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Shimokawa, Jun

Graduate School of Science, Division of Chemistry Associate Professor

Shimokawa, Jun
list
    Last Updated :2024/09/18

    Basic Information

    Faculty

    • 理学部

    Professional Memberships

    • American Chemical Society
    • THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
    • THE CHEMICAL SOCIETY OF JAPAN
    • THE PHARMACEUTICAL SOCIETY OF JAPAN

    Academic Degree

    • 修士(薬学)(東京大学)
    • 博士(薬学)(東京大学)

    Research History

    • From Jan. 2018, To Present
      Kyoto University, Graduare School of Science, Associate Professor
    • From Apr. 2012, To Dec. 2017
      Nagoya University, Graduate School of Pharmaceutical Sciences, Assistant Professor
    • From Apr. 2006, To Mar. 2012
      The University of Tokyo, Graduate School of Pharmaceutical Sciences, 助教

    Language of Instruction

    • English

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2024/09/18

      Research

      Research Interests

      • silicon
      • silicon chemistry
      • 全合成
      • アルカロイド
      • 天然物
      • 天然物全合成
      • 天然物合成
      • 合成化学
      • 生理活性物質
      • 医薬品
      • 有機合成化学

      Research Areas

      • Life sciences, Bioorganic chemistry
      • Nanotechnology/Materials, Structural/physical organic chemistry
      • Nanotechnology/Materials, Synthetic organic chemistry
      • Life sciences, Pharmaceuticals - chemistry and drug development

