Basic Information

Faculty

• 農学部

Professional Memberships

• The Japanese Society of Veterinary Science
• 関西畜産学会
• Society for Reproduction and Development
• Japanese Society of Animal Science
• The Japanese Society of Veterinary Science
• Society for Reproduction and Development
• Japanese Society of Animal Science

Academic Degree

• 修士（農学）(京都大学)
• 博士（農学）(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院農学研究科修士課程畜産学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 農学部畜産学科, 卒業

Research History

• From 2007, To Present

  - 京都大学大学院農学研究科 助教
• From 2007, To Present

  - Assistant professor, Graduate School of Agriculture, Kyoto University
• From 1997, To 2007

  Kyoto University, Graduate School of Agriculture
• From 1997, To 2007

  Instructor, Graduate School of Agriculture, Kyoto University
• From 1992, To 1997

  Kyoto University, Faculty of Agriculture
• From 1992, To 1997

  Instructor, Faculty of Agriculture, Kyoto University

Language of Instruction

• English

ID,URL

• J-Global ID

  200901094880599243

researchmap URL

• https://researchmap.jp/read0013131

Research

Research Topics, Overview of the research

• Research Topics

  Functional morphology of mammals, especially of development and functions of the female reproductive system.

• Overview of the research

  The main theme of my research is the analysis of factors participating in the development and functional control of the ovary which is the production organ of female germ cells (oocytes and ova) of the mammal and the development of techniques for effective utilization. In conjunction with this, endogenous and exogenous factors influencing the maternal and neonatal physiology are included in my research subject. I also have been participating in several other studies in charge of morphological analyses.

Research Interests

• Ovaris
• Female germ cells
• mammals
• Anatomy and physiology
• Animal production science-related
• 機能形態学
• 生体機構学
• functional anatomy
• Animal physiology

Research Areas

• Life sciences, Veterinary medicine
• Life sciences, Animal production science

Papers

• High-fat/high-sucrose diet-induced renal changes in obese diabetic mice: a comparison with <i>db/db </i>and KK-Ay mice

  Chika OKI; Kinuko UNO; Tomohiko SASASE; Takahiro TSUTSUI; Keita SEKIGUCHI; Ayane YAMAGUCHI; Kouhei MANDAI; Masami SHINOHARA; Miki SUGIMOTO; Tatsuya MAEKAWA; Katsuhiro MIYAJIMA; Takeshi OHTA

  Journal of Veterinary Medical Science, 2024

  
• Salt loading with unilateral nephrectomy accelerates decline in glomerular filtration rate in the hypertensive, obese, type 2 diabetic SDT fatty rat model of diabetic kidney disease.

  Yuichi Shinozaki; Yuko Katayama; Fuminari Yamaguchi; Tomohisa Suzuki; Kana Watanabe; Kinuko Uno; Takahiro Tsutsui; Miki Sugimoto; Masami Shinohara; Katsuhiro Miyajima; Takeshi Ohta

  Clinical and experimental pharmacology & physiology, Apr. 2022, Peer-reviewed

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• Pathophysiological features in the brains of female Spontaneously Diabetic Torii (SDT) fatty rats.

  Tatsuya Maekawa; Miki Sugimoto; Shinichi Kume; Takeshi Ohta

  The Journal of veterinary medical science, 03 Mar. 2022, Peer-reviewed

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• Figla promotes secondary follicle growth in mature mice.

  Asuka Okunomiya; Akihito Horie; Hirohiko Tani; Yukiyasu Sato; Shiro Takamatsu; J B Brown; Miki Sugimoto; Junzo Hamanishi; Eiji Kondoh; Noriomi Matsumura; Masaki Mandai

  Scientific reports, 10 May 2021, Peer-reviewed

  
• Glomerular Hyperfiltration With Hyperglycemia in the Spontaneously Diabetic Torii (SDT) Fatty Rat, an Obese Type 2 Diabetic Model

  Ryuhei Sano; Yukihito Ishii; Masao Yamanaka; Yuzo Yasui; Yusuke Kemmochi; Fuko Kuroki; Miki Sugimoto; Sumiaki Fukuda; Tomohiko Sasase; Katsuhiro Miyajima; Dai Nakae; Takeshi Ohta

  Physiological Research, Feb. 2021, Peer-reviewed

  
• Embryonic MTHFR contributes to blastocyst development.

  Hiroki Ishitani; Shuntaro Ikeda; Kai Egashira; Miki Sugimoto; Shinichi Kume; Naojiro Minami; Takeshi Ohta

  Journal of assisted reproduction and genetics, Aug. 2020, Peer-reviewed

  
• The RPMI-1640 vitamin mixture promotes bovine blastocyst development in vitro and downregulates gene expression of TXNIP with epigenetic modification of associated histones

  S. Ikeda; M. Sugimoto; S. Kume

  Journal of Developmental Origins of Health and Disease, 01 Feb. 2018, Peer-reviewed

  
• Lipofection of siRNA into bovine 8-16-cell stage embryos using zona removal and the well-of-the-well culture system

  Shuntaro Ikeda; Miki Sugimoto; Shinichi Kume

  Journal of Reproduction and Development, 2018, Peer-reviewed

  
• 黒毛和種繁殖牛の分娩直後の血漿中免疫グロブリン濃度の変動要因と分娩後の血漿中免疫グロブリン濃度に及ぼす乾燥ニンジン給与の影響

  石田 真穂; 西島 嘉隆; 谷口 紗耶; 北村 勇人; 池田 俊太郎; 葭谷 健一; 濱野 貴史; 谷 浩; 藤田 雅彦; 村上 賢司; 小草 啓輔; 佐藤 健史; 杉本 実紀; 久米 新一

  日本畜産学会報, Nov. 2017, Peer-reviewed

  
• Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions

  Shuntaro Ikeda; Ryouka Kawahara-Miki; Hisataka Iwata; Miki Sugimoto; Shinichi Kume

  SCIENTIFIC REPORTS, Jun. 2017, Peer-reviewed

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• Effects of beta-carotene-enriched dry carrots on beta-carotene status and colostral immunoglobulin in beta-carotene-deficient Japanese Black cows

  Yoshitaka Nishijima; Saya Taniguchi; Shuntaro Ikeda; Kenichi Yoshitani; Takashi Hamano; Hiroshi Tani; Masahiko Fujita; Kenji Murakami; Keisuke Kogusa; Kenji Sato; Miki Sugimoto; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, Apr. 2017, Peer-reviewed

  
• 泌乳マウスの小腸と乳腺における免疫グロブリンＡ産生に及ぼす乾燥ニンジンの影響

  阪上真優; 池田俊太郎; 杉本実紀; 小草啓輔; 佐藤健史; 久米新一

  関西畜産学会報, Feb. 2017, Peer-reviewed

  
• 離乳仔マウスと泌乳マウスのIgA産生に及ぼすペプチド亜鉛の影響

  橋本 知明; 松山 奈央; 杉本 実紀; 池田 俊太郎; 久米 新一

  微量栄養素研究, Dec. 2016, Peer-reviewed

  
• Relationships between immunoglobulin M and immunoglobulin G or A in colostrum of Japanese black multiparous cows

  Saya Taniguchi; Mengdong Wang; Shuntaro Ikeda; Hidetugu Yoshioka; Hiroshi Nagase; Shoko Kitamura; Erina Itoyama; Hiroaki Murakami; Miki Sugimoto; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, Apr. 2016, Peer-reviewed

  
• 離乳後マウスの小腸におけるIgA産生に及ぼすビタミンCの影響

  泉谷 紗也佳; 杉本 実紀; 池田 俊太郎; 久米 新一

  微量栄養素研究, Dec. 2015, Peer-reviewed

  
• Methionine-dependent histone methylation at developmentally important gene loci in mouse preimplantation embryos

  Mari Kudo; Shuntaro Ikeda; Miki Sugimoto; Shinichi Kume

  JOURNAL OF NUTRITIONAL BIOCHEMISTRY, Dec. 2015, Peer-reviewed

  
• 黒毛和種繁殖牛の初乳中免疫グロブリン含量に及ぼす乾燥ニンジン給与の影響

  谷口 紗耶; 王 蒙東; 池田 俊太郎; 吉岡 秀貢; 長瀬 祐士; 北村 祥子; 糸山 恵理奈; 村上 弘明; 小草 啓輔; 佐藤 健史; 杉本 実紀; 久米 新一

  日本畜産学会報, Nov. 2015

  
• 泌乳マウスの乳腺における免疫グロブリンA産生に及ぼすガラクトオリゴ糖の影響

  酒井 豪太; 前田 佳祐; 杉本 実紀; 池田 俊太郎; 木村 一雅; 久米 新一

  日本畜産学会報, Aug. 2015

  
• Relationships between immunoglobulin and fat-soluble vitamins in colostrum of Japanese Black multiparous cows

  Mengdong Wang; Shuntaro Ikeda; Hidetugu Yoshioka; Hiroshi Nagase; Shoko Kitamura; Erina Itoyama; Hiroaki Murakami; Miki Sugimoto; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, Jul. 2015, Peer-reviewed

  
• Effects of potassium chloride level on water intake and renal function in lactating mice

  宿院 享; 杉本 実紀; 池田 俊太郎; 久米 新一

  日本畜産学会報, Nov. 2014, Peer-reviewed

  
• The Effects of Calcitonin on the Development of and Ca2+ Levels in Heat-shocked Bovine Preimplantation Embryos In Vitro

  Shumpei Kamano; Shuntaro Ikeda; Miki Sugimoto; Shinichi Kume

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Aug. 2014, Peer-reviewed

  
• Effects of astaxanthin-enriched yeast on mucosal IgA induction in the jejunum and ileum of weanling mice

  Tatsuhiko Nagayama; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, Apr. 2014, Peer-reviewed

  
• Effects of supplemental β-cryptoxanthin on IgA-secreting cells in the intestine and mammary glands of lactating mice.

