Basic Information

Affiliated programs (koza)

• Graduate School of Medicine, 医学専攻 放射線システム生物学, 講師
• Graduate School of Medicine, 医科学専攻 放射線システム生物学, 講師

Academic Degree

• 修士（理学）(京都大学)
• 博士（理学）(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院理学研究科博士後期課程生物科学専攻, 修了
• 京都大学, 大学院理学研究科修士課程生物科学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 理学部生物物理学科, 卒業

Research History

• From 2012

  京都大学 放射線生物研究センター, 講師

Profile

• Profile

  京都大学理学研究科卒業後、渡英。サセックスの自由な空気のもとDNA損傷研究に打ち込み、、遺伝研、京大と今に至る。

Language of Instruction

• English
• Japanese

ID,URL

• J-Global ID

  201301039818462039

• Researcher number

  90455204

• External link

  http://kaken.nii.ac.jp/d/r/90455204.ja.html

Website(s) (URL(s))

• http://www.rbc.kyoto-u.ac.jp

researchmap URL

• https://researchmap.jp/kfuruya

Research

Research Topics, Overview of the research

• Research Topics

  Cell proliferation control under genotoxic stress

• Overview of the research

  Our cells is constantly under the threat of DNA damage stress. The first step of DNA damage response is efficient detection of DNA damage, Since we found that the feedback system of DNA damage detection system that promote rapid inactivation after the activation of DNA damage response. Our final aim is to understand the molecular nature of the feedback system and uncover the universal nature of the feedback regulation at the stress responses.

Research Interests

• バイオイメージング
• 細胞周期
• DDK
• チェックポイント
• DNA損傷
• 環境応答
• DNA修復
• Rad9
• 細胞内情報伝達
• リン酸化
• 染色体
• 分配
• DNA結合
• 細胞分裂
• 無核

Research Areas

• Life sciences, Molecular biology
• Environmental science/Agricultural science, Environmental effects of chemicals
• Environmental science/Agricultural science, Environmental effects of radiation

Papers

• 異分野融合研究の醍醐味:揺らぎ、振動、バラツキに視点をおいた生命科学研究の新たな到達点 予測不可能なゲノム損傷に対応する多様なヒストン化学修飾の役割とその頑強性

  井倉 毅; 古谷 寛治; 白木 琢磨; 井倉 正枝

  日本生化学会大会プログラム・講演要旨集, Nov. 2022

  
• 細胞のロバストネスを規定するタンパク質複合体のダイナミクス DNA損傷応答におけるヒストンH2AX複合体モジュールのダイナミクス

  井倉 毅; 古谷 寛治; 白木 琢磨; 井倉 正枝

  日本生化学会大会プログラム・講演要旨集, Sep. 2016

  
• E‐cadherin‐dependent coordinated epithelial rotation on a two‐dimensional discoidal pattern

  Shuangyu Luo; Kanji Furuya; Kimiya Matsuda; Yuma Tsukasa; Tadao Usui; Tadashi Uemura

  Genes to Cells, 30 Dec. 2022

  
• Machine learning extracts oncogenic‐specific γ‐H2AX foci formation pattern upon genotoxic stress

  Kanji Furuya; Masae Ikura; Tsuyoshi Ikura

  Genes to Cells, 03 Jan. 2023

  
• Impact of Nuclear De Novo NAD+ Synthesis via Histone Dynamics on DNA Repair during Cellular Senescence To Prevent Tumorigenesis

  Masae Ikura; Kanji Furuya (equally conributed 1st); Tomonari Matusda; Tsuyoshi Ikura

  Molecular and Cellular Biology, Oct. 2022, Peer-reviewed, Lead author

  
• Epigenetic interplays between DNA demethylation and histone methylation for protecting oncogenesis.

