Search for faculty members
Mizuta, Ken
Graduate School of Medicine, Medicine Assistant Professor
list
Last Updated :2025/05/30
Basic Information
Faculty
Professional Memberships
Academic Degree
Research History
- From Dec. 2009, To Mar. 2015Nara Medical University, Cardiovascular System Research Laboratory, Advanced Medical Research Center, Research Asistant
- From Apr. 2021, To PresentKyoto University, Department of Anatomy and Cell Biology, Graduate School of Medicine, Assistant Professor
- From Apr. 2019, To Mar. 2021Japan Society for the Promotion of Science, Research Fellow DC1
- From Apr. 2017, To Mar. 2018Rinku General Medical Center, Department of Anesthesia, Clinical Fellow
- From Apr. 2015, To Mar. 2017Kyoto University Hospital, Resident
Profile
Profile
2017年 日本周術期経食道心エコー認定医（JB-POT）試験 合格
2018年 麻酔科標榜医・認定医 取得
ID,URL
ORCID ID
J-Global ID
Researcher number
40909503
researchmap URL
list
Last Updated :2025/05/30
Research
Research Areas
Papers
- Atlas of Cynomolgus Macaque HematopoiesisShinichiro Oshima; Rahul Sinha; Kazuhiro Takeuchi; Ken Mizuta; Tomonori Nakamura; Ryoji Ito; Ikuo Kawamoto; Chizuru Iwatani; Masataka Nakaya; Hideaki Tsuchiya; Shruti Bhagat; Tomoyuki Tsukiyama; Akifumi Takaori-Kondo; Mitinori Saitou; Yasuhiro Murakawa; Ryo Yamamoto26 Apr. 2024
- Expression pattern of Runt-related transcription factor (RUNX) family members and the role of RUNX1 during kidney developmentKeiko Yano-Sakamoto; Yuichiro Kitai; Naoya Toriu; Shinya Yamamoto; Ken Mizuta; Mitinori Saitou; Tomoyuki Tsukiyama; Ichiro Taniuchi; Motomi Osato; Motoko YanagitaBiochemical and Biophysical Research Communications, Aug. 2024
- In vitro reconstitution of epigenetic reprogramming in the human germ lineYusuke Murase; Ryuta Yokogawa; Yukihiro Yabuta; Masahiro Nagano; Yoshitaka Katou; Manami Mizuyama; Ayaka Kitamura; Pimpitcha Puangsricharoen; Chika Yamashiro; Bo Hu; Ken Mizuta; Kosuke Ogata; Yasushi Ishihama; Mitinori SaitouNature, 20 May 2024
- Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cellsHiraku Tsujimoto; Azusa Hoshina; Shin-Ichi Mae; Toshikazu Araoka; Wang Changting; Yoshihiro Ijiri; May Nakajima-Koyama; Satoko Sakurai; Kazusa Okita; Ken Mizuta; Akira Niwa; Megumu K. Saito; Mitinori Saitou; Takuya Yamamoto; Cecilia Graneli; Kevin J. Woollard; Kenji OsafuneCell Reports, Jan. 2024, Peer-reviewed
- Key mechanisms and in vitro reconstitution of fetal oocyte development in mammalsKen Mizuta; Mitinori SaitouCurrent Opinion in Genetics & Development, Oct. 2023, Peer-reviewed, Lead author, Corresponding author
- Induction of fetal meiotic oocytes from embryonic stem cells in cynomolgus monkeysSayuri Gyobu‐Motani; Yukihiro Yabuta; Ken Mizuta; Yoshitaka Katou; Ikuhiro Okamoto; Masanori Kawasaki; Ayaka Kitamura; Tomoyuki Tsukiyama; Chizuru Iwatani; Hideaki Tsuchiya; Taro Tsujimura; Takuya Yamamoto; Tomonori Nakamura; Mitinori SaitouThe EMBO Journal, 16 Mar. 2023, Peer-reviewed