  Wang M; Sugimoto M; Ikeda S; Mukai K; Kume S

  Trace Nutrient Research, 2014, Peer-reviewed

  
• Effects of supplemental beta-carotene on mucosal IgA induction in the jejunum and ileum of mice after weaning

  Keita Nishida; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  BRITISH JOURNAL OF NUTRITION, Jan. 2014, Peer-reviewed

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• Astaxanthin ameliorates heat stress-induced impairment of blastocyst development In Vitro: -astaxanthin colocalization with and action on mitochondria-

  T. Kuroki; S. Ikeda; T. Okada; T. Maoka; A. Kitamura; M. Sugimoto; S. Kume

  JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, Jun. 2013, Peer-reviewed

  
• Effects of high potassium chloride supplementation on water intake and bodyweight gains in pregnant and lactating mice

  Iori Murai; Susumu Shukuin; Miki Sugimoto; Shuntaro Ikeda; Shin-ichi Kume

  Animal Science Journal, Jun. 2013, Peer-reviewed

  
• Effects of coumestrol administration to maternal mice during pregnancy and lactation on immunoblogulin A-secreting cells in mammary glands

  Mengdong Wang; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  Animal Science Journal, Apr. 2013, Peer-reviewed

  
• Effects of Folic Acid on the Development and Oxidative Stress of Mouse Embryos Exposed to Heat Stress

  H. Koyama; S. Ikeda; M. Sugimoto; S. Kume

  REPRODUCTION IN DOMESTIC ANIMALS, Dec. 2012, Peer-reviewed

  
• Investigation of hydration processes of the equine hoof via nuclear magnetic resonance microscopy

  Miki Sugimoto; Atsutoshi Kuwano; Shuntaro Ikeda; Shin-ichi Kume; Eiru Yoshihara; Shinya Wada

  AMERICAN JOURNAL OF VETERINARY RESEARCH, Nov. 2012, Peer-reviewed

  
• Whole-body distribution of C-14-labeled silica nanoparticles and submicron particles after intravenous injection into Mice

  Nobumitsu Sakai; Masato Takakura; Harutoshi Imamura; Miki Sugimoto; Yasuto Matsui; Hirokazu Miyoshi; Aki Nakayama; Minoru Yoneda

  JOURNAL OF NANOPARTICLE RESEARCH, May 2012, Peer-reviewed

  
• Effect of RNA Interference of BID and BAX mRNAs on Apoptosis in Granulosa Cell-derived KGN Cells

  Takafumi Sai; Fuko Matsuda; Yasufumi Goto; Akihisa Maeda; Miki Sugimoto; Hong-Mei Gao; Abul Khair Mohammad Ahan Kabir; Jun-You Li; Noboru Manabe

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Feb. 2012, Peer-reviewed

  
• Importance of Methionine Metabolism in Morula-to-blastocyst Transition in Bovine Preimplantation Embryos

  Shuntaro Ikeda; Miki Sugimoto; Shinichi Kume

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Feb. 2012, Peer-reviewed

  
• Roles of One-carbon Metabolism in Preimplantation Period-Effects on Short-term Development and Long-term Programming-

  Shuntaro Ikeda; Hiroyuki Koyama; Miki Sugimoto; Shinichi Kume

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Feb. 2012, Peer-reviewed

  
• Effects of coumestrol administration to maternal mice during pregnancy and lactation on renal Ca metabolism in neonatal mice

  Michihisa Ueda; Yoshihiro Horiguchi; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, 2012, Peer-reviewed

  
• Effects of bisphenol A administration to pregnant mice on serum Ca and intestinal Ca absorption

  Hinako Otsuka; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  ANIMAL SCIENCE JOURNAL, 2012, Peer-reviewed

  
• ICRマウスにおける44nm14C標識シリカナノ粒子を用いた体内動態評価モデルの構築

  今村治世; 髙倉誠人; 坂井伸光; 中山亜紀; 佐々木克典; 真見一樹; 三好弘一; 杉本実紀; 米田稔

  土木学会論文集G(環境) 67(7): Ⅲ_223-Ⅲ_232., Dec. 2011, Peer-reviewed

  
• Bid and Bax Are Involved in Granulosa Cell Apoptosis During Follicular Atresia in Porcine Ovaries

  Takafumi Sai; Yasufumi Goto; Ryousuke Yoshioka; Akihisa Maeda; Fuko Matsuda; Miki Sugimoto; Kannika Wongpanit; Hua-Zi Jin; Jun-You Li; Noboru Manabe

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Jun. 2011, Peer-reviewed

  
• Effects of Coumestrol Administration to Pregnant and Lactating Mice on Intestinal Alkaline Phosphatase Activity

  Yuka Kirihata; Yoshihiro Horiguchi; Michihisa Ueda; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  PHYTOTHERAPY RESEARCH, May 2011, Peer-reviewed

  
• Effects of supplemental beta-carotene with whey on IgA transfer from maternal milk and mucosal IgA induction in neonatal mice and calves

  Y. Nishiyama; K. Yasumatsuya; K. Kasai; M. Sakase; O. Nishino; M. Akaike; T. Nagase; M. Sugimoto; S. Ikeda; S. Kume

  LIVESTOCK SCIENCE, May 2011, Peer-reviewed

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• Supplemental beta-carotene increases IgA-secreting cells in mammary gland and IgA transfer from milk to neonatal mice

  Yoshitaka Nishiyama; Miki Sugimoto; Shuntaro Ikeda; Shinichi Kume

  BRITISH JOURNAL OF NUTRITION, Jan. 2011, Peer-reviewed

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• Effects of Astaxanthin-containing Oil on Development and Stress-related Gene Expression of Bovine Embryos Exposed to Heat Stress

  T. Namekawa; S. Ikeda; M. Sugimoto; S. Kume

  REPRODUCTION IN DOMESTIC ANIMALS, Dec. 2010, Peer-reviewed

  
• Changes in the Expression of Decoy Receptor 3 in Granulosa Cells During Follicular Atresia in Porcine Ovaries

  Miki Sugimoto; Noriko Kagawa; Maki Morita; Shinichi Kume; Kannika Wongpanit; Huazi Jin; Noboru Manabe

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Aug. 2010, Peer-reviewed

  
• Dynamic Expression of Vimentin in Bovine Blastocysts in Extended In Vitro Culture

  S. Ikeda; M. Sugimoto; S. Kume

  REPRODUCTION IN DOMESTIC ANIMALS, Apr. 2010, Peer-reviewed

  
• Expression of Methylation Pathway Enzymes in Bovine Oocytes and Preimplantation Embryos

  Shuntaro Ikeda; Takahiro Namekawa; Miki Sugimoto; Shin-Ichi Kume

  JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL GENETICS AND PHYSIOLOGY, Mar. 2010, Peer-reviewed

  
• 離乳後のマウスの窒素利用効率および糞中IgAに及ぼすホエータンパク質あるいは脱脂乳タンパク質給与の影響

  高木菜穂子; 長谷川清香; 池田俊太郎; 杉本実紀; 久米新一

  関西畜産学会報 166: 1-9，2010, 2010, Peer-reviewed

  
• Effects of high potassium chloride supplementation on water intake, urine volume and nitrogen balance in mice

  Iori Murai; Miki Sugimoto; Shuntaro Ikeda; Shin-ichi Kume

  ANIMAL SCIENCE JOURNAL, 2010, Peer-reviewed

  
• Atg26-Mediated Pexophagy Is Required for Host Invasion by the Plant Pathogenic Fungus Colletotrichum orbiculare

  Makoto Asakura; Sachiko Ninomiya; Miki Sugimoto; Masahide Oku; Shun-ichi Yamashita; Tetsuro Okuno; Yasuyoshi Sakai; Yoshitaka Takano

  PLANT CELL, Apr. 2009, Peer-reviewed

  
• Effects of high potassium chloride supplementation on growth rate and renal function in mice

  Iori Murai; Satoshi Imanishi; Miki Sugimoto; Shin-Ichi Kume

  ANIMAL SCIENCE JOURNAL, Apr. 2008, Peer-reviewed

  
• Coumestrol decreases intestinal alkaline phosphatase activity in post-delivery mice but does not affect vitamin D receptor and calcium channels in post-delivery and neonatal mice

  Yuka Kirihata; Tetsu Kawarabayashi; Satoshi Imanishi; Miki Sugimoto; Shin-Ichi Kume

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Feb. 2008, Peer-reviewed

  
• Changes in expression and localization of GPRC5B and RAR alpha in the placenta and yolk sac during middle to late gestation in mice

  Satoshi Imanishi; Miki Sugimoto; Maki Morita; Shinichi Kume; Noboru Manabe

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Oct. 2007, Peer-reviewed

  
• Identification, isolation, and in vitro culture of porcine gonocytes

  Sandeep Goel; Miki Sugimoto; Naojiro Minami; Masayasu Yamada; Shinichi Kume; Hiroshi Imai

  Biology of Reproduction, Jul. 2007, Peer-reviewed

  
• A physiologically based pharmacokinetic model for endosulfan in the male Sprague-Dawley rats

  Melissa R. L. Chan; Shinsuke Morisawa; Aki Nakayama; Yuko Kawamoto; Miki Sugimoto; Minoru Yoneda

  ENVIRONMENTAL TOXICOLOGY, Oct. 2006, Peer-reviewed

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• Toxicokinetics of C-14-endosulfan in male Sprague-Dawley rats following oral administration of single or repeated doses

  MPL Chan; S Morisawa; A Nakayama; Y Kawamoto; M Sugimoto; M Yonedal

  ENVIRONMENTAL TOXICOLOGY, Oct. 2005, Peer-reviewed

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• Application of magnetic resonance microscopy to examination of small experimental animals

  杉本実紀

  京都大学低温物質科学研究センター誌, Jun. 2005, Peer-reviewed

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• Effects of in utero exposure to bisphenol a on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos

  H Nishizawa; M Morita; M Sugimoto; S Imanishi; N Manabe

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Jun. 2005, Peer-reviewed

  
• Disposition of bisphenol A in pregnant mice and fetuses after a single and repeated oral administration

  Yuko Kawamoto; Wakoto Matsuyama; Masahiro Morikawa; Maki Morita; Miki Sugimoto; Noboru Manabe; Shinsuke Morisawa

  Toxicological and Environmental Chemistry, Apr. 2005, Peer-reviewed

  
• Microtubule organization during rabbit fertilization by intracytoplasmic sperm injection with and without sperm centrosome

  Junko Morita; Yukihiro Terada; Yoshihiko Hosoi; Nahoko Fujinami; Miki Sugimoto; Sou-Ichi Nakamura; Takashi Murakami; Nobuo Yaegashi; Kunihiro Okamura

  Reproductive Medicine and Biology, 2005, Peer-reviewed

  
• Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia

  Noboru Manabe; Naoke Inoue; Miki Sugimoto; Hajime Miyamoto; Takashi Miyano; Kazuhiro Sakamaki

  The Ovary: Second Edition, 18 Dec. 2003, Peer-reviewed

  
• Effects of In utero exposure to bisphenol A on expression of RAR alpha and RXR alpha mRNAs in murine embryos

