoxide-Mediated Chemoselective, Decarboxylative Acylation of Amine

  Takeshi Nanjo; Natsuki Kato; Xuan Zhang; Yoshiji Takemoto

  The 4th International Symposium on Process Chemistry, Jul. 2019, Peer-reviewed

  
• Divergent and scalable synthesis of β-amino acid analogues by catalytic enantioselective addition of glyoxylate cyanohydrin to imines

  Xuan Zhang; Yusuke Tokuhiro; Takeshi Nanjo; Yoshiji Takemoto

  The 4th International Symposium on Process Chemistry, Jul. 2019, Peer-reviewed

  
• α-ケト酸を用いた化学選択的アミド縮合法の開発

  南條毅; 加藤夏己; 張旋; 竹本佳司

  第86回 日本分析化学会有機微量分析研究懇談会 第110回 計測自動制御学会力学量計測部会 第36回 合同シンポジウム, Jun. 2019, Peer-reviewed

  
• グリオキシル酸シアノヒドリンの不斉 Mannich 反応によるβ-アミノ酸誘導体の合成

  南條 毅; 張 旋; 徳弘 佑介; 竹本 佳司

  日本薬学会第139年会, Mar. 2019, Peer-reviewed

  
• 新規脱炭酸型アミド縮合法の開発とペプチド合成への適用

  南條 毅; 加藤 夏己; 張 旋; 竹本 佳司

  日本薬学会第139年会, Mar. 2019, Peer-reviewed

  
• α-ケト酸の脱炭酸型アミド縮合法の開発とペプチド合成への応用

  南條 毅; 張 旋; 加藤 夏己; 竹本 佳司

  第68回 近畿支部総会・大会, Oct. 2018, Peer-reviewed

  
• 超原子価ヨウ素によるα-ケト酸の脱炭酸型エステル化法の開発

  南條 毅; 加藤 夏己; 竹本 佳司

  第21回 ヨウ素学会シンポジウム, Sep. 2018, Peer-reviewed

  
• α-ケト酸の酸化的脱炭酸を利用したアミド化法の開発

  南條 毅; 張 旋; 竹本 佳司

  第38回 有機合成若手セミナー, Aug. 2018, Peer-reviewed

  
• α-ケト酸の酸化的脱炭酸を利用した新規エステル化反応の開発

  南條 毅; 加藤 夏己; 竹本 佳司

  日本薬学会第138年会, Mar. 2018, Peer-reviewed

  
• α-ケト酸の酸化的脱炭酸を利用した触媒的アミド化法の開発

  南條 毅; 竹本 佳司

  日本薬学会第138年会, Mar. 2018, Peer-reviewed

  
• 超原子価ヨウ素を用いたα-ケト酸の脱炭酸型縮合反応の開発

  南條 毅; 竹本 佳司

  第43回反応と合成の進歩シンポジウム, Nov. 2017, Peer-reviewed

  
• ノルボルネンを用いた連続的C-H活性化によるベンゾシクロブテンの合成

  南條 毅; 塚野千尋; 竹本佳司

  日本薬学会第135年会, Mar. 2015, Peer-reviewed

  
• C-H官能基化の実践的合成への応用を指向した配向基の探索

  塚野千尋; 織田拓也; 南條 毅; 竹本佳司

  日本薬学会第135年会, Mar. 2015, Peer-reviewed

  
• ノルボルネンを用いた芳香環の連続的C-H活性化

  南條 毅; 塚野千尋; 竹本佳司

  第64回日本薬学会近畿支部大会, Oct. 2014, Peer-reviewed

  
• Synthesis of Indole Derivatives by Palladium-Catalyzed Isocyanide Insertion

  Takeshi Nanjo; Sho Yamamoto; Chihiro Tsukano; Yoshiji Takemoto

  ICOMC2014, Jul. 2014, Peer-reviewed

  
• Pd触媒によるイソシアニドの挿入とアルキンのオキシパラデーションを利用した3-アシル-2-アリールインドール誘導体の合成

  南條 毅; 山本 翔; 塚野千尋; 竹本佳司

  第63回日本薬学会近畿支部大会, Oct. 2013, Peer-reviewed

  
• Palladium-catalyzed indole synthesis using isocyanide insertion

  Takeshi Nanjo; Chihiro Tsukano; Yoshiji Takemoto

  ISHHC-16, Aug. 2013, Peer-reviewed

  
• パラジウム触媒によるイソシアニドの挿入を利用したインドール誘導体の合成

  南條 毅; 山本 翔; 塚野千尋; 竹本佳司

  第11回次世代を担う有機化学シンポジウム, May 2013, Peer-reviewed

  
• Pd触媒によるイソシアニド、アルキンの連続的な挿入を利用したインドール誘導体の合成

  南條 毅; 山本 翔; 塚野千尋; 竹本佳司

