Basic Information

Professional Memberships

• International Association for the Sensitization of Cancer Treatment
• Japanese Cancer Association
• Japan Society of Clinical Oncology
• Japan Society for Head and Neck Cancer
• Japanese Society for Radiation Oncology
• Japan Radiological Society

Academic Degree

• PhD, Medicine(Kyoto University)

Academic Resume (Graduate Schools)

• Kyoto University, Graduate School of Medicine, Radiation Oncology, 研究指導認定退学
• Kyoto University, Graduate School of Medicine, Radiation Oncology, 修了

Academic Resume (Undergraduate School/Majors)

• Kyoto University, Faculty of Medicine, 卒業

High School

• High School

  洛南高等学校

Language of Instruction

• Japanese
• English

ID,URL

• ORCID ID

  0000-0001-5412-5843

• J-Global ID

  202101014884093583

• Researcher number

  90802778

researchmap URL

• https://researchmap.jp/NakashimaR

Research

Research Topics, Overview of the research

• Research Topics

  NETs（Neutrophil Extracellular Traps）によるがん遠隔転移メカニズムの解明および新規治療法の開発、放射線治療抵抗性因子の同定および新規治療法の開発

• Overview of the research

  NETs（Neutrophil Extracellular Traps）によるがん遠隔転移メカニズムの解明および新規治療法の開発、放射線治療抵抗性因子の同定および新規治療法の開発

Papers

• Integration test of biaxially rotational dynamic-radiation therapy for nasopharyngeal carcinoma: Efficacy evaluation and dosimetric analysis

  Shinya Hiraoka; Hideaki Hirashima; Mitsuhiro Nakamura; Fumiya Tanaka; Hiroki Adachi; Yuka Ono; Tomohiro Ono; Ryota Nakashima; Aya Nakajima; Takashi Mizowaki

  Radiotherapy and Oncology, Apr. 2025

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• Postoperative hyperfractionated IMRT with weekly cisplatin for head and neck cancer: phase IIa trial

  Shinya Hiraoka; Aya Nakajima; Masahiro Kikuchi; Motoo Nomura; Toshiyuki Imagumbai; Michio Yoshimura; Ryota Nakashima; Yo Kishimoto; Shogo Shinohara; Masaki Kokubo; Koichi Omori; Takashi Mizowaki

  Journal of Radiation Research, 05 Mar. 2025

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• 332 Radiotherapy with or without weekly cisplatin for elderly patients with head and neck cancer

  Yumi Kokubo; Shinya Hiraoka; Yo Kishimoto; Shogo Shinohara; Ryota Nakashima; Aya Nakajima; Michio Yoshimura; Chiaki Suzuki; Keigo Honda; Peter J.K. Tokuda; Ryo Ashida; Takamasa Mitsuyoshi; Toshiyuki Imagumbai; Tetsuhiko Michida; Masahiro Kikuchi; Masaki Kokubo; Koichi Omori; Takashi Mizowaki

  Radiotherapy and Oncology, Aug. 2024

  
• Preserving Laryngo‐Esophageal Function in Patients With Hypopharyngeal Cancer Treated With Radiotherapy: Predictive Factors and Long‐Term Outcomes

  Aya Nakajima; Michio Yoshimura; Shinya Hiraoka; Ryota Nakashima; Yo Kishimoto; Koichi Omori; Takashi Mizowaki

  Cancer Medicine, 02 Nov. 2024

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• Long-term outcomes of stimulated salivary flow and xerostomia after definitive intensity-modulated radiation therapy for patients with head and neck cancer†.

  Shinya Hiraoka; Michio Yoshimura; Aya Nakajima; Ryota Nakashima; Takashi Mizowaki

  Journal of radiation research, 19 Jan. 2024

  
• Long-term survival outcomes and recurrence patterns of olfactory neuroblastoma: A 13-year experience at a single institution

  Masahiro Kikuchi; Takayuki Nakagawa; Yuji Kitada; Mami Matsunaga; Masahiro Tanji; Shinya Hiraoka; Ryota Nakashima; Aya Nakajima; Michio Yoshimura; Koichi Omori

  Auris Nasus Larynx, Dec. 2022

  
• Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation.

  Jiro Ikeda; Corey A Scipione; Sharon J Hyduk; Marwan G Althagafi; Jawairia Atif; Sarah A Dick; Maneesha Rajora; Erika Jang; Takuo Emoto; Junichi Murakami; Noriko Ikeda; Hisham M Ibrahim; Chanele K Polenz; Xiaotang Gao; Kelly Tai; Jenny Jongstra-Bilen; Ryota Nakashima; Slava Epelman; Clinton S Robbins; Gang Zheng; Warren L Lee; Sonya A MacParland; Myron I Cybulsky

  Circulation research, 19 Feb. 2021

  
• Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis.

  Minoru Inoue; Ryota Nakashima; Masahiro Enomoto; Yuhki Koike; Xiao Zhao; Kenneth Yip; Shao Hui Huang; John N Waldron; Mitsuhiko Ikura; Fei-Fei Liu; Scott V Bratman

  Nature communications, 30 Nov. 2018

  
• UCHL1-HIF-1経路による抗酸化作用は放射線治療効果の増強に資する標的となり得る

  中島 良太; 後藤 容子; 子安 翔; 小林 稔; 吉村 通央; 平岡 眞寛; 原田 浩

  日本癌学会総会記事, Sep. 2017

  
• UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.

  Ryota Nakashima; Yoko Goto; Sho Koyasu; Minoru Kobayashi; Akiyo Morinibu; Michio Yoshimura; Masahiro Hiraoka; Ester M Hammond; Hiroshi Harada

  Scientific reports, 31 Jul. 2017

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Misc.

• UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

  Ryota Nakashima; Yoko Goto; Sho Koyasu; Minoru Kobayashi; Michio Yoshimura; Masahiro Hiraoka; Hiroshi Harada

  CANCER SCIENCE, Jan. 2018

  

External funds: Kakenhi

• UCHL1-HIF-1経路による放射線治療抵抗性の分子メカニズムの解明と対策

  Grant-in-Aid for Research Activity Start-up

  Kyoto University

  中島 良太

  From 25 Aug. 2017, To 31 Mar. 2019, Declined

  放射線治療抵抗性;代謝リプログラミング;グルタチオン;放射線腫瘍学;放射線増感;低酸素

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H06812/
• 放射線治療による好中球細胞外トラップを介した遠隔転移のメカニズム解明と予防法開発

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  中島 良太

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  好中球細胞外トラップス;NETs;遠隔転移;放射線治療;好中球細胞外トラップ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K15864/
• Elucidation of the mechanisms of cancer malignancy mediated by citrullinating enzyme PAD4 and development of novel PAD4-targeted therapeutic strategies

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  中島 良太

  From 01 Apr. 2025, To 31 Mar. 2028, Granted

  PAD4;シトルリン化;がん;放射線増感;エピジェネティック

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25K19166/