  Kanji Furuya; Masae Ikura; Tsuyoshi Ikura

  J Biochemistry, Apr. 2019, Peer-reviewed, Invited

  
• The Ras1-Cdc42 pathway is involved in hyphal development of Schizosaccharomyces japonicus

  Shingo Nozaki; Kanji Furuya; Hironori Niki

  FEMS Yeast Research, Mar. 2018, Peer-reviewed

  
• Body-spiritual alteration in life science

  古谷寛治

  身心変容と霊的暴力 年報, Mar. 2018

  
• 生命科学からみた身心変容

  古谷寛治

  身心変容と霊的暴力 年報, Mar. 2018

  
• Schizosaccharomyces Japonicus: A distinct dimorphic yeast among the fission yeasts

  Keita Aoki; Kanji Furuya; Hironori Niki

  Cold Spring Harbor Protocols, 01 Dec. 2017, Peer-reviewed

  
• Mating, spore dissection, and selection of diploid cells in Schizosaccharomyces Japonicus

  Kanji Furuya; Hironori Niki

  Cold Spring Harbor Protocols, 01 Dec. 2017, Peer-reviewed, Invited

  
• The CDK-PLK1 axis targets the DNA damage checkpoint sensor protein RAD9 to promote cell proliferation and tolerance to genotoxic stress

  Takeshi Wakida; Masae Ikura; Kenji Kuriya; Shinji Ito; Yoshiharu Shiroiwa; Toshiyuki Habu; Takuo Kawamoto; Katsuzumi Okumura; Tsuyoshi Ikura; Kanji Furuya

  ELIFE, Dec. 2017, Peer-reviewed

  
• 分子生物学的視点から見た外的ストレスと恒常性維持

  古谷寛治

  身心変容技法研究, Mar. 2017, Invited

  
• Coordinated Regulation of TIP60 and Poly(ADP-Ribose) Polymerase 1 in Damaged-Chromatin Dynamics

  Masae Ikura; Kanji Furuya; Atsuhiko Fukuto; Ryo Matsuda; Jun Adachi; Tomonari Matsuda; Akira Kakizuka; Tsuyoshi Ikura

  MOLECULAR AND CELLULAR BIOLOGY, May 2016, Peer-reviewed

  
• Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin

  Masae Ikura; Kanji Furuya; Shun Matsuda; Ryo Matsuda; Hiroki Shima; Jun Adachi; Tomonari Matsuda; Takuma Shiraki; Tsuyoshi Ikura

  MOLECULAR AND CELLULAR BIOLOGY, Dec. 2015, Peer-reviewed

  
• Absolute quantification of acetylation and phosphorylation of the histone variant H2AX upon ionizing radiation reveals distinct cellular responses in two cancer cell lines

  Shun Matsuda; Kanji Furuya; Masae Ikura; Tomonari Matsuda; Tsuyoshi Ikura

  RADIATION AND ENVIRONMENTAL BIOPHYSICS, Nov. 2015, Peer-reviewed

  
• 論考“科学教育と科学研究”

  古谷寛治

  こころの未来, Jun. 2014

  
• Synchronous activation of cell division by light or temperature stimuli in the dimorphic yeast Schizosaccharomyces japonicus

  Sho Okamoto; Kanji Furuya; Shingo Nozaki; Keita Aoki; Hironori Niki

  Eukaryotic Cell, Sep. 2013, Peer-reviewed

  
• Hyphal differentiation induced via a DNA damage checkpoint-dependent pathway engaged in crosstalk with nutrient stress signaling in Schizosaccharomyces japonicus

  Kanji Furuya; Hironori Niki

  CURRENT GENETICS, Dec. 2012, Peer-reviewed

  
• Construction of an insertion marker collection of Sz. japonicus (IMACS) for genetic mapping and a fosmid library covering its genome

  Kanji Furuya; Keita Aoki; Hironori Niki

  YEAST, Jun. 2012, Peer-reviewed

  
• Phosphorylated Rad9 is released from damaged chromatin

  Kanji Furuya

  Seikagaku, 2012, Peer-reviewed

  
• Construction of diploid zygotes by interallelic complementation of ade6 in Schizosaccharomyces japonicus

  Kanji Furuya; Hironori Niki

  YEAST, Oct. 2011, Peer-reviewed

  
• Breakage of the nuclear envelope by an extending mitotic nucleus occurs during anaphase in Schizosaccharomyces japonicus

  Keita Aoki; Hanako Hayashi; Kanji Furuya; Mamiko Sato; Tomoko Takagi; Masako Osumi; Akatsuki Kimura; Hironori Niki

