Basic Information

Email Address

• Email Address

  ikeda.yoshiki.3rkyoto-u.ac.jp

Academic Degree

• 28 Feb. 2011

  名古屋大学博士（理学）
• 27 Mar. 2008

  名古屋大学修士（理学）

Research History

• From Dec. 2024, To Present

  Kyoto University, 成長戦略本部
• From Dec. 2024, To Present

  Kyoto University, Graduate School of Medicine, KUMBL

ID,URL

• J-Global ID

  201801002171353204

researchmap URL

• https://researchmap.jp/yoshikiikeda

Research

Research Areas

• Life sciences, Pharmaceuticals - chemistry and drug development

Papers

• Structural insights into CDF1 accumulation on the CONSTANS promoter via a plant-specific DNA-binding domain

  Hirotake Furihata; Zhangliang Zhu; Kaisei Nishida; Yasuhito Sakuraba; Akihiro Tsuji; Hayato Yamashita; Shohei Nosaki; Ryo Tachibana; Ayumi Yamagami; Yoshiki Ikeda; Masayuki Abe; Tatsuya Sawasaki; Takeshi Nakano; Shuichi Yanagisawa; Masaru Tanokura; Takuya Miyakawa

  Nature Plants, 22 Apr. 2025

  
• PI5P4K inhibitors: promising opportunities and challenges

  Koh Takeuchi; Lisa Nagase; Shun Kageyama; Hirotaka Kanoh; Masashi Oshima; Aki Ogawa‐Iio; Yoshiki Ikeda; Yuki Fujii; Sei Kondo; Natsuki Osaka; Takeshi Masuda; Tsukasa Ishihara; Yoshikazu Nakamura; Yoshihisa Hirota; Takehiko Sasaki; Toshiya Senda; Atsuo T. Sasaki

  The FEBS Journal, 19 Jan. 2025, Peer-reviewed

  
• Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1

  Tatsuhiko Ozawa; Yoshiki Ikeda; Liuan Chen; Rigel Suzuki; Atsushi Hoshino; Akira Noguchi; Shunsuke Kita; Yuki Anraku; Emiko Igarashi; Yumiko Saga; Noriko Inasaki; Shunta Taminishi; Jiei Sasaki; Yuhei Kirita; Hideo Fukuhara; Katsumi Maenaka; Takao Hashiguchi; Takasuke Fukuhara; Kenichi Hirabayashi; Hideki Tani; Hiroyuki Kishi; Hideki Niimi

  Structure, 15 Jan. 2024, Peer-reviewed, Lead author, Corresponding author

  
• がんの接着による制御機構の解明と創薬

  植田 祥啓; 岩田 亮一; 山崎 文和; 赤間 智也; 三木 貴雄; 住吉 麻実; 平野 伸二; 福原 貴太郎; 上岡 裕治; 近藤 直幸; 池田 幸樹

  関西医科大学雑誌, Dec. 2020

  
• Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.

  Yoshiki Ikeda; Mindy I Davis; Kazutaka Sumita; Yuxiang Zheng; Satoshi Kofuji; Mika Sasaki; Yoshihisa Hirota; Rajan Pragani; Min Shen; Matthew B Boxer; Koh Takeuchi; Toshiya Senda; Anton Simeonov; Atsuo T Sasaki

  Biochemical and biophysical research communications, 26 Aug. 2023, Peer-reviewed, Lead author

  Access this paper :

  
• Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1.

  Yoshihiro Ueda; Koichiro Higasa; Yuji Kamioka; Naoyuki Kondo; Shunsuke Horitani; Yoshiki Ikeda; Wolfgang Bergmeier; Yoshinori Fukui; Tatsuo Kinashi

  iScience, 18 Aug. 2023

  
• Characterization of cytoskeletal and structural effects of INF2 variants causing glomerulopathy and neuropathy.

