Journal of the science of food and agriculture, 2022年03月30日, 査読有り, 責任著者
Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation.
Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses
Yuki Manabe; Yasuho Takii; Tatsuya Sugawara
Journal of Natural Medicines, 2020年01月20日, 査読有り, 責任著者
糖脂質の消化管吸収と栄養生理機能に関する研究
菅原 達也
日本栄養・食糧学会誌 : Nippon eiy◆U014D◆ shokury◆U014D◆ gakkaishi = Journal of Japanese Society of Nutrition and Food Science, 2007年02月10日
Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1.
Siphonaxanthin, a carotenoid from green algae Codium cylindricum, protects Ob/Ob mice fed on a high-fat diet against lipotoxicity by ameliorating somatic stresses and restoring anti-oxidative capacity.
Jiawen Zheng; Yuki Manabe; Tatsuya Sugawara
Nutrition research (New York, N.Y.), 2020年05月, 査読有り, 責任著者
Exopolysaccharides from milk fermented by lactic acid bacteria enhance dietary carotenoid bioavailability in humans in a randomized crossover trial and in rats.
Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model.
Neng Tanty Sofyana; Jiawen Zheng; Yuki Manabe; Yuta Yamamoto; Shigenobu Kishino; Jun Ogawa; Tatsuya Sugawara
Lipids, 2020年03月, 査読有り, 責任著者
Niemann-Pick C1-like 1 Promotes Intestinal Absorption of Siphonaxanthin.
Journal of Veterinary Medical Science, 2019年, 査読有り
Inhibitory effect of carotenoids on ligand-induced lipid raft translocation of immunoreceptors
Manabe Y; Hirata T; Sugawara T
Journal of Oleo Science, 2019年, 査読有り, 責任著者
Sphingoid bases of dietary ceramide 2-aminoethylphosphonate, a marine sphingolipid, absorb into lymph in rats
Tomonaga N; Tsuduki T; Manabe Y; Sugawara T
Journal of Lipid Research, 2019年, 査読有り, 責任著者
Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells)
Materials Science and Engineering C, 2018年10月01日, 査読有り
Poly (D, L-lactide-co-glycolide)-phospholipid nanocarrier for efficient delivery of macular pigment lutein: absorption pharmacokinetics in mice and antiproliferative effect in Hep G2 cells.
Anti-obesity properties of the dietary green Alga, Codium cylindricum, in high-fat diet-induced obese mice
Li Z.-S; Zheng J.-W; Manabe Y; Hirata T; Sugawara T
Journal of Nutritional Science and Vitaminology, 2018年, 査読有り, 責任著者
A role for scavenger receptor B1 as a captor of specific fatty acids in tastbuds of circumvallate papillae
Tsuzuki S; Lee S; Kimoto Y; Sugawara T; Manabe Y; Inoue K
Biomedical Research (Japan), 2018年, 査読有り
Identification of Characteristic Components and Foodstuffs in Healthy Japanese Diet and the Health Effects of a Diet with Increased Use Frequency of these Foodstuffs
10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016年04月, 査読有り, 責任著者
Dietary Effects of Oxidized Eicosapentaenoic Acid (EPA) and Intact EPA on Hepatic Steatosis Induced by a High-sucrose Diet and Liver-X-receptor α Agonist in Mice.
Furumoto H; Nanthirudjanar T; Hirata T; Sugawara T
Journal of oleo science, 2016年03月, 査読有り, 責任著者
皮膚に対する作用に注目した食品機能成分の評価
菅原達也
Trace Nutr Res, 2015年12月, 査読有り, 招待有り
Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes
A novel mechanism for improvement of dry skin by dietary milk phospholipids: Effect on epidermal covalently bound ceramides and skin inflammation in hairless mice
Biodegradable Poly (Lactic-co-Glycolic Acid)-Polyethylene Glycol Nanocapsules: An Efficient Carrier for Improved Solubility, Bioavailability, and Anticancer Property of Lutein
10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis.
