Journal of the science of food and agriculture, 30 Mar. 2022, Peer-reviewed, Corresponding author
Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation.
Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses
Yuki Manabe; Yasuho Takii; Tatsuya Sugawara
Journal of Natural Medicines, 20 Jan. 2020, Peer-reviewed, Corresponding author
Studies on Intestinal Absorption and Nutritional Functions of Glycolipids
SUGAWARA Tatsuya
Eiyo To Shokuryo, 10 Feb. 2007
Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1.
Siphonaxanthin, a carotenoid from green algae Codium cylindricum, protects Ob/Ob mice fed on a high-fat diet against lipotoxicity by ameliorating somatic stresses and restoring anti-oxidative capacity.
Jiawen Zheng; Yuki Manabe; Tatsuya Sugawara
Nutrition research (New York, N.Y.), May 2020, Peer-reviewed, Corresponding author
Exopolysaccharides from milk fermented by lactic acid bacteria enhance dietary carotenoid bioavailability in humans in a randomized crossover trial and in rats.
Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model.
Neng Tanty Sofyana; Jiawen Zheng; Yuki Manabe; Yuta Yamamoto; Shigenobu Kishino; Jun Ogawa; Tatsuya Sugawara
Lipids, Mar. 2020, Peer-reviewed, Corresponding author
Niemann-Pick C1-like 1 Promotes Intestinal Absorption of Siphonaxanthin.
Journal of Veterinary Medical Science, 2019, Peer-reviewed
Inhibitory effect of carotenoids on ligand-induced lipid raft translocation of immunoreceptors
Manabe Y; Hirata T; Sugawara T
Journal of Oleo Science, 2019, Peer-reviewed, Corresponding author
Sphingoid bases of dietary ceramide 2-aminoethylphosphonate, a marine sphingolipid, absorb into lymph in rats
Tomonaga N; Tsuduki T; Manabe Y; Sugawara T
Journal of Lipid Research, 2019, Peer-reviewed, Corresponding author
Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells)
Materials Science and Engineering C, 01 Oct. 2018, Peer-reviewed
Poly (D, L-lactide-co-glycolide)-phospholipid nanocarrier for efficient delivery of macular pigment lutein: absorption pharmacokinetics in mice and antiproliferative effect in Hep G2 cells.
Anti-obesity properties of the dietary green Alga, Codium cylindricum, in high-fat diet-induced obese mice
Li Z.-S; Zheng J.-W; Manabe Y; Hirata T; Sugawara T
Journal of Nutritional Science and Vitaminology, 2018, Peer-reviewed, Corresponding author
A role for scavenger receptor B1 as a captor of specific fatty acids in tastbuds of circumvallate papillae
Tsuzuki S; Lee S; Kimoto Y; Sugawara T; Manabe Y; Inoue K
Biomedical Research (Japan), 2018, Peer-reviewed
Identification of Characteristic Components and Foodstuffs in Healthy Japanese Diet and the Health Effects of a Diet with Increased Use Frequency of these Foodstuffs
10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress
TOXICOLOGY AND APPLIED PHARMACOLOGY, Apr. 2016, Peer-reviewed, Corresponding author
Dietary Effects of Oxidized Eicosapentaenoic Acid (EPA) and Intact EPA on Hepatic Steatosis Induced by a High-sucrose Diet and Liver-X-receptor alpha Agonist in Mice