  GENES TO CELLS, Sep. 2011, Peer-reviewed

  
• Comparative Functional Genomics of the Fission Yeasts

  Nicholas Rhind; Zehua Chen; Moran Yassour; Dawn A. Thompson; Brian J. Haas; Naomi Habib; Ilan Wapinski; Sushmita Roy; Michael F. Lin; David I. Heiman; Sarah K. Young; Kanji Furuya; Yabin Guo; Alison Pidoux; Huei Mei Chen; Barbara Robbertse; Jonathan M. Goldberg; Keita Aoki; Elizabeth H. Bayne; Aaron M. Berlin; Christopher A. Desjardins; Edward Dobbs; Livio Dukaj; Lin Fan; Michael G. FitzGerald; Courtney French; Sharvari Gujja; Klavs Hansen; Dan Keifenheim; Joshua Z. Levin; Rebecca A. Mosher; Carolin A. Mueller; Jenna Pfiffner; Margaret Priest; Carsten Russ; Agata Smialowska; Peter Swoboda; Sean M. Sykes; Matthew Vaughn; Sonya Vengrova; Ryan Yoder; Qiandong Zeng; Robin Allshire; David Baulcombe; Bruce W. Birren; William Brown; Karl Ekwall; Manolis Kellis; Janet Leatherwood; Henry Levin; Hanah Margalit; Rob Martienssen; Conrad A. Nieduszynski; Joseph W. Spatafora; Nir Friedman; Jacob Z. Dalgaard; Peter Baumann; Hironori Niki; Aviv Regev; Chad Nusbaum

  SCIENCE, May 2011, Peer-reviewed

  
• Novel episomal vectors and a highly efficient transformation procedure for the fission yeast Schizosaccharomyces japonicus

  Keita Aoki; Reiko Nakajima; Kanji Furuya; Hironori Niki

  YEAST, Dec. 2010, Peer-reviewed

  
• DDK Phosphorylates Checkpoint Clamp Component Rad9 and Promotes Its Release from Damaged Chromatin

  Kanji Furuya; Izumi Miyabe; Yasuhiro Tsutsui; Francesca Paderi; Naoko Kakusho; Hisao Masai; Hironori Niki; Antony M. Carr

  MOLECULAR CELL, Nov. 2010, Peer-reviewed

  
• The DNA Damage Checkpoint Regulates a Transition between Yeast and Hyphal Growth in Schizosaccharomyces japonicus

  Kanji Furuya; Hironori Niki

  MOLECULAR AND CELLULAR BIOLOGY, Jun. 2010, Peer-reviewed

  
• Isolation of heterothallic haploid and auxotrophic mutants of Schizosaccharomyces japonicus.

  Furuya K; Niki H

  Yeast (Chichester, England), Apr. 2009, Peer-reviewed

  
• Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin

  Yuu Kimata; Akihisa Matsuyama; Koji Nagao; Kanji Furuya; Chikashi Obuse; Minoru Yoshida; Mitsuhiro Yanagida

  JOURNAL OF CELL SCIENCE, Apr. 2008, Peer-reviewed

  
• Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice

  Mihoko Kai; Kanji Furuya; Francesca Paderi; Antony M. Carr; Teresa S. F. Wang

  NATURE CELL BIOLOGY, Jun. 2007, Peer-reviewed

  
• Postreplication repair and PCNA modification in Schizosaccharomyces pombe

  Jonathan Frampton; Anja Irmisch; Catherine M. Green; Andrea Neiss; Michelle Trickey; Helle D. Ulrich; Kanji Furuya; Felicity Z. Watts; Antony M. Carr; Alan R. Lehmann

  MOLECULAR BIOLOGY OF THE CELL, Jul. 2006, Peer-reviewed

  
• Identification and functional analysis of TopBP1 and its homologs

  Garcia, V; K Furuya; AM Carr

  DNA REPAIR, Nov. 2005, Peer-reviewed

  
• Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BCRT domains of Rad4(TOPBP1)

