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Fagarasan, Sidonia

Graduate School of Medicine Program-Specific Professor

Fagarasan, Sidonia
list
    Last Updated :2022/05/14

    Basic Information

    Academic Degree

    • M.D.(Iuliu Hatieganu University of Medicine and Pharmacy)
    • Ph.D.(Kyoto University)

    Language of Instruction

    • English

    ID,URL

    researchmap URL

    list
      Last Updated :2022/05/14

      Research

      Research Areas

      • Life sciences, Immunology

      Papers

      • Circulation of gut-preactivated naïve CD8+T cells enhances antitumor immunity in B cell-defective mice
        Maryam Akrami; Rosemary Menzies; Kenji Chamoto; Michio Miyajima; Ryuji Suzuki; Hiroyuki Sato; Akiko Nishii; Michio Tomura; Sidonia Fagarasan; Tasuku Honjo
        Proceedings of the National Academy of Sciences, 22 Sep. 2020
      • Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy.
        Ryusuke Hatae; Kenji Chamoto; Young Hak Kim; Kazuhiro Sonomura; Kei Taneishi; Shuji Kawaguchi; Hironori Yoshida; Hiroaki Ozasa; Yuichi Sakamori; Maryam Akrami; Sidonia Fagarasan; Izuru Masuda; Yasushi Okuno; Fumihiko Matsuda; Toyohiro Hirai; Tasuku Honjo
        JCI insight, 30 Jan. 2020, Peer-reviewed
      • Microbiota - an amplifier of autoimmunity.
        Vogelzang A; Guerrini MM; Minato N; Fagarasan S
        Current opinion in immunology, Dec. 2018, Peer-reviewed
      • Pillars Article: Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme. Cell. 2000. 102: 553-563.
        Muramatsu M; Kinoshita K; Fagarasan S; Yamada S; Shinkai Y; Honjo T
        Journal of immunology (Baltimore, Md. : 1950), Nov. 2018, Peer-reviewed
      • IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria.
        Akira Nakajima; Alexis Vogelzang; Mikako Maruya; Michio Miyajima; Megumi Murata; Aoi Son; Tomomi Kuwahara; Tatsuaki Tsuruyama; Satoshi Yamada; Minoru Matsuura; Hiroshi Nakase; Daniel A Peterson; Sidonia Fagarasan; Keiichiro Suzuki
        The Journal of experimental medicine, 06 Aug. 2018, Peer-reviewed
      • A Hen in the Wolf Den: A Pathobiont Tale
        Matteo M. Guerrini; Alexis Vogelzang; Sidonia Fagarasan
        Immunity, 17 Apr. 2018, Peer-reviewed
      • Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior
        Michio Miyajima; Baihao Zhang; Yuki Sugiura; Kazuhiro Sonomura; Matteo M. Guerrini; Yumi Tsutsui; Mikako Maruya; Alexis Vogelzang; Kenji Chamoto; Kurara Honda; Takatoshi Hikida; Satomi Ito; Hongyan Qin; Rikako Sanuki; Keiichiro Suzuki; Takahisa Furukawa; Yasushi Ishihama; Fumihiko Matsuda; Makoto Suematsu; Tasuku Honjo; Sidonia Fagarasan
        NATURE IMMUNOLOGY, Dec. 2017, Peer-reviewed
      • Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
        Kenji Chamoto; Partha S. Chowdhury; Alok Kumar; Kazuhiro Sonomura; Fumihiko Matsuda; Sidonia Fagarasan; Tasuku Honjo
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2017, Peer-reviewed
      • Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
        Baihao Zhang; Shunsuke Chikuma; Shohei Hori; Sidonia Fagarasan; Tasuku Honjo
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jul. 2016, Peer-reviewed
      • Structure and Function of IgA
        Keiichiro Suzuki; Sidonia Fagarasan
        Encyclopedia of Immunobiology, 27 Apr. 2016, Peer-reviewed
      • Fostering of advanced mutualism with gut microbiota by Immunoglobulin A
        Duncan B. Sutherland; Keiichiro Suzuki; Sidonia Fagarasan