  日本薬学会第133年会, Mar. 2013, Peer-reviewed

  
• π-アリルPd錯体に対するイソシアニドの挿入反応を利用した2位ヘテロ置換インドール誘導体の合成

  南條 毅; 塚野千尋; 竹本佳司

  日本薬学会第133年会, Mar. 2013, Peer-reviewed

  
• パラジウム触媒によるイソシアニドの挿入反応を利用したインドール合成法の開発

  南條 毅; 塚野千尋; 竹本佳司

  第42回複素環化学討論会, Oct. 2012, Peer-reviewed

  
• パラジウム触媒によるイソシアニドへの挿入・C(sp3)–H活性化プロセスを利用したインドール誘導体の合成

  南條 毅; 塚野千尋; 竹本佳司

  第59回有機金属討論会, Sep. 2012, Peer-reviewed

  
• パラジウム触媒によるイソシアニドの挿入・ベンジル位C(sp3)-H活性化プロセスを利用したインドール合成法の開発

  南條 毅; 塚野千尋; 竹本佳司

  第29回有機合成化学セミナー, Sep. 2012, Peer-reviewed

  
• パラジウム触媒による挿入-C-H活性化プロセスを利用したインドール合成法の開発

  南條 毅; 塚野千尋; 竹本佳司

  日本薬学会第132年会, Mar. 2012, Peer-reviewed

  
• パラジウム触媒によるC(sp3)–H官能基化を利用した2-置換インドール合成法の開発

  南條 毅; 塚野千尋; 竹本佳司

  第31回有機合成若手セミナー, Nov. 2011, Peer-reviewed

  
• パラジウム触媒によるC(sp3)-H官能基化を利用したインドール合成法の開発

  南條 毅; 塚野千尋; 竹本佳司

  第61回日本薬学会近畿支部大会, Oct. 2011, Peer-reviewed

  
• パラジウム触媒を用いたドミノ型環化反応によるジヒドロフロインドール骨格の新規合成法

  TSUKANO CHIHIRO; NANJO TAKESHI; TAKEMOTO YOSHIJI

  日本薬学会年会要旨集, Mar. 2011, Peer-reviewed

  
• ジエンのアミド化を経由するエラコミン類の全合成研究

  NANJO TAKESHI; KAMIZAKI HARUAKI; TSUKANO CHIHIRO; TAKEMOTO YOSHIJI

  日本薬学会年会要旨集, Mar. 2010, Peer-reviewed

  

Presentations

• 非天然型ペプチドの効率供給を目指した反応開発研究

  南條毅

  日本RXEフォーラム2024, 22 Aug. 2024, Invited

  
• 反応屋的思考に基づくペプチド合成技術の開発研究

  南條毅

  第11回BRIGHTシンポジウム, 18 Jun. 2024, Invited

  
• Oxidative Functionalization of Peptides Enabled by N-Chlorination of Amides

  南條毅

  柴崎コロキウム, 14 Jun. 2024, Invited

  
• Oxidative Functionalization of Peptides Enabled by Catalytic N-Chlorination of Amides

  Takeshi Nanjo

  9th Sino-Japanese Symposium on Organic Chemistry for Young Scientists, 08 Jun. 2024, Invited

  
• 化学選択的変換を基盤とした非天然型ペプチドの迅速合成法の開発

  南條毅

  日本薬学会第144年会, 29 Mar. 2024, Invited

  
• 非天然型ペプチドの合成を志向した新規反応開発

  南條毅

  第107回産総研触媒化学融合研究センター講演会, 16 Feb. 2024, Invited

  
• アミドのN-クロロ化を基軸とするペプチド変換法の開拓

  南條毅

  「生体適合化学の進歩」インタラクティブフォーラム 第18回ABC-InFO, 28 Sep. 2023, Invited

  
• Chemoselective decarboxylative transformation using α-ketoacids

  Takeshi Nanjo

  Joint Workshop on the Organic Chemistry of Sulfur (JWOCS-23), 28 Feb. 2023, Invited

  
• Oxidative Functionalization of Peptides Enabled by Catalytic N-Chlorination of Amides

  Takeshi Nanjo

  11th Singapore International Chemistry Conference, 14 Dec. 2022, Invited

  
• アミドのN-クロロ化を経由する非天然型ペプチド化合物の合成

  南條毅

  創薬等先端技術支援基盤プラットホーム（BINDS）第3回合成勉強会, 03 Sep. 2022, Invited

  
• Mild and Chemoselective Amidation Enabled by Oxidative Decarboxyltion of α-Ketoacids