  H Nishizawa; N Manabe; M Morita; M Sugimoto; S Imanishi; H Miyamoto

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Dec. 2003, Peer-reviewed

  
• Effects of oral exposure of bisphenol a on mRNA expression of nuclear receptors in murine placentae assessed by DNA microarray

  S Imanishi; N Manabe; H Nishizawa; M Morita; M Sugimoto; M Iwahori; H Miyamoto

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Aug. 2003, Peer-reviewed

  
• 卵巣組織の凍結保存

  杉本実紀; 真鍋昇; 宮本元

  医学のあゆみ, 29 Mar. 2003

  
• mRNA of GPRC5B/Raig2, a novel orphan receptor, expresses in murine placentae

  S Imanishi; N Manabe; T Tanaka; R Okamoto; M Morita; M Sugimoto; H Miyamoto

  JOURNAL OF REPRODUCTION AND DEVELOPMENT, Dec. 2002, Peer-reviewed

  
• Availability of NMR microscopic observation of mouse embryo disorder: Examination in malformations induced by maternal administration of retinoic acid

  M Sugimoto; N Manabe; M Morita; T Tanaka; R Okamoto; S Imanishi; H Miyamoto

  JOURNAL OF VETERINARY MEDICAL SCIENCE, May 2002, Peer-reviewed

  
• 化学物質の後世代への影響の評価法開発 (特集 化学物質の安全)

  眞鍋昇; 杉本実紀; 宮本元

  ケミカルエンジニヤリング, Feb. 2002

  
• 【生殖医療におけるニューテクノロジー】 卵巣凍結法

  杉本実紀; 眞鍋昇; 宮本元

  HORMONE FRONTIER IN GYNECOLOGY 9(2): 135-140., 2002

  
• Physiological Roles of Apoptosis in Granulosa Cells of Atretic Follicles in Porcine Ovaries

  MANABE Noboru; SUGIMOTO Miki; NAKAYAMA Mizuho; INOUE Naoko; KISO Minako; YAMAGUCHI Misuzu; TANAKA Takaoko; YAMADA-UCHIO Kozue; MIYAMOTO Hajime

  日本胚移植学雑誌 = Japanese journal of embryo transfer, 16 Jan. 2001

  
• 【生殖医療 21世紀の展望】 卵巣凍結の現状と展望

  杉本実紀; 眞鍋昇; 宮本元

  産科と婦人科 68(2): 207-212., 2001

  
• A Novel Cell Death Receptor and a Decoy Receptor on Follicular Granulosa Cells of Porcine Ovaries

  MANABE Noboru; NAKAYAMA Mizuho; YAMAGUCHI Misuzu; KISO Minako; TANAKA Takako; INOUE Naoko; YAMADA-UCHIO Kozue; SUGIMOTO Miki; MIYAMOTO Hajime

  日本胚移植学雑誌 23(2): 52-60., 2001

  
• A novel in vivo P-31-nuclear magnetic resonance technique for assessment of liver failure induced by chlorinated-hydrocarbon in mice

  N Manabe; Y Azuma; M Sugimoto; T Tanaka; N Kiso; M Yamaguchi; K Uchio-Yamada; H Miyamoto

  BIOMEDICAL RESEARCH-TOKYO, Dec. 2000, Peer-reviewed

  
• Development of infantile rat ovaries autotransplanted after cryopreservation by vitrification

  M Sugimoto; S Maeda; N Manabe; H Miyamoto

  THERIOGENOLOGY, Mar. 2000, Peer-reviewed

  
• Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism and blood flow in dietary hypoferric anaemic mice

  N Manabe; Y Azuma; M Sugimoto; K Uchio; M Miyamoto; N Taketomo; H Tsuchita; H Miyamoto

  BRITISH JOURNAL OF NUTRITION, Feb. 2000, Peer-reviewed

  
• 【受精卵と精子などの凍結保存】 哺乳動物卵巣の凍結保存

  杉本実紀; 眞鍋昇; 宮本元

  組織培養工学 26(2): 48-51., 2000

  
• 発生学における機能形態学的解析の将来

  杉本実紀; 真鍋昇; 宮本元

  The Journal of Reproduction and Development 46(Suppl.): j71-j77., 2000

  
• 【内分泌撹乱化学物質】 内分泌攪乱化学物質試験法 スクリーニング試験法,測定法,毒性試験 生体核磁気共鳴装置による胎児への影響の評価法

  眞鍋昇; 杉本実紀; 森田眞紀; 田中宇子; 山口美鈴; 宮本元

  日本臨床(0047-1852) 58(12): 2482-2485., 2000

  
• 技術報文 生体核磁気共鳴イメージング法による環境汚染物質の胎児への影響の非侵襲的評価法

  眞鍋 昇; 杉本 実紀; 森田 眞紀

  環境と測定技術, 2000

  
• Comparison of nuclear magnetic resonance microimages and histology of rat ovaries

  Miki Sugimoto; Noboru Manabe; Maki Morita; Hajime Miyamoto

  Journal of Reproduction and Development, 2000, Peer-reviewed

  
• Interactions of Apoptosis and Extracellular Matrices in Granulosa Cells of Atretic Follicles in Porcine Ovaries

  Yuzuru Imai; Noboru Manabe; Kozue Uchio; Hiroko Matsushita; Yoshihiro Kimura; Mizuho Nakayama; Susumu Nishihara; Satoko Wada; Miki Sugimoto; Hajime Miyamoto

  Journal of Mammalian Ova Research, 1999, Peer-reviewed

  
• 【生殖細胞の選択】 哺乳動物における卵の選択

  眞鍋昇; 内尾こずえ; 杉本実紀; 宮本元

  組織培養工学 25(1): 4-8., 1999

  
• 環境ホルモン(内分泌撹乱物質)研究の展開 哺乳類発生異常の構造生物学的評価のアプローチ

  眞鍋昇; 杉本実紀

  医学のあゆみ 190(7〜8): 744., 1999

  
• Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia - Role of granulosa cell apoptosis in porcine ovarian follicle atresia

  N Manabe; Y Kimura; K Uchio; C Tajima; H Matsushita; M Nakayama; M Sugimoto; H Miyamoto

  ANIMAL CELL TECHNOLOGY: CHALLENGES FOR THE 21ST CENTURY, 1999, Peer-reviewed

  
• Ultrastructural changes in granulosa cells in porcine antral follicles undergoing atresia indicate apoptotic cell death

  Miki Sugimoto; Noboru Manabe; Yoshihiro Kimura; Akira Myoumoto; Yuzuru Imai; Hiroko Ohno; Hajime Miyamoto

  Journal of Reproduction and Development, 1998, Peer-reviewed

  
• Monoclonal antibodies against pig ovarian follicular granulosa cells induce apoptotic cell death in cultured granulosa cells

  A Myoumoto; N Manabe; Y Imai; Y Kimura; M Sugimoto; Y Okamura; M Fukumoto; K Sakamaki; Y Niwano; H Miyamoto

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Aug. 1997, Peer-reviewed

  
• Morphological Effects of Protein Kinase C Activators in Mouse Late Morulae

  Takahisa Noto; Shinnji Maeda; Yayoi Toyooka; Tomohiko Okuda; Miki Sugimoto; Hajime Miyamoto; Noboru Manabe

  Journal of Mammalian Ova Research, 1997, Peer-reviewed

  
• Ultrastructural Features of Secretion by Murine Oviductal Epithelium

  Maki Morita; Miki Sugimoto; Hajime Miyamoto; Noboru Manabe

  Journal of Mammalian Ova Research, 1997, Peer-reviewed

  
• Alterations in cell proliferation and morphology of ampullar epithelium of the mouse oviduct during the estrous cycle

  Maki Morita; Hajime Miyamoto; Miki Sugimoto; Nami Sugimoto; Noboru Manabe

  Journal of Reproduction and Development, 1997, Peer-reviewed

  
• Apoptosis occurs in granulosa cells but not cumulus cells in the atretic graafian follicles in multiparous pig ovaries

  N Manabe; Y Imai; A Myoumoto; Y Kimura; M Sugimoto; Y Okamura; M Fukumoto; K Sakamaki; H Miyamoto

  ACTA HISTOCHEMICA ET CYTOCHEMICA, 1997, Peer-reviewed

  
• A monoclonal antibody against pig ovarian follicular granulosa cells recognizes a novel cell death receptor and induces granulosa cell apoptosis

  N Manabe; A Myoumoto; Y Kimura; Y Imai; M Sugimoto; H Miyamoto

  ADVANCES IN COMPARATIVE ENDOCRINOLOGY, TOMES 1 AND 2, 1997, Peer-reviewed

  
• Follicle survival in neonatal rat ovaries cryoreserved by vitrification

  M Sugimoto; H Miyamoto; T Kabasawa; N Manabe

  CRYO-LETTERS, Mar. 1996, Peer-reviewed

  
• Apoptosis occurs in granulosa cells but not cumulus cells in the atretic antral follicles in pig ovaries

  N. Manabe; Y. Imai; H. Ohno; Y. Takahagi; M. Sugimoto; H. Miyamoto

  Experientia, 1996, Peer-reviewed

  
• Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse

  N Manabe; M Sugimoto; Y Azuma; N Taketomo; A Yamashita; H Tsuboi; A Tsunoo; N Kinjo; H NianLai; H Miyamoto

  JAPANESE JOURNAL OF PHARMACOLOGY, Jan. 1996, Peer-reviewed

  
• Ca2+/Mg2+-dependent endonuclease but not Ca 2+-dependent, Mg2+-dependent or cation-independent endonuclease is involved in granulosa cell apoptosis of pig atretic follicles

  Noboru Manabe; Yuzuru Imai; Yoshihiro Kimura; Akira Myoumoto; Miki Sugimoto; Hajime Miyamoto; Yoshinori Okamura; Manabu Fukumoto

  Journal of Reproduction and Development, 1996, Peer-reviewed

  
• Signal transmission of granulosa cell apoptosis in the atretic antral follicles in the pig ovaries

  Manabe N; Myoumoto A; Kimura Y; Imai Y; Sakamaki K; Okamura Y; Fukumoto M; Sugimoto M; Miyamoto H

  J Reprod Develop, 1996, Peer-reviewed

  
• Histochemical Studies in the Perfused Goat Ovary

  MIYAMOTO Hajime; FUKURA Hakobu; ARAI Takeshi; NOMOTO Hideo; MANABE Noboru; SUGIMOTO Miki; ABE Harutoshi; MORITA Maki