        IMMUNOLOGICAL REVIEWS, Mar. 2016, Peer-reviewed
      • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells (vol 16, pg 276, 2015)
        Ajithkumar Vasanthakumar; Kazuyo Moro; Annie Xin; Yang Liao; Renee Gloury; Shimpei Kawamoto; Sidonia Fagarasan; Lisa A. Mielke; Shoukat Afshar-Sterle; Seth L. Masters; Susumu Nakae; Hirohisa Saito; John M. Wentworth; Peng Li; Wei Liao; Warren J. Leonard; Gordon K. Smyth; Wei Shi; Stephen L. Nutt; Shigeo Koyasu; Axel Kallies
        NATURE IMMUNOLOGY, May 2015, Peer-reviewed
      • Editorial overview: Lymphocyte development and activation: Lymphocytes, integrators of information
        Jeroen Roose; Sidonia Fagarasan
        CURRENT OPINION IN IMMUNOLOGY, Apr. 2015, Peer-reviewed
      • Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
        Laurence Macia; Jian Tan; Angelica T. Vieira; Katie Leach; Dragana Stanley; Suzanne Luong; Mikako Maruya; Craig Ian McKenzie; Atsushi Hijikata; Connie Wong; Lauren Binge; Alison N. Thorburn; Nina Chevalier; Caroline Ang; Eliana Marino; Remy Robert; Stefan Offermanns; Mauro M. Teixeira; Robert J. Moore; Richard A. Flavell; Sidonia Fagarasan; Charles R. Mackay
        NATURE COMMUNICATIONS, Apr. 2015, Peer-reviewed
      • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells
        Ajithkumar Vasanthakumar; Kazuyo Moro; Annie Xin; Yang Liao; Renee Gloury; Shimpei Kawamoto; Sidonia Fagarasan; Lisa A. Mielke; Shoukat Afshar-Sterle; Seth L. Masters; Susumu Nakae; Hirohisa Saito; John M. Wentworth; Peng Li; Wei Liao; Warren J. Leonard; Gordon K. Smyth; Wei Shi; Stephen L. Nutt; Shigeo Koyasu; Axel Kallies
        NATURE IMMUNOLOGY, Mar. 2015, Peer-reviewed
      • Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell
        Rashmi Kumar; P. Bach; Federica Mainoldi; Mikako Maruya; Satoshi Kishigami; Hassan Jumaa; Teruhiko Wakayama; Osami Kanagawa; Sidonia Fagarasan; Stefano Casola
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 2015, Peer-reviewed
      • The Mucosal Immune System: Host-Bacteria Interaction and Regulation of Immunoglobulin A Synthesis. Host-Bacteria Interaction and Regulation of Immunoglobulin A Synthesis.
        Sidonia Fagarasan; Giuliana Magri; Andrea Cerutti
        Molecular Biology of B Cells: Second Edition, 15 Dec. 2014, Peer-reviewed
      • The role of the adaptive immune system in regulation of gut microbiota
        Lucia M. Kato; Shimpei Kawamoto; Mikako Maruya; Sidonia Fagarasan
        IMMUNOLOGICAL REVIEWS, Jul. 2014, Peer-reviewed
      • Foxp3(+) T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis
        Shimpei Kawamoto; Mikako Maruya; Lucia M. Kato; Wataru Suda; Koji Atarashi; Yasuko Doi; Yumi Tsutsui; Hongyan Qin; Kenya Honda; Takaharu Okada; Masahira Hattori; Sidonia Fagarasan
        IMMUNITY, Jul. 2014, Peer-reviewed
      • Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
        Giuliana Magri; Michio Miyajima; Sabrina Bascones; Arthur Mortha; Irene Puga; Linda Cassis; Carolina M. Barra; Laura Comerma; Aleksey Chudnovskiy; Maurizio Gentile; David Llige; Montserrat Cols; Sergi Serrano; Juan Ignacio Arostegui; Manel Juan; Jordi Yaguee; Miriam Merad; Sidonia Fagarasan; Andrea Cerutti
        NATURE IMMUNOLOGY, Apr. 2014, Peer-reviewed
      • Generation of colonic IgA-secreting cells in the caecal patch