A novel mechanism for improvement of dry skin by dietary milk phospholipids: Effect on epidermal covalently bound ceramides and skin inflammation in hairless mice
JOURNAL OF DERMATOLOGICAL SCIENCE, Jun. 2015, Peer-reviewed
Biodegradable Poly (Lactic-co-Glycolic Acid)-Polyethylene Glycol Nanocapsules: An Efficient Carrier for Improved Solubility, Bioavailability, and Anticancer Property of Lutein
10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPAR gamma and stimulates adipogenesis
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2015, Peer-reviewed
The Green Algal Carotenoid Siphonaxanthin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and the Accumulation of Lipids in White Adipose Tissue of KK-Ay Mice
Molecular species analysis of monosialogangliosides from sea urchin Strongylocentrotus nudus by RPLC-ESI-MS/MS
Pei-Xu Cong; Rui-chang Gao; Chang-Hu Xue; Zhao-Jie Li; Hong-Wei Zhang; Muhammad Naseem Khan; Yong Xue; Tatsuya Sugawara; Jie Xu
FOOD CHEMISTRY, Jan. 2015, Peer-reviewed
High Throughput Analysis of Cerebrosides from the Sea Cucumber Pearsonothria graeffei by Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry
MOLECULAR AND CELLULAR BIOCHEMISTRY, Aug. 2013, Peer-reviewed, Corresponding author
Ardenticatena maritima gen. nov., sp nov., a ferric iron- and nitrate-reducing bacterium of the phylum 'Chloroflexi' isolated from an iron-rich coastal hydrothermal field, and description of Ardenticatenia classis nov.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Aug. 2013, Peer-reviewed
Oxidized eicosapentaenoic acids more potently reduce LXR alpha-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1 beta and GPA than its intact form
Isolation of cytotoxic glucoerebrosides and long-chain bases from sea cucumber Cucumaria frondosa using high speed counter-current chromatography
Jie Xu; Shuang Guo; Lei Du; Yu-Ming Wang; Tatsuya Sugawara; Takashi Hirata; Chang-Hu Xue
Journal of Oleo Science, 06 Mar. 2013, Peer-reviewed
Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5
Zakir Hossain; Tatsuya Sugawara; Takashi Hirata
Oncology Reports, Mar. 2013, Peer-reviewed
Mass spectrometry based N- and C-terminal sequence determination of a hepatopancreas-type prophenoloxidase from the kuruma prawn, Marsupenaeus japonicus
Analysis and Comparison of Glucocerebroside Species from Three Edible Sea Cucumbers Using Liquid Chromatography-Ion Trap-Time-of-Flight Mass Spectrometry
Phytomedicine : international journal of phytotherapy and phytopharmacology, 01 Dec. 2010, Peer-reviewed, Corresponding author
Rapid Quantitative Analysis of Sphingolipids in Seafood Using HPLC with Evaporative Light-Scattering Detection: Its Application in Tissue Distribution of Sphingolipids in Fish
Jingjing Duan; Tatsuya Sugawara; Takashi Hirata
JOURNAL OF OLEO SCIENCE, Sep. 2010, Peer-reviewed, Corresponding author
Analysis of Glucosylceramides from Various Sources by Liquid Chromatography-Ion Trap Mass Spectrometry
JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2009, Peer-reviewed
海洋生物カロテノイドの生理機能
菅原達也; 平田 孝
ニューフードインダストリー, May 2009