  K Furuya; M Poitelea; L Guo; T Caspari; AM Carr

  GENES & DEVELOPMENT, May 2004, Peer-reviewed

  
• DNA checkpoints in fission yeast

  K Furuya; AM Carr

  JOURNAL OF CELL SCIENCE, Oct. 2003, Peer-reviewed

  
• Control of localization of a spindle checkpoint protein, Mad2, in fission yeast

  AE Ikui; K Furuya; M Yanagida; T Matsumoto

  JOURNAL OF CELL SCIENCE, Apr. 2002, Peer-reviewed

  
• Requirement of chromatid cohesion proteins Rad21/Scc1 and Mis4/Scc2 for normal spindle-kinetochore interaction in fission yeast

  Y Toyoda; K Furuya; G Goshima; K Nagao; K Takahashi; M Yanagida

  CURRENT BIOLOGY, Mar. 2002, Peer-reviewed

  
• Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase

  T Tomonaga; K Nagao; Y Kawasaki; K Furuya; A Murakami; J Morishita; T Yuasa; T Sutani; SE Kearsey; F Uhlmann; K Nasmyth; M Yanagida

  GENES & DEVELOPMENT, Nov. 2000, Peer-reviewed

  
• Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase

  K Tanaka; T Yonekawa; Y Kawasaki; M Kai; K Furuya; M Iwasaki; H Murakami; M Yanagida; H Okayama

  MOLECULAR AND CELLULAR BIOLOGY, May 2000, Peer-reviewed

  
• Faithful anaphase is ensured by Mis4, a sister chromatid cohesion molecule required in S phase and not destroyed in G(1) phase

  K Furuya; K Takahashi; M Yanagida

  GENES & DEVELOPMENT, Nov. 1998, Peer-reviewed

  

Misc.

• 予測不可能なゲノム損傷に対応する多様なヒストン化学修飾の役割とその頑強性

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本生化学会大会(Web), 2022

  
• ゲノムストレス応答の多様性を数理的アプローチで理解する

  井倉毅; 白木琢磨; 古谷寛治; 井倉正枝

  日本分子生物学会年会プログラム・要旨集(Web), 2016

  
• ジャポニカス分裂酵母菌を用いた核膜動態の遺伝学的解析

  青木敬太; 志波優; 高田啓; 古谷寛治; 古谷寛治; 吉川博文; 吉川博文; 仁木宏典

  日本分子生物学会年会プログラム・要旨集(Web), 2011

  
• A data-driven approach to a new frontier in chromatin biology

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本環境変異原ゲノム学会大会プログラム・要旨集, 2021

  
• 融合研究への挑戦:動的細胞老化を司るヒストン蛋白質の新知見

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本生化学会大会(Web), 2021

  
• Fluctuation of protein complex against various genome stresses

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本分子生物学会年会プログラム・要旨集(Web), 2021

  
• 細胞の生き残り戦略:ゲノムストレス応答蛋白質間相互作用の揺らぎ

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本生化学会大会(Web), 2019

  
• ゲノムストレス応答における機能的タンパク質複合体のゆらぎに着目した生化学研究の新たな展望

  井倉毅; 古谷寛治; 白木琢磨; 井倉正枝

  日本生化学会大会(Web), 2018

  
• ゲノムストレス応答における機能的蛋白質複合体フラクチュエーション

  井倉毅; 白木琢磨; 古谷寛治; 井倉正枝

  日本生化学会大会(Web), 2017

  
• ゲノムストレス応答における普遍性と多様性の相互転換 DNA損傷応答における動的クロマチン平衡とその意義

  井倉 毅; 古谷 寛治; 松田 俊; 松田 知成; 松田 涼; 田代 聡; 井倉 正枝

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015, Invited

  
• LC/MS/MSを用いたDNA修復・損傷応答タンパク質及びヒストン修飾の絶対定量

  松田俊; 井倉正枝; 古谷寛治; 井倉毅; 松田知成

  日本環境変異原学会大会プログラム・要旨集, 24 Nov. 2015

  
• Diversity and dynamics analysis of phosphorylation and acetylation of histone H2AX by absolute quantification

  松田俊; 古谷寛治; 井倉正枝; 井倉毅; 松田知成

  日本プロテオーム学会大会プログラム・抄録集, 2015

  