        Kazunori Masahata; Eiji Umemoto; Hisako Kayama; Manato Kotani; Shota Nakamura; Takashi Kurakawa; Junichi Kikuta; Kazuyoshi Gotoh; Daisuke Motooka; Shintaro Sato; Tomonori Higuchi; Yoshihiro Baba; Tomohiro Kurosaki; Makoto Kinoshita; Yosuke Shimada; Taishi Kimura; Ryu Okumura; Akira Takeda; Masaru Tajima; Osamu Yoshie; Masahiro Fukuzawa; Hiroshi Kiyono; Sidonia Fagarasan; Tetsuya Iida; Masaru Ishii; Kiyoshi Takeda
        NATURE COMMUNICATIONS, Apr. 2014, Peer-reviewed
      • Gut Reactions: Eosinophils Add another String to Their Bow
        Duncan B. Sutherland; Sidonia Fagarasan
        IMMUNITY, Apr. 2014, Peer-reviewed
      • Gut T-FH and IgA: key players for regulation of bacterial communities and immune homeostasis
        Lucia M. Kato; Shimpei Kawamoto; Mikako Maruya; Sidonia Fagarasan
        IMMUNOLOGY AND CELL BIOLOGY, Jan. 2014, Peer-reviewed
      • New territory for T follicular helper cells
        Carola G. Vinuesa; Sidonia Fagarasan; Chen Dong
        Immunity, 19 Sep. 2013, Peer-reviewed
      • Nuclear transferred embryonic stem cells for analysis of B1 B-lymphocyte development
        Mitsuyo Takase; Ryuji Iida; Mikako Maruya; Asako Sakaue-Sawano; Atsushi Miyawaki; Teruhiko Wakayama; Satoshi Nishigami; Sidonia Fagarasan; Osami Kanagawa
        INTERNATIONAL IMMUNOLOGY, Mar. 2013, Peer-reviewed
      • Impaired selection of IgA and intestinal dysbiosis associated with PD-1-deficiency
        Mikako Maruya; Shimpei Kawamoto; Lucia M. Kato; Sidonia Fagarasan
        Gut Microbes, Mar. 2013, Peer-reviewed
      • IgA synthesis: a form of functional immune adaptation extending beyond gut
        Duncan B. Sutherland; Sidonia Fagarasan
        CURRENT OPINION IN IMMUNOLOGY, Jun. 2012, Peer-reviewed
      • The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut
        Shimpei Kawamoto; Thinh H. Tran; Mikako Maruya; Keiichiro Suzuki; Yasuko Doi; Yumi Tsutsui; Lucia M. Kato; Sidonia Fagarasan
        SCIENCE, Apr. 2012, Peer-reviewed
      • Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease
        Jeffrey VanValkenburgh; Diana I. Albu; Chandra Bapanpally; Sarah Casanova; Danielle Califano; David M. Jones; Leszek Ignatowicz; Shimpei Kawamoto; Sidonia Fagarasan; Nancy A. Jenkins; Neal G. Copeland; Pentao Liu; Dorina Avram
        JOURNAL OF EXPERIMENTAL MEDICINE, Sep. 2011, Peer-reviewed
      • Foxp3(+) follicular regulatory T cells control the germinal center response
        Michelle A. Linterman; Wim Pierson; Sau K. Lee; Axel Kallies; Shimpei Kawamoto; Tim F. Rayner; Monika Srivastava; Devina P. Divekar; Laura Beaton; Jennifer J. Hogan; Sidonia Fagarasan; Adrian Liston; Kenneth G. C. Smith; Carola G. Vinuesa
        NATURE MEDICINE, Aug. 2011, Peer-reviewed
      • B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
        Sau K. Lee; Robert J. Rigby; Dimitra Zotos; Louis M. Tsai; Shimpei Kawamoto; Jennifer L. Marshall; Roybel R. Ramiscal; Tyani D. Chan; Dominique Gatto; Robert Brink; Di Yu; Sidonia Fagarasan; David M. Tarlinton; Adam F. Cunningham; Carola G. Vinuesa
        JOURNAL OF EXPERIMENTAL MEDICINE, Jul. 2011, Peer-reviewed
      • Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
        Min Wei; Reiko Shinkura; Yasuko Doi; Mikako Maruya; Sidonia Fagarasan; Tasuku Honjo
        NATURE IMMUNOLOGY, Mar. 2011, Peer-reviewed
      • PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
        Taku Okazaki; Il-Mi Okazaki; Jian Wang; Daisuke Sugiura; Fumio Nakaki; Taku Yoshida; Yu Kato; Sidonia Fagarasan; Masamichi Muramatsu; Tomoo Eto; Kyoji Hioki; Tasuku Honjo