EFFECTS OF DIETARY PLANT CEREBROSIDE ON GENE EXPRESSION IN THE LARGE INTESTINE OF 1,2-DIMETHYLHYDRAZINE (DMH)-TREATED MICE DETERMINED BY DNA MICROARRAY ANALYSIS
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Mar. 2009, Peer-reviewed, Lead author, Corresponding author
Food functionality and intestinal absorption of plant glucosylceramides
間 和彦; 菅原達也
The Cell, 2009
The future of fisheries science and the Japanese Society of Fisheries Science Part-III: Action plans for the future of the society IV(5) My notions to the role of the Japanese Society of Fisheries Science
Tatsuya Sugawara
NIPPON SUISAN GAKKAISHI, Nov. 2008, Peer-reviewed
Antioxidative activities of a mycosporine-like amino acid, porphyra-334
Digestion of maize sphingolipids in rats and uptake of sphingadienine by Caco-2 cells
T Sugawara; M Kinoshita; M Ohnishi; J Nagata; M Saito
JOURNAL OF NUTRITION, Sep. 2003, Peer-reviewed, Lead author, Corresponding author
Phospholipids affect the intestinal absorption of carotenoids in mice
Baskaran, V; T Sugawara; A Nagao
LIPIDS, Jul. 2003, Peer-reviewed
Properties and physiological effects of plant cerebroside species as functional lipids
K Aida; N Takakuwa; M Kinoshita; T Sugawara; H Imai; J Ono; M Ohnishi
ADVANCED RESEARCH ON PLANT LIPIDS, 2003, Peer-reviewed
Apoptosis induction by wheat-flour sphingoid bases in DLD-1 human colon cancer cells
T Sugawara; M Kinoshita; M Ohnishi; T Miyazawa
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Oct. 2002, Peer-reviewed
植物のスフィンゴ脂質構成分によるヒト結腸ガン細胞におけるアポトーシス誘導
木下 幹朗; 間 和彦; 高桑 直也; 菅原 達也; 宮澤 陽夫; 小野 治三郎; 大西 正男
脂質生化学研究, 14 Jun. 2002
Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice
T Sugawara; Baskaran, V; W Tsuzuki; A Nagao
JOURNAL OF NUTRITION, May 2002, Peer-reviewed
Method for Quantitative Determination of Cerebroside in “Plant Ceramide” Foodstuffs by High Performance Liquid Chromatography with Evaporative Light Scattering Detection
Minoru Kashima; Kiyotaka Nakagawa; Tatsuya Sugawara; Teruo Miyazawa; Chiaki Murakami; Rumiko Miyashita; Jisaburo Ono; F. S. Deschamps; P. Chaminade
Journal of Oleo Science, 2002, Peer-reviewed
Carotenoids affect proliferation of human prostate cancer cells
E Kotake-Nara; M Kushiro; H Zhang; T Sugawara; K Miyashita; A Nagao
JOURNAL OF NUTRITION, Dec. 2001, Peer-reviewed
Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells
T Sugawara; M Kushiro; H Zhang; E Nara; H Ono; A Nagao
JOURNAL OF NUTRITION, Nov. 2001, Peer-reviewed
Beneficial effect of dietary wheat glycolipids on cecum short-chain fatty acid and secondary bile acid profiles in mice
T Sugawara; T Miyazawa
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, Aug. 2001, Peer-reviewed
光散乱検出による脂質の一斉高感度分析 食品および生体脂質の機能解析への応用に期待
菅原 達也
化学と生物, 25 Jun. 2001
Digestion of plant monogalactosyldiacylglycerol and digalactosyldiacylglycerol in rat alimentary canal
T Sugawara; T Miyazawa
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Mar. 2000, Peer-reviewed
Separation and determination of glycolipids from edible plant sources by high-performance liquid chromatography and evaporative light-scattering detection
T Sugawara; T Miyazawa
LIPIDS, Nov. 1999, Peer-reviewed