      Papers

      • Modified mcfadyen-stevens reaction for a versatile synthesis of aromatic aldehydes
        Yuri Iwai; Jun Shimokawa
        Organic Syntheses, 2018
      • Utilization of Silanols in Transition Metal-Catalyzed Organic Synthesis
        Hiroki Yamagishi; Jun Shimokawa; Hideki Yorimitsu
        ACS Catalysis, 02 Jun. 2023
      • Regioselective anti-Silyllithiation of Propargylic Amines
        Jun Shimokawa; Hideki Yorimitsu; Tomohiko Sato; Somnath N. Karad
        Synlett, 12 Apr. 2023
      • Diphenylsilylsilanolates Enable the Transfer of a Wide Range of Silyl Groups
        Hiroki Yamagishi; Fuyuki Harata; Jun Shimokawa; Hideki Yorimitsu
        Organic Letters, 13 Jan. 2023
      • Regioselective Anti-Silyllithiation of Propargylic Alcohols
        Somnath N. Karad; Hayate Saito; Jun Shimokawa; Hideki Yorimitsu
        The Journal of Organic Chemistry, 07 Nov. 2022
      • P-431 Synthetic Studies on (-)-Gelsemoxonine
        Shimokawa Jun; Yokoshima Satoshi; Fukuyama Tohru
        International Symposium on the Chemistry of Natural Products, 23 Jul. 2006
      • 8(B-4) Total Synthesis of Batzelladines and Mechanistic Studies toward the Elucidation of Their Biological Activity
        Shimokawa Jun; Hashimoto Yuichi; Nagasawa Kazuo
        Symposium on the Chemistry of Natural Products, symposium papers, 01 Oct. 2004
      • Sodium silylsilanolate as a precursor of silylcopper species.
        Hiroki Yamagishi; Kenshiro Hitoshio; Jun Shimokawa; Hideki Yorimitsu
        Chemical Science, 13 Apr. 2022, Peer-reviewed, Corresponding author
      • AgF‐Mediated Electrophilic Amination of Alkoxyarylsilanes with Azodicarboxylates
        Qian Zhang; Shijun Deng; Dong Li; Jun Shimokawa; Hideki Yorimitsu
        Chemistry – An Asian Journal, 22 Jan. 2022, Peer-reviewed, Corresponding author
      • Design, Synthesis, and Implementation of Sodium Silylsilanolates as Silyl Transfer Reagents
        Hiroki Yamagishi; Hayate Saito; Jun Shimokawa; Hideki Yorimitsu
        ACS Catalysis, 20 Aug. 2021, Peer-reviewed, Corresponding author
      • Sodium silylsilanolate enables nickel-catalysed silylation of aryl chlorides
        Kenshiro Hitoshio; Hiroki Yamagishi; Jun Shimokawa; Hideki Yorimitsu
        Chemical Communications, 2021, Peer-reviewed, Corresponding author
      • Dioxasilepanyl Group as a Versatile Organometallic Unit: Studies in Stability, Reactivity, and Utility
        Hayate Saito; Jun Shimokawa; Hideki Yorimitsu
        Chemical Science, 2021, Peer-reviewed, Corresponding author
      • Palladium-Catalyzed Silylation of Aryl Chlorides with Bulky Dialkoxydisilanes
        Keitaro Fukui; Hayate Saito; Jun Shimokawa; Hideki Yorimitsu
        Synlett, 02 Aug. 2020, Peer-reviewed, Corresponding author
      • Copper-Catalyzed Electrophilic Amination of Alkoxyarylsilanes
        Qian Zhang; Kenshiro Hitoshio; Hayate Saito; Jun Shimokawa; Hideki Yorimitsu
        European Journal of Organic Chemistry, 15 Jul. 2020, Peer-reviewed, Corresponding author
      • C−F Arylation of Polyfluorophenols by Means of Sigmatropic Dearomatization/Defluorination Sequence
        Koichi Okamoto; Keisuke Nogi; Jun Shimokawa; Hideki Yorimitsu
        Chemistry – A European Journal, 04 May 2020, Peer-reviewed
      • Copper-Catalyzed Twofold Silylmetalation of Alkynes
        Hiroki Yamagishi; Jun Shimokawa; Hideki Yorimitsu
        Synlett, Aug. 2019, Peer-reviewed, Corresponding author
      • Photoredox Fischer Indole Synthesis
        Atsushi Kaga; Tomohiro Fukushima; Jun Shimokawa; Masato Kitamura
        Synthesis (Germany), 2019, Peer-reviewed
      • Identification of Target Protein for Batzelladines as CD4
        Jun Shimokawa; Kazuo Nagasawa
        Heterocycles, Dec. 2018, Peer-reviewed
      • Four-component Coupling Strategy for 2,3,4-Trisubstituted 3,4-Dihydroquinoline