Presentations

• ゲノムストレス下におけるがん異常増殖の仕組みの分子理解への取り組み

  Kanji FURUYA; Masae IKURA; Tsuyoshi IKURA

  The Japanese Radiation Research Society annual meeting, 15 Sep. 2022, Invited

  
• Phosphorylation-dependent signaling under genome damage stress is modulated by autophagy system

  Kanji FURUYA; Masae IKURA; Tsuyoshi IKURA

  The 43rd Annual Meeting of Molecular Biology Society of Japan, 03 Dec. 2020, Invited

  
• A new role of autophagy in cancer proliferation signaling revealed by cancer database analysis

  Kanji FURUYA; Masae IKURA; Tsuyoshi IKURA

  The 42nd Annual Meeting of Molecular Biology Society of Japan, 03 Dec. 2019

  
• Interplay between autophagy regulation and cancer signaling

  Kanji FURUYA; Masae IKURA; Tsuyoshi IKURA

  The 62nd Annual Meeting of Japanese Radiation Research Society, 15 Nov. 2019

  
• オートファジー機構からみたがん細胞のゲノムDNA損傷ストレス耐性獲得戦略

  古谷寛治

  第91回日本生化学会大会, 26 Sep. 2018, Invited

  
• ゲノムDNA損傷応答機構の制御とがんシグナリング

  古谷寛治

  第６回バイオシグナル研究会（神戸大学）, 16 Mar. 2018, Invited

  
• ゲノム損傷ストレス下での細胞増殖を保障する CDK-PLK1 経路による DNA 損傷シグナリングの調節

  古谷寛治

  第35回 染色体ワークショップ・第16回 核ダイナミクス研究会 合同開催, 20 Dec. 2017

  
• CDK-PLK1 axis targets DNA checkpoint sensor protein RAD9, promoting tolerance to genotoxic stress and cell proliferation

  Kanji Furuya

  33rd International Symposium of Radiation Biology Center, 04 Dec. 2017, Invited

  
• ゲノム損傷ストレス下での細胞増殖を保障するCDK-PLK1経路によるDNA損傷シグナリングの調節

  古谷寛治

  日本放射線影響学会第60回大会, 25 Oct. 2017, Invited

  
• DNAチェックポイント因子Rad9の機能制御を担うCdk-Plk1依存的経路の意義

  古谷寛治

  第39回 日本分子生物学会年会, 30 Nov. 2016

  
• DNA損傷に対する細胞周期進行の頑強性を付与するDNA損傷チェックポイントダイナミクス

  古谷寛治

  第89回日本生化学会大会、シンポジウム「細胞のロバストネスを規定するタンパク質複合体のダイナミクス」, 25 Sep. 2016, Invited

  
• DNA損傷応答の開始と収束

  古谷寛治

  千葉大学理学研究科セミナー, 25 Dec. 2014, Invited

  
• Cdk-Plk axis to destabilize a checkpoint protein Rad9

  Kanji Furuya

  The 4D nucleome 2014, 17 Dec. 2014

  
• Cdk-Plk axis to destabilize a checkpoint protein Rad9

  Kanji Furuya

  The 9th 3R symposium, 17 Nov. 2014

  
• Phosphorylation on checkpoint protein Rad9 contribute to genomic stability

  Kanji Furuya

  日本放射線影響学会 第57回大会, 01 Oct. 2014

  
• DNA修復・複製の連携役としてのチェックポイント機構とクロマチン制御の機能関連

  古谷寛治

  新学術領域 ゲノム普遍的制御 第５回領域班会議, 07 May 2014

  
• チェックポイントタンパク質Rad9のリン酸化による動態制御

  古谷寛治

  第22回 DNA複製・組換え・修復ワークショップ, 04 Feb. 2014

  
• The regulation of chromatin binding of Rad9 via its phosphorylation

  Kanji Furuya

  International Conference, Kyoto, 2014, “Replication, repair and transcription; coupling mechanisms and chromatin dynamics for genome integrity”, 04 Feb. 2014

  
• Phosphorylation on Rad9 checkpoint clamp protein contributes to genomic stability

