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Arichi, Norihito
Graduate School of Pharmaceutical Sciences, Division of Bioinformatics and Chemical Genomics Assistant Professor
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Last Updated :2025/05/02
Basic Information
Faculty
Academic Degree
High School
High School
洛南高等学校
Research History
- From Feb. 2021, To PresentKyoto University, Graduate School of Pharmaceutical Sciences, 助教
- From Feb. 2019, To Jan. 2021田辺三菱製薬株式会社, 研究員
- From Jul. 2015, To Jan. 2019ケンブリッジ大学, 博士研究員
- From Apr. 2015, To Jun. 2015Kyoto University, Graduate School of Pharmaceutical Sciences, 博士研究員
Language of Instruction
ID,URL
ORCID ID
J-Global ID
researchmap URL
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Last Updated :2025/05/02
Research
Research Topics, Overview of the research
Research Topics
Synthesis of biologically active molecules and development of novel synthetic methodologiesOverview of the research
My research is focused on the synthesis of biologically active complex molecules and the development of novel synthetic methodologies to build structural motifs that are difficult to access via conventional approaches.
Papers
- Visible light-mediated photocatalytic coupling between tetrazoles and carboxylic acids for biomolecule labelling.Takuro Matsuoka; Ryosuke Takasaki; Hiroki Akiba; Kosuke Ogata; Akira Hattori; Norihito Arichi; Hideaki Kakeya; Sho Yamasaki; Yasushi Ishihama; Hiroaki Ohno; Shinsuke InukiChemical communications (Cambridge, England), 01 Apr. 2025
- Receptor-independent regulation of Gα13 by alpha-1-antitrypsin C-terminal peptidesYonghak Park; Shigeyuki Matsumoto; Kosuke Ogata; Biao Ma; Ryo Kanada; Yuta Isaka; Norihito Arichi; Xiaowen Liang; Ritsuko Maki; Tohru Kozasa; Yasushi Okuno; Hiroaki Ohno; Yasushi Ishihama; Fumiko ToyoshimaJournal of Biological Chemistry, Dec. 2024
- Development of Ribityllumazine Analogue as Mucosal-Associated Invariant T Cell Ligands.Ryosuke Takasaki; Emi Ito; Masamichi Nagae; Yuki Takahashi; Takuro Matsuoka; Wakana Yasue; Norihito Arichi; Hiroaki Ohno; Sho Yamasaki; Shinsuke InukiJournal of the American Chemical Society, 21 Oct. 2024
- Approach to Spirocyclohexadienes via Visible Light‐Mediated ipso‐Cyclization of Amino Acid Derivatives with N‐(2‐Phenyl)benzoyl GroupsYuki Yoshida; Haruka Takeuchi; Norihito Arichi; Shinya Oishi; Hiroaki Ohno; Shinsuke InukiAsian Journal of Organic Chemistry, 28 May 2024
- Construction of the Akuammiline Alkaloid Core Structure via Stereoselective E-Ring Formation.Naoki Hashimoto; Junichi Taguchi; Takumi Kasagi; Norihito Arichi; Shinsuke Inuki; Hiroaki OhnoThe Journal of organic chemistry, 01 Jul. 2024
- Synthesis of Sulfilimines via Visible-Light-Mediated Triplet Energy Transfer to Sulfonyl Azides.Norihito Arichi; Tsuyoshi Amano; Shuhan Wu; Shinsuke Inuki; Hiroaki OhnoChemistry (Weinheim an der Bergstrasse, Germany), 24 Jun. 2024
- Gold(I)-Catalyzed Cascade Cyclization of Alkynyl Indoles for the Stereoselective Construction of the Quaternary Carbon Center of Akuammiline AlkaloidsHashimoto, N.; Taguchi, J.; Arichi, N.; Inuki, S.; Ohno, H.Journal of Organic Chemistry, 2023