  日本胚移植学雑誌 = Japanese journal of embryo transfer, 25 Jun. 1995

  
• THE FUNCTIONAL MORPHOLOGY OF GOAT OVIDUCTAL SECRETION

  MORITA Maki; MIYAMOTO Hajime; SUGIMOTO Miki

  日本胚移植学雑誌 = Japanese journal of embryo transfer, 25 Jun. 1995

  
• The Secretory Cells of the Goat Oviductal Epithelium: An Ultrastructural Study

  Maki Morita; Hajime Miyamoto; Takashi Ishii; Miki Sugimoto

  Journal of Reproduction and Development, 1995, Peer-reviewed

  
• A MORPHOMETRIC STUDY OF SPERMATOGENESIS IN THE TESTES OF MICE OF A SENESCENCE-ACCELERATED STRAIN

  H MIYAMOTO; N MANABE; Y AKIYAMA; T WATANABE; M SUGIMOTO; E SATO

  EXPERIENTIA, Sep. 1994, Peer-reviewed

  
• QUANTITATIVE STUDIES ON SPERMATOGENESIS IN THE SENESCENCE-ACCELERATED MOUSE

  H MIYAMOTO; N MANABE; Y AKIYAMA; Y MITANI; M SUGIMOTO; E SATO

  SAM MODEL OF SENESCENCE, 1994, Peer-reviewed

  
• FEMALE REPRODUCTIVE CHARACTERISTICS OF THE SENESCENCE-ACCELERATED MOUSE

  H MIYAMOTO; N MANABE; T WATANABE; C ARUGA; Y MITANI; N SUGIMOTO; M SUGIMOTO; E SATO

  SAM MODEL OF SENESCENCE, 1994, Peer-reviewed

  
• 臓器の凍結保存における問題点 ＩＩ．臓器の形態学的特徴と凍結保存法

  宮本元; 杉本実紀

  家畜繁殖技術研究会誌, May 1993

  
• 臓器の凍結保存における問題点 Ｉ． 細胞の凍害機構と臓器凍結保存の現状

  宮本元; 杉本美紀

  家畜繁殖技術研究会誌, Sep. 1992

  
• -196°Cに冷却後のラット卵巣の組織学的検討

  宮本元; 杉本実紀

  家畜繁殖技術研究会誌 13(1): 11-14., 1991

  

Misc.

• FEMALE REPRODUCTIVE PROPERTIES AND PRENATAL DEVELOPMENT OF A SENESCENCE-ACCELERATED MOUSE STRAIN

  H MIYAMOTO; N MANABE; Y MITANI; N SUGIMOTO; T WATANABE; C ARUGA; E SATO

  JOURNAL OF EXPERIMENTAL ZOOLOGY, Jun. 1995

  
• A novel in vivo 31P-nuclear magnetic resonance technique for assessment of teratogenicity induced by environmental endocrine disrupters in mice

  N. Manabe; M. Sugimoto; M. Morita; T. Tanaka; M. Yamaguchi; H. Miyamoto

  Nippon rinsho. Japanese journal of clinical medicine, 2000

  
• 西洋食負荷が肥満2型糖尿病モデルSDT fattyラットの肝臓に及ぼす病理組織学的影響

  小竹 立珠; 宇野 絹子; 杉本 実紀; 笹瀬 智彦; 鳥庭 靖文; 山田 宜永; 太田 毅

  日本毒性病理学会講演要旨集, Jan. 2024

  
• Pathophysiological analysis of the kidneys in obese type 2 diabetes model db/db mice fed a high-sucrose/high-fat/high-cholesterol diet

  Ishikawa Y; Odake T; Sasase T; Handa M; Doi Y; Shinohara M; Uno K; Sugimoto M; Ohta T

  The 5th International Seminar on Smart Molecule of Natural Resources(ISSMART)-Asian Federation of Biotechnology(AFOB) 2023, Oct. 2023, Peer-reviewed

  
• Luteal cell apoptosis is regulated by soluble Fas during luteolysis in the mouse

  N Manabe; K Komatsu; M Kiso; Y Goto; M Sugimoto

  JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, Jul. 2004

  
• 肥満２型糖尿病モデルSDT fattyラットの糖尿病性腎臓病早期病変にダパグリフロジンが及ぼす影響

  篠原雅巳; 黒木楓子; 杉本実紀; 佐野龍平; 美谷島克宏; 中江大; 太田毅

  第36回 日本糖尿病・肥満動物学会, Feb. 2023

  
• ウェスタンダイエット負荷が肥満2型糖尿病モデルマウスdb/dbマウス、およびKK-Ayマウスの腸管に及ぼす影響

  武呂大和; 白坂航大; 筒井誉大; 小郷智記; 宇野絹子; 万大康平; 杉本実紀; 笹瀬智彦; 篠原雅巳; 美谷島克宏; 太田毅

  第72回 関西畜産学会, Oct. 2022

  
• 高ショ糖/高脂肪/高コレステロール食給餌が肥満2型糖尿病モデルマウスdb/dbマウス、およびKK-Ayマウスの肝臓に及ぼす影響

  白坂 航大; 武呂 大和; 筒井 誉大; 小郷 智記; 宇野 絹子; 万代 康平; 杉本 実紀; 笹瀬 智彦; 篠原 雅巳; 美谷島 克宏; 太田 毅

  日本畜産学会大会講演要旨集, Sep. 2022

  
• SDT fattyラット脳の病態生理学的特徴

  前川 竜也; 杉本 実紀; 久米 新一; 篠原 雅巳; 太田 毅

  糖尿病合併症, Sep. 2022

  
• 高ショ糖/高脂肪食給餌が肥満２型糖尿病モデルマウスdb/dbマウスおよびKK-Ayマウスの腎臓に及ぼす影響

  筒井誉大; 万代康平; 宇野絹子; 関口敬大; 白坂航大; 武呂大和; 杉本実紀; 篠原雅巳; 美谷島克宏; 笹瀬智彦; 太田毅

  第32回 日本糖尿病性腎症研究会, Dec. 2021

  
• Granulosa cell in porcine ovarian follicle is type II, mitochondrion-dependent, apoptotic cell.

  N Manabe; T Matsui; Y Goto; F Matsuda; N Inoue; A Maeda; Y Cheng; M Sugimoto

  BIOLOGY OF REPRODUCTION, 2004

  
• Follicle Developments in Neonatal Rat Ovaries Autotransplanted after Cryopreservation by Vitrification

  SUGIMOTO M.; MAEDA S.; MIYAMOTO H.

  Journal of mammalian ova research = 日本哺乳動物卵子学会誌, 01 Apr. 1997

  
• 肥満２型糖尿病モデルSDT fattyラットの糖尿病性腎臓病早期におけるダパグリフロジンの腎保護効果の検討

  篠原雅巳; 黒木楓子; 杉本実紀; 佐野龍平; 美谷島克宏; 中江大; 太田毅

  第32回 日本糖尿病性腎症研究会, Dec. 2021

  
• 新生仔期マウスへのビタミンA補給の腸管および脾臓に対する影響の検討

  水永武寿; 仲野彰紘; 太田毅; 杉本実紀

  第71回 関西畜産学会, Oct. 2021

  
• 肥満2型糖尿病モデルマウスの空腸における病態生理学的解析

  西田 芽衣; 黒木 楓子; 小郷 智記; 笹瀬 智彦; 杉本 実紀; 宇野 絹子; 美谷島 克宏; 太田 毅

  日本畜産学会大会講演要旨集, Sep. 2021

  
• Effect of high fat diet on liver in db/db and KK-Ay mice

  MANDAI Kouhei; MIYAJIMA Katsuhiro; KITAMURA Sayaka; YAMAGUCHI Ayane; UNO Kinuko; KUROKI Fuko; NISHIDA Mei; SHIRASAKA Koudai; TSUTSUI Takahiro; MURO Yamato; SUGIMOTO Miki; KEMURIYAMA Noriko; SHINOHARA Masami; SASASE Tomohiko; OHTA Takeshi; NAKAE Dai

  Annual Meeting of the Japanese Society of Toxicology, 2021

  
• Effect of high fat diet on kidney in db/db and KK-Ay mice

  YAMAGUCHI Ayane; MIYAJIMA Katsuhiro; UNO Kinuko; SUGIMOTO Miki; KUROKI Fuko; NISHIDA Mei; OGOU Tomoki; KEMURIYAMA Noriko; SHINOHARA Masami; NAKAE Dai; OHTA Takeshi

