Basic Information

Affiliated programs (koza)

• Graduate School of Energy Science, エネルギー基礎科学専攻 エネルギー物質科学講座, 教授

Concurrent Affiliation

• Center for the Promotion of Interdisciplinary Education and Research (C-PiER), 非線形・非平衡プラズマ科学研究ユニット

Professional Memberships

• To Present

  The Japan Society of Nucleic Acids Chemistry
• To Present

  Protein Society
• 日本RNA学会
• 高分子学会
• 日本化学会
• アメリカ化学会
• American Association for the Advancement of Science

Academic Degree

• 工学修士(京都大学)
• 工学博士(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 工学研究科, 合成化学専攻, 修士課程修了
• Kyoto University, 工学研究科, 合成化学専攻, 博士後期課程修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 工学部, 合成化学科, 卒業

High School

• High School

  淳心学院高等学校

Research History

• From Apr. 2024

  Kyoto Koka Women's University, The Faculty of Health Science The Department of Health and Nutrition, Professor
• From Aug. 2005, To Mar. 2024

  Kyoto University, Institute of Advanced Energy, Professor
• From 2002

  ：同講師
• From 1998

  ：京都大学エネルギー理工学研究所助手
• From 1992

  ：京都工芸繊維大学繊維学部助手
• From 1990

  ：日本学術振興会特別研究員（PD）
• From 1989

  ：米国カリフォルニア工科大学博士研究員
• From 1988

  ：米国コロンビア大学博士研究員

Language of Instruction

• English
• Japanese

ID,URL

• J-Global ID

  200901078029567090

• External link

  http://www.iae.kyoto-u.ac.jp/material/index-En.html

Website(s) (URL(s))

• http://www.iae.kyoto-u.ac.jp/material/a-12_j.html

researchmap URL

• https://researchmap.jp/read0006627

Research

Research Topics, Overview of the research

• Research Topics

  Nanoassembly of enzymes and receptors to realize artificial metabolic systems
  Exploring functional biomacromolecules by using RNP complexes
  Structure-based design of protein-based biosensors that assess intracellular dynamics of second messengers and metabolites
  Roles of phosphorylation on the fibrils formation by tau

• Overview of the research

  The research interests in our group focus on the design of biomacromolecules and their assemblies for molecular recognition, catalysis and signal transduction in water, the solvent of life. We take synthetic, organic chemical, biochemical and biophysical approaches to understand the biological molecular recognition and chemical reactions. Proteins and protein/nucleic acids assemblies are explored to realize biomimetic function of biological systems, such as visualization of cellular signals by fluorescent biosensors, directed self-assembly of peptides and proteins to build up nanobiomaterials, tailoring artificial receptors and enzymes based on the complex of RNA and a peptide or a protein, and reconstitution of the functional assemblies of receptors and enzymes on the nano architectures. Design strategies for receptors, sensors and enzymes are explored by utilizing structurally well-defined protein domains and protein-RNA complexes. Parallel application of the structure-based design and in vitro selection affords highly specific receptors and sensors for biologically important ligands, such as ATP and the phosphorylated tyrosine residue within a defined amino acid sequence. The information at the biological level, such as the dynamics of the ligand concentration changes, would be translated into a light signal by the fluorescent biosensors to understand the biological signal transduction mechanisms.

Research Interests

• Artificiasl metabolic pathways
• 生体エネルギー
• 人工酵素
• 超分子
• 分子センサー
• 協同性
• 分子認識
• 核酸
• タンパク質

Research Areas

• Nanotechnology/Materials, Molecular biochemistry

Papers

• Enzyme Reactions Are Accelerated or Decelerated When the Enzymes Are Located Near the DNA Nanostructure

  Peng Lin; Tomohiko Hayashi; Huyen Dinh; Eiji Nakata; Masahiro Kinoshita; Takashi Morii

  ACS Applied Materials & Interfaces, 02 Mar. 2025

  
• Artificial Compartments Encapsulating Enzymatic Reactions: Towards the Construction of Artificial Organelles

  Peng Lin; Shiwei Zhang; Futa Komatsubara; Hiroaki Konishi; Eiji Nakata; Takashi Morii

  ChemPlusChem, 07 Nov. 2024

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• Functional Nucleic Acid-Protein Complexes: Application to Fluorescent Ribonucleopeptide Sensors

  Arivazhagan Rajendran; Shiwei Zhang; Takashi Morii

  Handbook of Chemical Biology of Nucleic Acids, 26 Nov. 2022

  
• Front Cover: Topologically‐Interlocked Minicircles as Probes of DNA Topology and DNA‐Protein Interactions (Chem. Eur. J. 22/2022)

  Arivazhagan Rajendran; Kirankumar Krishnamurthy; Seojeong Park; Eiji Nakata; Youngjoo Kwon; Takashi Morii

  Chemistry – A European Journal, 19 Apr. 2022

  
• An Artificial Liposome Compartment with Size Exclusion Molecular Transport

  Shiwei Zhang; Eiji Nakata; Peng Lin; Takashi Morii

  Chemistry – A European Journal, 17 Oct. 2023

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• Near Quantitative Ligation Results in Resistance of DNA Origami Against Nuclease and Cell Lysate

  Kirankumar Krishnamurthy; Arivazhagan Rajendran; Eiji Nakata; Takashi Morii

  Small Methods, 21 Sep. 2023

  
• A Ratiometric Fluorescent Probe for pH Measurement over a Wide Range Composed of Three Types of Fluorophores Assembled on a DNA Scaffold

  Eiji Nakata; Khongorzul Gerelbaatar; Mashal Asif; Hiroaki Konishi; Yuya Shibano; Peng Lin; Takashi Morii

  Chemistry, 17 Aug. 2023

  
• Macropinoscope: Real-Time Simultaneous Tracking of pH and Cathepsin B Activity in Individual Macropinosomes.

  Hisaaki Hirose; Eiji Nakata; Zhengxiao Zhang; Yuya Shibano; Masashi Maekawa; Takashi Morii; Shiroh Futaki

  Analytical chemistry, 01 Aug. 2023

  
• Stimuli-Responsible SNARF Derivatives as a Latent Ratiometric Fluorescent Probe.

  Eiji Nakata; Khongorzul Gerelbaatar; Futa Komatsubara; Takashi Morii

  Molecules (Basel, Switzerland), 24 Oct. 2022

  
• 2TA1-06 Positional effects of phosphorylation upon fibrillation of tau derived peptide(The 47th Annual Meeting of the Biophysical Society of Japan)

  Konno Takashi; Inoue Masafumi; Tainaka Kazuki; Morii Takashi

  Seibutsu Butsuri, 2009

  
• Controlled Assembly of Fluorophores inside a Nanoliposome

  Hiroaki Konishi; Eiji Nakata; Futa Komatsubara; Takashi Morii

  Molecules, Jan. 2023

  
• Enzyme Cascade Reactions on DNA Origami Scaffold

  Eiji Nakata; Huyen Dinh; Peng Lin; Takashi Morii

  Methods in Molecular Biology, 2023

  
• FRET-Based Cathepsin Probes for Simultaneous Detection of Cathepsin B and D Activities

  Zhengxiao Zhang; Eiji Nakata; Yuya Shibano; Takashi Morii

  CHEMBIOCHEM, Oct. 2022

  
• Dynamic Assembly of Cascade Enzymes by the Shape Transformation of a DNA Scaffold

  Peng Lin; Huyen Dinh; Yuki Morita; Eiji Nakata; Takashi Morii

  Advanced Functional Materials, 17 Jan. 2023

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• Mechanistic Aspects for The Modulation of Enzyme Reactions on the DNA Scaffold

  Peng Lin; Hui Yang; Eiji Nakata; Takashi Morii

  Molecules, Sep. 2022

  
• Construction of ribonucleopeptide-based fluorescent sensors for biologically active amines.

  Hasegawa T; Hayashi H; Morii T

  Nucleic acids symposium series (2004), 2007, Peer-reviewed

  
• The Methods to Assemble Functional Proteins on DNA Scaffold and their Applications

  Eiji Nakata; Shiwei Zhang; Huyen Dinh; Peng Lin; Takashi Morii

  DNA Origami, 18 Apr. 2022

  
• Construction of Aptamers and Sensors from RNA-Peptide Complexes by Molecular Evolution

  FUKUDA Masatora; MORII Takashi

  Seibutsu Butsuri, 25 Jul. 2008

  
• SLD2 OXIDATIVE STRAND SCISSION OF DNA

  Matsuura Teruo; Saito Isao; Sugiyama Hiroshi; Morii Takashi

  International Symposium on the Chemistry of Natural Products, 29 May 1988

  
• 2P101 Biochemical modification of pathological protein aggregation(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

  Konno Takashi; Hirata Akiyoshi; Oiki Shigetoshi; Ikura Koji; Morii Takashi

  Seibutsu Butsuri, 2006

  
• A two-step screening to optimize the signal response of an auto-fluorescent protein-based biosensor.

  Shunsuke Tajima; Eiji Nakata; Reiko Sakaguchi; Masayuki Saimura; Yasuo Mori; Takashi Morii

  RSC advances, 17 May 2022

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• Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions.

  Arivazhagan Rajendran; Kirankumar Krishnamurthy; Seojeong Park; Eiji Nakata; Youngjoo Kwon; Takashi Morii

  Chemistry (Weinheim an der Bergstrasse, Germany), 19 Apr. 2022

  
• Topologically-Interlocked Minicircles as Probes of DNA Topology and DNA-Protein Interactions.

  Arivazhagan Rajendran; Kirankumar Krishnamurthy; Seojeong Park; Eiji Nakata; Youngjoo Kwon; Takashi Morii

  Chemistry (Weinheim an der Bergstrasse, Germany), 19 Apr. 2022

  
• Tuning the Reactivity of a Substrate for SNAP-Tag Expands Its Application for Recognition-Driven DNA-Protein Conjugation.

  Zhengxiao Zhang; Eiji Nakata; Huyen Dinh; Masayuki Saimura; Arivazhagan Rajendran; Kazunari Matsuda; Takashi Morii

  Chemistry (Weinheim an der Bergstrasse, Germany), 23 Dec. 2021

  
• Augmentation of an Engineered Bacterial Strain Potentially Improves the Cleanup of PCB Water Pollution.

  Tomijiro Hara; Yumiko Takatsuka; Eiji Nakata; Takashi Morii

  Microbiology spectrum, 22 Dec. 2021

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• Conditional dependence of enzyme cascade reaction efficiency on the inter-enzyme distance.

  Peng Lin; Huyen Dinh; Eiji Nakata; Takashi Morii

  Chemical communications (Cambridge, England), 26 Oct. 2021

  
• Stabilization and structural changes of 2D DNA origami by enzymatic ligation.

  Arivazhagan Rajendran; Kirankumar Krishnamurthy; Amulya Giridasappa; Eiji Nakata; Takashi Morii

  Nucleic acids research, 20 Aug. 2021

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• Dynamic Shape Transformation of a DNA Scaffold Applied for an Enzyme Nanocarrier.

  Peng Lin; Huyen Dinh; Eiji Nakata; Takashi Morii

  Frontiers in chemistry, 2021

  
• Transglutaminase-Catalyzed Cross-Linking and Its Modification of Protein Aggregation

  KONNO Takashi; MORII Takashi; IKURA Koji

  Seibutsu Butsuri, 25 Mar. 2006

  
• Interaction between covalent and non-covalent protein aggregation processes

  Konno T.; Morii T.; Ikura K.

  Seibutsu Butsuri, 2003

  
• 1P-096 Charge-pairing effects upon fibrillation of phosphorylated tau derived peptide(The 46th Annual Meeting of the Biophysical Society of Japan)

  Konno Takashi; Inoue Masafumi; Morii Takashi

  Seibutsu Butsuri, 2008

  
• A facile combinatorial approach to construct a ratiometric fluorescent sensor: application for the real-time sensing of cellular pH changes.

  Eiji Nakata; Hisaaki Hirose; Khongorzul Gerelbaatar; Jan Vincent V Arafiles; Zhengxiao Zhang; Shiroh Futaki; Takashi Morii

  Chemical science, 08 May 2021

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• Evaluation of the role of the DNA surface for enhancing the activity of scaffolded enzymes

  Peng Lin; Huyen Dinh; Yuki Morita; Zhengxiao Zhang; Eiji Nakata; Masahiro Kinoshita; Takashi Morii

  Chemical Communications, Mar. 2021, Peer-reviewed, Last author, Corresponding author

  
• RNA-Peptide Conjugation through an Efficient Covalent Bond Formation

  Shun Nakano; Taiki Seko; Zhengxiao Zhang; Takashi Morii

  APPLIED SCIENCES-BASEL, Dec. 2020, Peer-reviewed, Last author, Corresponding author

  
• Cryogenic Far-Field Fluorescence Nanoscopy: Evaluation with DNA Origami

  Taku Furubayashi; Keita Ishida; Eiji Nakata; Takashi Morii; Kanta Naruse; Michio Matsushita; Satoru Fujiyoshi

  The Journal of Physical Chemistry B, 03 Sep. 2020, Peer-reviewed

  
• Enhanced enzymatic activity exerted by a packed assembly of a single type of enzyme

  Huyen Dinh; Eiji Nakata; Kaori Mutsuda-Zapater; Masayuki Saimura; Masahiro Kinoshita; Takashi Morii

  Chemical Science, Sep. 2020, Peer-reviewed, Last author, Corresponding author

  
• Fluorescence detection of the nitric oxide-induced structural change at the putative nitric oxide sensing segment of TRPC5

  Shunsuke Tajima; Eiji Nakata; Reiko Sakaguchi; Masayuki Saimura; Yasuo Mori; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Apr. 2020

  
• Influence of polymer molecular weight on the properties of in situ synthesized silver-methylcellulose nanocomposite films with a CO2 laser

  Hayato Nishikawa; Eiji Nakata; Shun Nakano; Takashi Nakajima; Takashi Morii

  JOURNAL OF MATERIALS SCIENCE, Feb. 2020

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• Receptor-based fluorescent sensors constructed from ribonucleopeptide

  Shun Nakano; Hiroaki Konishi; Takashi Morii

  Methods in Enzymology, 2020, Peer-reviewed, Last author, Corresponding author

  
• Reaction of ribulose biphosphate carboxylase/oxygenase assembled on a DNA scaffold

  Huyen Dinh; Eiji Nakata; Peng Lin; Masayuki Saimura; Hiroki Ashida; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2019, Peer-reviewed

  
• Nanometer Accuracy in Cryogenic Far-Field Localization Microscopy of Individual Molecules

  Taku Furubayashi; Keita Ishida; Hiromu Kashida; Eiji Nakata; Takashi Morii; Michio Matsushita; Satoru Fujiyoshi

  The Journal of Physical Chemistry Letters, 03 Oct. 2019

  
• Rational design of a DNA sequence-specific modular protein tag by tuning the alkylation kinetics

  Thang Minh Nguyen; Eiji Nakata; Zhengxiao Zhang; Masayuki Saimura; Huyen Dinh; Takashi Morii

  CHEMICAL SCIENCE, Oct. 2019

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• Protein adaptors assemble functional proteins on DNA scaffolds

  Tien Anh Ngo; Huyen Dinh; Thang Minh Nguyen; Fong Fong Liew; Eiji Nakata; Takashi Morii

  CHEMICAL COMMUNICATIONS, Oct. 2019

  
• Highly selective dual sensing of ATP and ADP using fluorescent ribonucleopeptide sensors

  Shun Nakano; Musashi Shimizu; Huyen Dinh; Takashi Morii

  CHEMICAL COMMUNICATIONS, Feb. 2019

  
• Contribution of Coiled-coil Assembly to Ca2+/Calmodulin-dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-associated Phenotypes

  Polat, Onur; Uno, Masatoshi; Maruyama, Terukazu; Tran, Ha; Imamura, Kayo; Wong, Chee Fah; Sakaguchi, Reiko; Ariyoshi, Mariko; Kyohei , Itsuki; Ichikawa, Jun; Morii, Takashi; Shirakawa, Masahiro; Inoue, Ryuji; Asanuma, Katsuhiko; Reiser, Jochen; Tochio, Hidehito; Mori, Yasuo; Mori, Masayuki

  Journal of the American Society of Nephrology, 2019, Peer-reviewed

  
• DNA binding adaptors to assemble proteins of interest on DNA scaffold

  Eiji Nakata; Huyen Dinh; Thang Minh Nguyen; Takashi Morii

  METABOLONS AND SUPRAMOLECULAR ENZYME ASSEMBLIES, 2019, Peer-reviewed

  
• Covalent Bond Formation by Modular Adaptors to Locate Multiple Enzymes on a DNA Scaffold

  Eiji Nakata; Shun Nakano; Arivazhagan Rajendran; Takashi Morii

  Kinetic Control in Synthesis and Self-Assembly, Jan. 2019, Peer-reviewed

  
• Facile conversion of ATP-binding RNA aptamer to quencher-free molecular aptamer beacon

  Yoojin Park; Duangrat Nim-anussornkul; Tirayut Vilaivan; Takashi Morii; Byeang Hyean Kim

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jan. 2018

  
• DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels

  T. Kurokawa; S. Kiyonaka; E. Nakata; M. Endo; S. Koyama; E. Mori; N. H. Tran; H. Dinh; Y. Suzuki; K. Hidaka; M. Kawata; C. Sato; H. Sugiyama; T. Morii; Y. Mori

  Angewandte Chemie, International Edition, 2018, Peer-reviewed

  
• A Diversity-Oriented Library of Fluorophore-Modified Receptors Constructed from a Chemical Library of Synthetic Fluorophores

  Shun Nakano; Tomoki Tamura; Raj Kumar Das; Eiji Nakata; Young-Tae Chang; Takashi Morii

  CHEMBIOCHEM, Nov. 2017, Peer-reviewed

  
• Design of Modular Protein Tags for Orthogonal Covalent Bond Formation at Specific DNA Sequences

  Thang Minh Nguyen; Eiji Nakata; Masayuki Saimura; Huyen Dinh; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Jun. 2017, Peer-reviewed

  
• Nucleic-Acid-Templated Enzyme Cascades

  Arivazhagan Rajendran; Eiji Nakata; Shun Nakano; Takashi Morii

  CHEMBIOCHEM, Apr. 2017, Peer-reviewed

  
• Visualization of organelle-specific thermodynamics

  Yuta Yasuyoshi; Masahiko Hatano; Reiko Sakaguchi; Shigeki Kiyonaka; Itaru Hamachi; Takashi Morii; Takenao Yoshizaki; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• DNA Origami

  MORII Takashi

  POLYMERS, Mar. 2017, Invited

  
• Construction of a library of structurally diverse ribonucleopeptides with catalytic groups

  Tomoki Tamura; Shun Nakano; Eiji Nakata; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Mar. 2017, Peer-reviewed

  
• Spatially Organized Enzymes Drive Cofactor-Coupled Cascade Reactions

  Tien Anh Ngo; Eiji Nakata; Masayuki Saimura; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 2016, Peer-reviewed

  
• Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives

  Eiji Nakata; Yoshihiro Yukimachi; Yoshihiro Uto; Hitoshi Hori; Takashi Morii

  SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, 2016, Peer-reviewed

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• Validating Subcellular Thermal Changes Revealed by Fluorescent Thermosensors