- Ex vivo reconstitution of fetal oocyte development in humans and cynomolgus monkeysKen Mizuta; Yoshitaka Katou; Baku Nakakita; Aoi Kishine; Yoshiaki Nosaka; Saki Saito; Chizuru Iwatani; Hideaki Tsuchiya; Ikuo Kawamoto; Masataka Nakaya; Tomoyuki Tsukiyama; Masahiro Nagano; Yoji Kojima; Tomonori Nakamura; Yukihiro Yabuta; Akihito Horie; Masaki Mandai; Hiroshi Ohta; Mitinori SaitouThe EMBO Journal, 15 Sep. 2022, Peer-reviewed, Lead author
- Nucleome programming is required for the foundation of totipotency in mammalian germline developmentMasahiro Nagano; Bo Hu; Shihori Yokobayashi; Akitoshi Yamamura; Fumiya Umemura; Mariel Coradin; Hiroshi Ohta; Yukihiro Yabuta; Yukiko Ishikura; Ikuhiro Okamoto; Hiroki Ikeda; Naofumi Kawahira; Yoshiaki Nosaka; Sakura Shimizu; Yoji Kojima; Ken Mizuta; Tomoko Kasahara; Yusuke Imoto; Killian Meehan; Roman Stocsits; Gordana Wutz; Yasuaki Hiraoka; Yasuhiro Murakawa; Takuya Yamamoto; Kikue Tachibana; Jan‐Michel Peters; Leonid A Mirny; Benjamin A Garcia; Jacek Majewski; Mitinori SaitouThe EMBO Journal, 04 Jul. 2022, Peer-reviewed
- Intensified hemodialysis for complicated pregnancy in a primigravida with advanced maternal age: a case report with literature review focusing on appropriate hemodialysis management during pregnancyHiroyuki Arai; Keita P. Mori; Hideki Yokoi; Ken Mizuta; Jumpei Ogura; Ko Suginami; Tomomi Endo; Yoshihiro Ikeda; Takeshi Matsubara; Tatsuo Tsukamoto; Motoko YanagitaRenal Replacement Therapy, Dec. 2020, Peer-reviewed
- TMEM100: A Novel Intracellular Transmembrane Protein Essential for Vascular Development and Cardiac MorphogenesisKen Mizuta; Masahide Sakabe; Satoshi Somekawa; Yoshihiko Saito; Osamu NakagawaEtiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology, 2016, Peer-reviewed, Lead author
- Cover ImageKen Mizuta; Masahide Sakabe; Aya Hashimoto; Tomoko Ioka; Chihiro Sakai; Kazuki Okumura; Miwa Hattammaru; Masahide Fujita; Mutsumi Araki; Satoshi Somekawa; Yoshihiko Saito; Osamu NakagawaDevelopmental Dynamics, Jan. 2015, Peer-reviewed, Lead author
- Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryos.Ken Mizuta; Masahide Sakabe; Aya Hashimoto; Tomoko Ioka; Chihiro Sakai; Kazuki Okumura; Miwa Hattammaru; Masahide Fujita; Mutsumi Araki; Satoshi Somekawa; Yoshihiko Saito; Osamu NakagawaDevelopmental dynamics : an official publication of the American Association of Anatomists, Jan. 2015, Peer-reviewed, Lead author
- An important role of endothelial hairy-related transcription factors in mouse vascular development.Takashi Morioka; Masahide Sakabe; Tomoko Ioka; Tomoko Iguchi; Ken Mizuta; Miwa Hattammaru; Chihiro Sakai; Munehiro Itoh; Genki E Sato; Aya Hashimoto; Masahide Fujita; Kazuki Okumura; Mutsumi Araki; Mei Xin; Roger A Pedersen; Manuel F Utset; Hiroshi Kimura; Osamu NakagawaGenesis (New York, N.Y. : 2000), Nov. 2014, Peer-reviewed
- Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.Satoshi Somekawa; Keiichi Imagawa; Hisaki Hayashi; Masahide Sakabe; Tomoko Ioka; Genki E Sato; Ken Inada; Takaaki Iwamoto; Toshio Mori; Shiro Uemura; Osamu Nakagawa; Yoshihiko SaitoProceedings of the National Academy of Sciences of the United States of America, 24 Jul. 2012, Peer-reviewed
Misc.