- Synthesis of labionin and avionin precursors via a nitrogen-centred-radical-triggered 1,5-HAT reaction of Tris derivatives.Ayuta Yamaguchi; Naoki Obiya; Norihito Arichi; Shinya Oishi; Hiroaki Ohno; Shinsuke InukiOrganic & biomolecular chemistry, 06 Mar. 2024
- Gold(I)‐Catalyzed Bis‐Cyclization of Allenynes for the Synthesis of Strained and Planar Polycyclic CompoundsHitomi Tsuno; Jingfeng Shen; Hiroki Komatsu; Norihito Arichi; Shinsuke Inuki; Hiroaki OhnoAngewandte Chemie International Edition, 28 Aug. 2023, Peer-reviewed
- Construction of a Bicyclo[2.2.2]octene Skeleton via a Visible-Light-Mediated Radical Cascade Reaction of Amino Acid Derivatives with N-(2-Phenyl)benzoyl GroupsYuki Yoshida; Haruka Takeuchi; Kohei Nakagawa; Toshiki Fujii; Norihito Arichi; Shinya Oishi; Hiroaki Ohno; Shinsuke InukiOrganic Letters, 07 Jul. 2023, Peer-reviewed
- Alkoxymigration onto α‐Imino Gold Carbenes for Constructing Propellane‐Type IndolinesLuca C. Greiner; Norihito Arichi; Shinsuke Inuki; Hiroaki OhnoAsian Journal of Organic Chemistry, Jul. 2023
- Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands.Takuro Matsuoka; Akira Hattori; Shinya Oishi; Mitsugu Araki; Biao Ma; Toshiki Fujii; Norihito Arichi; Yasushi Okuno; Hideaki Kakeya; Sho Yamasaki; Hiroaki Ohno; Shinsuke InukiJournal of medicinal chemistry, 14 Sep. 2023
- Archaeal Glycerolipids Are Recognized by C-Type Lectin Receptor Mincle.Shiori Oka; Miyuki Watanabe; Emi Ito; Ami Takeyama; Takuro Matsuoka; Masatomo Takahashi; Yoshihiro Izumi; Norihito Arichi; Hiroaki Ohno; Sho Yamasaki; Shinsuke InukiJournal of the American Chemical Society, 23 Aug. 2023
- Gold(I)‐Catalyzed Benzylic C(sp 3 )−H Functionalizations: Divergent Synthesis of Indole[ a ]‐ and [ b ]‐Fused PolycyclesLuca C. Greiner; Norihito Arichi; Shinsuke Inuki; Hiroaki OhnoAngewandte Chemie International Edition, 16 Jan. 2023, Peer-reviewed
- Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I)Atsuhito Tsuji; Takahiro Masuya; Norihito Arichi; Shinsuke Inuki; Masatoshi Murai; Hideto Miyoshi; Hiroaki OhnoACS Medicinal Chemistry Letters, 24 Jan. 2023
- Construction of Tricyclic Nitrogen Heterocycles by a Gold(I)‐Catalyzed Cascade Cyclization of Allenynes and Application to Polycyclic π‐Electron SystemsHiroki Komatsu; Takaya Ikeuchi; Hitomi Tsuno; Norihito Arichi; Kosuke Yasui; Shinya Oishi; Shinsuke Inuki; Aiko Fukazawa; Hiroaki OhnoAngewandte Chemie International Edition, 20 Dec. 2021
- Front Cover: Access to Indole‐Fused Benzannulated Medium‐Sized Rings through a Gold(I)‐Catalyzed Cascade Cyclization of Azido‐Alkynes (Chem. Eur. J. 51/2021)Luca C. Greiner; Shinsuke Inuki; Norihito Arichi; Shinya Oishi; Rikito Suzuki; Tomohiro Iwai; Masaya Sawamura; A. Stephen K. Hashmi; Hiroaki OhnoChemistry – A European Journal, 09 Sep. 2021
- Access to Indole‐Fused Benzannulated Medium‐Sized Rings through a Gold(I)‐Catalyzed Cascade Cyclization of Azido‐AlkynesLuca C. Greiner; Shinsuke Inuki; Norihito Arichi; Shinya Oishi; Rikito Suzuki; Tomohiro Iwai; Masaya Sawamura; A. Stephen K. Hashmi; Hiroaki OhnoChemistry – A European Journal, 09 Sep. 2021