        Hiroki Yamagishi; Shun Tsuchiya; Hayate Saito; Keisuke Nogi; Jun Shimokawa; Hideki Yorimitsu
        Heterocycles, Oct. 2018, Peer-reviewed
      • Synthesis of the core structure of phalarine
        Kazuya Douki; Jun Shimokawa; Masato Kitamura
        Organic & Biomolecular Chemistry, Oct. 2018, Peer-reviewed
      • Synthetic Studies on Heteropolycyclic Natural Products: Development of Divergent Strategy
        Shimokawa Jun
        CHEMICAL & PHARMACEUTICAL BULLETIN, Feb. 2018, Peer-reviewed
      • Natural product synthesis as a source of inspiration and discovery
        Jun Shimokawa
        Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2018, Peer-reviewed
      • The cryo-EM structure of gastric H+, K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors
        Kazuhiro Abe; Jun Shimokawa; Mao Naito; Keith Munson; Olga Vagin; George Sachs; Hiroshi Suzuki; Kazutoshi Tani; Yoshinori Fujiyoshi
        SCIENTIFIC REPORTS, Jul. 2017, Peer-reviewed
      • Synthetic studies on heteropolycyclic natural products: Strategies via novel reactions and reactivities
        Jun Shimokawa; Tohru Fukuyama
        Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2017, Peer-reviewed
      • Enantioselective Total Synthesis of (+)-Hinckdentine A via a Catalytic Dearomatization Approach
        Kazuya Douki; Hiroyuki Ono; Tohru Taniguchi; Jun Shimokawa; Masato Kitamura; Tohru Fukuyama
        JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Nov. 2016, Peer-reviewed
      • Unified Total Synthesis of Five Gelsedine-Type Alkaloids: (-)-Gelsenicine, (-)-Gelsedine, (-)-Gelsedilam, (-)-14-Hydroxygelsenicine, and (-)-14,15-Dihydroxygelsenicine
        Takaaki Harada; Jun Shirnokawa; Tohru Fukuyama
        ORGANIC LETTERS, Sep. 2016, Peer-reviewed
      • Development of a Divergent Synthetic Route to the Erythrina Alkaloids: Asymmetric Syntheses of 8-Oxo-erythrinine, Crystamidine, 8-Oxo-erythraline, and Erythraline
        Hirotatsu Umihara; Tomomi Yoshino; Jun Shimokawa; Masato Kitamura; Tohru Fukuyama
        ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Jun. 2016, Peer-reviewed
      • Antiproliferative activity of amathaspiramide alkaloids and analogs
        Jun Shimokawa; Koji Chiyoda; Hirotatsu Umihara; Tohru Fukuyama
        Chemical and Pharmaceutical Bulletin, 2016, Peer-reviewed
      • Synthesis of the Common Core Structure of the Stemofoline Alkaloids
        Eiji Ideue; Jun Shimokawa; Tohru Fukuyama
        ORGANIC LETTERS, Oct. 2015, Peer-reviewed
      • Divergent strategy in natural product total synthesis
        Jun Shimokawa
        TETRAHEDRON LETTERS, Nov. 2014, Peer-reviewed
      • Erratum: Total synthesis of tryprostatins A and B (Angewandte Chemie - International Edition (2010) (49))
        Takayuki Yamakawa; Eiji Ideue; Jun Shimokawa; Tohru Fukuyama
        Angewandte Chemie International Edition, Aug. 2014, Peer-reviewed
      • Stereoselective synthesis of spirotryprostatin A
        Katsushi Kitahara; Jun Shimokawa; Tohru Fukuyama
        CHEMICAL SCIENCE, Mar. 2014, Peer-reviewed
      • TMSCN/DBU-Mediated Facile Redox Transformation of alpha,beta-Unsaturated Aldehydes to Carboxylic Acid Derivatives
        Hiromi Kaise; Jun Shimokawa; Tohni Fukuyama
        ORGANIC LETTERS, Feb. 2014, Peer-reviewed
      • Development of a route to chiral epidithiodioxopiperazine moieties and application to the asymmetric synthesis of (+)-hyalodendrin
        Ren Takeuchi; Jun Shimokawa; Tohru Fukuyama
        CHEMICAL SCIENCE, 2014, Peer-reviewed
      • Modified McFadyen-Stevens reaction for a versatile synthesis of aliphatic/aromatic aldehydes: design, optimization, and mechanistic investigations
        Yuri Iwai; Takashi Ozaki; Ryo Takita; Masanobu Uchiyama; Jun Shimokawa; Tohru Fukuyama
        CHEMICAL SCIENCE, 2013, Peer-reviewed
      • Convenient synthesis of α-diazoacetates from α-bromoacetates and n,n'-ditosylhydrazine: Preparation of benzyl diazoacetate