  Kanji Furuya

  第36回日本分子生物学会年会、ワークショップ, 03 Dec. 2013

  
• チェックポイントタンパク質Rad9のリン酸化による動態制御

  古谷寛治

  日本放射線影響学会第56回大会, 18 Oct. 2013

  
• チェックポイントタンパク質のダイナミクス制御

  古谷寛治

  遺伝研研究集会「染色体DNAの安定維持の分子メカニズム」, 27 Sep. 2013

  
• DNA修復・複製の連携役としてのチェックポイント機構とクロマチン制御の機能関連

  古谷寛治

  新学術領域 ゲノム普遍的制御 第4回領域班会議, 08 May 2013

  
• チェックポイントタンパク質のダイナミクス制御

  古谷寛治

  日本分子生物学会年会、ワークショップ, 13 Dec. 2012

  
• The regulation of checkpoint proteins by checkpoint kinase ATR and DNA replication kinase DDK

  古谷寛治

  分子生物学会年会, 16 Dec. 2011

  
• DDK phosphorylates checkpoint clamp Rad9 and promotes its release from damaged Chromatin.

  古谷寛治

  分子生物学会年会, 08 Dec. 2010

  
• DDK phosphorylates checkpoint clamp Rad9 and promotes its release from damaged Chromatin

  古谷寛治

  国際3R シンポジウム, 26 Oct. 2010

  

Books and Other Publications

• 身心変容技法シリーズ③身心変容と医療／表現～近代と伝統 先端科学と古代シャーマニズムを結ぶ身体と心の全体性

  鎌田東二 他, Joint work, 分子生物学的視点からみた外的ストレスと恒常性維持

  日本能率協会マネジメントセンター, Mar. 2021

  
• 身心変容技法 研究年報 第8号

  鎌田東二 他, Joint work, 身心変容的分子生物学のススメ

  Mar. 2019

  
• 京大発!フロンティア生命科学

  京都大学大学院生命科学研究科, Joint work, 遺伝情報の担い手ーDNA

  講談社, Mar. 2018, Not refereed

  
• 遺伝子図鑑

  国立遺伝学研究所; 遺伝子図鑑; 編集委員会, Contributor, 酵母

  悠書館, 2013, Not refereed

  

External funds: Kakenhi

• Understanding balanced diets for animal growth through a prey-predator interspecies genetic approach

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Tadashi Uemura

  From 18 Jul. 2017, To 31 Mar. 2021, Project Closed

  栄養;成長;生物間相互作用;マルチオミクス;共生微生物叢;ショウジョウバエ;酵母;共生微生物;オミックス;共生細菌;共生真菌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17KT0018/
• Toward understanding of molecular mechanism underlies adaptive DNA checkpoint system that promotes tumorigenesis

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Furuya Kanji

  From 01 Apr. 2017, To 31 Mar. 2021, Project Closed

  オートファジー;PLK1;細胞増殖;DNA複製;DNA損傷;チェックポイント;がん;細胞周期;リン酸化;データベース;放射線;シグナル伝達

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K07284/
• Transformation and Spiritual Violence

  Grant-in-Aid for Scientific Research (A)

  Sophia University;Kyoto University

  TOJI KAMATA

  From 01 Apr. 2015, To 31 Mar. 2019, Project Closed

  身心変容技法;霊的暴力;瞑想;脳神経科学;マインドフルネス;神秘体験;オウム真理教事件;悪;ワザ;負の感情処理;霊的虐待;身体;負の感情;修行;負の感情の浄化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H01866/
• DNA修復・複製の連携役としてのチェックポイント機構とクロマチン制御の機能関連

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  古谷 寛治

  From 01 Apr. 2013, To 31 Mar. 2015, Project Closed

  チェックポイント;GFP;DNA損傷;リン酸化;ダイナミクス;分子生物

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-25131707/
• The investigation of the feedback regulation for interplay between DNA damage detection and repair

  Grant-in-Aid for Young Scientists (A)

  Kyoto University

  Kanji FURUYA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  DNA損傷;チェックポイント;DNA修復;放射線;リン酸化;ダイナミクス;タンパク質分解;ATP分解酵素;分子生物;キナーゼ;Rad9