- Synthesis and biological evaluation of steroidal derivatives bearing a small ring as vitamin D receptor agonistsArichi, N.; Fujiwara, S.; Ishizawa, M.; Makishima, M.; Hua, D.H.; Yamada, K.-I.; Yamaoka, Y.; Takasu, K.Bioorganic and Medicinal Chemistry Letters, 2017
- An arylative ring expansion cascade of fused cyclobutenes via short-lived intermediates with planar chiralityArichi, N.; Yamada, K.-I.; Yamaoka, Y.; Takasu, K.Journal of the American Chemical Society, 2015
- Synthesis of steroidal derivatives bearing a small ring using a catalytic [2+2] cycloaddition and a ring-contraction rearrangementArichi, N.; Hata, K.; Takemoto, Y.; Yamada, K.-I.; Yamaoka, Y.; Takasu, K.Tetrahedron, 2015
- Equilibration of the [2+2] Cycloaddition of Silyl Enol Ethers Catalyzed by Ethylaluminium Dichloride: Diastereoselectivity Switch in the Synthesis of Fused CyclobutanesHata, K.; Arichi, N.; Yamaoka, Y.; Yamada, K.-I.; Takemoto, Y.; Takasu, K.Asian Journal of Organic Chemistry, 2014
- Strand breakage of a (6-4) photoproduct-containing DNA at neutral pH and its repair by the ERCC1-XPF protein complexArichi, N.; Yamamoto, J.; Takahata, C.; Sano, E.; Masuda, Y.; Kuraoka, I.; Iwai, S.Organic and Biomolecular Chemistry, 2013
- Mechanism of the alkali degradation of (6-4) photoproduct-containing DNAArichi, N.; Inase, A.; Eto, S.; Mizukoshi, T.; Yamamoto, J.; Iwai, S.Organic and Biomolecular Chemistry, 2012
Misc.
- Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine of Avionin Moiety and Synthetic Study of Microvionin山口亞由太; 井貫晋輔; 有地法人; 大石真也; 大野浩章日本薬学会年会要旨集(Web), 2023
- Construction of Bicyclo[2.2.2]octene Skeleton through Visible-Light-Mediated Photocatalytic Dearomatization吉田悠生; 井貫晋輔; 竹内春佳; 中川航平; 有地法人; 大石真也; 大野浩章日本薬学会年会要旨集(Web), 2023
- Identification of a novel MR1 ligand by screening with split-luciferase and its structure-activity relationship study松岡巧朗; 服部明; 大石真也; 有地法人; 掛谷秀昭; 山崎晶; 山崎晶; 大野浩章; 井貫晋輔メディシナルケミストリーシンポジウム講演要旨集, 2022
- 金触媒連続環化反応を用いたアクアミリンアルカロイド類の合成研究橋本直季; 田口淳一; 有地法人; 大石真也; 井貫晋輔; 大野浩章反応と合成の進歩シンポジウム講演要旨集, 2021
- 分子ひずみを持つ中員環の化学高須清誠; 有地法人ファルマシア(Web), 2021
- 面性不斉短寿命中間体を経る縮環シクロブテンの環拡大反応有地法人; 山田健一; 山岡庸介; 高須清誠日本薬学会年会要旨集(CD-ROM), 2015
- 面性不斉短寿命中間体を経由する縮環シクロブテンの環拡大反応有地法人; 山田健一; 山岡庸介; 高須清誠シンポジウム「モレキュラー・キラリティー」講演要旨集, 2015
- D環側鎖の配座制御を志向した小員環を有するエストロン誘導体の合成有地法人; 山岡庸介; 山田健一; 高須清誠日本薬学会年会要旨集(CD-ROM), 2013
- D環側鎖の配座制御を志向した小員環を有するステロイド類の合成有地法人; 畑健二; 山田健一; 山岡庸介; 高須清誠有機合成シンポジウム講演要旨集, 2013
External funds: Kakenhi
- Decarboxylative [3+2] cycloaddition for the Synthesis of Hetisine-Type AlkaloidsGrant-in-Aid for Research Activity Start-up0801:Pharmaceutical sciences and related fieldsKyoto UniversityNorihito ArichiFrom 30 Aug. 2021, To 31 Mar. 2023, Project Closed可視光レドックス触媒;脱炭酸;ラジカル;アルカロイド;全合成;[3+2]環化付加
- 可視光レドックス触媒による炭素-炭素結合切断を利用した分子骨格の構築と変換Grant-in-Aid for Early-Career ScientistsBasic Section 47010:Pharmaceutical chemistry and drug development sciences-relatedKyoto University有地 法人From 01 Apr. 2022, To 31 Mar. 2025, Granted可視光レドックス触媒;ラジカル;アジド;結合切断;骨格変換
- Natural product syntheses based on cascade cyclization and their applications to middle-molecule drug modalitiesGrant-in-Aid for Scientific Research (B)Basic Section 47010:Pharmaceutical chemistry and drug development sciences-relatedKyoto University大野 浩章From 01 Apr. 2023, To 31 Mar. 2027, Grantedアルカロイド;連続反応;金触媒;中分子;ケミカルスペース