Goto T; Kim YI; Furuzono T; Takahashi N; Yamakuni K; Yang HE; Li Y; Ohue R; Nomura W; Sugawara T; Yu R; Kitamura N; Park SB; Kishino S; Ogawa J; Kawada T
Biochemical and biophysical research communications, 2015年04月, 査読有り
The Green Algal Carotenoid Siphonaxanthin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and the Accumulation of Lipids in White Adipose Tissue of KK-Ay Mice
Molecular species analysis of monosialogangliosides from sea urchin Strongylocentrotus nudus by RPLC-ESI-MS/MS
Pei-Xu Cong; Rui-chang Gao; Chang-Hu Xue; Zhao-Jie Li; Hong-Wei Zhang; Muhammad Naseem Khan; Yong Xue; Tatsuya Sugawara; Jie Xu
FOOD CHEMISTRY, 2015年01月, 査読有り
High Throughput Analysis of Cerebrosides from the Sea Cucumber Pearsonothria graeffei by Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2013年08月, 査読有り, 責任著者
Ardenticatena maritima gen. nov., sp nov., a ferric iron- and nitrate-reducing bacterium of the phylum 'Chloroflexi' isolated from an iron-rich coastal hydrothermal field, and description of Ardenticatenia classis nov.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2013年08月, 査読有り
Oxidized eicosapentaenoic acids more potently reduce LXRα-induced cellular triacylglycerol via suppression of SREBP-1c, PGC-1β and GPA than its intact form
T. Nanthirudjanar; H. Furumoto; T. Hirata; T. Sugawara
Lipids in Health and Disease, 2013年05月, 査読有り, 責任著者
Isolation of cytotoxic glucoerebrosides and long-chain bases from sea cucumber Cucumaria frondosa using high speed counter-current chromatography
Jie Xu; Shuang Guo; Lei Du; Yu-Ming Wang; Tatsuya Sugawara; Takashi Hirata; Chang-Hu Xue
Journal of Oleo Science, 2013年03月06日, 査読有り
Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5
Zakir Hossain; Tatsuya Sugawara; Takashi Hirata
Oncology Reports, 2013年03月, 査読有り
Mass spectrometry based N- and C-terminal sequence determination of a hepatopancreas-type prophenoloxidase from the kuruma prawn, Marsupenaeus japonicus
Analysis and Comparison of Glucocerebroside Species from Three Edible Sea Cucumbers Using Liquid Chromatography-Ion Trap-Time-of-Flight Mass Spectrometry
Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010年12月01日, 査読有り, 責任著者
Rapid Quantitative Analysis of Sphingolipids in Seafood Using HPLC with Evaporative Light-Scattering Detection: Its Application in Tissue Distribution of Sphingolipids in Fish
Jingjing Duan; Tatsuya Sugawara; Takashi Hirata
JOURNAL OF OLEO SCIENCE, 2010年09月, 査読有り, 責任著者
Analysis of Glucosylceramides from Various Sources by Liquid Chromatography-Ion Trap Mass Spectrometry
EFFECTS OF DIETARY PLANT CEREBROSIDE ON GENE EXPRESSION IN THE LARGE INTESTINE OF 1,2-DIMETHYLHYDRAZINE (DMH)-TREATED MICE DETERMINED BY DNA MICROARRAY ANALYSIS
Effects of dietary plant cerebroside on gene expression in the large intestine of 1,2-dimethylhydrazine (dmh)-treated mice determined by dna microarray analysis
M. Kinoshita; K. Aida; Y. Tokuji; T. Sugawara; M. Ohnishi
Journal of Food Lipids, 2009年05月, 査読有り
Esterification of xanthophylls by human intestinal Caco-2 cells
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2009年03月, 査読有り, 筆頭著者, 責任著者
植物由来グルコシルセラミドの食品機能性と消化吸収
間 和彦; 菅原達也
細胞, 41, 42-44, 2009年
The future of fisheries science and the Japanese Society of Fisheries Science Part-III: Action plans for the future of the society IV(5) My notions to the role of the Japanese Society of Fisheries Science
Tatsuya Sugawara
NIPPON SUISAN GAKKAISHI, 2008年11月, 査読有り
Antioxidative activities of a mycosporine-like amino acid, porphyra-334
Digestion of maize sphingolipids in rats and uptake of sphingadienine by Caco-2 cells
T Sugawara; M Kinoshita; M Ohnishi; J Nagata; M Saito
JOURNAL OF NUTRITION, 2003年09月, 査読有り, 筆頭著者, 責任著者
Phospholipids affect the intestinal absorption of carotenoids in mice
Baskaran, V; T Sugawara; A Nagao
LIPIDS, 2003年07月, 査読有り
Properties and physiological effects of plant cerebroside species as functional lipids
