Basic Information

Faculty

• Faculty of Engineering

Concurrent Affiliation

• Institute for Advanced Study, 物質－細胞統合システム拠点, 連携主任研究者

Professional Memberships

• 日本薬理学会
• 日本生化学会
• 北米神経科学学会
• 日本生理学会

Academic Degree

• 工学修士(京都大学)
• 博士（医学）(京都大学)

Research History

• From 2004, To 2009

  京都大学 工学(系)研究科(研究院), 教授
• From 2003, To 2008

  京都大学 工学研究科, 教授
• From 2007

  京都大学 大学院・工学研究科, 教授
• From 2005, To 2006

  Kyoto University, Graduate School of Engineering, 教授
• From 2003, To 2005

  京都大学 大学院・工学研究科, 教授
• From 2002, To 2003

  岡崎国立共同研究機構, 教授
• From 2001, To 2002

  岡崎国立共同研究機構 統合バイオサイエンスセンター, 教授
• From 1998, To 2001

  岡崎国立共同研究機構・生理学研究所, 助教授
• From 2001

  岡崎国立共同研究機構 総合バイオサイエンスセンター, 教授
• From 1996, To 2000

  岡崎国立共同研究機構, 助教授
• From 1996

  岡崎国立共同研究機構, 教授
• From 1992, To 1993

  Kyoto University, 助手・医学部

Language of Instruction

• English

ID,URL

• J-Global ID

  201101022156605492

• External link

  http://kaken.nii.ac.jp/ja/r/80212265

Website(s) (URL(s))

• http://www.ges.kyoto-u.ac.jp/cyp/modules/contents/index.php/shokai/faculty_staff/e_systemsbio.html
• http://www.sbchem.kyoto-u.ac.jp/mori-lab/

researchmap URL

• https://researchmap.jp/ymori

Research

Research Topics, Overview of the research

• Research Topics

  Origin of my research comes from organic synthetic chemistry. I went in to the field of biochemistry and molecular biology, and have studied mainly on ion channels, which mediate Ca2+ influx, through molecular/functional identification and elucidation of biological significance of Ca2+ infulx channels. Now, I focus on presynaptic active zones, which provide Ca2+ channels with molecular niche, where they exert physiological roles, and as well on TRP channels, which sense and integrate redox status of cells. I enjoy researches by taking a comprehensive approach to ion channels, ranging from basic science including evolutionary biology to application science such as elucidation of channelpathies and invention of ion channel-based drugs and nano-devivices.

Research Interests

• 包括脳ネットワーク
• バイオテクノロジー
• 生体分子医学
• 受容体活性化Ca2+チャネル
• 化学遊走
• G蛋白質
• 活性酸素
• カルシウムシグナル
• 受容体活性化Ca^<2+>チャネル
• ノックアウトマウス
• 光アフィニティーラベル化
• 神経疾患モデル
• 分子複合体
• 生体分子
• 生理学
• 薬理学
• 不活性化
• イオンチャネル
• シグナル伝達
• 細胞・組織
• 小胞体
• 炎症
• ミュータントマウス
• 遺伝子
• 運動失調
• カルシウムチャンネル
• バイオセンサー
• Ca^<2+>チャネル
• カルシウム
• カルシウムチャネル
• チャネル

Research Areas

• Life sciences, Clinical pharmacy
• Life sciences, Physiology
• Life sciences, Neuroscience - general
• Life sciences, Functional biochemistry
• Life sciences, Medical biochemistry

Papers

• The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production

  Masashi Kakae; Hiroki Nakajima; Shota Tobori; Ayaka Kawashita; Jun Miyanohara; Misa Morishima; Kazuki Nagayasu; Takayuki Nakagawa; Eiji Shigetomi; Schuichi Koizumi; Yasuo Mori; Shuji Kaneko; Hisashi Shirakawa

  Science Advances, Jul. 2023, Peer-reviewed

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• Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post-ischaemic blood flow recovery

  T Numaga-Tomita; T Shimauchi; Y Kato; K Nishiyama; A Nishimura; K Sakata; H Inada; S Kita; T Iwamoto; J Nabekura; L Birnbaumer; Y Mori; M Nishida

  BRITISH JOURNAL OF PHARMACOLOGY, Jan. 2023, Peer-reviewed

  
• Vital but vulnerable: Human TRPV6 is a trade-off of powerful Ca2+ uptake and susceptibility to epithelial barrier dysfunction Comment

  Y Mori; M Omori; A Nakao

  CELL CALCIUM, Nov. 2022, Peer-reviewed

  
• N-Methylamide-structured SB366791 derivatives with high TRPV1 antagonistic activity: toward PET radiotracers to visualize TRPV1

  T Kida; N Takahashi; MX Mori; JCH Sun; H Oota; K Nishino; T Okauchi; Y Ochi; D Kano; U Tateishi; Y Watanabe; YL Cui; Y Mori; H Doi

  RSC MEDICINAL CHEMISTRY, Oct. 2022, Peer-reviewed

  
• Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through beta-adrenoceptors

  S Oda; K Nishiyama; Y Furumoto; Y Yamaguchi; A Nishimura; XK Tang; Y Kato; T Numaga-Tomita; T Kaneko; S Mangmool; T Kuroda; R Okubo; M Sanbo; M Hirabayashi; Y Sato; Y Nakagawa; K Kuwahara; R Nagata; G Iribe; Y Mori; M Nishida

  NATURE COMMUNICATIONS, Oct. 2022, Peer-reviewed

  
• The mechanosensitive ion channel PIEZO1 promotes satellite cell function in muscle regeneration

  K Hirano; M Tsuchiya; A Shiomi; S Takabayashi; M Suzuki; Y Ishikawa; Y Kawano; Y Takabayashi; K Nishikawa; K Nagao; E Umemoto; Y Kitajima; Y Ono; K Nonomura; H Shintaku; Y Mori; M Umeda; Y Hara

  LIFE SCIENCE ALLIANCE, Feb. 2022, Peer-reviewed

  
• Critical contributions of pre-S1 shoulder and distal TRP box in DAG-activated TRPC6 channel by PIP2 regulation

  Masayuki X. Mori; Ryo Okada; Reiko Sakaguchi; Hideharu Hase; Yuko Imai; Onur K. Polat; Satoru G. Itoh; Hisashi Okumura; Yasuo Mori; Yasushi Okamura; Ryuji Inoue

  SCIENTIFIC REPORTS, Jun. 2022, Peer-reviewed

  
• A two-step screening to optimize the signal response of an auto-fluorescent protein-based biosensor

  Shunsuke Tajima; Eiji Nakata; Reiko Sakaguchi; Masayuki Saimura; Yasuo Mori; Takashi Morii

  RSC ADVANCES, May 2022, Peer-reviewed

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• C-type natriuretic peptide facilitates autonomic Ca²⁺ entry in growth plate chondrocytes for stimulating bone growth

  Yuu Miyazaki; Atsuhiko Ichimura; Ryo Kitayama; Naoki Okamoto; Tomoki Yasue; Feng Liu; Takaaki Kawabe; Hiroki Nagatomo; Yohei Ueda; Ichiro Yamauchi; Takuro Hakata; Kazumasa Nakao; Sho Kakizawa; Miyuki Nishi; Yasuo Mori; Haruhiko Akiyama; Kazuwa Nakao; Hiroshi Takeshima

  eLife, 2022, Peer-reviewed

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• Activation of Astrocytes in the Persistence of Post-hypoxic Respiratory Augmentation

  Isato Fukushi; Kotaro Takeda; Mieczyslaw Pokorski; Yosuke Kono; Masashi Yoshizawa; Yohei Hasebe; Akito Nakao; Yasuo Mori; Hiroshi Onimaru; Yasumasa Okada

  FRONTIERS IN PHYSIOLOGY, Oct. 2021, Peer-reviewed

  
• MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations

  Shota Tobori; Haruka Hiyama; Takahito Miyake; Yuichi Yano; Kazuki Nagayasu; Hisashi Shirakawa; Takayuki Nakagawa; Yasuo Mori; Shuji Kaneko

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2021, Peer-reviewed

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• TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel

  Tomohiro Numata; Kaori Sato-Numata; Meredith C. Hermosura; Yasuo Mori; Yasunobu Okada

  COMMUNICATIONS BIOLOGY, May 2021, Peer-reviewed

  
• Striatal TRPV1 activation by acetaminophen ameliorates dopamine D-2 receptor antagonist-induced orofacial dyskinesia

  Koki Nagaoka; Takuya Nagashima; Nozomi Asaoka; Hiroki Yamamoto; Chihiro Toda; Gen Kayanuma; Soni Siswanto; Yasuhiro Funahashi; Keisuke Kuroda; Kozo Kaibuchi; Yasuo Mori; Kazuki Nagayasu; Hisashi Shirakawa; Shuji Kaneko

  JCI INSIGHT, May 2021, Peer-reviewed

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• Possible involvement of TRPM2 activation in 5-fluorouracil-induced myelosuppression in mice

  Masaaki Ishibashi; Masakazu Ishii; Shinichiro Yamamoto; Yasuo Mori; Shunichi Shimizu

  EUROPEAN JOURNAL OF PHARMACOLOGY, Jan. 2021, Peer-reviewed

  
• Deficiency of the RI beta subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats

  Hieu Hoang Trung; Toru Yoshihara; Akito Nakao; Katsumi Hayashida; Yoshiki Hirata; Koumei Shirasuna; Mitsuru Kuwamura; Yuki Nakagawa; Takehito Kaneko; Yasuo Mori; Masahide Asano; Takashi Kuramoto

  SCIENTIFIC REPORTS, Jan. 2021, Peer-reviewed

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• A Rapid Shift from Chronic Hyperoxia to Normoxia Induces Systemic Anaphylaxis via Transient Receptor Potential Ankyrin 1 Channels on Mast Cells

  Kenshiro Matsuda; Peter D. Arkwright; Yasuo Mori; Masa-Aki Oikawa; Ryo Muko; Akane Tanaka; Hiroshi Matsuda

  JOURNAL OF IMMUNOLOGY, Dec. 2020, Peer-reviewed

  
• Transient Receptor Potential Ankyrin 1 Mediates Hypoxic Responses in Mice

  Sichong Chen; Nobuaki Takahashi; Changping Chen; Jordan L. Pauli; Chiharu Kuroki; Jun Kaminosono; Hideki Kashiwadani; Yuichi Kanmura; Yasuo Mori; Shaowu Ou; Liying Hao; Tomoyuki Kuwaki

  FRONTIERS IN PHYSIOLOGY, Oct. 2020, Peer-reviewed

  
• O-2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses

  Makoto Uchiyama; Akito Nakao; Yuki Kurita; Isato Fukushi; Kotaro Takeda; Tomohiro Numata; Ha Nam Tran; Seishiro Sawamura; Maximilian Ebert; Tatsuki Kurokawa; Reiko Sakaguchi; Alexander J. Stokes; Nobuaki Takahashi; Yasumasa Okada; Yasuo Mori

  CURRENT BIOLOGY, Sep. 2020, Peer-reviewed

  
• Ryanodine receptor mutations (G4946E and 14790K) differentially responsible for diamide insecticide resistance in diamondback moth, Plutella xylostella L.

  Akiya Jouraku; Seigo Kuwazaki; Kazuhisa Miyamoto; Makoto Uchiyama; Tatsuki Kurokawa; Emiko Mori; Masayuki X. Mori; Yasuo Mori; Shoji Sonoda

  INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, Mar. 2020, Peer-reviewed

  
• Detection of Inositol Phosphates by Split PH Domains

  Reiko Sakaguchi; Shunsuke Tajima; Yasuo Mori; Takashi Morii

  INOSITOL PHOSPHATES: METHODS AND PROTOCOLS, 2020, Peer-reviewed

  
• Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes

  Onur K. Polat; Masatoshi Uno; Terukazu Maruyama; Ha Nam Tran; Kayo Imamura; Chee Fah Wong; Reiko Sakaguchi; Mariko Ariyoshi; Kyohei Itsuki; Jun Ichikawa; Takashi Morii; Masahiro Shirakawa; Ryuji Inoue; Katsuhiko Asanuma; Jochen Reiser; Hidehito Tochio; Yasuo Mori; Masayuki X. Mori

  JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Sep. 2019, Peer-reviewed

  
• TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN

  Takuro Numaga-Tomita; Tsukasa Shimauchi; Sayaka Oda; Tomohiro Tanaka; Kazuhiro Nishiyama; Akiyuki Nishimura; Lutz Birnbaumer; Yasuo Mori; Motohiro Nishida

  FASEB JOURNAL, Sep. 2019, Peer-reviewed

  
• Hippocampus-related cognitive disorders develop in the absence of epilepsy and ataxia in the heterozygous Cacna1a mutant mice tottering

  Akito Nakao; Katsumi Hayashida; Hiroo Ogura; Yasuo Mori; Keiji Imoto

  Channels, 2022, Peer-reviewed

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• Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury

  Pengyu Zong; Jianlin Feng; Zhichao Yue; Yunfeng Li; Gongxiong Wu; Baonan Sun; Yanlin He; Barbara Miller; Albert S. Yu; Zhongping Su; Jia Xie; Yasuo Mori; Bing Hao; Lixia Yue

  NEURON, Jun. 2022, Peer-reviewed

  
• Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains

  Akira Murakami; Kohjiro Nagao; Reiko Sakaguchi; Keisuke Kida; Yuji Hara; Yasuo Mori; Kohki Okabe; Yoshie Harada; Masato Umeda

  CELL REPORTS, Mar. 2022, Peer-reviewed

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• Functionally deficient TRPV6 variants contribute to hereditary and familial chronic pancreatitis

  Shin Hamada; Emmanuelle Masson; Jian-Min Chen; Reiko Sakaguchi; Vinciane Rebours; Louis Buscail; Ryotaro Matsumoto; Yu Tanaka; Kazuhiro Kikuta; Fumiya Kataoka; Akira Sasaki; Marc Le Rhun; Hela Audin; Alain Lachaux; Bernard Caumont; Diane Lorenzo; Kareen Billiemaz; Raphael Besnard; Stephane Koch; Thierry Lamireau; Xavier De Koninck; Emmanuelle Genin; David N. Cooper; Yasuo Mori; Atsushi Masamune; Claude Ferec

  HUMAN MUTATION, Feb. 2022, Peer-reviewed

  
• Osteoclasts adapt to physioxia perturbation through DNA demethylation

  Keizo Nishikawa; Shigeto Seno; Toshitada Yoshihara; Ayako Narazaki; Yuki Sugiura; Reito Shimizu; Junichi Kikuta; Reiko Sakaguchi; Norio Suzuki; Norihiko Takeda; Hiroaki Semba; Masamichi Yamamoto; Daisuke Okuzaki; Daisuke Motooka; Yasuhiro Kobayashi; Makoto Suematsu; Haruhiko Koseki; Hideo Matsuda; Masayuki Yamamoto; Seiji Tobita; Yasuo Mori; Masaru Ishii

  EMBO REPORTS, Dec. 2021, Peer-reviewed

  
• 温覚と圧・触覚の受容体の発見 : 分子生理学の始まりの終わり

  森 泰生; 原 雄二

  化学 = Chemistry, Dec. 2021

  
• Deep-Red/Near-Infrared Turn-On Fluorescence Probes for Aldehyde Dehydrogenase 1A1 in Cancer Stem Cells

  Masahiro Oe; Koji Miki; Yoshifumi Ueda; Yasuo Mori; Aoi Okamoto; Yohei Funakoshi; Hironobu Minami; Kouichi Ohe

  ACS SENSORS, Sep. 2021, Peer-reviewed

  
• Extreme deformability of insect cell membranes is governed by phospholipid scrambling

  Akifumi Shiomi; Kohjiro Nagao; Nobuhiro Yokota; Masaki Tsuchiya; Utako Kato; Naoto Juni; Yuji Hara; Masayuki X. Mori; Yasuo Mori; Kumiko Ui-Tei; Motohide Murate; Toshihide Kobayashi; Yuri Nishino; Atsuo Miyazawa; Akihisa Yamamoto; Ryo Suzuki; Stefan Kaufmann; Motomu Tanaka; Kazuya Tatsumi; Kazuyoshi Nakabe; Hirofumi Shintaku; Semen Yesylevsky; Mikhail Bogdanov; Masato Umeda

  Cell Reports, Jun. 2021, Peer-reviewed

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• V for versatility: TRPV4 Ca2+ entry channel plays multiple roles in invadosome regulation

  Yasuo Mori

  CELL CALCIUM, Jun. 2021, Peer-reviewed

  
• Deletion of TRPC3 or TRPC6 Fails to Attenuate the Formation of Inflammation and Fibrosis in Non-alcoholic Steatohepatitis

  Kazuhiro Nishiyama; Chiemi Toyama; Yuri Kato; Tomohiro Tanaka; Akiyuki Nishimura; Ryu Nagata; Yasuo Mori; Motohiro Nishida

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Mar. 2021, Peer-reviewed

  
• 骨格筋再生過程における硬さ感知機構の役割

  原 雄二; 平野 航太郎; 森 泰生; 梅田 眞郷

  日本薬理学会年会要旨集, 2021

  
• TRPA1チャネルによるミトコンドリア活性制御

  長谷川 義晃; 浜野 智; 森 泰生; 高橋 重成

  日本薬理学会年会要旨集, 2021

  
• Role of TRPM7 channel in pancreatic cancer

  Atsuki Hosokoshi; Takahashi Nobuaki; Sakaguchi Reiko; Masamune Atsusi; Harada Hiroshi; Mori Yasuo

  Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2021

  
• TRPC5 チャネル-カベオリン-1-eNOS 複合体による血管内皮細胞におけるCa²⁺ とNOシグナルの制御

  坂口 怜子; 原 雄二; 森 誠之; 古川 哲史; 清水 俊一; 井上 隆司; 森 泰生; 髙橋 重成; 吉田 卓史; 小川 臨; 植田 誉志史; 浜野 智; 山口 佳織; 澤村 晴志朗; 山本 伸一郎

  日本薬理学会年会要旨集, 2021

  
• TNBS誘発大腸繊維化におけるマクロファージTRPM2の役割

  中本 智大; 松本 健次郎; 安田 浩之; 森 泰生; 加藤 伸一

  日本薬理学会年会要旨集, 2021

  
• TRPCチャネル選択的化合物の線維化疾患治療候補薬としての開発と核酸医薬への展開

  尼谷 明日路; 笠原 勇矢; 下條 正仁; 西田 基宏; 永田 龍; 小比賀 聡; 森 泰生

  日本薬理学会年会要旨集, 2021

  
• BARPは樹状突起スパインにおいて電位依存性カルシウムチャネルのダイナミクスを制御する

  松永 佳大; 中尾 章人; 大森 美ずき; 梶本 武利; 森 泰生

  日本薬理学会年会要旨集, 2021

  
• 酸素生物学の重要性と将来展望 (特集 HIFと疾患 : ノーベル賞受賞と将来展望)

  森 泰生

  医学のあゆみ, Jul. 2020

  
• Blockade of astrocytic activation delays the occurrence of severe hypoxia-induced seizure and respiratory arrest in mice

  Isato Fukushi; Kotaro Takeda; Makoto Uchiyama; Yuki Kurita; Mieczyslaw Pokorski; Shigefumi Yokota; Shuntaro Okazaki; Jouji Horiuchi; Yasuo Mori; Yasumasa Okada

  JOURNAL OF COMPARATIVE NEUROLOGY, Jun. 2020, Peer-reviewed

  
• Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early -Onset Chronic Pancreatitis

  Atsushi Masamune; Hiroshi Kotani; Franziska Lena Soergel; Jian-Min Chen; Shin Hamada; Reiko Sakaguchi; Emmanuelle Masson; Eriko Nakano; Yoichi Kakuta; Tetsuya Niihori; Ryo Funayama; Matsuyuki Shirota; Tatsuya Hirano; Tetsuya Kawamoto; Atsuki Hosokoshi; Kiyoshi Kume; Lara Unger; Maren Ewers; Helmut Laumen; Peter Bugert; Masayuki X. Mori; Volodymyr Tsvilovskyy; Petra Weissgerber; Ulrich Kriebs; Claudia Fecher-Trost; Marc Freichel; Kalliope N. Diakopoulos; Alexandra Berninger; Marina Lesina; Kentaro Ishii; Takao Itoi; Tsukasa Ikeura; Kazuichi Okazaki; Tom Kaune; Jonas Rosendahl; Masao Nagasaki; Yasuhito Uezono; Hana Alguel; Keiko Nakayama; Yoichi Matsubara; Yoko Aoki; Claude Ferec; Yasuo Mori; Heiko Witt; Tooru Shimosegawa

  GASTROENTEROLOGY, May 2020, Peer-reviewed

  
• Fluorescence detection of the nitric oxide-induced structural change at the putative nitric oxide sensing segment of TRPC5

  Shunsuke Tajima; Eiji Nakata; Reiko Sakaguchi; Masayuki Saimura; Yasuo Mori; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Apr. 2020, Peer-reviewed

  
• Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions

  Miki Tanaka; Kaori Hayakawa; Nozomi Ogawa; Tatsuki Kurokawa; Kenichi Kitanishi; Kenji Ite; Toshitaka Matsui; Yasuo Mori; Masaki Unno

  ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, Mar. 2020, Peer-reviewed

  
• マクロファージの機能分化を司るTRPM2チャネロソーム

  森 泰生

  上原記念生命科学財団研究報告集, 2020

  
• Transient receptor potential (TRP) channels: Biosensors for redox environmental stimuli and cellular status

  Reiko Sakaguchi; Yasuo Mori

  FREE RADICAL BIOLOGY AND MEDICINE, Jan. 2020, Peer-reviewed

  
• 細胞力覚を基軸とする骨格筋線維再生機構

  原 雄二; 平野 航太郎; 高林 征史; 竹内 真理; 土谷 正樹; 森 泰生; 梅田 眞郷

  日本薬理学会年会要旨集, 2020, Peer-reviewed

  
• Pathophysiological Role of TRPM2 in Age-Related Cognitive Impairment in Mice.

  Masashi Kakae; Jun Miyanohara; Misa Morishima; Kazuki Nagayasu; Yasuo Mori; Hisashi Shirakawa; Shuji Kaneko

  Neuroscience, 01 Jun. 2019, Peer-reviewed

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• Cnnm4 deficiency suppresses Ca2+ signaling and promotes cell proliferation in the colon epithelia

  Daisuke Yamazaki; Ayaka Hasegawa; Yosuke Funato; Nam Tran Ha; Masayuki X. Mori; Yasuo Mori; Toshiro Sato; Hiroaki Miki

  ONCOGENE, May 2019, Peer-reviewed

  
• TRPM7 channels mediate spontaneous Ca2+ fluctuations in growth plate chondrocytes that promote bone development.

  Nianchao Qian; Atsuhiko Ichimura; Daisuke Takei; Reiko Sakaguchi; Akihiro Kitani; Ryohei Nagaoka; Masato Tomizawa; Yuu Miyazaki; Hitoshi Miyachi; Tomohiro Numata; Sho Kakizawa; Miyuki Nishi; Yasuo Mori; Hiroshi Takeshima

  Science signaling, 09 Apr. 2019, Peer-reviewed

  
• Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior

  Wataru Ota; Yusuke Nakane; Makiko Kashio; Yoshiro Suzuki; Kazuhiro Nakamura; Yasuo Mori; Makoto Tominaga; Takashi Yoshimura

  SCIENTIFIC REPORTS, Mar. 2019, Peer-reviewed

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• TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility.

  Chihiro Andoh; Naoya Nishitani; Emina Hashimoto; Yuma Nagai; Keizo Takao; Tsuyoshi Miyakawa; Takayuki Nakagawa; Yasuo Mori; Kazuki Nagayasu; Hisashi Shirakawa; Shuji Kaneko

  Brain research, 01 Feb. 2019, Peer-reviewed

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• Protective Effects of Duloxetine against Cerebral Ischemia-Reperfusion Injury via Transient Receptor Potential Melastatin 2 Inhibition

  Takahiro Toda; Shinichiro Yamamoto; Noriko Umehara; Yasuo Mori; Minoru Wakamori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Feb. 2019, Peer-reviewed

  
• ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells.

  Mica Ohara-Imaizumi; Kyota Aoyagi; Hajime Yamauchi; Masashi Yoshida; Masayuki X Mori; Yamato Hida; Ha Nam Tran; Masamichi Ohkura; Manabu Abe; Yoshihiro Akimoto; Yoko Nakamichi; Chiyono Nishiwaki; Hayato Kawakami; Kazuo Hara; Kenji Sakimura; Shinya Nagamatsu; Yasuo Mori; Junichi Nakai; Masafumi Kakei; Toshihisa Ohtsuka

  Cell reports, 29 Jan. 2019, Peer-reviewed

  
• TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure

  Jaime S. Horton; Takuya Shiraishi; Naghum Alfulaij; Andrea L. Small-Howard; Helen C. Turner; Tatsuki Kurokawa; Yasuo Mori; Alexander J. Stokes

  CHANNELS, Jan. 2019, Peer-reviewed

  
• ⼼筋梗塞後のマウス心臓におけるミトコンドリアーアクチン相互作⽤の病態生理学的意義

  田中 智弘; 安田 智; 佐藤 陽治; 桑原 宏一郎; 熊谷 嘉人; 赤池 孝章; 井手 友美; 王子田 彰夫; 森 泰生; 西田 基宏; 西村 明幸; 下田 翔; 島内 司; 外山 隆; 北島 直幸; 石川 達也; 進藤 直哉; 沼賀-富田 拓郎

  日本薬理学会年会要旨集, 2019, Peer-reviewed

  
• ASTROCYTIC ACTIVATION IS NECESSARY FOR HYPOXIC RESPIRATORY FACILITATION

  Isato Fukushi; Makoto Uchiyama; Yuki Kurita; Itaru Yazawa; Shuntaro Okazaki; Yosuke Kono; Kotaro Takeda; Hiroshi Onimaru; Yasuo Mori; Yasumasa Okada

  RESPIROLOGY, Nov. 2018

  
• TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.

  Masato Tsutsui; Ryo Hirase; Sakie Miyamura; Kazuki Nagayasu; Takayuki Nakagawa; Yasuo Mori; Hisashi Shirakawa; Shuji Kaneko

  The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 Sep. 2018, Peer-reviewed

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• Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus

  Kenjiro Matsumoto; Hiroki Kawanaka; Masatoshi Hori; Kosuke Kusamori; Daichi Utsumi; Takuya Tsukahara; Kikuko Amagase; Syunji Horie; Akira Yamamoto; Hiroshi Ozaki; Yasuo Mori; Shinichi Kato

  American Journal of Physiology - Gastrointestinal and Liver Physiology, Jul. 2018, Peer-reviewed

  
• Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance

  Nobuaki Takahashi; Hsing-Yu Chen; Isaac S. Harris; Daniel G. Stover; Laura M. Selfors; Roderick T. Bronson; Thomas Deraedt; Karen Cichowski; Alana L. Welm; Yasuo Mori; Gordon B. Mills; Joan S. Brugge

  Cancer Cell, 11 Jun. 2018, Peer-reviewed

  
• TRPM2 mediates neutrophil killing of disseminated tumor cells

  Maya Gershkovitz; Yaki Caspi; Tanya Fainsod-Levi; Ben Katz; Janna Michaeli; Saleh Khawaled; Shaya Lev; Lola Polyansky; Merav E. Shaul; Ronit V. Sionov; Leonor Cohen-Daniel; Rami I. Aqeilan; Yoav D. Shaul; Yasuo Mori; Rotem Karni; Zvi G. Fridlender; Alexander M. Binshtok; Zvi Granot

  Cancer Research, 15 May 2018, Peer-reviewed

  
• Sensors and regulatory mechanisms of thermal physiology

  Yasuo Mori; Thomas Voets

  Pflugers Archiv European Journal of Physiology, 01 May 2018, Peer-reviewed

  
• Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation

  Masaki Tsuchiya; Yuji Hara; Masaki Okuda; Karin Itoh; Ryotaro Nishioka; Akifumi Shiomi; Kohjiro Nagao; Masayuki Mori; Yasuo Mori; Junichi Ikenouchi; Ryo Suzuki; Motomu Tanaka; Tomohiko Ohwada; Junken Aoki; Motoi Kanagawa; Tatsushi Toda; Yosuke Nagata; Ryoichi Matsuda; Yasunori Takayama; Makoto Tominaga; Masato Umeda

  NATURE COMMUNICATIONS, May 2018, Peer-reviewed

  
• TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion

  Jun Miyanohara; Masashi Kakae; Kazuki Nagayasu; Takayuki Nakagawa; Yasuo Mori; Ken Arai; Hisashi Shirakawa; Shuji Kaneko

  JOURNAL OF NEUROSCIENCE, Apr. 2018, Peer-reviewed

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• DNA Origami Scaffolds as Templates for Functional Tetrameric Kir3 K+ Channels.

  Tatsuki Kurokawa; Shigeki Kiyonaka; Eiji Nakata; Masayuki Endo; Shohei Koyama; Emiko Mori; Nam Ha Tran; Huyen Dinh; Yuki Suzuki; Kumi Hidaka; Masaaki Kawata; Chikara Sato; Hiroshi Sugiyama; Takashi Morii; Yasuo Mori

  Angewandte Chemie (International ed. in English), 01 Mar. 2018, Peer-reviewed

  
• In vitro and in vivo characterization of modulation of the vacuolar cation channel TRPY1 from Saccharomyces cerevisiae

  Shin Hamamoto; Yasuo Mori; Isamu Yabe; Nobuyuki Uozumi

  FEBS Journal, 01 Mar. 2018, Peer-reviewed

  
• Ca2+-Dependent Inactivation Mediated by Calmodulin in TRPC6 Channel Underlies FSGS Channelopathy

  Masatoshi Uno; Onur K. Polat; Ha Nam Tran; Shota Yamaji; Yasuo Mori; Hidehito Tochio; Masayuki X. Mori

  BIOPHYSICAL JOURNAL, Feb. 2018

  
• Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders

  Hideo Hagihara; Vibeke S Catts; Yuta Katayama; Hirotaka Shoji; Tsuyoshi Takagi; Freesia L Huang; Akito Nakao; Yasuo Mori; Kuo-Ping Huang; Shunsuke Ishii; Isabella A Graef; Keiichi I Nakayama; Cynthia Shannon Weickert; Tsuyoshi Miyakawa

  Neuropsychopharmacology, 01 Feb. 2018, Peer-reviewed

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• Functional Charaterization of Zebrafish Transient Receptor Potential Melastatin 2

  Ha Nam Tran; Jure Hederih; Tomohiro Numata; Masayuki X. Mori; Shingo Maegawa; Hiroshi Hosokawa; Yasuo Mori

  BIOPHYSICAL JOURNAL, Feb. 2018

  
• TRP Channels in the Brain What Are They There For?

  Seishiro Sawamura; Hisashi Shirakawa; Takayuki Nakagawa; Yasuo Mori; Shuji Kaneko

  NEUROBIOLOGY OF TRP CHANNELS, 2018

  
• Down-regulation of the Wnt/beta-catenin signaling pathway by Cacnb4

  Mohamad Rima; Marwa Daghsni; Anais Lopez; Ziad Fajloun; Lydie Lefrancois; Mireia Dunach; Yasuo Mori; Philippe Merle; Juan L. Bruses; Michel De Waard; Michel Ronjat

  MOLECULAR BIOLOGY OF THE CELL, Dec. 2017, Peer-reviewed

  
• Mast cell hyperactivity underpins the development of oxygen-induced retinopathy

  Kenshiro Matsuda; Noriko Okamoto; Masatoshi Kondo; Peter D. Arkwright; Kaoru Karasawa; Saori Ishizaka; Shinichi Yokota; Akira Matsuda; Kyungsook Jung; Kumiko Oida; Yosuke Amagai; Hyosun Jang; Eiichiro Noda; Ryota Kakinuma; Koujirou Yasui; Uiko Kaku; Yasuo Mori; Nobuyuki Onai; Toshiaki Ohteki; Akane Tanaka; Hiroshi Matsuda

  JOURNAL OF CLINICAL INVESTIGATION, Nov. 2017, Peer-reviewed

  
• Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin

  Takahito Miyake; Saki Nakamura; Zhao Meng; Satoshi Hamano; Keisuke Inoue; Tomohiro Numata; Nobuaki Takahashi; Kazuki Nagayasu; Hisashi Shirakawa; Yasuo Mori; Takayuki Nakagawa; Shuji Kaneko

  FRONTIERS IN PHYSIOLOGY, Nov. 2017, Peer-reviewed

  
• Transient receptor potential melastatin 2 channels (TRPM2) mediate neonatal hypoxic-ischemic brain injury in mice

  Sammen Huang; Ekaterina Turlova; Feiya Li; Mei-hua Bao; Vivian Szeto; Raymond Wong; Ahmed Abussaud; Haitao Wang; Shuzhen Zhu; Xinzheng Gao; Yasuo Mori; Zhong-Ping Feng; Hong-Shuo Sun

  EXPERIMENTAL NEUROLOGY, Oct. 2017, Peer-reviewed

  
• Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing

  Tomohiro Numata; Kunichika Tsumoto; Kazunori Yamada; Tatsuki Kurokawa; Shinichi Hirose; Hideki Nomura; Mitsuhiro Kawano; Yoshihisa Kurachi; Ryuji Inoue; Yasuo Mori

  SCIENTIFIC REPORTS, Aug. 2017, Peer-reviewed

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• Strategy to Attain Remarkably High Photoinduced Charge-Separation Yield of Donor-Acceptor Linked Molecules in Biological Environment via Modulating Their Cationic Moieties

  Ning Cai; Yuta Takano; Tomohiro Numata; Ryuji Inoue; Yasuo Mori; Tatsuya Murakami; Hiroshi Imahori

  JOURNAL OF PHYSICAL CHEMISTRY C, Aug. 2017, Peer-reviewed

  
• TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy

  Tsukasa Shimauchi; Takuro Numaga-Tomita; Tomoya Ito; Akiyuki Nishimura; Ryosuke Matsukane; Sayaka Oda; Sumio Hoka; Tomomi Ide; Norimichi Koitabashi; Koji Uchida; Hideki Sumimoto; Yasuo Mori; Motohiro Nishida

  JCI INSIGHT, Aug. 2017, Peer-reviewed

  
• The beta(4) subunit of the voltage-gated calcium channel (Cacnb4) regulates the rate of cell proliferation in Chinese Hamster Ovary cells

  Mohamad Rima; Marwa Daghsni; Stephan De Waard; Nathalie Gaborit; Ziad Fajloun; Michel Ronjat; Yasuo Mori; Juan L. Bruses; Michel De Waard

  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, Aug. 2017, Peer-reviewed

  
• TRP channels in oxygen physiology: distinctive functional properties and roles of TRPA1 in O-2 sensing

  Yasuo Mori; Nobuaki Takahashi; Tatsuki Kurokawa; Shigeki Kiyonaka

  PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES, Jul. 2017, Peer-reviewed

  
• Genetic knock-out of transient receptor potential melastatin 2 (TRPM2) channels is neuroprotective against hypoxic-ischemic brain injury in the neonatal mouse