  S. Kiyonaka; R. Sakaguchi; I. Hamachi; T. Morii; T. Yoshizaki; Y. Mori

  Nature Methods, Sep. 2015, Peer-reviewed

  
• Self-Assembled Fluorescent Nanoprobe for the Detection of Fluoride Ions in Aqueous Solutions

  Eiji Nakata; Yoshijiro Nazumi; Yoshihiro Yukimachi; Yoshihiro Uto; Hitoshi Hori; Takashi Morii

  BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Feb. 2015, Peer-reviewed

  
• A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds

  Eiji Nakata; Huyen Dinh; Tien Anh Ngo; Masayuki Saimura; Takashi Morii

  CHEMICAL COMMUNICATIONS, 2015, Peer-reviewed

  
• Phosphorylation regulates fibrillation of an aggregation core peptide in the second repeat of microtubule-binding domain of human tau

  Masafumi Inoue; Shinji Kaida; Shun Nakano; Chiara Annoni; Eiji Nakata; Takashi Konno; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2014, Peer-reviewed

  
• A Neutron Dynamic Therapy with a Boron Tracedrug UTX-51 Using a Compact Neutron Generator

  Hitoshi Hori; Ryu Tada; Yoshihiro Uto; Eiji Nakata; Takashi Morii; Kai Masuda

  ANTICANCER RESEARCH, Aug. 2014, Peer-reviewed

  
• A Neutron Dynamic Therapy with a Boron Tracedrug UTX-51 Using a Compact Neutron Generator

  H. Hori; R. Tada; Y. Uto; E. Nakata; T. Morii; K. Masuda

  ANTICANCER RESEARCH, 10 Jun. 2014, Peer-reviewed

  
• A protein adaptor to locate a functional protein dimer on molecular switchboard

  Tien Anh Ngo; Eiji Nakata; Masayuki Saimura; Tsutomu Kodaki; Takashi Morii

  METHODS, May 2014, Peer-reviewed

  
• Peptidosteroid Tweezers Revisited: DNA Binding Through an Optimised Design

  Lieselot L. G. Carrette; Takashi Morii; Annemieke Madder

  EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, May 2014, Peer-reviewed

  
• A novel strategy to design latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives

  Eiji Nakata; Yoshihiro Yukimachi; Yoshijiro Nazumi; Maki Uwate; Hideaki Maseda; Yoshihiro Uto; Toshihiro Hashimoto; Yasuko Okamoto; Hitoshi Hori; Takashi Morii

  RSC ADVANCES, 2014, Peer-reviewed

  
• Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells

  Shigeki Kiyonaka; Taketoshi Kajimoto; Reiko Sakaguchi; Daisuke Shinmi; Mariko Omatsu-Kanbe; Hiroshi Matsuura; Hiromi Imamura; Takenao Yoshizaki; Itaru Hamachi; Takashi Morii; Yasuo Mori

  NATURE METHODS, Dec. 2013, Peer-reviewed

  
• Toxicity Inspired Cross-Linking for Probing DNA-Peptide Interactions

  Lieselot L. G. Carrette; Takashi Morii; Annemieke Madder

  BIOCONJUGATE CHEMISTRY, Dec. 2013, Peer-reviewed

  
• A Peptide Nucleic Acid (PNA) Heteroduplex Probe Containing an Inosine-Cytosine Base Pair Discriminates a Single-Nucleotide Difference in RNA

  Katsuhiko Matsumoto; Eiji Nakata; Tomoki Tamura; Isao Saito; Yasunori Aizawa; Takashi Morii

  CHEMISTRY-A EUROPEAN JOURNAL, Apr. 2013, Peer-reviewed

  
• Simultaneous detection of ATP and GTP by covalently linked fluorescent ribonucleopeptide sensors

  Shun Nakano; Masatora Fukuda; Tomoki Tamura; Reiko Sakaguchi; Eiji Nakata; Takashi Morii

  Journal of the American Chemical Society, 06 Mar. 2013, Peer-reviewed

  
• Simultaneous detection of ATP and GTP by covalently linked fluorescent ribonucleopeptide sensors

  Shun Nakano; Masatora Fukuda; Tomoki Tamura; Reiko Sakaguchi; Eiji Nakata; Takashi Morii

  Journal of the American Chemical Society, 06 Mar. 2013, Peer-reviewed

  
• Simultaneous Detection of ATP and GTP by Covalently Linked Fluorescent Ribonucleopeptide Sensors

  Shun Nakano; Masatora Fukuda; Tomoki Tamura; Reiko Sakaguchi; Eiji Nakata; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 2013, Peer-reviewed

  
• Arranging enzymes and receptors with nanometer-scale precision on molecular switchboards

  Ngo Anh Tien; Eiji Nakata; Takashi Morii

  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, Jan. 2013, Peer-reviewed

  
• Two Days of Experiments in Vietnam: Asian Chemical Biology Initiative, Hanoi Meeting

  Takashii Morii; Motonari Uesugi

  ACS CHEMICAL BIOLOGY, Apr. 2012, Peer-reviewed

  
• Positional Effects of Phosphorylation on the Stability and Morphology of Tau-Related Amyloid Fibrils

  Masafumi Inoue; Takashi Konno; Kazuki Tainaka; Eiji Nakata; Hiro-o Yoshida; Takashi Morii

  BIOCHEMISTRY, Feb. 2012, Peer-reviewed

  
• Positional Effects of Phosphorylation on the Stability and Morphology of Tau-Related Amyloid Fibrils

  Masafumi Inoue; Takashi Konno; Kazuki Tainaka; Eiji Nakata; Hiro-o Yoshida; Takashi Morii

  BIOCHEMISTRY, Feb. 2012, Peer-reviewed

  
• Assembling functional protein-nucleic acids complexes

  T. Morii

  Dongguk University，Dongguk University，2012.3.16, 2012, Peer-reviewed

  
• Using DNA binding proteins for site-specific positioning of proteins on DNA origami

  E. Nakata; N.A. Tien; F.F. Liew; T. Morii

  ACBC2012，Okinawa，2012.7.4-6, 2012, Peer-reviewed

  
• Novel strategy to control fluorescent property of asymmetric xanthene scaffold toward rationally designable fluorescent probe

  E. Nakata; T. Morii

  ISBC2012，Kanagawa，2012.11.28-30, 2012, Peer-reviewed

  
• Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures

  Eiji Nakata; Fong Fong Liew; Chisana Uwatoko; Shigeki Kiyonaka; Yasuo Mori; Yousuke Katsuda; Masayuki Endo; Hiroshi Sugiyama; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, Peer-reviewed

  
• Construction of ratiometric fluorescent sensors by ribonucleopeptides

  Chiara Annoni; Eiji Nakata; Tomoki Tamura; Fong Fong Liew; Shun Nakano; Maria Luisa Gelmi; Takashi Morii

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, Peer-reviewed

  
• Zinc finger proteins as adaptor for locating proteins at specific addresses of DNA origami

  E. Nakata; L. Fong; C. Uwatoko; S. Kiyonaka; Y. Mori; Y. Katsuda; M. Endo; H. Sugiyama; T. Morii

  Angew. Chem. Int. Ed, 2012, Peer-reviewed

  
• Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures

  Eiji Nakata; Fong Fong Liew; Chisana Uwatoko; Shigeki Kiyonaka; Yasuo Mori; Yousuke Katsuda; Masayuki Endo; Hiroshi Sugiyama; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, Peer-reviewed

  
• Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain

  Kensaku Anraku; Teruhiko Inoue; Kenji Sugimoto; Kota Kudo; Yoshinari Okamoto; Takashi Morii; Yasuo Mori; Masami Otsuka

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2011, Peer-reviewed

  
• A ribonucleopeptide module for effective conversion of an RNA aptamer to a fluorescent sensor

  Fong Fong Liew; Hironori Hayashi; Shun Nakano; Eiji Nakata; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Oct. 2011, Peer-reviewed

  
• Facile conversion of RNA aptamers to modular fluorescent sensors with tunable detection wavelengths

  Shun Nakano; Eiji Nakata; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Aug. 2011, Peer-reviewed

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• Construction of dopamine sensors by using fluorescent ribonucleopeptide complexes

  Fong Fong Liew; Tetsuya Hasegawa; Masatora Fukuda; Eiji Nakata; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Aug. 2011, Peer-reviewed

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• Structural Aspects for the Recognition of ATP by Ribonucleopeptide Receptors

  Shun Nakano; Tsukasa Mashima; Akimasa Matsugami; Masafumi Inoue; Masato Katahira; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 2011, Peer-reviewed

  
• The Mechanism of Fibril Formation of a Non-inhibitory Serpin Ovalbumin Revealed by the Identification of Amyloidogenic Core Regions

  Naoki Tanaka; Yumi Morimoto; Yurika Noguchi; Tomoko Tada; Tomonori Waku; Shigeru Kunugi; Takashi Morii; Yin-Fai Lee; Takashi Konno; Nobuyuki Takahashi

  JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2011, Peer-reviewed

  
• Selective Assembly of Photosynthetic Antenna Proteins into a Domain-Structured Lipid Bilayer for the Construction of Artificial Photosynthetic Antenna Systems: Structural Analysis of the Assembly Using Surface Plasmon Resonance and Atomic Force Microscopy

  Ayumi Sumino; Takehisa Dewa; Masaharu Kondo; Takashi Morii; Hideki Hashimoto; Alastair T. Gardiner; Richard J. Cogdell; Mamoru Nango

  LANGMUIR, Feb. 2011, Peer-reviewed

  
• Design and synthesis of highly solvatochromic fluorescent 2 '-deoxyguanosine and 2 '-deoxyadenosine analogs

  Katsuhiko Matsumoto; Naoya Takahashi; Azusa Suzuki; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Feb. 2011, Peer-reviewed

  
• The Mechanism of Fibril Formation of a Non-inhibitory Serpin Ovalbumin Revealed by the Identification of Amyloidogenic Core Regions

  Naoki Tanaka; Yumi Morimoto; Yurika Noguchi; Tomoko Tada; Tomonori Waku; Shigeru Kunugi; Takashi Morii; Yin-Fai Lee; Takashi Konno; Nobuyuki Takahashi

  JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2011, Peer-reviewed

  
• Recent progress in the construction methodology of fluorescent biosensors based on biomolecules

  MORII Takashi

  Biosensors for Health, Environment and Biosecurity, Feb. 2011, Peer-reviewed

  
• Design and synthesis of highly solvatochromic fluorescent 2 '-deoxyguanosine and 2 '-deoxyadenosine analogs

  Katsuhiko Matsumoto; Naoya Takahashi; Azusa Suzuki; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Feb. 2011, Peer-reviewed

  
• Selective Assembly of Photosynthetic Antenna Proteins into a Domain-Structured Lipid Bilayer for the Construction of Artificial Photosynthetic Antenna Systems: Structural Analysis of the Assembly Using Surface Plasmon Resonance and Atomic Force Microscopy

  Ayumi Sumino; Takehisa Dewa; Masaharu Kondo; Takashi Morii; Hideki Hashimoto; Alastair T. Gardiner; Richard J. Cogdell; Mamoru Nango

  LANGMUIR, Feb. 2011, Peer-reviewed

  
• Reconstitution and AFM observation of photosynthetic membrane protein assembly in planar lipid bilayers

  Ayumi Sumino; Takehisa Dewa; Nobuaki Sasaki; Natsuko Watanabe; Masaharu Kondo; Takashi Morii; Hideki Hashimoto; Mamoru Nango

  e-Journal of Surface Science and Nanotechnology, 29 Jan. 2011, Peer-reviewed

  
• Material Analysis Laboratory in KU-FEL, Kyoto University

  Kyohei Yoshida; Taro Sonobe; Mahoumd Bakr; Tetsuo Sakka; Takashi Sagawa; Eiji Nakata; Takashi Morii; Toshiteru Kii; Kai Masuda; Hideaki Ohgaki

  9TH ECO-ENERGY AND MATERIALS SCIENCE AND ENGINEERING SYMPOSIUM, 2011, Peer-reviewed

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• Modular Functionalization of Ribonucleopeptide Assemblies

  T. Morii

  School of Physical &Mathematical Sciences ， Nanyang Technological University, Singapore，2011.4.13, 2011, Peer-reviewed

  
• A Modular Strategy for Assembling Receptors and Sensors from Ribonucleopeptides

  T. Morii

  2nd Asian 3Round Table on Nucleic Acids，China，2011.10.15, 2011, Peer-reviewed

  
• Design of environmentally sensitive fluorescent 2 '-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probe

  Yuta Shinohara; Katsuhiko Matsumoto; Kenji Kugenuma; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, May 2010, Peer-reviewed

  
• Design of environmentally sensitive fluorescent 2 '-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probe

  Yuta Shinohara; Katsuhiko Matsumoto; Kenji Kugenuma; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, May 2010, Peer-reviewed

  
• Design of environmentally sensitive fluorescent 2 '-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probe

  Yuta Shinohara; Katsuhiko Matsumoto; Kenji Kugenuma; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, May 2010, Peer-reviewed

  
• Design Strategies of Fluorescent Biosensors Based on Biological Macromolecular Receptors

  Kazuki Tainaka; Reiko Sakaguchi; Hironori Hayashi; Shun Nakano; Fong Fong Liew; Takashi Morii

  SENSORS, Feb. 2010, Peer-reviewed

  
• The structural characterization of an ATP-binding ribonucleopeptide receptor

  S. Nakano; M. Fukuda; T. Mashima; M. Katahira; T. Morii

  The 2010 International Chemical Congress of Pacific Basin Societies, Hawaii Convention Center, 2010.12.15-20, 2010, Peer-reviewed

  
• Development of ribonucleopeptide based fluorescent sensors of dopamine

  F.F. Liew; M. Fukuda; K. Tainaka; S. Nakano; T. Morii

  The 2010 International Chemical Congress of Pacific Basin Societies, Hawaii Convention Center, 2010.12.15-20, 2010, Peer-reviewed

  
• Molecular Recognitiom by Ribonucleopeptides

  T. Morii

  Pacifichem 2010, Hawaii Convention Center, 2010.12.19, 2010, Peer-reviewed

  
• An In Vivo Fluorescent Sensor Reveals Intracellular Ins(1,3,4,5)P4 Dynamics in Single Cells

  R Sakaguchi; K Tainaka; N Shimada; S Nakano; M Inoue; S Kiyonaka; Y Mori; T Morii

  Angew. Chem. Int. Ed., 49, 2010, 2010, Peer-reviewed

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• An In Vivo Fluorescent Sensor Reveals Intracellular Ins(1,3,4,5)P-4 Dynamics in Single Cells

  Reiko Sakaguchi; Kazuki Tainaka; Naoko Shimada; Shun Nakano; Masafumi Inoue; Shigeki Kiyonaka; Yasuo Mori; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, Peer-reviewed

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• Light Energy Induced Fluorescence Switching Based on Novel Photochromic Nucleosides

  Katsuhiko Matsumoto; Yoshio Saito; Isao Saito; Takashi Morii

  Green Energy and Technology, 2010, Peer-reviewed

  
• Development of Fluorescent Ribonucleopeptide-Based Sensors for Biologically Active Amines

  Fong Fong Liew; Masatora Fukuda; Takashi Morii

  Green Energy and Technology, 2010, Peer-reviewed

  
• Construction of the Artificial Enzyme for Using Solar Energy

  Shun Nakano; Masatora Fukuda; Kazuki Tainaka; Takashi Morii

  Green Energy and Technology, 2010, Peer-reviewed

  
• Construction of the Functional Biomolecules with the Ribonucleopeptide Complexes

  Masatora Fukuda; Fong Fong Liew; Shun Nakano; Takashi Morii

  Green Energy and Technology, 2010, Peer-reviewed

  
• An In Vivo Fluorescent Sensor Reveals Intracellular Ins(1,3,4,5)P-4 Dynamics in Single Cells

  Reiko Sakaguchi; Kazuki Tainaka; Naoko Shimada; Shun Nakano; Masafumi Inoue; Shigeki Kiyonaka; Yasuo Mori; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, Peer-reviewed

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• Pyrene-labeled deoxyguanosine as a fluorescence sensor to discriminate single and double stranded DNA structures: Design of ends free molecular beacons

  Katsuhiko Matsumoto; Yuta Shinohara; Subhendu S. Bag; Yoshiki Takeuchi; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Nov. 2009, Peer-reviewed

  
• Pyrene-labeled deoxyguanosine as a fluorescence sensor to discriminate single and double stranded DNA structures: Design of ends free molecular beacons

  Katsuhiko Matsumoto; Yuta Shinohara; Subhendu S. Bag; Yoshiki Takeuchi; Takashi Morii; Yoshio Saito; Isao Saito

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Nov. 2009, Peer-reviewed

  
• A single circularly permuted GFP sensor for inositol-1,3,4,5-tetrakisphosphate based on a split PH domain

  Reiko Sakaguchi; Takashi Endoh; Seigo Yamamoto; Kazuki Tainaka; Kenji Sugimoto; Nobutaka Fujieda; Shigeki Kiyonaka; Yasuo Mori; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Oct. 2009, Peer-reviewed

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• Fluorescence switching of photochromic vinylpyrene-substituted 2 '-deoxyguanosine

  Yoshio Saito; Katsuhiko Matsumoto; Yoshiki Takeuchi; Subhendu Sekhar Bag; Satoshi Kodate; Takashi Morii; Isao Saito

  TETRAHEDRON LETTERS, Apr. 2009, Peer-reviewed

  
• Fluorescence switching of photochromic vinylpyrene-substituted 2 '-deoxyguanosine

  Yoshio Saito; Katsuhiko Matsumoto; Yoshiki Takeuchi; Subhendu Sekhar Bag; Satoshi Kodate; Takashi Morii; Isao Saito

  TETRAHEDRON LETTERS, Apr. 2009, Peer-reviewed

  
• Fluorescence switching of photochromic vinylpyrene-substituted 2 '-deoxyguanosine

  Yoshio Saito; Katsuhiko Matsumoto; Yoshiki Takeuchi; Subhendu Sekhar Bag; Satoshi Kodate; Takashi Morii; Isao Saito

  TETRAHEDRON LETTERS, Apr. 2009, Peer-reviewed

  
• Chemical approaches untangling dynamics of cellular signaling molecules

  T Morii

  Kyoto-Oxford University Collaborative Forum, Oxford University, 2009.2.5, 2009, Peer-reviewed

  
• Development of A Fluorescent Ribonucleopeptide Sensor for Histamine

  M Fukuda; H Hayashi; T Hasegawa; T Morii

  Trans. Mat. Res. Soc. Jpn., 34, 525-527, 2009, 2009, Peer-reviewed

  
• Charge-pairing mechanism of phosphorylation effect upon amyloid fibrillation of human tau core peptide

  Masafumi Inoue; Akiyoshi Hirata; Kazuki Tainaka; Takashi Morii; Takashi Konno

  Biochemistry, 11 Nov. 2008, Peer-reviewed

  
• Charge-Pairing Mechanism of Phosphorylation Effect upon Amyloid Fibrillation of Human Tau Core Peptide

  Masafumi Inoue; Akiyoshi Hirata; Kazuki Tainaka; Takashi Morii; Takashi Konno

  BIOCHEMISTRY, Nov. 2008, Peer-reviewed

  
• Context-dependent fluorescence detection of a phosphorylated tyrosine residue by a ribonucleopeptide