  Hiroko Ueda; Quynh Thuy Huong Tran; Linh Nguyen Truc Tran; Koichiro Higasa; Yoshiki Ikeda; Naoyuki Kondo; Masaki Hashiyada; Chika Sato; Yoshinori Sato; Akira Ashida; Saori Nishio; Yasunori Iwata; Hiroyuki Iida; Daisuke Matsuoka; Yoshihiko Hidaka; Kenji Fukui; Suzu Itami; Norihito Kawashita; Keisuke Sugimoto; Kandai Nozu; Motoshi Hattori; Hiroyasu Tsukaguchi

  Scientific reports, 25 Jul. 2023

  
• The critical role of Rap1-GAPs Rasa3 and Sipa1 in T cells for pulmonary transit and egress from the lymph nodes.

  Shunsuke Horitani; Yoshihiro Ueda; Yuji Kamioka; Naoyuki Kondo; Yoshiki Ikeda; Makoto Naganuma; Tatsuo Kinashi

  Frontiers in immunology, 2023

  
• Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

  Yuji Kamioka; Yoshihiro Ueda; Naoyuki Kondo; Keizo Tokuhiro; Yoshiki Ikeda; Wolfgang Bergmeier; Tatsuo Kinashi

  Cell Reports, Jun. 2023

  
• Functional molecular evolution of a GTP sensing kinase: PI5P4Kβ.

  Koh Takeuchi; Miki Senda; Yoshiki Ikeda; Koji Okuwaki; Kaori Fukuzawa; So Nakagawa; Mika Sasaki; Atsuo T Sasaki; Toshiya Senda

  The FEBS journal, 01 Mar. 2023

  
• The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity.

  Koh Takeuchi; Yoshiki Ikeda; Miki Senda; Ayaka Harada; Koji Okuwaki; Kaori Fukuzawa; So Nakagawa; Hong Yang Yu; Lisa Nagase; Misaki Imai; Mika Sasaki; Yu-Hua Lo; Doshun Ito; Natsuki Osaka; Yuki Fujii; Atsuo T Sasaki; Toshiya Senda

  Structure (London, England : 1993), 02 Jun. 2022, Peer-reviewed, Lead author

  
• SI-MOIRAI: A new method to identify and quantify the metabolic fate of nucleotides

  Yoshiki Ikeda; Akiyoshi Hirayama; Satoshi Kofuji; Yoshihisa Hirota; Ryo Kamata; Natsuki Osaka; Yuki Fujii; Mika Sasaki; Satsuki Ikeda; Eric P Smith; Robert Bachoo; Tomoyoshi Soga; Atsuo T Sasaki

  The Journal of Biochemistry, 09 Jul. 2021, Peer-reviewed, Lead author

  
• Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification

  Natsuki Osaka; Yoshihisa Hirota; Doshun Ito; Yoshiki Ikeda; Ryo Kamata; Yuki Fujii; Venkat R. Chirasani; Sharon L. Campbell; Koh Takeuchi; Toshiya Senda; Atsuo T. Sasaki

  Frontiers in Molecular Biosciences, 08 Jul. 2021, Peer-reviewed

  
• Effect of Learning Dataset for Identification of Active Molecules: A Case Study of Integrin αIIbβ3 Inhibitors.

  Kentaro Kawai; Mami Tomonou; Yume Machida; Yukiko Karuo; Atsushi Tarui; Kazuyuki Sato; Yoshiki Ikeda; Tatsuo Kinashi; Masaaki Omote

  Molecular informatics, 18 Mar. 2021, Peer-reviewed

  
• Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer’s disease

  Masanori A. Murayama; Nagisa Arimitsu; Jun Shimizu; Naruyoshi Fujiwara; Kenji Takai; Yoshiki Ikeda; Yoko Okada; Chieko Hirotsu; Erika Takada; Tomoko Suzuki; Noboru Suzuki

  Experimental Animals, 2021, Peer-reviewed

  
• Activity-specificity trade-off gives PI5P4Kβ a nucleotide preference to function as a GTP-sensing kinase

  Koh Takeuchi; Yoshiki Ikeda; Miki Senda; Ayaka Harada; Koji Okuwaki; Kaori Fukuzawa; So Nakagawa; Hongyang Yu; Lisa Nagase; Misaki Imai; Mika Sasaki; YuHua Lo; Atsuo T. Sasaki; Toshiya Senda

  bioRxiv, 10 Jun. 2020

  
• IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.