        JOURNAL OF EXPERIMENTAL MEDICINE, Feb. 2011, Peer-reviewed
      • Vitamin A-dependent transcriptional activation of the nuclear factor of activated T cells c1 (NFATc1) is critical for the development and survival of B1 cells
        Mikako Maruya; Keiichiro Suzuki; Hanae Fujimoto; Michio Miyajima; Osami Kanagawa; Teruhiko Wakayama; Sidonia Fagarasan
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2011, Peer-reviewed
      • Roles of B-1 and B-2 cells in innate and acquired IgA-mediated immunity
        Keiichiro Suzuki; Mikako Maruya; Shimpei Kawamoto; Sidonia Fagarasan
        IMMUNOLOGICAL REVIEWS, Sep. 2010, Peer-reviewed
      • The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut
        Keiichiro Suzuki; Mikako Maruya; Shimpei Kawamoto; Katarzyna Sitnik; Hiroshi Kitamura; William W. Agace; Sidonia Fagarasan
        IMMUNITY, Jul. 2010, Peer-reviewed
      • B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
        Thinh Huy Tran; Mikiyo Nakata; Keiichiro Suzuki; Nasim A. Begum; Reiko Shinkura; Sidonia Fagarasan; Tasuku Honjo; Hitoshi Nagaoka
        Nature Immunology, Feb. 2010, Peer-reviewed
      • B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
        Thinh Huy Tran; Mikiyo Nakata; Keiichiro Suzuki; Nasim A. Begum; Reiko Shinkura; Sidonia Fagarasan; Tasuku Honjo; Hitoshi Nagaoka
        NATURE IMMUNOLOGY, Feb. 2010, Peer-reviewed
      • Adaptive Immune Regulation in the Gut: T Cell-Dependent and T Cell-Independent IgA Synthesis
        Sidonia Fagarasan; Shimpei Kawamoto; Osami Kanagawa; Keiichiro Suzuki
        ANNUAL REVIEW OF IMMUNOLOGY, VOL 28, 2010, Peer-reviewed
      • Advances in Immunology. Mucosal immunity. Preface.
        Fagarasan S; Cerutti A
        Advances in immunology, 2010, Peer-reviewed
      • GALT: Organization and Dynamics Leading to IgA Synthesis
        Keiichiro Suzuki; Shimpei Kawamoto; Mikako Maruya; Sidonia Fagarasan
        MUCOSAL IMMUNITY, 2010, Peer-reviewed
      • Preferential Generation of Follicular B Helper T Cells from Foxp3(+) T Cells in Gut Peyer's Patches
        Masayuki Tsuji; Noriko Komatsu; Shimpei Kawamoto; Keiichiro Suzuki; Osami Kanagawa; Tasuku Honjo; Shohei Hori; Sidonia Fagarasan
        SCIENCE, Mar. 2009, Peer-reviewed
      • Diverse regulatory pathways for IgA synthesis in the gut
        K. Suzuki; S. Fagarasan
        Mucosal Immunology, 2009, Peer-reviewed
      • How host-bacterial interactions lead to IgA synthesis in the gut
        Keiichiro Suzuki; Sidonia Fagarasan
        TRENDS IN IMMUNOLOGY, Nov. 2008, Peer-reviewed
      • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin a generation in the gut
        Masayuki Tsuji; Keiichiro Suzuki; Hiroshi Kitamura; Mikako Maruya; Kazuo Kinoshita; Ivaylo I. Ivanov; Kikuji Itoh; Dan R. Littman; Sidonia Fagarasan
        IMMUNITY, Aug. 2008, Peer-reviewed
      • Evolution, development, mechanism and function of IgA in the gut
        Sidonia Fagarasan
        CURRENT OPINION IN IMMUNOLOGY, Apr. 2008, Peer-reviewed
      • Dynamic interactions between bacteria and immune cells leading to intestinal IgA synthesis
        Masayuki Tsuji; Keiichiro Suzuki; Kazuo Kinoshita; Sidonia Fagarasan
        SEMINARS IN IMMUNOLOGY, Feb. 2008, Peer-reviewed
      • Intestinal IgA synthesis: A primitive form of adaptive immunity that regulates microbial communities in the gut
        Keiichiro Suzuki; Seon-ah Ha; Masayuki Tsuji; Sidonia Fagarasan