Effects of dietary arginine supplementation on protein turnover and tissue protein synthesis in scald-burn rats
XL Cui; M Iwasa; Y Iwasa; Y Ohmori; A Yamamoto; H Meda; M Kume; S Ogoshi; A Yokoyama; T Sugawara; T Funada
Protective function of body pigments from oxidative stress in Panonychus citri
M. Atarashi; Y. Manabe; H. Kishimoto; T. Sugawara; M. Osakabe
8th Symposium of the EURopean Association of ACarologists, Jul. 2016
Characterization of intestinal digestion of Ceramide 2-aminoethylphosphonate, a Marine Sphingolipid
N. Tomonaga; D. Qi; Y. Manabe; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016
Hypolipidemic Effect of Gut Microbial Fatty Acid Metabolites in Hepatocytes
T. Nanthirudjanar; H. Furumoto; J. Zheng; Y.I. Kim; T. Goto; N. Takahashi; T. Kawada; S.B. Park; A. Hirata; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016
A Gut Microbial Fatty Acid Metabolite, 10-Oxo-trans-11-Octadecenoic Acid, is Cytoprotective against Oxidative Stress
H. Furumoto; T. Nanthirudjanar; T. Kume; Y. Izumi; S.B. Park; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016
スフィンゴ脂質によるグルカゴン様ペプチド‐1(GLP‐1)分泌促進効果
旗野翠; 真鍋祐樹; 大日向耕作; 菅原達也
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 01 Sep. 2015
スフィンゴ脂質のグルカゴン様ペプチド‐1(GLP‐1)分泌促進作用
旗野翠; 若山智慧; 長谷川詩歩; 大日向耕作; 菅原達也
日本食品科学工学会大会講演集, 27 Aug. 2015
Carotenoid from green algae effectively suppresses mast cell degranulation via an alteration of cellular sphingomyelin metabolism
Yuki Manabe; Takashi Hirata; Tatsuya Sugawara
The International Chemical Congress of Pacific Basin Societies (Pacifichem) 2015, 2015
Siphonaxanthin a marine carotenoid from green algae attenuates mast cell degranulation by regulating sphingolipid metabolism
Yuki Manabe; Takashi Hirata; Tatsuya Sugawara
12th Asian Congress of Nutrition, 2015
The effect of hydroxy and oxo fatty acids generated by Lactobacillus plantarum on oxidative Stress
IV(5) My notions to the role of the Japanese Society of Fisheries Science(The future of fisheries science and the Japanese Society of Fisheries Science Part-III: Action plans for the future of the society,Symposium)
SUGAWARA TATSUYA; TATSUYA SUGAWARA; Graduate School of Agriculture; Kyoto University
NSUGAF, 15 Nov. 2008
フィコエリスロビリンによる低密度リポタンパク質の酸化抑制効果
菅原達也
脂質生化学研究, 05 Jun. 2008, Peer-reviewed
古細菌膜脂質による脂溶性成分の消化管吸収促進作用
菅原達也
日本油化学会第47回年会, 2008, Peer-reviewed
Effects of Carbon Dioxide on Postharvest Blackening of Alaskan Pink Shrimp Pandalus eous.
Tatsuya Sugawara
5th World Fisheries Congress, 2008, Peer-reviewed
Anti-inflammatory activity of phycoerythrin from Porphyra yezoensis
Tatsuya Sugawara
5th World Fisheries Congress, 2008, Peer-reviewed
ノリの焙焼によるフィコエリスロビリンの生成
菅原達也
平成20年度 日本水産学会近畿支部後期例会, 2008, Peer-reviewed
海洋生物カロテノイドのヒト前骨髄性白血病由来HL‐60細胞に対する細胞致死活性
菅原達也
平成20年度日本水産学会大会, 2008, Peer-reviewed
グルコサミンによる抗炎症作用の評価
菅原達也
第55回日本食品科学工学会, 2008, Peer-reviewed
RBL-2H3細胞を用いたカロテノイドによる脱顆粒抑制機構の解明
菅原達也
第50回日本脂質生化学会, 2008, Peer-reviewed
海洋生物カロテノイドのHL-60細胞に対する細胞致死活性
菅原達也
第11回マリンバイオテクノロジー学会, 2008, Peer-reviewed
海洋生物カロテノイドによる肥満細胞の活性化抑制作用
菅原達也
第11回マリンバイオテクノロジー学会, 2008, Peer-reviewed
植物由来スフィンゴ脂質の消化管吸収
菅原達也