  Tetsuya Hasegawa; Masaki Hagihara; Masatora Fukuda; Shun Nakano; Nobutaka Fujieda; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Jul. 2008, Peer-reviewed

  
• Structure-based design of soluble miniature methane monooxygenase hydroxylase

  N Fujieda; M Inoue; Y Tatsuyama; T Morii

  2008 GRC on Enzymes, Coenzymes & Metabolic Pathways, University of New England, 2008.7.13-18, 2008, Peer-reviewed

  
• A Modular Strategy for Development of RNA-Based Fluorescent Sensors

  M Fukuda; T Hasegawa; H Hayashi; T Morii

  Springer, 2008, 2008, Peer-reviewed

  
• 細胞内シグナル伝達物資リアルタイム検出用プローブ

  森井孝

  バイオインダストリー，25，2，7-14，2008, 2008, Peer-reviewed

  
• Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques

  Kensaku Anraku; Teruhiko Inoue; Kenji Sugimoto; Takashi Morii; Yasuo Mori; Yoshinari Okamoto; Masami Otsuka

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, Peer-reviewed

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• Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques

  Kensaku Anraku; Teruhiko Inoue; Kenji Sugimoto; Takashi Morii; Yasuo Mori; Yoshinari Okamoto; Masami Otsuka

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, Peer-reviewed

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• Amyloid-forming propensity of the hydrophobic non-natural amino acid on the fibril-forming core peptide of human tau

  Akiyoshi Hirata; Kenji Sugimoto; Takashi Konno; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jun. 2007, Peer-reviewed

  
• Amyloid-forming propensity of the hydrophobic non-natural amino acid on the fibril-forming core peptide of human tau

  Akiyoshi Hirata; Kenji Sugimoto; Takashi Konno; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jun. 2007, Peer-reviewed

  
• テーラーメイド蛍光センサーの開発

  森井孝

  化学工業, 01 May 2007, Peer-reviewed

  
• Synergistic action of polyanionic and non-polar cofactors in fibrillation of human islet amyloid polypeptide

  Takashi Konno; Shigetoshi Oiki; Takashi Morii

  FEBS LETTERS, Apr. 2007, Peer-reviewed

  
• Synergistic action of polyanionic and non-polar cofactors in fibrillation of human islet amyloid polypeptide

  Takashi Konno; Shigetoshi Oiki; Takashi Morii

  FEBS LETTERS, Apr. 2007, Peer-reviewed

  
• Design of Ribonucleopeptide-based Receptors and Fluorescent Sensors

  T. Morii

  Albany 2007：Conversation 15, State University of New York at Albany, NY, USA, 2007.6.19-23, 2007, Peer-reviewed

  
• Stepwise functionalization of ribonucleopeptides: Optimization of the response of fluorescent ribonucleopeptide sensors for ATP

  Tetsuya Hasegawa; Masaki Hagihara; Masatora Fukuda; Takashi Morii

  NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2007, Peer-reviewed

  
• Nitric oxide activates TRP channels by cysteine S-nitrosylation

  Takashi Yoshida; Ryuji Inoue; Takashi Morii; Nobuaki Takahashi; Shinichiro Yamamoto; Yuji Hara; Makoto Tominaga; Shunichi Shimizu; Yoji Sato; Yasuo Mori

  NATURE CHEMICAL BIOLOGY, Nov. 2006, Peer-reviewed

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• A modular strategy for tailoring fluorescent biosensors from ribonucleopeptide complexes

  Masaki Hagihara; Masatora Fukuda; Tetsuya Hasegawa; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Oct. 2006, Peer-reviewed

  
• A modular strategy for tailoring fluorescent biosensors from ribonucleopeptide complexes

  Masaki Hagihara; Masatora Fukuda; Tetsuya Hasegawa; Takashi Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Oct. 2006, Peer-reviewed

  
• Surface Molecularly Imprinted TiO2 Nanoparticle for Photoreduction of Viologen

  T. Sagawa; M. Kudo; J. HG Steinke; T. Morii; K. Ohkubo

  2006 Materials Research Society Spring Meeting，San Francisco, U.S.A.，2006.4.17-21, 2006, Peer-reviewed

  
• Fabrication of silaffin-like peptide for formation of spherical silica

  N. Fujimoto; A. Hirata; T. Morii; T. Sagawa

  Polymer Preprints, Japan, 2006, Peer-reviewed

  
• 機能性リボヌクレオペプチドをもとにしたケミカルバイオロジー

  森井孝

  バイオ・高分子研究会，片山津温泉，2006.9.22-23, 2006, Peer-reviewed

  
• 酸化チタン超微粒子の表面加工による光誘起電子移動プロセスの効率化

  佐川尚; 工藤繭; 森井孝

  日本化学会第86春季年会，日本大学理工学部船橋キャンパス（千葉），2006.3.27-30, 2006, Peer-reviewed

  
• メタンモノオキシゲナーゼハイドロキシラーゼのαサブユニットを利用した単量体ミニチュア酵素の作製

  井上雅文; 森井孝

  日本化学会第86春季年会，日本大学理工学部船橋キャンパス（千葉），2006.3.27-30, 2006, Peer-reviewed

  
• ウタンパク質コアペプチドの凝集体形成におけるチロシン残基の役割

  平田晃義; 今野卓; 吉川暹; 森井孝

  日本化学会第86春季年会，日本大学理工学部船橋キャンパス（千葉），2006.3.27-30, 2006, Peer-reviewed

  
• イノシトール四リン酸（IP4）に対する細胞内蛍光性バイオセンサーの構築

  坂口怜子; 清中茂樹; 沼賀拓郎; 森泰生; 森井孝

  日本化学会第86春季年会，日本大学理工学部船橋キャンパス（千葉），2006.3.27-30, 2006, Peer-reviewed

  
• ヒスタミンを認識するリボヌクレオペプチドレセプター

  林宏典; 森井孝

  日本化学会第86春季年会，日本大学理工学部船橋キャンパス（千葉），2006.3.27-30, 2006, Peer-reviewed

  
• 「油脂類からのバイオディーゼル燃料」第2章

  森井孝

  バイオメタノールの製造，アイピーシー，2006, 2006, Peer-reviewed

  
• ケミカルバイオロジーのツールとしての機能性ミニチュアタンパク質

  森井孝

  化学工業，57，9，8(656)-12(660)，2006, 2006, Peer-reviewed

  
• RNA-ペプチド複合体をもとにした機能性分子の創製

  福田将虎; 長谷川哲也; 森井孝

  化学フロンティア18「ゲノム化学の最前線ー医学、分子生物学への応用と展開ー」，2006, 2006, Peer-reviewed

  
• ファージディスプレイ法を用いたセレクション－標的分子に結合する生体分子の作製

  福田将虎; 杉本健二; 森井孝

  生命科学研究レター，22，24-29，2006, 2006, Peer-reviewed

  
• Fluorescent ribonucleopeptide sensors

  M. Hagiwara; Y. Tanabe; T. Morii

  2005環太平洋国際化学会議，ハワイ(アメリカ)，2005.12.15-20, 15 Dec. 2005, Peer-reviewed

  
• Construction of optical biosensors to quantitatively assess inositol phosphates

  R. Sakaguchi; S. Kiyonaka; Y. Mori; T. Morii

  2005環太平洋国際化学会議，ハワイ(アメリカ)，2005.12.15-20, 15 Dec. 2005, Peer-reviewed

  
• Ribonucleopeptide receptor recognizing partial structure by each subunit

  M. Fukuda; T. Morii

  2005環太平洋国際化学会議，ハワイ(アメリカ)，2005.12.15-20, 15 Dec. 2005, Peer-reviewed

  
• Sensing of phosphotyrosine residue using the ribonucleopeptide

  T. Hasegawa; S. Yoshikawa; T. Morii

  2005環太平洋国際化学会議，ハワイ(アメリカ)，2005.12.15-20, 15 Dec. 2005, Peer-reviewed

  
• Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1

  A Hirata; M Ueno; Y Aizawa; K Ohkubo; T Morii; S Yoshikawa

  BIOORGANIC & MEDICINAL CHEMISTRY, May 2005, Peer-reviewed

  
• Paradoxical inhibition of protein aggregation and precipitation by transglutaminase-catalyzed intermolecular cross-linking

  T Konno; T Morii; H Shimizu; S Oiki; K Ikura

  JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2005, Peer-reviewed

  
• Paradoxical inhibition of protein aggregation and precipitation by transglutaminase-catalyzed intermolecular cross-linking

  T Konno; T Morii; H Shimizu; S Oiki; K Ikura

  JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2005, Peer-reviewed

  
• Covalent blocking of fibril formation and aggregation of intracellular amyloidgenic proteins by transglutaminase-catalyzed intramolecular cross-linking

  T. Konno; T. Morii; A. Hirata; S.-I. Sato; S. Oiki; K. Ikura

  Biochemistry, 15 Feb. 2005, Peer-reviewed

  
• Covalent blocking of fibril formation and aggregation of intracellular amyloidgenic proteins by transglutaminase-catalyzed intramolecular cross-linking

  Takashi Konno; Takashi Morii; Akiyoshi Hirata; Shin-Ichi Sato; Shigetoshi Oiki; Koji Ikura

  Biochemistry, 15 Feb. 2005, Peer-reviewed

  
• A ribonucleopeptide receptor targets phosphotyrosine

  Tetsuya Hasegawa; Katsutoshi Ohkubo; Susumu Yoshikawa; Takashi Morii

  e-Journal of Surface Science and Nanotechnology, 03 Feb. 2005, Peer-reviewed

  
• Covalent blocking of fibril formation and aggregation of intracellular amyloidgenic proteins by transglutaminase-catalyzed intramolecular cross-linking

  T Konno; T Morii; A Hirata; SI Sato; S Oiki; K Ikura

  BIOCHEMISTRY, Feb. 2005, Peer-reviewed

  
• Covalent blocking of fibril formation and aggregation of intracellular amyloidgenic proteins by transglutaminase-catalyzed intramolecular cross-linking

  T Konno; T Morii; A Hirata; SI Sato; S Oiki; K Ikura

  BIOCHEMISTRY, Feb. 2005, Peer-reviewed

  
• Stepwise molding of a highly selective ribonucleopeptide receptor

  S Sato; M Fukuda; M Hagihara; Y Tanabe; K Ohkubo; T Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Jan. 2005, Peer-reviewed

  
• ライブラリー法による塩基配列特異的DNA 結合性ペプチドの探索

  平田晃義; 森井孝; 大久保捷敏; 吉川暹

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• メタンモノオキシゲナーゼαサブユニットのN末端部位段階的削除による変異体の作製 —再構築に及ぼす影響の評価—

  井上雅文; 大久保捷敏; 森井孝

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• RNAペプチド複合体の段階的高機能化

  福田将虎; 佐藤慎一; 萩原正規; 大久保捷敏; 森井孝

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• ニコチンアミドアデニンジヌクレオチドに対するリボヌクレオペプチドリセプターの開発

  田邊優貴子; 萩原正規; 大久保捷敏; 森井孝

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• リン酸化チロシンを認識する機能性リボヌクレオペプチドの開発

  長谷川哲也; 森井孝; 大久保捷敏; 吉川暹

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• 「ケミカルバイオロジー・ケミカルゲノミクス」 17

  杉本健二; 森井孝; 森泰生; 安楽健作; 岡本良成; 大塚雅巳

  PHドメインを機軸としたmyo-イノシトール誘導体の合成とイノシトール三リン酸センサーの構築，Springer，239-254，2005, 2005, Peer-reviewed

  
• PHドメインを機軸としたmyo-イノシトール誘導体の合成とイノシトール三リン酸センサーの構築

  杉本健二; 森井孝; 森泰生; 安楽健作; 岡本良成; 大塚雅巳

  シュプリンガー・フェアラーク東京・ケミカルバイオロジー・ケミカルゲノミクス, 2005

  
• Novel real-time sensors to quantitatively assess in vivo inositol 1,4,5-trisphosphate production in intact cells

  K Sugimoto; M Nishida; M Otsuka; K Makino; K Ohkubo; Y Mori; T Morii

  CHEMISTRY & BIOLOGY, Apr. 2004, Peer-reviewed

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• Ribonucleopeptides: Functional RNA-peptide complexes

  M Hagihara; T Hasegawa; S Sato; S Yoshikawa; K Ohkubo; T Morii

  BIOPOLYMERS, Apr. 2004, Peer-reviewed

  
• Design of functional RNA-peptide complexes

  T. Hasegawa; M. Fukuda; K. Ohkubo; S. Yoshikawa; T. Morii

  International Society for Nucleosides, Nucleotides & Nucleic Acids XVI International Roundtable，ミネソタ，米国，2004.9.13-16, 2004, Peer-reviewed

  
• Recent advances in biosensing second messengers

  K. Sugimoto; R. Sakaguchi; Y. Mori; T. Morii

  Recent Res. Devel. Chem，2，73-89，2004, 2004, Peer-reviewed

  
• 第一回ケモゲノミクス研究会，2004.9.3

  森井孝

  テーラーメイドレセプターからバイオセンサーへ, 2004, Peer-reviewed

  
• リセプターからセンサーへ

  森井孝

  徳島大学大学院ヘルスバイオサイエンス研究部，2004.7.21, 2004, Peer-reviewed

  
• バイオマスを資源としたCO2ゼロエミッション型エネルギー生産・利用技術の開発

  大久保捷敏; 森井孝; 佐川尚

  京都大学21世紀COEプログラム「環境調和型エネルギーの研究教育拠点形成」中間報告書（平成14〜15年度），222-229，2004, 2004, Peer-reviewed

  
• バイオメタンからのバイオメタノール変換

  大久保捷敏; 森井孝; 佐川尚

  京都大学21世紀COEプログラム「環境調和型エネルギーの研究教育拠点形成」中間報告書（平成14〜15年度），186-193，2004, 2004, Peer-reviewed

  
• Ribonucleopeptide receptors

  Masaki Hagihara; Tetsuya Hasegawa; Shin-ichi Sato; Susumu Yoshikawa; Katsutoshi Ohkubo; Takashi Morii

  Peptide Revolution: Genomics, Proteomics & Therapeutics, 2004, Peer-reviewed

  
• Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLC gamma 2 in B lymphocytes

  M Nishida; K Sugimoto; Y Hara; E Mori; T Morii; T Kurosaki; Y Mori

  EMBO JOURNAL, Sep. 2003, Peer-reviewed

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• Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLC gamma 2 in B lymphocytes

  M Nishida; K Sugimoto; Y Hara; E Mori; T Morii; T Kurosaki; Y Mori

  EMBO JOURNAL, Sep. 2003, Peer-reviewed

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• Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe

  M Mori; T Konno; T Morii; K Nagayama; K Imoto

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2003, Peer-reviewed

  
• Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe

  M Mori; T Konno; T Morii; K Nagayama; K Imoto

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 2003, Peer-reviewed

  
• Functional reassembly of a split PH domain

  K Sugimoto; Y Mori; K Makino; K Ohkubo; T Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 2003, Peer-reviewed

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• Design of Functional Ribonucleopeptide Complexes

  Masaki Hagihara; Shin-ichi Sato; Katsutoshi Ohkubo; Takashi Morii

  The New Frontier of RNA Science，Kyoto, 2003, Peer-reviewed

  
• Design of a ribonucleopeptide biosensor.

  M. Hagihara; A. Hirata; K. Ohkubo; T. Morii

  Nucleic acids research. Supplement (2001), 2003, Peer-reviewed

  
• Optimization of an ATP-binding ribonucleopeptide receptor.

  S. Sato; T. Hasegawa; M. Hagihara; M. Fukuda; K. Ohkubo; T. Morii

  Nucleic acids research. Supplement (2001), 2003, Peer-reviewed

  
• リボヌクレオペプチドによる小分子のセンシング

  萩原正規; 佐藤慎一; 牧野圭祐; 大久保捷敏; 森井孝

  日本化学会第83春期年会，2G8-17，2003, 2003, Peer-reviewed

  
• リン酸化チロシンを認識するリボヌクレオペプチドリセプター

  長谷川哲也; 萩原正規; 佐藤慎一; 吉川暹; 牧野圭祐; 大久保捷敏; 森井孝

  日本化学会第83春期年会，2G8-13，2003, 2003, Peer-reviewed

  
• DNA 認識ペプチドのコンビナトリアル合成

  平田晃義; 大久保捷敏; 吉川暹; 森井孝

  日本化学会第83春季年会，2003.3, 2003, Peer-reviewed

  
• ペプチドライブラリー法を用いたリボヌクレオペプチドリセプターの最適化

  佐藤慎一; 萩原正規; 牧野圭祐; 大久保捷敏; 森井 孝

  日本化学会第83春季年会，2003.3, 2003, Peer-reviewed

  
• Amplification of Ca2+ signaling by Ca2+ entry-dependent translocation and activation of phospholipase C gamma 2 in B lymphocytes.

  M Nishida; K Sugimoto; Y Hara; E Mori; T Morii; T Kurosaki; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2003

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• Chemical approaches untangling sequence-specific DNA binding by proteins

  S Sato; M Hagihara; K Sugimoto; T Morii

  CHEMISTRY-A EUROPEAN JOURNAL, Nov. 2002, Peer-reviewed

  
• In vitro selection of ATP-binding receptors using a ribonucleopeptide complex

  T Morii; M Hagihara; SI Sato; K Makino

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, May 2002, Peer-reviewed

  
• Formation of a fairly stable diazoate intermediate of 5-methyl-2 '-deoxycytidine by HNO2 and NO, and its implication to a novel mutation mechanism in CpG site

  T Suzuki; M Yamada; T Nakamura; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  BIOORGANIC & MEDICINAL CHEMISTRY, Apr. 2002, Peer-reviewed

  
• A new fluorescent biosensor for inositol trisphosphate

  T Morii; K Sugimoto; K Makino; M Otsuka; K Imoto; Y Mori

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Feb. 2002, Peer-reviewed

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• Structure-based design of a leucine zipper protein with new DNA contacting region

  T Morii; S Sato; M Hagihara; Y Mori; K Imoto; K Makino

  BIOCHEMISTRY, Feb. 2002, Peer-reviewed

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• Structure-based design of a leucine zipper protein with new DNA contacting region

  T Morii; S Sato; M Hagihara; Y Mori; K Imoto; K Makino

  BIOCHEMISTRY, Feb. 2002, Peer-reviewed

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• A general strategy to determine a target DNA sequence of a short peptide: Application to a D-peptide

  T Morii; T Tanaka; S Sato; M Hagihara; Y Aizawa; K Makino

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Jan. 2002, Peer-reviewed

  
• A new strategy to determine the target DNA sequence of a short peptide.