  Takeshi Nanjo

  ACS-SBQ VMOSC, 24 Nov. 2020, Invited

  
• 脱炭酸を基盤とする化学選択的アシル化法の開発とペプチド合成への展開

  南條毅

  第6回関西薬学シンポジウム：化学系の若い力, 31 Oct. 2020, Invited

  
• 新規合成手法の開拓におけるデータベースとの付き合い方

  南條毅

  Reaxys活用事例ウェビナー, 29 Oct. 2020, Invited

  

External funds: Kakenhi

• Development of Chemoselective Decarboxylative Transformation for Unnatural Peptide Synthesis

  Grant-in-Aid for Early-Career Scientists

  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related

  Kyoto University

  Takeshi Nanjo

  From 01 Apr. 2020, To 31 Mar. 2022, Project Closed

  α-ケト酸;チオエステル;脱炭酸;不斉合成;N-クロロアミド;ペプチド;デヒドロアミノ酸;ラジカル;単体硫黄;光反応;Mannich反応;N-クロロ化;チオアミド;不斉付加反応;バイオイソスター

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K15954/
• The development of oxidative decarboxylation for efficient synthesis of complex molecules

  Grant-in-Aid for Early-Career Scientists

  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related

  Kyoto University

  Takeshi Nanjo

  From 01 Apr. 2018, To 31 Mar. 2020, Project Closed

  エステル;アミド;ペプチド;チオアミド;α-ケト酸;脱炭酸;有機触媒;不斉合成;フラグメント縮合;ヒドロペルオキシド;不斉有機触媒;超原子価ヨウ素;糖;酸化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K14865/
• Development of Peptide Chemical Modification Enabled by N-Halogenation of Amides

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related

  Kyoto University

  南條 毅

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  N-クロロアミド;ペプチド;Late-Stage官能基化;縮合;N-ハロゲン化;化学修飾;有機触媒

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H02743/
• Development of Peptide Chemical Modification Enabled by N-Halogenation of Amides

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related

  Kyoto University

  南條 毅

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  N-クロロアミド;ペプチド;Late-Stage官能基化;縮合;N-ハロゲン化;化学修飾;有機触媒

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K24006/

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  Advanced Organic Chemistry for Drug Discovery A

  8203, Fall, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  4201, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Advanced Basic Organic Chemistry I

  1209, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Basic Laboratory Techniques in Organic Chemistry

  1205, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Introduction to Organic Chemistry for Drug Discovery

  1026, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Advanced Pharmaceutical Sciences I

  6005, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Introduction to Pharmaceutical Sciences

  6002, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar in Basic Medicinal and Organic Chemistry

  2301, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Introduction to Organic Chemistry for Drug Discovery

  8102, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Research in Basic Medicinal and Organic Chemistry

  3201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Fundamental Chemical Experiments

  N308, Fall, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  4201, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Basic Medicinal and Organic Chemistry

  2301, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Basic Medicinal and Organic Chemistry

  3201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  4201, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Basic Medicinal and Organic Chemistry

  3201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory 2 : Organic Chemistry

  A902, Spring, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Basic Medicinal and Organic Chemistry

  2301, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  4201, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Basic Medicinal and Organic Chemistry

  3201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory 2 : Organic Chemistry

  A902, Spring, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Basic Medicinal and Organic Chemistry

  2301, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From Apr. 2020, To Mar. 2021

  ILAS Seminar :Organic Chemistry of Pharmaceuticals

  Spring, 全学共通科目
• From Apr. 2020, To Mar. 2021

  Organic Chemistry Exercise 2

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Organic Chemistry Seminar

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory II : Organic Chemistry

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory 2 : Organic Chemistry

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Organic Chemistry Exercise 2

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Organic Chemistry Seminar

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Laboratory Practice in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Basic Medicinal and Organic Chemistry

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Fundamental Chemical Experiments

  Fall, 全学共通科目
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory II : Organic Chemistry

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory 2 : Organic Chemistry

  Spring, 薬学部

Administration

Faculty management (title, position)

• From 01 Apr. 2021, To 31 Mar. 2022

  NMR運営管理委員会　委員
• From 01 Apr. 2019, To 31 Mar. 2023

  質量分析運営委員会　委員
• From 01 Apr. 2020, To 31 Mar. 2021

  環境・安全衛生委員会　委員

Academic, Social Contribution

Social Contribution

• 滋賀県立膳所高等学校学校設定教科「探究」

  Lecturer

  From 31 Aug. 2023, To 31 Aug. 2023