        Eiji Ideue; Tatsuya Toma; Jun Shimokawa; Tohru Fukuyama
        Organic Syntheses, 2012, Peer-reviewed
      • Total synthesis of gelsemoxonine
        Jun Shimokawa; Takaaki Harada; Satoshi Yokoshima; Tohru Fukuyama
        PURE AND APPLIED CHEMISTRY, 2012, Peer-reviewed
      • Efficient synthesis of oxime using o-tbs-n-tosylhydroxylamine: Preparation of (2z)-4-(benzyloxy)but-2-enal oxime
        Katsushi Kitahara; Tatsuya Toma; Jun Shimokawa; Tohru Fukuyama
        Organic Syntheses, 2012, Peer-reviewed
      • Total Syntheses of All the Amathaspiramides
        Koji Chiyoda; Jun Shimokawa; Tohru Fukuyama
        ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, Peer-reviewed
      • Total synthesis of gelsemoxonine
        Jun Shimokawa; Takaaki Harada; Satoshi Yokoshima; Tohru Fukuyama
        PURE AND APPLIED CHEMISTRY, 2012, Peer-reviewed
      • Total Synthesis of Gelsemoxonine
        Jun Shimokawa; Takaaki Harada; Satoshi Yokoshima; Tohru Fukuyama
        JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Nov. 2011, Peer-reviewed
      • CONFIRMATION OF MOLECULAR PLANARITY DISRUPTION.. EFFECT ON AQUEOUS SOLUBILITY IMPROVEMENT OF beta-NAPHTHOFLAVONE ANALOGS
        Yuji Fujita; Mitsuhiro Yonehara; Katsushi Kitahara; Jun Shimokawa; Yuichi Hashimoto; Minoru Ishikawa
        HETEROCYCLES, Nov. 2011, Peer-reviewed
      • Total Synthesis of Gelsemoxonine
        Jun Shimokawa; Takaaki Harada; Satoshi Yokoshima; Tohru Fukuyama
        JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Nov. 2011, Peer-reviewed
      • CONFIRMATION OF MOLECULAR PLANARITY DISRUPTION.. EFFECT ON AQUEOUS SOLUBILITY IMPROVEMENT OF beta-NAPHTHOFLAVONE ANALOGS
        Yuji Fujita; Mitsuhiro Yonehara; Katsushi Kitahara; Jun Shimokawa; Yuichi Hashimoto; Minoru Ishikawa
        HETEROCYCLES, Nov. 2011, Peer-reviewed
      • 21 Total Synthesis of Gelsemoxonine(Oral Presentation)
        Shimokawa J.; Harada T.; Yokoshima S.; Fukuyama T.
        Symposium on the Chemistry of Natural Products, symposium papers, 02 Sep. 2011
      • Total synthesis of tryprostatins A and B
        Takayuki Yamakawa; Eiji Ideue; Yuzo Iwaki; Ayumu Sato; Hidetoshi Tokuyama; Jun Shimokawa; Tohru Fukuyama
        TETRAHEDRON, Sep. 2011, Peer-reviewed
      • Total Synthesis of Tryprostatins A and B
        Takayuki Yamakawa; Eiji Ideue; Jun Shimokawa; Tohru Fukuyama
        ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, Peer-reviewed
      • O-TBS-N-tosylhydroxylamine: A reagent for facile conversion of alcohols to oximes
        Katsushi Kitahara; Tatsuya Toma; Jun Shimokawa; Tohru Fukuyama
        ORGANIC LETTERS, Jun. 2008, Peer-reviewed
      • N,N′-ditosylhydrazine: A convenient reagent for facile synthesis of diazoacetates
        Tatsuya Toma; Jun Shimokawa; Tohru Fukuyama
        Organic Letters, 02 Aug. 2007, Peer-reviewed
      • Synthesis and Biological Activities on Batzelladine Derivatives
        Jun Shimokawa; Yumi Iijima; Yuichi Hashimoto; Harumi Chiba; Haruo Tanaka; Kazuo Nagasawa
        HETEROCYCLES, 12 Jan. 2007, Peer-reviewed
      • Synthetic studies on cyclic guanidine natural products for the elucidation of their controlling mechanism of protein-protein interaction
        Kazuo Nagasawa; Jun Shimokawa
        Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2006, Peer-reviewed
      • Total synthesis of (+)-batzelladine A and (-)-batzelladine D, and identification of their target protein
        J Shimokawa; T Ishiwata; K Shirai; H Koshino; A Tanatani; T Nakata; Y Hashimoto; K Nagasawa
        CHEMISTRY-A EUROPEAN JOURNAL, Nov. 2005, Peer-reviewed
      • Enantioselective total synthesis of batzelladine A
        J Shimokawa; K Shirai; A Tanatani; Y Hashimoto; K Nagasawa
        ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, Peer-reviewed