  S. Sato; H. Honjyo; S. Tsuji; M. Hagihara; K. Makino; T. Morii

  Nucleic Acids Res Suppl, 2002, Peer-reviewed

  
• オリゴペプチド標的DNA配列の一般的決定法

  佐藤慎一; 田中智久; 萩原正規; 相沢康則; 森井孝; 牧野圭祐

  日本化学会第81春季年会，2F6-10，2002, 2002, Peer-reviewed

  
• 2'-デオキシオキザノシンを含むDNAオリゴマーの合成

  長谷川哲也; 山田真希; 早川芳弘; 山名一成; 森井孝; 牧野圭祐

  日本化学会第81春季年会，3F5-02，2002, 2002, Peer-reviewed

  
• イノシトール三リン酸に対する分子センサーの構築

  杉本健二; 森井孝; 森泰生; 井本敬二; 大塚雅巳; 牧野圭祐

  日本化学会第81春季年会，3F4-35，2002, 2002, Peer-reviewed

  
• 蛍光ラベルを利用したデオキシオキザノシンの検出法

  山田真希; 本庄弘一; 鈴木利典; 森井孝; 牧野圭祐

  日本化学会第81春季年会，2F6-37，2002, 2002, Peer-reviewed

  
• RNA・ペプチド複合体（リボヌクレオペプチド）による分子認識

  萩原正規; 森井孝; 牧野圭祐

  日本化学会第81春季年会，2F6-12，2002, 2002, Peer-reviewed

  
• 短鎖ペプチドによる認識DNA塩基配列決定法の確立

  佐藤慎一; 田中智久; 萩原正規; 相沢康則; 森井孝; 牧野圭祐

  日本化学会第81春季年会，2002.3, 2002, Peer-reviewed

  
• Chemical Approach to Untangle the Sequence-Specific DNA Binding by Proteins.

  森井 孝

  Chem-Eur. J.,22, 5067-5071, 2002, Peer-reviewed

  
• Sequence-specific DNA binding by short peptides

  Takashi Morii; Keisuke Makino

  Advances in DNA Sequence-Specific Agents, 2002, Peer-reviewed

  
• Formation of 2-chloroinosine from guanosine by treatment of HNO2 in the presence of NaCl

  T Suzuki; H Ide; M Yamada; T Morii; K Makino

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2001, Peer-reviewed

  
• A novel detection method for 2\\'-deoxyoxanosine.

  M. Yamada; H. Honjo; T. Hasegawa; E. Morimoto; T. Suzuki; T. Morii; K. Makino

  Nucleic Acids Res Suppl, 2001, Peer-reviewed

  
• Recognition of small molecules by a ribonucleopeptide.

  M. Hagihara; T. Morii; K. Makino

  Nucleic Acids Res Suppl, 2001, Peer-reviewed

  
• デオキシオキザノシンとレリシンの反応

  山田真希; 森本恵弥; 鈴木利典; 森井孝; 牧野圭祐

  日本化学会79春季年会，1F646，2001, 2001, Peer-reviewed

  
• リボヌクレオペプチドによる分子認識

  萩原正規; 森井孝; 牧野圭祐

  日本化学会79春季年会，1F642，2001, 2001, Peer-reviewed

  
• Structure-based designによる新しいDNA結合ドメインの設計とDNA認識機構の解明

  佐藤慎一; 森井孝; 牧野圭祐

  日本化学会79春季年会，1F637，2001, 2001, Peer-reviewed

  
• 生体内シグナル応答性高選択的DNA結合スモールプロテインの創製

  森井孝

  平成12－13年度科学研究費補助金（基盤研究（C）（2））研究成果報告書，2001, 2001, Peer-reviewed

  
• Products of the reaction between a diazoate derivative of 2 '-deoxycytidine and L-lysine and its implication for DNA-nucleoprotein cross linking by NO or HNO2

  T Suzuki; M Yamada; T Nakamura; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  CHEMICAL RESEARCH IN TOXICOLOGY, Dec. 2000, Peer-reviewed

  
• Products of the reaction between a diazoate derivative of 2 '-deoxycytidine and L-lysine and its implication for DNA-nucleoprotein cross linking by NO or HNO2

  T Suzuki; M Yamada; T Nakamura; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  CHEMICAL RESEARCH IN TOXICOLOGY, Dec. 2000, Peer-reviewed

  
• Influence of ring opening-closure equilibrium of oxanine, a novel damaged nucleobase, on migration behavior in capillary electrophoresis

  T Suzuki; M Yamada; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  JOURNAL OF CHROMATOGRAPHY A, Apr. 2000, Peer-reviewed

  
• Identification and characterization of a reaction product of 2 '-deoxyoxanosine with glycine

  T Suzuki; M Yamada; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  CHEMICAL RESEARCH IN TOXICOLOGY, Apr. 2000, Peer-reviewed

  
• Identification and characterization of a reaction product of 2 '-deoxyoxanosine with glycine

  T Suzuki; M Yamada; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  CHEMICAL RESEARCH IN TOXICOLOGY, Apr. 2000, Peer-reviewed

  
• Formation of 2 '-deoxyoxanosine from 2 '-deoxyguanosine and nitrous acid: mechanism and intermediates

  T Suzuki; H Ide; M Yamada; N Endo; K Kanaori; K Tajima; T Morii; K Makino

  NUCLEIC ACIDS RESEARCH, Jan. 2000, Peer-reviewed

  
• In vitro selection of RNA aptamers that respond to a small RNA-binding ligand

  M. hagihara; T. Morii; K. Makino

  環太平洋国際化学会議，Hawaii（米国）, 2000, Peer-reviewed

  
• N2-nitro-2’-deoxyguanosine，a novel DNA lesion，from 2’-deoxyguanosine treated with NO/O2

  M. Tamada,T; Suzuki; K. Kanaori; K. Tajima; T. Morii; K. Makino

  環太平洋国際化学会議，Hawaii（米国）, 2000, Peer-reviewed

  
• 一酸化窒素によるDNA傷害

  山田真希; 鈴木利典; 金折賢二; 田嶋邦彦; 森井孝; 牧野圭祐

  磁気共鳴医学会，2000, 2000, Peer-reviewed

  
• Design of Sequence Specific DNA Binding Peptide Dimers.

  森井 孝

  Protein Science,9, 148, 2000, Peer-reviewed

  
• Formation of 2 '-deoxyoxanosine from 2 '-deoxyguanosine and nitrous acid: mechanism and intermediates

  T Suzuki; H Ide; M Yamada; N Endo; K Kanaori; K Tajima; T Morii; K Makino

  NUCLEIC ACIDS RESEARCH, Jan. 2000, Peer-reviewed

  
• Structure and stability of the consecutive stereoregulated chiral phosphorothioate DNA duplex

  K Kanaori; Y Tamura; T Wada; M Nishi; H Kanehara; T Morii; K Tajima; K Makino

  BIOCHEMISTRY, Dec. 1999, Peer-reviewed

  
• Structure and stability of the consecutive stereoregulated chiral phosphorothioate DNA duplex

  K Kanaori; Y Tamura; T Wada; M Nishi; H Kanehara; T Morii; K Tajima; K Makino

  BIOCHEMISTRY, Dec. 1999, Peer-reviewed

  
• Isolation and characterization of diazoate intermediate upon nitrous acid and nitric oxide treatment of 2 '-deoxycytidine

  T Suzuki; T Nakamura; M Yamada; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  BIOCHEMISTRY, Jun. 1999, Peer-reviewed

  
• Isolation and characterization of diazoate intermediate upon nitrous acid and nitric oxide treatment of 2 '-deoxycytidine

  T Suzuki; T Nakamura; M Yamada; H Ide; K Kanaori; K Tajima; T Morii; K Makino

  BIOCHEMISTRY, Jun. 1999, Peer-reviewed

  
• Stability of the dimerization domain effects the cooperative DNA binding of short peptides

  Y Aizawa; Y Sugiura; M Ueno; Y Mori; K Imoto; K Makino; T Morii

  BIOCHEMISTRY, Mar. 1999, Peer-reviewed

  
• Stability of the dimerization domain effects the cooperative DNA binding of short peptides

  Y Aizawa; Y Sugiura; M Ueno; Y Mori; K Imoto; K Makino; T Morii

  BIOCHEMISTRY, Mar. 1999, Peer-reviewed

  
• Comparison of the sequence-selective dna binding by peptide dimers with covalent and noncovalent dimerization domains

  Yasunori Aizawa; Yukio Sugiura; Takashi Morii

  Biochemistry, 02 Feb. 1999, Peer-reviewed

  
• Comparison of the sequence-selective DNA binding by peptide dimers with covalent and noncovalent dimerization domains

  Y Aizawa; Y Sugiura; T Morii

  BIOCHEMISTRY, Feb. 1999, Peer-reviewed

  
• Comparison of the sequence-selective DNA binding by peptide dimers with covalent and noncovalent dimerization domains

  Y Aizawa; Y Sugiura; T Morii

  BIOCHEMISTRY, Feb. 1999, Peer-reviewed

  
• Kinetic studies of sequence-specific binding of GCN4-bZIP peptides to DNA strands immobilized on a 27-MHz quartz-crystal microbalance

  Y Okahata; K Niikura; Y Sugiura; M Sawada; T Morii

  BIOCHEMISTRY, Apr. 1998, Peer-reviewed

  
• Kinetic studies of sequence-specific binding of GCN4-bZIP peptides to DNA strands immobilized on a 27-MHz quartz-crystal microbalance

  Y Okahata; K Niikura; Y Sugiura; M Sawada; T Morii

  BIOCHEMISTRY, Apr. 1998, Peer-reviewed

  
• Factors governing the sequence-selective DNA binding of geometrically constrained peptide dimers

  T Morii; Y Saimei; M Okagami; K Makino; Y Sugiura

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 1997, Peer-reviewed

  
• Factors governing the sequence-selective DNA binding of geometrically constrained peptide dimers

  T Morii; Y Saimei; M Okagami; K Makino; Y Sugiura

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 1997, Peer-reviewed

  
• Cooperative oligomerization enhances sequence-selective DNA binding by a short peptide

  T Morii; J Yamane; Y Aizawa; K Makino; Y Sugiura

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Oct. 1996, Peer-reviewed

  
• Specific interaction with guanine residues of Z-form DNA by bleomycin-nickel(III) complex

  LL Guan; T Morii; M Otsuka; Y Sugiura

  BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, Aug. 1996, Peer-reviewed

  
• DNA recognition by covalently constrained peptide dimers: roles of the constrains for sequence-selectivity

  M. Okagami; Y. Saimei; K. Makino; T. Morii; Y. Sugiura

  Nucleic Acids Res. Symp. Ser., 35, 163-164 (1996), 1996, Peer-reviewed

  
• SEQUENCE-SPECIFIC DNA-BINDING BY COVALENTLY CONSTRAINED PEPTIDE DIMERS OF THE BASIC LEUCINE-ZIPPER PROTEIN GCN4

  M OKAGAMI; M UENO; K MAKINO; M SHIMOMURA; SAITO, I; T MORII; Y SUGIURA

  BIOORGANIC & MEDICINAL CHEMISTRY, Jun. 1995, Peer-reviewed

  
• SEQUENCE-SPECIFIC DNA-BINDING BY COVALENTLY CONSTRAINED PEPTIDE DIMERS OF THE BASIC LEUCINE-ZIPPER PROTEIN GCN4

  M OKAGAMI; M UENO; K MAKINO; M SHIMOMURA; SAITO, I; T MORII; Y SUGIURA

  BIOORGANIC & MEDICINAL CHEMISTRY, Jun. 1995, Peer-reviewed

  
• RECOGNITION OF NONPALINDROMIC DNA-SEQUENCE BY A PEPTIDE HETERODIMER WITH ARTIFICIAL DIMERIZATION MODULE

  M UENO; M SAWADA; K MAKINO; T MORII

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Nov. 1994, Peer-reviewed

  
• CORRELATIONS OF CRYSTAL-STRUCTURES OF DNA OLIGONUCLEOTIDES WITH ENANTIOSELECTIVE RECOGNITION BY RH(PHEN)(2)PHI(3+) - PROBES OF DNA PROPELLER TWISTING IN SOLUTION

  D CAMPISI; T MORII; JK BARTON

  BIOCHEMISTRY, Apr. 1994, Peer-reviewed

  
• INDUCED FIT OF HELICAL BIPHENYL LIGANDS TO THE DOUBLE-STRANDED DNA

  T MORII; A MURAKAMI; K MAKINO; S MORIMOTO; SAITO, I

  TETRAHEDRON LETTERS, Feb. 1994, Peer-reviewed

  
• INDUCED FIT OF HELICAL BIPHENYL LIGANDS TO THE DOUBLE-STRANDED DNA

  T MORII; A MURAKAMI; K MAKINO; S MORIMOTO; SAITO, I

  TETRAHEDRON LETTERS, Feb. 1994, Peer-reviewed

  
• ARRANGING QUATERNARY STRUCTURE OF PEPTIDES BY CYCLODEXTRIN GUEST INCLUSION COMPLEX - SEQUENCE-SPECIFIC DNA-BINDING BY A PEPTIDE DIMER WITH ARTIFICIAL DIMERIZATION MODULE

  M UENO; A MURAKAMI; K MAKINO; T MORII

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Dec. 1993, Peer-reviewed

  
• STRUCTURAL DETERMINANTS OF ION SELECTIVITY IN BRAIN CALCIUM-CHANNEL

  MS KIM; T MORII; LX SUN; K IMOTO; Y MORI

  FEBS LETTERS, Mar. 1993, Peer-reviewed

  
• SEQUENCE-SPECIFIC DNA-BINDING BY A GEOMETRICALLY CONSTRAINED PEPTIDE DIMER

  T MORII; M SIMOMURA; S MORIMOTO; SAITO, I

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Feb. 1993, Peer-reviewed

  
• Ion-Selection Properties in Brain Calcium Channel.

  森井 孝

  J. Inorg. Biochem.,51, 567, 1993, Peer-reviewed

  
• Rh(phi)2(phen)3+ as a Novel Delivery System For Peptides: Towards Understanding the DNA Recognition Characteristics of Small Peptides.

  森井 孝

  J. Inorg. Biochem.,43, 439, 1991, Peer-reviewed

  
• Measurements of DNA propeller Twisting with Enantiomers of Rh(phen)2(phi)3+.

  森井 孝

  J. Inorg. Biochem.,43, 432, 1991, Peer-reviewed

  
• DNA Recognition by Synthetic Peptides with Dyad Symmetry.

  森井 孝

  J. Inorg. Biochem.,43, 468, 1991, Peer-reviewed

  
• PROBING MICROSTRUCTURES IN DOUBLE-HELICAL DNA WITH CHIRAL METAL-COMPLEXES - RECOGNITION OF CHANGES IN BASE-PAIR PROPELLER TWISTING IN SOLUTION

  AM PYLE; T MORII; JK BARTON

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Dec. 1990, Peer-reviewed

  
• SYNTHETIC COBALT BLEOMYCIN MODELS AS A PHOTOCHEMICAL DNA CLEAVER

  SAITO, I; T MORII; T OBAYASHI; T SERA; H SUGIYAMA; T MATSUURA

  JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, Mar. 1989, Peer-reviewed

  
• PHOTOINDUCED DNA STRAND SCISSION BY COBALT BLEOMYCIN GREEN COMPLEX

  SAITO, I; T MORII; H SUGIYAMA; T MATSUURA; CF MEARES; SM HECHT

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 1989, Peer-reviewed

  
• OXIDATIVE STRAND SCISSION OF DNA

  T MATSUURA; SAITO, I; H SUGIYAMA; T MORII; H KAWABATA

  PURE AND APPLIED CHEMISTRY, Mar. 1989, Peer-reviewed

  
• PHOTOINDUCED DNA STRAND SCISSION BY COBALT BLEOMYCIN GREEN COMPLEX

  SAITO, I; T MORII; H SUGIYAMA; T MATSUURA; CF MEARES; SM HECHT

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 1989, Peer-reviewed

  
• PHOTOINDUCED REACTION .172. REMARKABLY HIGH SELECTIVITY IN PHOTOISOMERIZATION OF TRITHIAZOLES

  SAITO, I; T MORII; S MORI; K YAMAGUCHI; T MATSUURA

  TETRAHEDRON LETTERS, 1988, Peer-reviewed

  
• CHEMISTRY OF 4'-HYDROPEROXY NUCLEOSIDES AS A MODEL FOR THE INTERMEDIATE IN BLEOMYCIN-INDUCED DEGRADATION OF DNA

  SAITO, I; T MORII; T MATSUURA

  JOURNAL OF ORGANIC CHEMISTRY, Mar. 1987, Peer-reviewed

  
• NEW LUMIBLEOMYCIN-CONTAINING THIAZOLYLISOTHIAZOLE RING

  T MORII; SAITO, I; T MATSUURA; J KUWAHARA; Y SUGIURA

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Feb. 1987, Peer-reviewed

  
• PHOTOTRANSFORMED BLEOMYCIN ANTIBIOTICS - STRUCTURE AND DNA CLEAVAGE ACTIVITY

  T MORII; T MATSUURA; SAITO, I; T SUZUKI; J KUWAHARA; Y SUGIURA

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Oct. 1986, Peer-reviewed

  
• PHOTOTRANSFORMED BLEOMYCIN ANTIBIOTICS - STRUCTURE AND DNA CLEAVAGE ACTIVITY

  T MORII; T MATSUURA; SAITO, I; T SUZUKI; J KUWAHARA; Y SUGIURA

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Oct. 1986, Peer-reviewed

  
• RING-SELECTIVE PHOTOREARRANGEMENT OF BITHIAZOLES

  SAITO, I; T MORII; Y OKUMURA; S MORI; K YAMAGUCHI; T MATSUURA

  TETRAHEDRON LETTERS, 1986, Peer-reviewed

  
• A NEW PROCEDURE FOR THE SYNTHESIS OF 2-SUBSTITUTED INDOLES AND 2,2'-BI-INDOLYLS

  SAITO, I; T MORII; S MATSUGO; T MATSUURA

  JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, Peer-reviewed

  

Misc.

• Alteration of p-type channel function by tottering mutations

  M Wakamori; K Yamazaki; T Teramoto; T Mori; K Imoto

  BIOPHYSICAL JOURNAL, Jan. 1999

  
• "かたち"によるDNAの認識--塩基配列を見分ける分子のデザイン

  森井 孝; 斎藤 烈

  化学, Nov. 1991

  
• 核酸認識と金属錯体 (生物無機化学の新展開) -- (生物無機化学をめぐる最近の話題)

  松本 和子; 森井 孝; 杉浦 幸雄

  季刊化学総説, Mar. 1995

  
• フェニルボロン酸を有するPARP阻害型中性子捕捉剤の開発

  藤洸臣; 多田竜; 中田栄司; 増田開; 森井孝; 宇都義浩

  日本薬学会年会要旨集(CD-ROM), 2015

  
• Synthesis and Evaluation of Lignin-Binding Peptides

  中谷祐也; 中谷祐也; 高谷光; 高谷光; 林一広; 中田栄司; 森井孝; 中村正治; 中村正治

  日本化学会春季年会講演予稿集(CD-ROM), 2020

  
• Detection of Inositol Phosphates by Split PH Domains

  Reiko Sakaguchi; Shunsuke Tajima; Yasuo Mori; Takashi Morii

  Methods in Molecular Biology, 2020, Last author, Corresponding author

  
• Reaction of ribulose biphosphate carboxylase/oxygenase assembled on a DNA scaffold.