  Ekaterina Turlova; Sammen Huang; Fei-ya Li; Mei-hua Bao; Vivian Szeto; Raymond Wong; Ahmed Abussaud; Hai-tao Wang; Shu-zhen Zhu; Xin-zheng Gao; Yasuo Mori; Zhong-ping Feng; Hong-shuo Sun

  ACTA PHARMACOLOGICA SINICA, Jul. 2017, Peer-reviewed

  
• C-terminal splice variants of P/Q-type Ca2+ channel Ca(V)2.1 alpha(1) subunits are differentially regulated by Rab3-interacting molecule proteins

  Mitsuru Hirano; Yoshinori Takada; Chee Fah Wong; Kazuma Yamaguchi; Hiroshi Kotani; Tatsuki Kurokawa; Masayuki X. Mori; Terrance P. Snutch; Michel Ronjat; Michel De Waard; Yasuo Mori

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 2017, Peer-reviewed

  
• Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway

  Xibao Liu; Baijuan Gong; Lorena Brito de Souza; Hwei Ling Ong; Krishna P. Subedi; Kwong Tai Cheng; William Swaim; Changyu Zheng; Yasuo Mori; Indu S. Ambudkar

  SCIENCE SIGNALING, Jun. 2017, Peer-reviewed

  
• Molecular characterization of mutations in RyR of Plutella xylostella resistant to diamide insecticides

  Makoto Uchiyama; Tatsuki Kurokawa; Tasuku Kimura; Emiko Mori; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• Multi-point interaction between P/Q-type voltage-dependent Ca2+ channel and alpha-RIMs augments RIMs suppressive effect on voltage dependent inactivation

  Mitsuru Hirano; Kazuma Yamaguchi; Yoshinori Takada; Takeshi Kotani; Tatsuki Kurokawa; Masayuki. X. Mori; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• Protective effect of duloxetine on cerebral ischemia-reperfusion injury by TRPM2 inhibition

  Takahir Toda; Shinichiro Yamamoto; Takaharu Negoro; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• Oxygen-sensitive TRPA1 channel controls the function of mitochondria

  Takuya Shiraishi; Satoshi Hamano; Nobuaki Takahashi; Maximillian Ebert; Reiko Sakaguchi; Tatsuki Kurokawa; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• The regulatory effect of oxaliplatin on human TRPA1 cold sensitivity

  Takahito Miyake; Saki Nakamura; Meng Zhao; Kanako So; Keisuke Inoue; Tomohiro Numata; Nobuaki Takahashi; Hisashi Shirakawa; Yasuo Mori; Takayuki Nakagawa; Shuji Kaneko

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017, Peer-reviewed

  
• Visualization of organelle-specific thermodynamics

  Yuta Yasuyoshi; Masahiko Hatano; Reiko Sakaguchi; Shigeki Kiyonaka; Itaru Hamachi; Takashi Morii; Takenao Yoshizaki; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• FUNCTIONAL CHARATERIZATION OF ZEBRAFISH TRANSIENT RECEPTOR POTENTIAL MELASTATIN 2 IN HEK 293 CELL LINE

  Ha Nam Tran; Tomohiro Numata; Masayuki X. Mori; Shingo Maegawa; Hiroshi Hosokawa; Shingo Tanaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• Development of a fluorescent probe to visualize and isolate hydrogen peroxide-exposed tumor cells in tumor microenvironment

  Yoshifumi Ueda; Keisuke Inoue; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2017

  
• 薬学における酸素生理学のすゝめ

  森 泰生

  ファルマシア, Jan. 2017

  
• Validation of intracellular thermal changes by fluorescent thermosensors

  清中 茂樹; 坂口 怜子; 森 泰生; 吉崎 武尚

  生体の科学, Jan. 2016

  
• Optical control of neuronal firing via photoinduced electron transfer in donor-acceptor conjugates

  Yuta Takano; Tomohiro Numata; Kazuto Fujishima; Kazuaki Miyake; Kazuya Nakao; Wesley David Grove; Ryuji Inoue; Mineko Kengaku; Shigeyoshi Sakaki; Yasuo Mori; Tatsuya Murakami; Hiroshi Imahori

  CHEMICAL SCIENCE, 2016, Peer-reviewed

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• Validating subcellular thermal changes revealed by fluorescent thermosensors

  Shigeki Kiyonaka; Reiko Sakaguchi; Itaru Hamachi; Takashi Morii; Takenao Yoshizaki; Yasuo Mori

  NATURE METHODS, Sep. 2015, Peer-reviewed

  
• Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles

  Hirotaka Nakatsuji; Tomohiro Numata; Nobuhiro Morone; Shuji Kaneko; Yasuo Mori; Hiroshi Imahori; Tatsuya Murakami

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Sep. 2015, Peer-reviewed

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• Transient receptor potential channel M2 contributes to neointimal hyperplasia in vascular walls

  Xiaochen Ru; Changbo Zheng; Qiannan Zhao; Hui-Yao Lan; Yu Huang; Song Wan; Yasuo Mori; Xiaoqiang Yao

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, Jul. 2015, Peer-reviewed

  
• Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering

  Akito Nakao; Takafumi Miki; Ken Shimono; Hiroaki Oka; Tomohiro Numata; Shigeki Kiyonaka; Kaori Matsushita; Hiroo Ogura; Tetsuhiro Niidome; Jeffrey L. Noebels; Minoru Wakamori; Keiji Imoto; Yasuo Mori

  PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Apr. 2015, Peer-reviewed

  
• Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure

  Yuko Yamada; Hideyuki Kinoshita; Koichiro Kuwahara; Yasuaki Nakagawa; Yoshihiro Kuwabara; Takeya Minami; Chinatsu Yamada; Junko Shibata; Kazuhiro Nakao; Kosai Cho; Yuji Arai; Shinji Yasuno; Toshio Nishikimi; Kenji Ueshima; Shiro Kamakura; Motohiro Nishida; Shigeki Kiyonaka; Yasuo Mori; Takeshi Kimura; Kenji Kangawa; Kazuwa Nakao

  CARDIOVASCULAR RESEARCH, Oct. 2014, Peer-reviewed

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• TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain

  Yongwoo Jang; Mi Hyun Lee; Jesun Lee; Jooyoung Jung; Sung Hoon Lee; Dong-Jin Yang; Byung Woo Kim; Hyeon Son; Boyoon Lee; Sunghoe Chang; Yasuo Mori; Uhtaek Oh

  PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Oct. 2014, Peer-reviewed

  
• TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P-2

  Nobuaki Takahashi; Sayaka Hamada-Nakahara; Yuzuru Itoh; Kazuhiro Takemura; Atsushi Shimada; Yoshifumi Ueda; Manabu Kitamata; Rei Matsuoka; Kyoko Hanawa-Suetsugu; Yosuke Senju; Masayuki X. Mori; Shigeki Kiyonaka; Daisuke Kohda; Akio Kitao; Yasuo Mori; Shiro Suetsugu

  NATURE COMMUNICATIONS, Sep. 2014, Peer-reviewed

  
• Transient Receptor Potential Melastatin 2 Protects Mice against Polymicrobial Sepsis by Enhancing Bacterial Clearance

  XiaoWei Qian; Tomohiro Numata; Kai Zhang; CaiXia Li; JinChao Hou; Yasuo Mori; XiangMing Fang

  ANESTHESIOLOGY, Aug. 2014, Peer-reviewed

  
• Involvement of TRPM2 and L-type Ca2+ channels in Ca2+ entry and cell death induced by hydrogen peroxide in rat beta-cell line RIN-5F

  Masakazu Ishii; Tamio Hagiwara; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF TOXICOLOGICAL SCIENCES, Apr. 2014

  
• ROLE OF EXERCISE IN MAINTAINING THE INTEGRITY OF THE NEUROMUSCULAR JUNCTION

  Hiroshi Nishimune; John A. Stanford; Yasuo Mori

  MUSCLE & NERVE, Mar. 2014, Peer-reviewed

  
• TRPM2 contributes to LPS/IFN gamma-induced production of nitric oxide via the p38/JNK pathway in microglia

  Takahito Miyake; Hisashi Shirakawa; Ayaka Kusano; Shinya Sakimoto; Masakazu Konno; Takayuki Nakagawa; Yasuo Mori; Shuji Kaneko

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2014, Peer-reviewed

  
• Transnitrosylation Directs TRPA1 Selectivity in N-Nitrosamine Activators

  Daisuke Kozai; Yoji Kabasawa; Maximilian Ebert; Shigeki Kiyonaka; Firman Yuko Otani; Tomohiro Numata; Nobuaki Takahashi; Yasuo Mori; Tomohiko Ohwada

  MOLECULAR PHARMACOLOGY, Jan. 2014, Peer-reviewed

  
• 蛍光性センサータンパク質による細胞内温度分布の可視化

  清中 茂樹; 坂口 怜子; 森 泰生

  生物物理, Jan. 2014

  
• Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner

  Yuki Nakamura; Xiuyu Shi; Tomohiro Numata; Yasuo Mori; Ryuji Inoue; Christoph Lossin; Tallie Z. Baram; Shinichi Hirose

  PLOS ONE, Dec. 2013, Peer-reviewed

  
• Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells

  Shigeki Kiyonaka; Taketoshi Kajimoto; Reiko Sakaguchi; Daisuke Shinmi; Mariko Omatsu-Kanbe; Hiroshi Matsuura; Hiromi Imamura; Takenao Yoshizaki; Itaru Hamachi; Takashi Morii; Yasuo Mori

  NATURE METHODS, Dec. 2013, Peer-reviewed

  
• TRPA1 detects environmental chemicals and induces avoidance behavior and arousal from sleep

  Toru Yonemitsu; Chiharu Kuroki; Nobuaki Takahashi; Yasuo Mori; Yuichi Kanmura; Hideki Kashiwadani; Youichirou Ootsuka; Tomoyuki Kuwaki

  SCIENTIFIC REPORTS, Oct. 2013, Peer-reviewed

  
• Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II

  Juan Shi; Naomi Geshi; Shinichi Takahashi; Shigeki Kiyonaka; Jun Ichikawa; Yaopeng Hu; Yasuo Mori; Yushi Ito; Ryuji Inoue

  JOURNAL OF PHYSIOLOGY-LONDON, Jun. 2013

  
• Avoidance of environmental gas irritants mediated by TRPA1

  Toru Yonemitsu; Nobuaki Takahashi; Yasuo Mori; Yuichi Kanmura; Tomoyuki Kuwaki

  FASEB JOURNAL, Apr. 2013, Peer-reviewed

  
• A210 Study on low sensitivity of Diamondback moth, Plutella xylostella, to Flubendiamide. (Resistance to Flubendiamide is associated with a mutation of the ryanodine receptor)

  Inukai Kayo; Sakata Kazuyuki; Mori Emiko; Kurokawa Tatsuki; Kimura Tasuku; Kiyonaka Shigeki; Mori Yasuo

  講演要旨集, Jan. 2013

  
• Nuclear life of the voltage-gated Cacnb4 subunit and its role in gene transcription regulation

  Michel Ronjat; Shigeki Kiyonaka; Maud Barbado; Michel De Waard; Yasuo Mori

  Channels, 2013, Peer-reviewed

  
• Mutation associated with autism modifies RIMS3-mediated modulation of voltage-dependent Ca2+ channels

  Yoshinori Takada; Mitsuru Hirano; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013

  
• TRPC3 contributes pressure overload-induced cardiac fibrosis

  Naoyuki Kitajima; Shigeki Kiyonaka; Yasuo Mori; Motohiro Nishida

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013

  
• Voltage-dependent calcium channel beta 4 subunit directly couples electrical activity to gene expression

  Seishiro Sawamura; Shigeki Kiyonaka; Takafumi Miki; Satoshi Akiyama; Michel Ronjat; Michel De Waard; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013

  
• Inhibition of TRPC channels underlies biological activities of a pyrazole compounds

  Yasuo Mori; Shigeki Kiyonaka; Motohiro Nishida

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013

  
• Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

  Abir Tadmouri; Shigeki Kiyonaka; Maud Barbado; Matthieu Rousset; Katell Fablet; Seishiro Sawamura; Eloi Bahembera; Karin Pernet-Gallay; Christophe Arnoult; Takafumi Miki; Karin Sadoul; Sylvie Gory-Faure; Caroline Lambrecht; Florian Lesage; Satoshi Akiyama; Saadi Khochbin; Sylvain Baulande; Veerle Janssens; Annie Andrieux; Ricardo Dolmetsch; Michel Ronjat; Yasuo Mori; Michel De Waard

  EMBO JOURNAL, Sep. 2012, Peer-reviewed

  
• Physical and functional interaction of the active zone protein CAST/ERC2 and the beta-subunit of the voltage-dependent Ca2+ channel

  Shigeki Kiyonaka; Hiroshi Nakajima; Yoshinori Takada; Yamato Hida; Toshinori Yoshioka; Akari Hagiwara; Isao Kitajima; Yasuo Mori; Toshihisa Ohtsuka

  JOURNAL OF BIOCHEMISTRY, Aug. 2012

  
• Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

  Hiroshi Nishimune; Tomohiro Numata; Jie Chen; Yudai Aoki; Yonghong Wang; Miranda P. Starr; Yasuo Mori; John A. Stanford

  PLOS ONE, Jun. 2012, Peer-reviewed

  
• Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

  Makiko Kashio; Takaaki Sokabe; Kenji Shintaku; Takayuki Uematsu; Naomi Fukuta; Noritada Kobayashi; Yasuo Mori; Makoto Tominaga

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2012, Peer-reviewed

  
• Utilization of Photoinduced Charge-Separated State of Donor-Acceptor-Linked Molecules for Regulation of Cell Membrane Potential and Ion Transport

  Tomohiro Numata; Tatsuya Murakami; Fumiaki Kawashima; Nobuhiro Morone; John E. Heuser; Yuta Takano; Kei Ohkubo; Shunichi Fukuzumi; Yasuo Mori; Hiroshi Imahori

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 2012, Peer-reviewed

  
• TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

  Kayo Haraguchi; Ai Kawamoto; Kouichi Isami; Sanae Maeda; Ayaka Kusano; Kayoko Asakura; Hisashi Shirakawa; Yasuo Mori; Takayuki Nakagawa; Shuji Kaneko

  JOURNAL OF NEUROSCIENCE, Mar. 2012, Peer-reviewed

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• The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death

  Masahiro Katano; Tomohiro Numata; Kripamoy Aguan; Yuji Hara; Shigeki Kiyonaka; Shinichiro Yamamoto; Takafumi Miki; Seishiro Sawamura; Toshimitsu Suzuki; Kazuhiro Yamakawa; Yasuo Mori

  CELL CALCIUM, Feb. 2012

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• The ?C splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation

  Tomohiro Numata; Kaori Sato; Jens Christmann; Romy Marx; Yasuo Mori; Yasunobu Okada; Frank Wehner

  JOURNAL OF PHYSIOLOGY-LONDON, Feb. 2012, Peer-reviewed

  
• 活性酸素で活性化されるTRPチャネル

  清中 茂樹; 高橋 重成; 森 泰生

  ファルマシア, Jan. 2012

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• B206 Characterization of the species-selectivity of flubendiamide using a molecular physiological approach.

  Mori Yasuo; Mori Emiko; Kurokawa Tatsuki; Inukai Kayo; Koyama Shohei; Kiyonaka Shigeki

  講演要旨集, Jan. 2012

  
• Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures

  Eiji Nakata; Fong Fong Liew; Chisana Uwatoko; Shigeki Kiyonaka; Yasuo Mori; Yousuke Katsuda; Masayuki Endo; Hiroshi Sugiyama; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012

  
• Functional impact of Munc18-1 on gating properties of voltage-dependent Ca2+ channels.

  Yoshinori Takada; Yoshitsugu Uriu; Hiroshi Nakajima; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012

  
• Inhibitory effect of Jak2 inhibitor AG490 on H2O2-induced Ca2+ entry via TRPM2 channels

  Hitomi Takashima; Masakazu Ishii; Kazunori Akimoto; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, Peer-reviewed

  
• Chronic inhibition of L/N-type Ca2+ channels prevents heart failure in mice

  Naoyuki Kitajima; Shota Saiki; Shizuka Aritomi; Tatsuya Ishikawa; Michio Nakaya; Yasuo Mori; Hitoshi Kurose; Motohiro Nishida

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, Peer-reviewed

  
• TRPA1 senses oxygen availability

  Nobuaki Takahashi; Shigeki Kiyonaka; Tomohiro Numata; Daisuke Kozai; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012

  
• Activation of TRPA1 channels by transnitrosylating reagents

  Daisuke Kozai; Maximilian Ebert; Fumika Karaki; Yuko Otani; Yoji Kabasawa; Nobuaki Takahashi; Tomohiro Numata; Shigeki Kiyonaka; Tomohiko Ohwada; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012

  
• Identification of oxygen sensitivity of TRPA1 channels using redox-sensitive chemical library

  Shigeki Kiyonaka; Nobuaki Takahashi; Daisuke Kozai; Tomohiro Numata; Yusuke Mizuno; Jun-ichi Yoshida; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012

  
• Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity

  Masakazu Ishii; Ryouta Iizuka; Yuji Kiuchi; Yasuo Mori; Shunichi Shimizu

  MOLECULAR AND CELLULAR BIOCHEMISTRY, Dec. 2011, Peer-reviewed

  
• Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain

  Kensaku Anraku; Teruhiko Inoue; Kenji Sugimoto; Kota Kudo; Yoshinari Okamoto; Takashi Morii; Yasuo Mori; Masami Otsuka

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2011, Peer-reviewed

  
• Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release

  Adriana Sumoza-Toledo; Ingo Lange; Hanna Cortado; Harivadan Bhagat; Yasuo Mori; Andrea Fleig; Reinhold Penner; Santiago Partida-Sanchez

  FASEB JOURNAL, Oct. 2011, Peer-reviewed

  
• TRPA1 underlies a sensing mechanism for O-2

  Nobuaki Takahashi; Tomoyuki Kuwaki; Shigeki Kiyonaka; Tomohiro Numata; Daisuke Kozai; Yusuke Mizuno; Shinichiro Yamamoto; Shinji Naito; Ellen Knevels; Peter Carmeliet; Toru Oga; Shuji Kaneko; Seiji Suga; Toshiki Nokami; Jun-ichi Yoshida; Yasuo Mori

  NATURE CHEMICAL BIOLOGY, Oct. 2011, Peer-reviewed

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• TRPC3/6 as Potentially Novel Therapeutic Targets for The Treatment of Pulmonary Arterial Hypertension

  Hideyuki Kinoshita; Koichiro Kuwahara; Shigeki Kiyonaka; Yasuo Mori; Yoshihiro Kuwabara; Satoru Usami; Yasuaki Nakagawa; Toshio Nishikimi; Kenji Ueshima; Kazuwa Nakao

  JOURNAL OF CARDIAC FAILURE, Sep. 2011, Peer-reviewed

  
• Transportsomes and channelsomes Are they functional units for physiological responses?