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24687023/
• The construction of a module to visualize DNA damage signaling in live cells

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Kanji FURUYA

  From 01 Apr. 2012, To 31 Mar. 2014, Project Closed

  蛍光タンパク質;チェックポイント;細胞周期;ライブイメージング;分子生物学;リン酸化;DNA損傷

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24651046/
• ＤＮＡ修復・複製の連携役としてのチェックポイント機構とクロマチン制御の機能関連

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  古谷 寛治

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  チェックポイント;FRAP;Rad9;DNA損傷;DNA修復;クロマチン

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-23131515/
• Toward the understanding of the switching mechanism between DNA checkpo i nt and repa i r mach i neries at DNA damage s i tes.

  Grant-in-Aid for Young Scientists (B)

  Kyoto University;National Institute of Genetics

  Kanji FURUYA

  From 01 Apr. 2010, To 31 Mar. 2012, Project Closed

  DNA損傷;DNA修復;細胞周期細胞周期;チェックポイント;リン酸化;Rad9;DDK

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22770178/
• A construction of real-time detection probe for intracellular DNA checkpoint activation

  Grant-in-Aid for Young Scientists (Start-up)

  National Institute of Genetics

  Kanji FURUYA

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  バイオイメージング;細胞内情報伝達;細胞周期;環境応答

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19870029/
• Molecular mechanism of microbial DNA partitioning : structure and function

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  National Institute of Genetics

  Hironori NIKI

  From 01 Apr. 2005, To 31 Mar. 2010, Project Closed

  染色体;分配;DNA結合;無核;細胞分裂;バクテリア;セントロメア;SopAタンパク質;MreBタンパク質;無核細胞;核様体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17080009/
• Understanding the mechanism underlies autophagy and PLK1 cooperating tumorigenic pathway

  Grant-in-Aid for Scientific Research (C)

  Basic Section 63020:Radiation influence-related

  Kyoto University

  古谷 寛治

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  オートファジー;リン酸化;放射線発がん;データベース

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K12370/

External funds: others

• 放射線適応応答とDNA 損傷チェックポイント制御との機能関連

  上原記念生命科学財団

  From 2011, To 2012

  古谷寛治
• DNA 損傷部位上におけるチェックポイントタンパ ク質ネットワークのプロテオミクス解析

  武田科学振興財団

  From 2011, To 2012

  古谷寛治
• アミノ酸代謝とがん

  公益財団法人健康科学財団

  From 01 May 2018, To 30 Apr. 2019

  古谷寛治

Education

Teaching subject(s)

• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Practice in Biology I

  N420, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Practice in Biology I

  N420, Spring, Institute for Liberal Arts and Sciences, 2
• From Apr. 2012, To Mar. 2013

  Life and Radiation

  Spring, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Life and Radiation

  Spring, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Life and Radiation

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Life and Radiation

  Spring, 全学共通科目
• From Apr. 2016, To Mar. 2017

  Advanced Course in Chromosome Researches

  Fall, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Course in Chromosome Researches

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Course in Chromosome Researches

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2019, To Mar. 2020

  Advanced Course in Chromosome Researches

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Course in Chromosome Researches

  Spring, 生命科学研究科

Administration

School management (title, position)

• From 01 Apr. 2023, To 31 Mar. 2025

  京都大学放射線障害予防小委員会　委員
• From 01 Apr. 2020, To 31 Mar. 2023

  京都大学放射線障害予防小委員会　委員

Faculty management (title, position)

• From 01 Apr. 2023, To 31 Mar. 2025

  医学部構内実験排水系管理委員会
• From 01 Apr. 2018, To 31 Mar. 2024

  医学部・病院構内交通委員会
• From 01 May 2018, To 31 Mar. 2023

  情報発信・ホームページ委員会委員
• From 01 Aug. 2019

  放射線障害防止委員会５号（放生研）委員（放射線管理責任者）
• From 01 Apr. 2020, To 31 Mar. 2023

  衛生管理補助者
• From 01 Apr. 2020, To 31 Mar. 2022

  放射線管理責任者