  Huyen Dinh; Eiji Nakata; Peng Lin; Masayuki Saimura; Hiroki Ashida; Takashi Morii

  Bioorganic & medicinal chemistry, 15 Nov. 2019

  
• DNAオリガミを鋳型にしたリポソームの形成

  小西宏明; DINH Huyen; 脇阪智彦; 中田栄司; 仲野瞬; 森井孝

  日本化学会春季年会講演予稿集(CD-ROM), 01 Mar. 2019

  
• 酵素を“1分子ずつ“狙った場所に配置したDNAナノリアクターの創製

  中田栄司; 森井孝

  日本物理学会講演概要集(CD-ROM), 23 Mar. 2018

  
• 効率的な多段階酵素反応を実現する分子コンビナート

  中田栄司; 森井孝

  バイオサイエンスとインダストリー, 10 Jan. 2018

  
• A Bioorganic Chemistry Approach to Understanding Molecular Recognition in Protein-Nucleic Acid Complexes

  Takashi Morii

  BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, Dec. 2017

  
• ナノレベル間隔で異なる酵素を並べる!―複雑な多段階反応を可能にする分子コンビナートへの挑戦

  中田栄司; 森井孝

  化学, 01 Nov. 2017

  
• 組み換えラッカーゼによるPCB分解の検討

  泉咲綾; 青澤理恵; 家藤治幸; 原富次郎; 高塚由美子; 中田栄司; 森井孝; 渡辺誠也

  日本農芸化学会2017年度大会, 京都市, 2017.3.17-20, 2017

  
• 変異型ビフェニルジオキシゲナーゼを用いたPCB分解特性改変の検討

  青澤理恵; 泉咲綾; 高塚由美子; 原富次郎; 中田栄司; 森井孝; 渡辺 誠也

  日本農芸化学会2017年度大会, 京都市, 2017.3.17-20, 2017

  
• DNA オリガミを利用したナノリポソーム

  H. Konishi; E. Nakata; S. Nakano; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• 蛍光タンパク質を基本骨格とした一酸化窒素センサーの構築

  S. Tajima; E. Nakata; M. saimura; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Enzymatic cascade reactions on the DNA scaffold

  E. NAKATA; H. Dinh; T. Nguyen; M. Saimura; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Catalytic activity of an RNP receptor library with structural diversity

  T. Tamura; S. Nakano; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Orthogonal modular adaptors for assembling multiple enzymes on DNA scaffold

  T. Nguyen; E. Nakata; M. Saimura; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Activity of spatially organized enzyme on DNA scaffold

  H. DINH; E. NAKATA; T. MORII

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Topologically interlocked DNA nanostructures inside a DNA origami

  A. Rajendran; S. Park; 中田栄司; Y. Kwon; 森井孝

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• ATP sensors selected from a fluorophore librar

  S.Nakano; T. Tamura; Y-T. Chang; T. Morii

  The 97th CSJ Annual Meeting, Tokyo, 2017.3.16-20, 2017

  
• Construction of a library of structurally diverse ribonucleopeptides with catalytic groups

  Tomoki Tamura; Shun Nakano; Eiji Nakata; Takashi Morii

  Bioorganic and Medicinal Chemistry, 2017

  
• The efficiency of cascade reactions by spatially organized enzymes on DNA scaffold

  E. Nakata; T.A. Ngo; M. Saimura; T. Morii

  Asian 3 Roundtable on Nucleic Acids and Chemical Probe Research Hub, Fukuoka 2016, Fukuoka city, 2016.9.22-24, 2016

  
• Screening of ribonucleopeptide receptor-based sensors by using fluorophore library

  S. Nakano; T. Tamura; Y.T. Chang; T. Morii

  Asian 3 Roundtable on Nucleic Acids and Chemical Probe Research Hub, Fukuoka 2016, Fukuoka city, 2016.9.22-24, 2016

  
• Activity of the assembled enzyme on DNA scaff old

  H.T.T. Dinh; E. Nakata; T.A. Ngo; T. Morii

  Asian 3 Roundtable on Nucleic Acids and Chemical Probe Research Hub, Fukuoka 2016, Fukuoka city, 2016.9.22-24, 2016

  
• Evaluation of orthogonal modular adaptors for assembling proteins on DNA scaff old

  T.M. Nguyen; E. Nakata; M. Saimura; T. Morii

  Asian 3 Roundtable on Nucleic Acids and Chemical Probe Research Hub, Fukuoka 2016, Fukuoka city, 2016.9.22-24, 2016

  
• Assembling enzymes on a DNA scaffold

  E. Nakata; T. Morii

  Asian 3 Roundtable on Nucleic Acids and Chemical Probe Research Hub, Fukuoka 2016, Fukuoka city, 2016.9.22-24, 2016

  
• 構造多様性を有するRNP リセプターライブラリーの構築

  田村友樹; 仲野瞬; 森井孝

  第10回バイオ関連化学シンポジウム, 金沢市, 2016.9.7-9, 2016

  
• 蛍光分子ライブラリーを利用したリボヌクレオペプチドセンサーの構築

  仲野瞬; 田村友樹; Chang Young-Tae; 森井孝

  第10回バイオ関連化学シンポジウム, 金沢市, 2016.9.7-9, 2016

  
• 蛍光タンパク質を基本骨格とした一酸化窒素センサー

  田嶋竣介; 中田栄司; 才村正幸; 森井孝

  第10回バイオ関連化学シンポジウム, 金沢市, 2016.9.7-9, 2016

  
• DNAナノ構造体に酵素を配置した分子スイッチボード

  中田栄司; Ngo Anh Tien; Dinh Huyen; Nguyen Minh Thang; 才村正幸; 森井孝

  第10回バイオ関連化学シンポジウム, 金沢市, 2016.9.7-9, 2016

  
• DNA ナノ構造体に酵素を配置した分子スイッチボードの開発

  中田栄司; 森井孝

  第14回ホスト・ゲスト化学シンポジウム, 高知市, 2016.6.4-5, 2016

  
• Expansion of modular adaptors for covalently locating a number of proteins on DNA nanostructure

  Eiji Nakata; Thang Minh Nguyen; Masayuki Saimura; Takashi Morii

  ICIRS16, 宇治市, 2016.3.7, 2016, Peer-reviewed

  
• Construction of an enzyme assembly on DNA scaffold via a modular adaptor

  Huyen Dinh; Eiji Nakata; Tien Anh Ngo; Masayuki Saimura; Takashi Morii

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• Development of orthogonal modular adaptars for assembling multiple proteins on DNA nanostructure

  Thang Minh Nguyen; Eiji Nakata; Masayuki Saimura; Takashi Morii

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• Factor governing the efficiency of cascade reactions by spacially organized enzymes

  Tien Anh Ngo; Eiji Nakata; Masayuki Saimura; Takashi Morii

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• 金属イオン錯体を導入したリボヌクレオペプチドによるエステル加水分解

  有山健太; 田村友樹; 仲野瞬; 森井孝

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• リボヌクレオペプチドによるエステル加水分解

  田村友樹; 仲野瞬; 有山健太; 森井孝

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• 蛍光分子ライブラリーを利用したリボヌクレオペプチドセンサーのスクリーニング

  仲野瞬; 田村友樹; Chang Young-Tae; 森井孝

  日本化学会第96春季年会, 京田辺市, 2016.3.24-27, 2016, Peer-reviewed

  
• DNA origamiを用いたイオンチャネル集積化法の開発

  黒川 竜紀; 清中 茂樹; 中田 栄司; 遠藤 政幸; 小山 祥平; 森 恵美子; 矢野 将太郎; 鈴木 勇輝; 日高 久美; 川田 正晃; 佐藤 主税; 杉山 弘; 森井 孝; 森 泰生

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

  
• Veliparibをリードとしたホウ素含有PARP阻害剤の創製

  宇都義浩; 多田竜; 遠藤秀彰; 堀均; 増田開; 中田栄司; 森井孝

  第17回癌治療増感研究シンポジウム, Feb. 2015

  
• Development of modular adaptors to covalently locate multiple enzymes on DNA nanoscaffold

  Thang Minh Nguyen; Eiji Nakata; Huyen Dinh; Tien Anh Ngo; Masayuki Saimura; Takashi Morii

  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015), Hawaii, 2015.12.15-20, 2015, Peer-reviewed

  
• Specific detection of ATP by fluorescent ribonucleopeptide sensors

  Shun Nakano; Tomoki Tamura; Takashi Morii

  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015), Hawaii, 2015.12.15-20, 2015, Peer-reviewed

  
• Construction and screening of the RNP library with catalytic functional group

  Tomoki Tamura; Kenta Ariyama; Shun Nakano; Takashi Morii

  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015), Hawaii, 2015.12.15-20, 2015, Peer-reviewed

  
• Development of various types of protein adaptors to locate a single molecule of functional protein on molecular switchboard

  Tien Anh Ngo; Eiji Nakata; Huyen Dinh; Thang Minh Nguyen; Masayuki Saimura; Takashi Morii

  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015), Hawaii, 2015.12.15-20, 2015, Peer-reviewed

  
• Rational design of latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives

  Eiji Nakata; Takashi Morii

  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015), Hawaii, 2015.12.15-20, 2015, Peer-reviewed

  
• Site-specific covalent modification of individual protein molecule on DNA nanoscaffold

  Eiji Nakata; Huyen Dinh; Nguyen Minh Thang; Ngo Tien Anh; Masayuki Saimura; Takashi Morii

  ISNAC2015 第42回国際核酸化学シンポジウム, 姫路市, 2015.9.25, 2015, Peer-reviewed

  
• Expansion of modular adaptors for covalently locating multiple enzymes on DNA nanoscaffold

  Thang Minh Nguyen; Eiji Nakata; Masayuki Saimura; Takashi Morii

  ISNAC2015 第42回国際核酸化学シンポジウム, 姫路市, 2015.9.24, 2015, Peer-reviewed

  
• Construction of DNA nanotubes toward the three-dimensionally constrained assembly of enzymes

  Keisuke Nishida; Huyen Dinh; Eiji Nakata; Takashi Morii

  ISNAC2015 第42回国際核酸化学シンポジウム, 姫路市, 2015.9.24, 2015, Peer-reviewed

  
• Evaluation of the cluster effect by systematically assembling ATP-binding RNP receptors on DNA origami

  ANNONI, Chiara; NAKANO, Shun; YOSHIMURA, Yuki; NAKATA, Eiji; MORII, Takashi

  日本化学会第95春季年会2015, 千葉市, 2015.3.26-29, 2015, Peer-reviewed

  
• Orthogonal assembly of RuBisCO and Carbonic Anhydrase on a DNA nanoscaffold

  DINH, Huyen; NAKATA, Eiji; NGO, Tien Anh; ASHIDA, Hiroki; YOKOTA, Akiho; MORII, Takashi

  日本化学会第95春季年会2015, 千葉市, 2015.3.26-29, 2015, Peer-reviewed

  
• DNAナノ構造体に機能性タンパク質を配置した分子スイッチボードの開発

  中田栄司; 森井孝

  Workshop in 富山大学, 富山市, 2015.11.18, 2015, Peer-reviewed

  
• 三次元的な酵素配置を目指したDNA ナノチューブの構築

  西田圭佑; Dinh Huyen; 中田栄司; 森井孝

  第9回バイオ関連化学シンポジウム, 熊本市, 2015.9.11, 2015, Peer-reviewed

  
• DNAナノ構造体への共有結合型DNA結合アダプターを介した酵素の配置

  中田栄司; Huyen Dinh; Nguyen Minh Thang; Ngo Tien Anh; 才村正幸; 森井孝

  第9回バイオ関連化学シンポジウム, 熊本市, 2015.9.11, 2015, Peer-reviewed

  
• 集積化したリセプターの基質選択性評価

  吉村祐輝; ANNONI Chiara; 仲野瞬; 中田栄司; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• タグタンパク質を融合したDNA結合アダプターによるDNAナノ構造体とタンパク質間の共有結合形成

  戸田昂人; 中田栄司; 才村正幸; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• 共有結合を介したDNAナノ構造体へのDNA結合アダプター融合タンパク質の配置

  佐々木謙太; 中田栄司; 才村正幸; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• DNAナノ構造体上に配置した酵素集合体の機能評価

  NGO Anh Tien; 中田栄司; 才村正幸; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• タンパク質の選択的な配置を目指したDNAナノチューブの構造制御

  西田圭佑; DINH Huyen; NGO Anh Tien; 中田栄司; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• ATPのピロリン酸部位を識別する蛍光性センサーの作製

  仲野瞬; 田村友樹; 森井孝

  日本化学会第95春季年会2015, 千葉県, 2015.3.26-29, 2015, Peer-reviewed

  
• DNA origamiに機能性タンパク質を固定化した分子スイッチボードの開発

  中田 栄司; 森井 孝

  分子 ロボティクス研究会 in 鳥取, 鳥取県, 2015.01.23, 2015

  
• Assessment of both equilibrium and kinetic aspects of ATP-binding ribonucleopeptide (RNP) clusters arranged on DNA nanoscaffold

  C. Annoni; S. Nakano; E. Nakata; Y. Yoshimura; T. Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Application of DNA binding proteins for assembling proteins RuBisCO and Carbonic Anhydrase on DNA nanoscaffold

  H. Dinh; E. Nakata; T.A. Ngo; H. Ashida; A. Yokota; T. Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Ribonucleopeptides with catalytic functional groups

  T. Tamura; K. Ariyama; S. Nakano; T. Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Evaluation of the substrate selectivity of clustered ATP-binding RNA aptamers.

  Y. Yoshimura; C. Annoni; S. Nakano; E. Nakata; T. Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Construction of ATP sensor with high specificity for the pyrophosphate moiety

  S. Nakano; T. Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Site-specific and Covalent Modification of a Single Protein Molecule on DNA Nanoscaffold

  Eiji Nakata; Dinh Huyen; Tien Anh Ngo; Masayuki Saimura; Takashi Morii

  ISNAC2014 第41回国際核酸化学シンポジウム, 福岡市, 2014.11.5, 2014, Peer-reviewed

  
• Molecular Switchboard: Assembling Multiple Proteins on DNA Origami

  Eiji NAKATA; Takashi MORII

  Kyoto-Bordeaux Symposium, Bordeaux, 2014.5.5, 2014, Peer-reviewed

  
• Applications of sequence-specific DNA binding adaptors for assembling proteins on DNA origami

  H.T.T. Dinh; E. Nakta; A.T. Ngo; H. Ashida; A. Yokota; T. Morii

  日本化学会第94春季年会(2014), 名古屋大学, 2014.3.29, 2014, Peer-reviewed

  
• Construction of organized assembly of enzymes on DNA origami

  T.A. Ngo; E. Nakata; M. Saimura; T. Kodaki; T. Morii

  日本化学会第94春季年会(2014), 名古屋大学, 2014.3.29, 2014, Peer-reviewed

  
• Construction of talor-made receptors and sensors from RNA-peptide complex

  T. Tamura; C. Annoni; E. Nakata; F.F. Liew; S. Nakano; T. Morii

  2014 Kyoto-Ajou Joint Symposium, 2014.2.25, 2014, Peer-reviewed

  
• Construction of a Molecular Switchboard by Using Monomeric and Homodimeric Protein Adaptors

  T.A. Ngo; E. Nakata; M. Saimura; T. Kodaki; T. Morii

  2014 Kyoto-Ajou Joint Symposium, 2014.2.25, 2014, Peer-reviewed

  
• DNA origamiに機能性タンパク質を固定化した分子スイッチボード開発

  中田栄司; Ngo Tien Anh; Dinh Huyen; 仲野瞬; 才村正幸; 小; 森井孝

  第63回高分子討論会, 長崎県, 2014.9.26, 2014, Peer-reviewed

  
• Application of DNA binding adaptors for assembling protein RuBisCO on DNA nano-scaffold

  Dinh Huyen; 中田栄司; Ngo Anh Tien; 蘆田弘樹; 横田明穂; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• DNAナノ構造体上に配置したATP結合性RNPリセプタ一の集積効果

  Annoni Chiara; 仲野瞬; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• 非天然活性中心を導入したリボヌクレオペプチドの触媒活性

  田村友樹; 有山健太; 仲野瞬; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• タグンパク質融合アダプーを用いたDNA ナノ構造体への 共有結合によるタンパク質ナノ構造体への配置

  戸田昂人; 中田栄司; Ngo Anh Tien; Huyen Dinh; 才村正幸; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• 集積化したRNAアプタマーの基質選択性評価

  吉村祐輝; アンノーニ キアラ; 仲 瞬; 中田栄司; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• ピロリン酸部位の識別が可能なATPセンサーの作製と機能評価

  仲野瞬; 森井孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• DNAナノ構造体へのタンパク質一分子固定化法

  中田 栄司; Huyen Dinh; Ngo Tien Anh; 才村 正幸; 小瀧; 努; 森井 孝

  第8回バイオ関連化学シンポジウム, 岡山市, 2014.9.11, 2014, Peer-reviewed

  
• 非天然触媒分子を導入したリボヌクレオペプチド

  田村友樹; 有山健太; 仲野瞬; 森井孝

  第46回若手ペプチド夏の勉強会, 京都市, 2014.8.3, 2014, Peer-reviewed

  
• ATP-binding RNP receptors assembled on DNA nano-scaffold

  Annoni Chiara; 吉村祐輝; 仲野瞬; 中田栄司; 森井孝

  第46回若手ペプチド夏の勉強会, 京都市, 2014.8.3, 2014, Peer-reviewed

  
• リボヌクレオペプチドを用いた蛍光性センサー

  仲野瞬; 田村友樹; Annoni Chiara; 中田栄司; 森井孝

  第46回若手ペプチド夏の勉強会, 京都市, 2014.8.3, 2014, Peer-reviewed

  
• 反応活性中心を導入したリボヌクレオペプチドの触媒活性

  田村友樹; 仲野瞬; 吉村祐輝; 中田栄司; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.29, 2014, Peer-reviewed

  
• DNAオリガミへの機能性タンパク質の1分子固定化:DNA結合アダプターとDNAオリガミとの共有結合形成

  戸田昂人; Ngo Anh Tien; Huyen Thi Thu Dinh; 佐々木謙太; 中田栄司; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.28, 2014, Peer-reviewed

  
• DNAオリガミへの機能性タンパク質の１分子固定化 :共有結合型DNA結合アダプターの開発

  佐々木謙太; 戸田昂人; 中田栄司; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.28, 2014, Peer-reviewed

  
• 異なるアミノ酸配列のタウペプチド共存下での繊維形成

  馬場あゆみ; 井上雅文; 今野卓; 仲野瞬; 中田栄司; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.28, 2014, Peer-reviewed

  
• DNAオリガミを用いたRNAアプタマーの集積効果の評価

  吉村祐輝; ANNONI Chiara; 仲野瞬; 中田栄司; GELMI Maria LUISA; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.27, 2014, Peer-reviewed

  
• 共有結合化蛍光性リボヌクレオペプチドセンサーの作製とその応用

  仲野瞬; 田村友樹; 中田栄司; 森井孝

  日本化学会第94春季年会, 名古屋大学, 2014.3.27, 2014, Peer-reviewed

  
• Molecular Switchboard: Assembling Multiple Proteins on DNA Origami

  E. Nakata; T. Morii

  The second Kyoto-Bristol symposium 2014, Kyoto University, 2014.1.9, 2013, Peer-reviewed, Invited

  
• Development of a homodimeric adaptor for constructing an artificial protein assembly on molecular switchboard

  T.A. Ngo; E. Nakata; M. Saimura; T. Kodaki; T. Morii

  The 40th International Symposium on Nucleic Acids Chemistry, Kanagawa University, 2013.11.14, 2013, Peer-reviewed

  
• Site-specific covalent modification of DNA origami by functional proteins

  E. Nakata; H.T.T. Dinh; T.A. Ngo; M. Saimura; T. Morii

  The 40th International Symposium on Nucleic Acids Chemistry, Kanagawa University, 2013.11.14, 2013, Peer-reviewed