  Satoshi Kofuji; Akiyoshi Hirayama; Alexander Otto Eberhardt; Risa Kawaguchi; Yuki Sugiura; Oltea Sampetrean; Yoshiki Ikeda; Mikako Warren; Naoya Sakamoto; Shuji Kitahara; Hirofumi Yoshino; Daisuke Yamashita; Kazutaka Sumita; Kara Wolfe; Lisa Lange; Satsuki Ikeda; Hiroko Shimada; Noriaki Minami; Akshiv Malhotra; Shin Morioka; Yuki Ban; Maya Asano; Victoria L Flanary; Annmarie Ramkissoon; Lionel M L Chow; Juri Kiyokawa; Tomoyuki Mashimo; Greg Lucey; Sergey Mareninov; Tatsuya Ozawa; Nobuyuki Onishi; Koichi Okumura; Jumpei Terakawa; Takiko Daikoku; Trisha Wise-Draper; Nazanin Majd; Kaori Kofuji; Mika Sasaki; Masaru Mori; Yonehiro Kanemura; Eric P Smith; Dimitrios Anastasiou; Hiroaki Wakimoto; Eric C Holland; William H Yong; Craig Horbinski; Ichiro Nakano; Ralph J DeBerardinis; Robert M Bachoo; Paul S Mischel; Wataru Yasui; Makoto Suematsu; Hideyuki Saya; Tomoyoshi Soga; Ingrid Grummt; Holger Bierhoff; Atsuo T Sasaki

  Nature cell biology, Aug. 2019, Peer-reviewed

  
• Identification of lysine methylation in the core GTPase domain by GoMADScan.

  Yoshino H; Yin G; Kawaguchi R; Popov KI; Temple B; Sasaki M; Kofuji S; Wolfe K; Kofuji K; Okumura K; Randhawa J; Malhotra A; Majd N; Ikeda Y; Shimada H; Kahoud ER; Haviv S; Iwase S; Asara JM; Campbell SL; Sasaki AT

  PloS one, 2019, Peer-reviewed

  
• 多角的解析からみえてくるGTPの新たな機能と人疾患への治療戦略 時系列マルチオミクス解析によるGTP代謝とがん化をつなぐ制御メカニズムの解明

  河口 理紗; デホーン・ミヒル; 池田 幸樹; 小藤 智史; 平山 明由; 森 大; 曽我 朋義; 竹内 恒; 千田 俊哉; 佐々木 敦朗; 木立 尚孝

  生命科学系学会合同年次大会, Dec. 2017

  
• An archaeal RNA binding protein, FAU-1, is a novel ribonuclease related to rRNA stability in Pyrococcus and Thermococcus

  Yoshiki Ikeda; Yasuhiro Okada; Asako Sato; Tamotsu Kanai; Masaru Tomita; Haruyuki Atomi; Akio Kanai

  SCIENTIFIC REPORTS, Oct. 2017, Peer-reviewed

  Access this paper :

  
• 【がん代謝 ワールブルグを超えて全容解明に挑む トリガーとなる分子、腸内細菌や免疫細胞の関与、標的治療の展望】(第2章)がん特異的な代謝 GTP代謝

  小藤 智史; 池田 幸樹; Wolfe Kara; Randhawa Jaskirat; 河口 理紗; 島田 裕子; 小藤 香織; 佐々木 美加; 奥村 晃市; 竹内 恒; 千田 俊哉; 佐々木 敦朗

  実験医学, Jun. 2017

  
• Structural reverse genetics study of the PI5P4K beta-nucleotide complexes reveals the presence of the GTP bioenergetic system in mammalian cells

  Koh Takeuchi; Miki Senda; Yu-Hua Lo; Satoshi Kofuji; Yoshiki Ikeda; Atsuo T. Sasaki; Toshiya Senda