      Misc.

      • Synthesis of Unsymmetric Silanediols from Tetraalkoxysilanes Having Seven-Membered Ring Structure
        寺西建登; 一入賢之朗; 前田紘希; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2023
      • カリウムtert-ブトキシドとジシランを用いる有機ハロゲン化物のジオキサシレパニル化
        下川淳; 一入賢之朗; 齊藤颯; 依光英樹
        次世代を担う有機化学シンポジウム講演要旨集, 2023
      • Silylation of Aryl Bromides with Tetraalkoxydisilane Bearing 7-Membered Skeletons
        一入賢之朗; 齊藤颯; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2022
      • Synthesis of Silylsilanolates with New Substitution Patterns
        原田布由樹; 山岸拓幹; 一入賢之朗; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2022
      • Sequential Nucleophilic Substitution Reactions of Organometallic Reagents to 7-Membered Tetraalkoxysilanes
        前田紘希; 一入賢之朗; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2022
      • Potassium tert-Butoxide-Mediated Silylation of Organic Halides with a Disilane Having Seven-Membered Dialkoxysilyl Groups
        一入賢之朗; 齊藤颯; 下川淳; 依光英樹
        有機典型元素化学討論会講演要旨集, 2022
      • Nickel-Catalyzed Silylation of Aryl Chlorides with Silylsilanolates
        一入賢之朗; 山岸拓幹; 下川淳; 依光英樹
        有機典型元素化学討論会講演要旨集, 2021
      • Synthesis and biological activities on batzelladine derivatives
        Jun Shimokawa; Yumi Iijima; Yuichi Hashimoto; Harumi Chiba; Haruo Tanaka; Kazuo Nagasawa
        HETEROCYCLES, Apr. 2007
      • Development of Silylsilanolates as New Silylating Reagents for Silylation of Complex Molecules
        山岸拓幹; 齊藤颯; 下川淳; 依光英樹
        複素環化学討論会講演要旨集, 2021
      • Nickel-Catalyzed Silylation of Aryl Chlorides with Silylsilanolates
        一入賢之朗; 山岸拓幹; 下川淳; 依光英樹
        複素環化学討論会講演要旨集, 2021
      • Development of 7-Membered Alkoxysilyl Group and its Implementation to Organic Synthesis
        下川淳; 齊藤颯; 佐橋遼平; 依光英樹
        複素環化学討論会講演要旨集, 2021
      • Development of 7-membered Trialkoxysilyl Group and its Application
        佐橋遼平; 齊藤颯; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2021
      • Nickel-catalyzed Silylation of Aryl Chlorides with New Silylating Reagents Silylsilanolates
        一入賢之朗; 山岸拓幹; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(Web), 2021
      • Development of disilanolate as a new silylating reagent
        山岸拓幹; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 2020
      • Development of 7-Membered Dialkoxysilyl Group and its Application
        齊藤颯; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 2020
      • Regioselective Addition of Silyllithium to Propargyl Amines
        佐藤友彦; KARAD Somnath; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 2020
      • 7員環構造を有するジアルコキシシリル基の開発と利用
        齊藤颯; 下川淳; 依光英樹
        次世代を担う有機化学シンポジウム講演要旨集, 2020
      • アルコキシジシランを用いたパラジウム触媒による芳香族C‐H結合のシリル化
        福永大喜; 山岸拓幹; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 01 Mar. 2019
      • アルキンに対するアルコキシシリル銅種の付加
        山岸拓幹; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 01 Mar. 2019
      • 嵩高いアルコキシ基を有するジシランを用いたハロゲン化アリールの触媒的シリル化
        福井啓太郎; 齊藤颯; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 01 Mar. 2019
      • 安定性と反応性の両立を指向したアルコキシシリル基の開発
        齊藤颯; 下川淳; 依光英樹
        日本化学会春季年会講演予稿集(CD-ROM), 01 Mar. 2019
      • 安定性と反応性の両立を指向したアルコキシシリル基の開発
        齊藤颯; 下川淳; 依光英樹
        有機典型元素化学討論会講演要旨集, 2019
      • 2,3,4位3置換3,4‐ジヒドロキノリン合成を目的とした4成分カップリング
        山岸拓幹; 土屋駿; 齊藤颯; 野木馨介; 下川淳; 依光英樹
        有機典型元素化学討論会講演要旨集, 13 Dec. 2018
      • 縮環型アルカロイド-ミンフィエンシンの短工程不斉全合成
        下川 淳
        ファルマシア, 01 Mar. 2010
      • バゼラジン類の全合成
        長澤和夫; 下川淳; 飯島有美
        天然物化学-海産天然物編, 2008

      Awards

      • 17 Apr. 2018
        Minister of Education, Culture, Sports, Science and Technology, The Young Scientists’ Prize, The Commendation for Science and Technology
      • 09 Dec. 2017
        MSD Life Science Foundation, Chemist Award BCA 2017
      • 24 Mar. 2017
        The Pharmaceutical Society of Japan, The Pharmaceutical Society of Japan Award for Young Scientists
      • 30 Oct. 2016
        Advanced Research Network for Asian Cutting-Edge Organic Chemistry, Asian Core Program / Advanced Research Network Lectureship Award (China)
      • 30 Oct. 2016
        Advanced Research Network for Asian Cutting-Edge Organic Chemistry, Asian Core Program / Advanced Research Network Lectureship Award (China)
      • 19 Feb. 2015
        The Society of Synthetic Organic Chemistry, Japan, Mitsubishi Tanabe Pharma Corporation Award in Synthetic Organic Chemistry, Japan
      • 02 Dec. 2014
        Georg Thieme Verlag Stuttgardt, New York, Thieme Chemistry Journals Award 2014
      • 07 Jul. 2012
        天然物化学談話会, Young Scientist’s Research Award in Natural Product Chemistry