  Annual Meeting of the Japanese Society of Toxicology, 2020

  
• 新生仔期マウスへのビタミンA補給による腸管、胸腺、脾臓の発育に対する影響の検討

  仲野彰紘; 水永武寿; 太田毅; 杉本実紀

  第70回 関西畜産学会, Oct. 2020

  
• ウシ桑実胚でのヒストンメチル化プロファイリングおよびMAT2Aの寄与の解析

  太田愛里; 池田俊太郎; 篠澤章久; 岩田尚孝; 杉本実紀; 久米新一; 南直治郎; 太田毅

  第70回 関西畜産学会, Oct. 2020

  
• 肥満2型糖尿病モデルSDT fattyラットにおける糖尿病性腎症初期病変の検討

  黒木楓子・杉本実紀・佐野龍平・美谷島克宏・中江大・篠原雅巳・太田毅

  第70回 関西畜産学会, Oct. 2020

  
• ウシ初期胚におけるヒストンメチル化修飾への外因性メチオニンの関与

  太田 愛里; 池田 俊太郎; 杉本 実紀; 南 直治郎; 太田 毅

  The Journal of Reproduction and Development, Sep. 2020

  
• メチレンテトラヒドロ葉酸還元酵素(MTHFR)の胚盤胞発生への寄与について

  石谷 洋希; 池田 俊太郎; 杉本 実紀; 南 直治郎; 太田 毅

  日本生殖医学会雑誌, Apr. 2020

  
• ウシ初期胚のヒストンメチル化におけるメチオニンアデノシルトランスフェラーゼの役割

  太田 愛里; 池田 俊太郎; 杉本 実紀; 南 直治郎; 太田 毅

  The Journal of Reproduction and Development, Sep. 2019

  
• Analysis of SHMT2 function in bovine preimplantation embryos

  ISHITANI Hiroki; IKEDA Shuntaro; SUGIMOTO Miki; KUME Shinichi

  The Journal of Reproduction and Development Supplement, Sep. 2018

  
• Expression of KCNQ1OT1 in bovine preimplantation embryos

  IKEDA Shuntaro; SUGIMOTO Miki; KUME Shinichi

  The Journal of Reproduction and Development Supplement, Sep. 2018

  
• 小児卵胞の体外培養系における必要分子の検討

  奥宮明日香; 寒河江悠介; 上田匡; 谷洋彦; 堀江昭史; 佐藤幸保; 杉本実紀; Brown JB; 万代昌紀

  第36回日本受精着床学会学術講演会, Jul. 2018

  
• 泌乳マウスの小腸と乳腺のIgA 産生に及ぼす水溶性β－カロテンの影響

  村田陸; 杉本実紀; 池田俊太郎; 中辻幸信; 久米新一

  第35回日本微量栄養素学会学術集会, Jun. 2018

  
• 二次卵胞の比較トランスクリプトーム解析に基づいた小児卵胞体外培養系における必要分子の考察

  奥宮 明日香; 寒河江 悠介; 上田 匡; 谷 洋彦; 堀江 昭史; 佐藤 幸保; 杉本 実紀; Brown J.B.; 万代 昌紀

  日本卵子学会誌, Apr. 2018

  
• ウシ初期胚における葉酸サイクル関連酵素の発現動態と機能の解析

  石谷洋希; 池田俊太郎; 杉本実紀; 久米新一

  日本畜産学会第124回大会, Mar. 2018

  
• 簡易かつ高効率なウシ8-16細胞期胚へのsiRNA導入法

  池田 俊太郎; 杉本 実紀; 久米 新一

  日本胚移植学雑誌, Jan. 2018

  
• 黒毛和種繁殖牛と新生子牛の血漿免疫グロブリンに及ぼすβ-カロテンの影響

  石田真穂; 西島嘉隆; 池田俊太郎; 葭谷健一; 小畑敦俊; 杉江勇二; 青木義和; 山路泰介; 藤田雅彦; 中辻幸信; 杉本実紀; 久米新一

  第55回肉用牛研究会大会, Nov. 2017

  
• B vitamin mixture promotes bovine blastocyst development in vitro and downregulates gene expression of TXNIP with epigenetic modification of associated histones

  Ikeda S; Sugimoto M; Kume S

  4th World Congress of Reproductive Biology, Sep. 2017

  
• 黒毛和種繁殖牛の分娩後の血漿免疫グロブリンの変動要因と乾燥ニンジン給与の影響

  石田 真穂; 西島 嘉隆; 谷口 紗耶; 池田 俊太郎; 葭谷 健一; 濱野 貴史; 谷 浩; 藤田 雅彦; 村上 賢司; 小草 啓輔; 佐藤 健史; 杉本 実紀; 久米 新一

  日本畜産学会大会講演要旨集, Mar. 2017

  
• 泌乳マウスの小腸と乳腺におけるIgA 産生に及ぼす乾燥ニンジンの影響

  阪上真優; 池田俊太郎; 杉本実紀; 小草啓輔; 佐藤健史; 久米新一

  第66回関西畜産学会大会, Oct. 2016

  
• β－カロテン不足の黒毛和種牛の初乳中免疫グロブリンに及ぼす乾燥ニンジンの影響

  西島嘉隆; 谷口紗耶; 池田俊太郎; 葭谷健一; 濱野貴史; 谷浩; 藤田雅彦; 村上賢司; 小草啓輔; 佐藤健史; 杉本実紀; 久米新一

  第66回関西畜産学会大会, Oct. 2016

  
• 離乳後マウスと泌乳マウスのIgA産生に及ぼすペプチド亜鉛の影響

  橋本知明; 松山奈央; 杉本実紀; 池田俊太郎; 久米新一

  第33回日本微量栄養素学会学術集会, Jun. 2016

  
• ウシ着床前胚におけるMATの阻害がIGFBP3遺伝子近傍のヒストン修飾に及ぼす影響

  池田 俊太郎; 杉本 実紀; 久米 新一

  日本畜産学会大会講演要旨集, Mar. 2016

  
• 黒毛和種経産牛の分娩前後の血漿成分に及ぼす乾燥ニンジン給与の影響

  谷口紗耶; 王蒙東; 池田俊太郎; 吉岡秀貢; 長瀬祐士; 北村祥子; 糸山恵理奈; 村上弘明; 小草啓輔; 佐藤健史; 杉本実紀; 久米新一

  第65回関西畜産学会大会, Sep. 2015

  
• マウス着床前胚におけるメチオニン依存的なヒストンのメチル化

  工藤 麻里; 池田 俊太郎; 杉本 実紀; 久米 新一

  The Journal of Reproduction and Development, Sep. 2015

  
• ウシ着床前胚におけるメチオニンアデノシルトランスフェラーゼの阻害による遺伝子発現の変化

  池田 俊太郎; 工藤 麻里; 杉本 実紀; 久米 新一

  The Journal of Reproduction and Development, Sep. 2015

  
• 黒毛和種繁殖牛の初乳中免疫グロブリンに及ぼす乾燥ニンジン給与の影響

  谷口 紗耶; 王 蒙東; 池田 俊太郎; 吉岡 秀貢; 長瀬 祐士; 北村 祥子; 糸山 恵理奈; 村上 弘明; 小草 啓輔; 佐藤 健史; 杉本 実紀; 久米 新一

  日本畜産学会大会講演要旨集, Sep. 2015

  
• 離乳後マウスの小腸におけるIgA産生に及ぼすビタミンCの影響

  泉谷紗也佳; 杉本実紀; 池田俊太郎; 久米新一

  第32回日本微量栄養素学会学術集会, May 2015

  
• ウシ着床前胚の発生におけるメチオニンアデノシルトランスフェラーゼの役割

  池田俊太郎; 工藤麻里; 杉本実紀; 久米新一

  日本畜産学会第119回大会, Mar. 2015

  
• マウス着床前胚の発生と細胞系列関連遺伝子の発現制御におけるメチオニンの役割

  工藤麻里; 池田俊太郎; 杉本実紀; 久米新一

  日本畜産学会第119回大会, Mar. 2015

  
• 泌乳マウスのIgGとIgA産生に及ぼす乾燥ニンジンの影響

  阪上真優; 池田俊太郎; 杉本実紀; 久米新一

  日本畜産学会第119回大会, Mar. 2015

  
• 黒毛和種経産牛の初乳中IgGとIgA産生におけるIgMの評価

  谷口紗耶; 王蒙東; 池田俊太郎; 吉岡秀貢; 長瀬祐士; 北村祥子; 糸山恵理奈; 村上弘明; 杉本実紀; 久米新一

  日本畜産学会第119回大会, Mar. 2015

  
• Expression of myo-inositol oxygenase in bovine preimplantation embryos and its regulation by anti-oxidative vitamins

  Ikeda S; Sugimoto M; Kume S

  41st Annual Conference of the International Embryo Transfer Society, Jan. 2015, Peer-reviewed

  
• 黒毛和種経産牛の初乳中免疫グロブリンと脂溶性ビタミンの関係

  王蒙東; 池田俊太郎; 吉岡秀貢; 長瀬祐士; 北村祥子; 糸山恵理奈; 村上弘明; 杉本実紀; 久米新一

  第52回肉用牛研究会京都大会, Sep. 2014

  
• 器官培養マウス新生仔卵巣における卵胞形態に対する培養温度の影響

  杉本実紀; 池田俊太郎; 久米新一

  第64回関西畜産学会大会, Sep. 2014

  
• 黒毛和種経産牛と泌乳マウスの免疫グロブリン産生とビタミンEの関

  王蒙東; 池田俊太郎; 吉岡秀貢; 長瀬祐士; 北村祥子; 糸山恵理奈; 村上弘明; 杉本実紀; 久米新一

  第64回関西畜産学会大会, Sep. 2014

  
• 泌乳マウスの小腸と乳腺のIgA産生に及ぼすβ-クリプトキサンチンの影響

  王蒙東; 杉本実紀; 池田俊太郎; 向井克之; 久米新一

  第31回日本微量栄養素学会学術集会, Jun. 2014

  
• カリウムを多給した高泌乳牛とマウスの分娩前後における水摂取量の評価

  宿院享; 久米新一; 杉本実紀; 池田俊太郎

  日本畜産学会第116回大会, Mar. 2013

  
• 泌乳マウスの増体とIgA産生に及ぼすβ-クリプトキサンチン給与の影響

  王 蒙東; 池田 俊太郎; 杉本 実紀; 向井克之; 久米 新一

  第62回関西畜産学会, Sep. 2012

  
• 妊娠および泌乳期マウスの飲水量と増体に及ぼす塩化カリウム給与の影響

  宿院享; 池田俊太郎; 杉本実紀; 久米新一

  第62回関西畜産学会, Sep. 2012

  
• 器官培養マウス新生仔卵巣に対する培養温度の影響

  杉本実紀; 池田俊太郎; 久米新一

  日本畜産学会大会第115回大会, Mar. 2012

  
• ウシ初期胚におけるアスタキサンチンの暑熱ストレス緩解効果

  黒木 貴久; 池田 俊太郎; 岡田 徹; 眞岡 孝至; 杉本 実紀; 久米 新一

  日本畜産学会第115回大会, Mar. 2012

  
• メチオニン代謝の阻害がウシ体外受精卵の発生に及ぼす影響

  池田俊太郎; 杉本実紀; 久米新一

  第104回日本繁殖生物学会大会, Sep. 2011

  
• 泌乳マウスの乳腺におけるIgA産生に及ぼすクメステロール投与の影響

  王 蒙東; 池田 俊太郎; 杉本 実紀; 久米 新一

  第61回関西畜産学会, Sep. 2011

  
• 暑熱曝露したマウス初期胚に対する葉酸の活性酸素種除去作用

  小山 裕之; 池田 俊太郎; 杉本 実紀; 久米 新一

  第61回関西畜産学会, Sep. 2011

  
• Expression of Glucocorticoid Receptor and Hydroxysteroid 11-beta Dehydrogenases in Bovine Preimplantation Embryos

  Shuntaro Ikeda; Miki Sugimoto; Shinichi Kume

  JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE, Sep. 2011, Peer-reviewed

  
• ウシ孵化前胚におけるグルココルチコイド受容体の発現

  池田俊太郎; 行川貴浩; 杉本実紀; 久米新一

  日本畜産学会大会講演要旨, 28 Mar. 2010

  
• Effects of Coumestrol Administration for Maternal Mice during Pregnancy on Ca Metabolism in Neonatal Mice

  Ueda, M; Horiguchi, Y; Sugimoto, M; Ikeda, S; Kume, S

  The 14th Animal Science Congress of the Asian -Australasian Association of Animal Production Societies, 2010