  FEBS JOURNAL, Oct. 2016, Peer-reviewed

  
• The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis

  Kazutaka Sumita; Yu-Hua Lo; Koh Takeuchi; Miki Senda; Satoshi Kofuji; Yoshiki Ikeda; Jumpei Terakawa; Mika Sasaki; Hirofumi Yoshino; Nazanin Majd; Yuxiang Zheng; Emily Rose Kahoud; Takehiro Yokota; Brooke M. Emerling; John M. Asara; Tetsuo Ishida; Jason W. Locasale; Takiko Daikoku; Dimitrios Anastasiou; Toshiya Senda; Atsuo T. Sasaki

  Molecular Cell, 21 Jan. 2016, Peer-reviewed

  
• The Lipid Kinase PI5P4K beta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis

  Kazutaka Sumita; Yu-Hua Lo; Koh Takeuchi; Miki Senda; Satoshi Kofuji; Yoshiki Ikeda; Jumpei Terakawa; Mika Sasaki; Hirofumi Yoshino; Nazanin Majd; Yuxiang Zheng; Emily Rose Kahoud; Takehiro Yokota; Brooke M. Emerling; John M. Asara; Tetsuo Ishida; Jason W. Locasale; Takiko Daikoku; Dimitrios Anastasiou; Toshiya Senda; Atsuo T. Sasaki

  MOLECULAR CELL, Jan. 2016, Peer-reviewed

  
• SSK1, a novel GTP-dependent kinase, detects GTP levels and regulates tumorigenesis

  K. Sumita; K. Takeuchi; Y. Lo; M. Senda; S. Kofuji; Y. Ikeda; H. Yoshino; M. Sasaki; J. Terakawa; T. Daikoku; L. C. Cantley; T. Senda; A. T. Sasaki

  MOLECULAR BIOLOGY OF THE CELL, 2015, Peer-reviewed

  
• Hfq binding at RhlB-recognition region of RNase E is crucial for the rapid degradation of target mRNAs mediated by sRNAs in Escherichia coli

  Yoshiki Ikeda; Mieko Yagi; Teppei Morita; Hiroji Aiba

  MOLECULAR MICROBIOLOGY, Jan. 2011, Peer-reviewed

  

Misc.

• Novel method for quantification of interaction between Integrin and the binding partner

  池田幸樹; 竹田浩之; 木梨達雄

  日本分子生物学会年会プログラム・要旨集(Web), 2021

  
• Molecular evolution of PI5P4Kβ that underlies the GTP resilience

  竹内恒; 池田幸樹; 千田美紀; 原田彩佳; 奥脇弘次; 福澤薫; 中川草; 長瀬里沙; 今井美咲; 廣田佳久; 佐々木敦朗; 千田俊哉

  日本分子生物学会年会プログラム・要旨集(Web), 2021

  
• Drug discovery strategy for transmembrane proteins from the perspective of integrin drug discovery

  Yoshiki Ikeda; Tatsuo Kinashi

  SAR News, Oct. 2020, Peer-reviewed, Invited, Lead author, Corresponding author

  
• がん特異的な代謝 7.GTP代謝

  小藤智史; 小藤智史; 池田幸樹; WOLFE Kara; RANDHAWA Jaskirat; 河口理紗; 河口理紗; 島田裕子; 小藤香織; 佐々木美加; 奥村晃市; 奥村晃市; 竹内恒; 千田俊哉; 佐々木敦朗

  実験医学, 15 Jun. 2017

  
• GTP metabolic switch promotes malignant growth of brain tumors

  S. Kofuji; M. Warren; K. Sumita; A. Ramkissoon; M. Sasaki; N. Majd; H. Yoshino; K. Kofuji; K. Okumura; Y. Ikeda; R. Rao; L. Chow; A. T. Sasaki

  MOLECULAR BIOLOGY OF THE CELL, 2015

  
• ArchaeaにおけるRNA binding proteinであるFAU‐1はRibosomal RNAのprocessingに関わる新規RNaseである

  IKEDA YOSHIKI; OKADA YASUHIRO; SATO ASAKO; KANAI TAMOTSU; TOMITA MASARU; ATOMI HARUYUKI; KANAI AKIO

  日本分子生物学会年会プログラム・要旨集(Web), 2014

  