      External funds: Kakenhi

      • Innovation in reactions and synthesis of silanols
        Grant-in-Aid for Scientific Research (B)
        Basic Section 33020:Synthetic organic chemistry-related
        Kyoto University
        下川 淳
        From 01 Apr. 2021, To 31 Mar. 2025, Granted
        シラノール;ケイ素化医薬;シランジオール;シリルシラノラート;ケイ素;有機合成化学;シリル化
      • Studies on the Comprehensive Syntheses of Erythrina Alkaloids for Medical Research of Central Nervous System
        Grant-in-Aid for Young Scientists (A)
        Kyoto University;Nagoya University
        Jun Shimokawa
        From 01 Apr. 2015, To 31 Mar. 2018, Project Closed
        エリスリナアルカロイド;天然物全合成;ニコチン性アセチルコリン受容体;多分化能性合成中間体;全合成;一重項酸素;天然物合成化学;多様性志向型合成;天然物合成;光反応;多様性指向型合成
      • 希少化合物の供給および有用化合物の構造改変を指向した生体機能分子の合成研究
        Grant-in-Aid for Scientific Research (A)
        Nagoya University
        福山 透
        From 01 Apr. 2013, To 31 Mar. 2018, Adopted
        天然物;アルカロイド;全合成;希少化合物;量的供給
      • Synthetic Studies toward Large-scale production and Optimal Modification of Biologically Significant, Scarce Molecules
        Grant-in-Aid for Scientific Research (S)
        Nagoya University
        Tohru Fukuyama
        From 31 May 2013, To 31 Mar. 2018, Project Closed
        全合成;生体機能分子;量的供給;構造会へ念;天然有機化合物;構造改変
      • Synthetic Studies of Polycyclic Natural Product Stemofoline and Its SAR Study
        Grant-in-Aid for Scientific Research (C)
        Nagoya University;The University of Tokyo
        Jun SHIMOKAWA
        From 01 Apr. 2011, To 31 Mar. 2014, Project Closed
        合成化学;天然物全合成;アルツハイマー病;ステモフォリン;天然物合成化学;全合成;アセチルコリン分解酵素阻害薬
      • Synthetic Studies on Tryprostatins for the Development of Versatile Analogs
        Grant-in-Aid for Young Scientists (B)
        The University of Tokyo
        Jun SHIMOKAWA
        From 01 Apr. 2009, To 31 Mar. 2011, Project Closed
        合成化学;生理活性物質の全合成;ラジカル反応;トリプロスタチン;天然物全合成;天然物合成
      • 斬新かつ実用性を追求した生体機能分子の合成研究
        Grant-in-Aid for Scientific Research (S)
        The University of Tokyo
        福山 透
        From 01 Apr. 2008, To 31 Mar. 2009, Project Closed
        全合成;アルカロイド;希少天然物;実用的合
      • Synthetic Studies on Biologically Functional Molecules
        Grant-in-Aid for Specially Promoted Research
        Science and Engineering
        Nagoya University;The University of Tokyo
        Tohru FUKUYAMA
        From 01 Apr. 2008, To 31 Mar. 2013, Project Closed
        アルカロイド;全合成;医薬品;実用的合成;生体機能分子;天然有機化合物;有機合成化学
      • ゲルセモキソニンの合成研究
        Grant-in-Aid for Young Scientists (Start-up)
        The University of Tokyo
        下川 淳
        From 01 Apr. 2006, To 31 Mar. 2008, Project Closed
        天然物;全合成;アルカロイド;ゲルセミウム属アルカロイド;アゼチジン環;オキシンドール;スピロ化合物
      • 強力な抗ガン機能を有する生体機能分子の独創的合成ルートの開発
        Grant-in-Aid for Scientific Research on Priority Areas
        Science and Engineering
        The University of Tokyo
        福山 透
        From 01 Apr. 2004, To 31 Mar. 2008, Project Closed
        ガン;抗癌薬;天然物;全合成;ビンブラスチン;エクチナサイジン;マンザミン;類縁体;誘導体;含窒素化合物;アルカロイド;抗ガン機能;生体機能分子;イソキノリン;インドール;抗ガン剤;エクチナサイジン743;Ugi反応;短工程化;高活性
      • Development of novel synthetic routes toward natural products including heteroatoms
        Grant-in-Aid for Scientific Research (S)
        The University of Tokyo
        Tohru FUKUYAMA
        From 01 Apr. 2003, To 31 Mar. 2008, Project Closed
        天然物全合成;有機合成化学;アルカロイド;タミフル;生理活性物質;全合成;リード化合物;含窒素化合物;ヤタケマイシン;コノフィリン;モルヒネ;リゼルグ酸;オセルタミビル;天然物;ヘテロ元素;CH挿入反応;環化反応;高次構造;ストリキニーネ;インドール;中大員環構築;FR901483;カゴ型骨格;ナフチリジノマイシン;Ugi4成分連結反応;芳香族アミノ化反応;デュオカルマイシン;ロイストロダクシン;ジヒドロベンゾフラン;エフェドラジン;ニトロベンゼンスルホニル基, Total Synthesis;Organic Chemistry;Alkaloids;Tamiflu;Biologically Active Compounds
      • Innovation in reactions and synthesis of silanols
        Grant-in-Aid for Scientific Research (B)
        Basic Section 33020:Synthetic organic chemistry-related
        Kyoto University
        下川 淳
        From 01 Apr. 2021, To 31 Mar. 2025, Granted
        シラノール;ケイ素化医薬;シランジオール;シリルシラノラート;ケイ素;有機合成化学;シリル化
      list
        Last Updated :2024/09/18