第1回セラミド研究会, 2008, Peer-reviewed
植物由来グルコシルセラミドの経口摂取による免疫賦活効果
菅原達也
第1回セラミド研究会, 2008, Peer-reviewed
CYTOTOXICITY OF MARINE CAROTENOIDS IN HUMAN PROMYELOCYTIC LEUKEMIA HL-60 CELLS
Tatsuya Sugawara
The 15th International Symposium on Carotenoids, 2008, Peer-reviewed
Sea cucumber sphingoid bases induce apotosis in human hepatoma HepG2 cells
Tatsuya Sugawara
5th World Fisheries Congress, 2008, Peer-reviewed
Physiological activities and the applications of glycolipids
菅原 達也; 宮澤 陽夫
Food style 21, May 2007
ナマコ由来スフィンゴ糖脂質の食品機能性の探索
山本 章代; 菅原 達也; 得字 圭彦; 木下 幹朗; 大西 正男; 平田 孝
日本栄養・食糧学会大会講演要旨集, Apr. 2006
植物・真菌由来スフィンゴイド塩基による大腸ガン細胞死の誘導とその機構
木下 幹朗; 間 和彦; 菅原 達也; 小野 治三郎; 櫛 泰典; 宮澤 陽夫; 大西 正男
生化学, Dec. 2003
植物スフィンゴ脂質の消化管内動態
菅原 達也; 木下 幹朗; 宮澤 陽夫; 大西 正男; 斎藤 衛郎
日本栄養・食糧学会大会講演要旨集, Apr. 2003
Microanalysis of Triacylglycerol Hydroperoxides by Chemiluminescence-HPLC Assay
SUGAWARA Tatsuya; MIYAZAWA Teruo
Journal of Oleo Science, 01 Dec. 1999
Presentations
食品成分が腸内環境に及ぼす影響 スフィンゴ脂質の健康機能性
菅原 達也
日本生物工学会大会講演要旨集, Aug. 2019, (公社)日本生物工学会
菌体由来安定同位体ラベル化スフィンゴ脂質の吸収動態の評価
川上祥子; 安藤晃規; 小川順; 友永奈美; 真鍋祐樹; 菅原達也
日本栄養・食糧学会大会講演要旨集, 22 Apr. 2019, (公社)日本栄養・食糧学会
醤油粕由来セラミドの食品機能性の評価
新冨紀奈; 真鍋祐樹; 菅原達也
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 02 Nov. 2018
シフォナキサンチンの抗炎症作用メカニズムの解明
真鍋祐樹; 瀧井靖歩; 友永奈美; 菅原達也
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 02 Nov. 2018
アスタキサンチン経口摂取が脳機能に与える影響
唐錦彩; 小松俊之; 友永奈美; 真鍋祐樹; 菅原達也
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 02 Nov. 2018
スフィンゴ脂質の消化と吸収
菅原達也
消化と吸収, 31 Oct. 2018
消化管と栄養素 スフィンゴ脂質の消化と吸収
菅原 達也
消化と吸収, Oct. 2018, (NPO)日本消化吸収学会
13Cラベル化したスフィンゴ脂質の消化管吸収の評価
塘由惟; 友永奈美; 川上祥子; 安藤晃規; 小川順; 真鍋祐樹; 菅原達也
日本油化学会年会講演要旨集, 04 Sep. 2018
クロマグロ皮スフィンゴミエリンの化学構造の特性
大谷友佑; 開忍; 宮鍋征克; 真鍋祐樹; 菅原達也
日本油化学会年会講演要旨集, 04 Sep. 2018
緑藻シフォナキサンチンの経口摂取が皮膚機能に与える影響
橋本夏希; 中山千華; 真鍋祐樹; 菅原達也
日本油化学会年会講演要旨集, 04 Sep. 2018
シフォナキサンチンの抗炎症作用の特性解析
真鍋祐樹; 菅原達也
日本油化学会年会講演要旨集, 04 Sep. 2018
緑藻類に含まれるカロテノイド資源の調査
林志菜野; 川越大; 林裕一; 真鍋祐樹; 菅原達也
日本微量栄養素学会学術集会講演要旨集, 14 May 2018
Effects of fatty acid metabolites by a gut lactic acid bacterium on lipid metabolism in NASH model mice
Neng Tanty Sofyana; Jiawen Zheng; Yuki Manabe; Yuta Yamamoto; Shigenobu Kishino; Jun Ogawa; Tatsuya Sugawara
2018 AOCS Annual Meeting & Expo, 08 May 2018
Evaluation of Intestinal Absorption of Dietary Sphingolipids
Characterization of intestinal digestion of Ceramide 2-aminoethylphosphonate, a Marine Sphingolipid
N. Tomonaga; D. Qi; Y. Manabe; T. Sugawara
May 2016
Hypolipidemic Effect of Gut Microbial Fatty Acid Metabolites in Hepatocytes
T. Nanthirudjanar; H. Furumoto; J. Zheng; Y.I. Kim; T. Goto; N. Takahashi; T. Kawada; S.B. Park; A. Hirata; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
2016 AOCS Annual Meeting & Expo, May 2016
A Gut Microbial Fatty Acid Metabolite, 10-Oxo-trans-11-Octadecenoic Acid, is Cytoprotective against Oxidative Stress
H. Furumoto; T. Nanthirudjanar; T. Kume; Y. Izumi; S.B. Park; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
K. Aida; N. Takakuwa; M. Kinoshita; T. Sugawara; H. Imai; J. Ono; M. Ohnishi, Contributor, Properties and physiological effects of plant cerebroside species as functional lipids