  
• Construction of a molecular switchboard by assembling ribonucleopeptide biosensors

  C. Annoni; F.F. Liew; S. Nakano; E. Nakata; M.L. Gelmi; T. Morii

  The 40th International Symposium on Nucleic Acids Chemistry, Kanagawa University, 2013.11.13, 2013, Peer-reviewed

  
• A rational design strategy to design latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives

  E. Nakata; T. Morii

  7th ISNM2013 7th international symposium on nanomedicine, Kyushu Institute of Technology, 2013.11.8, 2013, Peer-reviewed

  
• A rational design strategy to control fluorescent property of SNARF toward latent ratiometric fluorescent pH probe

  E. Nakata; T. Morii

  NMMS2013, Tokyo University, 2013.10.8, 2013, Peer-reviewed

  
• Development of an aritificial protein assembly on molecular switchboard

  T.A. Ngo; E. Nakata; M. Saimura; S. Nakano; T. Kodaki; T. Mori

  第7回バイオ関連シンポジウム, 名古屋大学, 2013.9.27, 2013, Peer-reviewed

  
• Development of an artificial protein assembly on molecular switchboard by using DNA binding adaptors

  E. Nakata; T. Morii

  2013NNBS (New Trends of Nano- or Bio-materials Design in Supramolecular), Kyushu University, 2013.9.20, 2013, Peer-reviewed

  
• Construction of a molecular switchboard by using monomeric and homodimeric protein adaptors

  T.A. Ngo; E. Nakata; M. Saimura; S. Nakano; T. Kodaki; T. Morii

  Gordon Reseach Conforence, Proctor Academy Andover, NH, 2013.6.9-14, 2013, Peer-reviewed

  
• Development of latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives

  E. Nakata; T. Morii

  Gordon Reseach Conforence, Proctor Academy Andover, NH, 2013.6.9-14, 2013, Peer-reviewed

  
• 異なるアミノ酸配列のタウペプチド共存下での凝集体形成

  馬場あゆみ; 井上雅文; 今野卓; 仲野瞬; 中田栄司; 森井孝

  第7回バイオ関連シンポジウム, 名古屋大学, 2013.9.27, 2013, Peer-reviewed

  
• DNA origami上に機能性タンパク質を固定化した分子スイッチボードの開発

  中田栄司; Ngo Tien Anh; 仲野瞬; 才村正幸; 小瀧努; 森井孝

  第7回バイオ関連シンポジウム, 名古屋大学, 2013.9.27, 2013, Peer-reviewed

  
• アダプターを用いたDNAオリガミへのタンパク質１分子配置

  森井孝; 中田栄司; 仲野瞬

  ＣＲＥＳＴ「プロセスインテグレーションに向けた高機能ナノ構造体の創出」領域 第３回シンポジウム, 東京都, 2013.6.4, 2013, Peer-reviewed

  
• Development of self-assembled fluorescent nano probe based on asymmetric xanthene scaffold for detecting enzymatic activity

  E. Nakata; T. Morii

  The 4th Taiwan-Japan Symposium on Nanomedicine，Taiwan，2013.1.13-14, 2013, Peer-reviewed

  
• Enzymatic activatable fluorescent nano-probe

  E. Nakata; T. Morii

  Internaitonal Symposium on Nanomedicine Molecular Science，Kobe，2013.3.10, 2013, Peer-reviewed

  
• 自己集合型蛍光ナノプローブの細胞内動態の評価

  中田栄司; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• リボヌクレオペプチドリセプターを用いたナノ集成体の構築

  劉芳芳; C. Annoni; 田村友樹; 仲野瞬; 中田栄司; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• 量体タンパク質を分子スイッチボードに配置するアダプターの開発

  T.A. Ngo; 中田栄司; 才村正幸; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• 種類のタウタンパク質凝集性ペプチドによるアミロイド繊維形成の評価

  馬場あゆみ; 井上雅文; 今野卓; 仲野瞬; 中田栄司; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• 亜鉛フィンガータンパク質を用いたDNAオリガミへのタンパク質1分子固定化技術の開発

  西口泰裕; 中田栄司; 上村昇平; N.A. Tien; 才村正幸; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• 反応活性中心を導入したリボヌクレオペプチド

  田村友樹; 藤川祐典; 仲野瞬; 中田栄司; 森井孝

  日本化学会第93春季年会，草津市，2013.3.22-25, 2013, Peer-reviewed

  
• 体のなかにある分子コンビナート

  森井孝

  第32回品川セミナー，京都大学東京オフィス，2013.1.11, 2013, Peer-reviewed

  
• Construction of ratiometric fluorescent sensors by ribonucleopeptides

  Chiara Annoni; Eiji Nakata; Tomoki Tamura; Fong Fong Liew; Shun Nakano; Maria Luisa Gelmi; Takashi Morii

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, Peer-reviewed, Invited

  
• DNA-binding Proteins as the Adaptor for Locating Functional Proteins on DNA Nanostructure

  T.A. Ngo; 中田栄司; 森井孝

  第59回日本生化学会近畿支部例会，京都大学宇治キャンパス，2012.5.19, 2012, Peer-reviewed

  
• Deverlopment of an Adaptor for Locating Functional Proteins on DNA Nanoarchitechtures

  T.A. Ngo; E. Nakata; T. Morii

  The 4th International Symposium of Kyoto University Global COE Program，Thailand，2012.5.22-23, 2012, Peer-reviewed

  
• アダプターを用いたDNAオリガミへのタンパク質1分子配置

  中田栄司; 森井孝

  「プロセスインテグレーションによる次世代ナノシステムの創製」3領域合同会議，東京，2012.10.5, 2012, Peer-reviewed

  
• 自己集合型蛍光ナノプローブによる細胞内酵素反応のリアルタイム検出

  中田栄司; 森井孝

  ナノメディシン分子科学若手の会，名古屋市，2012.9.23, 2012, Peer-reviewed

  
• アダプターを用いたDNAオリガミへのタンパク質配置

  中田栄司; 森井孝

  「ナノ構造体」第2回公開シンポジ ウム，東京，2012.6.12, 2012, Peer-reviewed

  
• RNA–ペプチド複合体を基本骨格とした蛍光性バイオセンサーの合理的設計法の開発

  田村友樹; 劉芳芳; 仲野瞬; 中田栄司; 森井孝

  第59回日本生化学会近畿支部例会，京都大学宇治キャンパス，2012.5.19, 2012, Peer-reviewed

  
• RNAアプタマーを用いた機能性リボヌクレオペプチドの段階的構築

  田村友樹; 仲野瞬; 中田栄司; 森井孝

  日本化学会第92春季年会，慶応大学日吉キャンパス・矢上キャンパス，2012.3.25-28, 2012, Peer-reviewed

  
• Zinc Finger protein を介したDNA origami上への機能性タンパク質の配置

  西口泰裕; Liew Fong Fong; 中田栄司; 森井孝

  日本化学会第92春季年会，慶応大学日吉キャンパス・矢上キャンパス，2012.3.25-28, 2012, Peer-reviewed

  
• 準安定複合体を利用したRNA検出蛍光プローブの開発

  松本桂彦; 中田栄司; 森井孝

  日本化学会第92 春季年会，慶応大学日吉キャンパス・矢上キャンパス，2012.3.25-28, 2012, Peer-reviewed

  
• タウタンパク質由来の凝集性ペプチドによるアミロイド線維形成能の評価

  中田栄司; 吉田裕生; 井上雅文; 今野卓; 森井孝

  日本化学会第92春季年会，慶応大学日吉キャンパス・矢上キャンパス，2012.3.25-28, 2012, Peer-reviewed

  
• 細胞内シグナル分子を可視化する

  森井孝

  アゴラ・サノフィ，京都大学時計台記念館，2012.1.25, 2012, Peer-reviewed

  
• 【がん放射線治療の現状と今後に向けて:総説】 がんの特異的な検出を目指した蛍光イメージング法の最近の展開

  中田 栄司; 森井 孝; 宇都 義浩; 堀 均

  放射線生物研究, Sep. 2011

  
• オボアルブミンにおけるアミロイド形成コアの探索

  高橋延行; 森本祐未; 和久友則; 多田朋子; 野口由里香; 森井孝; 今野卓; 三上文三; 田中直毅

  日本農芸化学会大会講演要旨集, 05 Mar. 2011, Peer-reviewed

  
• A Modular Strategy for Tailoring Functional Ribonucleopeptides

  T. Morii

  Bioorganic Chemistry Gordon Research Conference，USA，2011.6.13, 2011, Peer-reviewed

  
• Toward of a photoinduced oxidase by using the electric charge transportation through DNA

  K. Matsumoto; T. Morii

  FIBER International Symposium FIBER Forum 2011，Hyogo，2011.11.6-8, 2011, Peer-reviewed

  
• Sequence selective RNA detection by metastable PNA/RNA fluorescence probe

  K. Matsumoto; E. Nakata; I. Saito; T. Morii

  The 38th International Symposium on Nucleic Acid Chemistry，Hokkaido，2011.11.9-11, 2011, Peer-reviewed

  
• Facile conversion of RNA aptamers to modular fluorescent sensors

  T. Tamura; S. Nakano; E. Nakata; T. Morii

  The 38th International Symposium on Nucleic Acid Chemistry，Hokkaido，2011.11.9-11, 2011, Peer-reviewed

  
• Development of the immobilization technology of functional proteins on DNA origami

  E. Nakata; C. Uwatoko; F.F. Liew; S. Kiyonaka; Y. Mori; Y. Katsuta; M. Endo; H. Sugiyama; T. Morii

  The 38th International Symposium on Nucleic Acid Chemistry，Hokkaido，2011.11.9-11, 2011, Peer-reviewed

  
• Development of the attachment technology of functional proteins on DNA origami

  A. Ngo; E. Nakata; F.F. Liew; Y. Nishiguchi; T. Morii

  11th iCeMS International Symposium，Kyoto，2011.12.6, 2011, Peer-reviewed

  
• タウタンパク質凝集コアペプチドのアミロイド線維形成能の評価

  中田栄司; 開田真次; 中川勝統; 今野卓; 森井孝

  日本化学会第91春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• DNA origami上への機能性タンパク質固定化技術の開発

  中田栄司; 上床知佐奈; 劉芳芳; 清中茂樹; 森泰生; 勝田陽介; 遠藤政幸; 杉山弘; 森井孝

  第5回バイオ関連化学シンポジウム，つくば国際会議場「エポカルつくば」，2011.9.12-14, 2011, Peer-reviewed

  
• 準安定二重鎖を用いたRNA配列認識PNA蛍光センサー

  松本桂彦; 中田栄司; 森井孝

  第5回バイオ関連化学シンポジウム，つくば国際会議場「エポカルつくば」，2011.9.12-14, 2011, Peer-reviewed

  
• 高い配列認識能をもつPNA 蛍光センサーによるRNA検出

  松本桂彦; 中田栄司; 森井孝

  生体関連化学部会第26 回若手フォーラム，筑波大学，2011.9.11, 2011, Peer-reviewed

  
• 高いDNA/RNA配列認識能を有するPNA蛍光センサー

  松本桂彦; 中田栄司; 森井孝

  生体関連化学部会若手の会第23回サマースクール，広島，2011.7.22-23, 2011, Peer-reviewed

  
• NA ナノ構造体への機能性分子修飾による新規機能性材料の開発

  西口泰裕; 中田栄司; 森井孝

  生体関連化学部会若手の会第23回サマースクール，広島，2011.7.22-23, 2011, Peer-reviewed

  
• RNPを用いたモジュール型蛍光センサーの作製

  田村友樹; 仲野瞬; 中田栄司; 森井孝

  生体関連化学部会若手の会第23回サマースクール，広島，2011.7.22-23, 2011, Peer-reviewed

  
• 細胞内pH計測用自己集合型蛍光プローブ

  中田栄司; 森井孝

  グローバルCOE「地球温暖化時代のエネルギー科学拠点」産学連携シンポジウム，京都テルサテルサホール，2011.12.15, 2011, Peer-reviewed

  
• 細胞内シグナル伝達分子を可視化するケミカルバイオロジ ・ツール

  森井孝

  本大学大学院薬学研究科，熊本大学大学院薬学研究科，2011.11.25, 2011, Peer-reviewed

  
• 生物がエネルギーを利用するためのしかけを考える

  森井孝

  京都大学エネルギー理工学研究所公開講演会「ゼロエミッションエネルギーって何だろう?」，きはだホール，2011.5.14, 2011, Peer-reviewed

  
• 卵白アルブミンのアミロイドコア領域の同定と線維形成機構

  河内悠希; 森本祐未; 高橋延行; 森井孝; 和久友則; 功刀滋; 田中直毅

  日本化学会第91春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• 光合成アンテナタンパク質集合体の脂質膜中での構築とそのエネルギー移動評価

  渡部奈津子; 角野歩; 佐々木伸明; 出羽毅久; 森井孝; 橋本秀樹; 南後守

  日本化学会第91春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• DNA origami上への機能性分子固定化技術の開発

  上床知佐奈; 李紅梅; 田井中一貴; 中田栄司; 森井孝

  日本化学会第91春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• ATP結合性リボヌクレオペプチドリセプターの合理的機能改変

  仲野瞬; 中田栄司; 森井孝

  日本化学会第91 春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• 蛍光センサーによる単一細胞内イノシトールポリリン酸代謝動態の解析

  森井孝

  日本化学会第91春季年会，神奈川大学横浜キャンパス，2011.3.26-29, 2011, Peer-reviewed

  
• 第6章機能性RNA-タンパク質複合体

  森井孝

  核酸化学のニュートレンド DNA/RNAの新たな可能性を拓く，2011, 2011, Peer-reviewed

  
• Structural aspects of the fluorescence intensity changes of the ATP-binding ribonucleopeptide sensor

  Nakano, S; Mashima, T; Tainaka, K; Katahira, M; Morii, T

  The 37th International Symposium on Nucleic Acids Chemistry 2010,, Nov. 2010

  
• 生存基盤科学における中赤外域波長可変レーザーの先進応用

  紀井俊輝; 大垣英明; 上杉志成; 森井孝; 山本浩平; 鈴木義和; 増田開

  京都大学生存基盤科学研究ユニット研究成果報告書, 10 Sep. 2010

  
• Selective Detection of Cellular Signaling Molecules

  T. Morii

  1st Asian Chemical Biology Conference, Seoul National University, 2010.6.27, 2010, Peer-reviewed

  
• Analyses of the structure and the function of ribonucleopeptidereceptors: toward the construction of the novel ribbonucleopeptide enzyme

  S. Nakano; K. Tainaka; T. Morii

  The 2nd International Symposium Kyoto University Global COE Program, Uji, 2010.8.19-20, 2010, Peer-reviewed

  
• Construction of functional ribonucleopeptide (RNP) Complex for Catecholamine Detection

  F.F. Liew; K. Tainaka; S. Nakano; T. Morii

  The 2nd International Symposium Kyoto University Global COE Program, Uji,2010.8.19-20, 2010, Peer-reviewed

  
• Design and synthesis of fluorescent oligodeoxyribonucleotides sensitive to the micro environmental change in polarity

  K. Matsumoto; Y. Saito; T. Morii; I. Saito

  The 2nd International Symposium Kyoto University Global COE Program, Uji, 2010.8.19-20, 2010, Peer-reviewed

  
• Assembly of biological macromolecules on DNA nanostructures

  H. Li; C. Uwatoko; K. Tainaka; T. Morii

  The 2nd International Symposium Kyoto University Global COE Program, Uji, 2010.8.19-20, 2010, Peer-reviewed

  
• A Modular Strategy for Tailoring Fluorescent Biosensors from Ribonucleopeptides

  T. Morii

  Asian 3 Roundtabe on Nucleic Acids, Kansai International Airport Conference Hall, 2010.10.29, 2010, Peer-reviewed

  
• A Charge-Pairing Mechanism on Amyroid Fibrillation of Short Core Peptides From Human Tau Protein.,

  K. Nakagawa; S. Kaida; M. Inoue; K. Tainaka; T. Konno; E. Nakata; T. Morii

  International Symposium of Advanced Energy Science, Uji, 2010.11.18-19, 2010, Peer-reviewed

  
• A facile strategy for improvement of selectivity and fluorescence responses of dopamine-binding ribonucleopeptide sensors

  F.F. Liew; K. Tainaka; T. Morii

  International Symposium of Advanced Energy Science, Uji, 2010.11.18-19, 2010, Peer-reviewed

  
• Structural aspects for substrate binding and fluorescence of the ATP-binding ribonucleopeptide receptors and sensors

  S. Nakano; M. Fukuda; T. Mashima; M. Katahira; T. Morii

  5th International Peptide Symposium in conjunction with 47th Japanese Peptide Symposium, Kyoto, 2010.12.4-9, 2010, Peer-reviewed

  
• A Charge-Pairing Mechanism on Amyroid Fibrillation of Human Tau Protein Related Peptides

  K. Nakagawa; S. Kaida; M. Inoue; K. Tainaka; T. Konno; E. Nakata; T. Morii

  5th International Peptide Symposium in conjunction with 47th Japanese Peptide Symposium, Kyoto, 2010.12.4-9, 2010, Peer-reviewed

  
• 細胞内シグナル分子を標的とした蛍光センサーの構築

  T. Morii

  第5回ケミカルバイオロジー・第2回センシングバイオロジーシンポジウム，東京医科歯科大学医学部，2010.2.23, 2010, Peer-reviewed

  
• 極性環境変化に敏感な蛍光性核酸塩基を用いた遺伝子検出プローブ

  松本桂彦; 森井孝; 齋藤義雄; 齋藤烈

  日本光医学・光生物学会, 2010, Peer-reviewed

  
• オボアルブミンのアミロイド線維形成：内在性ペプチドの添加効果

  高橋延行; 野口由里香; 富永祥太; 長谷川哲也; 森井孝; 三上文三; 田中直毅

  日本農芸化学会大会講演要旨集, 05 Mar. 2009, Peer-reviewed

  
• Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

  Shigeki Kiyonaka; Kenta Kato; Motohiro Nishida; Kazuhiro Mio; Takuro Numaga; Yuichi Sawaguchi; Takashi Yoshida; Minoru Wakamori; Emiko Mori; Tomohiro Numata; Masakazu Ishii; Hiroki Takemoto; Akio Ojida; Kenta Watanabe; Aya Uemura; Hitoshi Kurose; Takashi Morii; Tsutomu Kobayashi; Yoji Sato; Chikara Sato; Itaru Hamachi; Yasuo Mori

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2009, Peer-reviewed

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• Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

  Shigeki Kiyonaka; Kenta Kato; Motohiro Nishida; Kazuhiro Mio; Takuro Numaga; Yuichi Sawaguchi; Takashi Yoshida; Minoru Wakamori; Emiko Mori; Tomohiro Numata; Masakazu Ishii; Hiroki Takemoto; Akio Ojida; Kenta Watanabe; Aya Uemura; Hitoshi Kurose; Takashi Morii; Tsutomu Kobayashi; Yoji Sato; Chikara Sato; Itaru Hamachi; Yasuo Mori

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2009, Peer-reviewed

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• 蛍光タンパク質をもとにしたイノシトール四リン酸センサーの設計

  藤枝伸宇; 山本誠吾; 遠藤太志; 坂口怜子; 田井中一貴; 森井孝

  日本化学会第89春季年会，日本大学，2009.3.27-30, 2009, Peer-reviewed

  
• リボヌクレオペプチド複合体による蛍光センサーの設計

  森井孝

  第58回高分子討論会，熊本大学黒髪南キャンパス，2009.9.16-18, 2009, Peer-reviewed

  
• 遺伝子検出の為のための画期的なモレキュラービーコンの開発

  松本桂彦; 篠原雄太; 竹内辰樹; 齋藤義雄; 齋藤烈; 森井孝

  第24回生体機能関連化学シンポジウム・第12回バイオテクノロジー部会シンポジウム，九州大学医系キャンパス，2009.9.13-15, 2009, Peer-reviewed

  
• ATP結合性リボヌクレオペプチドリセプターの機能と構造

  仲野瞬; 福田将虎; 真嶋司; 片平正人; 森井孝

  第24回生体機能関連化学シンポジウム・第12回バイオテクノロジー部会シンポジウム，九州大学医系キャンパス，2009.9.13-15, 2009, Peer-reviewed

  
• 可視光照射により光電流応答を示すDNA自己組織化膜の作製

  丹佳夫; 田井中一貴; 藤枝伸宇; 森井孝

  日本化学会第89春季年会，日本大学，2009.3.27-30, 2009, Peer-reviewed

  
• 蛍光性リボヌクレオペプチドセンサーの機能と構造の相関

  仲野瞬; 福田将虎; 田井中一貴; 森井孝

  日本化学会第89春季年会，日本大学，2009.3.27-30, 2009, Peer-reviewed

  
• タウタンパク質凝集コアのリン酸化によるアミロイド繊維形成制御

  井上雅文; 田井中一貴; 今野卓; 森井孝

  日本化学会第89春季年会，日本大学，2009.3.27-30, 2009, Peer-reviewed

  
• 森井孝，生理活性アミンを検出する蛍光性リボヌクレオペプチドセンサーの構築方法

  福田将虎; 長谷川哲也; FongFong Liew; 森井孝

  日本化学会第89春季年会，日本大学，2009.3.27-30, 2009, Peer-reviewed

  
• Design of extremely facile 3\\'- and 5\\'- ends free molecular beacons using C8 alkylamino substituted 2\\'-deoxyguanosine.