        SEMINARS IN IMMUNOLOGY, Apr. 2007, Peer-reviewed
      • Regulation of B1 cell migration by signals through Toll-like receptors
        Seon-ah Ha; Masayuki Tsuji; Keiichiro Suzuki; Bob Meek; Nobutaka Yasuda; Tsuneyasu Kaisho; Sidonia Fagarasan
        JOURNAL OF EXPERIMENTAL MEDICINE, Oct. 2006, Peer-reviewed
      • Two distinctive pathways for recruitment of naive and primed IgM(+) B cells to the gut lamina propria
        K Suzuki; B Meek; Y Doi; T Honjo; S Fagarasan
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 2005, Peer-reviewed
      • Regulation of IgA synthesis at mucosal surfaces
        S Fagarasan; T Honjo
        CURRENT OPINION IN IMMUNOLOGY, Jun. 2004, Peer-reviewed
      • AID: How does it aid antibody diversity?
        T Honjo; M Muramatsu; S Fagarasan
        IMMUNITY, Jun. 2004, Peer-reviewed
      • Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
        K Suzuki; B Meek; Y Doi; M Muramatsu; T Chiba; T Honjo; S Fagarasan
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 2004, Peer-reviewed
      • Intestinal IgA synthesis: Regulation of front-line body defences
        S Fagarasan; T Honjo
        NATURE REVIEWS IMMUNOLOGY, Jan. 2003, Peer-reviewed
      • Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora
        S Fagarasan; M Muramatsu; K Suzuki; H Nagaoka; H Hiai; T Honjo
        SCIENCE, Nov. 2002, Peer-reviewed
      • 外来AID強制発現によるAID欠損B細胞のクラススイッチ能の回復
        村松 正道; 木下 和生; 鄭 一美; シドニア・ファガラサン; 本庶 佑
        日本免疫学会総会・学術集会記録, Dec. 2001
      • 新たなクラススイッチ組換えの指標 環状DNAに由来する転写産物の検出
        木下 和生; 張谷 素子; シドニア・ファガラサン; 村松 正道; 本庶 佑
        日本免疫学会総会・学術集会記録, Dec. 2001
      • In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
        S. Fagarasan; K. Kinoshita; M. Muramatsu; K. Ikuta; T. Honjo
        Nature, 11 Oct. 2001, Peer-reviewed
      • A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
        K Kinoshita; M Harigai; S Fagarasan; M Muramatsu; T Honjo
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2001, Peer-reviewed
      • 新たなクラススイッチ組換えの指標 環状DNAに由来する転写産物の検出
        木下 和生; 張谷 素子; Fagarasan Sidonia; 村松 正道; 本庶 佑
        生化学, Aug. 2001
      • Migration and differentiation of autoreactive B-1 cells induced by activated gamma/delta T cells in antierythrocyte immunoglobulin transgenic mice
        N Watanabe; K Ikuta; S Fagarasan; S Yazumi; T Chiba; T Honjo
        JOURNAL OF EXPERIMENTAL MEDICINE, Dec. 2000, Peer-reviewed
      • クラススイッチ組み換えと体細胞超変異にはRNA校正cytidine deaminaseファミリーの一つである活性化誘導cytidine deaminase(AID)を必要とする
        村松 正道; 木下 和生; Fagarasan Sidonia; 山田 秀一; 真貝 洋一; 本庶 佑
        生化学, Aug. 2000
      • Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA, (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA
        T Kamata; F Nogaki; S Fagarasan; T Sakiyama; N Kobayashi; S Miyawaki; K Ikuta; E Muso; H Yoshida; S Sasayama; T Honjo
        JOURNAL OF IMMUNOLOGY, Aug. 2000, Peer-reviewed
      • Alymphoplasia (aly)-type nuclear factor κB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system
        Sidonia Fagarasan; Reiko Shinkura; Tadashi Kamata; Fumiaki Nogaki; Koichi Ikuta; Kei Tashiro; Tasuku Honjo
        Journal of Experimental Medicine, 01 May 2000, Peer-reviewed
      • Mechanism of B1 cell differentiation and migration in GALT
        S. Fagarasan; R. Shinkura; T. Kamata; F. Nogaki; K. Ikuta; T. Honjo
        Current Topics in Microbiology and Immunology, 2000, Peer-reviewed