- In vitro reconstitution of human germ-cell developmentKen Mizuta; Mitinori Saitou実験医学, Jan. 2024, Invited, Lead author, Corresponding author
- 動脈形成に関与する新規BMP9/BMP10依存的血管内皮遺伝子の同定染川 智; 坂部 正英; 林 寿来; 稲田 賢; 佐藤 玄基; 上村 史朗; 中川 修; 斎藤 能彦血管, Oct. 2013
- Ex vivo reconstitution of fetal oocyte development in humansKen MIZUTA; Hiroshi OHTA; Mitinori SAITOU医学のあゆみ, 08 Apr. 2023, Invited, Lead author, Corresponding author
- Mechanisms and in vitro reconstitution of human germ-cell developmentKen Mizuta; Yoshitaka Katou; Hiroshi Ohta; Mitinori SaitouThe CELL, Jan. 2023, Invited, Lead author, Corresponding author
- Essential Function of Tmem100 for Endothelial Differentiation and Vascular Development Downstream of ALK1 SignalingSatoshi Somekawa; Masahide Sakabe; Hisaki Hayashi; Genki E. Sato; Ken Inada; Munehiro Ito; Shiro Uemura; Osamu Nakagawa; Yoshihiko SaitoCIRCULATION, Nov. 2012
- Tmem100, a Novel BMP9/10-Dependent Endothelial Gene Essential for Arterial Development and MorphogenesisSatoshi Somekawa; Hisaki Hayashi; Masahide Sakabe; Tomoko Ioka; Genki Sato; Ken Inada; Shiro Uemura; Osamu Nakagawa; Yoshihiko SaitoCIRCULATION, Nov. 2011
Presentations
- Efficient Ex Vivo Reconstitution of Fetal Oocyte Development in Humans and Cynomolgus MonkeysKen MizutaGordon Research Conference, 29 Apr. 2025
- ヒトおよびカニクイザル卵母細胞発生過程の体外再構成水田賢繁殖生物学会, 25 Sep. 2023, Invited
- Ex vivo reconstitution of fetal oocyte development in humans and cynomolgus monkeysKen Mizuta; Yoshitaka Katou; Baku Nakakita; Aoi Kishine; Chizuru Iwatani; Hideaki Tsuchiya; Ikuo Kawamoto; Masataka Nakaya; Tomoyuki Tsukiyama; Masahiro Nagano; Tomonori Nakamura; Yukihiro Yabuta; Hiroshi Ohta; Mitinori SaitouThe 21st Takeda Science Foundation Symposium on Bioscience, 27 Jan. 2023
- ヒト及びカニクイザル胎児の卵母細胞発生過程の体外再構成水田 賢第45回日本分子生物学会年会, 02 Dec. 2022
- Ex vivo reconstitution of fetal oocyte development in humans and monkeysKen MizutaThe 26th ASHBi Colloquium, 28 Jun. 2022
- In vitro derivation of primary oocytes from fetal germ cells in cynomolgus monkeyMizuta K; Ohta H; Nakamura T; Kishine A; Iwatani C; Tsuchiya H; Saitou MASHBi Retreat, 07 Feb. 2020
- 吐血を主訴とした二次性大動脈十二指腸瘻の一例水田 賢; 福田 晃久; 三上 哲平; 三嶋 眞紗子; 塩川 雅広; 高橋 健; 松浦 稔; 妹尾 浩第96回 日本消化器内視鏡学会近畿支部例会, Jun. 2016