  Yasuo Mori; Shigeki Kiyonaka; Yoshikatsu Kanai

  CHANNELS, Sep. 2011, Peer-reviewed

  
• Roles of TRPM2 in oxidative stress

  Nobuaki Takahashi; Daisuke Kozai; Ryohei Kobayashi; Maximilian Ebert; Yasuo Mori

  CELL CALCIUM, Sep. 2011, Peer-reviewed

  
• Chemical Cell-Surface Receptor Engineering Using Affinity-Guided, Multivalent Organocatalysts

  Hangxiang Wang; Yoichiro Koshi; Daishiro Minato; Hiroshi Nonaka; Shigeld Kiyonaka; Yasuo Mori; Shinya Tsukiji; Itaru Hamachi

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Aug. 2011, Peer-reviewed

  
• TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts

  Naoyuki Kitajima; Kunihiro Watanabe; Sachio Morimoto; Yoji Sato; Shigeki Kiyonaka; Masahiko Hoshijima; Yasuhiro Ikeda; Michio Nakaya; Tomomi Ide; Yasuo Mori; Hitoshi Kurose; Motohiro Nishida

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2011, Peer-reviewed

  
• Functional Coupling of Rab3-interacting Molecule 1 (RIM1) and L-type Ca2+ Channels in Insulin Release

  Mara A. Gandini; Alejandro Sandoval; Ricardo Gonzalez-Ramirez; Yasuo Mori; Michel de Waard; Ricardo Felix

  JOURNAL OF BIOLOGICAL CHEMISTRY, May 2011, Peer-reviewed

  
• Rim1 modulates direct G-protein regulation of Ca(v)2.2 channels

  Norbert Weiss; Alejandro Sandoval; Shigeki Kyonaka; Ricardo Felix; Yasuo Mori; Michel De Waard

  PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Apr. 2011, Peer-reviewed

  
• Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5 '-Triphosphate in the Rat

  Megumi Sugihara; Hiromitsu Morita; Miho Matsuda; Hisanori Umebayashi; Shunichi Kajioka; Shinichi Ito; Motohiro Nishida; Ryosuke Inoue; Toshiko Futatsuki; Jun Yamazaki; Yasuo Mori; Ryuji Inoue; Yushi Ito; Kihachiro Abe; Masato Hirata

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2011, Peer-reviewed

  
• Expression of N-type calcium channels in human adrenocortical cells and their contribution to corticosteroid synthesis

  Shizuka Aritomi; Hirotaka Wagatsuma; Tomohiro Numata; Yoshitsugu Uriu; Yasuko Nogi; Akira Mitsui; Tomoyuki Konda; Yasuo Mori; Michihiro Yoshimura

  HYPERTENSION RESEARCH, Feb. 2011, Peer-reviewed

  
• 新規殺虫剤flubendiamideにおける昆虫選択的生物活性の分子基盤(虫害・線虫害防除の最前線から学ぶ)

  清中 茂樹; 加藤 賢太; 森 泰生

  Journal of pesticide science, Jan. 2011

  
• Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice

  Kunitoshi Uchida; Katsuya Dezaki; Boldbaatar Damdindorj; Hitoshi Inada; Tetsuya Shiuchi; Yasuo Mori; Toshihiko Yada; Yasuhiko Minokoshi; Makoto Tominaga

  DIABETES, Jan. 2011, Peer-reviewed

  
• TRP channel modulation by small molecules

  Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011

  
• Activation of TRPA1 channels by novel N-nitrosamines

  Daisuke Kozai; Ebert Maximilian; Fumika Karaki; Yuko Otani; Yoji Kabasawa; Nobuaki Takahashi; Tomohiro Numata; Shigeki Kiyonaka; Tomohiko Ohwada; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011

  
• Role of TRPM2 channels in bleomycin-induced pneumonitis

  Yukiko Kage; Risa Watanabe; Toshihito Hiroi; Takaharu Negoro; Yasuo Mori; Yuji Kiuchi; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011

  
• Suppression of fibrosis underlies prevention of dilated cardiomyopathy by TRPC channel inhibition

  Naoyuki Kitajima; Motohiro Nishida; Kunihiro Watanabe; Michio Nakaya; Shigeki Kiyonaka; Yoji Sato; Yasuo Mori; Hitoshi Kurose

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011

  
• Blockade of TRPC6 is a Novel Therapeutic Approach Against Pathological Cardiac Remodeling

  Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Hitoshi Kurose; Shigeki Kiyonaka; Yasuo Mori; Satoru Usami; Yasuaki Nakagawa; Kenji Ueshima; Kazuwa Nakao

  JOURNAL OF CARDIAC FAILURE, Sep. 2010

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• Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels

  Shinichiro Yamamoto; Nobuaki Takahashi; Yasuo Mori

  PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, Sep. 2010, Peer-reviewed

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• Rim2 alpha Determines Docking and Priming States in Insulin Granule Exocytosis

  Takao Yasuda; Tadao Shibasaki; Kohtaro Minami; Harumi Takahashi; Akira Mizoguchi; Yoshitsugu Uriu; Tomohiro Numata; Yasuo Mori; Jun-ichi Miyazaki; Takashi Miki; Susumu Seino

  CELL METABOLISM, Aug. 2010, Peer-reviewed

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• Rab3-interacting Molecule gamma Isoforms Lacking the Rab3-binding Domain Induce Long Lasting Currents but Block Neurotransmitter Vesicle Anchoring in Voltage-dependent P/Q-type Ca2+ Channels

  Yoshitsugu Uriu; Shigeki Kiyonaka; Takafumi Miki; Masakuni Yagi; Satoshi Akiyama; Emiko Mori; Akito Nakao; Aaron M. Beedle; Kevin P. Campbell; Minoru Wakamori; Yasuo Mori

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2010, Peer-reviewed

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• Treatment of global cerebral ischemia by virally-mediated shRNA suppression of TRPM7 channels

  H. Sun; M. F. Jackson; L. J. Martin; K. Jansen; L. Teves; H. Cui; S. Kiyonaka; Y. Mori; M. Jones; J. P. Forder; T. E. Golde; B. A. Orser; J. F. MacDonald; M. Tymianski

  STROKE, Jul. 2010

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• Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart

  Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jian; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Masataka Fujiwara; Yuko Yamada; Takeya Minami; Kenji Ueshima; Kazuwa Nakao

  CIRCULATION RESEARCH, Jun. 2010, Peer-reviewed

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• INHIBITION OF TRPC6 CHANNEL CONTRIBUTES TO THE ANTI-HYPERTROPHIC EFFECTS EXERTED BY NATRIURETIC PEPTIDES-GUANYLYL CYCLASE-A SIGNALING IN THE HEART

  K. Kuwahara; H. Kinoshita; M. Nishida; H. Kurose; R. Inoue; Y. Mori; K. Nakao

  JOURNAL OF HYPERTENSION, Jun. 2010

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• Treatment of Global Cerebral Ischemia by Virally-Mediated shRNA Suppression of TRPM7 Channels

  Hong-Shuo Sun; Michael F. Jackson; Loren J. Martin; Karen Jansen; Lucy Teves; Hong Cui; Shigeki Kiyonaka; Yasuo Mori; Michael Jones; Joan P. Forder; Todd E. Golde; Beverley A. Orser; John F. MacDonald; Michael Tymianski

  STROKE, Apr. 2010

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• A Missense Mutation of the Gene Encoding Voltage-Dependent Sodium Channel (Na(v)1.1) Confers Susceptibility to Febrile Seizures in Rats

  Tomoji Mashimo; Iori Ohmori; Mamoru Ouchida; Yukihiro Ohno; Toshiko Tsurumi; Takafumi Miki; Minoru Wakamori; Shizuka Ishihara; Takashi Yoshida; Akiko Takizawa; Megumi Kato; Masumi Hirabayashi; Masashi Sasa; Yasuo Mori; Tadao Serikawa

  JOURNAL OF NEUROSCIENCE, Apr. 2010, Peer-reviewed

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• Pharmacological Properties of Novel TRPC Channel Inhibitors

  Shigeki Kiyonaka; Kenta Kato; Motohiro Nishida; Yasuo Mori

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Mar. 2010

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• Ca2+ influx and protein scaffolding via TRPC3 sustain PKC beta and ERK activation in B cells

  Takuro Numaga; Motohiro Nishida; Shigeki Kiyonaka; Kenta Kato; Masahiro Katano; Emiko Mori; Tomohiro Kurosaki; Ryuji Inoue; Masaki Hikida; James W. Putney; Yasuo Mori

  JOURNAL OF CELL SCIENCE, Mar. 2010, Peer-reviewed

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• Differential Redox Regulation of ORAI Ion Channels: A Mechanism to Tune Cellular Calcium Signaling

  Ivan Bogeski; Carsten Kummerow; Dalia Al-Ansary; Eva C. Schwarz; Richard Koehler; Daisuke Kozai; Nobuaki Takahashi; Christine Peinelt; Desiree Griesemer; Monika Bozem; Yasuo Mori; Markus Hoth; Barbara A. Niemeyer

  SCIENCE SIGNALING, Mar. 2010, Peer-reviewed

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• Redox-sensitive TRP channels

  Yasuo Mori

  ENDOCRINE JOURNAL, Mar. 2010

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• Atrial and brain natriuretic peptides-guanylyl cyclase-A signaling pathway inhibits TRPC6-mediated pro-hypertrophic signaling in the hearts

  Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jiang; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Kenji Ueshima; Kazuwa Nakao

  ENDOCRINE JOURNAL, Mar. 2010

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• Involvement of Ca2+ Channel Synprint Site in Synaptic Vesicle Endocytosis

  Hiroyasu Watanabe; Takayuki Yamashita; Naoto Saitoh; Shigeki Kiyonaka; Akihiro Iwamatsu; Kevin P. Campbell; Yasuo Mori; Tomoyuki Takahashi

  JOURNAL OF NEUROSCIENCE, Jan. 2010, Peer-reviewed

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• TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

  Chieko Koike; Takehisa Obara; Yoshitsugu Uriu; Tomohiro Numata; Rikako Sanuki; Kentarou Miyata; Toshiyuki Koyasu; Shinji Ueno; Kazuo Funabiki; Akiko Tani; Hiroshi Ueda; Mineo Kondo; Yasuo Mori; Masao Tachibana; Takahisa Furukawa

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2010, Peer-reviewed

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• TRPM1: A vertebrate TRP channel responsible for retinal ON bipolar function

  Chieko Koike; Tomohiro Numata; Hiroshi Ueda; Yasuo Mori; Takahisa Furukawa

  Cell Calcium, 2010, Peer-reviewed

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• Development of FRET-based reporter for visualizing protein kinase C delta activity

  Taketoshi Kajimoto; Alyssa Wu; Yasuo Mori; Yumi Tohyama; Alexandra Newton

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• TRPM2 is essential for phagocytosis in macrophages

  Yuichi Sawaguchi; Taketoshi Kajimoto; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Participation of TRPM2 channels in bleomycin-induced lung inflammation and fibrosis

  Miki Takenaka; Hisano Endo; Toshihito Hiroi; Takaharu Negoro; Masayuki Ohbayashi; Yasuo Mori; Toshinori Yamamoto; Yuji Kiuchi; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Pathogenic C-terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7

  Shigeki Kiyonaka; Kyoko Miyagi; Kazunori Yamada; Takafumi Miki; Emiko Mori; Kenta Kato; Tomohiro Numata; Yuichi Sawaguchi; Toru Kimura; Yoshikatsu Kanai; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Munc18a associated with voltage-dependent Ca2+ channel beta subunits to facilitate voltage-dependent inactivation of P/Q type channels

  Hiroshi Nakajima; Yoshitsugu Uriu; Takafumi Miki; Satoshi Akiyama; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Implication of TRPM2 channels on myocardial ischemia-reperfusion injury in mice

  Toshihito Hiroi; Teruaki Wajima; Daisuke Kouzai; Takaharu Negoro; Yuji Kiuchi; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• TRPM2 functions as Ca2+ release channel in beta-cells

  Shinichiro Yamamoto; Ingo Lange; Andrea Fleig; Reinhold Penner; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• TRPC channels mediate cardiac hypertrophy

  Hitoshi Kurosei; Motohiro Nishida; Kenta Watanabe; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Inhibitory effect of lomerizine, a prophylactic drug for migraine, on H2O2-induced Ca2+ influx in cultured hippocampal neurons

  Ryota Iizuka; Masakazu Ishii; Yasuo Mori; Yuji Kiuchi

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• Cholinergic induced oscillation in hippocampus of tottering Ca2+ channel mutant mice

  Akito Nakao; Takafumi Miki; Ken Shimono; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010

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• An In Vivo Fluorescent Sensor Reveals Intracellular Ins(1,3,4,5)P-4 Dynamics in Single Cells

  Reiko Sakaguchi; Kazuki Tainaka; Naoko Shimada; Shun Nakano; Masafumi Inoue; Shigeki Kiyonaka; Yasuo Mori; Takashi Morii

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, Peer-reviewed

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• A novel interaction of cardiac VDCC with troponin

  Yudai Aoki; Takafume Miki; Shigeki Kiyonaka; Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010

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• Activation of TRPA1 channels by novel aliphatic N-nitrosamines

  Daisuke Kozai; Yoji Kabasawa; Nobuaki Takahashi; Shigeki Kiyonaka; Tomohiko Ohwada; Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010

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• Heat-sensitivity of TRPM2 channel is increased by H2O2 in murine macrophages

  Makiko Kashio; Takaaki Sokabe; Yasuo Mori; Makoto Tominaga

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010

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• A pathogenic C-terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7

  Tomohiro Numata; Shigeki Kiyonaka; Yoshikatsu Kanai; Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010

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• TRPM2 is a key player for insulin secretion

  Kunitoshi Uchida; Katsuya Dezaki; Boldbaatar Damdindorj; Yasuo Mori; Yasuhiko Minokoshi; Toshihiko Yada; Makoto Tominaga

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010

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• Elucidation of function and physiological significance from Thermococcus kodakaraensis TK2009

  Masahiro Katano; Shigeki Kiyonaka; Haruyuki Atomi; Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Peer-reviewed

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• Knockdown of Ca(v)2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice

  Hiromitsu Saito; Motohiro Okada; Takafumi Miki; Minoru Wakamori; Akira Futatsugi; Yasuo Mori; Katsuhiko Mikoshiba; Noboru Suzuki

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2009, Peer-reviewed

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• A Pathogenic C Terminus-truncated Polycystin-2 Mutant Enhances Receptor-activated Ca2+ Entry via Association with TRPC3 and TRPC7

  Kyoko Miyagi; Shigeki Kiyonaka; Kazunori Yamada; Takafumi Miki; Emiko Mori; Kenta Kato; Tomohiro Numata; Yuichi Sawaguchi; Takuro Numaga; Toru Kimura; Yoshikatsu Kanai; Mitsuhiro Kawano; Minoru Wakamori; Hideki Nomura; Ichiro Koni; Masakazu Yamagishi; Yasuo Mori

  JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2009, Peer-reviewed

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• Molecular Characterization of Flubendiamide Sensitivity in the Lepidopterous Ryanodine Receptor Ca2+ Release Channel

  Kenta Kato; Shigeki Kiyonaka; Yuichi Sawaguchi; Masanori Tohnishi; Takao Masaki; Noriaki Yasokawa; Yusuke Mizuno; Emiko Mori; Keisuke Inoue; Itaru Hamachi; Hiroshi Takeshima; Yasuo Mori

  BIOCHEMISTRY, Nov. 2009, Peer-reviewed

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• Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

  Hong-Shuo Sun; Michael F. Jackson; Loren J. Martin; Karen Jansen; Lucy Teves; Hong Cui; Shigeki Kiyonaka; Yasuo Mori; Michael Jones; Joan P. Forder; Todd E. Golde; Beverley A. Orser; John F. MacDonald; Michael Tymianski

  NATURE NEUROSCIENCE, Oct. 2009, Peer-reviewed

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• A single circularly permuted GFP sensor for inositol-1,3,4,5-tetrakisphosphate based on a split PH domain

  Reiko Sakaguchi; Takashi Endoh; Seigo Yamamoto; Kazuki Tainaka; Kenji Sugimoto; Nobutaka Fujieda; Shigeki Kiyonaka; Yasuo Mori; Takashi Morii

  BIOORGANIC & MEDICINAL CHEMISTRY, Oct. 2009, Peer-reviewed

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• Cardiac Natriuretic Peptides Inhibit TRPC6-Mediated Prohypertrophic Signaling