- Natural product syntheses based on cascade cyclization and their applications to middle-molecule drug modalitiesGrant-in-Aid for Scientific Research (B)Basic Section 47010:Pharmaceutical chemistry and drug development sciences-relatedKyoto University大野 浩章From 01 Apr. 2023, To 31 Mar. 2027, Grantedアルカロイド;連続反応;金触媒;中分子;ケミカルスペース
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Last Updated :2025/05/02
Education
Teaching subject(s)
- From 01 Apr. 2024, To 31 Mar. 2025Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Research Proposal Writing Practice B8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Organic Chemistry Exercise 2A018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2024, To 31 Mar. 2025Organic Chemistry SeminarC018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research B8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research C8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Pharmaceutical Laboratory II : Organic ChemistryC902, Spring, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2024, To 31 Mar. 2025Seminar on Critical Reading of Scientific Papers B8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2024, To 31 Mar. 2025Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice B8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory II : Organic ChemistryC902, Spring, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory 2 : Organic ChemistryA902, Spring, Faculty of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Skill Development for Lead Discovery5102, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research B8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers B8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Organic Chemistry Exercise 2A018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Organic Chemistry SeminarC018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Organic Chemistry Exercise 2A018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Skill Development for Lead Discovery5102, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023ILAS SeminarZ001, Spring, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Fundamental Chemical ExperimentsN308, Fall, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Organic Chemistry SeminarC018, Spring, Faculty of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Medical Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory 2 : Organic ChemistryA902, Spring, Faculty of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory II : Organic ChemistryC902, Spring, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2022, To 31 Mar. 2023Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From Apr. 2021, To Mar. 2022Organic Chemistry Exercise 2Spring, 薬学部
- From Apr. 2021, To Mar. 2022Organic Chemistry SeminarSpring, 薬学部
- From Apr. 2021, To Mar. 2022Skill Development for Lead DiscoveryYear-long, 薬学研究科
- From Apr. 2021, To Mar. 2022Pharmaceutical Laboratory II : Organic ChemistrySpring, 薬学部
- From Apr. 2021, To Mar. 2022Pharmaceutical Laboratory 2 : Organic ChemistrySpring, 薬学部