  K. Matsumoto; Y. Shinohara; K. Numajiri; S. Ishioroshi; T. Morii; Y. Saito; I. Saito

  Nucleic acids symposium series (2004), 2009, Peer-reviewed

  
• Covalently linked fluorescent ribonucreopeptide sensors.

  M. Fukuda; L. Fong-Fong; T. Morii

  Nucleic acids symposium series (2004), 2009, Peer-reviewed

  
• Structural aspects for the function of ATP-binding ribonucleopeptide receptors.

  S. Nakano; M. Fukuda; T. Mashima; M. Katahira; T. Morii

  Nucleic acids symposium series (2004), 2009, Peer-reviewed

  
• Structural analysis of ribonucleopeptide aptamer against ATP.

  T. Mashima; A. Matsugami; S. Nakano; M. Inoue; M. Fukuda; T. Morii; M. Katahira

  Nucleic acids symposium series (2004), 2009, Peer-reviewed

  
• A pyrazole compound selectively inhibits receptor activated TRPC3 channel

  Kenta Kato; Shigeki Kiyonaka; Motohiro Nishida; Masakazu Ishii; Emiko Mori; Takuro Numaga; Takashi Yoshida; Takafumi Miki; Tsutomu Kobayashi; Takashi Morii; Itaru Harnachi; Minoru Wakamori; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008

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• The amyloid fibrillization of phosphorylated human tau core peptides

  M Inoue; K Tainaka; T Konno; T Morii

  The IUMRS International Conference in Asia 2008, 名古屋国際会議場, 2008.12.9-13, 2008, Peer-reviewed

  
• タウタンパク質凝集性コアペプチドのアミロイド繊維形成におけるリン酸化の効果

  井上雅文; 平田晃義; 今野卓; 森井孝

  第3回バイオ関連化学合同シンポジウム，東京工業大学，2008.9.18-20, 2008, Peer-reviewed

  
• 共有結合により安定化した機能性RNA-ペプチド複合体の構築方法

  福田将虎; 仲野瞬; 田井中一貴; 森井孝

  第10回RNAミーティング，札幌コンベンションセンター，2008.7.23-25, 2008, Peer-reviewed

  
• 最小構造からなる単量体メタン水酸化酵素の分子設計（2）

  龍山裕一; 藤枝伸宇; 井上雅文; 森井孝

  日本化学会第88春季年会，立教大学池袋キャンパスおよび立教池袋中学校・高等学校，2008.3.26-30, 2008, Peer-reviewed

  
• 蛍光性バイオセンサーによるイノシトール四リン酸細胞内動態の計測

  坂口怜子; 清中茂樹; 森泰生; 森井孝

  日本化学会第88春季年会，立教大学池袋キャンパスおよび立教池袋中学校・高等学校，2008.3.26-30, 2008, Peer-reviewed

  
• 共有結合によって安定化した蛍光性リボヌクレオペプチドセンサー

  福田将虎; 森井孝

  日本化学会第88春季年会，立教大学池袋キャンパスおよび立教池袋中学校・高等学校，2008.3.26-30, 2008, Peer-reviewed

  
• 生体シグナル伝達分子を標的とした蛍光バイオセンサーの創製

  森井孝; 長谷川哲也; 林宏典

  第5回ライフサーベイヤシンポジウム，名古屋大学野依記念学術交流会館，2008.1.31-2.1, 2008, Peer-reviewed

  
• Selective recognition of a tetra-amino-acid motif containing phosphorylated tyrosine residue by ribonucleopeptide.

  S. Nakano; T. Hasegawa; M. Fukuda; N. Fujieda; K. Tainaka; T. Morii

  Nucleic acids symposium series (2004), 2008, Peer-reviewed

  
• Development of ribonucleopeptide-based fluorescent sensors for biologically active amines based on the stepwise molding strategy.

  K. Tainaka; T. Hasegawa; M. Fukuda; S. Nakano; N. Fujieda; T. Morii

  Nucleic acids symposium series (2004), 2008, Peer-reviewed

  
• Construction of a stable functional ribonucleopeptide complex by the covalent linking method.

  M. Fukuda; S. Nakano; K. Tainaka; N. Fujieda; T. Morii

  Nucleic acids symposium series (2004), 2008, Peer-reviewed

  
• 3P050 Effects of chemical modification upon aggregation properties of tau-derived peptides(Proteins-stability, folding, and other physicochemical properties,Poster Presentations)

  Konno Takashi; Hirata Akiyoshi; Sugimoto Kennji; Morii Takashi

  Biophysics, 20 Nov. 2007

  
• A novel pyrazole derivative selectively inhibits TRPC3 channel.

  Kenta Kato; Shigeki Kiyonaka; Motohiro Nishida; Masakazu Ishi; Emiko Mori; Takuro Numaga; Takashi Yoshida; Takafumi Miki; Tsutomu Kobayashi; Takashi Morii; Itaru Hamachi; Minoru Wakamori; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007

  
• Design of Ribonucleopeptide-Based Fluorescent Biosensors for Phosphorylated Tyrosine Residues

  H Hayashi; T Hasegawa; T Morii

  The 2nd International workshop on Approaches to single-cell Analysis, 早稲田大学，井深大記念館，2007.9.6-7, 2007, Peer-reviewed

  
• Construction of Fluorescent Sensors to Quantitatively Assess Inositol Tetrakisphosphate (IP4) in Single Cell

  R Sakaguchi; K Sugimoto; S Kiyonaka; Y Mori; T Morii

  The 2nd International workshop on Approaches to single-cell Analysis, 早稲田大学，井深大記念館，2007.9.6-7, 2007, Peer-reviewed

  
• Structure-based design of fluorescent biosensors from ribonucleopeptide complexes

  H Hayashi; M Inoue; T Morii

  第5回国際核酸化学シンポジウム，東京大学，安田講堂 2007.11.20-22, 2007, Peer-reviewed

  
• リボヌクレオペプチドを用いた蛍光性バイオセンサーの設計

  林宏典; 井上雅文; 森井孝

  第9回RNAミーティング，名古屋国際会議場，2007.7.28-31, 2007, Peer-reviewed

  
• 中赤外域波長可変レーザーの生存基盤科学へのフィージビリティスタディ

  大垣英明; 上杉志成; 森井孝; 山本浩平; 鈴木義和; 山崎鉄夫; 増田開; 紀井俊輝

  第13回FELとHigh-Power Radiation研究会，京都大学宇治キャンパス木質ホール3F，2007.3.5-6, 2007, Peer-reviewed

  
• 単量体メタン水酸化酵素の分子設計

  藤枝伸宇; 井上雅文; 龍山裕一; 森井孝

  BMB2007（第30回日本分子生物学会年会・第80回日本生化学界大会合同大会），パシフィコ横浜，2007.12.11-15, 2007, Peer-reviewed

  
• 立体構造にもとづいたミニチュアメタン水酸化酵素の分子設計

  藤枝伸宇; 井上雅文; 森井孝

  第22回生体機能関連化学シンポジウム，東北大学，多元物質科学研究所，2007.9.28-29, 2007, Peer-reviewed

  
• 細胞内情報伝達経路の可視化を目指した蛍光分子センサーの開発

  坂口怜子; 杉本健二; 清中茂樹; 森泰生; 森井孝

  第22回生体機能関連化学シンポジウム，東北大学，多元物質科学研究所，2007.9.28-29, 2007, Peer-reviewed

  
• 生理活性アミンを標的とする傾向性リボヌクレオペプチドセンサーの開発

  福田将虎; 仲野瞬; 森井孝

  第22回生体機能関連化学シンポジウム，東北大学，多元物質科学研究所，2007.9.28-29, 2007, Peer-reviewed

  
• タンパク質と核酸で機能性分子をつくる

  森井孝

  化学プラットフォーム＠関西07講演会，兵庫県立大学，書写キャンパス，2007.9.15, 2007, Peer-reviewed

  
• 機能性RNAペプチド複合体の構築

  森井孝

  日本薬学会北陸支部特別講演会，富山大学，杉谷キャンパス，2007.5.18, 2007, Peer-reviewed

  
• Controlling a substrate-binding geometry of ribonucleopeptide receptor.

  M. Fukuda; S. Nakano; T. Morii

  Nucleic acids symposium series (2004), 2007, Peer-reviewed

  
• Real time fluorescent sensors to assess in vivo inositol polyphosphates productions

  T. Morii

  A Satellite Meeting of International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting，Graduate School of Pharmaceutical Sciences, Kyoto University，2006.11.10-11, 10 Nov. 2006, Peer-reviewed

  
• Amyloid-Type Fibril Formation of a Short Peptide with a Chemically Modified Tyrosine Residue

  A. Hirata; T. Morii; T. Konno

  International Conference 43rd Japanese Peptide Symposium/4th Peptide Engineering Meeting，Pacifico Yokohama (Annex Hall)，2006.11.5-8, 2006, Peer-reviewed

  
• Stepwise Functionalization of Ribonucleopeptides

  T. Hasegawa; M. Fukuda; T. Morii

  International Conference 43rd Japanese Peptide Symposium/4th Peptide Engineering Meeting，Pacifico Yokohama (Annex Hall)，2006.11.5-8, 2006, Peer-reviewed

  
• Design of functional miniature proteins

  T. Morii

  2nd Kyoto-Erlangen Symposium，Uji Campus, Kyoto University，2006. 10.3-5, 2006, Peer-reviewed

  
• Structure-based design of miniature methane monooxygenase hydroxylase

  M. Inoue; Y. Tatuyama; K. Sugimoto; T. Morii

  The 3rd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto，2006.8.30-9.1, 2006, Peer-reviewed

  
• Construction of protein-based optical sensor to quantitatively assess inositol tetrakisphosphate

  R. Sakaguchi; S. Kiyonaka; K. Sugimoto; Y. Mori; T. Morii

  The 3rd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto，2006.8.30-9.1, 2006, Peer-reviewed

  
• Reforming of Biomass-derived CO2 by composite Iron with Nickel and/or copper

  T. Sagawa; J. Takahashi; T. Morii

  The 3rd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto，2006.8.30-9.1, 2006, Peer-reviewed

  
• Interfacial Electron-Transfer Processes in Colloidal TiO2 and Poly(octadecyl acrylate)s Systems

  T. Sagawa; S. Uchida; J. H.G. Steinke; R. Oda; H. Ihara; T. Morii

  Gordon Research Conference on Chemistry at Interfaces 2006，University of New England, Biddeford, ME, U.S.A.，2006.7.9-14, 2006, Peer-reviewed

  
• Interfacial Electron-Transfer Processes with Molecular Imprinted TiO2

  T. Sagawa; M. Kudo; J. HG Steinke; T. Morii

  XXIst IUPAC SYMPOSIUM ON PHOTOCHEMISTRY，京都テルサ（京都），2006.4.2-7, 2006, Peer-reviewed

  
• Surface molecularly imprinted TiO₂ nanoparticle for photoreduction of viologen

  T. Sagawa; M. Kudo; J.H.G. Steinke; T. Morii

  Materials Research Society Symposium Proceedings, 2006, Peer-reviewed

  
• ペプチドライブラリーを用いたリボヌクレオペプチドリセプターの段階的高機能化

  福田将虎; 森井孝

  バイオ関連化学合同シンポジウム（生体機能関連化学部会（21回）バイオテクノロジー部会（9回）生命化学研究会（9回）），京都大学工学研究科（桂キャンパス），2006.9.28-30, 2006, Peer-reviewed

  
• 機能性リボヌクレオペプチドリセプターによるケミカルバイオロジーへのアプローチ

  森井孝

  SORST齋藤チームシンポジウム「ゲノム化学の最先端ー医学・分子生物学への応用と展開」，日本大学工学部50周年記念館講堂，2006.9.28-30, 2006, Peer-reviewed

  
• 凝集性短鎖ペプチドを用いた複合材料の作製

  藤本菜保; 平田晃義; 森井孝; 佐川尚

  第52回高分子研究発表会（神戸），兵庫県中央労働センター（神戸），2006.7.21, 2006, Peer-reviewed

  
• 酸化チタン／ポリマー交互積層膜の作製とその光触媒作用

  佐川尚; 森井孝

  第52回高分子研究発表会（神戸），兵庫県中央労働センター（神戸），2006.7.21, 2006, Peer-reviewed

  
• シラフィンモデルペプチドの凝集状態の解析と複合材料の開発

  藤本菜保; 平田晃義; 森井孝; 佐川尚

  第55回高分子学会年次大会，名古屋国際会議場（名古屋），2006.5.24-26, 2006, Peer-reviewed

  
• 蛋白質でセンサーをつくる〜機能性リボヌクレオペプチドの設計〜

  森井孝

  日本ケミカルバイオロジー研究会第1回年会，学術総合センター（東京），2006.5.8-9, 2006, Peer-reviewed

  
• 機能性ミニチュアタンパク質をツールとするケミカルバイオロジー

  森井孝

  21世紀COE「京都大学化学連携研究教育拠点」ケミカルバイオロジー・ミニシンポジウム一味違う化学と生命現象の接点を目指して，京都大学，2006.3.15, 2006, Peer-reviewed

  
• Ribonucleopeptides recognize the phosphotyrosine residue

  T. Hasegawa; S. Yoshikawa; T. Morii

  第4回国際核酸化学シンポジウム，九州大学(福岡)，2005.9.20-22, 2005, Peer-reviewed

  
• Toward the design of artificial enzymes for sutainable energy system: artificial methane monooxygenase assembly

  T. Morii

  Core University Program between Seoul National University and Kyoto University on Energy Science & Engineering, Korea-Japan Joint Mini Symposium，京都大学，2005.7.25, 2005, Peer-reviewed

  
• Ribonucleopeptide Receptors for phosphotyrosine

  T. Hasegawa; T. Morii

  Gordon Research Conference Bioorganic Chemistry，Proctor Academy (アメリカ)，2005.6.12-17, 2005, Peer-reviewed

  
• Stepwise functionalization of ribonucleopeptide complexes to receptors and sensors.

  M. Fukuda; Y. Tanabe; T. Morii

  Nucleic acids symposium series (2004), 2005, Peer-reviewed

  
• 機能性ミニチュアタンパク質によるケミカルバイオロジーへのアプローチ

  森井孝

  平成17年度中部化学関係学協会支部連合秋季大会，2005.9.24, 2005, Peer-reviewed

  
• イノシトール四リン酸に対する蛍光性バイオセンサーの構築

  坂口怜子; 杉本健二; 沼賀拓郎; 清中茂樹; 森泰生; 大久保捷敏; 森井孝

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• リボヌクレオペプチドの機能化

  森井孝

  第4回SORSTジョイントシンポジウム，2005.11.29, 2005, Peer-reviewed

  
• イノシトール四リン酸バイオセンサーの細胞への応用

  坂口怜子; 森井孝

  JST・SORSTジョイントシンポジウム(4)，千里ライフサイエンスセンター(大阪)，2005.11.28-29, 2005, Peer-reviewed

  
• リン酸化チロシンを標的とするリボヌクレオペプチドリセプターおよびセンサーの開発

  長谷川哲也; 森井孝

  JST・SORSTジョイントシンポジウム(4)，千里ライフサイエンスセンター(大阪)，2005.11.28-29, 2005, Peer-reviewed

  
• 病理的タンパク質凝集の促進に関わる環境分子間の非線形的協同の一例

  今野卓; 森井孝; 老木成稔

  第43回生物物理学会年会，仙台（宮城），2005.11.24, 2005, Peer-reviewed

  
• 思い通りに測れる蛍光バイオセンサー

  森井孝

  京都バイオ産業技術フォーラム第6回研究会，2005.11.9, 2005, Peer-reviewed

  
• 分子の認識から機能の設計へ

  森井孝

  第7回脳分子機能研究会，2005.11.5, 2005, Peer-reviewed

  
• Development of a Nanobiodevice based Ribonucleopeptide Complex

  T. Hasegawa; M. Hagihara; S. Sato; K. Ohkubo; T. Morii; S. Yoshikawa

  The 2nd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto (Japan)，2004.12.17-18, 17 Dec. 2004, Peer-reviewed

  
• Biomass-derived Carbon Recycle System with Composite Iron Catalyst

  G. Kozen; Y. Fujii; T. Sagawa; T. Morii; K. Ohkubo

  The 2nd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto, Japan，2004.12.17-18, 17 Dec. 2004, Peer-reviewed

  
• Production of Methane, Methanol by Supercritical Water Technology - Biomethanol Production from Biomethane

  T. Morii; T. Sagawa; Y. Fujii; K. Ohkubo

  The 2nd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto, Japan，2004.12.17-18, 17 Dec. 2004, Peer-reviewed

  
• Development of specific DNA binding nanobiodevice by combinatorial approach

  A. Hirata; T. Morii; K. Ohkubo; S. Yoshikawa

  The 2nd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto (Japan)，2004.12.17-18, 17 Dec. 2004, Peer-reviewed

  
• Design of biosensors and receptors from a small protein assembly

  T. Morii; K. Sugimoto; R. Sakaguchi; K. Ohkubo

  International symposium on Nano-organization and Function，Tokyo，2004.11.11-12, 11 Nov. 2004, Peer-reviewed

  
• Tailoring receptors and sensors from an RNA-peptide assmebly

  Y. Tanabe; M. Hagihara; S. Sato; K. Ohkubo; T. Morii

  International symposium on Nano-organization and Function，Tokyo，2004.11.11-12, 11 Nov. 2004, Peer-reviewed

  
• Toward a development of an enzymatic system for biomass utilization: Strategy to construct a functional methane monooxygenase

  R. Sakaguchi; Y. Fujii; T. Morii; K. Ohkubo

  The joint international conference on "Sustainable Energy and Environment (SEE)"，Hua Hin, Thailand，2004.12.1-3, 2004, Peer-reviewed

  
• Design of sensing ribonucleopeptides for small ligands.