- 妊娠初期からの頻回長時間透析で良好な胎児発育を得た、長期透析・高齢初産婦の一例水田 賢; 森 慶太; 横井 秀基; 平木 秀輔; 小椋 淳平; 杉並 興; 松原 雄; 塚本 達雄; 柳田 素子第29回 京都透析症例検討会, May 2016
- 心臓形態形成における新規BMP-ALK1系下流因子の役割とその作用メカニズム水田 賢第3回 医学研究学生フォーラム, Dec. 2014
- Tmem100, a novel intracellular transmembrane protein, regulates endothelial-mesenchymal transformation during endocardial cushion development.Mizuta K; Sakabe M; Hashimoto A; Iwata N; Ioka T; Morioka T; Hattammaru M; Fujita M; Kinoshita Y; Sakai C; Hayashi H; Somekawa S; Saito Y; Nakagawa OThe 7th TAKAO International Symposium, Jul. 2013
- Tmem100, a novel intracellular transmembrane protein, regulates endothelial-mesenchymal transformation during cardiac cushion development.Mizuta K; Sakabe M; Somekawa S; Fujita T; Ioka T; Hashimoto A; Sato G; Morioka T; Ito M; Hattanmaru M; Hayashi H; Saito Y; Nakagawa O第 77 回日本循環器学会学術集会, Mar. 2013
- 心血管系の形態形成・機能維持におけるBMPシグナルと新規下流因子の作用メカニズムの解明水田 賢; 佐藤 玄基文部科学省 第１回サイエンス・インカレ, Feb. 2012
- Tmem100, a novel intracellular transmembrane protein, regulates endocardial cushion formation in cardiac development.Mizuta K; Sakabe M; Somekawa S; Fujita T; Ioka T; Sato G; Morioka T; Ito M; Hayashi H; Saito Y; Nakagawa O第 34 回日本分子生物学会年会, Dec. 2011
Books and Other Publications
- Developmental Biology, 13th Edition阿形清和; 高橋淑子, Joint translation, 第14章 ヒト初期胚発生メディカル・サイエンス・インターナショナル, 31 Mar. 2025
Industrial Property Rights
Media Coverage
- 霊長類で世界初、サルのＥＳ細胞から卵子になる「卵母細胞」を作成…京大チームが発表讀賣新聞, Apr. 2023, Paper
- ヒト胎児の細胞から「卵子のもと」培養 京都大学のグループ成功京都新聞, Aug. 2022, Paper
- 胎児細胞から卵子のもと…「原始卵胞」の培養に京大など成功讀賣新聞, Aug. 2022, Paper
- 京大、原始卵胞の体外培養に成功 不妊症など解明に道日刊工業新聞, Aug. 2022, Paper
- ヒト胎児細胞から「卵子のもと」 体外で作製成功、不妊治療に期待 京大教授のチーム朝日新聞, Aug. 2022, Paper
- 人の胎児細胞から「卵子のもと」 京都大、不妊治療に道日本経済新聞, Aug. 2022, Paper
- “胎児の細胞から卵子のもとの作製に成功”と発表 京大などNHK, Aug. 2022, Media report
External funds: Kakenhi
- Efficient ex vivo reconstitution of fetal oocyte development in primatesGrant-in-Aid for Research Activity Start-up0802:Biomedical structure and function and related fieldsKyoto UniversityKen MizutaFrom 30 Aug. 2021, To 31 Mar. 2023, Project Closed生殖細胞;霊長類;カニクイザル;胎児;体外培養;卵母細胞;原始卵胞;減数分裂;再構成卵巣
- カニクイザル多能性幹細胞を起点とする卵母細胞発生過程の試験管内再構成Grant-in-Aid for Early-Career ScientistsBasic Section 48010:Anatomy-relatedKyoto University水田 賢From 01 Apr. 2024, To 31 Mar. 2027, Grantedカニクイザル;多能性幹細胞;卵母細胞;試験管内培養;生殖細胞