Presentations

• Development of “Miniature antibody” technology

  Yoshiki Ikeda

  GTRセミナー, 07 Jan. 2025, Invited

  
• Academic Drug Development Conference 2024

  MBSJ 2024, 27 Nov. 2024

  
• Devilish protein engineering: “Protein Carving”

  Yoshiki Ikeda

  MBSJ 2024, 27 Nov. 2024, Invited

  
• ~Feel like makin’ “Molecular Glue”~

  Yoshiki Ikeda

  第35回高遠シンポジウム, 26 Aug. 2024

  
• 弱い相互作用を定量・可視化する”Hakoniwa(箱庭)”テクノロジー

  池田 幸樹

  Seeds-Hub フォーラム, 09 Jul. 2024, Invited

  
• Feel Like Makin’ the Drug ~ Create Miniature Antibodies ~

  Yoshiki Ikeda

  2024 iCeMS retreat, 05 Jul. 2024, Invited

  
• In silico解析技術の提供によるLG研究の加速

  Yoshiki Ikeda

  第1回 L-グルコース研究会, 13 Apr. 2024, Invited

  
• In silico解析によるアカデミア創薬の加速

  池田 幸樹

  角川ドワンゴ学園研究部 研究発表会, 30 Mar. 2024, Invited

  
• 「大学」って何してんの？

  池田 幸樹

  須磨学園中学校・高等学校 キャリアパスセミナー, 31 Jan. 2024, Invited

  
• Academic Drug Development Conference 2023

  Yoshiki Ikeda; Saeko Yanaka

  第46回日本分子生物学会年会, Dec. 2023

  
• Development of “Miniature antibody” technology

  Yoshiki Ikeda

  第46回日本分子生物学会年会, Dec. 2023, Invited

  
• Feel like makin' molecular glue

  Yoshiki Ikeda

  第14回スクリーニング学研究会, Nov. 2023

  
• The 3rd Drug Discovery Conference in Academia

  Yoshiki Ikeda

  第14回スクリーニング学研究会プレカンファレンス, Nov. 2023, Invited

  
• Integrin-related diseases and strategies for their treatment

  Yoshiki Ikeda

  大鵬薬品工業株式会社 講演会, Oct. 2023, Invited

  
• In silico解析によるアカデミア創薬の加速

  池田 幸樹

  愛媛大学理工学研究科応用化学コース シンポジウム, 21 Jul. 2023, Invited

  
• A Design of integrin-miniature for novel therapeutics against virus infections

  Yoshiki Ikeda

  The Molecular Biology Society of Japan, 01 Dec. 2022

  
• A Design of integrin-miniature for novel therapeutics against virus infections

  Yoshiki Ikeda; HIroyuki Takeda; Tatsuo Kinashi

  The Molecular Biology Society of Japan, 01 Dec. 2022

  
• A Design of integrin-miniature for novel therapeutics against virus infections

  Yoshiki Ikeda; Hiroyuki Takeda; Tatsuo Kinashi

  The 13th Conference on Biomolecular Screenology, 25 Nov. 2022

  
• Introduction of Peptide Crafting tool "PeptiCraft"

  Yoshiki Ikeda

  第13回スクリーニング学研究会, 24 Nov. 2022, Invited

  
• The 2nd Annual Conference of Academic Drug Development

  Yoshiki Ikeda

  第13回スクリーニング学研究会, 24 Nov. 2022, Invited

  
• Development of novel peptide crafting tool "PeptiCraft" software

  Yoshiki Ikeda

  高遠シンポジウム, 26 Aug. 2022

  
• Development of novel drug design tools for "In silico-oriented Science"

  Yoshiki Ikeda

  順天堂大学医学部セミナー, 27 May 2022, Invited

  
• Toward establishment for in silico-oriented Science

  Yoshiki Ikeda

  京都大学医学系研究科・セミナー, 16 Dec. 2021, Invited

  
• インテグリン関連疾患治療薬開発に向けた薬剤スクリーニング法の開発

  池田幸樹

  スクリーニング学研究会, 22 Nov. 2019

  
• アカデミア創薬・インテグリン創薬コンソーシアム事業から学ぶアカデミア創薬研究の流れ

  池田幸樹

  スクリーニング学研究会, 21 Nov. 2019

  
• The physiological role of GTP sensing activity of PI5P4Kβ and its evolutional aspects

  Yoshiki Ikeda

  The Molecular Biology Society of Japan 2018, 28 Nov. 2018, Invited

  
• Structure-based screening to identify inhibitor against GTP-sensor kinase, PI5P4Kβ, for cancer therapy.