  
• マウスとウシの卵母細胞および胚盤胞におけるMat1a遺伝子のメチル化解析

  池田俊太郎; 杉本実紀; 久米新一

  第103回日本繁殖生物学会大会, 2010

  
• ウシ初期胚におけるアスタキサンチンの取り込みについて

  黒木 貴久; 行川 貴浩; 池田 俊太郎; 岡田 徹; 杉本 実紀; 久米新一

  第60回関西畜産学会, 2010

  
• マウス初期胚に対する葉酸の暑熱ストレス緩解効果

  小山 裕之; 池田 俊太郎; 杉本 実紀; 久米 新一

  第60回関西畜産学会, 2010

  
• ICR マウスにおける14C 標識シリカ微小粒子を用いた体内動態評価モデルの構築

  今​村​治​世; 坂​井​伸​光; 高​倉​誠​人; 中​山​亜​紀; 米​田​稔; 三​好​弘​一; 杉​本​実​紀; 佐​々​木​克​典; 真​見​一​樹

  第23回日本リスク研究学会年次大会, 2010

  
• アスタキサンチン製剤がウシ初期胚におけるストレス関連遺伝子の発現におよぼす影響

  行川 貴浩; 池田 俊太郎; 杉本 実紀; 久米 新一

  第59回関西畜産学会, 2009

  
• 新生仔マウスのカルシウム代謝に及ぼすクメステロール投与の影響

  上田 道久; 堀口 善裕; 池田 俊太郎; 杉本 実紀; 久米 新一

  第59回関西畜産学会, 2009

  
• 泌乳期マウスへのβカロテン給与が母体および新生仔のIgA産生に及ぼす影響

  西山 佳孝; 池田 俊太郎; 杉本 実紀; 久米 新一

  第59回関西畜産学会, 2009

  
• ブタ黄体の退行における囮受容体(decoy recepter-3)の役割

  眞鍋昇; 高橋創; Wongpanitkannika; 後藤康文; 朴春香; 李俊佑; 杉本実紀; 奥田潔

  第102回日本繁殖生物学会大会, 2009

  
• 核磁気共鳴（NMR）顕微鏡法による蹄壁水分浸透機序の一考察

  杉本 実紀; 桑野 睦敏; 久米 新一; 和田 信也; 冨田 篤志; 吉原 英留

  第22回日本ウマ科学会学術集会, 2009

  
• EXPRESSION OF ENZYMES RELATED TO HOMOCYSTEINE METABOLISM AND HOMOCYSTEINE SENSITIVITY IN BOVINE PREIMPLANTATION EMBRYOS

  S. Ikeda; M. Sugimoto; S. Kume

  REPRODUCTION FERTILITY AND DEVELOPMENT, 2009, Peer-reviewed

  
• Spatial and temporal formation of vimentin filament in bovine post-hatching blastocyst in vitro

  Shuntaro Ikeda; Miki Sugimoto; Shin-ichi Kume

  BIOLOGY OF REPRODUCTION, 2008

  
• ブタ黄体退行における抗アポトーシス因子とアポトーシス因子の役割

  高橋創; 杉本実紀; 奥田潔; 李俊祐; 眞鍋昇

  日本畜産学会第110回大会, 2008

  
• 離乳後のマウスの増体率、窒素出納およびIgA産生に及ぼすホエータンパク質の影響

  高木 菜穂子; 長谷川 清香; 池田 俊太郎; 杉本 実紀; 久米 新一

  第58回関西畜産学会大会, 2008

  
• ウシ初期胚に対する暑熱ストレスの影響とアスタキサンチン製剤による緩解効果

  行川貴浩; 鈴木皓子; 池田俊太郎; 杉本実紀; 久米新一

  第101回日本繁殖生物学会大会, 2008

  
• 塩化カリウム給与がマウスの飲水量,尿量及び窒素出納に与える影響

  MURAI IORI; SUGIMOTO SANENORI; KUME SHIN'ICHI

  日本畜産学会大会講演要旨, 26 Sep. 2007

  
• 妊娠マウスにおけるクメステロール経口投与が,分娩後のビタミンDレセプター,腸型アルカリフォスファターゼ及びその他関連因子に与える影響

  KIRIHATA YUKA; SUGIMOTO SANENORI; KUME SHIN'ICHI

  J Reprod Dev, 25 Sep. 2007

  
• Lectin Dolichos Biflourus Agglutinin (DBA) is a specific marker for primitive germ cells in neonatal porcine testis

  Goel S; Sugimoto M; Kume S; Yamada M; Minami N; Imai H

  33rd International Embryo Transfer Society, 2007, Peer-reviewed

  
• 妊娠後期のマウス胎盤と卵黄嚢におけるオーファン受容体GPRC5Bの局在

  IMANISHI TETSU; KUME SHIN'ICHI; SUGIMOTO MIKI; MANABE NOBORU

  日本獣医学会学術集会講演要旨集, 31 Aug. 2006

  
• Expression of decoy receptor 3 in porcine ovarian follicles.

  M Sugimoto; N Kagawa; N Inoue; M Morita; H Miyamoto; N Manabe

  BIOLOGY OF REPRODUCTION, 2004

  
• Effects of in utero exposure to bisphenol A on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos.

  H Nishizawa; S Imanishi; M Sugimoto; N Manabe

  BIOLOGY OF REPRODUCTION, 2004

  
• Changes in mRNA expression of GPRC5B/Raig2, a novel orphan receptor, in mouse placenta during late gestation

  S Imanishi; N Manabe; M Sugimoto; H Miyamoto

  BIOLOGY OF REPRODUCTION, 2003

  
• NMR spectroscopic assessment of effects of estrogenic compounds on male reproductive organs in mice.

  M Sugimoto; N Manabe; M Morita; K Sezaki; T Tanaka; S Imanishi; H Nishizawa; M Iwahori; H Miyamoto

  BIOLOGY OF REPRODUCTION, 2003

  
• Alterations in mouse uteri induced by maternal administration of diethylstilbestrol.

  M Morita; M Sugimoto; T Tanaka; S Imanishi; N Manabe; H Miyamoto

  BIOLOGY OF REPRODUCTION, 2002

  
• Changes in morphology of mouse oviduct ampulla during early pregnancy.

  M Morita; M Sugimoto; N Manabe; H Miyamoto

  BIOLOGY OF REPRODUCTION, 2001

  
• Changes on morphological properties in mouse oviduct ampulla.

  M Morita; M Sugimoto; N Manabe; H Miyamoto

  BIOLOGY OF REPRODUCTION, 1999

  
• Assessment of the effect of dimethyl sulfoxide on the survival of cryopreserved mouse morulae by single step exposure and rapid freezing

  H Miyamoto; M Sugimoto; T Okuda; Y Takahagi; N Manabe

  THERIOGENOLOGY, Jan. 1998

  
• Development and function of infantile rat ovaries cryopreserved by vitrification.

  M Sugimoto; S Maeda; N Manabe; H Miyamoto

  BIOLOGY OF REPRODUCTION, 1998

  
• Cell proliferation and morphology in oviductal epithelium of cycling mice.

  M Morita; M Sugimoto; N Manabe; H Miyamoto

  BIOLOGY OF REPRODUCTION, 1997

  
• Female reproductive properties, deficiency of luteal cell apoptosis and prenatal development in the senescence accelerated mouse

  H Miyamoto; N Manabe; N Sugimoto; Y Mitani; C Aruga; M Sugimoto

  BIOLOGY OF REPRODUCTION, 1996

  

Presentations

• 卵巣組織の凍結保存

  日本不妊学会シンポジウム（ARTにおける技術革新と限界（動物からヒトへの提言））, 03 Oct. 2002, 日本不妊学会

  

Books and Other Publications

• Morphological alterations in mammalian reproductive organ induced by exposure to diethylstilbestrol (DES).

  Morita, M; Sugimoto, M; Tanaka, T; Imanishi, S; Nishizawa, H; Sezaki, K; Iwahori, M; Manabe, N; Miyamoto, H

  Animal Frontier Science. E. Sato, H. Miyamoto, N. Manabe. Kyoto, Hokuto Pub. Co: 319-323., 2003, Not refereed

  
• Ovarian follicle selection in mammalian ovaries: Regulatory mechanisms of granulosa cell apoptosis during follicular atresia

  Manabe, N; Inoue, N; Miyano, T; Sakamaki, K; Sugimoto, M; Miyamoto, H

  The Ovary P. Leung, E. Adashi. San Diego, Elsevier Academic Press: 369-385., 2003, Not refereed

  
• In vivo and real time estimation of energy metabolism by 31P-nuclear magnetic resonance

  Manabe, N; Azuma, Y; Sugimoto, M; Sezaki, K; Iwahori, M; Imanishi, S; Nishizawa, H; Tanaka, T; Morita, M; Miyamoto, H

  Animal Frontier Science. E. Sato, H. Miyamoto, N. Manabe. Kyoto, Hokuto Pub. Co: 339-347., 2003, Not refereed

  
• Regulatory mechanisms of follicle selection in mammalian ovaries

  Manabe, N; Inoue, N; Matsui, T; Nakagawa, S; Maeda, A; Miyano, T; Sakamaki, K; Sugimoto, M; Miyamoto, H

  Animal Frontier Science. E. Sato, H. Miyamoto, N. Manabe. Kyoto, Hokuto Pub. Co: 117-132., 2003, Not refereed

  
• Utilization of magnetic resonance microscope for studies in reproductive toxicology

  Sugimoto, M; Manabe, N; Morita, M; Sezaki, K; Tanaka, T; Imanishi, S; Nishizawa, H; Iwahori, M; Miyamoto, H

  Animal Frontier Science. E. Sato, H. Miyamoto, N. Manabe. Kyoto, Hokuto Pub. Co: 325-330., 2003, Not refereed

  
• Utilization of NMR microscopy in developmental toxicology: Assessment of mouse embryo malformations induced by maternal administration of retinoic acid

  Sugimoto, M; Manabe, N; Morita, M; Tanaka, T; Okamoto, R; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 177-181., 2001, Not refereed

  
• Basic aspects of organ cryopreservation and application for preservation of mammalian ovarian tissue

  Sugimoto, M; Manabe, N; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 341-346., 2001, Not refereed

  
• Functions of mammalian oviducts and their relevance to morphology

  Morita, M; Sugimoto, M; Manabe, N; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 127-131., 2001, Not refereed

  
• Effects of endocrine disrupters on the expression of nuclear receptors in murine embryos