  Hideyuki Kinoshita; Koichiro Kuwahara; Ryuji Inoue; Motohiro Nishida; Hitoshi Kurose; Shigeki Kiyonaka; Yasuo Mori; Masaki Harada; Masao Murakami; Yasuaki Nakagawa; Shinji Yasuno; Satoru Usami; Masataka Fujiwara; Yoshihiro Kuwabara; Takeya Minami; Yuko Yamada; Kenji Ueshima; Kazuwa Nakao

  CIRCULATION RESEARCH, Sep. 2009, Peer-reviewed

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• Synergistic Activation of Vascular TRPC6 Channel by Receptor and Mechanical Stimulation via Phospholipase C/Diacylglycerol and Phospholipase A(2)/omega-Hydroxylase/20-HETE Pathways

  Ryuji Inoue; Lars J. Jensen; Zhong Jian; Juan Shi; Lin Hai; Andrew I. Lurie; Freja H. Henriksen; Max Salomonsson; Hiromitsu Morita; Yasuhiro Kawarabayashi; Masayuki Mori; Yasuo Mori; Yushi Ito

  CIRCULATION RESEARCH, Jun. 2009, Peer-reviewed

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• Tetrameric Orai1 Is a Teardrop-shaped Molecule with a Long, Tapered Cytoplasmic Domain

  Yuusuke Maruyama; Toshihiko Ogura; Kazuhiro Mio; Kenta Kato; Takeshi Kaneko; Shigeki Kiyonaka; Yasuo Mori; Chikara Sato

  JOURNAL OF BIOLOGICAL CHEMISTRY, May 2009, Peer-reviewed

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• STIM protein coupling in the activation of Orai channels

  Youjun Wang; Xiaoxiang Deng; Yandong Zhou; Eunan Hendron; Salvatore Mancarella; Michael F. Ritchie; Xiang D. Tang; Yoshihiro Baba; Tomohiro Kurosaki; Yasuo Mori; Jonathan Soboloff; Donald L. Gill

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2009, Peer-reviewed

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• TRPM2 Functions as a Lysosomal Ca2+-Release Channel in beta Cells

  Ingo Lange; Shinichiro Yamamoto; Santiago Partida-Sanchez; Yasuo Mori; Andrea Fleig; Reinhold Penner

  SCIENCE SIGNALING, May 2009, Peer-reviewed

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• Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

  Shigeki Kiyonaka; Kenta Kato; Motohiro Nishida; Kazuhiro Mio; Takuro Numaga; Yuichi Sawaguchi; Takashi Yoshida; Minoru Wakamori; Emiko Mori; Tomohiro Numata; Masakazu Ishii; Hiroki Takemoto; Akio Ojida; Kenta Watanabe; Aya Uemura; Hitoshi Kurose; Takashi Morii; Tsutomu Kobayashi; Yoji Sato; Chikara Sato; Itaru Hamachi; Yasuo Mori

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2009, Peer-reviewed

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• Changes in Temperature Preferences and Energy Homeostasis in Dystroglycan Mutants

  Ken-ichi Takeuchi; Yoshiro Nakano; Utako Kato; Mizuho Kaneda; Masako Aizu; Wakae Awano; Shigenobu Yonemura; Shigeki Kiyonaka; Yasuo Mori; Daisuke Yamamoto; Masato Umeda

  SCIENCE, Mar. 2009, Peer-reviewed

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• Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

  Michelle E. Olah; Michael F. Jackson; Hongbin Li; Yael Perez; Hong-Shuo Sun; Shigeki Kiyonaka; Yasuo Mori; Michael Tymianski; John F. MacDonald

  JOURNAL OF PHYSIOLOGY-LONDON, Mar. 2009, Peer-reviewed

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• Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators

  Daisuke Kozai; Nobuaki Takahashi; Yusuke Mizuno; Shinichiro Yamamoto; Shigeki Kiyonaka; Takahiro Shibata; Koji Uchida; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Deficit of TRPM2 channels reduces myocardial ischemia-reperfusion injury in mice

  Toshihito Hiroi; Teruaki Wajima; Yuji Kaneko; Takaharu Negoro; Yuji Kiuchi; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Potentiation of TRPC5 channel activity by Ca2+

  Minoru Wakamori; Takashi Yoshida; Shinichiro Yamamoto; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Functional impact of RIMs on gating of voltage-dependent Ca2+channels

  Yoshitsugu Uriu; Minoru Wakamori; Koji Yamazaki; Miki Takafumi; Shigeki Kiyonaka; Emiko Mori; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Sympathetic regulation of arterial tonus via TRPC3/NCX1 coupling

  Satomi Kita; Takuya Yoda; Yuji Arai; Issei Komuro; Ryuji Inoue; Kenta Kato; Shigeki Kiyonaka; Yasuo Mori; Takahiro Iwamoto

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Working mechanism of flubendiamide, a novel ryanodine receptor activator

  Yuichi Sawaguchi; Yusuke Mizuno; Kenta Kato; Shigeki Kiyonaka; Emiko Mori; Takao Masaki; Hiroshi Takeshima; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Inhibitory effect of Jaks inhibitor AG490 on hydrogen peroxide-induced activation of TRPM2 channels

  Yuko Kakihana; Yuji Kaneko; Tarnio Hagiwara; Masakazu Ishii; Shinichiro Yamamoto; Takashi Yoshida; Toshihito Hiroi; Yasuo Mori; Yuji Kiuchi; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Involvement of TRPM2 channels in the early vascular permeability induced by acetic acid and zymosan

  Yuji Kaneko; Yuko Kakihana; Toshihito Hiroi; Takaharu Negoro; Disuke Kamei; Masakazu Ishii; Yuji Kiuchi; Yasuo Mori; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• A critical role of TRPM2 channel in inflammatory and neuropathic pain

  Ai Kawamoto; Sanae Maeda; Hisashi Shirakawa; Takayuki Nakagawa; Yasuo Mori; Shuji Kaneko

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Selective and direct inhibition of TRPC3 channels underlies biological activities of the novel pyrazole compound

  Kenta Kato; Shigeki Kiyonaka; Motohiro Nishida; Kazuhiro Mio; Tomohiro Numata; Yuichi Sawaguchi; Emiko Mori; Chikara Sato; Itaru Hamachi; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Regulation of hypertrophic signaling pathway by functional interaction between G protein-coupled receptor and TRPC channels

  Motohiro Nishida; Yoji Sato; Michio Nayaka; Ryuji Inoue; Yasuo Mori; Hitoshi Kurose

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Reactive oxygen species-induced signal amplification and chronic inflammation mediated by TRPM2 channels

  Yasuo Mori; Shinichiro Yamamoto; Shigeki Kiyonaka; Nobuaki Takahashi; Yuji Kiuchi; Shunichi Shimizu

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Peer-reviewed

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• Hyperthermia-induced seizure-susceptible rats: a novel model of febrile seizures

  Tomoji Mashimo; Iori Ohmori; Mamoru Ouchida; Yukihiro Ohno; Toshiko Tsurumi; Takafumi Miki; Minoru Wakamori; Yasuo Mori; Tadao Serikawa

  NEUROSCIENCE RESEARCH, 2009

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• SELECTIVE AND DIRECT INHIBITION OF TRPC3 CHANNELS UNDERLIES BIOLOGICAL ACTIVITIES OF A PYRAZOLE COMPOUND

  Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• MACROPHAGE PRODUCED REACTIVE OXYGEN SPECIES REGULATE CALCIUM-DEPENDENT T-CELL ACTIVATION

  Ivan Bogeski; Carsten Kummerow; Dalia Al-Ansary; Christine Peinelt; Yasuo Mori; Markus Hoth; Barbara Niemeyer

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• FORMATION OF PURINERGIC P2Y(2) RECEPTOR-TRPC5-eNOS PROTEIN COMPLEXES DEFINES ATP-INDUCED ANTI-HYPERTROPHIC ACTIONS IN RAT CARDIOMYOCYTES

  Miyuki Toyotaka; Motohiro Nishida; Michio Nakaya; Ryuji Inoue; Yasuo Mori; Hitoshi Kurose

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• REGULATORY ROLE OF THE INTERACTION BETWEEN ACTN4 AND ABCF2 IN CELL VOLEME REGULATION AND VOLUME-SENSITIVE ANION CHANNEL

  Yuhko Ando-Akatsuka; Takahiro Shimizu; Tomohiro Numata; Yasuo Mori; Yasunobu Okada

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• FACILITATION OF TRPC5 CHANNEL BY CALCIUM

  Minoru Wakamori; Takashi Yoshida; Shinichiro Yamamoto; Yasuo Mori

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• REGULATION OF ARTERIAL TONE BY TRPC3/NCX1 COUPLING

  Satomi Kita; Takuya Iyoda; Yuji Arai; Issei Komuro; Ryuji Inoue; Kenta Kato; Shigeki Kiyonaka; Yasuo Mori; Takahiro Iwamoto

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• Ca(v)2.1 DYSFUNCTION MAY BE A GENETIC MODIFIER OF SEVERE MYOCLONIC EPILEPSY IN INFANCY

  Iori Ohmori; Mamoru Ouchida; Takafumi Miki; Nobuyoshi Mimaki; Shigeki Kiyonaka; Teiichi Nishiki; Kazuhito Tomizawa; Yasuo Mori; Hideki Matsui

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

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• A CACNB4 mutation shows that altered Ca(v)2.1 function may be a genetic modifier of severe myoclonic epilepsy in infancy

  Iori Ohmori; Mamoru Ouchida; Takafumi Miki; Nobuyoshi Mimaki; Shigeki Kiyonaka; Teiichi Nishiki; Kazuhito Tomizawa; Yasuo Mori; Hideki Matsui

  NEUROBIOLOGY OF DISEASE, Dec. 2008, Peer-reviewed

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• Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6

  Shinichi Takahashi; Hai Lin; Naomi Geshi; Yasuo Mori; Yasuhiro Kawarabayashi; Noboru Takami; Masayuki X. Mori; Akira Honda; Ryuji Inoue

  JOURNAL OF PHYSIOLOGY-LONDON, Sep. 2008, Peer-reviewed

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• Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators

  Nobuaki Takahashi; Yusuke Mizuno; Daisuke Kozai; Shinichiro Yamamoto; Shigeki Kiyonaka; Takahiro Shibata; Koji Uchida; Yasuo Mori

  CHANNELS, Jul. 2008, Peer-reviewed

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• Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies

  T. Miki; T. A. Zwingman; M. Wakamori; C. M. Lutz; S. A. Cook; D. A. Hosford; K. Herrup; C. F. Fletcher; Y. Mori; W. N. Frankel; V. A. Letts

  NEUROSCIENCE, Jul. 2008, Peer-reviewed

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• TRPM2-mediated Ca(2+) influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

  Shinichiro Yamamoto; Shunichi Shimizu; Shigeki Kiyonaka; Nobuaki Takahashi; Teruaki Wajima; Yuji Hara; Takaharu Negoro; Toshihito Hiroi; Yuji Kiuchi; Takaharu Okada; Shuji Kaneko; Ingo Lange; Andrea Fleig; Reinhold Penner; Miyuki Nishi; Hiroshi Takeshima; Yasuo Mori

  NATURE MEDICINE, Jul. 2008, Peer-reviewed

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• Characterization of a tobacco TPK-type K+ channel as a novel tonoplast K+ channel using yeast tonoplasts

  Shin Hamamoto; Junichiro Marui; Ken Matsuoka; Kyohei Higashi; Kazuei Igarashi; Tsuyoshi Nakagawa; Teruo Kuroda; Yasuo Mori; Yoshiyuki Murata; Yoichi Nakanishi; Masayoshi Maeshima; Isamu Yabe; Nobuyuki Uozumi

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2008, Peer-reviewed

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• Direct activation of the ion channel TRPA1 by 15d-PGJ(2), an endogenous ligand

  Yusuke Mizuno; Nobuaki Takahashi; Shinitiroh Yamamoto; Takashi Shibata; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008

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• Functional impact of RIM family on gating of voltage-dependent Ca2+ channels

  Yoshitsugu Uriu; Minoru Wakamori; Shigeki Kiyonaka; Satoshi Akiyama; Takafumi Miki; Emiko Mori; Yasuo Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008

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• Physiological role of the oxidative stress-sensitive activation of TRPM2 Ca2+ channels

  Shinichiro Yamamoto; Shigeki Kiyonaka; Nobuaki Takahashi; Yasuo Mori

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2008

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• The functional analysis of TRPM1 in mammalian retinal bipolar cells

  Chieko Koike; Takehisa Obara; Yukitsugu Uriu; Kentaro Miyata; Toshiyuki Koyasu; Akiko Tani; Mineo Kondo; Yasuo Mori; Masao Tachibana; Takahisa Furukawa

  NEUROSCIENCE RESEARCH, 2008, Peer-reviewed

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• The functional analysis of TRPM1 in mammalian retinal bipolar cells

  Chieko Koike; Takehisa Obara; Yukitsugu Uriu; Kentaro Miyata; Toshiyuki Koyasu; Akiko Tani; Mineo Kondo; Yasuo Mori; Masao Tachibana; Takahisa Furukawa

  NEUROSCIENCE RESEARCH, 2008

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• Design and synthesis of biotinylated inositol phosphates relevant to the biotin-avidin techniques

  Kensaku Anraku; Teruhiko Inoue; Kenji Sugimoto; Takashi Morii; Yasuo Mori; Yoshinari Okamoto; Masami Otsuka

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, Peer-reviewed

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• Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel

  Yuusuke Maruyama; Toshihiko Ogura; Kazuhiro Mio; Shigeki Kiyonaka; Kenta Kato; Yasuo Mori; Chikara Sato

  JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2007, Peer-reviewed

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• Facilitation of H2O2-induced A172 human glioblastoma cell death by insertion of oxidative stress-sensitive TRPM2 channels

  Masakazu Ishii; Akinori Oyama; Tamio Hagiwara; Akira Miyazaki; Yasuo Mori; Yuji Kiuchi; Shunichi Shimizu

  ANTICANCER RESEARCH, Nov. 2007, Peer-reviewed

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• Regulatory role of neuron-restrictive silencing factor in expression of TRPC1

  Takayoshi Ohba; Hiroyuki Watanabe; Yoichiro Takahashi; Takashi Suzuki; Ichiro Miyoshi; Shinnsuke Nakayama; Eisaku Satoh; Kenji Iino; Hironobu Sasano; Yasuo Mori; Sadao Kuromitsu; Keiichi Imagawa; Yoshihiko Saito; Toshihiko Iijima; Hiroshi Ito; Manabu Murakami

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2006

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• A Ca(V)2.1 calcium channel mutation rocker reduces the number of postsynaptic AMPA receptors in parallel fiber-Purkinje cell synapses

  Takashi Kodama; Yuko Itsukaichi-Nishida; Yugo Fukazawa; Minoru Wakamori; Mariko Miyata; Elek Molnar; Yasuo Mori; Ryuichi Shigemoto; Keiji Imoto

  EUROPEAN JOURNAL OF NEUROSCIENCE, Dec. 2006

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• Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum

  Yoshihiro Baba; Kenji Hayashit; Yoko Fujii; Akiko Mizushima; Hiroshi Watarai; Minoru Wakamori; Takuro Numaga; Yasuo Mori; Masamitsu Iino; Masaki Hikida; Tomohiro Kurosaki

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2006

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• TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

  Naoya Onohara; Motohiro Nishida; Ryuji Inoue; Hiroyuki Kobayashi; Hideki Sumimoto; Yoji Sato; Yasuo Mori; Taku Nagao; Hitoshi Kurose

  EMBO JOURNAL, Nov. 2006

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• Nitric oxide activates TRP channels by cysteine S-nitrosylation

  Takashi Yoshida; Ryuji Inoue; Takashi Morii; Nobuaki Takahashi; Shinichiro Yamamoto; Yuji Hara; Makoto Tominaga; Shunichi Shimizu; Yoji Sato; Yasuo Mori

  NATURE CHEMICAL BIOLOGY, Nov. 2006

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• TRP channels: Molecular diversity and physiological function

  Motohiro Nishida; Yuji Hara; Takashi Yoshida; Ryuji Inoue; Yasuo Mori

  MICROCIRCULATION, Oct. 2006

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• Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells

  Hideaki Oike; Minoru Wakamori; Yasuo Mori; Hiroki Nakanishi; Ryo Taguchi; Takumi Misaka; Ichiro Matsumoto; Keiko Abe

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, Sep. 2006

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• Native TRPC7 channel activation by an inositol trisphosphate receptor-dependent mechanism

  Guillermo Vazquez; Gary St. J. Bird; Yasuo Mori; James W. Putney

  JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 2006

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• Oligo-Asp Tag/Zn(II) complex probe as a new pair for labeling and fluorescence imaging of proteins

  Akio Ojida; Kei Honda; Daisuke Shinmi; Shigeki Kiyonaka; Yasuo Mori; Itaru Hamachi

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Aug. 2006

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• Blocker-resistant presynaptic voltage-dependent Ca2+ channels underlying glutamate release in mice nucleus tractus solitarii

  Koji Yamazaki; Eiji Shigetomi; Ryo Ikeda; Motohiro Nishida; Shiqeki Kiyonaka; Yasuo Mori; Fusao Kato

  BRAIN RESEARCH, Aug. 2006

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• Extracellular-added ADP-ribose increases intracellular free Ca2+ concentration through Ca2+ release from stores, but not through TRPM2-mediated Ca2+ entry, in rat beta-cell line RIN-5F

  M Ishii; S Shimizu; T Hagiwara; T Wajima; A Miyazaki; Y Mori; Y Kiuchi

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Jun. 2006

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• Intracellular-produced hydroxyl radical mediates H2O2-induced Ca2+ influx and cell death in rat beta-cell line RIN-5F

  M Ishii; S Shimizu; Y Hara; T Hagiwara; A Miyazaki; Y Mori; Y Kiuchi

  CELL CALCIUM, Jun. 2006

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• A critical role of TRPM2 in neuronal cell death hy hydrogen peroxide