  M. Hagihara; T. Hasegawa; Y. Tanabe; S. Sato; S. Yoshikawa; K. Ohkubo; T. Morii

  Nucleic acids symposium series (2004), 2004, Peer-reviewed

  
• Toward a development of an enzymatic system that converts biomass to biomethanol: Design of a tailor-made reductase for an artificial methane monooxygenase assembly

  Y. Tanabe; T. Morii; K. Ohkubo

  The joint international conference on "Sustainable Energy and Environment (SEE)"，Hua Hin, Thailand，2004.12.1-3, 2004, Peer-reviewed

  
• テーラーメイドバイオセンサーへのアプローチ

  森井孝

  福井大学大学院セミナー，2004.11.5, 2004, Peer-reviewed

  
• リボヌクレオペプチド複合体を利用した蛍光センサーの開発

  萩原正規; 田邊優貴子; 佐藤慎一; 長谷川哲也; 吉川暹; 大久保捷敏; 森井孝

  第19回生体機能関連化学シンポジウム，東京大学弥生講堂，2004.10.8-9, 2004, Peer-reviewed

  
• リセプターからセンサーへ：機能性分子設計によるケミカルバイオロジーへのアプローチ

  森井孝

  日本化学会生体関連化学部会、第16回生体関連化学サマースクール，2004.7.16, 2004, Peer-reviewed

  
• Design of sensing ribonucleopeptides for small ligands.

  M. Hagihara; T. Hasegawa; Y. Tanabe; S. Sato; S. Yoshikawa; K. Ohkubo; T. Morii

  Nucleic acids symposium series (2004), 2004, Peer-reviewed

  
• Recognition of Small Molecules by an RNA-peptide Complex

  HAGIHARA Masaki; SATO Shin-ichi; MORII Takashi; MAKINO Keisuke

  Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Feb. 2003

  
• Development of Catalytic Systems for the Biomass-derived Methanol Production and CO2 Reduction

  Yasuyo Fujii; Takashi Sagawa; Takashi Morii; Katsutoshi Ohkubo

  Kyoto University 21COE 2nd Symposium on Bioenergy，Organized by Kyoto University 21COE Program "Establishment of COE on Sustainable Energy System"，Kyoto, 2003, Peer-reviewed

  
• Design of a ribonucleopeptide biosensor

  Masaki Hagihara; Akiyoshi Hirata; Katsutoshi Ohkubo; Takashi Morii

  the 30th Nucleic Acids Chemistry Symposium，Sapporo, 2003, Peer-reviewed

  
• Ribonucleopeptide receptors

  T. Morii; K. Ohkubo; S. Yoshikawa

  18th American Peptide Symposium，Boston，USA, 2003, Peer-reviewed

  
• Biosensors to assess in vivo inositol 1,4,5-trisphosphate production

  Takashi Morii

  Gordon Research Conference on Bioorganic Chemistry，Andovor，USA, 2003, Peer-reviewed

  
• Design of phosphotyrosine-specific ribonucleopeptide receptors

  Tetsuya Hasegawa; Masaki Hagihara; Shin-ichi Sato; Takashi Morii; Katsutoshi Ohkubo; Susumu Yoshikawa

  The 1st International Symposium on Sustainable Energy System，Kyoto University 21COE Establishment of COE on Sustainable Energy System，Kyoto, 2003, Peer-reviewed

  
• New technologies for production of clean liquefied fuels: High-level expression of subunits of methane monooxygenase hydroxylase in E. coli

  Yasuyo Fujii; Masatora Fukuda; Takashi Sagawa; Takashi Morii; Katsutoshi Ohkubo

  The 1st International Symposium on Sustainable Energy System，Kyoto University 21COE Establishment of COE on Sustainable Energy System，Kyoto，, 2003, Peer-reviewed

  
• イノシトール四リン酸に対する分子センサーの構築

  本庄弘一; 杉本健二; 牧野圭祐; 大久保捷敏; 森井孝

  日本化学会第83春季年会，2003.3, 2003, Peer-reviewed

  
• DESIGN OF THE RIBONUCLEOPEPTIDE RECEPTORS

  T,Morii

  Gordon Research Conference: Chemistry & Biology of Peptides，VenturaUSA, 2002, Peer-reviewed

  
• 短鎖ペプチドによる認識DNA塩基配列の決定

  佐藤慎一; 本庄弘一; 辻晋司; 萩原正規; 牧野圭祐; 森井孝

  第29回核酸化学シンポジウム，2-P37，2002, 2002, Peer-reviewed

  
• DESIGN OF A FUNCTIONAL RNA-PEPTIDE COMPLEX

  T. Morii; M. Hagihara; K. Makino

  The International Conference on Fundamental Sciences: Chemical & Biological Sciences，Singapore, 2001, Peer-reviewed

  
• RNA・ペプチド複合体による人工リセプター（リボヌクレオペプチドリセプター）の創製

  萩原正規; 森井孝; 牧野圭祐

  第74回日本生化学会大会，4P-012，2001, 2001, Peer-reviewed

  
• bZIP構造によるDNA塩基配列特異的認識における構造転移の役割

  森井孝; 佐藤慎一; 牧野圭祐

  第74回日本生化学会大会，1P-195，2001, 2001, Peer-reviewed

  
• ロイシンジッパータンパク質によるDNA認識と構造転移の役割

  佐藤慎一; 何冬蘭; 森井孝; 牧野圭祐

  第16回生体機能関連化学シンポジウム，2001.9, 2001, Peer-reviewed

  
• NO induced novel DNA lesions: formation mechanism

  M. Yamada; T. Suzuki; K. Kanaori; K. Tajima; T. Morii; K. Makino

  第27回核酸化学シンポジウム，3-08, 2000, Peer-reviewed

  
• DNA binding of a basic leucine-zipper protein with novel folding domain.

  S. Sato; K. Makino; T. Morii

  Nucleic acids symposium series, 2000, Peer-reviewed

  
• In vitro selection by using mutated GCN4-bZIP peptides for analysis of peptide-DNA interactions.

  H. Furusawa; T. Morii; Y. Okahata

  Nucleic acids symposium series, 2000, Peer-reviewed

  
• “新しいDNA結合ドメインをもつロイシンジッパータンパク質によるDNA認識”

  佐藤慎一; 森井孝; 牧野圭祐

  第15回生体関連化学シンポジウム，2000.9, 2000, Peer-reviewed

  
• “塩基性領域を新しいドメインに改変したロイシンジッパータンパク質によるDNA認識”

  森井 孝; 佐藤 慎一; 牧野 圭祐

  蛋白合同年会東京2000年６月, 2000, Peer-reviewed

  
• “NO/O2系で生成する新規DNA傷害N2-ニトロデオキシグアノシン”

  山田真希; 鈴木利典; 金折賢二; 田嶋邦彦; 森井 孝; 牧野圭祐

  2000.5.13生化学会近畿支部 大阪市立大学, 2000, Peer-reviewed

  
• “NO/O2系で2’-デオキシグアノシンから生成するN2-ニトロ-2’-デオキシグアノシン”

  鈴木利典; 山田真希; 金折賢二; 田嶋邦彦; 森井孝; 牧野圭祐

  2000.3.29 日本化学会 千葉県・日本大学, 2000, Peer-reviewed

  
• 化学から見たタンパク質とDNAによる超分子複合体生成

  森井孝; 牧野圭祐

  第6回機能性ホストゲスト化学研究会，2000, 2000, Peer-reviewed

  
• RNA－ペプチド複合体による分子認識

  萩原正規; 森井孝; 牧野圭祐

  第15回生体機能関連化学シンポジウム，2000, 2000, Peer-reviewed

  
• 生体内セカンドメッセンジャーに対する分子センサーの構築

  杉本健二; 森井孝; 牧野圭祐; 森泰生; 井本敬二; 井上照彦; 杉浦幸雄; 大塚雅巳

  第15回生体機能関連化学シンポジウム，2000, 2000, Peer-reviewed

  
• "Formation of 8-Nitroguanine from 2'-Deoxyguanosine by NO/O2 System"

  Toshinori Suzuki; Masaki Yamada; Kenji Kanaori; Kunihiko Tajima; Takashi Morii; Keisuke Makino

  99.10核酸化学シンポジウム, 1999, Peer-reviewed

  
• Reactivity of 2\\'-deoxyoxanosine, a novel DNA lesion.

  T. Suzuki; M. Yamada; T. Ishida; T. Morii; K. Makino

  Nucleic acids symposium series, 1999, Peer-reviewed

  
• ”非共有結合ペプチド二量体による特異的ＤＮＡ塩基配列認識機構”

  相澤康則; 杉浦幸雄; 牧野圭祐; 森井 孝

  日本化学会第７６春季年会予稿集(1999)., 1999, Peer-reviewed

  
• ”オリゴペプチドによる協同的ＤＮＡ認識”

  森井 孝

  日本化学会第７６春季年会予稿集(1999), 1999, Peer-reviewed

  
• ”新規ＤＮＡ損傷デオキシオキザノシンの反応性”

  鈴木利典; 山田真希; 金折賢二; 田嶋邦彦; 森井孝; 牧野圭祐

  第７６回日本化学会第７５春季年会予稿集(1999), 1999, Peer-reviewed

  
• ”Cooperative DNA Binding by Short Peptides.”

  相沢康則; 森井孝; 杉浦幸雄

  第２５回核酸化学シンポジウム予稿集(1998)., 1998, Peer-reviewed

  
• ”オリゴペプチドによるＤＮＡ塩基配列の選択的分子認識”

  森井 孝

  機能性生体関連複合中分子研究会予稿集(1998), 1998, Peer-reviewed

  
• Selective recognition of tandemly repeated DNA sequences by homo- and heterodimers of short peptides.

  Y. Aizawa; T. Morii; Y. Sugiura

  Nucleic acids symposium series, 1997, Peer-reviewed

  
• “二量体ペプチドによるDNA認識：二量体形成部位の立体構造によるDNA塩基配列識別能の変化”

  岡上 雅子; 西明 芳隆; 牧野 圭祐; 森井 孝; 杉浦 幸雄

  第２３回核酸化学シンポジウム予稿集(1996), 1996, Peer-reviewed

  
• DNA recognition by peptide oligomers.

  J. Yamane; K. Makino; T. Morii; Y. Sugiura

  Nucleic acids symposium series, 1995, Peer-reviewed

  
• Sequence-specific DNA recognition by peptide heterodimers.

  M. Sawada; Y. Aizawa; M. Ueno; T. Morii; Y. Sugiura

  Nucleic acids symposium series, 1995, Peer-reviewed

  
• Mechanistic aspects of the interaction of antisense DNA.

  A. Murakami; Y. Tamura; S. Takeguchi; H. Miyoshi; T. Morii; T. Maekawa; T. Abe; K. Makino

  Nucleic acids symposium series, 1993, Peer-reviewed

  
• Loop-like structure of dGTTG in solution.

  K. Makino; M. Nishi; T. Suzuki; S. Ohsumi; T. Morii; H. Ide; A. Murakami

  Nucleic acids symposium series, 1993, Peer-reviewed

  
• NMR studies on solution structure of single-stranded oligonucleotides causing line broadening.

  A. Murakami; T. Suzuki; Y. Tamura; M. Nishi; T. Morii; H. Ide; K. Makino

  Nucleic acids symposium series, 1992, Peer-reviewed

  
• Separation and characterization of diastereoisomeric oligonucleotide.

  A. Murakami; Y. Tamura; M. Nishi; T. Morii; H. Ide; K. Makino

  Nucleic acids symposium series, 1992, Peer-reviewed

  
• Effects of base damages on DNA replication--mechanism of preferential purine nucleotide insertion opposite abasic site in template DNA.

  H. Ide; H. Murayama; A. Murakami; T. Morii; K. Makino

  Nucleic acids symposium series, 1992, Peer-reviewed

  
• Sequence-specific DNA recognition by basic peptides.

  T. Morii; M. Shimomura; I. Saito; H. Ide; A. Murakami; K. Makino

  Nucleic acids symposium series, 1992, Peer-reviewed

  
• Syntheses and properties of fluorescent labeled oligonucleotides containing deoxyethenoadenosine at 5\\' end.

  A. Murakami; K. Otoi; N. Fujimura; T. Morii; H. Ide; K. Makino

  Nucleic acids symposium series, 1992, Peer-reviewed

  
• STRUCTURAL POLYMORPHISM IN THE MAJOR GROOVE OF A 5S RNA GENE COMPLEMENTS THE ZINC FINGER DOMAINS OF TRANSCRIPTION FACTOR-IIIA

  PW HUBER; T MORII; HY MEI; JK BARTON

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Dec. 1991, Peer-reviewed

  
• DNA recognition by synthetic peptides as a model for the dimeric proteins.

  T. Morii; M. Shimomura; S. Morimoto; I. Saito

  Nucleic acids symposium series, 1991, Peer-reviewed

  
• 22 Molecular Mechanisms of the Sequence-Specific Recognition and Cleavage Reaction of DNA by Bleomycin

  Saito Isao; Morii Takashi; Sugiyama Hiroshi; Matsuura Teruo

  Symposium on the Chemistry of Natural Products, symposium papers, 1987

  
• Structure and chemistry of alkali-labile product formed during Fe(II)-bleomycin-mediated DNA strand scission.

  H. Sugiyama; T. Morii; I. Saito; T. Matsuura; S.M. Hecht

  Nucleic acids symposium series, 1986, Peer-reviewed

  
• “亜硝酸および一酸化窒素による新規DNA傷害の反応性”

  鈴木利典; 中村隆徳; 山田真希; 金折賢二; 田嶋邦彦; 森井 孝; 牧野圭祐

  99.5生化学会近畿支部, Peer-reviewed

  

Presentations

• Molecular recognition and functionalization of nucleic acid and protein assemblies

  T. Morii

  第50回国際核酸化学シンポジウム (2023 ISNAC), 02 Nov. 2023, Invited

  
• 生物エネルギーシステムの実現に向けた課題

  森井孝

  第2回シンビオ社会研究会講演会, 12 Oct. 2023, Invited

  
• Spatially organized assembly of enzymes on DNA nanostructures

  T. Morii

  Pacifichem2021, 19 Dec. 2021, Invited

  
• Chemistry of Spatially organized Meeting

  Takashi Morii

  Asian Chemical Biology Initiative 2021 Online Meeting, Invited

  
• 空間配置を制御した酵素集合体の化学

  森井孝

  新学術領域「分子夾雑の生命化学」 第２回関西地区シンポジウム, 17 Dec. 2019, Invited

  
• Spatially organized assembly of enzymes on DNA nanostructures

  T. Morii

  Trends in Nucleic Acid (TINA) 2019, Invited

  
• Chemical view of natural assemblies by proteins and nucleic acids

  T. Morii

  The international symposium of biofunctional chemistry, 06 Apr. 2019, Invited

  
• Assembling Enzymes on a DNA scaffold by modular protein-tag

  T. Morii

  A3RONA, Invited

  
• Chemistry of spatially organized biological molecules

  T. Morii

  ACBI, Invited

  
• 高効率な多段階酵素反応を実現するDNAナノリアクターの創製酵素を “1分子ずつ” 狙った場所に配置する

  中田栄司; 森井孝

  生体機能関連化学部会若手の会 第29回サマースクール, 10 Jul. 2017, Invited

  
• A Bioorganic Chemistry Approach to Understanding Molecular Recognition in Protein-Nucleic Acid Complexes

  MORII Takashi

  The 97th CSJ Annual Meeting, 16 Mar. 2017, The Chemical Society of Japan, Invited

  
• 細胞内セカンドメッセンジャーに対する分子センサーの構築

  森井 孝

  第16回日本蛋白質科学会年会, 07 Jun. 2016, 日本蛋白質科学会, Invited

  
• Spatially organized assembly of enzymes on the DNA scaffold

  MORII Takashi

  A3RONA(The Asian 3 Roundtable on Nucleic Acids), 19 Sep. 2015

  
• Spatially organized assembly of enzymes and receptors on the molecular switchboard

  MORII Takashi

  Cutting-edge Technologies for New Drug Diacovery and Development, 05 Feb. 2015, BK21 PLUS R-FIND, Open Translational Research Center for Innovative Drug, Invited

  
• Spatially organized assembly of enzymes on the molecular switchboard

  MORII Takashi

  Special Faculty Seminar, 03 Feb. 2015, Graduate School of Pharamaceutical Sciences, Ewha Univ., Invited

  
• 折り紙でつくる化学コンビナート

  森井 孝

  第９回京都大学附置研究所・センターシンポジウム, 15 Mar. 2014

  
• Construction of biomolecular assemblies: From ribonucleopeptides to molecular switchboards

  MORII Takashi

  Department Seminar, 26 Feb. 2014, Invited

  
• Construction of Protein Assemblies on Molecular Switchboard

  MORII Takashi

  Asian Chemical Biology Initiative 2014 Manila Meeting, 25 Jan. 2014, Asian Chemical Biology Initiative, Invited

  
• 生物がエネルギーを利用するしくみを化学で考える

  森井 孝

  京都大学エネルギー理工学研究所附属エネルギー複合機構研究センター 第７回談話会, 21 Nov. 2013, 京都大学エネルギー理工学研究所附属エネルギー複合機構研究センター

  
• アダプターを用いたDNAオリガミへのタンパク質１分子配置

  森井 孝

  戦略目標「プロセスインテグレーションによる次世代ナノシステムの創製」 ３研究領域合同公開シンポジウム, 17 Oct. 2013

  
• ssembly of enzymes on molecular switchboards

  MORII Takashi

  文部科学省特別経費プロジェクト「革新的高効率太陽光利用技術の開発」シンポジウム, 02 Oct. 2013, Kyoto Univ.

  
• Exploring novel principles for highly efficient utilization of solar energy

  MORII Takashi

  第４回エネルギー理工学研究所国際シンポジウム, 01 Oct. 2013, Kyoto Univ.

  
• DNAナノ構造体による機能性タンパク質組織体の構築

  森井 孝

  高分子討論会, 12 Sep. 2013, 高分子学会

  
• Construction of Protein Assemblies on Molecular Switchboard

  MORII Takashi

  A3RONA2013, 31 Aug. 2013, FIBER Konan Univ., Invited

  
• １分子のタンパク質を操作する：バイオエネルギー研究の新しい展開

  森井 孝

  第９回京都大学宇治キャンパス産学交流会, 28 Jun. 2013, 京都府中小企業技術センターけいはんな分室

  
• 単一細胞内での複数のセカンドメッセンジャー代謝動態リアルタイム計測

  森井 孝

  新学術領域研究「過渡的複合体」班会議, 09 May 2013, 日本学術振興会