  Ikeda Y; Takeuchi K; Senda M; Fukunishi Y; Kawaguchi R; Sasaki M; Senda T; Sasaki AT

  UC symposia conference 2018, Apr. 2018, University of Cincinnati

  
• Structure-based screening to identify inhibitor against GTP-sensor kinase, PI5P4Kβ, for cancer therapy.

  Ikeda Y; Takeuchi K; Senda M; Fukunishi Y; Kawaguchi R; Sasaki M; Senda T; Sasaki AT

  Keystone symposia conference 2018, B5: Phosphoinositide Biology: New Therapeutic Targets Beyond Class I PI3K, Feb. 2018

  
• PI5P4Kβ is an intracellular GTP sensor for metabolism and tumorigenesis.

  Ikeda Y; Takeuchi K; Senda M; Nakagawa S; Harada A; Fukunishi Y; Kawaguchi R; Sasaki M; Senda T; Sasaki AT

  Keystone symposia conference 2018, B5: Phosphoinositide Biology: New Therapeutic Targets Beyond Class I PI3K, Feb. 2018, Invited

  
• Toward making “Tumor-buster” which inhibit GTP-sensor kinase, PI5P4Kβ.

  Yoshiki Ikeda

  Seminar at Keio University, Jun. 2017, Invited

  
• Reverse-Structural screening to identify inhibitor against GTP-sensor kinase, PI5P4Kβ, for cancer therapy.

  Ikeda Y; Takeuchi K; Senda M; Fukunishi Y; Senda T; Sasaki AT

  Keystone symposia conference 2017, X3: Tumor Metabolism: Mechanisms and Targets, Mar. 2017

  
• Pharmacological targeting of GTP-energy sensor, PI5P4Kß, as a novel breast cancer therapeutics.

  Ikeda Y; Takeuchi K; Senda M; Fukunishi Y; Senda T; Sasaki AT

  Jensen symposium 2016, Oct. 2016

  

Books and Other Publications

• 実験医学増刊 Vol.35 No.10 がん代謝 ワールブルグを超えて全容解明に挑む

  Joint work, 第2章 がん特異的な代謝 7. GTP代謝

  羊土社, Jun. 2017, Not refereed

  
• 大腸菌におけるRNase EとRNA結合タンパク質Hfq間の相互作用領域の解析

  池田 幸樹

  名古屋大学, Feb. 2011, Not refereed

  

Industrial Property Rights

• 特願2022-183639, Embryo implantation promoting drugs and its screening system

  松浦徹; 池田幸樹; 吉田真子

  
• 特願2022-160708, 窒素含有化合物、前記窒素含有化合物を含む組成物、及び腫瘍悪性度の予測マーカー

  林 美樹夫; 池田幸樹; 岩田 亮一

  
• 特願2022-149604, 抗SARS-CoV-2抗体

  小澤 龍彦; 谷 英樹; 池田 幸樹; 橋口 隆生

  
• 特願P21008JP, Therapeutic drug for myasthenia gravis

  Humiyuki Hattori; Yoshiki Ikeda

  
• 特願2021-055869, Nitrogen-containing compounds, and markers for predicting tumor malignancy

  Mikio Hayashi; Yoshiki Ikeda; Ryoichi Iwata

  