  S Kaneko; S Kawakami; Y Hara; M Wakamori; E Itoh; T Minami; Y Takada; T Kume; H Katsuki; Y Mori; A Akaike

  JOURNAL OF PHARMACOLOGICAL SCIENCES, May 2006

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• TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

  Kazuya Togashi; Yuji Hara; Tomoko Tominaga; Tomohiro Higashi; Yasunobu Konishi; Yasuo Mori; Makoto Tominaga

  EMBO JOURNAL, May 2006

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• A functional AMPA receptor-calcium channel complex in the postsynaptic membrane

  MG Kang; CC Chen; M Wakamori; Y Hara; Y Mori; KP Campbell

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2006

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• Discovery of novel TRPC channel blockers

  S Kiyonaka; M Nishida; K Kato; M Wakamori; E Mori; M Ishii; T Kobayashi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• The physiological significance of diacylglycerol-activated TRPC3 channels in B cell receptor signalling

  T Numaga; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• Impaired transmission of parallel fiber-Purkinje cell synapses involves postsynaptic alterations in Ga(V)2.1 mutant mice, rocker

  Keiji Imoto; Takashi Kodama; Ryuichi Shigemoto; Yugo Fukazawa; Yasuo Mori

  NEUROSCIENCE RESEARCH, 2006

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• Discovery of a novel modulator for insect ryanodine receptor

  K Kato; S Kiyonaka; E Mori; T Masaki; N Yasokawa; H Hamaguchi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• Altered synaptic transmission in APPswe and PS1 double transgenic mice

  Y Goto; T Niidome; K Shimono; N Taniuchi; Y Mori; T Kihara; H Sugimoto

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• Three kinds of modulations of P/Q-type (Ca(v)2.1) Ca2+ channel activity by metabotropic glutamate receptor subtype 1a (mGluR1a)

  K Yamazaki; M Wakamori; N Shigetada; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• Physiological role and activation mechanism of the oxidative stress-susceptible TRPM2 Ca2+ channel in immunocytes

  S Yamamoto; S Shimizu; M Ishii; Y Hara; T Hagiwara; T Negoro; M Nishida; T Tobe; Y Kiuchi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• Inhibitory effect of lomerizine on TRP channel-mediated calcium influx

  M Ishii; S Shimizu; Y Mori; Y Kiuchi

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006

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• The role of canonical transient receptor potential 7 in B-cell receptor-activated channels

  JP Lievremont; T Numaga; G Vazquez; L Lemonnier; Y Hara; E Mori; M Trebak; SE Moss; GS Bird; Y Mori; JW Putney

  JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2005

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• Effects of calmodulin and Ca2+ channel blockers on omega-conotoxin GVI a binding to crude membranes from alpha(1B) subunit (Ca(v)2.2) expressed BHK cells and mice brain lacking the alpha(1B) subunits

  T Wada; T Imanishi; A Kawaguchi; MX Mori; Y Mori; K Imoto; S Ichida

  NEUROCHEMICAL RESEARCH, Aug. 2005

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• The non-selective cation-permeable channel TRPC3 is a tetrahedron with a cap on the large cytoplasmic end

  K Mio; T Ogura; Y Hara; Y Mori; C Sato

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2005

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• Heat-evoked activation of ion channel, TRPM2

  K Togashi; Y Hara; T Higashi; Y Konishi; T Tominaga; Y Mori; M Tominaga

  FASEB JOURNAL, Mar. 2005

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• FPL 64176 modification of Ca(V)1.2 L-type calcium channels: Dissociation of effects on ionic current and gating current

  SI McDonough; Y Mori; BP Bean

  BIOPHYSICAL JOURNAL, Jan. 2005

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• Association of TRPM12 channel with a novel EF-hand protein, EFHC1

  Y Hara; A Kripamoy; M Katano; K Yamakawa; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• C-terminal dependent activation of vascular receptor-operated Ca2+ entry channel TRPC6

  R Inoue; J Shi; A Honda; Y Mori; Y Ito

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• Cholinergic oscillation in hippocampus of tottering calcium channel mutant mice

  T Miki; K Shimono; S Kiyonaka; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• TRP channels and novel calcium antagonists

  Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• A new high-throughput electrophysiology platform using voltage clamp noise analysis

  M Taketani; T Yoshida; M Kojima; H Jiko; M Nakatani; N Katayama; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• Identification of the gene responsible for juvenile myoclonic epilepsy.

  T Suzuki; AV Delgado-Escueta; K Aguan; J Shi; Y Hara; M Nishida; T Numata; T Takeuchi; DS Bai; Y Inoue; M Osawa; S Kaneko; H Oguni; Y Mori; K Yamakawa

  EPILEPSIA, 2005

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• Physiological role and activation mechanism of the oxidative stress-susceptible TRPM2 Ca2+ channel in immunocytes

  S Yamamoto; S Shimizu; M Ishii; T Hagiwara; Y Hara; T Negoro; M Nishida; T Tobe; Y Kiuchi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• TRPC5 is activated by endogenous NO through direct cystein oxidation

  T Yoshida; Y Iinuma; M Nishida; Y Hara; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• Analysis of BCR-induced calcium signaling in TRPC3-deficient DT40 cells

  T Numaga; K Imoto; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005

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• Nitric-oxide-induced activation of TRPC5 Ca2+ channel mediates a positive feedback loop in receptor-induced eNOS signaling

  Y Mori; T Yoshida; Y Hara; S Yamamoto

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2005

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• Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells

  J Shi; E Mori; Y Mori; M Mori; J Li; Y Ito; R Inoue

  JOURNAL OF PHYSIOLOGY-LONDON, Dec. 2004

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• Activation of RasGRP3 by phosphorylation of Thr-133 is required ifor B cell receptor-mediated Ras activation

  Y Aiba; M Oh-hora; S Kiyonaka; Y Kimura; A Hijikata; Y Mori; T Kurosaki

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2004

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• Polyglutamine repeats of spinocerebellar ataxia 6 impair the cell-death-preventing effect of Ca(v)2.1 Ca2+ channel-loss-of-function cellular model of SCA6

  Z Matsuyama; NK Yanagisawa; Y Aoki; JL Black; VA Lennon; Y Mori; K Imoto; T Inuzuka

  NEUROBIOLOGY OF DISEASE, Nov. 2004

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• Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells

  T Hanano; Y Hara; J Shi; H Morita; C Umebayashi; E Mori; H Sumimoto; Y Ito; Y Mori; R Inoue

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2004

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• Mutations in EFHC1 cause juvenile myoclonic epilepsy

  T Suzuki; AV Delgado-Escueta; K Aguan; ME Alonso; J Shi; Y Hara; M Nishida; T Numata; MT Medina; T Takeuchi; R Morita; DS Bai; S Ganesh; Y Sugimoto; J Inazawa; JN Bailey; A Ochoa; A Jara-Prado; A Rasmussen; J Ramos-Peek; S Cordova; F Rubio-Donnadieu; Y Inoue; M Osawa; S Kaneko; H Oguni; Y Mori; K Yamakawa

  NATURE GENETICS, Aug. 2004

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• Novel real-time sensors to quantitatively assess in vivo inositol 1,4,5-trisphosphate production in intact cells

  K Sugimoto; M Nishida; M Otsuka; K Makino; K Ohkubo; Y Mori; T Morii

  CHEMISTRY & BIOLOGY, Apr. 2004

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• Visualization of muscarinic acetylcholine receptor using post-photoaffinity labeling modification (P-PLAM) method in cells

  S Kiyonaka; M Nishida; J Fuchimoto; I Hamachi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Implication of Ca2+ entry through oxidative stress sensitive TRPM2 channel on IL-8 production by H2O2 in U937 cells

  S Yamamoto; S Shimizu; T Negoro; M Ishii; Y Hara; M Nishida; T Tobe; Y Mori; Y Kiuchi

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Potent inhibition of B cell receptor signaling by a novel Ca2+ channel blocker

  M Nishida; S Kiyonaka; T Mizumoto; T Numaga; E Mori; M Ishii; T Kobayashi; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Mechanosensitive potentiation of receptor-activated TRPC6 channels

  R Inoue; Y Mori; Y Ito

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Cystine oxidation activates Ca2+-permeable cation channel TRPC5

  T Yoshida; M Nishida; Y Hara; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Physiological role of the oxidative stress-susceptible TRPM2 Ca2+ channel in immunocytes.

  S Yamamoto; S Shimizu; M Ishii; T Hagiwara; Y Hara; T Negoro; M Nishida; T Tobe; Y Mori; Y Kiuchi

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2004

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• Possible involvement of hydroxyl radical in H2O2-induced calcium influx through TRPM2 channel

  M Ishii; Y Hara; S Yamamoto; Y Mori; S Shimizu; Y Kiuchi

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Structural and functional characterization of Nudix motif in TRPM2 channel

  Y Hara; M Katano; Y Honjyou; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Polycystin-L is a voltage dependent and non-selective cation channel

  K Yamada; H Nomura; Y Itsukaichi; E Mori; K Saito; I Koni; H Mabuchi; A Hazama; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2004

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• Decrease in tetrahydrobiopterin content promotes L-arginine-induced elevation of cytosolic calcium concentration in insulin-secreting cells

  T Watabe; M Ishii; Y Mori; S Shimizu; Y Kiuchi

  PTERIDINES, Dec. 2003

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• Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLC gamma 2 in B lymphocytes

  M Nishida; K Sugimoto; Y Hara; E Mori; T Morii; T Kurosaki; Y Mori

  EMBO JOURNAL, Sep. 2003

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• Direct interaction and functional coupling between metabotropic glutamate receptor subtype 1 and voltage-sensitive Ca(v)2.1 Ca2+ channel

  J Kitano; M Nishida; Y Itsukaichi; Minami, I; M Ogawa; T Hirano; Y Mori; S Nakanishi

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2003

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• Functional reassembly of a split PH domain

  K Sugimoto; Y Mori; K Makino; K Ohkubo; T Morii

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 2003

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• Amplification of Ca2+ signaling by Ca2+ entry-dependent translocation and activation of phospholipase C gamma 2 in B lymphocytes.

  M Nishida; K Sugimoto; Y Hara; E Mori; T Morii; T Kurosaki; Y Mori

  JOURNAL OF PHARMACOLOGICAL SCIENCES, 2003

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• A new fluorescent biosensor for inositol trisphosphate

  T Morii; K Sugimoto; K Makino; M Otsuka; K Imoto; Y Mori

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Feb. 2002

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• Structure-based design of a leucine zipper protein with new DNA contacting region

  T Morii; S Sato; M Hagihara; Y Mori; K Imoto; K Makino

  BIOCHEMISTRY, Feb. 2002

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Misc.

• The functional analysis of TRPM1 in mammalian retinal bipolar cells

  Chieko Koike; Takehisa Obara; Yukitsugu Uriu; Kentaro Miyata; Toshiyuki Koyasu; Akiko Tani; Mineo Kondo; Yasuo Mori; Masao Tachibana; Takahisa Furukawa

  NEUROSCIENCE RESEARCH, 2008, Peer-reviewed

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• Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

  Makiko Kashio; Takaaki Sokabe; Kenji Shintaku; Takayuki Uematsu; Naomi Fukuta; Noritada Kobayashi; Yasuo Mori; Makoto Tominaga

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2012, Peer-reviewed

  
• "TRPA1 チャネルの酸素感受機構の解明”

  沼田朋大; 高橋重成; 清中茂樹; 香西大輔; 森泰生

  第89 回日本生理学会大会, 2012.3.29, 2012, Peer-reviewed

  
• “血中酸素飽和度を感知するTRPAl ”

  高橋重成; 清中茂樹; 沼田朋大; 香西大輔; 森泰生

  第85回日本薬理学会, 2012.3.14, 2012, Peer-reviewed

  
• Development of the immobilization technology of functional proteins on DNA origami

  E. Nakata; C. Uwatoko; F.F. Liew; S. Kiyonaka; Y. Mori; Y. Katsuta; M. Endo; H. Sugiyama; T. Morii

  The 38th International Symposium on Nucleic Acid Chemistry，Hokkaido，2011.11.9-11, 2011, Peer-reviewed

  
• “TRP チャネルによる酸素感受性”

  高橋重成; 森泰生

  第84回日本生化学会大会，2011.9.11, 2011, Peer-reviewed

  
• DNA origami上への機能性タンパク質固定化技術の開発

  中田栄司; 上床知佐奈; 劉芳芳; 清中茂樹; 森泰生; 勝田陽介; 遠藤政幸; 杉山弘; 森井孝

  第5回バイオ関連化学シンポジウム，つくば国際会議場「エポカルつくば」，2011.9.12-14, 2011, Peer-reviewed

  
• TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

  Chieko Koike; Takehisa Obara; Yoshitsugu Uriu; Tomohiro Numata; Rikako Sanuki; Kentarou Miyata; Toshiyuki Koyasu; Shinji Ueno; Kazuo Funabiki; Akiko Tani; Hiroshi Ueda; Mineo Kondo; Yasuo Mori; Masao Tachibana; Takahisa Furukawa

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2010, Peer-reviewed

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• STIM protein coupling in the activation of Orai channels

  Youjun Wang; Xiaoxiang Deng; Yandong Zhou; Eunan Hendron; Salvatore Mancarella; Michael F. Ritchie; Xiang D. Tang; Yoshihiro Baba; Tomohiro Kurosaki; Yasuo Mori; Jonathan Soboloff; Donald L. Gill

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2009, Peer-reviewed

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• Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

  Shigeki Kiyonaka; Kenta Kato; Motohiro Nishida; Kazuhiro Mio; Takuro Numaga; Yuichi Sawaguchi; Takashi Yoshida; Minoru Wakamori; Emiko Mori; Tomohiro Numata; Masakazu Ishii; Hiroki Takemoto; Akio Ojida; Kenta Watanabe; Aya Uemura; Hitoshi Kurose; Takashi Morii; Tsutomu Kobayashi; Yoji Sato; Chikara Sato; Itaru Hamachi; Yasuo Mori

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2009, Peer-reviewed

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• TRPM2チャネルによる活性酸素シグナル増幅と慢性炎症の関連

  山本伸一郎; 清水俊一; 森泰生

  日本薬理学雑誌, 2009

  
• Physiological roles of presynaptic Ca^<2+> channel complexes on neurotransmitter release

  KIYONAKA Shigeki; URIU Yoshitsugu; MIKI Takafumi; MORI Yasuo

  生化学, 25 Jul. 2008

  
• 蛍光性バイオセンサーによるイノシトール四リン酸細胞内動態の計測

  坂口怜子; 清中茂樹; 森泰生; 森井孝

  日本化学会第88春季年会，立教大学池袋キャンパスおよび立教池袋中学校・高等学校，2008.3.26-30, 2008, Peer-reviewed

  
• TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations

  Wen-Li Wei; Hong-Shuo Sun; Michelle E. Olah; Xiujun Sun; Elzbieta Czerwinska; Waldemar Czerwinski; Yasuo Mori; Beverley A. Orser; Zhi-Gang Xiong; Michael F. Jackson; Michael Tymianski; John F. MacDonald

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2007, Peer-reviewed

  
• アンジオテンシンIIで誘発される心肥大の分子機構 : TRPタンパク質を巡って

  西田基宏; 小野原直哉; 井上隆司; 森泰生; 黒瀬等

  日本臨床生理学会雑誌 = Japanese journal of applied physiology, 01 Aug. 2007

  
• Construction of Fluorescent Sensors to Quantitatively Assess Inositol Tetrakisphosphate (IP4) in Single Cell

  R Sakaguchi; K Sugimoto; S Kiyonaka; Y Mori; T Morii

  The 2nd International workshop on Approaches to single-cell Analysis, 早稲田大学，井深大記念館，2007.9.6-7, 2007, Peer-reviewed

  
• 細胞内情報伝達経路の可視化を目指した蛍光分子センサーの開発

  坂口怜子; 杉本健二; 清中茂樹; 森泰生; 森井孝

  第22回生体機能関連化学シンポジウム，東北大学，多元物質科学研究所，2007.9.28-29, 2007, Peer-reviewed

  
• Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum

  Yoshihiro Baba; Kenji Hayashit; Yoko Fujii; Akiko Mizushima; Hiroshi Watarai; Minoru Wakamori; Takuro Numaga; Yasuo Mori; Masamitsu Iino; Masaki Hikida; Tomohiro Kurosaki

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2006, Peer-reviewed

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• A functional AMPA receptor-calcium channel complex in the postsynaptic membrane

  MG Kang; CC Chen; M Wakamori; Y Hara; Y Mori; KP Campbell

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2006, Peer-reviewed

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• Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices

  C Erxleben; YH Liao; S Gentile; D Chin; C Gomez-Alegria; Y Mori; L Birnbaumer; DL Armstrong

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2006, Peer-reviewed

  
• Construction of protein-based optical sensor to quantitatively assess inositol tetrakisphosphate

  R. Sakaguchi; S. Kiyonaka; K. Sugimoto; Y. Mori; T. Morii

  The 3rd International Symposium on Sustainable Energy System，Kyoto University Clock Tower Centennial Hall, Kyoto，2006.8.30-9.1, 2006, Peer-reviewed

  
• AFTERNOON TEA

  森泰生

  日本生理学雜誌 = JOURNAL OF THE PHYSIOLOGICAL SOCIETY OF JAPAN, 01 Dec. 2005

  
• A new high-throughput electrophysiology platform using voltage clamp noise analysis

  YOSHIDA Takashi; KATAYAMA Norihiro; NAKATANI Masaya; KOJIMA Masatoshi; JIKO Hideyasu; MORI Yasuo; TAKETANI Makoto

  Folia Pharmacologica Japonica, 01 Nov. 2005

  
• TRP channels as targets for novel calcium antagonists

  KIYONAKA Shigeki; MORI Yasuo

  Folia Pharmacologica Japonica, 01 Nov. 2005

  
• 3P027 Single particle analysis of non-selective cationpermeable channel TRPC3

  Mio K.; Ogura T.; Hara Y.; Mori Y.; Sato C.