  Tanaka, T; Manabe, N; Okamoto, R; Sugimoto, M; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 183-188., 2001, Not refereed

  
• Teratosis induced by retinoids relates to apoptotic cell death in mouse embryos

  Manabe, N; Okuda, T; Sugimoto, M; Tanaka, T; Okamoto, R; Kiso, M; Komatsu, K; Yamaguchi, M; Yamada-Uchio, K; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 167-176., 2001, Not refereed

  
• 卵子の応用（臨床）技術・卵子の凍結保存法・卵巣組織片

  宮本元; 杉本実紀

  卵子研究法. 鈴木秋悦, 佐藤英明. 東京, 養賢堂. 2001: 311−315., 2001, Not refereed

  
• In vivo 31P-nuclear magnetic resonance technique for estimation of liver energy metabolism in mice

  Manabe, N; Azuma, Y; Sugimoto, M; Yamaguchi, M; Yamada-Uchio, K; Komatsu, K; Kiso, M; Tanaka, T; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 405-413., 2001, Not refereed

  
• Histological and biochemical profiles of granulosa cell apoptosis in follicular atresia of porcine ovaries

  Manabe, N; Sugimoto, M; Nakayama, M; Inoue, N; Matsui, T; Yamaguchi, M; Yamada-Uchio, K; Miyamoto, H

  Reproductive biotechnology: reproductive biotechnology update and its related physiology H. Miyamoto, N. Manabe. Kyoto, Hokuto Shobo: 61-72., 2001, Not refereed

  
• Regulatory mechanisms of granulosa cell apoptosis in ovarian follicle atresia: Role of granulosa cell apoptosis in porcine ovarian follicle atresia

  Manabe, N; Kimura, Y; Uchio, K; Tajima, C; Matsushita, H; Nakayama, M; Sugimoto, M; Miyamoto, H

  Animal cell technology : challenges for the 21st century. K. Iikura, M. Nagao, S. Masuda, R. Sasaki. Dordrecht, Kluwer: 343-347., 1999, Not refereed

  
• Granulosa cell glycoconjugates found in atretic follicles of the pig ovary

  Kimura, Y; Manabe, N; Matushita, H; Imai, Y; Sugimoto, M; Miyamoto, H

  Reproductive biology update: Novel tools for assessment of environmental toxicity. H. Miyamoto, N. Manabe. Kyoto, Shoukadou Booksellers: 59-66., 1998, Not refereed

  
• The morphology of mammalian oviductal epithelium and its functional relevance

  Morita, M; Sugimoto, M; Manabe, N; Miyamoto, H

  Reproductive biology update: Novel tools for assessment of environmental toxicity. H. Miyamoto, N. Manabe. Kyoto, Shoukadou Booksellers: 337-343., 1998, Not refereed

  
• Retinoids induce malformations related to cell death in mouse embryos

  Manabe, N; Okuda, T; Takakuwa, H; Sugimoto, M; Miyamoto, H

  Reproductive biology update: Novel tools for assessment of environmental toxicity. H. Miyamoto, N. Manabe. Kyoto, Shoukadou Booksellers: 365-374., 1998, Not refereed

  
• Organ cryopreservation of mammalian ovarian tissue as a means for preservation of female germ cells and ovarian endocrine function

  Sugimoto, M; Kabasawa, T; Maeda, S; Manabe, N; Miyamoto, H

  Reproductive biology update: Novel tools for assessment of environmental toxicity. H. Miyamoto, N. Manabe. Kyoto, Shoukadou Booksellers: 439-448., 1998, Not refereed

  
• Role of granulosa cell apoptosis in ovarian follicle atresia

  Manabe, N; Kimura, Y; Myoumoto, A; Matsushita, H; Tajima, C; Sugimoto, M; Miyamoto, H

  Apoptosis : its roles and mechanism. T. Yamada, Y. Hashimoto. Tokyo, Business Center for Academic Societies Japan: 97-111., 1998, Not refereed

  
• Regulatory mechanisms of granulosa cell apoptosis in porcine ovarian follicle atresia

  Manabe, N; Myoumoto, A; Kimura, Y; Imai, Y; Sugimoto, M; Sakamaki, K; Okamura, Y; Fukumoto, M; Miyamoto, H

  Reproductive biology update: Novel tools for assessment of environmental toxicity. H. Miyamoto, N. Manabe. Kyoto, Shoukadou Booksellers: 23-35., 1998, Not refereed

  
• A Monoclonal antibodiy against pig ovarian follicular granulosa cells recognizes a novel cell death receptor and induces granulosa cell apoptosis

  Manabe, N; Myoumoto, A; Kimura, Y; Imai, Y; Sugimoto, M; Miyamoto, H

  Advances in comparative endocrinology. S. Kawashima, S. Kikuyama. Bologna, Monduzzi Editore: 1793-1797., 1997, Not refereed

  
• Female reproductive characteristics of the senescence accelerated mouse

  Miyamoto, H; Manabe, N; Watanabe, T; Aruga, C; Mitani, Y; Sugimoto, N; Sugimoto, M; Sato, E

  The SAM model of senescence. T. Takeda. Amsterdam, Elsevier Science Publishers: 279-282., 1994, Not refereed

  
• Quantitative studies on spermatogenesis in the senescence accelerated mouse

  Miyamoto, H; Manabe, N; Akiyama, Y; Sugimoto, M; Sato, E

  The SAM model of senescence. T. Takeda. Amsterdam, Elsevier Science Publishers: 275-278., 1994, Not refereed

  

Industrial Property Rights

• 特許5410782, 特開2010-187629, 特願2009-037625号, 人工受精用培地組成物

  行川 貴浩; 鈴木 皓子; 池田 俊太郎; 杉本 実紀; 久米 新一

  
• 特許3694730, 特開2010-187629, 特願2009-037625, 組織の冷却保存液

  宮本 元; 杉本 実紀; 眞鍋 昇

  

Awards

• 31 Jul. 2017

  日本学術振興会, H28年度特別研究員等審査会専門委員（書面担当）の表彰

External funds: Kakenhi

• 長期維持型卵胞の形成増強法の開発および卵胞動態制御への影響の解析

  Grant-in-Aid for Scientific Research (C)

  Basic Section 42010:Animal production science-related

  Kyoto University

  杉本 実紀

  From 01 Apr. 2021, To 31 Mar. 2025, Granted

  卵巣;哺乳類;雌;生殖寿命;卵胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K05906/
• Development of a new in vitro culture system in secondary follicles of human children.

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields

  Kyoto University

  伊藤 美幸

  From 29 Jun. 2018, To 31 Mar. 2020, Discontinued

  未熟卵子;マウス二次卵胞;Figla;がん生殖;卵子体外培養;RNAシークエンス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K19613/
• 長期維持型卵胞の形成増強法の開発と卵巣機能への影響の解析

  Grant-in-Aid for Scientific Research (C)

  Basic Section 42010:Animal production science-related

  Kyoto University

  杉本 実紀

  From 01 Apr. 2018, To 31 Mar. 2024, Granted

  哺乳類;卵巣;卵胞;雌;生殖;生殖寿命

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K05944/
• Studies on the enhancement of reserved-type follicle formation for extension of the female reproductive lifespan

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Miki Sugimoto

  From 01 Apr. 2015, To 31 Mar. 2019, Project Closed

  哺乳類;卵巣;卵胞;雌;生殖;生殖寿命;哺乳動物;応用動物;畜産学;細胞・組織;発生・分化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K14877/
• Nutriepigenetics in mammalian preimplantation embryos

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Shuntaro Ikeda

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  エピジェネティクス;ニュートリエピジェネティクス;初期胚;着床前胚;ウシ;One-carbon metabolism;受精卵

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K07779/
• Evaluation of nanoparticles exposure from surrounding environment and study on their disposition

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Minoru YONEDA

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  ナノシリカ粒子;体内動態;PBPPKモデル;動物実験;空気中濃度;PBPKモデル;気管内投与;尾静脈投与;単回投与;連続投与;リスク評価;静脈内投与;排泄経路;粒径分布;ICR-マウス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21360253/
• Effects of dietary methyl donors on development and epigenetics of bovine preimplantation embryos

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Shuntaro IKEDA

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  栄養と繁殖;メチル基栄養;ウシ;初期胚;エピジェネティクス;着床前胚;飼料性メチル基供与体;エピジェネティク;メチル化;家畜;胚盤胞;発生;分化;メチル基供与体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19780209/
• Development of Cryopresservation technique for ovarian germline stem cells

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Miki SUGIMOTO

  From 01 Apr. 2005, To 31 Mar. 2008, Project Closed

  哺乳動物;雌性生殖器系;卵巣;生殖細胞;幹細胞, Mammals;Female Reproductive Organs;Ovary;Germ cell;Stem cells

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17580254/
• Real-time assessment technique for reproductive toxicity of environmental disruptors by nuclear magnetic resonance microscopy

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hajime MIYAMOTO

  From 01 Apr. 2002, To 31 Mar. 2004, Project Closed

  外因性内分泌攪乱物質;核磁気共鳴イメージング;三次元形態解析;哺乳類;胎仔;オーファン受容体;受容体ノックアウト;リアルタイム解析;外因性内分泌撹乱物質, environmental disruptors;magnetic resonance imaging;3D-morphoanalysis;mammal;embryo;orphan receptor;receptor nock out;real-time assessment

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14360167/
• 哺乳類卵胞の選択的死滅制御機構とその人為支配による潜在的卵巣卵の利用

  Grant-in-Aid for Creative Scientific Research

  The University of Tokyo;Kyoto University

  眞鍋 昇

  From 01 Apr. 2001, To 31 Mar. 2006, Project Closed

  哺乳類;卵巣;卵胞;選択的死滅;アポトーシス;細胞死受容体;細胞内シグナル伝達阻害因子;異種移植;カスパーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13GS0008/
• 核磁気共鳴顕微鏡法による細胞死の生体内解析

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  杉本 実紀

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  核磁気共鳴法;磁気共鳴画像法;磁気共鳴顕微鏡法;組織傷害;核磁気共鳴画像;細胞死

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13760198/
• 内分泌攪乱物質による生殖毒性評価システムの構築:構造生物学・細胞生物学的リアルタイム評価法の確立

  Grant-in-Aid for Scientific Research on Priority Areas

  Science and Engineering

  Kyoto University

  宮本 元;眞鍋 昇

  From 01 Apr. 2001, To 31 Mar. 2004, Project Closed

  外因性内分泌攪乱物質;核磁気共鳴イメージング;三次元形態解析;哺乳類;胎仔;オーファン受容体;受容体ノックアウト;リアルタイム解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13027241/
• Development of an efficient system for cryopreservation of oocytes and embryos by use of ultrarapid vitrification