Awards

• 16 Mar. 2023

  教員評価優秀賞　表彰代表者（関西医科大学）
• 17 Mar. 2022

  教員評価優秀賞　表彰代表者（関西医科大学）
• 28 Feb. 2017

  Outstanding HemOnc evals（University of Cincinnati）
• 01 Apr. 2014

  慶應義塾大学奨励研究
• 01 Apr. 2008

  Nagoya University Outstanding Graduate Student Award

Media Coverage

• 富山大など、新型コロナの変異に対抗可能な中和抗体の改良手法を開発

  Rakuten Infoseek, https://news.infoseek.co.jp/article/mynavi_2714319/, 18 Jan. 2024, Internet

  
• 「スーパー中和抗体」オミクロン株にも効果 富山大など改良

  北日本新聞社, https://webun.jp/articles/-/536792, 17 Jan. 2024, Paper

  
• 富山大など、新型コロナの変異に対抗可能な中和抗体の改良手法を開発

  マイナビニュース, https://news.mynavi.jp/techplus/article/20240118-2865009/, 18 Jan. 2024, Internet

  
• 富山大など、新型コロナの変異に対抗可能な中和抗体の改良手法を開発

  BIGLOBEニュース, https://news.biglobe.ne.jp/it/0118/mnn_240118_1662506812.html, 18 Jan. 2024, Internet

  
• 広範なコロナウイルス株に効果のある抗体医薬品を分子シミュレーションにてデザインすることに成功

  日本の研究.com, https://research-er.jp/articles/view/129817, 16 Jan. 2024, Internet

  
• Research team unravels the trick of evolving the GTP sensor

  VERVE TIMES, May 2022, Internet

  
• US-Japan research team unravels the trick of evolving the GTP sensor

  AAAS, EurekAlert, May 2022, Internet

  
• がん細胞の代謝物利用調べる方法確立 創薬や治療戦略などへの応用期待

  荘内日報社, 荘内日報, 12 Nov. 2021, Paper

  
• がん細胞の代謝経路追跡 創薬、治療への応用期待

  山形新聞社, 山形新聞, 10 Nov. 2021, Paper

  
• Effect of Learning Dataset for Identification of Active Molecules

  Med IT Tech, Apr. 2021, Internet

  

External funds: Kakenhi

• 神経膠芽腫治療に向けた革新的な抗体医療技術の開発

  Grant-in-Aid for Scientific Research (B)

  Basic Section 50020:Tumor diagnostics and therapeutics-related

  Kansai Medical University

  池田 幸樹

  From 01 Apr. 2023, To 31 Mar. 2027, Granted

  低分子抗体;ミニチュア化;神経膠芽腫;ADC

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23H02776/
• 中枢神経系の可塑的変化を病態基盤とする慢性疼痛とうつ病の新規分子機序の解明

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51030:Pathophysiologic neuroscience-related

  Kansai Medical University

  片野 泰代

  From 01 Apr. 2022, To 31 Mar. 2026, Granted

  可塑的変化;慢性疼痛;うつ病;網羅解析;シナプス分子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H02960/
• Elucidation of glioma malignant transformation mechanism of integrin activation by Talin-1

  Grant-in-Aid for Scientific Research (C)

  Basic Section 50010:Tumor biology-related

  Kansai Medical University

  Yoshiki IKEDA

  From 01 Apr. 2020, To 31 Mar. 2023, Project Closed

  インテグリン;神経膠芽腫;阻害薬;神経膠腫;シグナル伝達

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K07624/
• 神経膠芽腫治療に向けた革新的な抗体医療技術の開発

  Grant-in-Aid for Scientific Research (B)

  Basic Section 50020:Tumor diagnostics and therapeutics-related

  Kyoto University;Kansai Medical University

  池田 幸樹

  From 01 Apr. 2023, To 31 Mar. 2027, Granted

  インテグリン;VNAR抗体;ミニチュア抗体;低分子抗体;ミニチュア化;神経膠芽腫;ADC

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K27467/
• 中枢神経系の可塑的変化を病態基盤とする慢性疼痛とうつ病の新規分子機序の解明

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51030:Pathophysiologic neuroscience-related

  Kansai Medical University

  片野 泰代

  From 01 Apr. 2022, To 31 Mar. 2026, Granted

  可塑的変化;慢性疼痛;うつ病;網羅解析;シナプス分子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K24221/