  Seibutsu Butsuri, 19 Oct. 2005

  
• イノシトール四リン酸に対する蛍光性バイオセンサーの構築

  坂口怜子; 杉本健二; 沼賀拓郎; 清中茂樹; 森泰生; 大久保捷敏; 森井孝

  日本化学会第85春季年会，神奈川大学，2005.3.26-29, 2005, Peer-reviewed

  
• Activation of RasGRP3 by phosphorylation of Thr-133 is required ifor B cell receptor-mediated Ras activation

  Y Aiba; M Oh-hora; S Kiyonaka; Y Kimura; A Hijikata; Y Mori; T Kurosaki

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2004, Peer-reviewed

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• TRP Channel Regulated by β-NAD^+ and Its Physiological Functions

  MORI Yasuo; HARA Yuji; ITSUKAICHI Yuko

  VITAMINS, 25 Jul. 2004

  
• 細胞増殖・分化・死を制御するイオンメカニズムと創薬

  森泰生; 稲垣千代子; 久野みゆき; 井上隆司; 岡田泰伸; 今泉祐治

  日本薬理学雑誌, 01 Sep. 2003

  
• 平滑筋受容体作動性Caチャネル分子transient receptor potential(TRP)蛋白質ホモログTRPC6の細胞外および細胞内Ca^<2+>による制御機構(一般演題「イオンチャネル1」)

  史娟; 井上隆司; 森泰生; 伊東祐之

  Journal of smooth muscle research. Japanese section, 27 Apr. 2003

  
• カルシウムチャネルのNADを介した活性制御とその生理的意義(シンポジウム「NADの多様な役割」)

  森泰生

  ビタミン, 25 Apr. 2003

  
• TRPチャネルを中心としたシグナル複合体形成と細胞の増殖・死の制御

  西田基宏; 原雄二; 井上隆司; 森泰生

  日本薬理学雑誌, 01 Apr. 2003

  
• Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop

  C Erxleben; C Gomez-Alegria; T Darden; Y Mori; L Birnbaumer; DL Armstrong

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 2003, Peer-reviewed

  
• 外的環境を感知し生体の恒常性を維持するTRP (Transient Receptor Potential) チャンネル

  原雄二; 森泰生

  ファルマシア, 01 Feb. 2003

  
• 非選択性陽イオンチャネルの微量元素透過と細胞の増殖、生存・死に関する分子生理

  森泰生; 原雄二; 花野豊久

  財団法人ソルト・サイエンス研究財団助成研究報告集, 2003

  
• 脳における多様な非選択的カチオンチャネル (特集 一価チャンネル)

  森泰生; 吉田卓史; 原雄二

  生体の科学, Jul. 2002

  
• Ca〔+〕チャネル TRPチャネル--細胞の恒常性や生存・死を制御するCa〔2+〕透過型カチオンチャネル (〔2002年〕6月第5土曜特集 イオンチャネルの最前線) -- (細胞膜イオンチャネル)

  原雄二; 森泰生

  医学のあゆみ, 29 Jun. 2002

  
• Molecular candidates for capacitative and non-capacitative Ca2+ entry in smooth muscle

  Ryuji Inoue; Yasuo Mori

  Novartis Foundation Symposium, 2002, Peer-reviewed

  
• Evidence in support of a four transmembrane-pore-transmembrane topology model for the Arabidopsis thaliana Na+/K+ translocating AtHKT1 protein, a member of the superfamily of K+ transporters

  Y Kato; M Sakaguchi; Y Mori; K Saito; T Nakamura; EP Bakker; Y Sato; S Goshima; N Uozumi

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2001, Peer-reviewed

  
• 49. 腸間膜微小動脈に存在するnifedipine非感受性高電位活性化, 急速不活性化型Ca^<2+>チャネルの薬理学的特性の検討

  森田浩光; 井上隆司; 森泰生; 伊東祐之

  Journal of smooth muscle research. Japanese section, 27 Apr. 2001

  
• S3-4. 平滑筋受容体作動性Caチャネルの分子実体

  井上隆司; 森泰生; 伊東祐之

  Journal of smooth muscle research. Japanese section, 27 Apr. 2001

  
• Functional disorders of the sympathetic nervous system in mice lacking the alpha(1B) subunit (Ca-v 2.2) of N-type calcium channels

  M Ino; T Yoshinaga; M Wakamori; N Miyamoto; E Takahashi; J Sonoda; T Kagaya; T Oki; T Nagasu; Y Nishizawa; Tanaka, I; K Imoto; S Aizawa; S Koch; A Schwartz; T Niidome; K Sawada; Y Mori

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Apr. 2001, Peer-reviewed

  
• イノシトール三リン酸に対する分子センサーの構築

  杉本健二; 森丼孝; 森泰生; 井本敬二; 大塚雅巳; 牧野圭祐

  第74回日本生化学会大会，4P-114，2001, 2001, Peer-reviewed

  
• 新しい標的分子としてのTRP関連蛋白質--受容体作動性陽イオンチャネルとの分子的相関 (最先端創薬--戦略的アプローチと先端的医薬品) -- (先端的医薬品--単一成分に対するアプローチ)

  井上隆司; 森泰生; 伊東祐之

  蛋白質核酸酵素, Apr. 2000

  
• 生体内セカンドメッセンジャーに対する分子センサーの構築

  杉本健二; 森井孝; 牧野圭祐; 森泰生; 井本敬二; 井上照彦; 杉浦幸雄; 大塚雅巳

  第15回生体機能関連化学シンポジウム，2000, 2000, Peer-reviewed

  
• 受容体活性化されるCa^<2+>流入機構:容量性Ca^<2+>流入とTRPタンパク質

  森泰生; 岡田峯陽; 清水俊一

  日本薬理学雑誌, 01 Sep. 1999

  
• 電位依存性Ca2+チャネルの構造・機能とその異常 (特集 イオンチャネルと疾患--基礎と臨床) -- (基礎 イオンチャネルの分子構造と機能に関する最近の進歩)

  森泰生

  現代医療, Apr. 1999

  
• Mutagenesisによるレセプター,チャネルの構造機能相関解析

  森泰生

  日本生理学雜誌, 01 Oct. 1997

  

Books and Other Publications

• Chapter21 Receptor Signaling Integration by TRP Channelsomes

  Yasuo Mori; Taketoshi Kajimoto; Akito Nakao; Nobuaki Takahashi; Shigeki Kiyonaka, Contributor

  Springer Science 十Business Media B.V., 2011, Not refereed

  

Awards

• 日本薬理学会, 江橋節郎賞

External funds: Kakenhi

• Oxygen biology: a new criterion for integrated understanding of life

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  森 泰生

  From 01 Apr. 2019, To 31 Mar. 2020, Project Closed

  酸素;低酸素環境;活性酸素種;生体イメージング;生体恒常性;イメージング;細胞シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-WRAPUP-19H05448/
• Non-permeation function of TRPM2 channel complexes and its physiological relevance

  Grant-in-Aid for Scientific Research (B)

  Basic Section 48040:Medical biochemistry-related

  Kyoto University

  Yasuo Mori

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  イオンチャネル;TRPチャネル;シグナル伝達;マクロファージ;炎症;カルシウム;活性酸素種;タンパク質間相互作用;免疫応答;TRP;Ca2+;STAT;活性酸素;機能分極;タンパク質複合体;分化;細胞シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03417/
• Elucidation of mechanisms and significance of Ca2+ channel-epigenetics coupling

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yasuo Mori

  From 01 Apr. 2016, To 31 Mar. 2019, Project Closed

  カルシウムチャネル;エピジェネティクス;ヒストン修飾;記憶;転写;副サブユニット;長期記憶;転写調節;てんかん;TRPチャネル;タンパク質複合体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H05140/
• Promotion of oxygen biology on the basis of international networks

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  Yasuo Mori

  From 06 Nov. 2015, To 31 Mar. 2019, Project Closed

  酸素;活性酸素種;細胞シグナル;イメージング;センサー;酸素生物学

  https://kaken.nii.ac.jp/grant/KAKENHI-INTERNATIONAL-15K21759/
• Blockade of TRPC6/3 is a Novel Therapeutic Approach Against Pulmonary Arterial Hypertension

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Hideyuki Kinoshita

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  肺動脈性肺高血圧症;心不全;肺血管リモデリング;受容体活性化型Ca2+チャネル;肺高血圧症

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K09137/
• Oxygen biology: a new criterion for integrated understanding of life

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  From 10 Jul. 2014, To 31 Mar. 2019

  https://kaken.nii.ac.jp/grant/KAKENHI-AREA-3602/
• Lipid regulation on receptor-operated ion channels and its tuning by Ca2+

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Mori Masayuki

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  TRPチャネル;PIP2;G蛋白質受容体;脂質;カルシウムシグナル;平滑筋;Ca2+シグナル;Calmodulin;イノシトール代謝;ＴＲＰチャネル;パッチクランプ;ＦＲＥＴ;ＰＩＰ２;非選択的カチオンチャネル;ＦＳＧＳ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460296/
• Elucidation of epigenetic regulation of gene expresson involved in maintaining cardiac function and metabolism

  Grant-in-Aid for Scientific Research (B)

  Shinshu University;Kyoto University

  Koichiro KUWAHARA

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  分子心臓学;心不全;遺伝子;転写因子;エピゲノム;シグナル伝達経路;転写制御;エピジェネティクス;シグナル経路;循環器;分子心臓病学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293187/
• Roles of ROS-sensitive TRP channels in generation and prolongation of pain and dysesthesia

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Takayuki Nakagawa

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  TRPチャネル;活性酸素種;痛み;しびれ;オキサリプラチン;TRPA1;TRPM2;慢性膀胱炎;薬理学;感覚神経;末梢神経障害;末梢血流障害;疼痛;グリア細胞;抗がん剤誘発末梢神経障害;シュワン細胞;ミクログリア;抗がん剤末梢神経障害

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293019/
• Molecular physiological studies of in vivo hypoxia niche: formation, sensing and adaptation

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  Yasuo Mori

  From 10 Jul. 2014, To 31 Mar. 2019, Project Closed

  酸素;活性酸素種;細胞シグナル;イメージング;低酸素;イオンチャネル;酸素受容;アストロサイト;神経系;ハイポキシア;チャネル;酸素受容器;TRPチャネル;カルシウム;一酸化窒素;生理学;活性酸素

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-26111004/
• Oxygen biology: a new criterion for integrated understanding of life

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  Yasuo Mori

  From 10 Jul. 2014, To 31 Mar. 2019, Project Closed

  酸素;活性酸素種;細胞シグナル;イメージング;酸素生物学;低酸素;生体イメージング;ハイポキシア

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-26111001/
• Establishment of animal models for elucidating the mechanism underlying dysesthesia

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Takayuki NAKAGAWA

  From 01 Apr. 2013, To 31 Mar. 2015, Project Closed

  しびれ;疼痛;動物モデル;感覚神経;TRPA1;オキサリプラチン;虚血再灌流;低酸素;末梢神経障害;末梢血流障害;等津;活性酸素種;虚血/再灌流

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25670285/
• Elucidation of mechanisms underlying regulation of inflammatory cellular responses by redox-sensitive TRP channels.

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Yasuo Mori

  From 01 Apr. 2012, To 31 Mar. 2016, Project Closed

  カルシウム;TRP;チャネル;レドックス;活性酸素種;炎症;生理学;イオンチャネル;シグナル伝達;ストレス;癌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24249017/
• Elucidation of transcriptional and epigenomic regulation in the development of heart failure

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Koichiro KUWAHARA

  From 01 Apr. 2011, To 31 Mar. 2014, Project Closed

  転写調節;心不全;転写;エピゲノム;遺伝子;転写因子;遺伝子発現;イオンチャネル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23390210/
• 活性化学種作動性ＴＲＰチャネル群の感受性定量化の検討

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  森 泰生

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  レドックス;酸素;酸化;還元;活性酸素種;TRPチャネル;カルシウム;活性化学種;シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-23117709/
• PIPs and Ca2+-dependent regulation on Ca channels

  Grant-in-Aid for Young Scientists (A)

  Kyoto University;Fukuoka University

  Mori MASAYUKI

  From 01 Apr. 2010, To 31 Mar. 2014, Project Closed

  生理学;ホスホイノシチド;カルシウム;TRP channel;PIP2;平滑筋;蛍光共鳴エネルギー移動;シミュレーション;イオンチャネル;カルシウムシグナル;蛍光エネルギー移動;TRPCチャネル;電気生理学;平滑筋収縮;血圧調節;TRPチャネル;生理学一般;受容体・イオンチャネル;蛍光エネルギー移動(FRET);カルモジュリン;細胞内カルシウム;生体膜;イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22689006/
• Elucidation of significance of TRPM2 in progression of heart failure

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Yasuaki NAKAGAWA

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  分子心臓病学;分子心臓病態学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590810/
• Functional analysis of oral sensation on the basis of signalplexes

  Grant-in-Aid for Scientific Research (B)

  Tohoku University

  Minoru WAKAMORI

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  パッチクランプ法;TRPM5;TRPV1;チャネル;口腔感覚;カプサイシン受容体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21390494/
• ミトコンドリア活性に伴う細胞内温度変化の計測とその生理学的意義に関する研究

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  森 泰生

  From 01 Apr. 2008, To 31 Mar. 2010, Project Closed

  温度センサー;coiled-coil;蛍光タンパク質;ミトコンドリア;GFP

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20657027/
• Molecular elucidation and medical significance of redox-sensitive TRP channels in inflammatory cell infiltration.

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Yasuo MORI

  From 01 Apr. 2008, To 31 Mar. 2012, Project Closed

  生体分子医学;炎症;チャネル;活性酸素種;酸化ストレス;カルシウム;細胞遊走;生体分子学;細胞死

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20249015/
• Regulation of signals by TRP channels audits physiological significauce

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yasuo MORI

  From 01 Apr. 2006, To 31 Mar. 2008, Project Closed

  シグナル伝達;チャネル;化学遊走;炎症;活性酸素;チャンネル, signal transduction;channel;chemotaxis;inflammation;reactive oxygenspecies

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18390085/
• 優性及び劣性遺伝形態をとる運動失調症マウスの小脳機能の電気生理学的比較

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Tohoku University;Kyoto University

  若森 実

  From 01 Apr. 2006, To 31 Mar. 2008, Project Closed

  チャネル;カルシウム;RIM1;アクティブゾーン;不活性化;運動失調;Cav2.1;βサブユニット;パッチクランプ法;GABA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18019021/
• Transportsome on biomembrane systems: its molecular assembly and physiological function.

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University;Kyorin University

  Yoshikatsu KANAI

  From 01 Apr. 2005, To 31 Mar. 2011, Project Closed

  輸送体;プロスタグランジン;傍糸球体装置;近位尿細管;レニン;膜輸送;トランスポーター;複合体;生体膜;上皮輸送;イオンチャネル;分子複合体;ポンプ;生体恒常性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17081015/
• Ca^<2+> channelplexes : assembly in the membrane and physiological significance

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  Yasuo MORI

  From 01 Apr. 2005, To 31 Mar. 2010, Project Closed

  Ca^<2+>チャネル;分子複合体;膜分子集積;シグナル伝達;バイオセンサー;カルシウムチャネル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17081011/
• 小脳失調症の遺伝子、分子、細胞、小脳回路と多次元コンピュテーショナル神経科学

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University

  若森 実

  From 01 Apr. 2005, To 31 Mar. 2006, Project Closed

  カルシウム;チャネル;パッチクランプ法;運動失調;欠神発作;Loss of Function;Gain of Function;tottering

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17021025/
• in vivoナノ蛋白質工学による神経伝達物質受容体活性化の可視化解析

  Grant-in-Aid for Exploratory Research

  Kyoto University

  森 泰生

  From 01 Apr. 2004, To 31 Mar. 2006, Project Closed

  光アフィニティーラベル化;バイオセンサー;アセチルコリン受容体;プロテオミクス;免疫抑制剤

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16650083/
• Elucidation of physiological significance of direct Ca^<2+> channel-phospholipase coupling in cell fate control

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yasuo MORI

  From 01 Apr. 2004, To 31 Mar. 2006, Project Closed

  細胞運命;カルシウムチャネル;細胞シグナル;受容体;カルシウムシグナル, Cell fate;Calcium channel;Cellular signal;receptor;calcium signal

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390076/
• Mechanism underlying polarized subcellular distribution of Ca channels and its neurobiological significance.

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY;Okazaki National Research Institutes

  Yasuo MORI

  From 01 Apr. 2001, To 31 Mar. 2004, Project Closed

  遺伝子;細胞・組織;生体分子;生理学;薬理学;ノックアウト, receptor activated channel;Ca2+ signal;smooth muscle;endoplasmic reticulum

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14380362/
• 生命1次情報の高速収集とそれに基づく統合バイオサイエンスの展開

  Grant-in-Aid for Creative Scientific Research

  National Institutes of Natural Sciences Okazaki Research Facilities;Okazaki National Research Institutes

  永山 國昭;永山 国昭

  From 01 Apr. 2001, To 31 Mar. 2006, Project Closed

  電子顕微鏡;位相回復法;DNAシーケンサー;チャネル;蛋白質;カルシウム;電位センサー;バイオセンサー;電位依存性蛋白質;DNA;シーケンサー;人口酵素;信号制御;自己組織;人工酵素;自己組織化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13GS0016/
• Molecular physiology of TRP channels induced via activation of metabotropic receptors

  Grant-in-Aid for Scientific Research (C)

  Okazaki National Research Institutes

  Yasuo MORI

  From 01 Apr. 2000, To 31 Mar. 2002, Project Closed

  受容体活性化Ca2+チャネル;Ca2+シグナル;平滑筋;小胞体;形質膜;受容体活性化Ca^<2+>チャネル;Ca^<2+>シグナル, receptor activated channel;Ca2+signal;smooth muscle;endoplasmic reticulum

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670052/
• Molecular physiological characterization of Ca2+ signal-regulating ion channels that control vectorial substance transport

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Kyoto University, Graduate School of Engineering;Okazaki National Research Institutes

  Eyasuo MORI

  From 01 Apr. 2000, To 31 Mar. 2005, Project Closed

  遺伝子;生理学;バイオテクノロジー;薬理学;細胞・組織;イオンチャネル;生体分子;ノックアウトマウス;上皮細胞;Ca^<2+>シグナリング;Ca^<2+>チャネル;小胞体, gene;physiology;biotechnologv;pharmaco logy;cell, tissue;ion channel

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12144210/
• Dynamic analysis of subcellular ionic signalling in neurons

  Grant-in-Aid for Scientific Research (B).