        Education

        Teaching subject(s)

        • From 01 Apr. 2024, To 31 Mar. 2025
          Basic Organic Chemistry I
          N347, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Fundamental Chemical Experiments
          N308, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Seminar on Organic Chemistry IIB
          7081, Fall, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Seminar on Organic Chemistry IIA
          7080, Spring, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Advanced Organic Chemistry IIA
          7184, Spring, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Seminar on Organic Chemistry IID
          7083, Fall, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Seminar on Organic Chemistry IIC
          7082, Spring, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Advanced Organic Chemistry IID
          7187, Fall, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Advanced Organic Chemistry IIC
          7186, Spring, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Advanced Organic Chemistry IIB
          7185, Fall, Graduate School of Science, 1
        • From 01 Apr. 2024, To 31 Mar. 2025
          Special study course II (Chemistry) 14
          5641, Year-long, Faculty of Science, 12
        • From 01 Apr. 2024, To 31 Mar. 2025
          Topics in Current Organic Chemistry
          7030, Fall, Graduate School of Science, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Organometallic Chemistry
          7029, Spring, Graduate School of Science, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Chemical Laboratory B
          8635, Fall, Faculty of Science, 8
        • From 01 Apr. 2023, To 31 Mar. 2024
          Basic Organic Chemistry I
          N347, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Organic Chemistry IID
          7187, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Organic Chemistry IIC
          7186, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Organic Chemistry IIB
          7185, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Organic Chemistry IIB
          7081, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Organic Chemistry IIA
          7080, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Organic Chemistry IIA
          7184, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Organic Chemistry IID
          7083, Fall, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Seminar on Organic Chemistry IIC
          7082, Spring, Graduate School of Science, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Special study course II (Chemistry) 14
          5641, Year-long, Faculty of Science, 12
        • From 01 Apr. 2023, To 31 Mar. 2024
          Topics in Current Organic Chemistry
          7030, Fall, Graduate School of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Organometallic Chemistry
          7029, Spring, Graduate School of Science, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Chemical Laboratory B
          8635, Fall, Faculty of Science, 8
        • From 01 Apr. 2022, To 31 Mar. 2023
          Basic Organic Chemistry II
          N348, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Organic Chemistry IIB
          7081, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Special study course II (Chemistry) 14
          5641, Year-long, Faculty of Science, 12
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Organic Chemistry IIA
          7080, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Organic Chemistry IID
          7083, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Topics in Current Organic Chemistry
          7030, Fall, Graduate School of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Chemical Laboratory B
          8635, Fall, Faculty of Science, 8
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Organic Chemistry IID
          7187, Fall, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Organometallic Chemistry
          7029, Spring, Graduate School of Science, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Organic Chemistry IIA
          7184, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Organic Chemistry IIC
          7186, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Seminar on Organic Chemistry IIC
          7082, Spring, Graduate School of Science, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Basic Organic Chemistry I
          N347, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Organic Chemistry IIB
          7185, Fall, Graduate School of Science, 1