  Grant-in-Aid for Scientific Research (B)

  Kochi University

  Magosaburo KASAI

  From 01 Apr. 2000, To 31 Mar. 2003, Project Closed

  受精卵;胚;卵母細胞;凍結細胞;ガラス化;卵巣;チャンネル;耐凍剤;凍結保存;透過性;水チャンネル, embryo;oocyte;cryopreservation;vitrification;ovary;channel;cryoprotectant

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12460126/
• 選択的卵胞閉鎖の分子制御機構の解明とその人為支配

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  眞鍋 昇

  From 01 Apr. 2000, To 31 Mar. 2003, Project Closed

  アポトーシス;卵胞;細胞死受容体;デコイ受容体;HVJ-リポソーム;遺伝子導入;モノクローナル抗体;ブタ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12460125/
• Non-invasive assessment for teratogenic-toxicity of environmental disrupters by structural- and cel lurar-biological methods

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Noboru MANABE

  From 01 Apr. 1999, To 31 Mar. 2002, Project Closed

  環境ホルモン;生殖毒性;遺伝毒性;食物連鎖;胎児奇形;生殖生理学;生殖腺;構造生物学;生体核磁気共鳴装置;外因性内分泌攪乱物質;ステロイドホルモン;オーファン受容体;ステロイドホルモン受容体;哺乳類生殖子;哺乳類胎児;催奇形性, environmental distruptors;reproductive toxicity;genetic toxicity;food chain;embryionic teratogenecity;reproductive physiology;genital gland;structural biology

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11556052/
• Regulation mechanisms of germinal cell selection in mammals and its artificial control

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hajime MIYAMOTO

  From 01 Apr. 1999, To 31 Mar. 2002, Project Closed

  卵巣;卵胞;顆粒層細胞;哺乳類;アポトーシス;細胞死受容体;モノクローナル抗体;プログラム細胞死;アポトーシス受容体;デコイ受容体;HVJ-リポソーム;遺伝子導入;ブタ;モノクロナール抗体, Ovary;Follicle;Granulosa cell;Mammal;Apoptosis;Cell-death receptor;Monoclonal antibody;Programmed cell death

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11460127/
• 冬眠哺乳動物の低温耐性因子の探索および器官低温保存への利用

  Grant-in-Aid for Encouragement of Young Scientists (A)

  Kyoto University

  杉本 実紀

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  冬眠;低温適応;低温保存

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10760163/
• Regulatory mechanisms of granulosa cell apoptosis in porcine ovarian follicle atresia

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Hajime MIYAMOTO

  From 01 Apr. 1996, To 31 Mar. 1999, Project Closed

  卵巣;卵胞;顆粒層細胞;アポトーシス;細胞死受容体;ブタ;モノクローナル抗体;プログラム細胞死;カスパーゼ様プロテアーゼ;受容体分子;モノクロナール抗体;卵丘細胞;卵胞閉鎖;家畜, Ovary;Follicle;Granulosa cell;Apoptosis;Cell death receptor;Porcine;Monoclonal antibody;Porgram cell death

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08456141/
• 核磁気共鳴法(NMR)による生体構成成分と凍害保護物質の相互作用の解析法の開発

  Grant-in-Aid for Encouragement of Young Scientists (A)

  Kyoto University

  杉本 実紀

  From 01 Apr. 1995, To 31 Mar. 1996, Project Closed

  凍害保護物質;凍結保存;低温保存;NMR;MRI;dimethylsulfoxide

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07760266/

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Animal Physiology and Anatomy

  DF15, Spring, Graduate School of Agriculture, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Animal Physiology and Anatomy

  DF15, Fall, Graduate School of Agriculture, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Course in Animal Science II

  5363, Fall, Faculty of Agriculture, 6
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Course in Animal Science I

  5361, Spring, Faculty of Agriculture, 6
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Course in Animal Physiology and Anatomy

  DG15, Spring, Graduate School of Agriculture, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Course in Animal Physiology and Anatomy

  DG15, Fall, Graduate School of Agriculture, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar for Applied Animal Science I

  5293, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Practical Course in Applied Animal Science II

  1046, Spring, Faculty of Agriculture, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Animal Science

  5699, Spring, Faculty of Agriculture, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Foreign Literature in Animal Science II

  5387, Fall, Faculty of Agriculture, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar for Applied Animal Science II

  5295, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Course in Animal Science II

  5363, Fall, 農学部
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Course in Animal Science I

  5361, Spring, 農学部
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Animal Physiology and Anatomy2

  DB35, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Animal Physiology and Anatomy1

  DB34, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Course in Animal Physiology and Anatomy2

  DC35, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Course in Animal Physiology and Anatomy1

  DC34, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar for Applied Animal Science II

  5295, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar for Applied Animal Science I

  5293, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Practical Course in Applied Animal Science II

  1046, Spring, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Animal Science

  5699, Spring, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Foreign Literature in Animal Science II

  5387, Fall, Faculty of Agriculture, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Animal Physiology and Anatomy

  DA29, Fall, Graduate School of Agriculture, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Practical Course in Applied Animal Science II

  1046, Spring, Faculty of Agriculture, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar for Applied Animal Science I

  5293, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar for Applied Animal Science II

  5295, Year-long, Faculty of Agriculture, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Animal Physiology and Anatomy2

  DB35, Year-long, Graduate School of Agriculture, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Course in Animal Physiology and Anatomy2

  DC35, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Course in Animal Physiology and Anatomy1

  DC34, Year-long, Graduate School of Agriculture, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Animal Physiology and Anatomy1

  DB34, Year-long, Graduate School of Agriculture, 3
• From Apr. 2011, To Mar. 2012

  応用動物科学演習I

  Year-long, 農学部
• From Apr. 2011, To Mar. 2012

  応用動物科学演習II

  Year-long, 農学部
• From Apr. 2011, To Mar. 2012

  生体機構学専攻実験

  農学研究科
• From Apr. 2011, To Mar. 2012

  生体機構学演習

  農学研究科
• From Apr. 2011, To Mar. 2012

  生体機構学特論

  農学研究科
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Course in Bioresource Science I

  5195, Spring, 農学部
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Course in Bioresource Science II

  5197, Fall, 農学部
• 資源生物科学基礎実験
• 資源生物科学専門外書講義I
• From Apr. 2012, To Mar. 2013

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2012, To Mar. 2013

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2013, To Mar. 2014

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2013, To Mar. 2014

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2013, To Mar. 2014

  Animal Physiology and Anatomy

  Fall, 農学研究科
• From Apr. 2013, To Mar. 2014

  Seminar in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2013, To Mar. 2014

  Laboratory Course in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2014, To Mar. 2015

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2014, To Mar. 2015

  Seminar in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Course in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2015, To Mar. 2016

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2015, To Mar. 2016

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Course in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2015, To Mar. 2016

  Animal Physiology and Anatomy

  Fall, 農学研究科
• From Apr. 2015, To Mar. 2016

  Introduction to Foreign Literature in Bioresource Science I

  Spring, 農学部
• From Apr. 2016, To Mar. 2017

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2016, To Mar. 2017

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2016, To Mar. 2017

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Laboratory Course in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Physiology

  Spring, 農学部
• From Apr. 2017, To Mar. 2018

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2017, To Mar. 2018

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2017, To Mar. 2018

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory Course in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Animal Physiology and Anatomy

  Year-long, 農学研究科
• From Apr. 2017, To Mar. 2018

  Animal Physiology and Anatomy

  Fall, 農学研究科
• From Apr. 2018, To Mar. 2019

  Physiology

  Spring, 農学部
• From Apr. 2018, To Mar. 2019

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2018, To Mar. 2019

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2018, To Mar. 2019

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2018, To Mar. 2019

  Introduction to Foreign Literature in Bioresource Science II

  Fall, 農学部
• From Apr. 2019, To Mar. 2020

  Physiology

  Spring, 農学部
• From Apr. 2019, To Mar. 2020

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2019, To Mar. 2020

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2019, To Mar. 2020

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2019, To Mar. 2020

  Animal Physiology and Anatomy

  Fall, 農学研究科
• From Apr. 2019, To Mar. 2020

  Introduction to Foreign Literature in Bioresource Science II

  Fall, 農学部
• From Apr. 2020, To Mar. 2021

  Physiology

  Spring, 農学部
• From Apr. 2020, To Mar. 2021

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2020, To Mar. 2021

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2020, To Mar. 2021

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2020, To Mar. 2021

  Introduction to Foreign Literature in Bioresource Science I

  Spring, 農学部
• From Apr. 2021, To Mar. 2022

  Physiology

  Spring, 農学部
• From Apr. 2021, To Mar. 2022

  Seminar for Applied Animal Science II

  Year-long, 農学部
• From Apr. 2021, To Mar. 2022

  Seminar for Applied Animal Science I

  Year-long, 農学部
• From Apr. 2021, To Mar. 2022

  Laboratory Course in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Laboratory Course in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Animal Physiology and Anatomy1

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Animal Physiology and Anatomy2

  Year-long, 農学研究科
• From Apr. 2021, To Mar. 2022

  Animal Physiology and Anatomy

  Fall, 農学研究科
• From Apr. 2021, To Mar. 2022

  Introduction to Foreign Literature in Bioresource Science I

  Spring, 農学部

Administration

Faculty management (title, position)

• From 01 Apr. 2005, To 31 Mar. 2025

  動物実験委員会　委員
• From 01 Apr. 2012, To 31 Mar. 2014

  農学研究科衛生管理者
• From 01 Apr. 2012, To 31 Mar. 2014

  環境・安全・衛生委員会委員
• From 01 Apr. 2019, To 31 Mar. 2021

  国際交流委員会　委員

Academic, Social Contribution

Academic Contribution

• 科学研究費審査委員

  Supervision (editorial)

  日本学術振興会, From 15 Jun. 2020, To 30 Nov. 2020

  
• -

  Other

  -, From 01 Apr. 2009, To 31 Mar. 2010

  
• -

  Other

  -, From 01 Jun. 2006, To 31 Mar. 2010

  

Social Contribution

• -

  Other

  -, From 22 Aug. 2020, To 22 Aug. 2020

  
• -

  Other

  -, From 01 Aug. 2015, To 31 Jul. 2017

  
• -

  Other

  -, From 01 Dec. 2012, To 30 Nov. 2014