  Okazaki National Research Institutes

  Keiji IMOTO

  From 01 Apr. 1999, To 31 Mar. 2001, Project Closed

  カルシウムチャネル;小脳失調症;変異マウス;TRPチャネル;神経細胞死;グルタミン酸受容体チャネル;ナトリウムチャネル;小脳変性症;ミュータントマウス;脊髄小脳変性症;ポリグルタミン病;非選択性カチオンチャネル;容量性カルシウムチャネル, calcium channel;cerebellar ataxia;mutant mice;TRP channel;neuronal death;glutamate receptor channel;sodium channel

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11694332/
• Characterization of neurological CaィイD12+ィエD1 channel mutant mice.

  Grant-in-Aid for Scientific Research (C)

  National Institute for Physiological Sciences

  Yasuo MORI

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  Ca^<2+>チャネル;ミュータントマウス;運動失調;不活性化;活性化;ポリグルタミン;G蛋白質;神経疾患モデル;遺伝子欠損マウス;変異, CaィイD12+ィエD1;mutant mice;ataxia;inactivation;activation;polyglutamine;G-protein

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10680755/
• Production & analysis of Ca^<2+> channel subunit-defecient mice.

  Grant-in-Aid for international Scientific Research

  National Institute for Physiological Sciences

  Keiji IMOTO

  From 01 Apr. 1997, To 31 Mar. 1999, Project Closed

  カルシウムチャネル;ジーンターゲティング;神経伝導;神経伝達;活動電位, calcium channel;gene targeting;neuronal conduction;neuronal transmission;action potenial

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09044351/
• Studies on molecular mechanism of neural calcium signaling

  Grant-in-Aid for international Scientific Research

  Okazaki National Research Institutes

  Keiji IMOTO

  From 01 Apr. 1996, To 31 Mar. 1997, Project Closed

  カルシウムシグナリング;カルシウムチャネル;GTP結合タンパク;リアノジン受容体;脳スライス;カルシウムイメージング, Calcium signaling;Calcium channel;GTP-binding protein;Ryanodine receptor;Brain slice;Calcium imaging

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08044330/
• Studies on the molecular mechanism for calcium signaling

  Grant-in-Aid for international Scientific Research

  Kyoto University

  Keiji IMOTO

  From 01 Apr. 1993, To 31 Mar. 1994, Project Closed

  カルシウムチャンネル;cDNAクローニング;cDNA発現;部位特異的変異導入;活性化速度;小サブユニット, Calcium channels;cDNA cloning;cDNA expression;Site-specific mutagenesis;Activation kinetics;Small subunits

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05044159/
• 電位依存性カルシウムチャンネルにおけるイオン選択性の構造的基盤に関する研究

  Grant-in-Aid for General Scientific Research (C)

  Kyoto University

  森 泰生

  From 01 Apr. 1992, To 31 Mar. 1993, Project Closed

  カルシウムチャンネル;イオン選択性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04680159/
• Studies on the structural basis for ion channel functions

  Grant-in-Aid for international Scientific Research

  Kyoto University

  Keiji IMOTO

  From 01 Apr. 1992, To 31 Mar. 1993, Project Closed

  イオンチャンネル;cDNAクローニング;cDNA発現;部位特異的変異導入;ニコチン性アセチルコリン受容体;カルシウムチャンネル;ナトリウムチャンネル;リアノジン受容体, Ion channel;cDNA expression;cDNA cloning;Slte-directed mutagenesis;Nicotinic acetycholine receptor;Calcium channel;Sodium channel;Ryanodine receptor

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04044095/
• Elucidating the mechanism and significance of induction of reactive astrocytes via physioxia sensing

  Grant-in-Aid for Scientific Research (B)

  Basic Section 48040:Medical biochemistry-related

  Kyoto University

  森 泰生

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  酸素;低酸素環境;アストロサイト;TRPチャネル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H02816/
• Elucidating the mechanism and significance of induction of reactive astrocytes via physioxia sensing

  Grant-in-Aid for Scientific Research (B)

  Basic Section 48040:Medical biochemistry-related

  Kyoto University

  森 泰生

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  酸素;低酸素環境;アストロサイト;TRPチャネル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K24078/

External funds: others

• Molecular Neurobiology

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Chemistry Scientific English

  7430, Fall, Faculty of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Biochemistry I (Advanced Chemistry)

  7416, Spring, Faculty of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Chemical Basis of Life

  7107, Spring, Faculty of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Biochemistry II

  7064, Fall, Faculty of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Molecular Analysis of Life

  X605, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar C on Integrated Medical Engineering

  X685, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar B on Integrated Medical Engineering

  X684, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar A on Integrated Medical Engineering

  X683, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Special Seminar D on Integrated Medical Engineering

  X686, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Master's Thesis

  X699, Year-long, Graduate School of Engineering, 0
• From 01 Apr. 2024, To 31 Mar. 2025

  Integrated Medical Engineering Seminar A

  X681, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Biological Chemistry 2 Continued

  P836, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Integrated Medical Engineering Seminar B

  X682, Fall, Graduate School of Engineering, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Molecular Biology

  H812, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Biological Chemistry

  H836, Spring, Graduate School of Engineering, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  X672, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  X671, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Chemical Basis of Life

  7107, Spring, Faculty of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Biochemistry II

  7064, Fall, Faculty of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Chemistry Scientific English

  7430, Fall, Faculty of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Biochemistry I (Advanced Chemistry)

  7416, Spring, Faculty of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar D on Integrated Medical Engineering

  X686, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar C on Integrated Medical Engineering

  X685, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar B on Integrated Medical Engineering

  X684, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Special Seminar A on Integrated Medical Engineering

  X683, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Analysis of Life

  X605, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Master's Thesis

  X699, Year-long, Graduate School of Engineering, 0
• From 01 Apr. 2023, To 31 Mar. 2024

  Integrated Medical Engineering Seminar A

  X681, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Biological Chemistry 2 Continued

  P836, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Integrated Medical Engineering Seminar B

  X682, Fall, Graduate School of Engineering, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  H409, Fall, Graduate School of Engineering, 1.5
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Biological Chemistry

  H836, Spring, Graduate School of Engineering, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  X672, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  X671, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Chemistry Scientific English

  7430, Fall, Faculty of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  X672, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  X671, Year-long, Graduate School of Engineering, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Biological Chemistry

  H836, Spring, Graduate School of Engineering, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Biochemistry I (Advanced Chemistry)

  7416, Spring, Faculty of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Seminar D on Integrated Medical Engineering

  X686, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Seminar C on Integrated Medical Engineering

  X685, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Biological Chemistry 2 Continued

  P836, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Biology

  H812, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2022, To 31 Mar. 2023

  Master's Thesis

  X699, Year-long, Graduate School of Engineering, 0
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Analysis of Life

  X605, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Biochemistry II

  7064, Fall, Faculty of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Integrated Medical Engineering Seminar A

  X681, Spring, Graduate School of Engineering, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Seminar A on Integrated Medical Engineering

  X683, Spring, Graduate School of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Integrated Medical Engineering Seminar B

  X682, Fall, Graduate School of Engineering, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Special Seminar B on Integrated Medical Engineering

  X684, Fall, Graduate School of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Chemical Basis of Life(Advanced Chemistry)

  7426, Fall, Faculty of Engineering, 2
• From Apr. 2011, To Mar. 2012

  環境適応生体システム論演習

  Fall, 地球環境学舎
• From Apr. 2011, To Mar. 2012

  環境適応生体システム論

  Spring, 地球環境学舎
• From Apr. 2011, To Mar. 2012

  生化学II

  Fall, 工学部
• From Apr. 2011, To Mar. 2012

  生化学Ｉ（工業基礎化学）

  Spring, 工学部
• From Apr. 2011, To Mar. 2012

  Scientific English

  Fall, 全学共通科目
• From Apr. 2011, To Mar. 2012

  Oxygen: the molecule that made the world

  Spring, 全学共通科目
• From Apr. 2011, To Mar. 2012

  化学から生物へ生物から化学へ

  Fall, 工学研究科
• From Apr. 2011, To Mar. 2012

  生物化学工学

  Fall, 工学部
• From Apr. 2012, To Mar. 2013

  Molecular Biology

  Fall, 工学研究科
• From Apr. 2012, To Mar. 2013

  Environmental systems biology

  Spring, 地球環境学舎
• From Apr. 2012, To Mar. 2013

  Exercise in Environmental systems biology

  Fall, 地球環境学舎
• From Apr. 2012, To Mar. 2013

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2012, To Mar. 2013

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2012, To Mar. 2013

  Biochemical Engineering

  Fall, 工学部
• From Apr. 2012, To Mar. 2013

  Scientific English

  Fall, 全学共通科目
• From Apr. 2012, To Mar. 2013

  Oxygen: the molecule that made the world

  Spring, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2013, To Mar. 2014

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2013, To Mar. 2014

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2013, To Mar. 2014

  Molecular Analysis of Life

  Fall, 医学研究科
• From Apr. 2013, To Mar. 2014

  Synthetic Chemistry and Biological Chemistry, Adv. I

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2013, To Mar. 2014

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2013, To Mar. 2014

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2013, To Mar. 2014

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2013, To Mar. 2014

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2013, To Mar. 2014

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2013, To Mar. 2014

  Environmental systems biology

  Spring, 地球環境学舎
• From Apr. 2013, To Mar. 2014

  Exercise in Environmental systems biology

  Fall, 地球環境学舎
• From Apr. 2013, To Mar. 2014

  Scientific English

  Fall, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Oxygen: the molecule that made the world

  Spring, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2014, To Mar. 2015

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2014, To Mar. 2015

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2014, To Mar. 2015

  Molecular Analysis of Life

  Fall, 医学研究科
• From Apr. 2014, To Mar. 2015

  Molecular Biology

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2014, To Mar. 2015

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2014, To Mar. 2015

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2014, To Mar. 2015

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2014, To Mar. 2015

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2014, To Mar. 2015

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2014, To Mar. 2015

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2014, To Mar. 2015

  Global Environmental Engineering

  Spring, 地球環境学舎
• From Apr. 2014, To Mar. 2015

  Environmental systems biology

  Spring, 地球環境学舎
• From Apr. 2014, To Mar. 2015

  Exercise in Environmental systems biology

  Fall, 地球環境学舎
• From Apr. 2014, To Mar. 2015

  Scientific English

  Fall, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Global Environmental Engineering

  Spring, 地球環境学舎
• From Apr. 2015, To Mar. 2016

  Environmental systems biology

  Spring, 地球環境学舎
• From Apr. 2015, To Mar. 2016

  Exercise in Environmental systems biology

  Fall, 地球環境学舎
• From Apr. 2015, To Mar. 2016

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2015, To Mar. 2016

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2015, To Mar. 2016

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2015, To Mar. 2016

  Molecular Analysis of Life

  Fall, 医学研究科
• From Apr. 2015, To Mar. 2016

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Frontiers of Biology

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Diagnostic Pathology: practice

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Diagnostic Pathology : lecture

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2015, To Mar. 2016

  Scientific English

  Fall, 工学部
• From Apr. 2015, To Mar. 2016

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2015, To Mar. 2016

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2015, To Mar. 2016

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Biology

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Exercise in Environmental systems biology

  Fall, 地球環境学舎
• From Apr. 2016, To Mar. 2017

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2016, To Mar. 2017

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2016, To Mar. 2017

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2016, To Mar. 2017

  Molecular Analysis of Life

  Fall, 医学研究科
• From Apr. 2016, To Mar. 2017

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Frontiers of Biology

  Spring, 全学共通科目
• From Apr. 2016, To Mar. 2017

  Diagnostic Pathology: practice

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Diagnostic Pathology : lecture

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2016, To Mar. 2017

  Scientific English

  Fall, 工学部
• From Apr. 2016, To Mar. 2017

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2016, To Mar. 2017

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2016, To Mar. 2017

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry III

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry II

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry IV

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry I

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry VI

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Seminar on Materials Engineering and Chemistry V

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory and Exercise on Materials Engineering and Chemistry III

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory and Exercise on Materials Engineering and Chemistry II

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory and Exercise on Materials Engineering and Chemistry IV

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory and Exercise on Materials Engineering and Chemistry I

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2017, To Mar. 2018

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2017, To Mar. 2018

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2017, To Mar. 2018

  Molecular Analysis of Life (LIMS)

  Fall, 医学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Diagnostic Pathology: practice

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Diagnostic Pathology : lecture

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2017, To Mar. 2018

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2017, To Mar. 2018

  Scientific English

  Fall, 工学部
• From Apr. 2017, To Mar. 2018

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2017, To Mar. 2018

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2017, To Mar. 2018

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Biology

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar 1 in Synthetic Chemistry and Biological Chemistry

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar 2 in Synthetic Chemistry and Biological Chemistry

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar 3 in Synthetic Chemistry and Biological Chemistry

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Experiments and Exercises Synthetic Chemistry and Biological Chemistry

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Synthetic Chemistry and Biological Chemistry, Adv,B

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Synthetic Chemistry and Biological Chemistry, Adv,D

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Synthetic Chemistry and Biological Chemistry, Adv,F

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry III

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry II

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry IV

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry I

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry VI

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Seminar on Materials Engineering and Chemistry V

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory and Exercise on Materials Engineering and Chemistry III

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory and Exercise on Materials Engineering and Chemistry II

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory and Exercise on Materials Engineering and Chemistry IV

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory and Exercise on Materials Engineering and Chemistry I

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2018, To Mar. 2019

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2018, To Mar. 2019

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2018, To Mar. 2019

  Molecular Analysis of Life (LIMS)

  Fall, 医学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Scientific English

  Fall, 工学部
• From Apr. 2018, To Mar. 2019

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2018, To Mar. 2019

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2018, To Mar. 2019

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  Fall, 工学研究科
• From Apr. 2019, To Mar. 2020

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2019, To Mar. 2020

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2019, To Mar. 2020

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2019, To Mar. 2020

  Molecular Analysis of Life (LIMS)

  Fall, 医学研究科
• From Apr. 2019, To Mar. 2020

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2019, To Mar. 2020

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2019, To Mar. 2020

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2019, To Mar. 2020

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2019, To Mar. 2020

  Scientific English

  Fall, 工学部
• From Apr. 2019, To Mar. 2020

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2019, To Mar. 2020

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2019, To Mar. 2020

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2019, To Mar. 2020

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2019, To Mar. 2020

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Biology

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2020, To Mar. 2021

  Basic Biochemistry I (Fundamental Chemistry)

  Spring, 工学部
• From Apr. 2020, To Mar. 2021

  Chemical Basis of Life(Fundamental Chemistry)

  Fall, 工学部
• From Apr. 2020, To Mar. 2021

  Molecular Analysis of Life (LIMS)

  Fall, 医学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2020, To Mar. 2021

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2020, To Mar. 2021

  Scientific English

  Fall, 工学部
• From Apr. 2020, To Mar. 2021

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2020, To Mar. 2021

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2020, To Mar. 2021

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2020, To Mar. 2021

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2020, To Mar. 2021

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Biological Chemistry

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Biological Chemistry 2 Continued

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  Fall, 工学研究科
• From Apr. 2021, To Mar. 2022

  Introduction to Industrial Chemistry

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Introduction to Industrial Chemistry

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Introduction to Industrial Chemistry

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Introduction to Industrial Chemistry

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Basic Biochemistry II

  Fall, 工学部
• From Apr. 2021, To Mar. 2022

  Basic Biochemistry I (Advanced Chemistry)

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Chemical Basis of Life(Advanced Chemistry)

  Fall, 工学部
• From Apr. 2021, To Mar. 2022

  Molecular Analysis of Life (LIMS)

  Fall, 医学研究科
• From Apr. 2021, To Mar. 2022

  Molecular Analysis of Life

  Fall, 工学研究科
• From Apr. 2021, To Mar. 2022

  Master's Thesis

  Year-long, 工学研究科
• From Apr. 2021, To Mar. 2022

  Scientific English

  Fall, 工学部
• From Apr. 2021, To Mar. 2022

  Integrated Medical Engineering Seminar A

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Integrated Medical Engineering Seminar B

  Fall, 工学研究科
• From Apr. 2021, To Mar. 2022

  Special Seminar A on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Special Seminar B on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2021, To Mar. 2022

  Special Seminar C on Integrated Medical Engineering

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Special Seminar D on Integrated Medical Engineering

  Fall, 工学研究科
• From Apr. 2021, To Mar. 2022

  Experiments and Exercises on Integrated Medical Engineering, Adv. I

  Year-long, 工学研究科
• From Apr. 2021, To Mar. 2022

  Experiments and Exercises on Integrated Medical Engineering, Adv. II

  Year-long, 工学研究科