      Misc.

      • The effects of immune activation on emotional behaviors
        Michio Miyajima; Sidonia Fagarasan
        Medical Science Digest, Dec. 2019
      • PD-1欠損マウスにおけるT細胞の活性化に起因する全身性のメタボロームのシフトを介した情動行動の変化
        宮島 倫生; Sidonia Fagarasan
        感染・炎症・免疫, Apr. 2019
      • 免疫と脳
        宮島 倫生; Sidonia Fagarasan
        生体の科学, Apr. 2019
      • T細胞活性化に起因する全身性のメタボロームシフトを介した情動行動変化
        宮島倫生; 章白浩; 章白浩; 杉浦悠毅; 園村和弘; グェッリーニ マッテオ; 茶本健司; 古川貴久; 石濱泰; 松田文彦; 末松誠; 本庶佑; ファガラサン シドニア
        がんと代謝研究会プログラム&抄録集, 2019
      • 腸内細菌叢や免疫系が情動に及ぼす影響
        宮島 倫生; Sidonia Fagarasan
        実験医学, 2019
      • Relationship between immune activation and enhanced anxiety and fear
        宮島 倫生; Fagarasan Sidonia
        臨床免疫・アレルギー科 = Clinical immunology & allergology, Jun. 2018
      • PD-1欠損マウスにおける全身性のT細胞の活性化に起因するメタボロームのシフトを介した情動行動の変化
        宮島 倫生; Sidonia Fagarasan
        新着論文レビュー, 2017
      • Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.
        Zhang Baihao; Chikuma Shunsuke; Hori Shohei; Fagarasan Sidonia; Honjo Tasuku
        Proceedings of the National Academy of Sciences of the United States of America, 07 Jul. 2016
      • The regulation of gut microbiota by T follicular helper cells and IgA
        河本 新平; Sidonia Fagarasan
        医学のあゆみ, 02 May 2015
      • Foxp3⁺ T細胞による抗原特異的なIgAを介した腸内細菌制御 (特集 宿主と共生細菌の間の相互作用による免疫学的恒常性)
        河本 新平; Fagarasan Sidonia
        臨床免疫・アレルギー科, Apr. 2015
      • The IgA Receptor in B Cell Homeostasis: Lessons from IgA Transnuclear Mice
        Rashmi Kumar; Martina Bach; Hassan Jumaa; Teruhiko Wakayama; Osami Kanagawa; Sidonia Fagarasan; Stefano Casola
        SCANDINAVIAN JOURNAL OF IMMUNOLOGY, Sep. 2014
      • 自然リンパ球は間質細胞および免疫細胞からのシグナルを統合することにより辺縁帯B細胞からの抗体の産生を増強する
        宮島倫生; Sidonia Fagarasan
        新着論文レビュー, 2014
      • W2-2 Foxp3+ T細胞,IgA及び腸内細菌叢の間に見られる相互制御ループの解明
        河本 新平; 服部 正平; FAGARASAN Sidonia; 丸谷 美香子; 加藤 ルシア; 須田 亙; 新 幸二; 土井 靖子; 筒井 裕美; 本田 賢也; 岡田 峰陽
        日本臨床免疫学会会誌, 2014
      • A rheostat for immune responses: The unique properties of PD-1 and their advantages for clinical application
        Taku Okazaki; Shunsuke Chikuma; Yoshiko Iwai; Sidonia Fagarasan; Tasuku Honjo
        Nature Immunology, Dec. 2013
      • Foxp3(+) follicular regulatory T cells control the germinal centre response
        M. A. Linterman; W. Pierson; S. K. Lee; A. Kallies; S. Kawamoto; S. Fagarasan; A. Liston; C. G. Vinuesa; K. G. C. Smith
        IMMUNOLOGY, Sep. 2012
      • Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal centre response