        • From Apr. 2018, To Mar. 2019
          Special study course II (Chemistry) 14
          Year-long, 理学部
        • From Apr. 2018, To Mar. 2019
          Basic Organic Chemistry I
          Spring, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          Seminar on Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar on Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Organometallic Chemistry
          Fall, 理学研究科
        • From Apr. 2018, To Mar. 2019
          Topics in Current Organic Chemistry
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Special study course II (Chemistry) 14
          Year-long, 理学部
        • From Apr. 2019, To Mar. 2020
          Fundamental Chemical Experiments
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Basic Organic Chemistry I
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Seminar on Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar on Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Organometallic Chemistry
          Fall, 理学研究科
        • From Apr. 2019, To Mar. 2020
          Topics in Current Organic Chemistry
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Chemical Laboratory B
          Fall, 理学部
        • From Apr. 2020, To Mar. 2021
          Special study course II (Chemistry) 14
          Year-long, 理学部
        • From Apr. 2020, To Mar. 2021
          Basic Organic Chemistry I
          Spring, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          Basic Organic Chemistry II
          Fall, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          Seminar on Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar on Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Organometallic Chemistry
          Fall, 理学研究科
        • From Apr. 2020, To Mar. 2021
          Topics in Current Organic Chemistry
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Chemical Laboratory B
          Fall, 理学部
        • From Apr. 2021, To Mar. 2022
          Special study course II (Chemistry) 14
          Year-long, 理学部
        • From Apr. 2021, To Mar. 2022
          Basic Organic Chemistry I
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Basic Organic Chemistry II
          Fall, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Seminar on Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar on Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Organic Chemistry IIA
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Organic Chemistry IIB
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Organic Chemistry IIC
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Organic Chemistry IID
          Fall, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Organometallic Chemistry
          Spring, 理学研究科
        • From Apr. 2021, To Mar. 2022
          Topics in Current Organic Chemistry
          Fall, 理学研究科
        list
          Last Updated :2024/09/18

          Administration

          Faculty management (title, position)

          • From 01 Apr. 2024, To 31 Mar. 2025
            理学部・教育委員会委員
          • From 01 Apr. 2023, To 31 Mar. 2024
            理学部・教育委員会委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学部・教育委員会委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学部・教育委員会 入試専門小委員会委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学研究科SACRA広報・社会連携部門委員会委員
          • From 01 Apr. 2022, To 31 Mar. 2023
            理学研究科SACRA広報・社会連携部門委員会 社会連携小委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科国際・社会交流・広報委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科国際・社会交流・広報委員会 社会交流小委員会委員
          • From 01 Apr. 2018, To 31 Mar. 2019
            理学研究科国際・社会交流・広報委員会 社会交流小委員会 社会交流室・ELCASワーキンググループ
          • From 01 Apr. 2019, To 31 Mar. 2020
            理学研究科SACRA広報・社会連携部門委員会 社会連携小委員会委員
          • From 01 Apr. 2020, To 31 Mar. 2021
            理学部・教育委員会委員
          • From 01 Apr. 2020, To 31 Mar. 2021
            理学部・教育委員会 入試専門小委員会委員
          • From 01 Apr. 2020, To 31 Mar. 2021
            理学研究科SACRA広報・社会連携部門委員会 社会連携小委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学部・教育委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学部・教育委員会 入試専門小委員会委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            理学研究科SACRA広報・社会連携部門委員会 社会連携小委員会委員
          list
            Last Updated :2024/09/18

            Academic, Social Contribution

            Committee Memberships

            • From Apr. 2012, To Dec. 2017
              地区通信委員, 日本薬学会 ファルマシア誌
            • From Apr. 2010, To Mar. 2013
              トピックス小委員会, 日本薬学会 ファルマシア誌

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