K Aida; N Takakuwa; M Kinoshita; T Sugawara; H Imai; J Ono; M Ohnishi
ADVANCED RESEARCH ON PLANT LIPIDS, 2003年, 査読有り
Apoptosis induction by wheat-flour sphingoid bases in DLD-1 human colon cancer cells
T Sugawara; M Kinoshita; M Ohnishi; T Miyazawa
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2002年10月, 査読有り
植物のスフィンゴ脂質構成分によるヒト結腸ガン細胞におけるアポトーシス誘導
木下 幹朗; 間 和彦; 高桑 直也; 菅原 達也; 宮澤 陽夫; 小野 治三郎; 大西 正男
脂質生化学研究, 2002年06月14日
Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice
T Sugawara; Baskaran, V; W Tsuzuki; A Nagao
JOURNAL OF NUTRITION, 2002年05月, 査読有り
Method for Quantitative Determination of Cerebroside in “Plant Ceramide” Foodstuffs by High Performance Liquid Chromatography with Evaporative Light Scattering Detection
Kashima M; Nakagawa K; Sugawara T; Miyazawa T; Murakami C; Miyashita R; Ono J; Deschamps F.S; Chaminade P
Journal of Oleo Science, 2002年, 査読有り
Carotenoids affect proliferation of human prostate cancer cells
E Kotake-Nara; M Kushiro; H Zhang; T Sugawara; K Miyashita; A Nagao
JOURNAL OF NUTRITION, 2001年12月, 査読有り
Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells
T Sugawara; M Kushiro; H Zhang; E Nara; H Ono; A Nagao
JOURNAL OF NUTRITION, 2001年11月, 査読有り
Beneficial effect of dietary wheat glycolipids on cecum short-chain fatty acid and secondary bile acid profiles in mice
T Sugawara; T Miyazawa
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 2001年08月, 査読有り
光散乱検出による脂質の一斉高感度分析 食品および生体脂質の機能解析への応用に期待
菅原 達也
化学と生物, 2001年06月25日
Digestion of plant monogalactosyldiacylglycerol and digalactosyldiacylglycerol in rat alimentary canal
T Sugawara; T Miyazawa
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2000年03月, 査読有り
Separation and determination of glycolipids from edible plant sources by high-performance liquid chromatography and evaporative light-scattering detection
T Sugawara; T Miyazawa
LIPIDS, 1999年11月, 査読有り
Effects of dietary arginine supplementation on protein turnover and tissue protein synthesis in scald-burn rats
XL Cui; M Iwasa; Y Iwasa; Y Ohmori; A Yamamoto; H Meda; M Kume; S Ogoshi; A Yokoyama; T Sugawara; T Funada
Protective function of body pigments from oxidative stress in Panonychus citri
M. Atarashi; Y. Manabe; H. Kishimoto; T. Sugawara; M. Osakabe
8th Symposium of the EURopean Association of ACarologists, 2016年07月
Characterization of intestinal digestion of Ceramide 2-aminoethylphosphonate, a Marine Sphingolipid
N. Tomonaga; D. Qi; Y. Manabe; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016年
Hypolipidemic Effect of Gut Microbial Fatty Acid Metabolites in Hepatocytes
T. Nanthirudjanar; H. Furumoto; J. Zheng; Y.I. Kim; T. Goto; N. Takahashi; T. Kawada; S.B. Park; A. Hirata; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016年
A Gut Microbial Fatty Acid Metabolite, 10-Oxo-trans-11-Octadecenoic Acid, is Cytoprotective against Oxidative Stress
H. Furumoto; T. Nanthirudjanar; T. Kume; Y. Izumi; S.B. Park; N. Kitamura; S. Kishino; J. Ogawa; T. Hirata; T. Sugawara
107th AOCS Annual Meeting & Expo, 2016年
スフィンゴ脂質によるグルカゴン様ペプチド‐1(GLP‐1)分泌促進効果
旗野翠; 真鍋祐樹; 大日向耕作; 菅原達也
日本栄養・食糧学会近畿支部大会および公開シンポジウム講演抄録集, 2015年09月01日
スフィンゴ脂質のグルカゴン様ペプチド‐1(GLP‐1)分泌促進作用
旗野翠; 若山智慧; 長谷川詩歩; 大日向耕作; 菅原達也
日本食品科学工学会大会講演集, 2015年08月27日
Carotenoid from green algae effectively suppresses mast cell degranulation via an alteration of cellular sphingomyelin metabolism
Yuki Manabe; Takashi Hirata; Tatsuya Sugawara
The International Chemical Congress of Pacific Basin Societies (Pacifichem) 2015, 2015年
Siphonaxanthin a marine carotenoid from green algae attenuates mast cell degranulation by regulating sphingolipid metabolism
Yuki Manabe; Takashi Hirata; Tatsuya Sugawara
12th Asian Congress of Nutrition, 2015年
The effect of hydroxy and oxo fatty acids generated by Lactobacillus plantarum on oxidative Stress
K. Aida; N. Takakuwa; M. Kinoshita; T. Sugawara; H. Imai; J. Ono; M. Ohnishi, 分担執筆, Properties and physiological effects of plant cerebroside species as functional lipids