        M. A. Linterman; W. Pierson; S. K. Lee; A. Kallies; S. Kawamoto; T. F. Rayner; M. Srivastava; D. P. Divekar; L. Beaton; J. J. Hogan; S. Fagarasan; A. Liston; C. G. Vinuesa; K. C. G. Smith
        IMMUNOLOGY, Jun. 2012
      • Foxp3(+) follicular regulatory T cells control T follicular helper cells and the germinal centre response
        M. Linterman; W. Pierson; C. Lee; A. Kallies; T. Rayner; S. Kawamoto; S. Fagarasan; A. Liston; K. G. C. Smith; C. Vinuesa
        IMMUNOLOGY, Dec. 2011
      • Activation-Induced Cytidine Deaminase Expression in CD4(+) T Cells is Associated with a Unique IL-10-Producing Subset that Increases with Age
        Hongyan Qin; Keiichiro Suzuki; Mikiyo Nakata; Shunsuke Chikuma; Nakako Izumi; Le Thi Huong; Mikako Maruya; Sidonia Fagarasan; Meinrad Busslinger; Tasuku Honjo; Hitoshi Nagaoka
        PLOS ONE, Dec. 2011
      • S8-5 Regulation of IgA synthesis in gut(S8 Tfh and GC formation)
        Fagarasan Sidonia
        Japanese Journal of Allergology, 2011
      • B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
        Honjo Tasuku; Nagaoka Hitoshi; Tran Thinh Huy; Nakata Mikiyo; Suzuki Keiichiro; Begum Nasim A; Shinkura Reiko; Fagarasan Sidonia
        Nature Immunology, 06 Dec. 2009
      • 成体の腸におけるRORgt陽性LTi細胞の役割(The roles of RORgt+ LTi cells in adult gut)
        辻 正幸; 鈴木 敬一朗; 北村 浩; 小原 收; 伊藤 喜久治; Fagarasan Sidonia
        日本免疫学会総会・学術集会記録, Oct. 2007
      • The Mechanism of Immune Maturation Mediated by Gut Flora
        SUZUKI Keiichiro; TSUJI Masayuki; YAGISAWA Akiko; MARUYA Mikako; SATO Ayuko; MEEK Bob; FAGARASAN Sidonia
        腸内細菌学雑誌 = Journal of intestinal microbiology, 01 Apr. 2007
      • Intestinal IgA synthesis: A primitive form of adaptive immunity that regulates microbial communities in the gut
        S. Fagarasan
        GUT-ASSOCIATED LYMPHOID TISSUES, 2006
      • 腸管免疫系と腸内細菌叢のクロストーク (免疫2004) -- (獲得免疫)
        鈴木 敬一朗; 村松 正道; Fagarasan Sidonia
        免疫, 2004
      • T-independent immune response: New aspects of B cell biology
        S Fagarasan; T Honjo
        SCIENCE, Oct. 2000
      • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
        M Muramatsu; K Kinoshita; S Fagarasan; S Yamada; Y Shinkai; T Honjo
        CELL, Sep. 2000
      • Generation, expansion, migration and activation of mouse B1 cells
        S Fagarasan; N Watanabe; T Honjo
        IMMUNOLOGICAL REVIEWS, Aug. 2000
      list
        Last Updated :2022/05/14

        Administration

        Faculty management (title, position)

        • From 01 Apr. 2021
          柳井基金運営委員会委員
        • From 01 Aug. 2020, To 31 Dec. 2020
          がん免疫総合研究センター運営委員会委員

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